DRG International Inc.

Nov 4, 2014

The ElizaMat-C2 performs automated Chemistry and ELISA

ElizaMat-CL performs automated ELISA and CLIA on one the same plate

User-programmable open system allows Customers the capability to utilize a wide range of CLIA, ELISA and Chemistry assays

ElizaMat®

makes all this possible…

World wide ElizaMat distributors have placed the analyzer’s for a variety of applications:

Clinical Laboratory Research – University Life

Sciences Wine Analysis Food & Grain Safety Water Quality Animal Safety

ElizaMat Applications

ElizaMat®

makes all this possible…

Microwells for all reactions CLIA, ELISA & Chemistry

Using Standard 96 Well Coated Plates or 8 Well Strips

ElizaMat ® C2• performs EIA and/or Biochemistry assays• includes plate washing system• fabricated-style enclosure with roll-up shield

Chemistry 200 tests per hour endpoint, or 170 per hour if all kinetic assays

ElizaMat CL – CLIA & ELISA 15 minutes to load a 96 well plate with samples and reagents washing the probe between each sample

(actual throughput depends upon incubation times)

ElizaMat Processing Capacity

When performing EIAs: ElizaMat schedules EIA tests to process by assays in strips.

You can place a different assay in each row as long as they share a common rack, and incubation temperature. Max. 12 assays per plate. Max. 2 wash buffers. The timing for the different assays can be different.

ElizaMat organizes the assay start times to prevent timing conflicts

ELISA Assays

ElizaMat Optical Design• 4 optical channels align

with 4 micro-wells

• Each well is read at all 8 wavelengths (340-750nm)

EIA & BioChemistry Modes

• Absorbance• Factor• Standard• Point to Point• Linear Regression• Cubic Spline (Constrained)• % Absorbance

• Cut- Off• Cut –Off Standard • Dose Response• Polynomials of different orders

ElizaMat®

Open system

Windows software

reagents samples Reactions

2 syringe pumps

Precisionoptical system

DI water

wash, rinse,and waste

bottles(not shown)

Wash features are not included in the Chemistry-

only Model 2902

Liquid Auto-sensingprobe

wash head

Standard Reagent & Sample racks are shown here,

Reagent racks may remain loaded for routine panels and removed for refrigeration.

Max height =100mm

ElizaMat automatically selects one of its 2 syringe

pumps, 50uL or 2.5mL

for pipetting and diluting

Probe tip detects liquid surface

ElizaMat estimates remaining volume.

Probe washes automatically after each use

Wash protocols are programmable, to prevent carryover.

Liquid Handling

SAMPLE-REAGENT PROBE:

* Reagent Volume inventory sensing

* Temperature controlled

* Retractable – crash protection

* Easy to replace probe

RCA-Reagent Cooling Accessory

Reagents go in Insulated rack

Reagents go in Insulated rack

Cooling unit attaches to ElizaMat ®

Rack slides on cooling tracks

Rack slides on cooling tracks

ElizaMat Automated Features • Fluid Handling - Precise Pipetting sample

volume as low as <2 uL (2uL to 1.95 mL)

• On-board pre-dilution & reflex testing

• No Carry-over with unique wash system • Incorporated incubation system & plate mixer

with plate Washer System• Reads four channels with eight filters with a

range of 340-700nm

ELIZAMAT SPECIFICATIONS

• AUTOMATED BIOCHEMISTRY CLIA AND EIA• 200 ENDPOINT OR 170 KINETIC REACTIONS PER

HOUR• VOLUME: 200 ΜL OR LESS• MAX SAMPLES: 96 (INCLUDES CALIBRATORS &

CONTROLS)• MAX REAGENTS: 27 TO 44 (PROGRAMMABLE)• THERMAL CONTROL: ROOM TEMPERATURE OR 37

ºC• COOLING CONTROL: OPTIONAL RCA, 2 TO 15 ºC• MONOCHROMATIC OR BICHROMATIC RESULTS• FILTERS: 340, 405, 450, 505, 545, 600, 630 AND

700 NM.• REQUIRES PC (XP, VISTA, WINDOWS 7 & 8)

The ElizaMat Software features allows:• Pausing the instrument to add sample or reagent, option of canceling commands

• Customizable test profiles and panels for specific test needs

• Language Selection file• Lock out for Assay Editor program• Data Storage – unlimited capacity• ElizaMat Manager – easy to use for calibration, QC, sample management and results reporting

ElizaMat Manager & Assay Editor Software

ElizaMat Manager & LIS Features

• ElizaMat Manager is used to run all the functions on the analyzer

• Provides user access to the run ElizaMat for sampling and reports in the lab.

• System is connected to a PC with a program that is easy to operate and works with Windows Operating System.

• LIS Connectivity for the Laboratory

Assay Editor Software used for Assay Programming

Sample Bio-chemistry programs are already available in the software. These can be used or make a copy and put changes into the copy.

Customers program their EIA kits

Technical support is available to all customers for technical needs

ElizaMat “Assay Editor” used for Programming assays

ElizaMat “Assay Editor” software simplifies assay programming

5 tabs help you locate the important screens. This is the Layout screen.

TABS

Layout, Calibration, Sample, Test List, Report

Sample Tab lets you add new samples and select assays for

them.

Test List Tab shows the queue so you can monitor any test in process

Quality ControlTracking

LIS compatible.Internet service and upgrades…and more

Self monitoring software and error messages Continuous communication logging between

Data Manager and the ElizaMat instrument Automatic utility that makes attachments for

emailing - test programs and error codes Automatic tests for filter voltage, pressure, and

many other parameters accessible to service technician

LEDs and other hardware and software indicators for tools-free diagnostics

Software upgrades from website

On-board service tools

ELIZAMAT- CL

NOW YOU CAN READ PLATES OR STRIPS,

ELISA OR CLIA IN A SINGLE

INSTRUMENT, EVEN WITHIN A SINGLE PLATE!!!

ELIZAMAT- CL

Patented optical system uses PMT (photomultiplier) to detect light signals from Luminescence and from 4 standard wavelengths for Absorbance.

The patented scan head prevents cross talk. You can program a wide range of CLIA assays and standard ELISA tests.

ELIZAMAT- CL

Fully automatedSingle Plate - Open systemProcesses ELISA and CLIA assays

THE ELIZAMAT-CL

THE ELIZAMAT-CL

Processes both, ELISA

and CLIA in a single plate!

THE ELIZAMAT-CL

Patented dual-function reader, automatically

switches between absorbance and luminescence

Intelligent software coordinates and

optimizes the timing of all assays

THE ELIZAMAT-CL

Software with identical look and feel

Plate Mixing IncubationSingle Sample/Reagent probe

COMMON ELEMENTS

Single readerReads RLUs (Relative Light Units) and absorbance

Eight-channel optic fiber bundle

NEW ELEMENTS

Patented dual-function reader, automatically switches between absorbance and luminescenceUser friendly SW for sample

processing samples and training for new operators

SELLING POINTS

Automatically process ELISA and CLIA in the

same plate in the same run

SELLING POINTS

The software automatically manages each assay

separately so that multiple assays can be processed on the same plate even if they

have different timings, reagents and reading modes

SELLING POINTS

Easy to operate High-precision pipetting Software prevents timing conflicts Complete QC package

ELIZAMAT-CL: IMPROVES QUALITY OF CARE

Adapt DRG reagents for application Consolidate two instruments in one No proprietary consumables Compact footprint saves bench space Robust design No disposable tips needed

ELIZAMAT-CL: COST EFFECTIVE OPERATION

Password security Patient database software included Unlimited number of customized

protocols LIS integration Flexible reporting styles

ELIZAMAT-CL: DATA MANAGEMENT

Self-monitoring of performanceSimple, economical maintenance

Built-in safety featuresLong-life IAD filters ISO13485, CE Marked, FDA

ELIZAMAT-CL: RELIABLE ANALYZER

FULLY AUTOMATED ELISA AND CLIA ASSAYS

IN ONE INSTRUMENT

PRODUCT PRESENTATION

ELIZAMAT- CL