Custom Retrovirus

Production

Presented by Creative Biogene

About Creative Biogene

Creative Biogene provides kits, reagents, and services that help researchers

explore questions about gene discovery, regulation, and function. Creative

Biogene holds a leadership position in the global market and is committed to

improving the human condition through biotechnology.

Introduction

• Retroviruses are negative single-stranded RNA

viruses in which tRNA serves as a primer for

the mRNA synthesis. The mRNA is then

reverse transcribed into DNA, which is then

integrated into the chromosome at a

multiplicity of sites, particularly those that are

transcriptionally active. Retroviral vector-

mediated gene transfer has been central to the

development of gene therapy.

Advantages

• Retroviruses have several distinct advantages

over other vectors:

• transform their single-stranded RNA genome

into a double stranded DNA molecule that

stably integrates into the target cell genome.

Provider

• Creative Biogene is pioneering in the

development of retroviral technology with years

of experience in retroviral services. Creative

Biogene's custom retrovirus production is a

highly efficient approach to deliver genes of

interest for stable expression into a broad range

of dividing mammalian cells and it aims to

provide valuable research tools and services in

molecular biology.

Custom Retrovirus Construction

Services

Construction of ordered retrovirus vector (gene expression and

shRNA expression).

Production of a retrovirus producer cell line by transfection.

Production of viral supernatant by transient transfection as

well as assay for replication competent

retrovirus.

Quality control assays including quantification of genome

copies and quantification of retroviral

vector infectivity.

Contact

Creative Biogene at http://www.creative-

biogene.com/Services/Custom-Viral-

Service/Retrovirus-service.html

Tel: 1-631-626-9181 or 44-207-048-3343

Email: info@creative-biogene.com