Transcript
Page 1: Hair, Skin & Nails (Pack #8) skin & nails_uk... · skin, bones, nails and hair. • Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support

Hair, Skin & Nails (Pack #8) • Biotin • Collagen formula • Lipoic acid • Pycnogenol • Multivitamin

DESCRIPTION Hair, Skin & Nails pack (#8) of Functionalab, provides a comprehensive solution combining active beauty nutrients, antioxidants, vitamins and minerals for healthy, beautiful hair, skin and nails. This comprehensive pack includes Key ingredients combined together for optimal results;

• Biotin is a major contributor to healthy nails and hair.

• Collagen is a protein that plays a role in many places in the body, including skin, bones, nails and hair.

• Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support collagen production.

• Lipoic acid performs important metabolic and antioxidant functions in the body.

• Pycnogenol, a powerful antioxidant, helps scavenge free radicals prior to any damage from sun exposure.

CONTENT Functionalab’s line of Advanced Nutraceuticals offers potent nutrient blends of vitamins, minerals and other natural extracts to achieve

optimal health. Our health scientists have selected only the purest and highest quality natural ingredients to maximize effectiveness. Our Personalized Packs propose complete supplement solutions in daily packets that combine the perfect assortment of vitamins, nutrients and natural extracts tailored to individual profiles or objectives. Hair, Skin & Nails pack main objective to provide a comprehensive solution combining active beauty nutrients, antioxidants, vitamins and minerals for healthy, beautiful hair, skin and nails. This comprehensive pack includes:

• 2 Ultra Health multivitamin with over 50 nutritional ingredients to support optimal health and vitality

• 1 Collagen formula capsules to optimize collagen synthesis, collagen being a protein present in hair, skin and nails

• 1 Lipoic acid capsule, an antioxidant with important metabolic functions

• 1 Pycnogenol capsule, a powerful antioxidant that protects cells against free radical attacks

• 1 Hair, Skin & Nails tablet that nourishes and promotes healthy looking hair, skin and nails

FUNCTIONS

Page 2: Hair, Skin & Nails (Pack #8) skin & nails_uk... · skin, bones, nails and hair. • Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support

Studies show that a high percentage of adults eat less than the minimum daily recommendation of 10 or more essential nutrients. Adequate amounts and proper balance of these nutrients are needed not only for maintaining good health, but also for the dietary management of the body’s structure as well as the optimal functioning of the body, such as the immune and gastrointestinal systems. Ultra Health has been carefully developed to contain the right proportions of vitamins, minerals, trace elements, and other nutrients without danger of toxic build-up or other side effects. Collagen Formula is a specific combination of vitamin C with amino acids to support natural collagen production, which helps skin elasticity and hydration. Collagen Formula main objective is to support natural collagen production. Collagen is one of the key proteins, helping skin maintain its strength and elasticity. It is composed of a variety of amino acids, among them lysine and proline. Although the body can produce its own proline, lysine is an essential amino acid, meaning that the human body cannot synthesize it. The process by which lysine and proline are transformed into collagen requires Vitamin C (also known as ascorbic acid). Research has shown that when Vitamin C was added to the skin cells that make collagen, total collagen production is interestingly increased.

Lipoic acid is unique among biological antioxidants, because it is soluble in both water and lipids. This allows it to neutralize free radicals just about everywhere in the body, inside and outside the cells. Because alpha-lipoic acid is involved in so many different antioxidant functions in virtually all body tissues, it has been called the universal antioxidant. Besides being a universal free radical scavenger, alpha-lipoic acid can also recharge other antioxidant systems throughout the body. Also, it can extend the activity of vitamins C and E and regenerate glutathione. Pycnogenol is one of the most powerful natural free-radical scavengers yet discovered. As such, it reduces oxidative damage to vital tissues and helps maintain a healthy capillary system. Pycnogenol's antioxidant activity is many times more effective than that of vitamin C and vitamin E. Pycnogenol enhances the effectiveness of vitamins C and E and can be taken together with these vitamins for added benefit. The unique nutrient mixture supplied by Pycnogenol helps maintain a healthy capillary system in several ways. It protects vitamin C which is necessary for the production of ollagen. Pycnogenol can also naturally stimulate production of nitric oxide in blood vessels which is vital for supporting normal arterial health. Furthermore, Pycnogenol binds to

collagen fibers, protecting them from attack by free radicals so that the natural elasticity of collagen in skin, joints, arteries, capillaries and other tissues is maintained. Hair, Skin & Nails refreshes the body’s store of 11 active beauty ingredients that help nourish the hair, skin and nails. Vitamins A and C help scavenge for free radicals in the skin, aiming to neutralize them before damage can be done. Vitamin C also helps protect the skin from sun damage, which can lead to premature aging, and enhance the synthesis and protection of collagen, one of the key proteins that help skin maintain its strength and elasticity. Zinc has been shown to come to the rescue when skin has been damaged. Research into the cosmetic benefits shows that biotin may help improve the thickness and hardness of brittle nails, reducing the risk of splitting. Other studies on soya show that it can significantly improve the strength, manageability and overall appearance of hair, skin and nails, as rated by dermatologists.

Hair, Skin & nails pack (#8) is designed to support to nourish and to support healthy hair, skin and nails. This comprehensive pack is combining specific vitamins, minerals and other nutrients for optimal results.

Page 3: Hair, Skin & Nails (Pack #8) skin & nails_uk... · skin, bones, nails and hair. • Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support

SUGGESTED USE Take 1 pack per day with meals for a period of 3 months for optimal results. Do not exceed the recommended dose.

SIDE EFFECTS No adverse effects have been reported.

STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.

REFERENCES Brenner S, Horwitz C. Possible nutrient mediators in psoriasis and seborrheic dermatitis. II. Nutrient mediators: essential fatty acids; vitamins A, E and D; vitamins B1, B2, B6, niacin and biotin; vitamin C selenI.U.m; zinc; iron. World Rev Nutr Diet 1988;55:165-182. Chan S, Gerson B, Subramaniam S. The role of copper, molybdenum, selenium, and zinc in nutrition and health. Clin Lab Med 1998;18:673-85. Colombo VE, et al. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. J Am Acad Dermatol 1990;23(6 Pt 1):1127-32. Durlach J, Bac P, Durlach V, et al. Magnesium status and ageing: an update. Magnes Res 1998;11:25-42. Floersheim GL. Treatment of brittle fingernails with biotin. Z Hautkr. 1989;64(1):41-8. Reid IR. The roles of calcium and vitamin D in the prevention of osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98. Rico H, Gallego-Lago JL, Hernandez ER, et al. Effect of silicon supplement on osteopenia induced by ovariectomy in rats. Calcif Tissue Int 2000;66:53-5. Tabor A, Blair R (eds). Nutritional cosmetics: Beauty from within. 2009, William Andrew. Burlington, MA. pp.544. J Brennan LA, Morris GM, Wasson GR, et al. The effect of vitamin C or vitamin E supplementation on basal and H2O2- induced DNA damage in human lymphocytes. Br J Nutr 2000;84:195-202. Conconi MT, Tommasini M, Muratori E, Parnigotto PP. Essential amino acids increase the growth and alkaline phosphatase activity in osteoblasts cultured in vitro. Farmaco 2001 Oct;56(10):755-61 Hamilton IM, Gilmore WS, Benzie IF, et al. Interactions between vitamins C and E in human subjects. Br J Nutr 2000;84:261-7 Kurpad AV, Raj T, El-Khoury A, Beaumier L, Kuriyan R, Srivatsa A, Borgonha S, Selvaraj A, Regan MM, Young VR. Lysine requirements of healthy adult Indian subjects, measured by an indicator amino acid balance technique. Am J Clin Nutr 2001 May;73(5):900-7. Murad S, et al. Regulation of collagen synthesis by ascorbic acid. Proc Natl Acad Sci USA 1981;78(5):2879-2882. Otsuka M, Matsuzawa M, Ha TY, et al. Contribution of a high dose of L-ascorbic acid to carnitine synthesis in guinea pigs fed high-fat diets. J Nutr Sci Vitaminol (Tokyo) 1999;45:163-71. Tomblin FA and Lucas KH. Lysine for the management of herpes labialis. Am J Health Syst Pharm. 2001 Feb 15;58(4):298-300, 304. Giovannucci E, Stampfer MJ, Colditz GA, et al. Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study [see comments]. Ann Intern Med 1998;129:517-24. Hughes DA. Effects of dietary antioxidants on the immune function of middle-aged adults. Proc Nutr Soc 1999;58:79-84. Johnson K, Kligman EW. Preventive nutrition: an 'optimal' diet for older adults. Geriatrics 1992;47:56-60. Kelly GS. Nutritional and botanical interventions to assist with the adaptation to stress. Altern Med Rev 1999;4:249-65. Miranda MS, Cintra RG, Barros SB, et al. Antioxidant activity of the microalga Spirulina maxima. Braz J Med Biol Res 1998;31:1075-9. Mukhtar H, Ahmad N. Tea polyphenols: prevention of cancer

Page 4: Hair, Skin & Nails (Pack #8) skin & nails_uk... · skin, bones, nails and hair. • Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support

and optimizing health. Am J Clin Nutr 2000;71:1698S-1702S. Prior RL, Cao G. Antioxidant capacity and polyphenolic components of teas: implications for altering in vivo antioxidant status. Proc Soc Exp Biol Med 1999;220:255-61. Shobana S, Naidu KA. Antioxidant activity of selected Indian spices . Prostaglandins Leukot Essent Fatty Acids 2000;62:107-10. van Poppel G, Verhoeven DT, Verhagen H, et al. Brassica vegetables and cancer prevention. Epidemiology and mechanisms. Adv Exp Med Biol 1999;472:159-68. Weisburger JH. Approaches for chronic disease prevention based on current understanding of underlying mechanisms. Am J Clin Nutr 2000;71:1710S-1714S Araghi-Niknam M, Hosseini S, Larson D, Rohdewald P, Watson RR. Pine bark extract reduces platelet aggregation. Integ Med 2: 73-77, 1999. Arcangeli P. Pycnogenol® in chronic venous insufficiency. Fitoter 71: 236-244, 2000. Belcaro G, Cesarone MR, Errichi BM, Ledda A, Di Renzo A, Stuard S, Dugall M, Pellegrini L, Rohdewald P, Ippolito E, Ricci A, Cacchio M, Ruffini I, Fano F and Hosoi M. Venous Ulcers: Microcirculatory Improvement and Faster Healing with Local Use of Pycnogenol. Angiology 56: 699-705, 2005. Cisár P, Jány R, Waczulíková I, Sumegová K, Muchová J, Vojtassák J, Duracková Z, Lisy M, Rohdewald P. Effect of Pine Bark Extract (Pycnogenol�) on Symptoms of Knee Osteoarthritis. Phytother Res 22: 1087-1092, 2008. Farid R, Mifteizi Z, Mirheidari M, Yazdi S, Torghabeh H, Esmaelli H, Zibadi S, Rohdewald P, Watson RR. Pycnogenol® supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritis. Nutrition Research 27: 692-697, 2007. Hosseini S, Lee J, Sepulveda RT, Rohdewald P, Watson RR. A Randomized, double blind, placebo controlled, prospective, 16 week crossover study to determine the role of Pycnogenol® in modifying blood pressure in mildly hypertensive patients. Nutr Res 21: 1251-1260, 2001. Koch R. Comparative study of Venostasin® and Pycnogenol® for treatment in chronic venous insufficiency. Phytother Res 16:1-5, 2002. Kohama T, Suzuki N, Ohno S, Inoue M. Analgesic efficacy of Pycnogenol® in dysmenorrhea. An open clinical trial. J Reprod Med 49: 828-832, 2004. Kohama T, Herai K, Inoue M. The Effect of Pycnogenol® on Endometriosis as Compared with Leuprorelin Acetate. J Reprod Med 52: 703-708, 2007. Rohdewald P. A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse pharmacology. Int J Clin Pharmacol Ther 40(4): 158-168, 2002. Saliou C, Rimbach G, Moini H, McLaughlin L, Hosseini S, Lee J, Watson RR, Packer L (2001) Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-Bdependent gene expression in keratinocytes are modulated by a French maritime pine bark extract. Free Rad Biol Med 30: 154-160, 2001. Schäfer A, Chovanová Z, Muchová J, Sumegová K, Liptákova A, Duracková Z, Högger P. Inhibition of COX-1 and COX-2 activity by plasma of human volunteers after ingestion of French maritime pine bark extract (Pycnogenol). Biomed Pharmacother 60: 5-9, 2006. Schönlau F, Rohdewald P. Pycnogenol® for diabetic retinopathy. A review. Int Ophthal 24: 161-171, 2002.

Vinciguerra G, Belcaro G, Cesarone R, Rohdewald P, Stuard S, Ricci A, Di Renzo A, Hosoi M, Dugall M, Ledda A, Cacchio M, Acerbi G, Fano F. Cramps and Muscular Pain: Prevention with Pycnogenol in Normal Subjects, Venous Patients, Athletes, Claudicants and in Diabetic Microangiopathy. Angiology 57: 331-339, 2006. Watson RR. Pycnogenol® and cardiovascular health. Review. Evidence Based Integr Med 1: 27-32, 2003. Zibadi S, Rohdewald PJ, Park D, Watson RR. Reduction of cardiovascular risk factors in subjects with type 2 diabetes by Pycnogenol supplementation. Nutrition Research 28: 315- 320, 2008. Ames BN. Micronutrients prevent cancer and delay aging. Toxicol Lett 1998;102-103:5-18. Anuradha B, Varalakshmi P. Activities of glucose-metabolizing enzymes in experimental neurotoxic models with lipoate as an alleviator. J Appl Toxicol 1999;19:405-409. Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories [In Process Citation]. Med Klin 1999;94 Suppl 3:84-9. Borcea V, Nourooz-Zadeh J, Wolff SP, Klevesath M, Hofmann M, Urich H, Wahl P, Ziegler R, Tritschler H, Halliwell B, Nawroth PP. alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria. Free Radic Biol Med 1999;26:1495-500. Bustamante J, Lodge JK, Marcocci L, Tritschler HJ, Packer L, Rihn BH. Alpha-lipoic acid in liver metabolism and disease. Free Radic Biol Med 1998;24:1023-39. Cameron NE, Cotter MA, Horrobin DH, Tritschler HJ. Effects of alphalipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. Diabetologia 1998;41:390-9. Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB. (R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate. Faseb J 1999;13:411-8. Henriksen EJ, Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ. Stimulation by alpha-lipoic acid of glucose transport activity in skeletal muscle of lean and obese Zucker rats. Life Sci 1997;61:805-12. Hong YS, Jacobia SJ, Packer L, Patel MS. The inhibitory effects of lipoic compounds on mammalian pyruvate dehydrogenase complex and its catalytic components. Free Radic Biol Med 1999;26:685-94. Jacob S, Ruus P, Hermann R, Tritschler HJ, Maerker E, Renn W, Augustin HJ, Dietze GJ, Rett K. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo- controlled pilot trial [In Process Citation]. Free Radic Biol Med 1999;27:309-14. Jacob S, Streeper RS, Fogt DL, Hokama JY, Tritschler HJ, Dietze GJ, Henriksen EJ. The antioxidant alpha-lipoic acid enhances insulinstimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes 1996;45:1024-9. Kelly GS. Nutritional and botanical interventions to assist with the adaptation to stress. Altern Med Rev 1999;4:249-65. Khanna S, Roy S, Packer L, Sen CK. Cytokine-induced glucose uptake in skeletal muscle: redox regulation and the role of alpha-lipoic acid. Am J Physiol 1999;276:R1327-33. Konrad T, Vicini P, Kusterer K, Hoflich A, Assadkhani A, Bohles HJ, Sewell A, Tritschler HJ, Cobelli C, Usadel KH. alpha-Lipoic acid treatment decreases serum lactate and

Page 5: Hair, Skin & Nails (Pack #8) skin & nails_uk... · skin, bones, nails and hair. • Collagen formula is made of Vitamin C and 2 amino-acids, L-Lysine and L-Proline that help support

pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes. Diabetes Care 1999;22:280-7. Lodge JK, Traber MG, Packer L. Thiol chelation of Cu2+ by dihydrolipoic acid prevents human low density lipoprotein peroxidation. Free Radic Biol Med 1998;25:287-97. Lykkesfeldt J, Hagen TM, Vinarsky V, Ames BN. Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation. Faseb J 1998;12:1183-9. Mitsui Y, Schmelzer JD, Zollman PJ, Mitsui M, Tritschler HJ, Low PA.Alpha-lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve. J Neurol Sci 1999;163:11-6. Nagamatsu M, Nickander KK, Schmelzer JD, Raya A, Wittrock DA, Tritschler H, Low PA. Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 1995;18:1160-7. Ou P, Nourooz-Zadeh J, Tritschler HJ, Wolff S. Activation of aldose reductase in rat lens and metal-ion chelation by aldose reductase inhibitors and lipoic acid. Free Radic Res 1996;25:337-46. Packer L. alpha-Lipoic acid: a metabolic antioxidant which regulates NFkappa B signal transduction and protects against oxidative injury. Drug Metab Rev 1998;30:245-75. Sen CK, Tirosh O, Roy S, Kobayashi MS, Packer L. A positively charged alpha-lipoic acid analogue with increased cellular uptake and more potent immunomodulatory activity. Biochem Biophys Res Commun 1998;247:223-8.

Streeper RS, Henriksen EJ, Jacob S, Hokama JY, Fogt DL, Tritschler HJ.Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am J Physiol 1997;273:E185-91. Strokov IA, Kozlova NA, Mozolevskii Iu V, Miasoedov SP, Iakhno NN. [The efficacy of the intravenous administration of the trometamol salt of thioctic (alpha-lipoic) acid in diabetic neuropathy]. Zh Nevrol Psikhiatr Im S S Korsakova 1999;99:18-22. Thurich T, Bereiter-Hahn J, Schneider M, Zimmer G. Cardioprotective effects of dihydrolipoic acid and tocopherol in right heart hypertrophy during oxidative stress. Arzneimittelforschung 1998;48:13-21. Tirosh O, Sen CK, Roy S, Kobayashi MS, Packer L. Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue. Free Radic Biol Med 1999;26:1418-26. Tomlinson DR. Future prevention and treatment of diabetic neuropathy. Diabetes Metab 1998;24 Suppl 3:79-83. Wiznitzer A, Ayalon N, Hershkovitz R, Khamaisi M, Reece EA, Trischler H, Bashan N. Lipoic acid prevention of neural tube defects in offspring of rats with streptozocin-induced diabetes. Am J Obstet Gynecol 1999;180:188-93. Ziegler D, Hanefeld M, Ruhnau KJ, Hasche H, Lobisch M, Schutte K, Kerum G, Malessa R. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha- Lipoic Acid in Diabetic Neuropathy [In Process Citation]. Diabetes Care 1999;22:1296-301.

www.functionalab.com 1-866-969-7068

This product is not intended to diagnose, treat, cure, or prevent any disease.


Top Related