© Cengage Learning 2016 © Cengage Learning 2016
Eric J. MashDavid A. Wolfe
Attention-Deficit/HyperactivityDisorder (ADHD)
8
© Cengage Learning 2016
• Attention-deficit/hyperactivity disorder (ADHD) is exhibited as persistent age-inappropriate symptoms of inattention, hyperactivity, and impulsivity that are sufficient to cause impairment in major life activities– Characteristic behaviors vary considerably
from child to child
– Different behavior patterns may have different causes
Description
© Cengage Learning 2016
• Early 1900s – Children who lacked self-control and showed
symptoms of overactivity/inattention in school were said to have poor “inhibitory volition” and “defective moral control”
• Following the worldwide influenza epidemic from 1917-1926– “Brain-injured child syndrome”
• 1940s-1950s: “minimal brain damage” and “minimal brain dysfunction”
History
© Cengage Learning 2016
Historical Example
© Cengage Learning 2016
• Late 1950s – ADHD was called hyperkinesis
• Led to definition of hyperactive child syndrome, in
• By the 1970s– Deficits in attention and impulse control, in
addition to hyperactivity, were seen as the primary symptoms
• 1980s saw increased interest in ADHD– Rise in stimulant use generated controversy
History (cont’d.)
© Cengage Learning 2016
• Key symptoms fall under two well-documented categories– Inattention
– Hyperactivity-impulsivity
• Using these dimensions to define ADHD oversimplifies the disorder– Attention and impulse control are closely
connected developmentally
Core Characteristics
© Cengage Learning 2016
DSM-V Diagnostic Criteria for ADHD
© Cengage Learning 2016
DSM-V Diagnostic Criteria for ADHD (cont’d.)
© Cengage Learning 2016
DSM-V Diagnostic Criteria for ADHD (cont’d.)
© Cengage Learning 2016
• Inability to sustain attention, particularly for repetitive, structured, and less enjoyable tasks
• Deficits may be seen in one or more types of attention– Attentional capacity
– Selective attention
– Distractibility
– Sustained attention/vigilance (a core feature)
Inattention
© Cengage Learning 2016
• Inability to voluntarily inhibit dominant or ongoing behavior
• Hyperactive behaviors include– Fidgeting and difficulty staying seated
– Moving, running, touching everything in sight, excessive talking, and pencil tapping
– Excessively energetic, intense, inappropriate, and not goal-directed
Hyperactivity-Impulsivity
© Cengage Learning 2016
• Impulsivity – Inability to control immediate reactions or to
think before acting
– Cognitive impulsivity includes disorganization, hurried thinking, and need for supervision
– Behavioral impulsivity includes difficulty inhibiting responses when situations require it
– Emotional impulsivity includes impatience, low frustration tolerance, hot temper, quickness to anger, and irritability
Hyperactivity-Impulsivity (cont’d.)
© Cengage Learning 2016
• Predominantly inattentive presentation (ADHD-PI)
• Predominantly hyperactive–impulsive presentation (ADHD-HI)
• Combined presentation (ADHD-C)
ADHD Presentation Types
© Cengage Learning 2016
• Inattentive, drowsy, daydreamy, spacey, in a fog, and easily confused
• May have learning disability, process information slowly, have trouble remembering things, and display low academic achievement
• Often anxious, apprehensive, socially withdrawn, and may display mood disorders
Predominantly Inattentive Type (ADHD-PI)
© Cengage Learning 2016
• Primarily symptoms of hyperactivity-impulsivity (rarest group)
• Primarily includes preschoolers and may have limited validity for older children
• May be a distinct subtype of ADHD-C
Predominantly Hyperactive-Impulsive Type (ADHD-HI)
© Cengage Learning 2016
• Children who have symptoms of both inattention and hyperactivity-impulsivity
• Most often referred for treatment
Combined Type (ADHD-C)
© Cengage Learning 2016
• Appears prior to age 12
• Persists more than 6 months
• Occurs more often and with greater severity than in:– Other children of the same age and sex
• Occur across two or more settings
• Interferes with social or academic performance
• Not explained by another disorder
Additional DSM Criteria
© Cengage Learning 2016
• Limitations of DSM criteria for ADHD– Developmentally insensitive
– Categorical view of ADHD
• DSM criteria shape our understanding of ADHD– DSM criteria are also shaped by, and in some
instances lag behind, new research findings
What DSM Criteria Don’t Tell Us
© Cengage Learning 2016
• Children with ADHD often display other problems in addition to their primary difficulties– Cognitive deficits
– Speech and language impairments
– Developmental coordination and tic disorders
– Medical and physical concerns
– Social problems
Associated Characteristics
© Cengage Learning 2016
• Cognitive processes
• Language processes
• Motor processes
• Emotional processes
Cognitive Deficits: Executive Functions
© Cengage Learning 2016
Examples of Impaired Executive Functions
© Cengage Learning 2016
• Intellectual deficits – Most children with ADHD have at least normal
intelligence - the difficulty lies in applying intelligence to everyday life situations
• Impaired academic functioning– Children with ADHD frequently have lower
productivity, grades, and scores on achievement tests
Cognitive Deficits: Intellectual and Academic
© Cengage Learning 2016
• Learning disorders are common for children with ADHD– Problem areas: reading, spelling, and math
• Distorted self-perceptions – Positive bias: exaggeration of one’s
competence
– Self-esteem in children with ADHD may vary with the subtype of ADHD
– Distortions in perceptions of quality of life
Cognitive Deficits: Learning Disorders and Self-Perceptions
© Cengage Learning 2016
• Formal speech and language disorders
• Difficulty understanding others’ speech
• Excessive and loud talking
• Frequent shifts and interruptions in conversation
• Inability to listen
• Inappropriate conversations
• Speech production errors
Speech and Language Impairments
© Cengage Learning 2016
• As many as 30-50% of children with ADHD display motor coordination difficulties– Clumsiness, poor performance in sports, or
poor handwriting
• Overlap exists between ADHD and developmental coordination disorder (DCD)– Marked motor incoordination and delays in
achieving motor milestones
Developmental Coordination and Tic Disorders
© Cengage Learning 2016
• Tic disorders occur in 20% of children with ADHD– Sudden, repetitive, nonrhythmic motor
movements or sounds such as eye blinking, facial grimacing, throat clearing, and grunting
Developmental Coordination and Tic Disorders (cont’d.)
© Cengage Learning 2016
• Health-related problems– Higher rates of asthma and bedwetting
• Studies’ findings are inconsistent
– Sleep disturbances may be related to use of stimulant medications and/or co-occurring conduct or anxiety disorders
Medical and Physical Concerns
© Cengage Learning 2016
• Accident-proneness and risk taking– Over 50% are described as being accident-
prone
– At higher risk for traffic accidents
– At risk for early initiation of cigarette smoking, substance use disorders, and risky sexual behaviors
– Reduced life expectancy
– Higher medical costs
Medical and Physical Concerns (cont’d.)
© Cengage Learning 2016
• Family problems include:– Negativity, child noncompliance, excessive
parental control, sibling conflict, maternal depression, paternal antisocial behavior, and marital conflict
• Family difficulties may be due to co-occurring conduct problems
Social Problems
© Cengage Learning 2016
• Peer problems – ADHD children can be bothersome, stubborn,
socially awkward, and socially insensitive• They are often disliked and uniformly rejected by
peers, have few friends
• They are unable to apply their social understanding in social situations
• Positive friendships may buffer negative outcomes
Social Problems (cont’d.)
© Cengage Learning 2016
• Up to 80% of children with ADHD have a co-occurring psychological disorder
• Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD)– Role of COMT gene
– A common genetic contribution for ADHD, ODD, and CD
– Family connections – there is evidence for a contribution from a shared environment
Accompanying Psychological Disorders and Symptoms
© Cengage Learning 2016
• Anxiety disorders– About 25% of children with ADHD experience
excessive anxiety
– Co-occurring anxiety worsens symptoms or severity of ADHD
• Findings are inconsistent
– Children with co-occurring ADHD and anxiety:• Display social and academic difficulties
• Experience greater long-term impairment and mental health problems
Accompanying Psychological Disorders and Symptoms Anxiety Disorders
© Cengage Learning 2016
• Mood disorders– ADHD at 4-6 years is a risk factor for future
depression and suicidal behavior
– 20-30% of children with ADHD experience depression
• Family risk for one disorder may increase the risk for the other
• Controversy regarding relationship between ADHD and pediatric bipolar disorder (BP)
Accompanying Psychological Disorders and Symptoms Mood Disorders
© Cengage Learning 2016
• Prevalence rates vary widely with sampling methods– Estimates: 6-7% of school-age children and
adolescents in North America and 5% worldwide have ADHD
– ADHD is one of the most common referral problems seen at clinics
Prevalence and Course
© Cengage Learning 2016
• ADHD occurs more frequently in boys
• Overall rates decrease in adolescence for both sexes - ratio remains the same
• Ratio in clinical samples is 6:1 with boys being referred more often than girls– ADHD in girls may go unrecognized and
unreported
• DSM criteria (cutoffs and symptoms) may be more appropriate to boys than girls
Gender
© Cengage Learning 2016
• Girls with ADHD may be more likely to display inattentive/disorganized symptoms
• Clinic-referred school-age children with ADHD display similar symptoms
• Girls with ADHD who display impulsive-hyperactive behaviors– More likely to develop eating disorder
symptoms
Gender (cont’d.)
© Cengage Learning 2016
• ADHD affects children from all social classes– Slightly more prevalent among lower SES
groups
• Findings are inconsistent regarding relationships among ADHD, race, and ethnicity
• ADHS is found in all countries and cultures– Rates vary
Socioeconomic Status and Culture
© Cengage Learning 2016
• Cultural differences may reflect cultural norms and tolerance for ADHD symptoms
• ADHD is a universal phenomenon that is diagnosed more often in boys than girls in all cultures– Expression, associated features, impairments,
and outcomes are quite similar wherever it occurs
Socioeconomic Status and Culture (cont’d.)
© Cengage Learning 2016
• Infancy– Signs of ADHD may be present at birth - no
reliable or valid methods exist to identify it
• Preschool – Hyperactivity-impulsivity symptoms become
more visible and significant at ages 3-4
– Children with symptoms for at least 1 year are likely to continue to have difficulties later in middle childhood and adolescence
Course and Outcome
© Cengage Learning 2016
• Symptoms are especially evident when the child starts school
• Oppositional defiant behaviors may increase or develop– By age 8-12, defiance and hostility may take
the form of serious problems– Increased problems may encompass self-
care, personal responsibility, chores, trustworthiness, independence, social relationships, and academic performance
Course and Outcome Elementary School
© Cengage Learning 2016
• Many children with ADHD do not outgrow problems and some can get much worse
• At least 50% of clinic-referred elementary school children continue to suffer from ADHD into adolescence
• Adult challenges – Some individuals either outgrow or learn to
cope with their disorder by adulthood
– ADHD is established as an adult disorder
Course and Outcome Adolescence and Adulthood
© Cengage Learning 2016
• Explanations for ADHD– Trait from evolutionary past as hunters
– ADHD is a myth fabricated because society needs it
– Some theories• Cognitive functioning deficits
• Reward/motivation deficits
• Arousal level deficits
• Self-regulation deficits
Theories and Causes
© Cengage Learning 2016
A Possible Developmental Pathway for ADHD
© Cengage Learning 2016
• ADHD runs in families
• Adoption studies
• Twin studies – 75% heritability estimates for hyperactive-
impulsive and inattentive behaviors
• Specific gene studies– Genes may contribute to the expression of
ADHD – focus on dopamine regulation
Genetic Influences
© Cengage Learning 2016
• Factors that compromise development of the nervous system before and after birth may be related to ADHD
• Mother’s use of cigarettes, alcohol, or other drugs during pregnancy are associated with ADHD– Contributing factors, rather than a causal
association
– It is difficult to disentangle substance abuse influence and other environmental factors
Pregnancy, Birth, and Early Development
© Cengage Learning 2016
• Research shows differences on:– Psychophysiological measures
• Diminished arousal or arousability
– Measures of brain activity during vigilance tests
• Under-responsiveness to stimuli/deficits in response inhibition
– Blood flow to prefrontal regions and pathways connecting them to limbic system
• Decreased blood flow to these regions
Neurobiological Factors
© Cengage Learning 2016
• Abnormalities primarily in the frontostriatal circuitry are implicated– This region includes the prefrontal cortex and
the basal ganglia
– ADHD children have smaller total and right cerebral volumes (by 3-4%), smaller cerebellum, and delayed brain maturation
• Specific regions of the thalamus may also be involved
Brain Abnormalities
© Cengage Learning 2016
• No consistent differences have been found between children with and without ADHD– Some neurotransmitters may be involved
• Dopamine, norepinephrine, epinephrine, and serotonin may be involved
• Most evidence suggests a selective deficiency in availability of dopamine and norepinephrine
– Using medication for effective treatment of ADHD symptoms does not prove that deficits are the cause of symptoms
Neurophysiological and Neurochemical Associations
© Cengage Learning 2016
• Sugar is not the cause of hyperactivity
• Allergic reactions and diet– Possible moderating role of genetic factors
may explain why food additives affect the behavior of some children
• Low levels of lead may be associated with ADHD symptoms
• The role of diet, allergy, and lead as primary causes of ADHD is minimal to nonexistent
Diet, Allergy, and Lead
© Cengage Learning 2016
• Importance of family influences– Family influences may lead to ADHD
symptoms or to a greater severity of symptoms
– Family problems may result from interacting with a child who is difficult to manage
– Family conflict is likely related to the presence, persistence, or later emergence of associated oppositional and conduct disorder
Family Influences
© Cengage Learning 2016
• Less than half of the children with ADHD receive treatment– Of those who receive treatment, many
discontinue prematurely
• The primary treatment approach combines:– Stimulant medication
– Parent management training
– Educational intervention
Treatment
© Cengage Learning 2016
Treatments for Children with ADHD
© Cengage Learning 2016
• Stimulants have been used to treat ADHD since the 1930s – Among the most effective stimulants are
dextroamphetamine and methylphenidate• May help normalize frontostriatal structural
abnormalities and functional connections
– Effects are temporary and occur only while medication is taken; beneficial in short-term
• Questions surround long-term benefits and later adjustment
Medication
© Cengage Learning 2016
• Provides parents with a variety of skills– Managing the child’s oppositional and
noncompliant behaviors
– Coping with emotional demands of raising a child with ADHD
– Containing the problem so it does not worsen
– Keeping the problem from adversely affecting other family members
Parent Management Training (PMT)
© Cengage Learning 2016
• Parents are:– Taught to understand biological basis of
ADHD
– Given set of guiding principles
– Taught behavior management principles and techniques
– Encouraged to spend time each day sharing enjoyable activity with their child
– Taught how to reduce their own levels of arousal
Parent Management Training (PMT) (cont’d.)
© Cengage Learning 2016
• Teacher and child must set realistic goals and objectives
• Response-cost procedures are used to reduce disruptive or off-task behaviors
• Many strategies are basic good teaching methods
• School-based interventions for ADHD have received considerable support
Educational Intervention
© Cengage Learning 2016
• Summer treatment programs– Maximize opportunities to build effective peer
relations in normal settings and provides continuity with academic work so gains from school year aren’t lost
– Are coordinated with stimulant medication trials, PMT, social skills training, and educational interventions
Intensive Interventions
© Cengage Learning 2016
• Family counseling and support groups – Help family members develop new skills,
attitudes, and ability to relate more effectively
• Individual counseling– Helps children with ADHD deal with their
problems and feelings of isolation and abnormality
– Helps build their sense of self-competence
Additional Interventions
© Cengage Learning 2016
• Children with ADHD have problems that should not be minimized
• Each child is unique and has assets and resources that need to be recognized and supported
Keeping Things in Perspective