Download - Deep brain stimulation presentation
![Page 1: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/1.jpg)
Deep Brain Stimulation
Presented by:
Debasish Mondal
4th year BME,NSEC4/7/2017 1Deep Brain Stimulation
![Page 2: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/2.jpg)
CONTENTS
• INTRODUCTION• DISEASES TREATED USING DBS• COMPONENTS• PLACEMENT OF THE COMPONENTS• METHODOLOGY OF SURGERY• LIMITATIONS OF DBS SURGERY• RISK OF DBS SURGERY• FUTURE SCOPE AND ENHANCEMENT• CONCLUSIONS• MANUFACTURING COMPANIES• REFERENCES
4/7/2017 2Deep Brain Stimulation
![Page 3: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/3.jpg)
What is Deep Brain Stimulation?
• Deep Brain Stimulation(DBS) is a surgical treatment which implants a medical device called a Brain Pacemaker.
• DBS sends electrical impulse to specific parts of the brain which need to be stimulated
4/7/2017 3Deep Brain Stimulation
![Page 4: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/4.jpg)
Illnesses Treated
DBS in selected brain regions has provided effective benefits for the diseases such as,
(i) Parkinson’s Disease
(ii) Chronic pain
(iii) Tremor
(iv) Dystonia
4/7/2017 4Deep Brain Stimulation
![Page 5: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/5.jpg)
Target sites of Brain
4/7/2017 5Deep Brain Stimulation
![Page 6: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/6.jpg)
Components of DBS
The pacemaker consist of
• Electrodes
• Lead wire
• Pulse generator
4/7/2017 6Deep Brain Stimulation
![Page 7: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/7.jpg)
Methodology of Surgery
• Step 1:Attachment of stereotactic frame.
• Step 2: Take MRI or CT scan
• Step 3: Skin and Skull incision
• Step 4: Insert electrode in the brain
• Step 5. Stimulate the brain cells
• Step 6: Closure
4/7/2017 7Deep Brain Stimulation
![Page 8: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/8.jpg)
Fig-I Fig-II
Fig-III Fig-IV
4/7/2017 8Deep Brain Stimulation
![Page 9: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/9.jpg)
Limitations of DBS surgery
• It is expensive
• The selection of patients. DBS is not used in the following patients,
Patients with a previous Surgical Ablation procedure
Patients who are pregnant
Patients under the age of 18 and above
the age of 75.
4/7/2017 9Deep Brain Stimulation
![Page 10: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/10.jpg)
Risks
Risks associated with surgery• Intracranial Bleeds (12%)• Seizures (3%)• Headaches (25%)• Infection (6%)
Device complications• Probe replacement (9%)• Wire replacement (6%)• Repositioning of the probe (8%)• Replacement of pulse generator (17%)• Risk of Death < 1%
4/7/2017 10Deep Brain Stimulation
![Page 11: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/11.jpg)
Benefits
• Reduce their medications , thus minimizing the side effects of drugs.
• Electrical impulses can be adjusted.
• Both cardiac pacemaker and brain pacemaker can be used simultaneously by the same person.
4/7/2017 11Deep Brain Stimulation
![Page 12: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/12.jpg)
Future scope and Enhancement
• Focuses on,
The device which automatically senses the need for increased voltage.
Improving longevity.
Reduction in size.
Reduction in cost.
Low risk.
4/7/2017 12Deep Brain Stimulation
![Page 13: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/13.jpg)
Manufacturing companies
4/7/2017 13Deep Brain Stimulation
![Page 14: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/14.jpg)
Conclusions
• Advances in the neurosciences will continue to drive the applications of DBS.
• Finally, innovations in biomedical engineering and technology will continue to be applied to DBS.
• The ideal platform for the development of these innovations is the active collaboration between basic scientists, engineers and clinicians.
4/7/2017 14Deep Brain Stimulation
![Page 15: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/15.jpg)
References
• http://www.medscape.com/viewarticle/813942_3
• https://www.ncbi.nlm.nih.gov/pubmed/24175861
• https://en.wikipedia.org/wiki/Dystonia
• http://journal.frontiersin.org/article/10.3389/fnins.2016.00173/full
• http://alliancebiomedica.com/index.php?route=product
• BOOK: Clinical Physiology By U K Mishra & J Kalita
4/7/2017 15Deep Brain Stimulation
![Page 16: Deep brain stimulation presentation](https://reader033.vdocuments.mx/reader033/viewer/2022051521/5a658d6d7f8b9a02158b4f3d/html5/thumbnails/16.jpg)
4/7/2017 16Deep Brain Stimulation