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  • 8/14/2019 Cyber Knife Protocol

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    CyberKniferobotic surgerynoninvasive,precise,shorttreatmenttime,automaticallytracksprostate,quickrecovery,minimumpossiblesideeffects

    Noagelimitation Nolimitationduetoothercoexistingdiseases Noprostatesizelimitation PossibleevenwithpriorTURP

    CyberKnifealone(CKmonotherapy)*

    LowGleason 7orless PSA20

    CyberKnifeforQualityofLife

    Localdiseasecontrol Recurrenceaftersurgeryorradiotherapy Symptomaticsitesanywhereinthebody

    HCGCyberKnifeProtocols

    CarcinomaPROSTATE

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    Facts:

    Thereissolidbiologicrationalefortreatingprostatecancerpatientsin5fractions Variousstudiesdemonstrateaconsistent,significantearlyPSAresponsewithamedian18

    monthPSAresultof0.22ng/ml.

    TreatmentrelatedtoxicitytodatehasincludedgradeI IIurinarysymptomsthatnormallyresolvein46weeks,andgrade0 Irectalsymptomsthatnormallyresolvein23weeks.

    Resultsofa3yearstudyin41patientsundergoingCyberKnifetherapyalonebyKingCRetal,fromStanfordUniversity(March2009):

    o Therewereminimalbladderandrectalsideeffectsrespondingoveraperiodoftime.o AbenignPSAbounce(median,0.4ng/mL)wasobservedin12patients(29%)occurring

    at18months(median)aftertreatment.

    o Of32patientswith12monthsminimumfollowup,25patients(78%)achievedaPSAnadir


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