CURRICULUM VITAE

DATO DR. NOR SHAHIDAH KHAIRULLAH DPMP JMNMB,BS, MSc, FRCPath, FAMM, WOSAAM, AAAM

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CURRICULUM VITAE

Dato’ Dr Nor Shahidah bt. Khairullah MB,BS ( Mal) , FRCPath (UK), MSc (Lon), FAMM (Mal), AAAM (USA), WOSAAM (EuR),

TERTIARY EDUCATION AND QUALIFICATIONS

1978-1983 : University of Malaya, Faculty of MedicineBachelor of Medicine, Bachelor of Surgery (MB,BS)

1987-1988 : University of London, London School of Hygiene and Tropical Medicine

Master in Science in Clinical Virology (MSc.)

1994 : Membership of Royal College of PathologistsUnited Kingdom (MRCPath)

1997 : Member of Academy of Medicine Malaysia (AM)

2002 : Fellow of Academy of Medicine of Medicine Malaysia (FAMM)

2003 : Fellow of the Royal College of Pathologists United Kingdom (FRCPath)

2009 : Board Certification American Association Aesthetic Medicine (AAAM)

2009 : Board Certification World Society AntiAging Medicine ( WOSAAM Europe)

AWARDS

2007 : Datuk Paduka Mahkota Perak (DPMP)

2006 : Johan Mangku Negara (JMN)

1993-1994 : Petronas Subspecialty Award in London United Kingdom

1990 : British High Commissioner’s Research Award in Oxford United Kingdom

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WORK EXPERIENCE

Current Appointments

July 2013 present : Corporate Director Of Medical Affairs , Villa Medica International. ( Regenerative Medicine ) January 1999- present : Chief Executive Officer & Medical Director, Molecular Research Laboratory, Malaysian Liver Foundation ( Voluntary)

Past Appointments

Corporate

August 2010 –June 2013 : Consultant Physician , Global Doctors Specialist Hospital

April 2008 – June 2013 : Medical Adviser, Ruyi Holdings Sdn Bhd

May 2008-April 2012 : External Medical adviser Sanofi Aventis (M) Sdn Bhd

January 1999- December 2000 : Asia Pacific Infectious Disease Clinical Research Physician For Eli Lilly Pharmaceuticals & Co Asia Pacific

May 1999- December 2000 : External Medical Consultant for Hepatitis and HIV GlaxoWellcome Pharmaceuticals (M) Sdn Bhd April 1998- January 1999 : Medical Director for Malaysia and Singapore Eli Lilly (M) Sdn. Bhd and Eli Lilly Singapore Pte Ltd

Mar 1997 – 1998 : Assoc. Medical Director Specialty Medical Laboratories Sdn Bhd

Academic

January 2013- Jun 2013 : Deputy Vice Chancellor , Research & Innovation , MAHSA University

September 2012 – December 2012 : Dean for Centre for Post Graduate Studies , MAHSA University

1988-February 1997 : Associate Professor/Consultant Virologist Department of Medical Microbiology Faculty of Medicine, University of Malaya

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Overseas appointments

1994 : Senior Registrar/Consultant Heartland Hospital, Birmingham B9 5SS United Kingdom

1993 : Senior Registrar/ Consultant Department of Virology Royal Free Hospital, United Kingdom

PROFFESSIONAL COMMITTEES

1. Scientific Advisory Committee, Drugs for Neglected Diseases Initiative (DNDi Geneva) ( 2005-2012)

2. National Credentialling and Privileging Committee for Aesthetic Medical Practices Ministry of Health (2010-present)

3. National Subcommittee on Education and Training for Aesthetic Medical Practices Ministry of Health ( 2012-present)

4. Board member Society of Advancement of Hormones and Healthy aging Malaysia (SAHAAM) (2009 - 2012)

5. Board member Malaysian Society for Aesthetic Medicine (MSAM) (2010-present)

6. Board member Malaysian Astrological society (MAS) (2009-2012)

7. National Formulary ‘Blue Book “ Committee (2003-2009)

8. National Committee for Research & Development in Herbal Medicine (2002- 2009)

9. Beta Group for Integrated Global Hub in Traditional and Complementary Medicine (2003- 2009)

10. National Scientific and Ethics Committee for Ministry of Health Malaysia (2001-2010)

11. Genetic Modification Advisory Council Malaysia (2003-2011)

12. National Committee for Vector Borne Diseases ( 2001- 2010)

13. ASIAN Regional Coordinator for Global R&D Coalition for TB Research (2001- present)

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14. National Food Safety Committee ( 2002 - 2009)

15. National Committee on Good Laboratory Practice (2001- 2009)

16. Chairman, Infection Control Committee, Ministry Of Health Malaysia (2002-2004)

17. National Committee for Clinical Research Ministry of Health, Malaysia (1999-2010)

18. Steering Committee for the prevention and control of infectious diseases in the Asia Pacific (2001-2009)

19. National Committee on Good Clinical Practice, Ministry of Health Malaysia (1998-2008)

20. Suitability of Hepatitis A vaccines, HAVRIX Paediatric 360 and HAVRIX 1440

for registration in Malaysia : 12th April 1996

21. Ministry of Health, Malaysia Issues in the control of Influenza in Malaysia : 6th December 1995

22. World Health Organisation, Geneva, Switzerland; Global Surveillance of Respiratory viruses-Current status : 25-27th March 1992

23. Ministry of Health, Malaysia; Certification of Polio virus vaccine in Malaysia : 15th June 1992

24. Main Advisory Committee (MAC) University Hospital : 1995-1997

25. Coordinator for WHO Collaborating Centre for the surveillance, diagnosis and control of Influenza in Malaysia (1989-1996)

RESEARCH EXPERIENCE

1) International Clinical Trials

A double-blind parallel group, placebo controlled, multi-centre, phase III A study to assess the safety and efficacy of oral famciclovir (three times a day) for the treatment of chronic hepatitis B in an Asian Population (1996-1998)

A double-blind, double dummy, randomised, multicentre Acyclovir-controlled, parallel group study to compare the safety and efficacy of

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Famciclovir and Acyclovir in treatment of patients with uncomplicated Herpes Zoster (1995-1996)

An open study to determine the efficacy of Lamivudine on HBV DNA clearance and to assess the safety of the regimen in Asian patients with chronic hepatitis B infection (1998-1999)

An open label study assessing the efficacy and safety of different formulations of cefaclor in the treatment secondary bacterial infections in acute and chronic bronchitis among patients in the Asia Pacific region (1999-2000)

A randomized double blind placebo controlled study of oral Lobucavir in subjects chronically infected with hepatitis B virus who have failed or are intolerant to alpha-interferon therapy (1998-2000)

A double blind placebo controlled clinical endpoints trial of Lamivudine in patients with hepatitis B related cirrhosis (1998-2003)

A randomized double blind placebo controlled study of Adefovir Dipivoxil for the treatment of patients with HBeAg positive CHB infection (1999-2001)

A phase 11 study of the safety and antiviral activity of Entecavir (BMS-200475) vs Lamivudine in adults with CHB (1992-2000)

A phase 11 study comparing the safety and antiviral activity of Therapeutic Hepatitis B vaccine (Pharmacine) plus Lamivudine vs Lamivudine alone in adults with CHB (2000-2002)

2) Basic Research

Innovative approaches for diagnosis and management of dengue virus infections

Molecular characterization of a Malaysian Nipah virus isolate

Research & Development and production of viral infectious clones with special emphasis on SARS coronavirus, dengue virus and hepatitis C virus

Seroepidemiology study of MMR in Malaysia

Incidence and molecular epidemiology of Japanese Encephalitis (JE) In Malaysia

To study the clinical and virological prognostic factors of different enteroviruses involved in HFMD in Malaysia

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The use of recombinant proteins and synthetic peptides for diagnosis and the elucidation of virulence markers in dengue virus infection

Rapid diagnosis of Human cytomegalovirus in the management of immunocompromised patients.

Characterisation of Malaysian Dengue Viruses

Development of rapid diagnosis for cytomegalovirus

Development and evaluation of rapid diagnostic methods for detection of respiratory viruses

Technical and Experimental Skills

Traditional Culture and Detection Methods

Viral cell culture, Plaque assays, Neutralisation assay, Enzyme linked Immunosorbent Assay (ELISAs), Flourescent antibody assays, Haemagglutination assays, Complement Fixation assay, Electron microscopy

Molecular Biology ( Nucleic acids and proteins )

RNA and DNA extraction methods, Southern, Northern and Western Blotting using radioactive and non radioactive labels,Polymerase Chain Reaction, Branched Chain DNA cDNA synthesis, DNA and RNA sequencing, Baculovirus expression and Vaccinia virus expression of viral genes, Radio-immunoprecipitation, Synthetic peptide synthesis (FMOC), Restriction Enzyme analysis, In situ hybridisation assay, Real time PCR.

3. Supervisory Experience

a) Masters of Medical Science

1. Expression of a Carboxy-Terminally truncated envelope protein of a Malaysian dengue-3 virus in insect cells by a recombinant baculovirus (1995-1997)

2. Molecular Characterisation of Malaysian dengue viruses (1996-1999)

3. Molecular Characterisation of Malaysian dengue 3-viruses (1996 – 1999)

b) Master of Pathology - Virology 7

An evaluation of a commercial dengue Ig M capture ELISA kit(1995-1996)

c) Diploma of Advanced Certificate in Medical Laboratory Technology

a) The use of shell vial assay in the isolation of viruses in clinical specimens (1992)

b) Comparative evaluation of two methods for the diagnosis of Rotavirus infection (1992)

c) Dot immunobinding assay for the diagnosis of Japanese Encephalitis infection in Malaysia (1991)

d) BSc. Biomedical Science

Comparative evaluation of two primers in the diagnosis of Human cytomegalovirus using the polymerase chain reaction (1996)

c) BSc. (Hons) Biochemistry

The role of HCMV as a risk factor in the development of atherosclerosis in a selected Population (1996)

B. Workshops Organised

1) Liver Update Meetings since 1997 till todate

2) Good Clinical Practice (GCP) - an introduction 1998 3) The Application of Amplification Methods in Viral Hepatitis 2000

4) Mentoring Workshop 2013

C. Evaluation Activities

University Level

Examiner for the following thesis :

Master of Philosophy ( PhD) Masters of Medical Science Diploma of Advanced Certificate in Medical Laboratory Technology Evaluation of research proposals submitted for postgraduates

degrees8

Master of Medical Science

a) Molecular and Cellular Biology of Dengue virus 1995

b) Molecular Biology of Dengue viruses 1995

c) Molecular Immunology of Dengue viruses 1995

d) Molecular Characterisation of Helicobacter pylori strains 1995

PhDa) Molecular Studies of Rickettsial Infections 1995

b) Molecular characterization of Nipah Viruses 2002

Editorial Work

1) Editor- Liver News 1998 - present Official Newsletter of The Malaysian Liver Foundation (3 issues a year)

2) Editor : Journal of the Malaysian Astrological Society (2009- present )3) Editor- Infection and Chemotherapy 1997- 2000

Official Newsletter of The Malaysian Society of Infectious Diseases And Chemotherapy

3) Reviewer- MIMS MEDEX 1998 (Malaysia)Manuscript entitled : Designing Pathology Laboratories

4) Editor - Journal of University Malaya Medical Centre (JUMMEC) (1996-1997)

5) International Reviewer - Journal of Medical Virology (1995)Manuscript entitled : Detection of dengue-2 sense, antisense,

replicative intermediate and replicative form RNA in Aedes psuedoscutellaris (AP 61) and baby hampster kidney (BHK-21) cells

6) Reviewer - Journal of Tropical Biomedicine (1990)

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Manuscript entitled : Experimental infection of Macaca fascicularis and Presbytis cristada with SA11 Group A Rotavirus

D. Past Administrative Duties

a) University level

Fellow of 3rd Residential College, University of Malaya Coordinator for Virus positive reports sent monthly to centres within

Malaysia and Western Pacific Basin

b) Faculty

1. Internal examiner for the following courses:

Master of PathologyStage 2 MB,BS (Medical)Year 2 BDS (Dental)

School of Nursing-Both the basic and the advance courseYear 3 and Biomedical SciencesBachelor of Science (Hons) PharmacyDiploma in Advanced Certificate in Medical Laboratory TechnologyCoordinator for Virology Examination (Theory and Practical) for the above

courses

2. Pioneer member of Editorial Board of Faculty of Medicine’s Journal (JUMMEC)

3. Member of the Main Advisory Committee (MAC) of the University Hospital

4. Post graduate (research) Ad-hoc committee

5. Coordinator for the Medical Microbiology course for the Department of Pharmacy

c) Department

1. Curriculum subcommittee2. Translation of examination questions into Bahasa Malaysia and advocating

the use of Bahasa Malaysia in the Medical and Dental teaching

SPEAKING ENGAGEMENTS

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“Healthy Aging and Beauty from the Inside Out “ : Conference of the Indonesian Society of Reversing Aging Society ( July 2012)

Implications of the the Sixth House in Vedic Astrology : International Conference in Astrology and Vasthu , Kathmandu, Nepal ( August 2012)

Hepatitis Vaccines . Liver Update 2011

Conference of the Indonesian Society of Reversing Aging Society ( July 2011)

Singapore General Practitioners Society Meeting (2010)

Conference of the Indonesian Society of Reversing Aging Society ( July 2010)

Herbal Medicine Research – Issues and Challenges. Nuetraceuticals, Complementary Medicine & Wellness Asia 2003 Summit. (August 2003)

Herbal Hepatoxicity- Liver Update 2003

Viral Infections in liver transplant patients –Liver Update 2003

SARS diagnosis in Malaysia -experience of the SARS Reference Laboratory.Mid year seminar of the Malaysian Society of Parasitology and Tropical Medicine (July 2003)

Clinical Research In Malaysia- GCP workshop, International Medical University (July 2003)

Good Laboratory Practice and Good Clinical Practice .GCP workshop , Ministry of Health Malaysia ( July 2003)

Vaccination- Current situation and perspectives. 13 th MIMLS National Scientific Conference ( September 2002)

Hepatitis A outbreaks- a role for immunization. Ministry of Health (April 2002)

Hepatitis Management Programmes in Malaysia. International Congress on Infectious Diseases Singapore ( March 2002)

Hepatitis A in Malaysia. Asia Pacific Steering Committee for the Prevention Of Infectious Diseases, Singapore (November 2001)

Hepatitis A epidemiology in the ASEAN region. Evidence-based Vaccinology ,A Regional Conference ,Kuala Lumpur (June 2001)

GCP and Laboratories- Workshop in Clinical Trials Methodology HUKM (October 2001)

Viral Hepatitis in the ASEAN region . First Asia Pacific Congress of Medical Sciences, Kota Bharu (May 2001)

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Utility of hepatitis virus nucleic acid based diagnostics in therapeutic drug trials.11th Scientific Meeting of the Malaysian Society of Molecular Biology and Biotechnology (May 2001)

Epidemiology and Disease Burden of Viral Hepatitis in Malaysia . National Hepatitis Symposium (November 2000)

Utility of Viral Load Testing in Management of Chronic Viral Hepatitis. National Hepatitis Symposium (November 2000)

. Introduction to ISO 17025 Laboratory Accreditation System. 1st National

Symposium in Good Laboratory Practice (November 2000)

GLP in Molecular Biology -1st National Symposium in Good Laboratory Practice (November 2000)

Principles of ICH GCP- 35th Malaysia –Singapore Congress of Medicine (August 2000)

Malaysian Guidelines on GCP-35th Malaysia –Singapore Congress of Medicine (August 2000)

Malaysian Guidelines On Good Clinical Practice- Workshop in Clinical Trials Methodology HUKM ( September 2000)

GCP and Laboratories- Workshop in Clinical Trials Methodology HUKM (September 2000)

Malaysian Guidelines On Good Clinical Practice – National Workshop in Good Clinical Practice ( August 2000)

Cefaclor in the Millenium- Lilly Lecture Symposium, Bangkok, Thailand ( August 2000)

Vancomycin –An update. The treatment of pneumonia among intravenous drug abusers –a symposium. Army Hospital,Soebroto, Jakarta, Indonesia ( October 1999)

New Antivirals – Infectious disease symposium 33rd Malaysia- Singapore Congress of Medicine ( 1999 )

Management of Chronic Hepatitis B –an update Lecture series coorganised by The Malaysian Liver Foundation and MMA (1998-2000)

Management Of Chronic Hepatitis – Update on AntiviralsWeekend Tutorial in Hepatitis For GPs- Malaysian Liver Foundation (1998)

Epidemiology of Hepatitis B and C and the Link to Hepatocellular Carcinoma Consensus Guidelines on Screening For Hepatocellular Carcinoma, Academy of

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Medicine and Malaysian Society Of Gastroenterology and Hepatology (October 1998)

Diagnosis of Viral Infections-Techniques and Clinical UtilityAnnual Scientific Meeting of The College Of Physicians Malaysia (May 1998)

Polymerase Chain Reaction National Workshop in Clinical & Epidemiological Research Methods Ministry of Health Malaysia (November 1997)

8th National Scientific Conference Of The Malaysian Institute Of Medical Laboratory Sciences (October 1997)

1.Diagnosis Of Mycobacterial Infection: An Update

2.Utility Of Amplification Techniques In Viral Hepatitis

31st Malaysia-Singapore Congress Of Medicine (1997)Universal Precautions Against HIV For The Paediatricians. Techniques And Cost

Benefits

Malaysian Society Of Infectious Disease And Chemotherapy and Ministry of Health (1997)Laboratory Diagnosis Of Viral Infections - Public Forum

Malaysian Society Of Infectious Disease And Chemotherapy and Dewan Bandaraya (1997) - Public Forum on Viral Gastroenteritis

Malaysian Society Of Infectious Disease And Chemotherapy (1996) - Scientific Meeting Respiratory Syncytial Virus

Hospital Kuala Lumpur (1996)Preparatory Course For MRCP Part 1-Infectious Diseases

Petronas Training Centre, Malacca (1995)Hepatitis A Vaccination

19th Annual Scientific Meeting Of The Malaysia Society Of Health (1995)Immunisation In The Prevention Of Virus Associated Cancer

SEAMEO-TROPMED; Diploma In Medical Microbiology (1989-1992)

University Kebangsaan Malaysia (1990)Antiviral Chemotherapy - Weekend Course In Infectious Diseases

Media Personality (RTM 1)

Selamat Pagi Malaysia (1997)Topics : Hepatitis

DiarrhoeaObesity

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InsomniaRashCoughs & Colds

ORGANISING COMMITTEES

Regional and Local Congresses

First Malaysia –Singapore Congress of Aesthetic Medicine (2012)

Liver Update (2011)

First Islamic (OIC) Conference of Ministers of Health (2007)

Second Annual Conference “Self Reliance Programme in Vaccines Among OIC Countries” (2005)

6 Liver Update International Conference (2005)

5 Asia Pacific Travel Health Conference (2004)

International Conference in Traditional and Complementary Medicine (2003)

Liver Update ( 2002-2003)

4th Asia Pacific Conference in Travel Health (2002)

6th International Forum on Global Vaccinology ( 2002-2003)

First National Life Sciences Conference- Genomics and Health ( May 2002)

Evidence-based Vaccinology Symposium (June 2001)

Asia Pacific Clinical Trial Conference (2000-2001)

National Symposium on Good Laboratory Practice (2000)

National Hepatitis Symposium (2000)

Liver Update 2001 (2000-2001)

Liver Update 99 (1998-1999)

33rd Malaysia-Singapore Congress of Medicine (1998 - 1999)

Liver Update 97 (1996-1997)

6th Western Pacific Congress of Infectious Disease and Chemotherapy WESPAC:(1995-1998)

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University of Malaya Women’s Association : Seminar on Women and Health (1991)

7th International meeting of the International Union of Venereal Diseases and Treponematoses (1990)

MEMBERSHIP IN ACADEMIC AND PROFESSIONAL ASSOCIATIONS

1) Pasti. Academic Staff Association of the University of Malayaii. Alumni of the University of Malayaiii. Academic Staff Association of Faculty of Medicine - Treasureriv. Malaysian Association of Private Medical Laboratories - Vice Presidentv. Malaysian Society of Molecular and Cellular Biologyvi. Malaysian Society of Infectious Disease and Chemotherapy ( 1998- 2000)

Committee membervi. Pacific Basin Respiratory Virus Research Group - Editorial Board membervii. American Society for the Advancement of Science

2) Presenti. Malaysian Liver Foundation (1997-) Research Chairman and Scientific Advisory Committeeiii. Malaysian Society of Travel Medicine ( President 2002 - 2004)iv Asia Pacific Travel Health Society (2003- 2006)– President

SUBMITTED VARIOUS PUBLICATIONS AND RESEARCH REPORTS

PUBLICATIONS

1. Fuxun Yu, Nor Shahidah Khairullah et al. (2006).Serodiagnosis using recombinant Nipah Virus nucleocapsid protein expressed in E coli .J Clin Microb; 44 (9) :3134-3138

2. Nor Shahidah Khairullah, Ismail Merican.Chronic Hepatitis B and Herbal Therapy. Medical J Malaysia (2005); Suppl B:35-38

3. Nor Shahidah Khairullah .Hepatitis A vaccines Medical J Malaysia (2005); Suppl B:112-15

4. Nor Shahidah Khairullah, Ismail Merican.Hepatitis Management Programmes in Malaysia .J Gastroenterol Hepatol 2004;19 Suppl :S13-16

5. TS Saraswathy,Nor Shahidah Khairullah et al.(2004)Laboratory Acute Flaccid Paralysis Surveillance in Malaysia: A decade of Commitment to the WHO Global Polio

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Eradication Initiative.Southeast Asian J Trop Med Public Health:35(2):421-424

6. Nor Shahidah ,Ismail Merican and Raman Ismail (2003).Influenza Surveillance in Malaysia :1997-2001.Malysian J Public Health Medicine;3(1):11-15

7. Nor Shahidah Khairullah. Herbal Hepatotoxicity Medical J Malaysia (2003) 58; Supple B: 66-74

8. A Padmanathan, NS Khairullah and I Merican . Determination of HBV Polymerase Gene Mutations in Chronic hepatitis B Patients Medical J Malaysia(2003) 58; Supple B: 84

9. Y Roziyah, NS Khairullah and I Merican (2003). Distribution of Hepatitis C genotypes in Malaysia. Medical J Malaysia ; Suppl B:108

10. Nor Shahidah Khairullah. Other viral infections in liver transplant patients.Medical J Malaysia (2003) Med J Malaysia 58; Suppl B:77

11. A Padmanathan ,NS Khairullah and I Merican .Prevalence of hepatitis B Genotypes in Malaysia (2003) Medical J Malaysia; 58 Supple B: 83

12. N Khairullah and I Merican et al. (2002)Age specific seroprevalence of hepatitis A virus infection in Malaysia- a changing pattern. Asian-Oceanian J Paediatrics & Child Health;1 (2):137-145

13. Nor Shahidah Khairullah. Travel Medicine in Malaysia- a Country Report. 4th AsiaPacific Travel Health Conference (2002):119

14. NS Khairullah, V Subramaniam, LK The,N Shamsiah. Nipah virus Encephalitis.4th AsiaPacific Travel Health Conference (2002):115

15. Nor Shahidah Khairullah.Vaccination, Current Situation and Perspective.13th National Scientific Conference of the Malaysian Institute of Medical Laboratory Sciences(2002):19

16. LY Lim,Vijayamalar B, NS Khairullah. Laboratory Diagnosis of HIV in Infants.5th Scientific Meeting of the Institutes of Health , Ministry of Health Malaysia(2002):49

17. R Thayan, F Sonkerim, V Subramaniam ,NS Khairullah. Virological Surveillance of Dengue Serotypes. 5th Scientific

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Meeting of the Institutes of Health , Ministry of Health Malaysia(2002):50

18. TS Saraswathy,NS Khairullah,F kassim,MA Yusof,MS Mohd Zain.Laboratory AFP Surveillance in Malaysia:A decade of commitment to the WHO Global Polio Eradication Programme. 5th Scientific Meeting of the Institutes of Health , Ministry of Health Malaysia(2002):47

19. NS Khairullah et al. Dengue virus infection in Malaysia. International Congress of Infectious Diseases, Singapore (2002):32

20. V Balasubramaniam, NS Khairullah et al. Persistance of Nipah virus IgG and IgM in asymptomatic and post nipah encephalitis patients. International Congress of Infectious Diseases, Singapore ( 2002):87

21. CC Roa, NS Khairullah and PA Punzal et al. The Clinical Efficacy of Cefaclor in the Treatment of Secondary Bacterial Infection in Bronchitis.(2001).Supplement to Medical Progress:28:5:5-12

22. Nor Shahidah Khairullah. Viral Load Assays (2001).Supplement to Medical Progress.:28:7;101-104

23. A.Pathmanathan, NS Khairullah ,I Merican. Validation of the ICT Rapid Assay for the dual Detection of Hepatitis B Surface and HBeAg (2001).Liver Update 2001”Lessons from the Past,issues for the Future”;9-15 July:36

24. Roziyah Yusup, Nor Shahidah Khairullah, Ahila Pathmanathan, Ismail Merican (2001).Hepatitis C virus genotypes in Malaysia.Supplement to Medical Progress,28:7:121-123

25. Ahila Pathmanathan,Nor Shahidah Khairullah,Ismail Merican(2001). Seroprevalence of HBsAg and HBsAb among children in Johore. Supplement to Medical Progress:28:7:124-127

26. Nor Shahidah Khairullah (2001). Utility of hepatitis virus nucleic acid based diagnostics in therapeutic drug trials.11th Scientific Meeting of the Malaysian Society of Molecular Biology and Biotechnology ;pg 15

27. Nor Shahidah Khairullah (2000). Principles of ICH GCP 3rd Ministry of Health- Academy of Medicine Scientific Meeting ; pg 57

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28. Nor Shahidah Khairullah (2000). Malaysian Guidelines on Good Clinical Practice 3rd Ministry of Health-Academy of Medicine Scientific Meeting ; pg 60

29. Roziyah Yusup, Nor Shahidah Khairullah,Yasmin Othman and Rohana Yusof (1999) Comparison of Nucleotide Acid Sequences of the 3’ Noncoding Region of Malaysian Dengue-3 viruses .11th National Biotechnology Seminar , 22-24 November: 268-269

30. HM Cheng and NS Khairullah (1998) : CMV Infection and antiphospholipid antibody production. Clinical Infectious Diseases

31. YF Ngeow, AF Weil, NS Khairullah, MY Mohd Yusof, L Lam, C Gaydos and TC Quinn (1997)Young Malaysian Children with Lower Respiratory Tract Infections Show Low Incidence Of Chlamydial Infection. J.Paediatr. Child Health ; 33:422-425

32. HM Cheng and NS Khairullah (1997) : Hepatic virus and antiphospholipid antibodies .Hepatology : 25(3) : 781-782

33. NS Khairullah, CK Wong and CK Koh (1996) : Prevalence of varicella-zoster virus antibodies in the University Hospital, Kuala Lumpur : WESPAC 1998 :184

34. NS Khairullah, PS Hooi, LL Chan and CT Chua (1996) : The diagnosis of human cytomegalovirus infections in the University Hospital, Kuala Lumpur. The Malaysian Journal of Medical Laboratory Sciences. 13(i) : 15-17

35. MY Fong, NS Khairullah and N. Ariffin (1996) : Detection of human cytomegalovirus in human leucocytes by polymerase reaction : an evaluation of two primers. The Malaysian Journal of Medical Laboratory Sciences. 13(i) : 15-17

36. KB Chua, NS Khairullah et al. (1996) : Infectious mononucleosis-like syndrome - a report of 5 cases. The Medical Journal of Malaysia

37. EH Boxall and NS Khairullah (1996) : Spectrum of persistence of anti HBc lgM antibodies in acute hepatitis B 1X Triennial International Symposium on Viral Hepatitis and Liver Disease, Rome Italy : 135

38. KB Chua, NS Khairullah and PS hooi (1996) : Seroepidemiology of human herpesvirus 6 in a population seen in the University Hospital, Kuala Lumpur, Malaysia. Southeast Journal of Tropical Medicine and Public Health; 27 : 1: 91-95

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39. NS Khairullah (1996): Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens. Malaysian Journal of Pathology; 18 (1) : 27-30

40. Chong SS, Khairullah NS, Koh CL (1995): Expression of a Carboxy-terminally truncated protein of dengue 3 virus in insect cells by a recombinant Baculovirus. Proceedings of the 7th National Biotechnology Seminar : 124-126

41. NS Khairullah and SK Lam (1995): Evaluation of WHO monoclonal antibody kits for diagnosis of acute respiratory viral infection. Southeast Journal of Tropical Medicine and Public Health : 26:2:263-267

42. NS Khairullah, KB Chua, CA Razali and PS Hooi (1995) : Comparative Evaluation of two monoclonal antibody kits for the detection and typing of respiratory viruses. Progress in Clinical Virology Joint meeting of European Group for Rapid Viral Diagnosis: 245

43. CA Razali, PS Hooi and NS Khairullah (1995): Comparison between standard tube and shell vial assay for the isolation of viruses in clinical specimens. 6th ASEAN Conference in Medical Laboratory Technology : 124

44. NS Khairullah (1995) : Respiratory Virus Surveillance in Malaysia. Pacific Basin Respiratory Virus Research Group Newsletter Vol 3 No 1 : 6

45. NS Khairullah, EH Boxall, JA Shirley (1994) : Rapid Dissappearance of anti-HBc IgM in patients with acute hepatitis B infection. Progress in Clinical Virology : Joint Meeting of European Group for Rapid Viral Diagnosis and Encephalitis group : 109

46. NS Khairullah (1994) “ Respiratory virus in Malaysia. Pacific Basin Respiratory Virus Research Group Newsletter Vol 2 No1 : 5

47. M Grandien, NS Khairullah and CR Madeley (1992) : Use of monoclonal antobodies for rapid diagnosis of respiratory viruses. Bulletin of the WHO; 70(60) : 699-70

48. MY Yusoff, NS Khairullah, PS Hooi (1992), Serological diagnosis of Mycoplasma pnuemonia respiratory tract infection in the University Hospital. Silver Jubilee Celebrations of the University Hospital.

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49. TS Soo-Hoo, NS Khairullah, KP Ng (1992) : Infections in immunocompromised patients. Silver Jubilee Celebrations of the University Hospital.

50. NS Khairullah (1991) : Baculovirus Expression of Dengue -3 virus envelope protein, Annual report from WHO Collaborating Centre For Arbovirus Reference and Research (Dengue and Dengue Haemorrhagic Fever); 10-11

51. NS Khairullah and PR Young (1990): Immunoblot and enzyme immunoassay analysis of human antibody responses to dengue infections. Proceedings of the 3rd National Biology Seminar and the First Scientific meeting of the Malaysian Society of Molecular and Cellular Biology : 3-4.

52. NS Khairullah, CM Teoh, SC Ng, GE Kua (1990) : Prevalence of cytomegalovirus antibodies in University Hospital Blood Donors. Tropical Biomedicine ;7: 125-127

53. NS Khairullah. Influenza surveillance in Malaysia (1990). Weekly Epidemiology Report, WHO Geneva : 4(2) : 248

54. NS Khairullah (1990) : Cytomegalovirus and Bone Marrow transplantation. Medical Microbiology Bulletin

55. NS Khairullah and PR Young (1989): Human antibody responses to dengue virus infections 14th Annual and General Scientific. Meeting of the Malaysian Society of Pathologists; 19

56. NS Khairullah (1989) Working Towards Prevention of Diarrhoeal Diseases in Malaysia. WHO programme for Control of Diarrhoel Diseases

57. S Devi and NS Khairullah (1988) : Diagnosis of Japanese encephalitis by IgM capture assay. 25th Silver Jubilee Celebrations of the Faculty of Medicine, University Malaya.

58. NS Khairullah, Z Manaf and YF Ngeow (1986) : Comparative Evaluation of two methods for the serological diagnosis of Chlamydia trachnomatic infection. Malaysian Journal of Pathology : 8:71-74

59. NS Khairullah, SK Lam, CH Lee (1986) : Evaluation of Herpes Simplex reagents. Exchange Newsletter for Southeast Asia and Western Pacific Region : 2(4).

Research Reports

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1) NS Khairullah. Regional Report from Southeast Asia and Western Pacific Region on the usefulness of a WHO monoclonal antibody kit for the diagnosis of respiratory viruses. WHO, Geneva, Switzerland : 25-27th March 1992.

2) NS Khairullah. Humoral responses to dengue virus proteins in patients with dengue and dengue haemorrhagic fever. Thesis submitted for part fulfillment of the degree of Master of Science in Virology; London School of Hygiene and Tropical Medicine : 1988.

CORPORATE PAST APPOINTMENTS

JOB DESCRIPTION

1. MEDICAL DIRECTOR, ELI LILLY Malaysia Sdn Bhd & Singapore Pte Ltd ( April 1998-January 1999)

Malaysian Operations

1. Clinical Trials

a. Responsible for the overall planning, execution and reporting of clinical trial in line with

affiliate objectives

b. Establishment of letter of agreements generic to local and regional trials

c. Establishment of the safety and efficacy of new drugs by excercising pharmacovigilance

2. Quality System Implementation

a. Establish policies and procedures for the implementation, pertaining to approval of medical information (clinical papers) and all forms of promotional materials in both hard or electronic copy for Sales and Marketing

b. Provide appropriate medical input into patient information leaflets, launch letters for commercialisation

3. Customer Relations

a. Set up Advisory/Focus groups comprising of Key Opinion Leaders for therapuetic areas

to foster ties and develop confidence for strategic marketing

b. Assist in conducting marketing research

c. Facilitate round table discussions twice a year during Advisory/Focus group meetings

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d. Participate in Committees/Organising Committees in Professional associations / scientific Meeting respectively to strenghten customer relationship and create presence

e. Organise and coordinate appropriate scientific sessions for Annual Symposium for CME accreditation

4. Sales and Marketing Support

a. Conduct at least two clinical training sessions a month for Sales and Marketing staff in Malaysia and Singapore

b. Review clinical papers with Marketing personnel as and when required

c. Assist and advice in activities for clinical lifeplan of products and launching of new products

5. Regulatory

a. Develop good relationship with Key Government Regulatory Personnelb. Ensure timely submission of Registration Dossiers in line with Affiliate

strategy

Regional Operations

a. Act as Overall Medical Regional Advisor for Infectious Diseases portfolio for Lilly Asia Pacific

b. Advisory, supervision and Sign off and Approval of Clinical Trials Protocol and Clinical Report Forms

c. Analysis ,Report and Control of Adverse Events For Clinical trials, spontaneous and post marketing

d. Consultant Support to Regional Infectious Disease Marketing Managere. Drive the formation of Regional Advisory Boardf. Drive Medical Response Defence to competitor marketing attackg. Advisory on Medical Content of IT program for Marketing

2. MEDICAL DIRECTOR, SPECIALTY MEDICAL LABORATORY (1997-1998)

Laboratory Operations

Consults in the development of new procedures for ultimate transfer to clinical laboratory and approve the release of new testing procedures.

Consults with the appropriate technical staff to ensure appropriate quality control parameters, policies and procedures and related documentation are developed.

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Consults with key individuals to plan test development strategies. Examines potential marketability of tests, consults the technical personnel to evaluate resource requirements.

Directs the maintenance of all required data documenting the development of each procedure transferred to the clinical laboratory and establish on-going monitoring efforts. Directs technical staff in the trouble-shooting of problematic assays in Clinical Laboratory. Works with the appropriate Technical staff to provide lasting solutions to identified problems.

Evaluates the potential for implementing of improvements in existing clinical procedures as suggested by technical staff.

Directs the verification and quality control of reagents and control materials utilised in procedures. Maintains reference standards and other materials necessary for future assay evaluation.

Develop a technologist/technician training and/or cross-training and review plan.

Assists Client Services department as required by receiving technical calls from clients and sales staff.

Hires, evaluates and counsels staff required. Evaluates Human Resource staffing needs and consults with Human Resources department to maintain sufficient staff within the laboratory.

Ensures laboratory compliance with College of American Pathologists (CAP) regulations

Lead the development of an external quality assessment scheme or an equivalent association in conjunction with SLA and Specialty staff.

Provide QC review for the Diagnostic Manufacturing Division of Specialty.

Obtain CAP accreditation and IEC/ISO G25 for the laboratory 1998.

Sales And Marketing

Coordinate the development of the Clinical Trials Business of Specialty.

Oversee the development of technical/scientific seminars in conjunction with Sales and Marketing for presentation by the Sales Team along the lines of the Specialty Speaker’s Bureau with the focus on the introduction of new technologists to Malaysia : Flow Cytometry, IHC, Image Analysis, PCR and bDNA.

Provide direct sales and marketing support in the field with Specialty Technical Sales Executives in the closure of laboratory services agreements with hospitals, clinics and laboratories in Malaysia and Singapore.

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Prepare and implement a schedule of Seminars to be given by Senior Scientific and or technical staff in Malaysia.

Participate in the presentation of proposals in the major private hospitals as needed by the Sales Team.

Assist in melding a cohesive management team in Specialty for both laboratory , sales

and marketing.

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