dna damage regulates alternative splicing through inhibition of rna polymerase ii elongation manuel...

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DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto, Manuel de la Mata, Federico Pelisch, Stéphanie Boireau, Kira Glover-Cutter, Claudia Ben-Dov, Matías Blaustein, Juan J. Lozano, Gregory Bird, David Bentley, Edouard Bertrand, Alberto R. Kornblihtt Cell Volume 137, Issue 4, Pages 708-720 (May 2009) DOI: 10.1016/j.cell.2009.03.010 Copyright © 2009 Elsevier Inc. Terms and Conditions

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Page 1: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation 

Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto, Manuel de la Mata, Federico Pelisch, Stéphanie Boireau, Kira Glover-Cutter, Claudia Ben-Dov, Matías Blaustein, Juan J. Lozano, Gregory Bird, David Bentley, Edouard Bertrand, Alberto R.

Kornblihtt 

Cell Volume 137, Issue 4, Pages 708-720 (May 2009)

DOI: 10.1016/j.cell.2009.03.010

Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 2: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 1

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 3: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 2

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 4: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 3

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 5: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 4

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 6: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 5

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 7: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 6

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions

Page 8: DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation Manuel J. Muñoz, M. Soledad Pérez Santangelo, Maria P. Paronetto,

Figure 7

Cell 2009 137, 708-720DOI: (10.1016/j.cell.2009.03.010) Copyright © 2009 Elsevier Inc. Terms and Conditions