di-boc & di-boc derivatives
TRANSCRIPT
MinAscent Technologies GmbHAm Haupttor 4208 D-06237 Leuna GermanyT + 49 3461 43 45 35 [email protected]
Pittsburgh (PA), USAYour scale up partner
Minascent Technologies, Pennakem and Pressure Chemicals are a part of the
Niche Technologies within the Minafin Group.
Memphis (TN), USAOur green arm, Chemicals from renewable sources
Leuna, DEUChallenging ChemistrySmall & Large scalemanufacturing
Pittsburgh (PA), USA
Memphis (TN), USA
USAUSA
BELBEL
FRA
DEU
Dunkerque, FRA
Beuvry, FRA
Leuna, DEU
Louvain-la-Neuve, BEL
EU cGMP API sites
MINASCENT_171016_dina4_v2.indd 4 17.10.17 15:46
MinaSCEnT your Partner of Choice For Challenging ChemistryMinascent has developed worldwide recognition for custom synthesis, contract manufacturing and new product development.
Minascent specializes in challenging organic synthesis, supplyingcustomers in high value-added products with critical quality standards and sophisticated quality systems.
Minascent serves markets including pharmaceuticals, feed additives, cosmetics, flavors & fragrances and specialty chemicals.
MINASCENT_171016_dina4_v2.indd 1 17.10.17 15:47
MinaSCEnT your Partner of Choice For Challenging ChemistryMinascent has developed worldwide recognition for custom synthesis, contract manufacturing and new product development.
Minascent specializes in challenging organic synthesis, supplyingcustomers in high value-added products with critical quality standards and sophisticated quality systems.
Minascent serves markets including pharmaceuticals, feed additives, cosmetics, flavors & fragrances and specialty chemicals.
MINASCENT_171016_dina4_v2.indd 1 17.10.17 15:47
MINASCENT REACTIONS & REAGENTS
AlkylationsAllene chemistryAmidationsChlorinationsCondensationsCyclizationsDi-BOC synthesisDi-BOC protectionsDecarboxylationsHydrazine chemistryHydride reductionHydrogenations (batch)Mannich reactionsOxidationsRearrangementsReductive AminationSelenium chemistrySubstitution electrophilicSubstitution nucleophilicSulphur chemistry
Reactions
Acetylene (currently pilot scale) Acyl chlorides, anhydrides, sulfonyl chloridesAlkynesAcrylamideAlkoxidesAlleneAmmonia (15 bar)ChloroformatesCyanidesDi-BOCDimethyl sulfateGrignard reagentsHydrazineHydrogen PeroxideIodineMethane sulfonyl chlorideMethyl lithiumRaney-NickelPalladium catalystsParaformaldehydePropane sultone (pilot scale)SeleniumSelenium dioxideSodium borohydrideSodium hydrosulphideSodium methylmercaptideSodium tungstateThionyl chlorideVitride
Reagents
PRODuCT DESCRIPTION STRuCTuRE CAS#
Di-tert-butyl dicarbonate (Di-BOC) & custom-made solutions 24424-99-5
N-Boc-4-piperidone 79099-07-3
N-Boc-D-Serine 6368-20-3
N-Boc-ethylenediamine 57260-73-8
N-Boc-glycine tert-butyl ester 111652-20-1
N-Boc-L-tert-Leucine 62965-35-9
N-Boc-L-Valine 13734-41-3
N-Boc-piperazine 57260-71-6
N-Boc-pyroglutamic acid ethyl ester 144978-12-1
N-Boc-trans-4-Hydroxy-L-Proline 13726-69-7
tert-Butyl carbazate 870-46-2
PRODuCT LIST
Di-Boc & Di-Boc DeRiVatiVes
OOO
O O
NBoc
O
HONH-Boc
COOH
H2NNH-Boc
ONH-Boc
Ot-Bu
NH-Boc
COOH
NN
Boc
H
NBoc
O COOEt
NBoc
COOH
HO
O NH
ONH2
NH-Boc
COOH
PRODuCT DESCRIPTION STRuCTuRE CAS#
1-(1-Naphthyl)ethylamine 42882-31-5
1,3-Propanedithiol 109-80-8
1-Octyn-3-ol 818-72-4
2,4-Dimethylthiophenol 13616-82-5
2,5-Dimethylpyrrole 625-84-3
2-Nitro-1,4-phenylenediamine 5307-14-2
3,4-(Methylenedioxy)phenol 533-31-3
3-Chloropropanesulfonyl chloride 1633-82-5
3-Cyclopentylpropionyl chloride 104-97-2
4-(Dimethylamino)-3-methyl-2-butanone 22104-62-7
4-n-Hexylresorcinol 136-77-6
4-Pentynoic acid ethyl ester 63093-41-4
PRODuCT DESCRIPTION STRuCTuRE CAS#
4-tert-Butylanisole 5396-38-3
Benzylhydrazine dihydrochloride 20570-96-1
Benzyl methyl sulfide 766-92-7
Cyclobutanecarboxylic acid 3721-95-7
1,1-Cyclobutanedicarboxylic acid 5445-51-2
1,1-Cyclobutanedicarboxylic acid diethyl ester 3779-29-1
Cyclopropanecarbonyl chloride 4023-34-1
Formylhydrazine 624-84-0
N,N‘-Diethyl-1,3-bis(acrylamido)-propane 442200-41-1
6-(Dibutylamino)-1,3,5-triazine-2,4-dithiol 29529-99-5
tert-Butyl methyl sulfone 14094-12-3
Thiopivalic acid 55561-02-9
PRODuCT LIST
NH2
SHHS
OH
SH
NH2
H2N NO2
O
O
OH
SO2ClCl
COCl
O
N
HO OH
COOEt
COCl
NN
O O
N N(nBu)2HS
SH
N N
SO2Me
SH
O
NH
O
NNH2 2HCl
H
S
COOH
COOEtCOOEt
ONH2
HNH
COOHCOOH
PRODuCT DESCRIPTION STRuCTuRE CAS#
1-(1-Naphthyl)ethylamine 42882-31-5
1,3-Propanedithiol 109-80-8
1-Octyn-3-ol 818-72-4
2,4-Dimethylthiophenol 13616-82-5
2,5-Dimethylpyrrole 625-84-3
2-Nitro-1,4-phenylenediamine 5307-14-2
3,4-(Methylenedioxy)phenol 533-31-3
3-Chloropropanesulfonyl chloride 1633-82-5
3-Cyclopentylpropionyl chloride 104-97-2
4-(Dimethylamino)-3-methyl-2-butanone 22104-62-7
4-n-Hexylresorcinol 136-77-6
4-Pentynoic acid ethyl ester 63093-41-4
PRODuCT DESCRIPTION STRuCTuRE CAS#
4-tert-Butylanisole 5396-38-3
Benzylhydrazine dihydrochloride 20570-96-1
Benzyl methyl sulfide 766-92-7
Cyclobutanecarboxylic acid 3721-95-7
1,1-Cyclobutanedicarboxylic acid 5445-51-2
1,1-Cyclobutanedicarboxylic acid diethyl ester 3779-29-1
Cyclopropanecarbonyl chloride 4023-34-1
Formylhydrazine 624-84-0
N,N‘-Diethyl-1,3-bis(acrylamido)-propane 442200-41-1
6-(Dibutylamino)-1,3,5-triazine-2,4-dithiol 29529-99-5
tert-Butyl methyl sulfone 14094-12-3
Thiopivalic acid 55561-02-9
PRODuCT LIST
NH2
SHHS
OH
SH
NH2
H2N NO2
O
O
OH
SO2ClCl
COCl
O
N
HO OH
COOEt
COCl
NN
O O
N N(nBu)2HS
SH
N N
SO2Me
SH
O
NH
O
NNH2 2HCl
H
S
COOH
COOEtCOOEt
ONH2
HNH
COOHCOOH
MinAscent Technologies GmbHAm Haupttor 4208 D-06237 Leuna GermanyT + 49 3461 43 45 35 [email protected]
Pittsburgh (PA), USAYour scale up partner
Minascent Technologies, Pennakem and Pressure Chemicals are a part of the
Niche Technologies within the Minafin Group.
Memphis (TN), USAOur green arm, Chemicals from renewable sources
Leuna, DEUChallenging ChemistrySmall & Large scalemanufacturing
Pittsburgh (PA), USA
Memphis (TN), USA
USAUSA
BELBEL
FRA
DEU
Dunkerque, FRA
Beuvry, FRA
Leuna, DEU
Louvain-la-Neuve, BEL
EU cGMP API sites
MINASCENT_171016_dina4_v2.indd 4 17.10.17 15:46
MinaSCEnT your Partner of Choice For Challenging ChemistryMinascent has developed worldwide recognition for custom synthesis, contract manufacturing and new product development.
Minascent specializes in challenging organic synthesis, supplyingcustomers in high value-added products with critical quality standards and sophisticated quality systems.
Minascent serves markets including pharmaceuticals, feed additives, cosmetics, flavors & fragrances and specialty chemicals.
MINASCENT_171016_dina4_v2.indd 1 17.10.17 15:47
MinaSCEnT your Partner of Choice For Challenging ChemistryMinascent has developed worldwide recognition for custom synthesis, contract manufacturing and new product development.
Minascent specializes in challenging organic synthesis, supplyingcustomers in high value-added products with critical quality standards and sophisticated quality systems.
Minascent serves markets including pharmaceuticals, feed additives, cosmetics, flavors & fragrances and specialty chemicals.
MINASCENT_171016_dina4_v2.indd 1 17.10.17 15:47
MINASCENT REACTIONS & REAGENTS
AlkylationsAllene chemistryAmidationsChlorinationsCondensationsCyclizationsDi-BOC synthesisDi-BOC protectionsDecarboxylationsHydrazine chemistryHydride reductionHydrogenations (batch)Mannich reactionsOxidationsRearrangementsReductive AminationSelenium chemistrySubstitution electrophilicSubstitution nucleophilicSulphur chemistry
Reactions
Acetylene (currently pilot scale) Acyl chlorides, anhydrides, sulfonyl chloridesAlkynesAcrylamideAlkoxidesAlleneAmmonia (15 bar)ChloroformatesCyanidesDi-BOCDimethyl sulfateGrignard reagentsHydrazineHydrogen PeroxideIodineMethane sulfonyl chlorideMethyl lithiumRaney-NickelPalladium catalystsParaformaldehydePropane sultone (pilot scale)SeleniumSelenium dioxideSodium borohydrideSodium hydrosulphideSodium methylmercaptideSodium tungstateThionyl chlorideVitride
Reagents
PRODuCT DESCRIPTION STRuCTuRE CAS#
Di-tert-butyl dicarbonate (Di-BOC) & custom-made solutions 24424-99-5
N-Boc-4-piperidone 79099-07-3
N-Boc-D-Serine 6368-20-3
N-Boc-ethylenediamine 57260-73-8
N-Boc-glycine tert-butyl ester 111652-20-1
N-Boc-L-tert-Leucine 62965-35-9
N-Boc-L-Valine 13734-41-3
N-Boc-piperazine 57260-71-6
N-Boc-pyroglutamic acid ethyl ester 144978-12-1
N-Boc-trans-4-Hydroxy-L-Proline 13726-69-7
tert-Butyl carbazate 870-46-2
PRODuCT LIST
Di-Boc & Di-Boc DeRiVatiVes
OOO
O O
NBoc
O
HONH-Boc
COOH
H2NNH-Boc
ONH-Boc
Ot-Bu
NH-Boc
COOH
NN
Boc
H
NBoc
O COOEt
NBoc
COOH
HO
O NH
ONH2
NH-Boc
COOH