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JOURNAL OF EQUINE VETERINARY SCIENCE228

The Physiological Basis of Veteri-nary Clinical Pharmacology (2001); by J. Desmond Baggot; published by Blackwell Science (Iowa State University Press); 6 1/2” x 9 1/2” hardbound; 283 pages; $72.95.

The diversity of species in which drugs are used for clinical purposes and the emphasis on various classes of drugs make veterinary pharmacology a complex subject. Anatomical and physiological features influence the pharmacokinetic behavior of a drug in a particular animal and the dosage required. This book is concerned with the basis of species differences, the selection of pharmacokinetic parameters and the interpretation of values obtained. There are chapters on bioavailability and its application to veterinary dosage forms, changes in drug disposition and interspecies scaling, clinical selectivity and stereoisomerism, drug permeation, antimicrobial disposition and specifics related to neonatal animals.

The author has gathered all this information together in one place so allowing the reader to make a better selection of drug preparations for animal

dosages to effectively treat animal diseases. The book will prove valuable to clinical researchers in the areas of pharmacology, anesthesia, microbial infections and internal medicine as well as postgraduate students of these disciplines.

Dr. Baggot is a former Professor of Clinical Pharmacology at the School of Veterinary Medicine, University of California, Davis, and is currently Visiting Professor of Veterinary Phar-macology at the School of Veterinary Medicine, St. George’s University, Grenada, West Indies.

Atlas of Veterinary Hematology: Blood and Bone Marrow of Domestic Animals (2001); by John W. Harvey; published by W. B. Saunders; 7” x 10” paperback; 228 pages; $57.00.

This color atlas is designed as a reference for the morphologic aspects of veterinary hematology of common domestic animals. It covers a variety of species, including dogs, cats, horses, cattle, sheep, goats, pigs and llamas. The atlas is divided into two sections; the first covers blood, while the second discusses bone marrow. Techniques for the collection and preparation of blood and bone marrow spears and bone marrow core biopsies are covered, in addition to the morphology of the tissues collected. Often, multiple examples of a cell type or abnormal condition are shown to illustrate the variance in morphology.

The book includes nearly 600 high quality color images that enhance the recognition of cell types, inclu-sions and conditions. Hematology of a variety of small and large animals is included. There are multiple examples of cell types and condi-tions demonstrating the variability in morphology that naturally occurs. Accompanying text includes an extensive bibliography to detail the

importance of abnormal findings and provide documentation and additional sources of information.

Kirk and Bistner’s Handbook of Veterinary Procedures and Emergency Treatment; Seventh edition (2000); by Stephen I. Bistner, Richard B. Ford, and Mark R. Raffe; published by W. B. Saunders; 5” x 8”; 1022 pages; $59.00.

It was just over 30 years ago that Drs. Kirk and Bistner edited the first edition of the Handbook of Veterinary Procedures and Emergency Treatment. This new edition exhibits the philosophy and objectives; to provide an efficient, highly practical resource fundamental in today’s practice environment.

“Looking back at the original 1969 edition offers some striking insights into the many changes introduced into the profession over this relatively short period,” the authors observe. “It was a time when only four vaccines existed for dogs, when ether and phencyclidine were listed in the chart of ‘Common Drug Doses,’ and when a discussion of electrocardiography could be published, in its entirety, on page 143. Indeed, things have changed.”

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