dna.land: know your genome, help science
TRANSCRIPT
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1Dina Zielinski Roots Tech 3 February 2016
@dinazielinski @dl1dl1
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Proband Grandmother
Cousin
Exonic mutations
23,175 22,252 22,746
Rare mutations
660 591 646
Harmful 358 308 331 Shared
8 variations
Goldenhar Syndrome
Hemifacial microsomia
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
If it takes a village to raise a child…
…it takes the world to help a child with a genetic disorder
image: Victor Ngai
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
feedback reciprocity
genealogy
crowd sourcing
data sharing
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
https://dna.land
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land consent
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
• Short + animated• Balanced • Skin in the game
DNA.Land consent
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land consent
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
legalgenealogist.com
“But from the standpoint of the rules of the road, there’s no reason not to consider playing in the DNA.Land playground.”
Judy G. Russell, JD
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
feedback reciprocity
genealogy
crowd sourcing
data sharing
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land features
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
User reports
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Ancestry report
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Ancestry
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Relative matching
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Relative matching
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Relative matching
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Relative matching
90% of users have at least one match
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land features in depth
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
imputation
26 possible solutions8 make actual words1 probable solution
You had a blue ca_ on your head. p
You had a blue ca_ yesterday.
b,n,p,r,t?
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Power to detect recent common ancestry between pairs of individuals known to be related at varying degrees.
Chad D. Huff et al. Genome Res. 2011;21:768-774
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
NEW FEATURES
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Relatives of relatives
Dena
Bruce
Cherie
Cherie
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
Import Geni profile
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
feedback reciprocity
genealogy
crowd sourcing
data sharing
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land: the first days
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
DNA.Land early adopters0
200
0
60
00
10
000
14
000
days
user
s
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
CeCe Mooregenetic genealogist
Carl Zimmerscience writer
Henry Louis Gates, Jr.historian/journalist
AJ Jacobsjournalist/author
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
[email protected] value your feedback!
Richard Aufrichtigsupport specialist
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
facebook.com/knowyourgenome/
Yaniv Erlich 2/3/16 Know Your Genome: Democratize Health @dl1dl1
feedback reciprocity
genealogy
crowd sourcing
data sharing