detectives in the classroom - investigation 2-8: which design is best? which design is best?
TRANSCRIPT
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Which Design
Is Best?
Which Design Is Best?
1How is this disease
distributed?Hypotheses
3Is the association
causal?
4What should be done
to prevent the disease?
5Did the prevention
strategy work?
Where are we and where are we going?
What’s my hypothesis?
2Is there
an association?
Did the exposure and the disease turn up
together?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Time
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Trial
E DZ
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Study Design
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Time
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Cohort Study
E DZ
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Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Study Design
Time
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Case-Control Study
E
DZ-
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Study Design
E
DZ
Time
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Cross-Sectional Study
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Study Design
E DZTrial+++++++++++++++++++++++++++++++++++++++++++++++++++++
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E DZCohort Study+++++++++++++++++++++++++++++++++++++++++++++++++++++
++++++++++++++++++++++++++++++++++++++++++++++++++++++
EDZ
Case-Control Study++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
EDZ
+++++++++++++++++++++++++++ ++++++++++++++++++++++++ +++++++++++++++++++++++++ +++++++++++++++++++++++
Cross-Sectional Study
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4 Study Designs
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
Case-Control Study
Cohort Study
Cross-Sectional Study
Trial
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
2nd
3rd
4thWeaker
Stronger1st
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
2nd
3rd
Longest
Time
Shortest
Time
1st
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Which Design Is Best?
3rd
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
4 Study Designs
2nd
3rd
4th
Most
Expensive
Least
Expensive
1st
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
2nd
3rd
4th
Least
Accurate
Most
Accurate
1st
Trial
Cohort Study
Case-Control Study
Cross-Sectional Study
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
2nd
2nd
2nd
Least
Similar
Most
Similar
1st
Trial
Cohort Study
Case-Control Study
Cross-Sectional Study
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
2nd
3rd
4th
Least
Sound
Most
Sound
1st
Trial
Cohort Study
Case-Control Study
Cross-Sectional Study
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Epi Team Challenge
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Cross-Sectional
CohortCase-
Control Controlled
Trial
Epi Team Challenge
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Which study design is the fastest?
Epi Team Challenge
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Time Consuming
Which study designs are the most time consuming?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Most Scientifically Sound
Which study design is the most scientifically sound?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Most Scientifically Sound
Can Study Rare Diseases
Which study design is best for studying rare diseases?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Most Scientifically Sound
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Which study designs do not identify the time order of exposure and disease?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Which study design gives the least confidence in findings?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Which study design provides the best measure of exposure?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Most Accurate Observational Study
Which study design is the most accurate observational study?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Most Accurate Observational Study
Which study design is the least expensive?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Unethical for Harmful Exposures
Most Accurate Observational Study
Which study design would be unethical for harmful
exposures?
Time Consuming
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Good Measure of Exposure
Which study design provides a good measure of exposure?
Most Accurate Observational Study
Time ConsumingUnethical for Harmful exposures
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Most Expensive
Most Expensive
Most Accurate Observational Study
Which study designs are the most expensive?
Good Measure of Exposure
Time ConsumingUnethical for Harmful exposures
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Relatively Less Expensive and Relatively Fast
Most Accurate Observational Study
Which study design is relatively less expensive and relatively fast?
Time ConsumingUnethical for Harmful exposures
Most Expensive
Most ExpensiveGood Measure of Exposure
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Least Confidence in Findings
Most Scientifically Sound
Best Measure of Exposure
Possible Time-Order Confusion
Possible Time-Order Confusion
Can Study Rare Diseases
Least Expensive
Relatively Less Expensive and Relatively Fast
Possible Error in Recalling Past Exposures
Most Accurate Observational Study
Which study design creates the possibility of error in recalling past exposures?
Time ConsumingUnethical for Harmful exposures
Most Expensive
Most ExpensiveGood Measure of Exposure
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Epi Team Challenge
Cross-Sectional Study
Case-Control Study
Cohort Study
Trial
Main WeaknessesMain StrengthsStudy Designs
1 5
62
3 7
84
Fastest
Time Consuming
Most Scientifically Sound
Best Measure of Exposure
Can Study Rare Diseases
Least Expensive
Relatively Less Expensive and Relatively Fast
Possible Error in Recalling Exposures
Most Accurate Observational Study
Which Design Is Best?
Which Design Is Best?
Time Consuming
Unethical for Harmful exposuresMost Expensive
Most Expensive
Possible Time-Order Confusion
Possible Time-Order Confusion
Least Confidence in Findings
Good Measure of Exposure
It depends ….
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
It depends on ….
• Regulations
• Time urgency
• How much is known about the association
• Money
• Whether the exposure is believed to be beneficial
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
An Example
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
4 Study Designs
Case-Control Study
Cohort Study
Cross-Sectional Study
Trial
Which Design Is Best?
What is your
personal
favorite?
Why? -
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?
Investigation 2-8 has ended.
Which Design Is Best?
Detectives in the Classroom - Investigation 2-8: Which Design Is Best?