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eveloping a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International University, Miami, FL

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Page 1: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse

Chaiyapoj NetsiriRice University, Houston, TX

Khokiat KengskoolFlorida International University, Miami, FL

Page 2: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Agenda

• Background

• Gating System

• Hardware

• Conclusion

Page 3: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Background

Animal MRI scanner Imaging probe

Page 4: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

~250mm

Heart rate: 325-780 beat/minuteRespiratory rate: 94-163 breath/minute

Mouse’s organ imagingMouse’s organ imaging

Mouse

Kidney Liver

Problem: fast movement

~100 times averaging

Page 5: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International
Page 6: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International
Page 7: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International
Page 8: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International
Page 9: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Gating system

ECG cableRespiratorysensor

Page 10: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Results

Liver

Kidney

Page 11: Developing a Cardiac Gating System for Magnetic Resonance Imaging of a mouse Chaiyapoj Netsiri Rice University, Houston, TX Khokiat Kengskool Florida International

Conclusion

• Water-filled balloon and pressure sensor can be used in

• respiratory gating.

• Electronic system is inexpensive and easy to build.

• Double shield system can effectively protect ECG signal from

MRI scanning noise.

• Gating system provides significant improvement of image quality.


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