DIABETIC COMPLICATIONS. COMPLICATIONS COMPLICATIONS.

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  • DIABETIC COMPLICATIONS

  • COMPLICATIONS

  • COMPLICATIONS

  • COMPLICATIONS

  • COMPLICATIONS

  • CVD Risk Factors:

    Smoking - promotes atherosclerosis Sedentary lifestyle bawal ang tamad !!!Family historyAbdominal obesity esp. central obesityHypertensionDysglycemiaDsylipidemia

  • How to reduce cholesterol level ?Non pharmacologicPharmacologicTreatment goals

  • How to reduce cholesterol level ?Non pharmacologic - diet bawal ang apat na paa !! - exercise more than 30 minutes, more than 3x a week

  • How to reduce cholesterol level ?Treatment Goals: total cholesterol less 160 triglycerides less 100 LDL less 70 (high risk) HDL >45 (male) >55 (female)

  • How to reduce BP ?Non pharmacologicPharmacologicTreatment goals

  • How to reduce BP ?Non pharmacologic lifestyle modification: - low fat , low salt diet - limited alcohol use - regular physical exercise - smoking cessation

  • How to reduce BP ?Treatment Goal: BP should be less 120/80 pre-hpn 120/80 stage I 140/90 stage II 160/100

  • UTAK (CEREBROVASCULAR)

  • PUSO (CARDIOVASCULAR)

  • NGIPIN (PERIODONTAL)

  • MATA (RETINOPATHY)

  • BATO (NEPHROPATHY)

  • UGAT (NEUROPATHY)

  • PAA (PERIPHERAL ARTERIAL)

  • MATA(RETINOPATHY)pangunahing dahilan ng pagkabulagType 1 diabetes= lahat may retinopathy pagkatapos ng 10 taonType 2 diabetes= >60% may retinopathy pagkatapos ng 10 taon

  • maaari ring ito ang unang simtomas sa diabeteskaramihan din sa mga diabetiko ay may retinopathy na sa panahong nalaman na sila ay may diabetes mas malala ang retinopathy sa mga type 1 na diabetiko

  • mga simtomaspanlalabo ng paninginpagdilim ng paninginpagdoble ng paninginitim na spots sa paningin

  • mga risk factorshindi kontroladong asukalhindi kontroladong blood pressuremataas na mantika ng dugo

  • pangangalaga ng mataGawing regular ang pagmomonitor sa asukal sa dugoMagplano ng tamang pagkainMagpatingin sa ophthalmologist minsan sa isang taon o mas madalas pa depende sa mungkahi ng doktorPanatilihing normal ang presyon ng dugo

  • gamotLASER THERAPY

    IBA PANG EXPERIMENTAL NA GAMOT

  • SAKIT SA PUSO

  • STROKE

  • THE ARTERIAL WALL

  • ATHEROSCLEROSIS(paninigas ng ugat)

  • MGA SANHI NG PANINIGAS NG UGAT

  • ANO ANG DAPAT GAWIN PARA MAIWASAN ANG SAKIT SA PUSO & STROKE?Iwasan ang:sobrang pag-inom ng alakpaninigarilyomatakaw sa maalat, matamis o matataba na pagkainSobrang timbang (overweight)Regular na exercise

  • ANO ANG DAPAT GAWIN PARA MAIWASAN ANG SAKIT SA PUSO & STROKE?Regular check-up sa doktor Altapresyon
  • ANO ANG DAPAT GAWIN PARA MAIWASAN ANG SAKIT SA PUSO & STROKE?Regular check-up sa doktor Laboratory examination:Total cholesterol - 50 mg/dlTriglyceride - < 150 mg/dlHbA1c - < 6%ECG

  • DIABETIC NEPHROPATHY(Komplikasyon sa bato)

  • ANO ANG DIABETIC NEPHROPATHY

    Isang kondisyong unti-unting pagkasira ng bato dahil sa epekto ng diabetes

  • ANO ANG NANGYAYARI SA KIDNEYS PAG MAY DIABETIC NEPHROPATHY

    Glomerular Hypertension kauna-unahang pagbaba- gong abnormal sa kidneysProtina sa ihi a. Microalbuminuria b. macroalbuminuria

  • ANO ANG NANGYAYARI SA KIDNEYS PAG MAY DIABETIC NEPHROPATHY

    End Stage renal disease ( Tuluyang pag kasira ng kidneys) ay nang yayari 5-10 yrs matapos madiskubre ang komplikasyong ito.

  • PANO MALALAMAN KUNG MAY DIABETIC NEPHROPATHYMicral testNormal o pagiging malaki ng sukat ng kidneys sa UltrasoundAnemia

  • MGA SANHI NG PAGKAKAROON NG DIABETIC NEPHROPATHY

    Hyperglycemia - mataas na asukal sa dugoHypertension o High blood pressureProteinuria o Protina sa ihiPaninigarilyo Hyperlipidemia o mataas na kolesterol

  • PAANO MAGAGAMOT O MAIIWASAN ANG DIABETIC NEPHROPATHY

    Control ng blood sugarControl ng blood pressureDialysisKidney transplant

    The normal artery has three distinct layers: the intima is the innermost layer and is composed of a single layer of endothelial cells on the luminal surface; the media is a tube of vascular smooth muscle cells (VSMCs) and their extracellular matrix; and the adventitia, the outer protective layer, is made of loose connective tissue that holds the blood vessels and nerves that supply the artery itself.1The endothelial cells of the intima have a number of important functions: forming a nonthrombotic, nonadherent surface; acting as a semipermeable membrane; synthesizing and releasing chemical mediators; maintaining the basement membrane; and modifying lipoproteins as they cross into the artery wall.2The VSMCs of the media contract and relax to alter the lumen diameter of the vessel in response to a variety of circulating and local stimuli, regulating vascular tone, blood flow, and blood pressure. This is caused by the production of a number of vasoactive substances, including prostaglandins, endothelin, and nitric oxide (NO).1As the next slides reveal, LDL cholesterol is a central culprit in disrupting the normal homeostasis of the artery and its lumen, setting the stage for vascular occlusion, ischemia, and infarction.

    References Weissberg PL. Atherosclerosis involves more than just lipids: Plaque dynamics. Eur Heart J. 1999;1(suppl T):T13-T18. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature. 1993;362:801-809.

    The normal artery has three distinct layers: the intima is the innermost layer and is composed of a single layer of endothelial cells on the luminal surface; the media is a tube of vascular smooth muscle cells (VSMCs) and their extracellular matrix; and the adventitia, the outer protective layer, is made of loose connective tissue that holds the blood vessels and nerves that supply the artery itself.1The endothelial cells of the intima have a number of important functions: forming a nonthrombotic, nonadherent surface; acting as a semipermeable membrane; synthesizing and releasing chemical mediators; maintaining the basement membrane; and modifying lipoproteins as they cross into the artery wall.2The VSMCs of the media contract and relax to alter the lumen diameter of the vessel in response to a variety of circulating and local stimuli, regulating vascular tone, blood flow, and blood pressure. This is caused by the production of a number of vasoactive substances, including prostaglandins, endothelin, and nitric oxide (NO).1As the next slides reveal, LDL cholesterol is a central culprit in disrupting the normal homeostasis of the artery and its lumen, setting the stage for vascular occlusion, ischemia, and infarction.

    References Weissberg PL. Atherosclerosis involves more than just lipids: Plaque dynamics. Eur Heart J. 1999;1(suppl T):T13-T18. Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature. 1993;362:801-809.

    Figure 3Traditional risk factors include age, male sex, dyslipidemia, hypertension, smoking, and diabetes. More recently identified risk factors include obesity and a sedentary lifestyle.