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Brenda W.J.H. Penninx, Ph.D page 1 CURRICULUM VITAE BRENDA WJH PENNINX, PH.D. DATE June 2010 WORK ADDRESS Department of Psychiatry VU University Medical Center, AJ Ernststraat 887 1081 HL Amsterdam, The Netherlands Tel: +31 20 7885437 Fax: +31 20 7885664 E-mail: [email protected] or [email protected] DATE OF BIRTH July 27, 1970 PLACE OF BIRTH Beuningen CITIZENSHIP Dutch EDUCATION 1988-1989 Undergraduate, BIomedical Health Sciences, Catholic University of Nijmegen, The Netherlands. Degree obtained on August 29, 1989. 1989-1992 Graduate, Master of Science in Epidemiology, Biomedical Health Sciences, Catholic University of Nijmegen, The Netherlands. Degree obtained on August 28, 1992. 1992-1996 Ph.D. in Medicine, Faculty of Medicine, Vrije Universiteit Amsterdam, The Netherlands. Degree obtained on October 4, 1996. ACADEMIC AFFILIATIONS 2007-present Professor of Psychiatric Epidemiology, Department of Psychiatry / EMGO+ Institute / Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands. 2004-present Joint Professor, Departments of Psychiatry, Leiden University Medical Center and University Medical Center Groningen, The Netherlands. 2004-2007 Associate Professor, Department of Psychiatry / EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands.

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Page 1: CURRICULUM VITAE - EMGO · Web viewCurriculum Vitae Brenda WJH Penninx, Ph.D. Date June 2010 Work Address Department of Psychiatry VU University Medical Center, AJ Ernststraat 887

Brenda W.J.H. Penninx, Ph.D page 1

CURRICULUM VITAE

BRENDA WJH PENNINX, PH.D.

DATE June 2010WORK ADDRESS Department of Psychiatry

VU University Medical Center, AJ Ernststraat 8871081 HL Amsterdam, The NetherlandsTel: +31 20 7885437Fax: +31 20 7885664E-mail: [email protected] or [email protected]

DATE OF BIRTH July 27, 1970PLACE OF BIRTH BeuningenCITIZENSHIP Dutch

EDUCATION1988-1989 Undergraduate, BIomedical Health Sciences, Catholic University of

Nijmegen, The Netherlands. Degree obtained on August 29, 1989.1989-1992 Graduate, Master of Science in Epidemiology, Biomedical Health Sciences,

Catholic University of Nijmegen, The Netherlands. Degree obtained on August 28, 1992.

1992-1996 Ph.D. in Medicine, Faculty of Medicine, Vrije Universiteit Amsterdam, The Netherlands. Degree obtained on October 4, 1996.

ACADEMIC AFFILIATIONS2007-present Professor of Psychiatric Epidemiology, Department of Psychiatry / EMGO+ Institute /

Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.

2004-present Joint Professor, Departments of Psychiatry, Leiden University Medical Center and University Medical Center Groningen, The Netherlands.

2004-2007 Associate Professor, Department of Psychiatry / EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands.

2002-2003 Associate Professor, Departments of Internal Medicine and Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem NC.

2000-2001 Assistant Professor, Departments of Internal Medicine and Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem NC.

1998-2000 Senior Researcher, EMGO Institute, VU University Amsterdam, The Netherlands.1998-1999 Visiting Scientist, Epidemiology, Demography and Biometry Program, National

Institute on Aging, Bethesda, MD.1996-1997 Visiting fellow, Epidemiology, Demography and Biometry Program, National Institute

on Aging, National Institutes of Health, Bethesda, MD.1992-1996 PhD-student, EMGO Institute, VU University, Amsterdam, The Netherlands.

OTHER PROFESSIONAL EXPERIENCE AND COMMITTEE INVOLVEMENT

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Brenda W.J.H. Penninx, Ph.D page 2

2010-present Jury member, Heineken Young Scientists Awards, KNAW2010-present Member, Scientific Committee for the LifeLines study.2007-present Member, VIDI review committee, NWO2008-2012 Member, Selection committee for the Dr. Hendrik Muller Award voor Gedrags- en

Maatschappijwetenschappen. KNAW 2007-present Member of Health Council Committee, Committees ‘Predictive Medicine’ and

‘Undernutrition in the Elderly’2006-present Member, Rubicon review committee, NWO2006-present Member, KNAW commissie Internationaal beleid2005-2010 Member, Young Academy, KNAW2004-present Program leader, Mental health program, EMGO Institute, VU University Medical

Center, Amsterdam2004-present Scientific Director, Netherlands Study of Depression and Anxiety (NESDA)2000-2003 Director, Geriatric Research Center, Wake Forest University School of Medicine,

Winston Salem, NC.2001 Consultant for the working group on ‘Prevention of disability in frail older persons’.

Meeting in Florence, Italy.2001 Consultant in Healthy Brain Aging workshop, a NIH appointed advisory panel, co-

sponsored by National Institute on Aging, National Institute of Mental Health and National Institute of Neurological Disorders and Stroke.

HONORS AND AWARDS2006 Fellow, Gerontological Society of America2005 Member, The Young Academy of the Royal Dutch Academy of Sciences and Arts.2000 Fellowship, Brookdale Foundation Leadership on Aging award, Brookdale

Foundation, New York.1988 Epidemioloog B (registered senior epidemiologist) by the Netherlands Society of

Epidemiology1997 EMGO-Award from the VU University, for best scientific article in 1997. 1996 Stipend, Niels Stensen Stichting Amsterdam for a visiting fellowship at the National

Institute on Aging in Bethesda, MD, USA ($0.1 million) in 1996.1994 Scholarship award obtained from Royal Dutch Academy of Arts and Sciences

(KNAW) to attend the Epidemiology Summer School, New England Epidemiology Institute, Boston MA, USA.

1994 'Dittmer fund' award from VU University for attending the Epidemiology Summer School, New England Epidemiology Institute, Boston MA, USA.

SOCIETY MEMBERSHIPNetherlands Society of Epidemiology (1992 - present)Dutch Federation of Medical Scientific Societies (1992 - present)Gerontological Society of America (1996 - present)American Psychosomatic Medicine Association (2006-present)Young Academy, Royal Dutch Academy of Sciences and Arts (2005-2011)

TEACHING EXPERIENCE‘Mental Health Research’, research master course in biomedical sciences, 200 credit hours, VU

University, 2009‘Psychiatric Epidemiology’, Postdoctoral Education Epidemiology (POE), VU University Medical

Center, 2007, 2008, 2009

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Brenda W.J.H. Penninx, Ph.D page 3

‘Psychosomatic Medicine’, Course in honours program for excellent interdisciplinary students, 200 credit hours, VU University Amsterdam, February-March 2008.

‘Social environment and health’, Postdoctoral education, Netherlands Institute of Health and Environmental Sciences (NIHES), Rotterdam, The Netherlands, 2005-2008.

Geriatrics Fellows training on ‘Physical health consequences of late-life depression’, Wake Forest University School of Medicine, in 2002, 2003, 2005.

'Population Health and Epidemiology', Wake Forest University School of Medicine 20 credit hours for medical students, 2001 - 2003.

Journal club for fellows, Section Geriatrics, Department of Internal Medicine, Wake Forest University School of Medicine, 2000 - 2003, one hour bi-weekly.

'Basic principals in epidemiologic research'. Post Doctoral Training Program in Epidemiology. VU University, 40 credit hours, 8 students, 1999.

'Logistic regression and survival analyses'. Post Doctoral Training Program in Epidemiology. VU University, 40 credit hours, 10 students, 1996 and 1998.

'Basics of Biostatistics'. Post Doctoral Training Program in Epidemiology. VU University, 10 credit hours, 30 students, 1996.

SUPERVISION OF PH.D STUDENTSGRADUATED1. Graziano Onder, Wake Forest University, Winston Salem, Graduated in April 2002. Thesis:

ACE-inhibitors and physical decline in old age.2. Arlette Hesselink, Vrije University. Graduated on October 17, 2003. Thesis: Educating

asthma and COPD patients in general practice.3. Matteo Cesari, Wake Forest University School of Medicine, Winston Salem, Graduated in

November 2004. Thesis: Inflammation and cardiovascular disease in old age.4. Bianca Schalk, Vrije University. Graduated on February 11, 2005. Thesis: Albumin and

physical health decline in old age.5. Coen van Gool, University of Maastricht. Graduated on June 10, 2005. Thesis: The course

of chronic disease, depression, and health behavior in longitudinal perspective. Findings concerning the epidemiology of aging.

6. Annemarie Koster, University of Maastricht. Graduated on December 22, 2005. Thesis: Socioeconomic health differences in old age: Unraveling the roles of biomedical, behavioral and psychosocial factors.

7. Inger Plaisier, VU University. Graduated on November 26, 2009. Thesis: Mental health and work: studies on the role of gender, social roles and work characteristics.

8. Nicole Vogelzangs, VU University. Graduated on April 23, 2010. Thesis: Depression and the metabolic syndrome.

9. Lotte Gerritsen, Utrecht University Medical Center, Graduated on May 18, 2010. Topic: Stress, the brain and cognition.

10. Carmilla Licht, VU University Medical Center, Amsterdam, Graduation on October 15, 2010. Topic: Depressive and anxiety disorders and the autonomic nervous system.

11. Sophie Vreeburg, VU University Medical Center, Amsterdam, Graduation on October 22, 2010. Topic: Depressive and anxiety disorders and the hypothalamus-pituitary-adrenal (HPA) axis.

CURRENTLY ACTIVE PHD-TRAJECTORIES (ROLE: PROMOTOR)1. Arianne van Reedt-Dortland, Leiden University, 2006-2011. Topic: Metabolic syndrome and

psychopathology.2. Didi Rhebergen, VU University, 2005-2011. Topic: Dysthymia.

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Brenda W.J.H. Penninx, Ph.D page 4

3. Jeroen van Zanten, VU University, 2006-2011. Topic: Gene-expression profiles in depressed patients.

4. Pierre Bet, VU University, 2005-2011. Topic: Pharmcogenetic determinants of psychopathology.

5. Floriana Lupino, Leiden University, 2006-2011. Topic: Psychiatric in-patients, metabolic syndrome and psychopathology.

6. Klaas Wardenaar, Leiden University, 2006-2011. Topic: Dimensional characterization of psychopathology.

7. Julie Karsten, University of Groningen, 2007-2011. Topic: Trait, state or residual state: a focus on participants with subthreshold affective problems.

8. Adrie Seldenrijk, VU University, 2007-2010. Topic: Subclinical cardiovascular risk and depression.

9. Leonie Manthey, Leiden University, 2008-2012. Topic: Use of benzodiazepine: prevalence and biological and genetical determinants.

10. Josine van Mill, VU University, 2007-2012. Topic: Sleep disorders among persons with anxiety and depression.

11. Lynn Boschloo, VU University, 2008-2012. Topic: Alcohol use disorders among persons with anxiety and depression.

12. Marc Molendijk, Leiden University, 2008-2012. Topic: BDNF and cognition.13. Anne-Laura van Harmelen, Leiden University, 2008-2012, Topic: Trauma and cognition.14. Hester Duivis, Tilburg University, 2008-2012, Topic: Inflammation and depression.15. Jacqueline Hovens, Leiden University, 2009-2012. Topic: Life-events and personality in

depression.16. Merijn Eikelenboom, VU University, 2009-2012. Topic: Suicidal behavior 17. Marloes Gerrits, VU University, 2009-2013. Topic: Depression and somatic health in primary

care.18. Abdel Abdellaoui, VU University, 2010-2013. Topic: Genetics and genomics of depression.19. Nicole Korten, VU University, 2010-2013. Topic: Stress, vulnerability and cognition.

MEMBER OF THE DISSERTATION/OPPOSITION COMMITTEE 2004 Isabella Bischop, VU University; Max Stek, VU University2005 Marleen Hermens, VU University; David Vinkers, Leiden University; Nina Kupper, Vrije

University2006 Christel Middeldorp, Vrije University; Anneke van Schaik, VU University; Marjolein

Kamphuis, University Utrecht2007 Koen van der Kooy, VU University; Wendelien Merens, Leiden University2008 Els Licht, VU University; Miriam Knol, University Utrecht; Sannie Hamerlynck, VU University;

Marijke Bremmer, VU University; Kristen Kaptein, University of Groningen.2009 Marit Tanke, University of Groningen; Jasper Nuijen, VU University; Ceren Acarturk, VU

University; Jaap Peen, VU University; Maaike Verhagen, Radboud University Nijmegen; Geeske Peeters, VU University; Iris Lepolder, VU University.

2010 Neeltje Batelaan, VU University; Peter Meulenbeek, VU University; Gerthe Veen, Leiden University; Arnoud Knoops, University Utrecht; Esther Bouma, University of Groningen; Lannie Ligthart, VU University; Lisanne Warmerdam, VU University.

EDITORIAL EXPERIENCEMember of the Editorial Boards of the:

- Journal of Gerontology: Medical Sciences (2005 – current)- European Journal of Aging (2005 – current)

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- International Journal of Behavioral Medicine (2006 - current)In addition, peer reviewer for many (>25) different medical journals.

GRANTS

BBMRI-NL: Biobanking and Biomolecular Resources Research Infrastructure. Project title: Completion of GWAS for the NESDA biobank. Period: 2010-11.Total amount: €50,000. Role: PI.

Royal Netherlands Academy of Science and Arts (KNAW). Funds to hold the ‘Genomics of gene expression conference’, January 7-8 2010. Penninx/Boomsma. Total amount: €25,000. Role: Applicant.

Neuroscience campus Amsterdam, VU University/VU University Medical Center, Postdoc funds for annotation of genes for depression. Period: 2/2010-1/2012. Total amount: €60,000. Role: PI

Neuroscience campus Amsterdam, VU University/Vu University Medical Center, Postdoc funds for gene expression of alcohol and smoking addiction. Period: 2/2010-1/2012. Total amount: €60,000. Role PI.

Neuroscience campus Amsterdam, VU University/VU University Medical Center, Biomarker funds for inflammation. Period 10/2009-9/2011. Total amount: €40,000. Role: PI

Neuroscience campus Amsterdam, VU University/VU University Medical Center, Biomarker funds for cotinine. Period 10/2009-9/2011. Total amount: €12,000. Role: PI.

National Institute of Mental Health, National Institutes of Health. MH089951-01. Project title: Integration of genomics and transcriptomics in normal twins and major depression. PI: Sullivan. Period 10/2009-9/2011. Total amount $6,5 million. Role: Co-PI

Center for Medical Systems Biology (CMSB2): Multifactorial Diseases: Common Determinants, Unifying Technologies (PI: van Ommen) NWO Genomics: €0.52 million; 2008 – 2012. Role: Co-PI on depression section of CMSB2.

National Institute of Mental Health (NIMH, RFA-MH-08-120). Project title: Psychiatric Genetic Consortium. Period: 09/2008-09/2010. $77,760. Role: PI

National Institute of Mental Health (NIMH), subcontract to 1R01MH081802 (PI Sullivan, University of North Carolina). Project title: Major Depression: Stage 1 genomewide association in Population-based Samples. Period: 09/2007-09/2008. $34,048. Role: Co-PI.

Stichting steun VCVGZ. De Nederlandse Studie naar Depressie bij Ouderen (NESDO). PI: Comijs. Period: 2007-9. €80,000. Co-I.

Addiction grant, ZonMW, The Netherlands. Project title: Development of alcohol use disorders: the role of clinical, psychological, environmental, genetic and neurophysiological factors. Period: 4/2008-3/2013. € 700,000. Role: PI

European Network of Genetic And Genomic Epidemiology (ENGAGE), funded through the European Community’s Seventh Framework Program (FP7-2007/2013), HEALTH-F4-2007-201413. Period:11/2007-10/2010. $150,000. Role Co-I.

Foundation of the National Institutes of Health, subcontract to Sulliv06GAIN0 (PI Sullivan Univerisity of North Carolina), Project title: Gain study Major Depression: Stage 1 genomewide association in Population-based Samples. Period: 1/2007-12/2007. $28,810. Role: PI

GAIN grant, foundation for National Institute of Health (fNIH), USA. Project title: Major Depression: Stage 1 Genomewide Association in Population-Based Samples.Period:

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Brenda W.J.H. Penninx, Ph.D page 6

10/2007-10/2009. 4000 genome wide association scans worth ~2 million USD. Role: co-PI (PI: Patrick Sullivan, UNC, Chapel Hill, NC).

Stichting steun VCVGC. Pilot studie voor implementatie van Cognitive behavioural analysis system of psychotherapy (CBASP) voor chronische depressies’. PI: Van Oppen. Period: 2006-8. € 45,000. Role: Co-I.

ZonMW, program mental health (care project). Project title: The effectiveness of CBASP for chronic depression. PI: van Oppen. Period: 7/2006-6/2009. €200,000. Role: Co-I.

Netherlands Heart Foundation. Project title: Which pathways determine cardiovascular problems for patients with affective disorders? Extension of the Netherlands Study of Depression and Anxiety. PI: van Hout. Period:10/2006-9/2009. €170,000. Role: Co-I.

OOG grant, Geestkracht program, ZonMW, The Netherlands. Project title: HPA-axis dysfunction in patients with affective disorders: To whom does it concern? Candidate: Berend Verhoeff. Period: 1/2006 - 30/2011. Total amount: 115.000 Euro. Role: PI

VIDI grant, ZonMW, the Netherlands. Project title: The pathophysiology of depression and anxiety disorders: an epidemiological examination of the roles of the HPA-axis and the autonomic nervous system. Period: 1/2006 - 31/2010. Total amount: 600.000 Euro. Role: PI

ZonMW, program mental health (Geestkracht program). Project title: Netherlands Study of Depression and Anxiety (NESDA). Period: 12/2003 - 11/2012. €4,300,000. Role: PI

ZonMW, programma doelmatigheid. Development of organizational interventions to improve compliance with guidelines on depression and anxiety in primary care. PI: Verhaak. Period 5/06– 4/09. €250,000. Role: Co-I.

ZonMW, program addiction. Project title: Comorbidity of Addiction and Depression/Anxiety. PI: Beekman. Period: 12/03-12/07. €150,000. Role: Co-I.

National Heart, Lung and Blood Institute - Institutes of Health. 1R01 HL972972. Project title: The epidemiology of stress and the metabolic syndrome. Period: 09/2003 - 08/2007. $1,027,445. Role: PI.

National Institutes of Health: Claude D. Pepper Older Americans Independence Center Grant, NIH-NIA P30 AG AG21332. PI: Pahor. Period: 10/02 - 09/07. $5,665,725. Role: Co-I and PI on pilot project core.

Ortho Biotech Products, Project title: Fellowship grant: Training geriatric fellows in anemia research. Period: 7/2002 - 6/2004, $175,000. Role: PI.

National Institutes of Health. Project title: ACE inhibitors and novel cardiovascular risk factors, PI: Pahor. Period: 4/02 - 3/05, $1,400,000. Role: Co-I

National Institutes of Health, R21 AG193532. Project title: ‘Exercise to prevent disability and cardiovascular events’, PI: Pahor. Period: 4/01 - 3/02, $217,125. Role: Co-I.

Claude D. Pepper Center on Aging, Wake Forest University, Project title: Efficacy and effectiveness of an exercise program and antidepressant medication on emotional and physical health in older persons with minor depression. Period: 7/01 - 6/02, $25,000. Role: PI

Ortho Biotech Products, Project title: Physical health consequences of anemia in old age. Period: 1/2001 - 12/2002, $101,000. Role: PI

Netherlands Health Care Research Organization. Project title: Feasibility and effectiveness of a transmural psychotherapy intervention for general practice patients with late-life depression. Period: 4/2001 - 3/2004. €150,000. Role: PI

Dutch Sickfund Organization, Project title: (Cost)effectiveness of antidepressant drugs in general practice patients with minor depression. Period: 7/2001 - 6/2004, €700,000. Role: PI

Netherlands Scientific Organization (NWO-CZ). Project title: Genetic and biological risk factors for cardiovascular morbidity and mortality in depressed elderly. PI: Hoogendijk. Period 2001-2005. €150.000. Role: Co-I.

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Brenda W.J.H. Penninx, Ph.D page 7

Brookdale Foundation, Brookdale Foundation Leadership on Aging award, Project title: The role of inflammation and health behavior in the detrimental physical health consequences of late-life depression, Period: 07/2000 - 06/02, $115,000. Role: PI

Women's Health Center of Excellence, Wake Forest University, Project title: The effect of an exercise program and antidepressant medication on emotional and physical health in older women with minor depression'. Period: 10/00 - 9/01, $12,500. Role: PI

Netherlands Scientific Organization (NWO). Project title: Prognosis of major and minor depression in older primary care patients. PI: van Marwijk. Period: 2000-2004. €150.000. Role: Co-I

“Breedtestrategie of the VU University”. An interfacultary research program funded by VU University and Ministry of Welfare, Health and Sports. Project title: Frailty and vitality in aging: an interdisciplinary approach. Period: 1999-2004. € 1.7 million. Role: PI on subproject on depression.

Vrije University Amsterdam. Project title: Biological frailty markers as predictors of physical health decline in older persons. Period: 10/1999 - 9/2003. €150,000 euro. Role: PI (after leaving VU, Co-I)

Netherlands Scientific Organization (NWO-CZ). Project title: ‘The influence of social support and personal coping resources on phyiscal and mental functioning of elderly people with different chronic diseases. PI: Kriegsman. Period 1998-2002. €150.000. Role: Co-I.

Vrije University Amsterdam, The Netherlands. Project title: Effectiveness of patient-focused, multidisciplinary care for patients with asthma and COPD. Period: 1/1998 - 12/2001. €150,000. Role: PI

Netherlands Scientific Organization (NWO). Project title: Effects of psychological factors on the onset and course of cardiovascular disease in the elderly. Period: 4/1998 - 3/2000. €150,000. Role: PI

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PUBLICATIONS IN PEER REVIEWED JOURNALS

1. Teslovich TM, Musunuru K, Smith AV, Edmondson A, Stylianou IM, Koseki M, Rapatti S, Chasman DI, Willer CJ, Pirruccello J, Johansen CT, Fouchier SW, Isaacs A, Peloso G, Barbalic M, Ricketts SL, Bis JC, Aulchenko Y, Thorleifsson G, Feitosa M, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Zhao JH, Yuan X, Luan J, CARDIoGRAM Consortium, ENGAGE Consortium, Candidate Gene Association Resource (CARe) Lipids Working Group, Waterworth DM, Wareham NJ, Zhang W, Zee RYL, Wright AF, Witteman JCM, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Tanaka T, Surakka I, Stringham HM, Spector TD, Smit JH, Silander K, Sijbrands EJG, Scuteri A, Scott J, Schunkert H, Schlessinger D, Sanna

S, Samani N, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL, Pattaro C, Parker

AN, Pare G, Oostra BA, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Magnusson P, Lucas G, Luben R, Loos RJF, Lindqvist I, Lettre G, Launer LJ, Lakatta EG, Kyvik KO, Kronenberg F, Inke Koenig

I, Khaw KT, Kaprio J, Kaplan KM, Jonasson I, Johansson A, Jarvelin MR, Janssens CJW, Ingelsson E, Hovingh GK, Hottenga JJ, Holm H, Hofman A, Hicks AA, Heid IM, Hayward C, Hastie ND, Harris TB, Haritunians T, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger

C, Freimer NB, Falchi M, Erdmann J, Elliott P, Ejebe K, Döring A, Demissie S, Deloukas P, de Geus EJC, de Faire U, Crawford G, Collins FS, Chen YI, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Assimes TL, Altshuler

D, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA, Borecki IB, Gabriel SB, Wilson JG, Stefansson K, Thorsteindottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall A, Hegele RA, Kastelein JJP, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn CN, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S for the Global Lipids Genetics Consortium. Biological, Clinical, and Population Relevance of 95 Loci Mapped for Serum Lipid Concentrations. Nature 2010; in press.

2. Lewis T, Sutton-Tyrrell K, Penninx BW, Vogelzangs N, Harris TB, Vaidean GD, Ayonayon H, Newman AB. Race, psychosocial factors and aortic pulse wave velocity. The Health, Aging and Body Composition Study. J Gerontol: Med Sci 2010; in press.

3. Vreeburg S, Hartman C, Ormel J, Zitman F, Hoogendijk W, Penninx BW. Familial risk and cortisol function. Br J Psychiatry 2010; in press.

4. Boschloo L, Vogelzangs N, Smit JH, van den Brink W, Veltman DJ, Beekman ATF, Penninx BW. The performance of the Alcohol Use Disorder Identification Test (AUDIT) in detecting alcohol abuse and dependence in a population of depressed or anxious persons. J Affect Dis 2010; in press.

5. Demirkan A, Penninx BW, Hek K, Wray N, Amin N, Hek K, Aulchenko YS, van Dyck R, de Geus EJ, Hofman A, Hottenga JJ, Nolen WA, Oostra B, Sullivan PF, Willemsen G, Zitman FG, Tiemeier H, Janssens CJ, Boomsma DI, van Duijn CM, Middeldorp CM. Genetic risk score profiling for depression and anxiety using genome-wide association data in three Dutch samples. Mol Psychiatry 2010; in press.

6. Prins M, Bosmans J, Verhaak P, van der Meer K, van Tulder M, van Marwijk H, Penninx BW, Bensing J. Costs of anxiety and depression care. Guideline-concordant care and needs-

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Brenda W.J.H. Penninx, Ph.D page 9

concordant care: what is more expensive? Journal of Evaluation in Clinical Practice 2010; in press.

7. Ligthart L, Nyholt DR, Penninx BW, Boomsma DI. The shared genetics of migraine and anxious depression. Headache 2010; in press.

8. Spijker S, Van Zanten JS, De Jong S, Penninx BWJH, van Dyck R, Smit JH, Ylstra, B, Smit AB, Hoogendijk, WJG. Molecular markers of Major Depressive Disorder based on stimulated gene expression in drug-naive blood samples. Biol Psychiatry 2010; in press.

9. van der Feltz-Cornelis C, de Graaf R, ten Have M, Penninx BW, Smit JH, Beekman AT. Patterns of mental health care utilization in subjects with common mental disorder with and without comorbid somatic disorder. Findings from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Psychiatr Serv 2010; in press.

10. van den Berg B, Penninx BW, Jabben N, Zitman FG, Nolen WN. Manic symptoms in patients with depressive and/or anxiety disorders. J Affect Dis 2010; in press.

11. Vogelzangs N, Seldenrijk A, Beekman AT, De Jonge P, van Hout H, Penninx BW. The prevalence of CVD in a large psychiatric sample: Results from NESDA. J Affect Dis; in press.

12. Klabbers G, Bosma H, van der Does A, Vogelzangs N, Kempen GIJM, van Eijk JT, Penninx BW. The educational patterning of health-related adversities in major depressed patients. A cross-sectional study. J Affect Dis; in press.

13. Bosker FJ, Hartman CA, Nolte I, Prins BP, Willemsen G, Posthuma D, de Rijk R, van Veen T, de Geus EJ, Hoogendijk WJ, Sullivan PF, Penninx BW, Boomsma DI, Snieder H, Nolen WA. Poor replication of candidate genes for major depressive disorder using a genome-wide association data. Mol Psychiatry 2010; in press.

14. Van Harmelen A, de Jong PJ, Glashouwer KA, van Dyck R, Spinhoven Ph, Penninx BW, Elzinga BM. Childhood abuse and negative automatic self-associations: The cognitive scars of childhood emotional abuse. Behav Res Ther 2010; press.

15. van Reedt-Dortland AK, Giltay EJ, van Veen T, Zitman FG, Penninx BW. The metabolic syndrome in subjects with anxiety and depression disorders. Acta Psychiatr Scand 2010; in press.

16. Spinhoven P, Elzinga B, Hovens JGFM, Roelofs K, Zitman FG, van Oppen P, Penninx BW. The specificity of childhood adversities and negative life events across the lifespan to anxiety and depressive disorders. J Affect Dis 2010; in press.

17. Cuijpers P. Smit F, Penninx BW, de Graaf R, ten Have M, Beekman AT. The economic costs of neuroticism: A population-based study. Arch Gen Psychiatry 2010; in press.

18. Wiersma J, van Oppen P, van Schaik A, van der Does W, Beekman AT, Penninx BW. Personality and cognitive vulnerability and chronicity of depression. J Clin Psychiatry 2010; in press.

19. Plaisier I. Beekman ATF, de Graaf R, Smit JH, van Dyck R, Penninx BW. Work functioning in persons with depressive and anxiety disorders: The role of specific psychopathological characteristics. J Affect Dis 2010; in press.

20. Ligthart L, Penninx BW, Nyholt DR, Distel MA, de Geus EJC, Willemsen G, Smit JH, Boomsma DI. A comparison of migraine symptomatology in depressed and non-depressed individuals using latent class analysis. Cephalalgia 2010; in press.

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21. Manthey L, van Veen T, Knuisting-Neven A, Giltay E, Penninx BW, Zitman F. Benzodiazepine use and HPA-axis function. J Clin Psychopharmacol 2010; in press.

22. Seldenrijk A, Vogelzangs N, van Hout H, van Marwijk H, Diamant M, Penninx BW. Depressive and anxiety disorders and subclinical atherosclerosis. J Psychsom Res 2010; in press.

23. Wardenaar KJ, van Veen T, Giltay EJ, van Veen T, Penninx BW, Zitman FG. The dimensional structure of the Inventory of Depressive Symptomatology Self Report (IDS-SR) in patients with depressive disorders and healthy controls. J Affect Dis 2010; in press.

24. Rhebergen D, Beekman AT, Nolen WN, Spijker J, de Graaf R, Hoogendijk WJ, Penninx BW. Disabiilty and depression type: findings from NEMESIS. J Affect Dis 2010; in press.

25. Prins MA, Verhaak PF, van der Meer K, Spreeuwenberg P, Smolders M, Laurant M, van Marwijk H, Penninx BW, Bensing JM. Patient factors obstructing and facilitating guideline-compliant care for primary care patients with anxiety or depression. J Gen Int Med 2010; in press.

26. Gerritsen L, Geerlings MI, Beekman ATF, Deeg DJH, Penninx BW, Comijs HC. Childhood adversity, recent life events and salivary cortisol in older persons. Psychol Med 2010; in press.

27. Hovens JGFM, Wiersma JE, Giltay EJ, van Oppen P, Penninx BWJH, Zitman FG. Childhood life events and childhood trauma in adult patients with depressive, anxiety and comorbid disorders: The NESDA study. Acta Psychiatr Scand 2010; in press.

28. Gerritsen L, Comijs HC, Penninx BW, Deeg DJ, Geerlings MI. Salivary cortisol, ApoE-E4 allele and cognitive decline in a prospective study of older persons. Neurobiol Aging 2010; in press.

29. Liu Y, Blackwood DH, Caesar S, de Geus EJC, Farmer A, Ferreira MAR, Ferrier IN, Fraser C, Gordon-Smith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, Hoogendijk WJ, Hottenga JJ, Jones L, Jones IR, Kirov G, Lin DY, McGuffin P, Moskvina V, Nolen WA, Perlis RH, Posthuma D, Scolnick EM, Smit AB, Smit JH, Smoller JW, St. Clair D, van Dyck R, Verhage M, Wellcome Trust Case-Control Consortium, Willemsen G, Young AH, Zandbelt T, Boomsma DI, Craddock N, O'Donovan MC, Owen MJ, Penninx BWJH, Purcell S, Sklar P, Sullivan P. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. Mol Psychiatry 2010; in press.

30. Lamers F, de Jonge P, Nolen W, Zitman F, Smit JH, Beekman AT, Penninx BW. Subtypes of depression: results from NESDA. J Clin Psychiatry 2010; in press.

31. Prins MA, Verhaak PF, van der Meer K, Penninx BW, Bensing JM. Primary care patients with anxiety and depression: Need for care from the patient perspective. J Affect Dis 2010; in press.

32. Wardenaar KJ, van Veen T, Giltay EJ, de Beurs E, Penninx BWJH, Zitman FG. Development and validation of a short version of the mood and anxiety symptoms quesionnaire: the MASQ-30. Psychiatry Res 2010; in press.

33. de Wit LM, van Straaten A, Luppino F, Penninx BW, Zitman F, Cuijpers P. Depression and obesity: a meta-analysis. Psychiatry Res 2010; in press.

34. van Reedt-Dortland A, Giltay E, van Veen T, Zitman F, Penninx BW. Serum lipids and lipoproteins in subjects with current or remitted major depressive disorder and controls: the Netherlands Study of Depression and Anxiety. J Clin Psychiatry 2010; in press.

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35. Karsten J, Hartman CA, Ormel J, Nolen WA, Penninx BW. Subthreshold depression based on functional impairment better defined by symptom severity than by number of DSM-IV symptoms. J Affect Disord 2010;123:230-7.

36. Vogelzangs N, Beekman AT, Brenes G, Yaffe K, Newman AB, Harris TB, Kritchevsky SB, Penninx BW. Visceral abdominal obesity predicts occurrence of depression. J Clin Psychiatry 2010;71:391-9.

37. Glashouwer K, de Jong P, Penninx BW, Kerkhof AJ, van Dyck R, Ormel J. Do automatic self-associations relate to suicidal ideation? J Psychopathology and Behavioral Treatment 2010: in press.

38. Vreeburg SA, Zitman FG, van Pelt J, deRijk RH, Verhagen JC, van Dyck R, Hoogendijk WJ, Smit JH, Penninx BW. Salivary cortisol levels in persons with and without different anxiety disorders. Psychosom Med 2010;72:340-7.

39. Licht CM, Vreebrug SA, van Reedt-Dortland AK, Giltay EJ, Hoogendijk WJ, DeRijk RH, Vogelzangs N, Zitman FG, de Geus EJ, Penninx BW. Increased sympathetic and decreased parasympathetic activity rather than changes in hypothalamic-pituitary-adrenal-axis activity are associated with metabolic abnormalities. J Clin Endocrinol Metab. 2010;95:2458-66.

40. Penninx BW, van Dyck R. Depressie en somatische comorbiditeit [Depression and somatic comorbidity] Ned Tijdschr Geneeskd. 2010;154:A1784.

41. Tobacco and Genetics Consortium (116 co-authors including Penninx BW). Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet 2010;42:441-7.

42. Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR; ENGAGE Consortium, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010;42:448-53.

43. Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J, Luttropp K, Maréchal C, Melander O, Munroe PB, Nordfors L, Parsa A, Peltonen L, Penninx BW, Perucha E, Pouta A, Prokopenko I, Roderick PJ, Ruokonen A, Samani NJ, Sanna S, Schalling M, Schlessinger

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D, Schlieper G, Seelen MA, Shuldiner AR, Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg MJ, Swaminathan R, Tanaka T, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI, Jarvelin MR, Mooser V, Abecasis GR, Lightstone L, Scott J, Navis G, Elliott P, Kooner JS. Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 2010;42:373-5.

44. Lamers F, Jonkers CC, Bosma H, Kempen GI, Meijer JA, Penninx BW, Knottnerus A, van Eijk JTh. A minimal psychological intervention in chronically ill elderly patients with depression: a randomized trial. Psychother Psychosom 2010;79:217-226.

45. Van Mill JG, Hoogendijk WJ, Vogelzangs N, van Dyck R, Penninx BW. Insomnia and sleep duration in a large cohort of patients with major depressive disorder and anxiety disorders. J Clin Psychiatry 2010;71:239-246.

46. Koster A, Van Gool CH, Kempen GI, Penninx BW, Lee JS, Rubin SM, Tylavsky F, Yaffe K, Newman AB, Harris TB, Pahor M, Ayonayon HN, van Eijk JThM, Kritchevsky SB. Late-life depressed mood and weight change contribute to the risk of each other. Am J Geriatr Psychiatry 2010;18:236-44.

47. Antypa N, van der Does AJ, Penninx BW. Cognitive reactivity: Investigation of a potentially treatable marker of suicide risk in depression. J Affect Dis 2010;122:46-52.

48. Donker T, Comijs H, Cuijpers P, Terluin B, Nolen W, Zitman F, Penninx B. The validity of the Dutch K10 and extended K10 screening scale for depressive and anxiety disorders. Psychiatry Res 2010;176:45-50.

49. Smolders M, Laurant M, Verhaak P, Prins M, van Marwijk H, Penninx B, Wensing M, Grol R. Which Physician and Practice Characteristics are Associated With Adherence to Evidence-Based Guidelines for Depressive and Anxiety Disorders? Med Care 2010;48:240-248.

50. van Beljouw I, Verhaak P, Prins M, Cuijpers P, Penninx B, Bensing J. Reasons and determinants for not receiving treatment for common mental disorders. Psychiatr Serv 2010;61:250-7.

51. Luppino FS, de Wit LM, Bouvy PF, Stijnen T, Cuijpers P, Penninx BW, Zitman FG. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry 2010;67:220-9.

52. Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA,

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Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC; DIAGRAM Consortium; GIANT Consortium; Global BPgen Consortium, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF; Anders Hamsten on behalf of Procardis Consortium; MAGIC investigators, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42:105-16

53. Lind PA, Macgregor S, Vink JM, Pergadia ML, Hansell NK, de Moor M, Smit AB, Hottenga JJ, Richter MM, Heath AC, Martin NG, Willemsen G, de Geus EJ, Vogelzangs N, Penninx BW, Whitfield JB, Montgomery GW, Boomsma DI, Madden PA. A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Twin Res Hum Genet 2010;13:10-29.

54. Comijs HC, Gerritsen L, Penninx BW, Bremmer MA, Deeg DJ, Geerlings MI. The association between serum cortisol and cognitive decline in older persons. Am J Geriatric Psychiatry 2010;18:42-50.

55. Batelaan NM, de Graaf R, Penninx BW, van Balkom AJ, Vollebergh WA, Beekman AT. The 2-year prognosis of panic episodes in the general population. Psychol Med 2010;40:147-57.

56. Gerritsen L, Geerlings MI, Bremmer MA, Beekman AT, Deeg DJ, Penninx BW, Comijs H. Personality characteristics and hypothalamic-pituitary-adrenal axis regulation in older persons. Am J Geriatr Psychiatry 2009;17:1077-84

57. van der Veen WJ, van der Meer K, Penninx BW. Screening for depression and anxiety. Correlates of non-response and cohort attrition in the Netherlands Study of Depression and Anxiety (NESDA). Int J Meth Psychiatr Res 2009;18:229-239.

58. Ferreira MAR, Hottenga JJ, Warrington NM, Medland SE, Willemsen G, Lawrence RW,

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Gordon S, de Geus EJ, Henders AK, Smit JH, Campbell MJ, Wallace L, Evans DM, Wright MJ, Nyholt DR, James AL, Beilby JP, Penninx BW, Palmer LJ, Frazer IH, Montgomery GW, Martin NG, Boomsma DI. Sequence variants in three loci influence monocyte count and erythrocyte volume. Am J Hum Genetics 2009;85:745-9.

59. Benyamin B, Ferreira MA, Willemsen G, Gordon S, Middelberg RP, McEvoy BP, Hottenga JJ, Henders AK, Campbell MJ, Wallace L, Frazer IH, Heath AC, de Geus EJ, Nyholt DR, Visscher PM, Penninx BW, Boomsma DI, Martin NG, Montgomery GW, Whitfield JB. A common TPMRSS6 polymorphism (A736V) affects iron status, haemoglobin levels and erythrocyte volume in the general population. Nat Genet 2009;41:1173-5.

60. Estrada K, Krawczak M, Schreiber S, van Duijn K, Stolk L, van Meurs J, Liu F, Penninx BW, Smit JH, Vogelzangs N, Hottenga JJ, Willemsen G, de Geus E, Lorentzon M, von Eller-Eberstein H, Lips P, van Schoor N, Pop V, de Keijzer J, Hofman A, Aulchenko Y, Oostra BA, Ohlsson C, Boomsma DI, Uitterlinden A, van Duijn C, Rivadeneira F, Kayser M. A genome-wide association study of Northwestern Europeans involves the CNP signaling pathway in the etiology of human height variation. Hum Mol Genet 2009;18:3516-24.

61. Spinhoven P, de Rooij M, Heiser W, Smit JH, Penninx BW. The role of personality in comorbidity among anxiety and depressive disorders in primary care and specialty care: A cross-sectional analysis. Gen Hosp Psychiatry 2009;31:470-7.

62. Smolders M, Laurant M, Verhaak P, Prins M, van Marwijk H, Penninx B, Wensing M, Grol R. Adherence to evidence-based guidelines for depression and anxiety disorders is associated with recording of the diagnosis. Gen Hosp Psychiatry 2009;31:460-9.

63. Wiersma JE, Hovens JG, van Oppen P, Giltay EJ, van Schaik DJ, Beekman AT, Penninx BW. The importance of childhood trauma and childhood life events for chornicity of depression in adults. J Clin Psychiatry 2009;70:983-9.

64. Vink DM, Aartsen M, Comijs HC, Heymans MW, Penninx BW, Stek ML, Deeg DJ, Beekman AT. Onset of anxiety and depression in the aging population: comparison of risk factors in a 9-year prospective study. Am J Geriatr Psychiatry 2009;17:642-52.

65. Vogelzangs N, Beekman AT, Dik MG, Bremmer MA, Comijs H, Hoogendijk WJ, Deeg DJ, Penninx BW. Late-life depression, cortisol, and the metabolic syndrome. Am J Geriatr Psychiatry 2009;17:716-21.

66. Vreeburg SA, Kruijtzer BP, van Pelt HJ, van Dyck R, de Rijk RH, Hoogendijk WJG, Smit JH, Zitman FG, Penninx BWJH. Associations between sociodemographic, sampling and health factors and various cortisol indicators in a large sample without psychopathology. Psychoneuroendocrinology 2009;34:1109-20.

67. Bochdanovits Z, Verhage M, Smit AB, Geus EJ, Posthuma D, Boomsma DI, Penninx BW, Hoogendijk WJ, Heutink P. Joint reanalysis of 29 correlated SNPs supports the role of PCLO/Piccolo as a causal risk factor for major depressive disorder. Mol Psychiatry 2009;14:650-2.

68. Licht CM, de Geus EJ, van Dyck R, Penninx BW. Association between anxiety disorders and heart rate variability in the Netherlands Study of Depression and Anxiety (NESDA). Psychosom Med 2009;71:508-18.

69. Bet P, Penninx BW, Bochdanovitz Z, Uitterlinden AG, Beekman AT, van Schoor NM, Deeg DJ, Hoogendijk WJ. Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: New evidence for a gene-environment interaction. Am J

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Med Genet B Neuropsychiatr Genet. 2009;150B:660-9.

70. Ferrarini L, Veer IM, Baerends E, van Tol MJ, Renken RJ, van der Wee NJ, Veltman DJ, Aleman A, Zitman FG, Penninx BW, van Buchem MA, Reiber JH, Rombouts SA, Milles J. Hierarchical functional modularity in the resting-state human brain. Human Brain Mapp 2009;30:2220-31.

71. Pardo L, Bochdanovitz Z, de Geus E, Hottenga JJ, Sullivan P, Posthuma D, Penninx BWJH, Boomsma D, Heutink P. Global similarities with local differences in linkage disequilibrium between the Dutch and HapMap CEU populations. Eur J Hum Gen 2009;17:802-10.

72. Vreeburg SA, Hoogendijk WJ, van Pelt J, de Rijk RH, Verhagen JCM, van Dyck R, Smit JH, Zitman FG, Penninx BW. Major Depressive Disorder and Hypothalamic-pituitary-adrenal axis activity: Results from a large cohort study. Arch Gen Psychiatry 2009;66:617-626.

73. Milaneschi Y, Corsi AM, Penninx BW, Bandinelli S, Guralnik JM, Ferrucci L. IL-1RA and incident depressive symptoms over six years in older persons: The InCHIANTI study. Biol Psychiatry 2009;65:973-8.

74. Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Psychiatric GWAS Consortium Coordinating Committee including Penninx BW, Cichon S, Craddock N, Daly M, Faraone SV, Gejman PV, Kelsoe J, Lehner T, Levinson DF, Moran A, Sklar P, Sullivan PF. Am J Psychiatry 2009;166:540-56.

75. Vink JM, Smit AB, de Geus EJC, Sullivan P, Willemsen G, Hottenga JJ, Smit J, Hoogendijk W, Zitman FG, Peltonen L, Kaprio J, Pedersen N, Spector T, Ohm Kyvik K, Morley KI, Heath AC, Westendorp RGJ, Slagboom PE, Tiemeier H, Hofman A, Uitterlinden AG, Aulchenko YS, Amin N, van Duijn C, Penninx BW, Boomsma DI. Genome-wide association study of smoking initiation and persistence. Am J Hum Genetics 2009;84:367-79.

76. Rhebergen D, Beekman AT, Graaf RD, Nolen WA, Spijker J, Hoogendijk WJ, Penninx BW. The three-year naturalistic course of major depressive disorder, dysthymic disorder and double depression. J Affect Dis 2009;115:450-9.

77. Licht CM, de Geus E, Seldenrijk A, van Hout H, Zitman F, van Dyck R, Penninx BW. Depression is associated with decreased blood pressure but antidepressant use increases the risk for hypertension. Hypertension 2009;53:631-8.

78. Sullivan P, de Geus EJC, Willemsen G, James MR, Smit JH, Zandbelt T, Arolt V, Baune BT, Blackwood D, Cichon S, Coventry WL, Domschke K, Dumenil T, Farmer A, Fava M, Gordon SD, Heutink P, Holsboer F, Hoogendijk WJ, Hottenga JJ, Kohli M, Lin D, Lucae S, MacIntyre DJ, Maier W, McGhee KA, McGuffin P, Montgomery G, Muir WJ, Nolen W, Nöthen MM, Perlis R, Pirlo K, Posthuma D, Rietschel M, Schosser A, Smoller JW, AB Smit, Tzeng JY, van Dyck R, Zitman FG, Verhage M, Martin NG, Wray NR, Boomsma DI, Penninx BW. Genome-wide association for Major Depressive Disorder: a possible role for the protein PCLO. Mol Psychiatry 2009;14:359-75.

79. Cesari M, Kritchevsky SB. Atkinson HH, Penninx BW, Bari MD, Tracy RP, Pahor M. Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. Am Heart J 2009;157:334.e1-8.

80. Yaffe K, Lindquist K, Sen S, Cauley J, Ferrell R, Penninx BW, Harris T, Li R, Cummings SR. Estrogen receptor genotype and risk of cognitive impairment in elders: Findings from the Health ABC study. Neurobiol Aging 2009;30:607-14.

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81. Penninx BW, Nicklas BJ Newman AB, Harris TB, Goodpaster BH, Satterfield S, de Rekeneire N, Yaffe K, Pahor M, Kritchevsky SB. Metabolic syndrome and physical decline in older persons: results from the Health, Aging and Body Composition study. J Gerontol A Biol Sci Med Sci 2009;64A:96-102.

82. Cesari M, Kritchevsky SB, Newman AB, Simonsick EM, Harris TB, Penninx BWJH, Brach JS, Tylavsky FA, Satterfield S, Bauer DC, Rubin SM, Visser M, Pahor M. Added value of physical performance measures in predicting adverse health-related events. Results from the Health, Aging, and Body Composition Study. J Am Geriatr Soc 2009;57:251-9.

83. Verhaak PF, Prins MA, Spreeuwenberg P, Draisma S, van Balkom TJ, Bensing JM, Laurant MG, van Marwijk HW, van der Meer K, Penninx BW. Receiving treatment for common mental disorders. Gen Hosp Psychiatry 2009;31:46-55.

84. De Wit LM, van Straten A, van Herten M, Penninx BW, Cuijpers P. Depression and Body Mass Index, a U-shaped association. BMC Public Health 2009, 9:14

85. YS Aulchenko, S Ripatti, I Lindqvist, DI Boomsma, I Heid, C Pattaro, BWJH Penninx, ACJW Janssens, JF Wilson, I Rudan, Å Johansson, T Spector, NG Martin, NL Pedersen, M Falchi, JJ Hottenga, F Marroni, KO Kyvik, J Kaprio, A Hofman, P Elliott, C Gieger, G Willemsen, JH Smit, A Isaacs, C Hayward, V Vitart, I Jonasson, EJG Sijbrands, N Freimer, T Meitinger, AG Uitterlinden, J Saharinen, M Perola, JCM Witteman, PP Pramstaller, MR Jarvelin, U Gyllensten, H Campbell, A Wright, N Hastie, BA Oostra, EJC de Geus, F Kronenberg, MI McCarthy, CM van Duijn, L Peltonen. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts: Nat Genet. 2009;41:47-55.

86. Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. Variants in MTRN1B influence fasting glucose levels. Nat Genet. 2009;41:77-81.

87. Licht CM, de Geus EJ, Zitman FG, Hoogendijk WJ, van Dyck R, Penninx BW. Association between major depressive disorder and heart rate variability in the Netherlands Study of Depression and Anxiety (NESDA). Arch Gen Psychiatry 2008;65:1358-67.

88. Vogelzangs N, Kritchevsky SB, Beekman AT, Newman AB, Satterfield S, Simonsick EM, Yaffe K, Harris TB, Penninx BW. Depressive symptoms and change in abdominal obesity in older persons. Arch Gen Psychiatry 2008;65(12):1386-93.

89. de Wit MA, Tuinebreijer WC, Dekker J, Beekman AJ, Gorrissen WH, Schrier AC, Penninx BW, Komproe IH, Verhoeff AP. Depressive and anxiety disorders in different ethnic groups: A population based study among native Dutch and Turkish, Moroccan and Surinames

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migrants in Amsterdam. Soc Psychiatry Psychiatr Epid 2008; 43:905-12.

90. Knipscheer K, van Schoor NM, Penninx BW, Smit JH. Levenswaardering bij ouderen; de validering van een instrument [in Dutch]. Tijdschr Gerontol Geriatr 2008;39:133-145.

91. Penninx BW, Beekman AT, Smit JH, Zitman FG, Nolen WA, Spinhoven P, Cuijpers P, de Jong PJ, van Marwijk HWJ, Assendelft WJJ, van der Meer K, Verhaak P, Wensing M, de Graaf R, Hoogendijk WJ, Ormel J, van Dyck R. The Netherlands Study of Depression and Anxiety (NESDA): Rationale, objectives and methods. Int J Meth Psychiatr Res 2008;17:121-140.

92. Plaisier I, de Bruijn J, Smit J, de Graaf R, Ten Have M, van Dyck R, Penninx BW. The effect of social roles on mental health: a matter of quantity or quality? J Affect Dis 2008;105:63-72.

93. Mast BT, Miles T, Penninx BW, Yaffe K, Rosano C, Satterfield S, Ayonayon H, Harris T, Simonsick E. Vascular disease and longitudinal risk for elevated depressive symptoms in older adults: Findings from Health ABC. Biol Psychiatry 2008;15;64:320-6.

94. Lamers F, Jonkers CC, Bosma H, Penninx BW, Knottnerus JA, van Eijk JT. Summed score of the Patient Health Questionnaire-9 was a reliable and valid method for depression screening in chronically ill elderly patients. J Clin Epidemiol. 2008;61:679-87.

95. Wouts L, OudeVoshaar RC, Bremmer MA, Buitelaar JK, Penninx BW, Beekman AT. Cardiac disease, depressive symptoms and incident stroke in an elderly population. Arch Gen Psychiatry 2008;65:596-602.

96. Hoogendijk WJ, Lips P, Dik MG, Deeg DJ, Lips P, Beekman AT, Penninx BW. Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults. Arch Gen Psychiatry 2008;65:508-12.

97. You T, Nicklas BJ, Ding J, Penninx BW, Goodpaster BH, Bauer DC, Tylavsky FA, Harris TB, Kritchevsky SB. The Metabolic Syndrome is Associated with Circulating Adipokines in Older Adults across a Wide Range of Adiposity. J Gerontol Med Sci 2008;63:414-419.

98. Wiersma JE, van Schaik DJ, van Oppen P, McCullough JP, Schoevers RA, Dekker JJ, Blom MB, Maas K, Smit JH, Penninx BW, Beekman AT. Treatment of chronically depressed patients: a multisite randomized controlled trial testing the effectiveness of 'Cognitive Behavioral Analysis System of Psychotherapy' (CBASP) for chronic depressions versus usual secondary care. BMC Psychiatry 2008;8:18.

99. Boomsma DI, Willemsen G, Sullivan PF, Heutink P, Meijer P, Sondervan D, Kluft C, Smit G, Nolen WA, Zitman FG, Smit JH, Hoogendijk WJ, van Dyck R, de Geus EJ, Penninx BW. Genome-wide association for Major Depression: Description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects. Eur J Hum Genet 2008;16:335-42.

100. Brenes GA, Penninx BW, Judd PH, Rockwell E, Sewell DD, Wetherell JL. Anxiety, depression and disability across the lifespan. Aging Ment Health 2008;12:158-63.

101. Bremmer MA, Beekman AT, Deeg DJ, Penninx BW, Dik MG, Hack DE, Hoogendijk WJ. Inflammatory markers in late-life depression: Results from a population-based study. J Affect Disord 2008;106:249-55.

102. Plaisier I, de Bruijne J, Smit JH, de Graaf R, Ten Have M, Beekman AT, van Dyck R, Penninx BW. Work and family roles and the association with depressive and anxiety disorders: Differences between men and women. J Affect Disord 2008;105:63-72.

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103. Schaap LA, Pluijm SM, Deeg DJ, Penninx BW, Nicklas BJ, Lips P, Harris TB, Newman AB, Kritchevsky SB, Cauley JA, Goodpaster BH, Tylavsky FA, Yaffe K, Visser M. Low testosterone levels and decline in physical performance and muscle strength in older men: findings from two prospective cohort studies. Clin Endocrinol 2008;68:42-50.

104. Koster A, Penninx BW, Newman AB, Visser M, van Gool CH, Harris TB, van Eijk JThM, Kempen GIJM, Brach JS, Simonsick EM, Houston DK, Tylavsky FA, Rubin SM, Kritchevsky SB. Lifestyle factors and incident mobility limitation in obese and non-obese older adults. Obesity 2007;15:3122-32.

105. Morsink LF, Vogelzangs N, Nicklas BJ, Beekman AT, Satterfield S, Rubin SM, Yaffe K, Simonsick E, Newman AB, Kritchevsky SB, Penninx BW. Associations between sex steroid hormone levels and depressive symptoms in elderly men and women: Results from the Health ABC study. Psychoneuroendocrinology 2007;32:874-83.

106. Hermens MLM, van Hout HPJ, Terluin B, Ader JH, Penninx BWJH, van Marwijk HWJ, Bosmans JE, van Dyck R, de Haan M. Clinical effectiveness of usual care with or without antidepressant medication for primary care patients with minor or mild-major depression: a randomized equivalence trial. BMC Medicine 2007;5(1):36.

107. Penninx BW. Urinary Cortisol Level and Urine Volume. Am J Geriatr Psychiatry 2007;15:985-986

108. Dik MG, Jonker C, Comijs H, Deeg DJ, Kok A, Yaffe K, Penninx BW. The metabolic syndrome, inflammation, and cognition. Diabetes Care 2007;30:2655-60.

109. Bremmer MA, Deeg DJH, Beekman ATF, Penninx BWJH, Lips P, Hoogendijk W. Major Depression in Late Life Is Associated with Both Hypo- and Hypercortisolemia. Biol Psychiatry 2007;62:479-86.

110. Vogelzangs N, Penninx BW. Cortisol and insulin in depression and metabolic syndrome.Psychoneuroendocrinology 2007;32:856.

111. Penninx BW, Beekman AT, Bremmer M, Hoogendijk W, Bandinelli S, Lauretani F, Guralnik J, Ferrucci L. Late-Life Depressive Symptoms Are Associated With Both Hyperactivity and Hypoactivity of the Hypothalamo-Pituitary-Adrenal Axis. Am J Geriatr Psychiatry 2007;15:522-529.

112. Maraldi C, Volpato S, Penninx BW, Yaffe K, Simonsick EM, Strotmeyer ES, Cesari M, Kritchevsky SB, Perry, S, Ayonayon HN, Pahor M. Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study. Arch Intern Med 2007;167:1137-44.

113. van Gool CH, Kempen GI, Penninx BW, Deeg DJ, van Eijk JTh. Chronic disease and lifestyle transitions: Results from the Longitudinal Aging Study Amsterdam. J Aging Health 2007;19:416-38.

114. Vogelzangs N, Beekman AT, Kritchevsky SB, Newman AB, Pahor M, Yaffe K, Rubin SM, Harris, TB, Satterfield S, Simonsick EM, Penninx BW. Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the health, aging and body composition study. J Gerontol A Biol Sci Med Sci. 2007;62:563-9.

115. Penninx BW, Woodman R, Cohen HJ. Anemia and cancer in old age. J Support Oncol 2007;5:107-113.

116. Vogelzangs N, Suthers K, Ferrucci L, Simonsick EM, Ble A, Schrager M, Bandinelli S,

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Lauretani F, Gianelli SV, Penninx BW. Hypercortisolemic depression is associations with the metabolic syndrome in late-life. Psychoneuroendocrinology 2007;32:151-9.

117. Brenes GA, Kritchevsky S, Mehta K, Ayonayon H, Rosano C, Rubin S, Satterfield S, Simonsick EM, Yaffe K, Penninx BWJH. Scared to death: results from the Health, Aging and Body Composition Study. Am J Geriatr Psych 2007;15:262-265.

118. Plaisier I, de Bruijn JGM, Smit JH, de Graaf R, ten Have M, van Dyck R, Beekman AT, Penninx BW. The contribution of working conditions and social support to the onset of affective disorders among male and female employees. Soc Sci Med 2007;64:401-10.

119. Yaffe K, Barnes D, Lindquist K, Cauley J, Simonsick EM, Penninx BW, Satterfield S, Harris T, Cummings SR. Endogenous sex hormone levels and risk of cognitive decline in an older biracial cohort. Neurobiol Aging 2007;28:171-8.

120. Brenes G, Williamson J, Messier S, Rejeski J, Pahor M, Penninx BW. Treatment of minor depression in older adults: A pilot study comparison of sertraline and exercise. Aging Ment Health 2007;11:61-8.

121. Mangani R, Cesari M, Kritchevsky SB, Maraldi C, Carter SC, Atkinson HH, Penninx BW, Marchionni N, Pahor M. Physical exercise and comorbidity. Results from the Fitness and Arthritis in Seniors Trial (FAST). Aging Clin Exp Res 2006;18:374-80.

122. Schalk BMW, Visser M, Bremmer MM, Penninx BWJH, Bouter LM, Deeg DJH. Change of serum albumin and risk of cardiovascular disease and all-cause mortality in the Longitudinal Aging Study Amsterdam. Am J Epidemiol 2006;164:969-77.

123. Koster A, Bosma H, Kempen GI, Penninx BW, Beekman AT, Deeg DJ, van Eijk JT. Socio-economic differences in incident depression in older adults: The role of psychosocial factors, physical health status, and behavioral factors. J Psychosom Res 2006;61:619-27.

124. Figaro MK, Kritchevsky SB, Resnick HE, Shorr RI, Butler J, Shintani A, Penninx BW, Simonsick EM, Goodpaster BH, Newman AB, Schwartz AV, Harris TB. Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) study. Diabetes Care 2006;29:2039-45.

125. Koster A, Bosma H, Kempen G, Penninx BW, Deeg DJ, Broese-Groenou M, van Eijk JT. The explanation of socio-economic differences in changes of physical function in older adults: results from the Longitudinal Aging Study Amsterdam. BMC Public Health 2006;6(1):244.

126. Hesselink AE, van der Windt DAWM, Penninx BWJH, Wijnhoven HAH, Twisk JWR, Bouter LM, van Eijk JThM. What predicts change in pulmonary function and quality of life in patients with asthma or COPD in primary care? J Asthma 2006;43:513-9.

127. Schaik A van, van Marwijk HWJ, Ader H, van Dyck R, de Haan M, Penninx BW, van Hout H, Kooy K van der, Beekman AT. Interpersonal psychotherapy for elderly patients in primary care. Am J Geriatr Psychiatry 2006;14:777-86.

128. Terluin B, van Marwijk HW, de Vet HC, Ader JH, Penninx BW, Hermens ML, van Balkom TJ, van der Klink JJ, Stalman WB. The four-dimensional symptom questionnaire (4DSQ): A new self-report questionnaire to assess distress, depression, anxiety and somatization. BMC Psychiatry 2006;6:34

129. Penninx BW. Response to dr. Cheng. J Am Geriatr Soc 2006;54:1298.

130. van Gool CH, Penninx BWJH, Kempen GIJM, Rejeski WJ, Miller GD, van Eijk JThM, Pahor

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M, Messier SP. Determinants of session attendance to diet and exercise interventions. Results from the Arthritis, Diet and Activity Promotion Trial. Contemp Clin Trials. 2006;27:227-37.

131. Penninx BWJH, Pahor M, Woodman RC, Guralnik JM. Anemia in old age is associated with increased mortality and hospitalization. J Gerontol: Med Sci 2006;61:474-9.

132. Koster A, Bosma H, Penninx BW, Kritchevsky S, Kempen GI, van Eijk JT, Krtichevsky SB. Association of inflammatory markers and socioeconomic status. J Gerontol Med Sci 2006;61:284-90.

133. Nicklas BJ, Cesari M, Kitzman D, Penninx BW, Kritchevsky S, Newman AB, Jingzhong D, Pahor M, Harris TB. Abdominal adiposity is an independent risk factor for congestive heart failure in older men and women: The Health, Aging and Body Composition Study. J Am Geriatr Soc 2006;54:413-20.

134. Eisenstadt R, Penninx BW, Woodman R. Anemia in the elderly: Current understanding and emerging concepts. Blood Rev 2006;20:213-26.

135. Gray SL, LaCroix AZ, Hanlon JT, Penninx BWJH, Blough DK, Leveille SG, Arts MB, Guralnik JM, Buchner DM. Benzodiazepine use and physical disability in community-dwelling older adults. J Am Geriatr Soc 2006;54:224-230.

136. Koster A, Penninx BWJH, Bosma H, Kempen GI, Newman AB, Rubin SM, Satterfield S, Atkinson HH, Ayonayon HN, Rosano C, Yaffe K, Harris TB, Rooks RN, van Eijk JT, Kritchevsky SB. Socioeconomic differences in cognitive decline and the role of biomedical factors. Ann Epidemiol. 2005;15:564-71.

137. Penninx BW, Pluijm S, Lips P, Woodman R, Miedema K, Guralnik JM, Deeg DJ. Anemia is associated with increased risk of recurrent falls. J Am Geriatr Soc 2005;53:2106-11.

138. Schalk BMW, Visser M, Penninx BWJH, Baadenhuijsen H, Bouter LM, Deeg DJH. Change in serum albumin and subsequent decline in functional status in older persons. Aging: Clin Exp Res 2005;17:297-305.

139. Cesari M, Kritchevsky SB, Nicklas BJ, Penninx BWJH, Holvoet P, Koh-Banerjee P, Cummings SR, Harris TB, Newman AB, Pahor M. Lipoprotein peroxidation and mobility limitation: results from the health, aging and body composition study. Arch Intern Med 2005;165:2148-54.

140. Koster A, Penninx BWJH, Bosma H, Kempen GI, Harris TB, Newman AB, Rooks RN, Rubin SM, Simonsick EM, van Eijk JThM, Kritchevsky SB. Is there a biomedical explanation for socio-economic differences in incident mobility limitation? J Gerontol Med Sci 2005;60:1022-7.

141. Cesari M, Kritchevsky SB, Penninx BW, Nicklas BJ, Simonsick EM, Newman AB, Tylavsky FA, Brach JS, Satterfield S, Bauer DC, Visser M, Rubin SM, Harris TB, Pahor M. Prognostic value of usual gait speed in well-functioning older people. Results from the Health, Aging and Body Composition Study. J Am Geriatr Soc 2005;53:1675-80.

142. Onder G, Penninx BWJH, Cesari M, Bandinelli S, Lauretani F, Bartali B, Pahor M, Ferrucci L. Anemia is associated with depression in older adults: results from the InChianti study. J Gerontol Med Sci 2005;60:1168-72.

143. Foy CG, Penninx BWJH, Shumaker SA, Messier SP, Pahor M. Long-term exercise therapy resolves ethnic differences in baseline health status in older adults with knee osteoarthritis.

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J Am Geriatr Soc 2005;53:1469-75.

144. Atkinson HH, Cesari M, Kritchevsky SB, Penninx BWJH, Fried LP, Guralnik JM, Williamson JD. Predictors of combined cognitive and physical decline. J Am Geriatr Soc 2005;53:1197-202.

145. Cesari M, Kritchevsky SB, Baumgartner RN, Atkinson HH, Penninx BW, Lenchik L, Palla SL, Ambrosius WT, Tracy RP, Pahor M. Sarcopenia, obesity, and inflammation – results from the Trial of Angiotension-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. Am J Clin Nutr 2005;82:428-434.

146. Kritchevsky SB, Nicklas BJ, Visser M, Simonsick EM, Newman AB, Harris TB, Lange E, Penninx BW, Goodpaster BH, Satterfield S, Colbert LH, Rubin SM, Pahor M. Angiotensin-converting enzyme insertion/deletion genotype, exercise and physical decline. JAMA 2005;294:691-698.

147. Schalk BMW, Deeg DJH, Penninx BWJH, Bouter LM, Visser M. Serum albumin and grip strength: a longitudinal study in older men and women. J Am Geriatr Soc 2005;53:1331-1338.

148. Cesari M, Penninx BWJH, Lauretani F, Russo R, Bartali B, Pahor M, Ferrucci L. Bone density and hemoglobin levels in older persons: results from the InChianti study. Osteoporosis International 2005;16:691-699.

149. Onder G, Penninx BWJH, Ferrucci L, Fried LM, Guralnik JM, Pahor M. Measures of physical performance and risk of progressive and catastrophic disability: Results from the Women’s Health and Aging Study. J Gerontol: Med Sci 2005:60:74-79.

150. Nicklas BJ, Penninx BWJH, Cesari M, Kritchevsky SB, Newman AB, Kanaya AM, Pahor M, Jingzhong D, Harris TB. Association of visceral adipose tissue with incident myocardial infarction in older men and women: The Health, Aging and Body Composition study. Obstet Gynecol Surv. 2005;60:173-175.

151. van Gool CH, Penninx BWJH, Kempen GIJM, Rejesk WJi, Miller GD, van Eijk JThM, Pahor M, Messier SP. Effects of exercise adherence on physical function among overweight older adults with knee osteoarthritis. Arthritis Rheum. 2005;53:24-32.

152. Brenes GA, Guralnik JM, Williamson J, Fried LP, Penninx BWJH. Correlates of anxiety symptoms in physically disabled older women. Am J Geriatr Psychiatr 2005;13:15-22.

153. van Gool CH, Kempen GIJM, Penninx BWJH, Deeg DJH, Beekman ATF, van Eijk JThM. Impact of depression on disablement in late middle aged and older persons. Results from the Longitudinal Aging Study Amsterdam. Soc Sci Med 2005;60:25-36.

154. Brenes GA, Williamson J, Guralnik JM, Fried LP, Penninx BWJH. The influence of anxiety on the development of disability. J Am Geriatr Soc 2005;53:34-39.

155. Hesselink AE, Penninx BWJH, van der Windt DAWM, van Duin BJ, de Vries P, Twisk JW, Bouter LM, van Eijk JThM. Effectiveness of an education programme by a general practice assistant for asthma and COPD patients: results from a randomised controlled trial. Pat Educ Counsel 2004;55:121-128.

156. Beekman ATF, Geerlings SW, Deeg DJH, Smit JH, Schroevers RA, de Beurs E, Braam AW, Penninx BWJH, van Tilburg W. Het beloop van depressie bij ouderen: resultaten van 6 jaar intensieve follow-up. Tijdschrift voor Psychiatrie 2004;46:73-83.

157. Nicklas BJ, Penninx BWJH, Cesari M, Newman A, Kritchevsky SB, Newman AB, Kanaya

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AM, Pahor M, Jingzhong D, Harris TB. Association of visceral adipose tissue with incident myocardial infarction in older men and women: The Health, Aging and Body Composition study. Am J Epidemiol 2004;160:741-9.

158. Penninx BWJH, Abbas H, Ambrosius WA, Davis C, Nicklas B, Messier S, Pahor M. Markers of inflammatory markers and function among obese older persons with knee osteoarthritis. J Rheumatology 2004;31:2027-2031.

159. Phelan EA, Williams B, Penninx BWJH, Lo Gerfo J, Leveille SG. ADL Function and disability in older adults in a randomized trial of the health enhancement program. J Gerontol: Med Sci 2004;59:M838-43.

160. Penninx BWJH, Kritchevsky SB, Newman AB, Nicklas BJ, Simonsick EM, Rubin S, Nevitt M, Visser M, Harris T, Pahor M. Inflammatory markers and incident mobility limitation: Results from the Health ABC study. J Am Geriatr Soc 2004;52:1105-13.

161. Rolland Y, Cesari M, Miller ME, Penninx BWJH, Atkinson HH, Pahor M. Reliability of the 400-m usual-pace walk test as an assessment of mobility limitation in older adults. J Am Geriatr Soc 2004;52:972-6.

162. Ferrucci L, Guralnik JM, Studenski S, Fried LP, Cutler GB Jr, Walston JD: Interventions on Frailty Working Group (including Penninx BWJH). Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: A consensus report. J Am Geriatr Soc 2004; 52:625-34.

163. Penninx BWJH, Pahor M, Cesari M, Corsi AM, Woodman R, Bandinelli S, Guralnik JM, Ferrucci L. Anemia is associated with decreased physical performance and muscle strength. J Am Geriatr Soc 2004:52:719-724.

164. Nicklas, BJ, Ambrosius W, Messier SP, Miller GD, Penninx BWJH, Loeser RF, Palla S, Bleecker E, Pahor M. Dietary-induced weight loss, exercise and chronic inflammation in older, obese adults: A randomized controlled clinical trial. Am J Clin Nutr 2004;79:544-551.

165. Cesari M, Penninx BWJH, Lauretani F, Russo CS, Carter C, Baldinelli S, Atkinson H, Onder G, Pahor M, Ferrucci L. Hemoglobin levels and skeletal muscle: Results from the InCHIANTI Study. J Gerontol: Med Sci 2004;59:M249-M254.

166. Cesari M, Penninx BWJH, Pahor M, Lauretani F, Corsi AM, Williams GR, Guralnik JM, Ferrucci L. Inflammatory markers and physical performance in older persons: the InCHIANTI Study. J Gerontol: Med Sci 2004;59:M242-M248.

167. Cesari M, Pahor M, Bartali B, Cherubin A, Penninx BWJH, Williams GR, Atkinson H, Martin A, Guralnik J, Ferrucci L. Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti (InCHIANTI) study. Am J Clin Nutr 2004:79:289-294.

168. Hesselink AE, Penninx BWJH, Schlosser M, Wijnhoven HAH, van der Windt DAWM, van Eijk JThM. The role of coping resources and coping style in quality of life of patients with asthma and COPD. Qual Life Res 2004;13:509-518.

169. Cesari M, Penninx BWJH, Newman AB, Kritchevsky SB, Nicklas BJ, Sutton-Tyrrell K, Tracy RP, Rubin SM, Harris TB, Pahor M. Inflammatory markers and the onset of cardiovascular disease: results from the Health ABC study. Circulation 2003;108:2317-2322.

170. Gray SL, Penninx BWJH, Blough DK, Artz MB, Guralnik JM, Wallace RB, Buchner DM, LaCroix AZ. Benzodiazepine use and physical performance in community-dwelling older women. J Am Geriatr Soc 2003;51:1563-1570.

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171. Onder G, Penninx BWJH, Guralnik JM, Jones H, Fried LP, Pahor M, Williamson J. Sexual satisfaction and risk of disability among older women. J Clin Psychiatry 2003;64:1177-82.

172. Schoevers RA, Geerlings MI, Beekman ATF, Penninx BWJH, Deeg DJH, Jonker C, van Tilburg W. De relatie tussen depressie, sekse en verhoogde mortaliteit bij thuiswonende ouderen. De AMSTEL-studie (Amsterdam Study of The Elderly). Tijdsch v Psychiatr 2003; 45:479-493.

173. Cesari M, Penninx BWJH, Newman AB, Kritchevsky SB, Nicklas BJ, Sutton-Tyrrell K, Tracy RP, Rubin SM, Harris TB, Pahor M. Inflammatory markers and cardiovascular disease: the Health, Aging and Body Composition [Health ABC] study). Am J Cardiol 2003;92:522-528.

174. Yaffe K, Lindquist K, Penninx BW, Simonsick EM, Pahor M, Kritchevsky S, Launer L, Kuller L, Rubin S, Harris T. Inflammatory markers and cognition in well-functioning African-American and white elders. Neurology 2003;61:76-80.

175. Penninx BWJH, Guralnik J, Wallace R, Onder G, Ferrucci L, Pahor M. Anemia and physical decline in older persons. Am J Med 2003;115:104-110.

176. Nicklas BJ, Penninx BWJH, Ryan AS, Berman DM, Lynch NA, Dennis KE. Visceral adipose tissue cutoffs associated with metabolic risk factors for coronary heart disease in women.Diabetes Care 2003;26:1413-1420.

177. Penninx BWJH, Kritchevsky SB, Yaffe K, Newman AB, Simonsick EM, Rubin S, Ferrucci L, Harris T, Pahor M. Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study. Biol Psychiatry 2003;54:566-72.

178. Broese van Groenou MI, Deeg DJH, Penninx BWJH. Income differentials in functional disability in old age: relative risks of onset, recovery, decline, attrition and mortality. Aging Clin Exp Res 2003;15:174-83.

179. Bisschop MI, Kriegsman DMW, van Tilburg TG, Penninx BWJH, van Eijk JThM, Deeg DJH. The influence of differing social ties on decline in physical functioning among older people with and without chronic diseases: the Longitudinal Aging Study Amsterdam. Aging Clin Exp Res 2003;15:164-73.

180. Gool van CH, Kempen GIJM, Penninx BWJH, Deeg DJH, Beekman ATF, van Eijk THM. Relationship between changes in depressive symptoms and unhealthy lifestyles in late middle aged and older persons. Results from the Longitudinal Aging Study Amsterdam. Age and Aging 2003;32:81-7.

181. Weeks SK, McGann P, Michaels TK, Penninx BWJH. Comparing short versions of the Geriatric Depression Scale leads to the GDS5/15. J Nursing Scholarship 2003;35:133-137.

182. Mehta KM, Simonsick EM, Penninx BWJH, Schulz R, Rubin SM, Satterfield S, Yaffe K. Prevalence and correlates of anxiety symptoms in well-functioning older adults: findings from the Health Aging and Body Composition study. JAGS 2003;51:499-504.

183. Ferrucci L, Penninx BWJH, Volpato S, Harris TB, Bandeen-Roche K, Balfour J, Leveille SG, Fried L, Guralnik JM. Change in muscle strength explains accelerated decline in physical function in older women with high interleukin-6 serum levels. JAGS 2002;50:1947-54.

184. Onder G, Penninx BWJH, Landi F, Atkinson H, Cesari M, Bernabei R, Pahor M. Depression and adverse drug reactions among hospitalized older adults. Arch Int Med 2003;163:301-5.

185. Rejeski WJ, Focht BC, Messier SP, Morgan T, Pahor M, Penninx B. Obese, older adults

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with knee osteoarthritis: weight loss, exercise and quality of life. Health Psychology 2002: 21:419-26.

186. Onder G, Penninx BWJH, Pahor M. ACE inhibitors use and physical performance - Authors' reply. Lancet 2002;360:1099-1100.

187. Beekman ATF, Geerlings SW, Deeg DJH, Schoevers RS, de Beurs E, Braam AW, Penninx BWJH, van Tilburg W. The natural history of late-life depression: a 6-year, 14-wave prospective study in the community. Arch Gen Psychiatry 2002;59:605-11.

188. Onder G, Penninx BWJH, Lapuerta P, Fried LP, Chaves PHM, Ostir G, Guralnik JM, Pahor M. Change in physical performance over time in older women: the Women’s Health and Aging Study. J Gerontol: Med Sci 2002;57:M289-93.

189. Beekman ATF, Penninx BWJH, Deeg DJH, de Beurs E, Geerling SW, van Tilburg W. The impact of depression on the well-being, disability and use of services in older adults: a longitudinal perspective. Acta Psychiatr Scand 2002;105:20-27.

190. Di Bari M, Pahor M, Barnard M, Gades N, Graney M, Franse LV, Penninx BWJH, Marchionni N, Applegate WB. Evaluation and correction for a “training effect” in the cognitive assessment of older adults. Neuroepidemiology 2002;21:87-92.

191. Van der Windt DAWM, Croft PR, Penninx BWJH. Neck and upper limb pain: more pain is associated with psychological distress and consultation rates in primary care. J Rheumatol 2002;29:564-9.

192. Onder G, Penninx BWJH, Balkrishnan R, Fried LP, Chaves PHM, Williamson JD, Carter C, Di Bari M, Guralnik JM, Pahor M. Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet 2002;359:926-30.

193. Penninx BWJH, Rejeski J, Messier SP, Pandya J, Miller M, DiBari M, Applegate W, Pahor M. Exercise and depressive symptoms: A comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology. J Gerontol: Psych Sci 2002;57:P124-P132.

194. Ferrucci LM, Furberg CA, Penninx BWJH, DiBari M, Guralnik JM, Chen JG, Applegate WB, Pahor M. Treatment of systolic hypertension in older patients: who should be treated more aggressively? Circulation 2001;104:1923-6.

195. Penninx BWJH, Messier SP, Rejeski J, Williamson JD, DiBari M, Morgan T, Applegate W, Pahor M. Physical exercise and prevention of ADL disability in older osteoarthritis patients. Arch Int Med 2001:161;2309-2316.

196. Hesselink AE, Penninx BWJH, Wijnhoven HAH, Kriegsman DMW, van Eijk JThM. Determinants of incorrect inhalation technique in patients with astma and COPD. Scand J Prim Care 2001;19:255-260.

197. Penninx BWJH, Beekman ATF, Deeg DJH. Cognitive impairment with chronic disease in depression and mortality. Reply to Dr. Gledhills’ letter to the editor. Arch Gen Psychiatr 2001;58:306-307.

198. Penninx BWJH, Beekman ATF, Honig A, Deeg DJH, Schoevers RA, van Eijk JThM, van Tilburg W. Effect of depression on cardiac mortality. Results from a community-based longitudinal study. Arch Gen Psychiatr 2001;58:221-227.

199. Rantanen T, Guralnik JM, Ferrucci L, Penninx BWJH, Leveille SG, Sipila S, Fried LP.

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Coimpairments as predictors of severe walking disability in older women. J Am Geriatr Soc 2001;49:21-27.

200. Wijnhoven HAH, Kriegsman DMW, Hesselink AE, Penninx BWJH, de Haan M. Determinants of different dimensions of disease severity in asthma and COPD: pulmonary function and health-related quality of life. Chest 2001;119:1034-42.

201. Penninx BWJH, Guralnik JM, Stabler S, Ferrucci L, Fried LP. Vitamin B12 deficiency and depression: Epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry 2000;157:715-721.

202. Leveille SG, Penninx BWJH, Melzer D, Izmirlian G, Guralnik JM. Sex differences in the prevalence of mobility disability in old age: the dynamics of incidence, recovery and mortality. J Gerontol: Soc Sci 2000;55:41-50.

203. Rantanen T, Penninx BWJH, Masaki K, Lintunen T, Foley D, Guralnik JM. Depressed mood and body mass index as predictors of muscle strength decline in old men. J Am Geriatr Soc 2000;48:613-7.

204. Penninx BWJH, Ferrucci L, Leveille SG, Rantanen T, Pahor M, Guralnik JM. Lower extremity performance in nondisabled older persons as a predictor of subsequent hospitalization. J Gerontol: Med Sci 2000;55:M691-M697.

205. Schoevers RA, Geerlings MI, Beekman ATF, Penninx BWJH, Deeg DJH, Jonker C, van Tilburg W. Association of depression and gender with mortality in old age. Results from the Amsterdam Study of the Elderly (AMSTEL). Br J Psychiatry 2000;177:336-342.

206. Penninx BWJH, Guralnik JM, Bandeen-Roche K, Kasper JD, Simonsick EM, Ferrucci L, Fried LP. The protective effect of emotional vitality on adverse health outcomes in disabled older women. J Am Geriatr Soc 2000;48:1359-1366.

207. Ferrucci L, Penninx BWJH, Leveille S, Corti M, Pahor M, Wallace R, Harris TB, Havlik RJ, Guralnik JM. Characteristics of non-disabled older persons who perform poorly in objective tests of lower extremity function. J Am Geriatr Soc 2000;48:1102-1110.

208. Penninx BWJH, Beekman ATF, Deeg DJH, van Tilburg W. Lichamelijke achteruitgang en depressie bij oudere mannen en vrouwen: longitudinale resultaten van het LASA onderzoek. [in Dutch, Physical health consequences of late-life depression: results from the Longitudinal Aging Study Amsterdam]. Tijdschr Geront Geriatr 2000;31:211-218.

209. Penninx BWJH, Deeg DJH, van Eijk JThM, Beekman ATF, Guralnik JM. Changes in depression and physical function in older persons: A longitudinal perspective. J Affect Dis 2000:61:1-12.

210. Hoek F, Penninx BWJH, Ligthart G, Ribbe M. Health care for older persons, a country profile: The Netherlands. J Am Geriatr Soc 2000;48:214-7.

211. Penninx BWJH. A happy person, a healthy person? [editorial]. J Am Geriatr Soc 2000;48:590-592.

212. Kasper JD, Shore A, Penninx BWJH. Caregiving arrangements of older disabled women, caregiving preferences, and views on adequacy of care. Aging: Clin Exp Res 2000;12:141-53.

213. Penninx BWJH, T van Tilburg, DMW Kriegsman, AJP Boeke, DJH Deeg, JThM van Eijk. Social network, social support and loneliness in older persons with different chronic diseases. J Aging & Health 1999;11:151-168.

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214. Guralnik JM, Ferrucci L, Penninx BWJH, Kasper JD, Leveille S, Bandeen-Roche K, Fried LP. New and worsening conditions and change in physical and cognitive performance during weekly interventions over six months: The Women's Health and Aging Study. J Gerontol: Med Sci 1999; 54:410-420.

215. Geerlings MI, Deeg DJH, Penninx BWJH, Schmand B, Jonker C, Bouter LM, van Tilburg W. Cognitive reserve and mortality in dementia: the role of cognition, functional ability and depression. Psychol Med 1999,29:1219-1226.

216. Penninx BWJH, Guralnik JM, Leveille S, Ferrucci L, van Eijk JThM. Exploring the effect of depression on physical disability: longitudinal evidence from the Established Populations for Epidemiologic Studies of the Elderly. Am J Public Health 1999;89:1346-1352.

217. Penninx BWJH, Guralnik JM. Chronically depressed mood and cancer risk in older persons. Response. Letter to the Editor. J Natl Cancer Inst 1999;91:804.

218. Penninx BWJH, Guralnik JM. Chronically depressed mood and cancer risk in older persons. Response. Letter to the Editor. J Natl Cancer Inst 1999;91:1080-1081.

219. Ferrucci L, Harris TB, Guralnik JM, Tracy RP, Corti MC, Cohen JH, Penninx B, Pahor M, Wallace R, Havlik RJ. Serum Il-6 and the development of disability in older persons. J Am Geriatr Soc 1999;47:639-646.

220. Penninx BWJH, Geerlings SW, Deeg DJH, van Eijk JThM, van Tilburg W, Beekman ATF. Minor and major depression and the risk of death in older persons. Arch Gen Psychiatry 1999;56:889-896.

221. Comijs HC, Penninx BWJH, Knipscheer CPM, van Tilburg W. Psychological distress in victims of elder mistreatment: the effects of social support and coping. J Gerontol: Psychol Sci 1999;54:240-246.

222. Pahor M, Guralnik JM, Wan J, Ferrucci L, Penninx BWJH, Lyles A, Ling S. Lower body osteoarticular pain and dose of analgesic medications: the Women's Health and Aging Study (WHAS). Am J Public Health 1999;89:930-934.

223. Stabler SP, Allen RH, Fried LF, Pahor M, Kittner SJ, Penninx BWJH, Guralnik JM. Racial differences in prevalence of cobalamin and folate deficiency in disabled elderly women. Am J Clin Nutr 1999;70:911-919.

224. Penninx BWJH, Guralnik JM, Mendes de Leon CF, Pahor M, Visser M, Corti M, Wallace RB. Cardiovascular events and mortality in newly and chronically depressed persons 70 years of age. Am J Cardiol 1998;81:988-1994.

225. Ferrucci L, Guralnik JM, Penninx BWJH, Leveille S. Cigarette smoking exposure and hearing loss. Letter to the Editor. JAMA 1998;280:963-964.

226. Penninx BWJH, Guralnik JM, Ferrucci L, Simonsick EM, Deeg DJH, Wallace RB. Depressive symptoms and physical decline in community-dwelling older persons. JAMA 1998;279:1720-1726.

227. Penninx BWJH, Guralnik JM, Simonsick EM, Kasper JD, Ferrucci L, Fried LP. Emotional vitality among older disabled women: the Women’s Health and Aging Study. J Am Geriatr Soc 1998;46:807-815.

228. Penninx BWJH, Tilburg TG van, Kriegsman DMW, Deeg DJH, Boeke AJP, Eijk JThM van. Effects of social support and personal coping resources on depressive symptoms: Different for various chronic diseases? Health Psychol 1998;17:551-558.

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229. Penninx BWJH, Guralnik JM, Pahor M, Ferrucci L, Cerhan JR. Wallace RB, Havlik RJ. Chronic depressed mood associated with elevated cancer risk in older persons. J Natl Cancer Inst 1998;90:1888-93.

230. Beekman ATF, Penninx BWJH, Deeg DJH, Ormel J, Smit JH, Braam AW, van Tilburg W. Depression in survivors of stroke: a community-based study of prevalence, risk factors and consequences. Soc Psychiatr Psych Epidemiol 1998;33:463-470

231. Kriegsman DMW, Penninx BWJH, Deeg DJH, Boeke AJP, Eijk JThM van. Does family support mitigate the impact of specific chronic diseases on mobility in community-dwelling elderly? Disab & Rehab 1997;19:71-83.

232. Beekman ATF, Penninx BWJH, Deeg DJH, Ormel J, Braam A, van Tilburg W. Depression and physical health in later life: results from the Longitudinal Aging Study Amsterdam (LASA). J Affect Dis 1997;46:219-231.

233. Kriegsman DMW, Deeg DJH, Eijk JThM van, Penninx BWJH, Boeke AJP. Do disease specific characteristics add to the explanation of mobility limitations in patients with different chronic diseases? A study in the Netherlands. J Epidemiol & Comm Health 1997;51:676-85.

234. Penninx BWJH, Tilburg TG van, Deeg DJH, Kriegsman DMW, Boeke AJP, Eijk JThM van. Direct and buffer effects of social support and personal coping resources in patients with arthritis. Soc Sci & Med 1997;44:393-402.

235. Penninx BWJH, Tilburg TG van, Kriegsman DMW, Deeg DJH, Boeke AJP, Eijk JThM van. Effects of social support and personal coping resources on mortality in older age: The Longitudinal Aging Study Amsterdam. Am J Epidemiol 1997;146:510-19.

236. Ormel J, Kempen GIJM, Penninx BWJH, Brilman EJ, Beekman ATF, van Sonderen E. Chronic medical conditions and mental health status: disability and psychosocial resources mediate condition-specific mental health problems? Psychol Med 1997;27:1065-1077.

237. Kriegsman DMW, Penninx BWJH, Eijk JThM van, Boeke AJP, Deeg DJH. Self-reports and general practitioner information on the presence of chronic diseases in community-dwelling elderly. A study on the accuracy of patients' self-reports and on determinants of inaccuracy. J Clin Epidemiol 1996;49:1407-1417.

238. Penninx BWJH, Beekman ATF, Ormel J, Kriegsman DMW, Boeke AJP, Eijk JThM van, Deeg DJH. Psychological status among elderly people with chronic diseases: does type of disease play a part? J Psychosom Res 1996;40:521-534.

PAPERS IN REVISION

239. Vink JM, Middeldorp CM, Smit JH, Zitman FG, Snieder H, Vogelzangs N, Sullivan P, Hottenga JJ, Willemsen G, Boomsma DI, Penninx B, de Geus E. A pathway analysis of genome-wide association results reveals the importance of inflammation in Major Depressive Disorder. Biol Psychiatry; 2010; in revision.

240. Schumann G, Coin L, Lourdusamy A, Charoen P, Berger K, Bilbao A, Stacey D, Aliev F, Khan AA, Amin N, Aulchenko YS, Balkau B, Beulens JWJ, Boks MP, Bots ML, Breetvelt EJ, Cauchi S, Cavalctanti-Proença C, Chambers J, Clarke T, de Geus EJ, Delphine B, Desrivieres S, Dick D, Ducci F, Edenberg H, Esko T, Fernández-Medarde A, Fourud T, Freimer N, Gieger C, Girault JA, Grobbee DE, Guarrera S, Hartikainen AL, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni , Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lindqvist I, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy M, Numans ME, Núñez A,

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Nyholt D, Onland-Moret CN, Oostra BA, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Thorgeirsson TE, Töjnes A, Uiterwaal CS, Uitterlinden AG, Van der Harst P, Van der Schouw YT, Vogelzangs

N, Vollenwieder P, Waeber G, Wareham NJ, Waterworth DM, Whitfield J, Wichmann HE, Willemsen G, Witteman JCM, Yuan X, Zhai G, Zhao JH, Zhang W, Boomsma D, Doering A, Froguel P, Loos R, Martin N, Metspalu A, Mooser V, Peltonen L, Scott J, Spector TD, Van Duijn C, Vineis P, Kooner J, Heberlein U, Spanagel R, Jarvelin MJ, Elliott P. Identification and functional characterisation of genes associated with alcohol consumption and alcohol dependence. Nat Genetics 2010; in revision.

241. De Wit L, van Straaten A, Cuijpers P, Penninx BW. Sedentary behaviors and anxiety and depressive disorders. Psychiatr Res 2010; in revision.

242. Elzinga BM, Molendijk ML, Oude Voshaar RC, Bus BAA, Prickaerts J, Spinhoven P, Penninx BW. The impact of childhood abuse and recent stress on Brain-Derived Neurotrophic Factor and the moderating role of the BDNF gene. Psychopharmacology 2010; in revision.

243. Van der Werf E, Verboom C, Nolen WA, Penninx BW, Ormel J. Explaining heterogeneity in disability associated with current major depressive disorder: Effects of illness characteristics and comorbid mental disorders. J Affect Dis 2010; in revision.

244. van Harmelen AL, van Tol MJ, van der Wee NJA, Veltman DJ, Aleman A, Spinhoven P, Zitman FG, Penninx BW, Elzinga BM. The long-term neurobiological impact of childhood emotional abuse. Biol Psychiatry 2010; in revision.

245. van Santen A, Vreeburg SA, van der Does W, Spinhoven P, Zitman FG, Penninx BW. Psychological traits and the relationship with the Hypothalamus-Pituitary-Adrenal axis: Results from the Netherlands Study of Depression and Anxiety (NESDA). PNEC in revision.

246. Licht CM, Penninx BW, de Geus EJ. Sympathetic activity, antidepressant use and major depressive disorder. Biol Psychiatry 2010; in revision.

247. Bus BA, Molendijk ML, Penninx BW, Buitelaar JK, Prickaerts J, Elzinga BM, Oude Voshaar RC. Determinants of serum brain-derived neurotrophic factor in affective disorders. PNEC 2010; in revision.

248. De Wit L, van Straaten A, Lamers F, Cuijpers P, Penninx BW. Depressive and anxiety disorders and the association with obesity, physical and social activities. Psychiatry Res 2010; in revision.

249. Wardenaar K, Vreeburg SA, van Veen T, Giltay EJ, Veen G, Penninx BW, Zitman FG. Dimensions of depression and anxiety and the Hypothalamus-Pituitary-Adrenal axis: results from the Netherlands Study of Depression and Anxiety (NESDA). Biol Psychiatry 2010; in revision.

250.

BOOK (CHAPTERS)

1. Batelaan N, Penninx BW. De epidemiologie van angst. In: van Balkom et al. Handboek voor Angststoornissen.

2. Penninx BW, Vogelzangs N. Behavioral medicine and aging. In: Steptoe A et al. Handbook

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of Behavioral Medicine. In press 2009.

3. Snieder H, Wang X, Lagou V, Penninx BW, Riese H, Hartman CA. Role of gene-stress interactions in gene finding studies. Novartis Found Symp 2008:293;71-82.

4. Penninx BWJH. Depressione e disabilità fisica. In: Steptoe A. Depressione e malattie fisiche. ISBN 978-88-7141-772-1. CIC Edizioni internazionali, Rome 2007; pp 125-144.

5. Penninx BWJH. Aging and psychological stress. In: Fink G. Encyclopedia of Stress, 2nd edition. ISBN: 978-0-12-088503-9. Academic Press, Oxford 2007: pp 104-111.

6. Penninx BWJH. Anemia and physical health decline in old age. In: Balducci L, Ershler WB, Bennett JM. Anemia in the Elderly. Springer, New York 2007: pp 129-140.

7. Penninx BWJH. Depression and physical disability. In: Steptoe A. Depression and Physical Illness. ISBN 13-978-0-521-60360-7, Cambridge University Press, Cambridge 2006; pp 125-144.

8. Penninx BWJH. Women’s aging and depression. In: Keyes CLM and Goodman SH. Women and Depression. A handbook for the social, behavioral, and biomedical sciences. ISBN-13:978-0-521-83157-4, Cambridge University Press, Cambridge 2006: pp129-144.

9. Penninx BWJH. Emotionele problemen bij ouderen: veel voorkomend en riskant. In: Ouder worden, een kwetsbaar succes. ISBN 90-5170-6774. DTP: Textcetera, Amsterdam 2003: pp 53-60.

10. Penninx BWJH, Cavazzini C. I “coli” dell’anima. In: Ferrucci L. InChianti: Invecchiare nel Chianti. 2002, pp 167-180.

11. Penninx BWJH, Deeg DJH. Aging and psychological stress. In: Fink G. Encyclopedia of Stress. San Diego: Academic Press 2000: pp 104-111.

12. Beekman ATF, de Beurs E, Penninx BWJH, Geerlings SW. Kansen voor preventie: tien jaar onderzoek naar angst en depressie bij ouderen. In: Deeg DJH, Bosscher RJ, Broese van Groenou MI, Horn LM, Jonker C. Ouder worden in Nederlands. Tien jaar Longitudinal Aging Study Amsterdam (LASA). ISBN 90-5170-534-4. Thela Thesis, Amsterdam 2000: pp 59-67.

13. Penninx BWJH. Depressie, hartziekte en sterfte bij ouderen. [Depression, heart disease and mortality in old age]. In: Beekman ATF. Co-morbiditeit als paradigma. Symposiumverslag 1999. LeoCahn Stichting, Hontele-van Deursen, Roosendaal, 2000, pp 37-43.

14. Penninx BWJH. Emotionele vitaliteit bij ouderen. [Emotional vitality among older persons]. In: Broese van Groenou MI, Deeg DJH, Knipscheer CPM, Ligthart GJ. VU-Visies op Veroudering. ISBN 90-5170-464. Thela Thesis, Amsterdam 1998: pp 193-196.

15. Knipscheer CPM, Kriegsman DMW, Penninx BWJH, Broese van Groenou M. Ziekte en informatle hulpverlening aan ouderen [in Dutch]. In: Westendorp M, Deeg DJH, Spanjer M (eds). Ouderen in Nederland: van onderzoek naar beleid. ISBN 90-5383-545-8. VU University Press, Amsterdam 1997: pp 15-22.

16. Penninx BWJH. Social support in elderly people with chronic diseases. Does it really help? [thesis]. ISBN 90-5669-015-9. Ponsen & Looyen, Wageningen, 1996.

17. Penninx BWJH. Social support and social network among elderly with joint disorders. In: Deeg DJH, Westendorp-de Serière M (eds). Autonomy and well-being in the aging population. Report from the Longitudinal Aging Study Amsterdam 1992-1993. Amsterdam: VU University Press, 1994: pp. 89-95.

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INVITED LECTURES AND CONFERENCE CONTRIBUTIONS

1. Keynote lecture, Valerius Symposium ‘Psyche and Soma’. Amsterdam, June 5, 2010. Lecture title: Depression and cardiovascular disease: how to explain their link?

2. NESDA day, Organiser and presenter, 31 May 2010.3. Invited lecture, American Psychiatric Association, New Orleans, May 21, 2010. Lecture title:

Depression, metabolic syndrome, obesity.4. Invited lecture, National Institute of Mental Health, Maryland MD, May 3, 2010. Lecture title:

The Netherlands Study of Depression and Anxiety. 5. Invited speaker, Boerhave course, Leiden, April 22, 2010. Lecture title: Genetics and

depression.6. Keynote lecture, Neuroscience Campus Amsterdam Annual Meeting, Amsterdam. April 1,

2010. Lecture title: Depression, endophenotypes and genes: insights from NESDA.7. Invited speaker, ALLEA meeting, Madrid, February 8, 2010. Lecture title: Dutch Young

Academy.8. Organizer and presenter, KNAW symposium Genomics of gene expression. Amsterdam,

January 8, 2010. Lecture title: Genetic research in the NESDA study. 9. Invited speaker, European College of Neuropsychopharmacology (ECNP) meeting, Istanbul,

September 2009. Lecture title: Cortisol, HPA-axis genes and depression.10. Invited speaker, World Congress of Gerontology, Paris, France, July 8 2009, Lecture title:

Anemia and its functional consequences. 11. Invited speaker, FEDERA day on aging, Leiden, June 19 2009, Lecture title: Late-life

depression.12. Invited speaker, ALLEA/ESF workshop on a European Young Academy, Vienna, June 7-9

2009. Lecture title: The Dutch Young Academy.13. NESDA day, Organiser and presenter, 2 June 2009.14. Invited lecture, Jelgersma lecture, Leiden University Medical Center, 12 Mei 2009, Lecture

title: Cardiovascular risk among persons with depressive and anxiety disorders: really increased?

15. Symposium presentation, Penninx B, ‘Genoom-brede’ genetische analyse naar depressie. Voorjaarscongres psychiatrie, Groningen, 3 April 2009.

16. Oral presentation, Penninx B, Licht C, de Geus E. Depression is associated with lower blood pressure, but antidepressant use with higher blood pressure. Annual meeting of the American Psychosomatic Medicine Association, Chicago, March 10 2009.

17. Invited speaker, Tilburg University, Tilburg February 5 2009, Lecture title: ‘CVD risk in depressed patients: results from NESDA’.

18. Invited speaker, Expert meeting organized by the Netherlands Heart Association, Bilthoven, October 31 2008, Lecture title: “Depression and the stress system”.

19. Invited speaker, Psychiatry in Nijmegen symposium, Nijmegen, March 25 2008, Lecture title: “The epidemiology of depression and cardiovascular disease”.

20. Symposium presentation, Sullivan PF, Penninx B, Zitman F, Nolen W, Hoogendijk W, Smit J, Heutink P, Willemsen G, de Geus E, Boomsma D. The genetic basis of depression: the GAIN-MDD genome wide analysis among 3760 persons. Annual Meeting of the American Psychosomatic Medicine Association, Baltimore MD, March 15 2008.

21. Symposium presentation, De Geus EJ, Licht C, van Dyck R, Heutink P, Sullivan P, Willemsen G, Boomsma D, Penninx B. The genetic basis of autonomic nervous system dysfunction: a genome wide analysis. Annual Meeting of the American Psychosomatic Medicine Association, Baltimore MD, March 15 2008.

22. Symposium presentation, Verhoeff B, Hoogendijk W, Heutink P, Sullivan P, Zitman F, van Pelt

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H, de Rijk R, van Dyck R, Penninx B. The genetic basis of HPA-axis dysfunction: a genome wide analysis. Annual Meeting of the American Psychosomatic Medicine Association, Baltimore MD, March 15 2008.

23. Symposium presentation, Willemsen G, de Geus E, Heutink P, Sullivan P, Smit J, Boomsma D, Penninx B. The genetic basis of insulin and glucose: a genome-wide analysis. Annual Meeting of the American Psychosomatic Medicine Association, Baltimore MD, March 15 2008.

24. Symposium presentation, Lagou V, Hartman CA, Penninx BW, de Geus EJ, Snieder H. A genome-wide analysis scan of systolic and diastolic blood pressure. Annual Meeting of the American Psychosomatic Medicine Association, Baltimore MD, March 15 2008.

25. Invited speaker, Symposium in honor of Laureat Holsboer, Leiden, February 2008, Lecture title: “Are HPA-axis and autonomic nervous system dysregulated among regular depressed subjects: results from the Netherlands Study of Depression and Anxiety.”

26. Invited speaker, Radboud University Medical Center, Nijmegen, January 2008, Lecture title: Psychiatric Epidemiology: oridinary or special?”

27. Organizer, Symposium NESDA – verwetenschappelijking van de psychiatrie. Amsterdam, November 5, 2007.

28. Organizer, Care Onderzoeksschool dag – Prevention, 9 Juni, 2007.29. Invited speaker, National Anemia Action Council Meeting, Dallas, TX USA, November 15,

2006. Lecture title: “Anemia and Function”. 30. Invited speaker, Universiteit van Maastricht, November 7, 2006. Lecture title: “Netherlands

Study of Depression and Anxiety (NESDA): Achtergrond, opzet en methoden.31. Invited speaker, Universitair Medisch Centrum Groningen (UMCG), November 6, 2006.

Lecture title: “Netherlands Study of Depression and Anxiety (NESDA): Achtergrond, methoden en eerste resultaten.

32. Invited speaker, EURODEP collaborative action meeting, Amsterdam, 3 November 2006.33. Invited speaker, Charité, Department of Psychiatry, Berlin, Germany. October 18, 2006.

Lecture title: “Netherlands Study of Depression and Anxiety (NESDA): Rational, methods and first preliminary (psychosomatic) results”.

34. Invited speaker, Werkgroep Gezondheidsmeting, Jaarbeurs Utrecht. April 20,2006. Lecture title: “De complexiteit van somatische comorbiditeit”.

35. Paper presentation, Annual Meeting of the American Psychosomatics Society, March 2006, Denver CO. Lecture title: Late-life depression is associated with hyper- and hypoactivity of the HPA-axis.

36. Invited speaker, Vakgroep psychiatrie, Erasmus Universiteit / GGZ Rijmond. February 28, 2006. Lecture title: “What to expect from the NESDA study?”

37. Symposium presentation, 59th Annual Meeting of the Gerontological Society of America, November 2005, Dallas TX. Lecture title: Emotional vitality.........

38. Symposium presentation and chair, 59th Annual Meeting of the Gerontological Society of America, November 2005, Dallas TX. Lecture title: Metabolic syndrome predicts onset of functional limitations among older persons.

39. Paper presentation, 58th Annual Meeting of the Gerontological Society of America, November 2005, Orlando FL, Lecture title: Late-life depression is associated with hyper- and hypoactivity of the HPA-axis.

40. Poster presentation, 58th Annual Meeting of the Gerontological Society of America, November 2005, Orlando FL, Lecture title: Efficacy of physical exercise and antidepressant medication for improving emotional and physical function in depressed older persons.

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41. Invited speaker, University of Florida, Gainesville FL, November 16, 2005. Lecture title: The effect of late-life depresson on somatic health: what is the role of pathophysiology?

42. Invited speaker, Max Planck International Research Network on Aging (Maxnet Aging) Conference, November 6, 2005, Marbella, Spain. Lecture title: Concepts of physical functional status, comorbidity and frailty.

43. Panellist, Anemia in Aging Workshop, Annual meeting of the American Geriatrics Society, May 14-15, 2005. Orlando, FL, USA.

44. Invited speaker, Wake Forest University School of Medicine, Winston-Salem NC, May 6, 2005. Lecture title: Physical health consequences of late-life depression.

45. Invited lecture, Julius Centre for Health Sciences and Primary Care, Utrecht Medical Center, December 16, 2004, Utrecht. Lecture title: Netherlands Study of Depression and Anxiety: Background, Objectives and Design.

46. Paper presentation, 57th Annual Meeting of the Gerontological Society of America, November 2004, Washington DC, Lecture title: Anemia and incident falls.

47. Invited speaker, Mental dysfunctions in parkinson’s disease, October 24-27, 2004, Salzburg, Austria. Lecture title: Depression results in impaired physical function in old age.

48. Invited speaker, Annual Meeting of the Netherlands School of Primary Care Research, Utrecht, The Netherlands, May 18, 2004. Lecture title: Beloop van depressie op oude leeftijd.

49. Invited speaker, American Society of Hematology, San Diego CA, USA, December 9-11 2003. Lecture title: Late-life anemia identifies persons at risk for mortality and hospitalization.

50. Invited speaker, Annual Meeting of the American Geriatrics Society, Philadelphia MD, USA, May 10, 2003. Lecture title: Physical consequences of late-life anemia.

51. Grand round, Department of Psychiatry, Wake Forest University School of Medicine. March 21, 2003. Lecture title: The effect of depression on physical health.

52. Paper presentation, Annual Meeting of American Society of Hematology, December 2003, San Diego CA, Lecture title: Anemia in old age predicts mortality and hospitalization.

53. Paper presentation, 56th Annual Meeting of the Gerontological Society of America, November 2003, San Diego CA, Lecture title: Inflammation and incident mobility limitations: results from the Health ABC study.

54. Paper presentation, 55th Annual Meeting of the Gerontological Society of America, November 2002, Boston MA, Lecture title: Inflammation and depressive symptoms: results from the Health ABC study.

55. Symposium presentation, 55th Annual Meeting of the Gerontological Society of America, November 2002, Boston MA, Lecture title: Inflammation and the incidence of mobility limitation in old age.

56. Symposium presentation, symposium by the GSA Interest Group ‘Epidemiology of Aging’, 55 th Annual Meeting of the Gerontological Society of America, November 2002, Boston MA, Lecture title: Is sub-threshold depression a preclinical condition?

57. Grand round, Department of Public Health Sciences, Wake Forest University School of Medicine, November 7, 2002. Lecture title: Benefits of exercise in the elderly: current evidence and future plans.

58. Invited lecture, Vrije Universiteit Amsterdam, The Netherlands. April 10, 2002. Lecture title: Emotionele problemen bij ouderen: veel voorkomend en riskant. [Emotional problems in the elderly: common and a risk factor]

59. Symposium presentation, American Geriatrics Society Annual Meeting, May 15-18, 2003, Baltimore MD. Lecture title: The physical consequences of anemia in old age.

60. Paper presentation, American Geriatrics Society Annual Meeting, May 8-12, 2002, Washington DC. Lecture title: Anemia is independent risk factor for physical performance decline in old age.

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61. Lunch symposium presentation. American Medical Women’s Association. 86 th Annual Meeting, February 2002, San Antonio, TX. Lecture title: Anemia in the elderly.

62. Invitational Conference. Course of chronic disease, depressive symptoms and daily functioning. University of Maastricht, Maastricht, The Netherlands, December 21, 2001. Lecture title: The role of depression on cardiovascular mortality.

63. Paper presentation, 54th Annual Meeting of the Gerontological Society of America, November 2001, Chicago IL, Lecture title: Exercise and depressive symptoms, results from a RCT.

64. Grand round, General Clinical Research Center, Wake Forest University, October 26, 2001. Lecture title: Physical consequences of late-life depression.

65. Poster presentation, 3rd Scientific forum on quality of care and outcomes research in cardiovascular disease and stroke. September 30-October 1, 2001, Washington DC. Lecture title: Inflammation, cardiovascular disease and disability in older persons.

66. Grand round, Women's Health Center of Excellence Symposium, Wake Forest University, May 15, 2001. Lecture title: Late-life depression: Why are women more affected?

67. Invited symposium presentation, American Geriatrics Society Annual Meeting, May 9-13, 2001, Chicago IL. Lecture title: Exercise reduces the onset of ADL disability.

68. BestHealth 55 talk. April 4, 2001, June 13, 2001, April 22, 2002. Hanes Mall, Winston Salem NC. Lecture title: Late-life depression. How to improve your mood?

69. Talk at Friends Home West. March 15, 2001. Greensboro. Lecture title: How to improve your mood?

70. Visiting professor, Department of Psychiatry, Duke University, Durham NC, January 18, 2001. Lecture title: Prevalence, predictors and consequences of late-life depression.

71. Symposium presentation, 53rd Annual Meeting of the Gerontological Society of America, November 2000, Washington DC, Lecture title: Emotional vitality protects against adverse health outcomes in disabled older women

72. Poster presentation, 53rd Annual Meeting of the Gerontological Society of America, November 2000, Washington DC. Poster title: Lower extremity performance in non-disabled older persons as a predictor of hospitalization.

73. Invited lecture, Advisory board meeting Longitudinal Aging Study Amsterdam, Schoorl, The Netherlands, March 2000, Lecture title: Depression and cardiovascular mortality in older men and women.

74. Visiting professor, Sticht Center on Aging, Wake Forest University, Winston-Salem NC, December 1999. Lecture title: Physical consequences of late-life depression.

75. Symposium presentation, 52nd Annual Meeting of the Gerontological Society of America, November 1999, San Francisco CA. Lecture title: Change in depressed mood among older persons with various chronic diseases.

76. Paper presentation, 52nd Annual Meeting of the Gerontological Society of America, November 1999, San Francisco CA. Lecture title: The role of heart disease in the link between depression and death in old age.

77. Invited lecture, Leo Cahn Stichting, Ede, The Netherlands, October 1999, Lecture title: Depression, mortality and cardiac disease.

78. Symposium presentation, IVth European Congress of Gerontology, July 1999, Berlin, Germany. Lecture title: Changes in depressive symptoms among chronically ill older persons.

79. Paper presentation, IVth European Congress of Gerontology, July 1999, Berlin, Germany. Lecture title: Is depression a risk factor for dying only among older persons with cardiac disease?

80. Visiting professor, department of preventive medicine, University of Tennessee, Memphis TN, May 1999. Lecture title: The effect of depression on cardiovascular events in old age.

81. Visiting professor, Institute for interdisciplinary gerontology, University of Jyvaskyla, Jyvaskyla,

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Finland, April 1999. Lecture title: Depression and its health consequences in older persons.82. Symposium presentation, Meeting of the Dutch Association of Psychiatry, April 1999,

Noordwijkerhout, The Netherlands. Cardiac disease, depression and mortality in old age.83. Chair, Symposium, 51st Annual Meeting of the Gerontological Society of America, November

1998, Philadelphia, MD, USA Symposium title: ‘Interrelationship between depression and physical health’

84. Symposium presentation, 51st Annual Meeting of the Gerontological Society of America, November 1998, Philadelphia, MD, USA. Depressed mood and mortality in older persons.

85. Invited paper symposium presentation, 51st Annual Meeting of the Gerontological Society of America, November 1998, Philadelphia MD. Lecture title: Change in physical performance and disability in older men and women in the Netherlands.

86. Invited lecture, Meeting of the Center on Aging, Vrije University, Amsterdam, October 1998. Lecture title: Emotional vitality in older persons.

87. Invited lecture, Annual Meeting of the Netherlands School of Primary Care Research, June 1998, Amsterdam. Lecture title: The influence of social network and support characteristics on the survival of older persons.

88. Discussant, Second Dutch Conference on Psychology & Health, May 1998, Rolduc, The Netherlands. Conference topic: Changes in functioning with aging: Results from the Longitudinal Aging Study Amsterdam.

89. Paper presentation, World Congress of Gerontology, August 1997, Honolulu, USA. Lecture title: Aging women and disability: The Women’s Health and Aging Study.

90. Paper presentation, World Congress of Gerontology, August 1997, Adelaide, Australia. Lecture title: Effects of social support and personal coping resources on mortality in older age.

91. Invited lecture, Epidemiology, Demography and Biometry program, National Institute on Aging, May 1997, Bethesda MD. Lecture title: Chronic depressed mood and the incidence of cancer in old age.

92. Invited lecture, Epidemiology, Demography and Biometry program, National Institute on Aging, December 1996, Bethesda MD. Lecture title: Effects of social support and coping resources in old age: does it really help?

93. Paper presentation, 49th Annual Meeting of the Gerontological Society of America, November 1996, Washington DC. Lecture title: Effects of coping resources on depression: Different across five distinct diseases?

94. Invited lecture, Annual meeting of the Netherlands School for Primary Care Research, June 1996, Maastricht, Netherlands. Lecture title: Effects of social support and personal coping resources on depression.

95. Symposium presentation, Meeting of the Dutch Association of Psychiatry, March 1996, Amsterdam, The Netherlands. Lecture title: Depressive symptomatology and chronic disease in the elderly.

96. Paper presentation, First Dutch Conference on Psychology and Health, November 1995, Kerkrade, The Netherlands. Lecture title: Social support in patients with different chronic diseases.

97. Symposium presentation, Third European Congress of Gerontology, August 1995, Amsterdam, The Netherlands. Lecture title: Social support in chronically ill patients.

98. Paper presentation, Dutch College of General Practitioners, June 1995, Maastricht, The Netherlands. Lecture title: Social support among patients with various chronic diseases.

99. Invited lecture, Annual Meeting of the Dutch College of General Practitioners, June 1995, Maastricht, The Netherlands. Lecture title: Social support among patients with various chronic diseases

100. Poster presentation, Third International Congress of Behavioral Medicine, July 1994,

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Amsterdam, The Netherlands. Poster title: Social support and course of chronic disease in the elderly: a criteria based literature study.

101. Paper presentation, Annual Meeting of the section Gerontology and Geriatry of the Dutch Organization for Scientific Research, June 1994, Bilthoven, The Netherlands. Lecture title: Social support and social network among elderly with joint disorders.

102. Poster presentation, Symposium ‘Aging 93' of the Netherlands Institute of Care and Well being, November 1993, Rotterdam, The Netherlands. Poster title: Social support and the course of chronic diseases in the elderly: a criteria based literature study.