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1 DNA REPLICATION September 17, 2018 Dr. C. James Ingles University of Toronto [email protected] Reference texts: Berg et al, Chapter 28 Weaver, 5 th ed Chapters 20, 21

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1

DNA REPLICATION

September 17, 2018

Dr. C. James Ingles University of Toronto

[email protected]

Reference texts: Berg et al, Chapter 28 Weaver, 5th ed Chapters 20, 21

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In their 1953 paper in NATURE, Watson and Crick wrote “It has not escaped our notice that the specific base pairing we have proposed immediately suggests a possible copying mechanism for the genetic material.”

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The “end replication” problem