digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio...

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Internal medicine Lectures for students, 7 th semester Digestive diseases of ruminants IV. Abomasal diseases Dr. Vörös Károly Belgyógyászati Tanszék és Klinika

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Page 1: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Internal medicineLectures for students, 7th semester

Digestive diseases of ruminants IV.Abomasal diseases

Dr. Vörös KárolyBelgyógyászati Tanszék és Klinika

Page 2: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Diseases of the abomasum

Abomasal displacement Abomasal Abomasal obturation(dislocatio abomasi) (obturatio abomasi)

DA inflammation ulcer(abomasitis) (ulcus abomasi)

left sided right sided(sinistra) ( dextra)

torsion(cum torsione)

reflux syndrome(regurgitatio ingestae abomasi)

Page 3: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Pathogenesis of abomasal displacement

Nutritional abnormality (++ grain, -- fiber)

Abomasal atony

Abomasal dilatation

Anatomical factors Mechanical factors

LDA RDA Abomasal torsion

accompanying dis. hypochloremia accumulation of fluidlocal complications hypokalemia within the abomasumreflux syndrome metab. alkalosis ischemia (necrosis)

+dehydration, (--) tissue perfusionhemoconcentration (++) lactate

metabolic acidosis

Other abomasal disord.Intercurrent diseases(endotoxins)

Fetus,move-ments

Page 4: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Topography of the bovine abdominal

organs (Gyarmati 1954)

Page 5: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Location of the abomasum

normal situation LDAdigvideo7

Page 6: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of LDA I.

Occurence:mainly post partum within some days/weeks

Course:

subacute, chronic (often masked by intercurrent diseases)

General symptoms:

“only” depression, weight loss, (--) milk production

Basic clinical values:

T: n, P: n, R: n /(--) (shallow)(--) rumen movements

Page 7: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Digestive symptoms:

(--), variable appetite, decreased ruminationthin-pasty feces+/- positive reticular pain probes

rumen: small, firm, decreased motility

abomasum: severe LDA: visible, palpable• percussion: oval, tympanic region• auscultation: spontaneous tinkling sounds (30- 40 % )

(bubbling sounds)• auscultation with ballotment: splashing sounds (50-60 %)• auscultation with percussion: metallic sounds (90-95%)

(steel band effect)

Clinical signs of LDA II.

Page 8: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Degrees of LDA

Page 9: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of LDA Spontaneous tinkling sounds

Page 10: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of LDA

Auscultation with ballotment:

splashing sounds

Page 11: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of LDA

Auscultation with percussion:

metallic sounds

(steel band effect)

Page 12: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of LDA III.

Rectal examination: abomasum is not to be palpated (1:100 )medially displaced rumen

Signs of intercurrent diseases:mastitis, foot diseases, puerperal disorders

Symptoms of joint diseases and complications:secondary ketosis, fat mobilisation syndrome, reflux syndrome

Laboratory examinations:blood: (++) PCV, (--) Cl , (--) K, metab. alkalosis, (++) glucose, ketone in milk, urine

Page 13: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Diagnostic work-up of LDA

DiagnosisMost important is the targeted examination of the abomasum !!!

(The finding can change ! Screening examination !)

Differential diagnosisA) diseases with anorexia and ruminal stasis

B) intercurrent diseases, joint diseases, complications

C) diseases with similar finding of auscultation + percussion (differentiation: localisation, probing, puncture )

D) other abomasal diseases

Page 14: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Differential diagnosis of LDA during simultaneous auscultation and percussion

After Rebhun, 1991

Left sided abomasal displacementFree gas + fluid within the rumen(posterior funct. stenosis, acidosis)Pneumoperitoneum

Page 15: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of LDA I.(Utrecht method)

Page 16: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of LDA II.(Utrecht method)

Page 17: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of LDA III.(Utrecht method)

Page 18: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of LDA IV.(Utrecht method)

Page 19: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Videos

Surgical treatment of LDA V.(Utrecht method)

digvideo7

Page 20: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of LDA.(Hannover method)

Page 21: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Development of right sided abomasal displacement and abomasal torsion

RDA Abomasal torsion

Page 22: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of RDA and abomasal torsion I.

Course: acute, subacute

General symptoms:

• after calving, within a few weeks• more severe, than those of the LDA; especially with torsion• serious deterioration, weakness, +/- good body condition• (moderate) abdominal pain

basic clinical values:T: n /(--), P: ++, R: variable

Page 23: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Skin:dehydration (+ sunken eyes)

Mucous membranes:

dry, pale, dirty redCRT: prolonged

Circulatory organs:

signs of peripheral circulatory failure

Clinical signs of RDA and abomasal torsion II.

Page 24: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Digestive organs:

complete inappetence, (++) thirstfeces: scant, pasty, +/- olive greencomplete ruminal stasis, +/- pozitive reticular pain probes(--) liver dullness

Abomasum: •visible and palpable in severe cases•percussion: tympanic oval region, horizontal dullness (pain)•auscultation: spontaneous tinkling/bubbling sounds (20 %)•auscultation with ballotment: splashing sounds (60-70 %)•Auscultation with percussion: metallic sounds (90%)

Clinical signs of RDA and abomasal torsion III.

Page 25: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Rectal examination:balloon-like, palpable abomasum(RDA: 60 %, + torsion: 90 %)firm rumen

Laboratory examinations:(++) PCV, (--) Cl , (--) Kmetabolic alkalosis acidosisleuko/neutropenia

Course:RDA torsion shock death

Clinical signs of RDA and abomasal torsion IV.

Page 26: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of RDA and abomasal torsionAuscultation with percussion: metallic sounds

Page 27: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Diagnostic work-up of RDA and abomasal torsion

Course: rapid

Diagnosis:based on the targeted examination

of the abomasum (including rectal finding !)

Differential diagnosis:

A) Diseases with similar auscultation + percussion(cecal torsion, small intestinal ileus, intestinal atony )

B) Diseases with abdominal pain

Page 28: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

after Rebhun, 1991

Differential diagnosis ofRDA

during simultaneousauscultation and

percussion

Right sided abomasal displacement

Cecal dilatation and torsionSmall intestinal ileus

Page 29: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Differential diagnosis of RDA II. Cecal dilatation and torsion

Page 30: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Differential diagnosis of RDA III.Ileus

Page 31: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of RDA I.

Page 32: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment of RDA II.

Page 33: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Fluid therapy using continuous drip infusion technique

The basics of fluid therapy and the rate of dehydration see at acute

rumen acidosis

Page 34: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

A calf can also have an abomasal displacement and even the veterinarian can suffer from an accident.

Instead of the final word:

Page 35: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Abomasitis and abomasal ulcer(abomasitis, ulcus abomasi)

Forms: Primary Secondary

Occurence: rare more common

Cause:

stress other abomasal disease

grass, fertilizers, leukosis, GI helminths

herbicides VD, salmonellosis

calves: rough fodderfungi, hair balls

Page 36: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs:

Mild form:no symptoms / mild general symptoms, inappetence

Sever form: (bleeding ulcer)anaemia, dehydration, peripheral circulatory failuremelenarumen stasis, positive reticular pain probesabomasum:

pain during pressure (palpation)gas and fluid accumulationabomasocentesis: typical finding

Perforation:localised /diffuse peritonitisrapid death

Abomasitis and abomasal ulcer

Page 37: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Abomasitis and abomasal ulcer in

cattle

Page 38: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Diagnostic work-up:

Diagnosis: feces, local findings, abomasocentesis !

Differential diagnosis:other abomasal diseases, acute enteritisdiseases with acute blood-loosing anemia

Treatment:• diet, adstringents, mucoprotective drugs• blood transfusion, • H2 receptor blocking drugs? (e.g.. cimetidine)• alkalisers (MgO, Mg silicate) • surgery

Abomasitis and abomasal ulcer

Page 39: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Abomasal obturationEtiology:

sand or rough, hard fodder + lack of drinking water(feedlot bulls, sheep)

Clinical signs:similar to abomasal ulcer, but other, characteristic local signs:

abomasum: firm, sand sack-like palpatory finding

Treatment: A) conservative: spasmolytics, laxatives

+ fluid and electrolyte replacement

B) surgery: rumenotomy or abomasotomy

Page 40: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Surgical treatment ofabomasal obturation

(sand obturation)

Page 41: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Pathogenesis of reflux syndromeAbomasal disorder

Back flow of the abomasal fluid

Rumen fluid Blood

(++) acidity by titration metabolic alkalosis(--) pH Cl- < 95 mmol/lCl- > 30 mmol/l hypokalemia(++) osmolality (++) PCV

Sequels

thin (watery) rumen fluid dehydration, (--) GFR

dilatation of the rumen extrarenal uremia

Dirksen, 1984 nyomán

Page 42: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Clinical signs of of reflux syndromeAccumulation of abomasal fluid within the rumen

Dehydration Metabolic Rumen distensionalkalosis

Exsiccosis Uremia Respiration: (++) undulating rumen

skin, urine-like (--) resp. rate thin, sour-smellingeyes, breath, shallow breathing ruminal contentCRT, PCV (++) creatinine

+Characteristic clinical signs of the underlying abomasal disease

DA, abomasitis, abomasal ulcer, obturation, posterior functional stenosis

Page 43: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Reflux syndrome in a cow

Hoflund syndrome, posterior functional stenosis

Page 44: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Study of the compensation of metabolic alkalosiswith pneumotachography

Healthy cow

LDA + reflux syndrome

Page 45: digrum 4 1 abomasum-2005(sinistra) ( dextra) torsion (cum torsione) reflux syndrome (regurgitatio ingestae abomasi) Pathogenesis of abomasaldisplacement Nutritionalabnormality(++ grain,

Thank you for your attention.