CURRICULUM VITAE Mark Alan Riddle, M.D.

Current Appointments

2002 - Professor Departments of Psychiatry and Pediatrics

Johns Hopkins University School of Medicine

1994 - Attending Physician The Johns Hopkins Hospital Baltimore, Maryland

Personal Data Address: Johns Hopkins University School of Medicine 550 North Broadway, Suite 203 Baltimore, MD 21287 Phone: (410) 955-2321; Fax: (410) 955-8691 E-mail: mriddle1@jhmi.edu

Education 1970 B.A. Chemistry and Political Science Indiana University Bloomington, Indiana 1973 M.S. Pharmacology Indiana University Bloomington, Indiana 1977 M.D. Doctor of Medicine Indiana University School of Medicine Indianapolis, Indiana

Postdoctoral Training

1977-78 Intern in Pediatrics Indiana University Medical Center Indianapolis, Indiana

1978-81 Resident in Psychiatry

Yale University School of Medicine New Haven, Connecticut

1981-83 Fellow in Child & Adolescent Psychiatry Yale University School of Medicine New Haven, Connecticut

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Professional Appointments

1983-89 Assistant Professor of Pediatrics & Psychiatry Yale University School of Medicine New Haven, Connecticut

1985-91 Associate Medical Director

Children’s Psychiatric Inpatient Service Yale-New Haven Hospital New Haven, Connecticut

1988-89 Acting Associate Program Director

Children’s Clinical Research Center Yale-New Haven Medical Center New Haven, Connecticut

1987-93 Medical Director

Tourette and Obsessive Compulsive Disorders Clinic Yale University School of Medicine New Haven, Connecticut

1989-93 Associate Professor of Child & Adolescent Psychiatry

Yale University School of Medicine New Haven, Connecticut

1993-02 Associate Professor

Departments of Psychiatry and Pediatrics The Johns Hopkins University School of Medicine Baltimore, MD

1993-09 Director Division of Child and Adolescent Psychiatry The Johns Hopkins University School of Medicine

2009-14 Director Children’s Interventions Research Program in Psychiatry

Division of Child and Adolescent Psychiatry The Johns Hopkins University School of Medicine

Editorial Activities 1992-97 Editorial Board Member

Journal of the American Academy of Child and Adolescent Psychiatry 1992-03 Senior Associate Editor Journal of Child and Adolescent Psychopharmacology 1998-05 Editorial Board Member Biological Psychiatry

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2003-14 Editorial Board Member Journal of Child & Adolescent Psychopharmacology

Advisory Committees and Work Groups

1988-98 Member Medical Advisory Board Tourette Syndrome Association

1993-96 Member

Work Group on Research American Academy of Child and Adolescent Psychiatry

1993-03 Examiner Committee on Certification in Child and Adolescent Psychiatry American Board of Psychiatry and Neurology

1994-99 Member

Medical Advisory Board Tourette Syndrome Association of Greater Washington

1995-00 Member

Expert Advisory Panel in Pediatrics United States Pharmacopeia

1997-98 Executive Committee Member & Pharmacology Subcommittee Chair

Maryland Task Force to Study Methylphenidate Uses on School Children

1997-01 Member Research Training Committee

American Psychiatric Association 1998-99 Member

DSM-IV Text Revision Workgroup American Psychiatric Association

2000-03 Member of Council American Academy of Child & Adolescent Psychiatry 2000-03 Chair Maryland Youth Practice Improvement Committee Maryland Mental Hygiene Administration 2001-02 Member, Children’s Workgroup National Human Research Protection Advisory Committee U.S. Department of Health and Human Services 2001-03 Member, Advisory Council Attention Deficit Hyperactivity Disorder Advisory Committee State of Maryland

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2003-07 Co-Chair Maryland Youth Practice Improvement Committee

Maryland Mental Hygiene Administration

2006-08 Advisory Committee Integrated Training Programs

American Academy of Child and Adolescent Psychiatry 2006-08 Member

Clinical Trials Consortium Tourette Syndrome Association

2007-11 Co-Chair Maryland Institute for Children’s Mental Health Maryland Mental Hygiene Administration 2008-11 Member, Children’s Mental Health Task Force Maryland Mental Hygiene Administration 2010-12 Member

Committee on Pediatric Studies Conducted Under the Best Pharmaceuticals for Children Act and the Pediatric Research Equity Act

Institute of Medicine 2012-13 Member, Psychiatry Core Group Initiative to Advance Pediatric Therapeutics National Institute of Child Health and Human Development 2006- Member

DSMB for Best Pharmaceuticals for Children Act (BPCA) National Institute of Child Health and Human Development 2011- Member

Maryland Advisory Committee for Children’s Mental Health Maryland Mental Hygiene Administration 2012- Senior Clinical Consultant Maryland Peer-to-Peer Program for Monitoring Antipsychotics in Youth Maryland State Medicaid Program 2113- Member, Steering Committee The Primary Pediatric Psychopharmacology Program The REACH Institute, New York, NY

NIH Review Groups

1992 Member, Special Review Committee Multimodal Treatment Study of ADHD (MTA) National Institute of Mental Health

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1995 Member, Review Committee (Board of Scientific Counselors)

Child Psychiatry Branch (Intramural) National Institute of Mental Health

1998 Member, Review Committee Intramural Research Program Protocols National Institute of Mental Health

1999 Member, Consensus Development Panel

Rehabilitation of Persons with Traumatic Brain Injury National Institutes of Child Health and Human Development

2000-05 Member

Interventions Scientific Review Group (SRG) National Institute of Mental Health 2005-06 Chair

Special Emphasis Panels (Child Interventions) National Institute of Mental Health

2006-07 Chair

Interventions Committee for Disorders Involving Children and Families National Institute of Mental Health

2009 Chair

Novel Interventions RFA Special Review Panel National Institute of Mental Health 2008-14 Member

Special Emphasis Panels National Institute of Mental Health

School of Medicine Committees

2008-09 Member Committee to Revise the Policy on Professional Commitments

2007-11 Member

Committee on Outside Interests

Awards, Honors

1983-85 Individual National Research Service Award National Institute of Mental Health

1996-01 Principal Investigator, Research Unit of Pediatric Psychopharmacology

National Institute of Mental Health

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1999-09 Principal Investigator, Institutional Research Training Grant (T32) National Institute of Mental Health

2004 Outstanding Service Award Maryland Interdisciplinary Council of Child and Adolescent Psychiatry

2012 Family Partnership Award Maryland Coalition of Families for Children’s Mental Health

2013 Elaine Schlosser Lewis Award for Research on Attention-Deficit Disorder American Academy of Child and Adolescent Psychiatry 2016 Silver Medal in Psychology/Mental Health The Independent Publisher Book Awards (IPPY) For Pediatric Psychopharmacology for Primary Care

Licensure and Board Certification

Current Maryland Physician License (#D0045696) 1982 Diplomat in Psychiatry American Board of Psychiatry and Neurology 1986 Diplomat in Child and Adolescent Psychiatry American Board of Psychiatry and Neurology

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Publications I. Peer-Reviewed Scientific Articles: Original Research 1. Giller E, Bialos D, Riddle MA, Sholomskas A, Harkness L: Monoamine oxidase inhibitor responsive depression. Psychiatry Research, 6:41-48, 1982. 2. Giller E, Bialos D, Harkness L, Riddle MA: Assessing treatment response to the monamine oxidase inhibitor isocarboxazid. Journal of Clinical Psychiatry, 45:44-48, 1984. 3. Riddle MA, Anderson GM, McIntosh S, Harcherik DF, Shaywitz BA, Cohen DJ: Cerebrospinal fluid monamine precursor and metabolite levels in children treated for leukemia: Age and sex effects and individual variability. Biological Psychiatry, 21:69-83, 1986. 4. Riddle MA, Shaywitz BA, Leckman JF, Anderson GM, Shaywitz SE, Hardin M, Ort S, Cohen DJ: Brief debrisoquin administration to assess central dopaminergic function in children. Life Sciences, 38:1041-1048, 1986. 5. Leckman JF, Ort S, Caruso KA, Anderson GM, Riddle MA, Cohen DJ: Rebound phenomena in Tourette’s Syndrome after abrupt withdrawal of clonidine: Behavioral, cardiovascular, and neurochemical effects. Archives of General Psychiatry, 43:1168-1176, 1986. 6. Riddle MA, Leckman JF, Cohen DJ, Anderson GM, Ort SI, Caruso KA, Shaywitz BA: Assessment of central dopaminergic function using plasma-free homovanillic acid after debrisoquin administration. Journal of Neural Transmission, 67:31-43, 1986. 7. Riddle MA, Leckman JF, Anderson GM, Ort SI, Hardin MT, Stevenson J, Cohen DJ: Plasma-free homovanillic acid: Within-and across-day stability in children and adults with Tourette’s Syndrome. Life Sciences, 40:2145-2151, 1987. 8. Riddle MA, Leckman JF, Anderson GM, Hardin MT, Ort SI, Towbin KE, Shaywitz BA, Cohen DJ: Assessment of dopaminergic function in children and adults: Long and brief debrisoquin administration combined with plasma homovanillic acid. Psychopharmacology Bulletin, 23:411-414. 1987. 9. Giller E, Bialos D, Riddle MA, Waldo CM: MAO inhibitor response: Multiaxial assessment. Journal of Affective Disorders, 14:171-175, 1988. 10. Riddle MA, Leckman JF, Anderson GM, Hardin MT, Ort SI, Stevenson J, Cohen DJ: Tourette’s syndrome and associated disorders: Clinical and neurochemical correlates. Journal of the American Academy of Child and Adolescent Psychiatry, 27:409-412, 1988. 11. Riddle MA, Leckman JF, Anderson GM, Ort SI, Hardin MT, Stevenson J, Cohen DJ: Plasma MHPG: Within-and across-day stability in children and adults with Tourette’s syndrome. Biological Psychiatry, 24:391-398, 1988. 12. Anderson GM, Riddle MA, Hoder EL, Feibel FC, Shaywitz BA, Cohen DJ: The ontogeny of 3,4-dehydroxyphenylacetic acid (DOPAC) in human cerebrospinal fluid. Journal of Neurology, Neurosurgery and Psychiatry, 51:1100-1102, 1988.

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13. Leckman JF, Riddle MA, Berrettini WH, Anderson GH, Hardin MT, Chappell P, Bissette G, Nemeroff CB, Goodman WK, Cohen DJ: Elevated CSF dynorphin A [1-8] in Tourette’s Syndrome, Life Sciences, 43:2015-2023, 1988. 14. Riddle MA, Hardin MT, Cho SC, Woolston JL, Leckman JF: Desipramine treatment of boys with attention deficit disorder and tics: Preliminary clinical experience. Journal of the American Academy of Child and Adolescent Psychiatry, 27:811-814, 1988. 15. Riddle MA, Jatlow PT, Anderson GA, Cho SC, Hardin MT, Cohen DJ, Leckman JF: Plasma debrisoquin levels in the assessment of homovanillic acid. Neuropsychopharmacology, 2:123-129, 1989. 16. Leckman JF, Riddle MA, Hardin MT, Ort SI, Swartz KL, Stevenson J, Cohen DJ: The Yale Global Tic Severity Scale (YGTSS): Initial testing of a clinician-rated scale of tic severity. Journal of the American Academy of Child and Adolescent Psychiatry, 28:566-573, 1989. 17. Woolston JL, Rosenthal SL, Riddle MA, Sparrow SS, Cicchetti D, Zimmerman LD: Childhood comorbidity of anxiety/affective disorders and behavior disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 28:707-713, 1989. 18. Anderson GM, Mefford JM, Tolliver TA, Riddle MA, Leckman JF, Cohen DJ, Murphy DL: Serotonin in human cerebrospinal fluid: A reassessment. Life Sciences, 46:247-255, 1990. 19. Dykens E, Leckman JF, Riddle MA, Hardin MT, Schwartz S, Cohen DJ: Intellectual, academic, and adaptive functioning of Tourette syndrome children with and without attention deficit disorder. Journal of Abnormal Child Psychology, 18:607-715, 1990. 20. Riddle MA, Scahill L, King R, Hardin MT, Towbin KE, Leckman JF, Cohen DJ: Obsessive compulsive disorder in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 29:766-772, 1990. 21. Riddle MA, Hardin MT, King RA, Scahill L, Woolston JL: Fluoxetine treatment of children and adolescents with Tourette’s and obsessive compulsive disorders: Preliminary clinical experience. Journal of the American Academy of Child and Adolescent Psychiatry, 29:45-48, 1990. 22. Woolston JL, Riddle MA: The role of advanced technology in inpatient child psychiatry: leading edge or useful aid? Journal of the American Academy of Child and Adolescent Psychiatry, 29:905-908, 1990. 23. Leckman JF, Hardin MT, Riddle MA, Stevenson J, Ort SI, Cohen DJ: Clonidine treatment of Gilles de la Tourette syndrome. Archives of General Psychiatry, 48:324-328, 1991. 24. Riddle MA, King RA, Hardin MT, Scahill L, Ort S, Leckman JF: Behavioral side effects of fluoxetine in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 1:193-198, 1991. 25. King RA, Riddle MA, Chappell PB, Hardin MT, Anderson GM Lombroso P, Scahill L: Emergence of self-destructive phenomena in children and adolescents during fluoxetine treatment. Journal of the American Academy of Child and Adolescent Psychiatry, 30:179-186, 1991.

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26. Chappell PB, Leckman JF, Riddle MA, Anderson GM, Listwack SJ, Ort SI, Hardin MT, Scahill LD, Cohen DJ: Neuroendocrine and behavioral effects of naloxone in Tourette syndrome. Advances in Neurology, 58:253-262, 1991. 27. Riddle MA, Scahill L, King RA, Hardin MT, Anderson GM, Ort SI, Smith JC, Leckman JF, Cohen DJ: Double-blind, crossover trial of fluoxetine and placebo in children and adolescents with obsessive compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 31:1062-1069, 1992. 28. Peterson BS, Riddle MA, Cohen DJ, Katz LD, Smith JC, Leckman JF: Human basal ganglia volume asymmetries on magnetic resonance images. Magnetic Resonance Imaging, 11:493-498, 1993. 29. Peterson BS, Riddle MA, Cohen DJ, Katz LD, Smith JC, Hardin MT, Leckman JF: Reduced basal ganglia volumes in Tourette’s syndrome using three-dimensional reconstruction techniques from magnetic resonance images. Neurology, 43:941-949, 1993. 30. Chappell P, Riddle M, Anderson G, Scahill L, Hardin M, Walker D, Dohen D, Leckman J: Enhanced stress responsivity of Tourette syndrome patients undergoing lumbar puncture. Biological Psychiatry, 36:35-43, 1994. 31. Peterson BS, Leckman JF, Duncan J, Wetzles R, Riddle MA, Hardin MT, Cohen DJ: Corpus callosum morphology from magnetic resonance images in Tourette’s syndrome. Psychiatry Research: Neuroimaging, 55:85-99, 1994. 32. Apter A, Ratzoni G, King RA, Weizman A, Iancu I, Binder M, Riddle MA: Fluvoxamine open-label treatment of adolescent inpatients with obsessive-compulsive disorder or depression. Journal of the American Academy of Child and Adolescent Psychiatry, 33:342-348, 1994. 33. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McSwiggan-Hardin MT, McDougle CJ, Barr LC, Cohen DJ: Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder: Comparison with Tourette’s syndrome and healthy controls. Arch of General Psychiatry, 51:782-792, 1994. 34. Peterson BS, Gore JC, Riddle MA, Cohen DJ, Leckman JF: Abnormal Magnetic Resonance Imaging T2 relaxation time asymmetries in Tourette’s syndrome. Psychiatry Research: Neuroimaging, 55:205-221, 1994. 35. Leckman JF, Anderson GM, Riddle MA, Goodman WK, Price LH, Chappell PB, McSwiggan-Hardin MT, Walker DE, Scahill LD, Ort SI, Pauls DL, Cohen DJ: CSF biogenic amines in obsessive compulsive disorder, Tourette’s syndrome and healthy controls. Neuropsychopharmacology, 12:73-86, 1995. 36. Tierney E, Joshi PT, Llinas JF, Rosenberg LA, Riddle MA: Sertraline for depression in children and adolescents: Preliminary clinical experience. Journal of Child and Adolescent Psychopharmacology, 5:13-27, 1995. 37. Chappell PB, Riddle MA, Scahill L, Lynch KA, Schultz R, Arnsten A, Leckman JF, Cohen DJ: Guanfacine treatment of comorbid attention-deficit hyperactivity disorder and Tourette’s

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syndrome: Preliminary clinical experience. Journal of the American Academy of Child and Adolescent Psychiatry, 34:1140-1146, 1995. 38. Riddle MA, Lynch KA, Scahill L, deVries A, Cohen DJ, Leckman JF: Methylphenidate discontinuation and re-initiation during long-term treatment of children with Tourette’s disorder and attention-deficit hyperactivity disorder: A pilot study. Journal of Child and Adolescent Psychopharmacology, 5:205-214, 1995. 39. King RA, Scahill L, Vitulano LA, Schwab-Stone M, Tercyak KP, Riddle MA: Childhood trichotillomania: Clinical phenomenology, comorbidity, and family genetics. Journal of the American Academy of Child and Adolescent Psychiatry, 34:1451-1459, 1995. 40. Luthar SS, Woolston JL, Sparrow SS, Zimmerman LD, Riddle MA: Adaptive behaviors among psychiatrically hospitalized children: The role of intelligence and related attributes. Journal of Clinical Child Psychology, 24:98-108, 1995. 41. Walkup JT, LaBuda MC, Hurko O, Brown J, Riddle MA, Singer HS: Family study and segregation analysis of Tourette’s syndrome: Evidence for a mixed model of inheritance. American Journal of Human Genetics, 59:684-693, 1996. 42. Chappell P, Leckman J, Goodman W, Bissette G, Pauls D, Anderson, G, Riddle M, Scahill L, McDougle C, Cohen D: Elevated cerebrospinal fluid corticotropin-releasing factor in Tourette's syndrome: Comparison to obsessive compulsive disorder and normal controls. Biological Psychiatry, 39:776-783, 1996. 43. Scahill L, Riddle MA, McSwiggin-Hardin M, Ort SI, King RA, Goodman WK, Leckman JF: Children’s Yale-Brown Obsessive Compulsive Scale: reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36:844-852, 1997. 44. Zito J, Safer DJ, dosReis S, Magder LS, Riddle MA: Methylphenidate patterns among Medicaid youths. Psychopharmacology Bulletin, 33:143-147, 1997. 45. Scahill L, Riddle MA, King RA, Hardin MT, Rasmusson A, Makuch RW, Leckman J: Fluoxetine has no marked effect on tic symptoms in patients with Tourette syndrome: A double-blind, placebo-controlled study. Journal of Child and Adolescent Psychopharmacology, 7:75-85, 1997. 46. Zito JM, Safer D, dosReis S, Riddle MA: Racial disparity in psychotropic medication prescribed for youth. Journal of the American Academy of Child and Adolescent Psychiatry, 37(2):179-184, 1998. 47. Zito JM, Safer DJ, Riddle MA, Johnson RE, Speedie SM, Fox M: Prevalence variations in psychotropic treatment of children. Journal of Child and Adolescent Psychopharmacology, 8:99-105, 1998. 48. The Tourette Syndrome Association International Consortium for Genetics: A complete genome screen in sib pairs affected by Gilles de la Tourette Syndrome: American Journal of Human Genetics, 65:1428-1436, 1999.

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49. Grados M, Scahill L, Riddle MA: Pharmacotherapy in children and adolescents with obsessive-compulsive disorder. Child and Adolescent Psychiatric Clinics of North America 8:617-634, 1999. 50. Research Units on Pediatric Psychopharmacology (RUPP) Autism Network: Background and rationale for an initial controlled study of risperidone. Child and Adolescent Psychiatric Clinics of North America, 9:201-224, 2000. 51. Nestadt G, Samuels J, Riddle M, Bienvenu III OJ, Liang K-Y, LaBuda M, Walkup J, Grados M, Hoehn-Saric R: A family study of obsessive-compulsive disorder. Archives General Psychiatry, 57:358-363, 2000. 52. Bienvenu OJ, Samuels JF, Riddle MA, Hoehn-Saric R, Liang KY, Cullen BAM, Grados MA, Nestadt G: The relationship of obsessive-compulsive disorder to possible spectrum disorders: results from a family study. Biological Psychiatry, 48:287-293, 2000. 53. Samuels J, Nestadt G, Bienvenu OJ, Costa PT, Riddle MA, Liang KY, Hoehn-Saric R, Grados MA, Cullen BAM: Personality disorders and normal personality dimensions in obsessive-compulsive disorder: results from the Johns Hopkins OCD family study. British Journal of Psychiatry, 177:457-462, 2000. 54. Nestadt G, Lan T, Samuels J, Riddle M, Bienvenu OJ, Liang KY, Hoehn-Saric R, Cullen B, Grados M, Beaty TH, Shugart YY: Complex segregation analysis provides compelling evidence for a major gene underling obsessive-compulsive disorder and for heterogeneity by sex. American Journal of Human Genetics, 67:1611-1616, 2000. 55. Riddle MA, Reeve EA, Yaryura-Tobias JA, Wong LF, Claghorn JL, Gaffney G, Greist JH, Holland D, McConville B, Piggott T, Pravetz M, Walkup JT: Fluvoxamine for children and adolescents with obsessive compulsive disorder: A controlled multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40:222-229, 2001. 56. Ghuman JK, Ginsburg GS, Subramaniam G, Ghuman HS, Kau AS, Riddle MA: Psychostimulants in preschool children with attention-deficit/hyperactivity disorder: Clinical evidence from a developmental disorders institution. Journal of the American Academy of Child and Adolescent Psychiatry, 40:516-524, 2001. 57. Cullen B, Samuels J, Bienvenu OJ, Grados M, Hoehn-Saric R, Hahn J, Liang K-Y, Wellen D, Dees M, Riddle M, Nestadt G: The relationship of pathologic skin picking to obsessive-compulsive disorder. Journal of Nervous and Mental Disease, 189(3):193-195, 2001. 58. Nestadt G, Samuels J, Riddle MA, Liang KY, Bienvenu OJ, Hoehn-Saric R, Grados M, Cullen B: The relationship between obsessive-compulsive disorder and anxiety and affective disorders: results from the Johns Hopkins OCD family study. Psychological Medicine, 31:481-487, 2001. 59. Cullen BA, Samuels JF, Bienvenu OJ, Grados M, Hoehn-Saric R, Hahn J, Liang KY, Wellen D, Dees M, Riddle MA, Nestadt G: Pathological skin picking and obsessive-compulsive disorder. Journal of Nervous and Mental Disease, 2001; 189: 193-195. 60. The Research Units of Pediatric Psychopharmacology (RUPP) Anxiety Study Group: Walkup JT, Labellarte MJ, Riddle MA, Pine DS, Greenhill L, Klein R, Davies M, Sweeney M,

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Abikoff H, Hack S, Klee B, McCracken J, Bergman L, Piacentini J, March J, Compton S, Robinson J, O’Hara T, Baker S, Vitiello B, Ritz L, Roper M: Fluvoxamine for the treatment of anxiety disorders in children and adolescents. New England Journal of Medicine, 344:1279-1285, 2001. 61. Grados MA, Riddle MA, Samuels JF, Liang KY, Hoehn-Saric R, Bienvenu OJ, Walkup JT, Song DH, Nestadt G: The familial phenotype of obsessive-compulsive disorder in relation to tic disorders: The Hopkins OCD family study. Biological Psychiatry, 50:559-565, 2001. 62. Walkup J, Labellarte M, Riddle MA, Pine DS, Greenhill L, Fairbanks J, Klein R, Davies M, Sweeney M, Abikoff H, Hack S, Klee B, Bergman RL, Lynn D, McCracken J, March J, Gammon P, Vitiello B, Ritz L, Roper, M: Treatment of pediatric anxiety disorders: An open-label extension of the research units on pediatric psychopharmacology anxiety study. Journal of Child and Adolescent Psychopharmacology, 12:175-188, 2001.

63. Greenhill LL, Vitiello B, Abikoff H, Levine J, March JS, Riddle MA, Capasso L, Cooper T, Davies M, Fisher P, Findling RL, Fried J, Labellarte M, McCracken J, McMahon DJ, Robinson J, Skrobala AM, Schahill L, Walkup J, Zito, J: Improving the methods for evaluating the safety of psychotropic medications in children and adolescents. Current Therapeutic Research, 62:873-884, 2001. 64. Samuels J, Bienvenu OJ, Riddle MA, Cullen BAM, Grados MA, Liang K-Y, Hoehn-Saric R, Nestadt G: Hoarding in obsessive-compulsive disorder: results from a case-control study. Behaviour Research and Therapy, 40:517-528, 2002. 65. Vasa RA, Gerring J, Grados M, Slomine B, Christensen J, Rising W, Denckla M, Riddle MA: Anxiety following severe pediatric closed head injury. Journal of the American Academy of Child and Adolescent Psychiatry, 41:148-156, 2002. 66. The Tourette’s Syndrome Study Group: Kurlan R, Goetz CG, McDermott MP, Plumb S, Singer J, Budman C, Coffey B, Juncos J, Mink J, Stebbins G, Tuite P, Seeberger L, Pelham WE, Palumbo D, Giuliano J, Kieger M, Lane J, Pearson N, Sine L, Parsons K, Peters S, Thorne-Petrizzi D, Parks K, Kim G, Craddock K, Wood C, Randle J, Janko K, Lasher D, Johnston T, Bean S, Riddle M, Leckman JF, Oakes D, Richard I, Sehgal N, Hogarth P, Marcus D, Kieburtz K, Harris P, Sulkes S, Cox C, LaDonna D, Rower C, Greiner A: Treatment of ADHD in children with tics. A randomized controlled trial. Neurology 58:527-536, 2002. 67. The Research Units on Pediatric Psychopharmacology Anxiety Study Group (RUPP): Riddle MA, Ginsburg GS, Walkup JT, Labellarte MJ, Pine DS, Davies M, Greenhill L, Sweeney M, Klein R, Abikoff H, Hack S. Klee B, McCracken J, Bergman L, Piacentini J, March J, Compton S, Robinson J, O’Hara T, Baker S, Vitiello B, Ritz L, Roper M: The Pediatric Anxiety Rating Scale (PARS): Development and Psychometric Properties. Journal of the American Academy of Child and Adolescent Psychiatry, 41:1061-1069, 2002. 68. The Research Units on Pediatric Psychopharmacology Anxiety Study Group (RUPP): Walkup J, Labellarte M, Riddle MA, Pine DS, Greenhill L, Fairbanks J, Klein R, Davies M, Sweeney M, Abikoff H, Hack S, Klee B, Bergman RL, Lynn D, McCracken J, March J, Gammon P, Robinson J, O’Hara T, Baker S, Vitiello B, Ritz L, Roper M: Treatment of pediatric anxiety disorders: an open-label extension of the research Units on Pediatric Psychopharmacology Anxiety Study. Journal of Child and Adolescent Psychopharmacology, 12: 175-188, 2002.

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69. Barnett SR, dosReis S, Riddle MA & The Maryland Youth Practice Improvement Committee for Mental Health: Improving the management of acute aggression in state residential and inpatient psychiatric facilities for youths. Journal of the American Academy of Child and Adolescent Psychiatry, 41: 897-905, 2002. 70. Nestadt G, Samuels JF, Riddle MA, Bienvenu OJ, Liang KY, Grados MA, Cullen B: Obsessive-compulsive disorder: defining the phenotype. J Clin Psychiatry 63: Suppl 6 5-7, 2002. 71. The Research Units on Pediatric Psychopharmacology Anxiety Study Group (RUPP): Walkup JT, Labellarte MJ, Riddle MA, Pine DS, Greenhill L, Klein R, Davies M, Sweeney M, Abikoff H, Hack S, Klee B, McCracken J, Bergman L, Piacentini J, March J, Compton S, Robinson J, O’Hara T, Baker S, Vitiello B, Ritz L, Roper M: Searching for moderators and mediators of pharmacological treatment effects in children and adolescents with anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 42: 13-21, 2003. 72. Greenhill LL, Vitiello B, Riddle MA, Fisher P, Shockey E, March JS, Levine J, Fried J, Abikoff H, Zito JM, McCracken JT, Findling RL, Robinson J, Cooper TB, Davies M, Varipatis E, Labellarte MJ, Scahill L, Walkup JT, Capasso L, Rosengarten J: Review of safety assessment methods used in pediatric psychopharmacology. Journal of the American Academy of Child & Adolescent Psychiatry 42: 627-633, 2003. 73. Vitiello B, Riddle MA, Greenhill LL, March JS, Levine J, Schachar RJ, Abikoff H, Zito JM, McCracken JT, Walkup JT, Findling RL, Robinson J, Cooper TB, Davies M, Varipatis E, Labellarte MJ, Scahill L, Capasso L: How can we improve the assessment of safety in child and adolescent psychopharmacology? Journal of the American Academy of Child & Adolescent Psychiatry 42: 634-641, 2003. 74. Labellarte MJ, Crosson JE, Riddle MA: The relevance of prolonged QTc measurement to pediatric psychopharmacology. Journal of the American Academy of Child & Adolescent Psychiatry 42: 642-650, 2003. 75. Greenhill LL, Vitiello B, Abikoff H, Levine J, March JS, Riddle MA, Capasso L, Cooper TB, Davies M, Fisher P, Findling RL, Fried J, Labellarte MJ, McCracken JT, McMahon D, Robinson J, Skrobala A, Scahill L, Varipatis E, Walkup JT, Zito JM: Developing methodologies for monitoring long-term safety of psychotropic medications in children: report on the NIMH Conference, September 25, 2000. Journal of the American Academy of Child & Adolescent Psychiatry 42: 651-655, 2003. 76. Nestadt G, Addington A, Samuels J, Liang KY, Bienvenu OJ, Riddle M, Grados M, Hoehn-Saric R and Cullen B: The identification of OCD-related subgroups based on comorbidity. Biological Psychiatry 53: 914-920, 2003. 77. dosReis S, Barnett SR, Love RC, Riddle MA, Maryland Youth Practice Improvement Committee: Recommendations for managing acute aggressive behavior of children and adolescents in residential and inpatient treatment facilities. Psychiatric Services 54: 1357-1363, 2003.

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78. Zito JM, Safer DJ, dosReis S, Gardner JF, Magder L, Soeken K, Boles M, Lynch F and Riddle MA: Psychotropic practice patterns for youth: A ten year perspective. Archives of Pediatric Adolescent Medicine 157: 17-25, 2003. 79. Vitiello B, Riddle MA, Greenhill LL et al: How can we improve the assessment of safety in child and adolescent psychopharmacology? Journal of the American Academy of Child and Adolescent Psychiatry, 42:634-641, 2003. 80. Hong JP, Samuels J, Bienvenu OJ 3rd, Cannistraro P, Grados M, Riddle MA, Liang KY, Cullen B, Hoehn-Saric R, Nestadt G: Clinical correlates of recurrent major depression in obsessive-compulsive disorder. Depression and Anxiety 2004; 20:92-97. 81. Vasa R, Grados MA, Slomine B, Herskovits E, Thompson RE, Salorio C, Christensen J, Wursta C, Riddle MA, Gerring JP: Neuroimaging correlates of anxiety after pediatric traumatic brain injury. Biological Psychiatry 55: 208-216, 2004. 82. Vitiello B, Heiligenstein JH, Riddle MA, Greenhill LL, Fegert JM: The interface between publicly funded and industry-funded research in pediatric psychopharmacology: Opportunities for integration and collaboration. Biological Psychiatry 56: 3-9, 2004. 83. Labellarte M, Zumbrunnen T, Brennan J, Biederman J, Connor J, Emslie G. Ferguson J, Khan A, Ruckle J, Sallee R, Riddle M: Multiple-dose pharmacokinetics of fluvoxamine in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 43: 1497-1505, 2004. 84. Greenhill LL, Vitiello B, Fisher P, Levine J, Davies M, Abikoff H, Chrisman AK, Chuang S, Findling RL, March J, Scahill L, Walkup J, Riddle MA: Comparison of increasingly detailed elicitation methods for the assessment of adverse events in pediatric psychopharmacology. Journal of the American Academy of Child and Adolescent Psychiatry 43: 1488-1496, 2004. 85. Hong JP, Samuels J, Bienvenu OJ, Cannistraro P, Grados M, Riddle MA, Liang KY, Cullen B, Hoehn-Saric R, Nestadt G: Clinical correlates of recurrent major depression in obsessive-compulsive disorder. Depression and Anxiety 20: 86-91, 2004. 86. Willour VL, Yao Shugart Y, Samuels J, Grados M, Cullen B, Bienvenu OJ III, Want Y, Liang KY, Valle D, Hoehn-Saric R, Riddle M, Nestadt G: Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder. Am J Hum Genet 75: 508-513, 2004. 87. RUPP ADHD/Anxiety Study Group (RUPP): Abikoff H, McGough J, Vitiello B, McCracken J, Davies M, Walkup J, Riddle M, Oatis M, Greenhill L, Skrobala A, March J, Gammon P, Robinson J, Lazell R, McMahon D, Ritz L: Sequential pharmacotherapy for children with comorbid attention-deficit/hyperactivity and anxiety disorders, Journal of the American Academy of Child and Adolescent Psychiatry 44: 418-427, 2005. 88. Samuels J, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Pinto A, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Bienvenu OJ, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G: The OCD Collaborative Genetics Study: Methods and sample description. Neuropsychiatric Genetics. 141: 201-207, 2006.

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89. Kollins SH, Greenhill LL, Swanson J, Wigal S, Abikoff H, McCracken JT, Riddle M, McGough JJ, Vitiello B, Wigal T, Skrobala AM, Posner K, Ghuman JK, Davies M, Cunningham C, Bauzo BA: Rationale, design and methods of the preschool ADHD treatment study (PATS). Journal of American Academy of Child & Adolescent Psychiatry 45: 1275-1283, 2006. 90. Greenhill LL, Kollins S, Abikoff H, McCracken J, Riddle M, Swanson J, McGough J, Wigal S, Wigal T, Vitiello B, Skrobala A, Posner K, Ghuman J, Cunningham C, Davies M, Chuang S, Cooper T, for the PATS Study Group. Efficacy and safety of immediate-release Methylphenidate treatment for preschoolers with ADHD. Journal of the American Academy of Child & Adolescent Psychiatry 45: 1284-1293, 2006. 91. Wigal T, Greenhill LL, Chuang S, McGough J, Vitiello B, Skrobala AM, McSwanson J, Wigal S, Abikoff H, Kollins SH, McCracken JT, Riddle M, Posner K, Ghuman JK, Davies M, Thorp B, Stehli A: Safety and tolerability of Methylphenidate in preschool children with ADHD. Journal of the American Academy of Child & Adolescent Psychiatry 45: 1294-1303, 2006. 92. Swanson J, Greenhill L, Wigal T, Kollins S, Stehli-Nguyen A, Davies M. Chuang S, Vitiello B, Skrobala AM, Abikoff H. Oatis M, McCracken J, McGough J, Riddle M, Ghuman J, Cunningham C, Wigal S and the PATS group: Stimulant-related reductions of growth rates in the PATS. Journal of the American Academy of Child & Adolescent Psychiatry 45: 1304-1313, 2006. 93. McGough JJ, McCracken JT, Swanson J, Riddle M, Kollins SH, Greenhill LL, Abikoff H, Davies M, Chuang S, Wigal T, Wigal S, Posner K, Skrobala A, Kastelic E, Cunningham C, Shigawa S, Moyzis RK, Vitiello B, and the PATS study group. Pharmacogenetics of Methylphenidate response in preschoolers with ADHD. Journal of American Academy of Child & Adolescent Psychiatry 45: 1314-1322, 2006. 94. Ginsburg GS, Riddle MA, Davies M: Somatic symptoms in children and adolescents with anxiety disorders. Journal of the American Academy of Child & Adolescent Psychiatry 45: 1179-1187, 2006. 95. Shugart YY, Samuels J, Willour VL, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Want Y, Pinto A, Fyer AJ, Piacentini J, Pauls D, Cullen B, Rasmussen SA, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G: Genome-wide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 15q, and 1q. Molecular Psychiatry 11: 763-770, 2006. 96. Wellen D, Samuels J, Bienvenu OJ, Grados M, Cullen B, Riddle M, Liang KY, Nestadt G: The diagnostic utility of the Leyton-Obsessional Inventory to distinguish OCD and OCPD. Depression and Anxiety 24: 301-306, 2006. 97. Cullen B, Riddle MA, Brown C, Bienvenu OJ, Grados M, Willour VL, Hoehn-Saric R, Liang KY, Samuels J, Nestadt G: Factor analysis of the Yale-Brown Obsessive Compulsive Scale in a family study of obsessive compulsive disorder. Depression and Anxiety 24: 130-138, 2007. 98. Samuels JF, Bienvenu OJ, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Greenberg BD, Knowles JA, Piacentini J, Cannistraro PA, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G: Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behavior Research and Therapy 45: 673-686, 2007.

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99. Rynn MA, Riddle MA, Yeung PP, Kunz NR: Efficacy and safety of venlafaxine ER in the treatment of children and adolescents with generalized anxiety disorder: two placebo-controlled trials. Am J Psychiatry 164: 290-300, 2007. 100. Hasler G, Pinto A, Greenberg BD, Samuels J, Fyer AJ, Pauls D, Knowles JA, McCracken J, Piacentini J, Riddle M, Rauch SL, Rasmussen S, Willour G, Grados M, Cullen B, Bienvenu OJ, Shugart Y, Liang KY, Hoehn-Saric R, Wang Y, Nestadt G, Murphy DL: Familiality of factor analysis-derived YBOCS dimensions in OCD affected sibling pairs from the Obsessive-Compulsive Genetics Collaborative Study. Biological Psychiatry 61: 617-625, 2007. 101a. Samuels J, Shugart YY, Grados MA, Willour VL, Bienvenu OJ, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Nestadt G: Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive compulsive Disorder: Results from the OCD Collaborative Genetics Study. American Journal of Psychiatry 164: 493-499, 2007. 101b. Samuels J, Shugart YY, Grados MA, Willour VL, Bienvenu OJ, Greenberg BD, Knowles JA, McCraken JT, Rauch SL, Murphy DL, Wang Y, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Cullen B, Rasmussen SA, Hoehn-Saric R, Valle D, Liang K, Riddle MA, Nestadt G: Ligamiento significativo al acaparamiento compulsivo en el cromosoma 14 en familias con trastorno obsesivo-compulsivo: Resultados del OCD Collaborative genetics study (Spanish version). American Journal of Psychiatry (Ed Esp) 10: 370-376, 2007. 102. Posner K, Melvin GA, Murray DW, Gugga SS, Fisher P, Skrobala AM, Cunningham C, Vitiello B, Abikoff HB, Ghuman JK, Kollins SH, Wigal SB, Wigal T, McCracken JT, McGough JJ, Kastelic E, Boorady R, Davies M, Chuang SZ, Swanson JM, Riddle MA, Greenhill LL: Clinical Presentation of ADHD in Preschool Children: Preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 547-562, 2007. 103. Ghuman JK, Riddle MA, Vitiello B, Greenhill LL, Chuang SZ, Wigal SB, Kollins SH, Abikoff HB, McCracken JT, Kastelic E, Scharko AM, McGough JJ, Murray D, Evans L, Swanson JM, Wigal T, Posner K, Cunningham C, Davies M, Skrobala AM: Comorbidity moderates response to Methylphenidate in the preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 563-580, 2007. 104. Abikoff HB, Vitiello B, Riddle MA, Cunningham C, Greenhill LL, Swanson JM, Chuang SZ, Davies M, Kastelic E, Wigal SB, Evans L, Ghuman JK, Kollins SH, McCracken JT, McGough JJ, Murray D, Posner K, Skrobala AM, Wigal T. Methylphenidate effects on functional outcome in the preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 581-592, 2007. 105. Vitiello B, Abikoff HB, Chuang SZ, Kollins SH, McCracken JT, Riddle MA, Swanson JM, Wigal T, McGough JJ, Ghuman JK, Wigal SB, Skrobala AM, Davies M, Posner K, Cunningham C, Greenhill LL: Effectiveness of Methylphenidate in the 10-Month continuation phase of the preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 593-604, 2007. 106. Murray D, Kollins SH, Hardy K, Abikoff HB, Swanson JM, Cunningham C, Vitiello B, Riddle MA, Davies M, Greenhill LL, McCracken JT, McGough JJ, Posner K, Skrobala AM, Wigal T,

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Wigal SB, Ghuman JK, Chuang SZ: Parent vs. Teacher ratings of ADHD symptoms in the preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 605-620, 2007. 107. Hardy KK, Kollins SH, Murray DW, Riddle MA, Greenhill LL, Cunningham C, Abikoff HB, McCracken JT, Vitiello B, Davies M, McGough JJ, Posner K, Skrobala AM, Swanson JM, Wigal T, Wigal SB, Ghuman JK, Chuang SZ: Factor structure of parent and teacher rated ADHD symptoms in preschoolers in the Preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 621-634, 2007. 108. Swanson JM, Moyzis R, McGough JJ, McCracken JT, Riddle MA, Kollins SH, Greenhill LL, Abikoff HB, Wigal T, Wigal SB, Posner K, Skrobala AM, Ghuman JK, Cunningham C: Effects of source of DNA on genotyping success rate and Allele percentages in the Preschoolers with ADHD Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 635-646, 2007. 109. Pinto A, Greenberg BD, Grados MA, Bienvenu OJ, Samuels JF, Murphy DL, Hasler G, Stout RL, Rauch SL, Shugart YY, Pauls DL, Knowles JA, Fyer AJ, McCracken JT, Piacentini J, Wang Y, Willour VL, Cullen B, Liang KY, Hoehn-Saric R, Riddle MA, Rasmussen A, Nestadt G: Further development of YBOCS dimensions in the OCD Collaborative Genetics Study: Symptoms vs categories, Psychiatry Research 160: 83-93, 2008. 110. Samuels JF, Bienvenu OJ, Grados MA, Cullen B, Riddle MA, Liang KY, Eaton WW, Nestadt G: Prevalence and correlates of hoarding behavior in a community-based sample. Behaviour Research and Therapy 46:836-844, 2008. 111. Cullen B, Samuels JF, Pinto A, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Greenberg BD, Knowles JA, Piacentini J, Bienvenu OJ, Grados MA, Riddle MA, Rasmussen SA, Pauls DL, Willour VL, Shugart YY, Liang KY, Hoehn-Saric R, Nestadt G: Demographic and clinical characteristics associated with treatment status in family members with Obsessive-Compulsive Disorder. Depression and Anxiety 25:218-224, 2008. 112. Grados MA, Vasa RA, Riddle MA, Slomine BS, Salorio C, Christensen J, Gerring J: New Onset Obsessive-Compulsive Symptoms in children and adolescents with severe traumatic brain injury. Depression and Anxiety 25: 398-407, 2008. 113. Cullen B, Samuels J, Grados M, Landa R, Bienvenu OJ, Liang KY, Riddle M, Hoehn-Saric R, Nestadt G: Social and communication difficulties and obsessive-compulsive disorder. Psychopathology 41:194-200, 2008. 114. Liang KY, Wang Y, Shugart YY, Grados MA, Fyer AJ, Rauch SL, Murphy DL, McCracken JT, Rasmussen SA, Cullen B, Hoehn-Saric R, Greenberg BD, Pinto A, Knowles JA, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Samuels JF, Nestadt G: Evidence for potential relationship between EEAC1 (SLC1A1) and a putative genetic linkage region on chromosome 14q to obsessive-compulsive disorder with compulsive hoarding. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 147B: 1000-1002, 2008. 115. Samuels JF, Bienvenu OJ, Pinto A, Murphy DL, Piacentini J, Rauch SL, Fyer AJ, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Liang KY, Hoehn-Saric R, Pulver AE, Nestadt G: Sex-specific clinical correlates of hoarding in Obsessive-Compulsive Disorder. Behaviour Research and Therapy 46: 1040-1046, 2008.

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116. Pinto A, Greenberg BD, Grados MA, Bienvenu OJ, Samuels JF, Murphy DL, Hasler G, Stout RL, Rauch SL, Shugart YY, Pauls DL, Knowles JA, Fyer AJ, McCracken JT, Piacentini J, Wang Y, Willour VL, Cullen B, Liang KY, Hoehn-Saric R, Riddle MA, Rasmussen SA, Nestadt G: Further development of YBOCS dimensions in the OCD Collaborative Genetics Study: Symptoms vs categories. Psychiatry Research 160: 83-93, 2008. 117. Samuels J, Bienvenu OJ, Pinto A, Murphy DL, Piacentini J, Rauch SL, Fyer AJ, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Cullen B, Riddle MA, Rasmussen SA, Pauls DL, Liang KY, Hoehn-Saric R, Pulver AE, Nestadt G: Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder. Behavior Research and Therapy 46: 1040-1046, 2008. 118. Wilcox HC, Grados M, Samuels J, Riddle MA, Bienvenu III OJ, Pinto A, Cullen B, Wang Y, Shugart YY, Liang KY, Nestadt G: The Association of Parental Bonding with Obsessive Compulsive Disorder in Offspring at High Familial Risk. Journal of Affective Disorders, 111: 31-39, 2008. 119. Wissow L, Anthony B, Brown J, dosReis S, Gadomski A, Ginsburg G, Riddle M: A common factors approach to improving the mental health capacity of pediatric primary care. Adm Policy Ment Health 35: 305-318, 2008. 120. Reinblatt SP, dosReis S, Walkup JT, Riddle MA: Activation adverse events induced by the selective serotonin reuptake inhibitor fluvoxamine in children and adolescents. Journal of Child and Adolescent Psychopharmacology 19: 119-126, 2009. 121. Brent D, Greenhill L, Compton S, Emslie G, Wells K, Walkup J, Vitiello B, Bukstein O, Stanley B, Posner K, Kennard B, Cwik M, Wagner A, Coffey B, March J, Riddle M, Goldstein T, Curry J, Barnett S, Capasso L, Zelazny J, Shen S, Guggia S, Turner B: The Treatment of Adolescent Suicide Attempters (TASA): Predictors of Suicidal Events in an Open Treatment Trial. Journal of the American Academy of Child and Adolescent Psychiatry, 48: 987-996, 2009. 122. Vitiello B, Brent D, Greenhill L, Emslie G, Wells K, Walkup J, Stanley B, Bukstein O, Kennard BD, Compton S, Coffey B, Cwik MF, Posner K, Wagner A, March JS, Riddle MA, Goldstein T, Curry J, Capasso L, Mayes T, Shen S, Gugga SS, Turner JB, Barnett S, Selazny J: Depressive symptoms and clinical status during the treatment of adolescent suicide attempters study (TASA). Journal of the American Academy of Child and Adolescent Psychiatry, 48: 997-1004, 2009. 123. Ghuman JK, Aman MG, Lecavalier L, Riddle M, Gelenberg A, Wright R, Rice S, Ghuman HS, Fort C: Randomized, placebo-controlled, crossover study of methylphenidate for attention-deficit/hyperactivity disorder symptoms in preschoolers with developmental disorders. Journal of Child and Adolescent Psychopharmacology, 19: 329-339, 2009. 124. Nestadt G, Di CZ, Riddle MA, Grados MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Knowles JA, Piacentini J, Pauls DK, Bienvenu OJ, Wang Y, Liang KY, Samuels JF, Roche KB: Obsessive-Compulsive Disorder: Sub-Classification based on Comorbidity. Psychological Medicine 39: 1491-1501, 2009.

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125. Bienvenu OJ, Wang Y, Shugart YY, Welch JW, Grados MA, Fyer AJ, Rauch SL, Murphy DL, McCracken JT, Rasmussen SA, Cullen B, Valle D, Hoehn-Saric R, Greenberg BD, Pinto A, Knowles JA, Piacentini J, Pauls DL, Liang KY, Riddle M, Samuels JF, Feng G, Nestadt G: Sapsap3 gene appears associated with pathological grooming in humans. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 150B: 710-720, 2009. 126. Shugart YY, Wang Y, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Liang KY, Nestadt G: Family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 150B: 886-892, 2009. 127. Wang Y, Samuels JF, Chang YC, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Hoehn-Saric R, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle MA, Shugart YY, Liang KY, Nestadt G: Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 2009; 150B:33-40. 128. Voyiaziakis E, Evgrafov O, Li D, Yoon HJ, Tabares P, Samuels J, Wang Y, Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang KY, Greenberg BD, Rasmussen SA, Murphy DL, Wendland JR, McCracken JT, Piacentini J, Rauch SL, Pauls DL, Nestadt G, Fyer AJ, Knowles JA: Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Molecular Psychiatry, 16:108-120, 2009. 129. dosReis S, McCulloch JR, Colantuoni E, Barnett SR, Pruitt D, Riddle MA, Zachik A: Early identification of seclusion and restraint patterns during adolescents’ course of residential treatment. Residential Treatment for Children & Youth 27: 160-174, 2010 130. Wang Y, Admaczyk A, Shugart YY, Samuels JF, Grados MA, Greenberg BD, Knowles JA, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Bienvenu OJ, Riddle M, Liang KY, Valle D, Wang T, Nestadt G: A screen of SLC1A1 for OCD-related alleles. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 153B: 635-639, 2010. 131. Voyiaziakis E, Evgrafov O, Li D, Yoon HJ, Tabares P, Samuels J, Wang Y, Riddle MA, Grados MA, Bienvenu OJ, Shugart YY, Liang KY, Greenberg BD, Rasmussen SA, Murphy DL, Wendland JR, McCracken JT, Piacentini J, Rauch SL, Pauls DL, Nestadt G, Fyer AJ, Knowles JA: Association of SLC6A4 variants with obsessive-compulsive disorder in a large multi-center US family study, Molecular Psychiatry 16: 108-120, 2011. 132. Bloom RM, Samuels JF, Grados MA, Chen Y, Bienvenu OJ, Riddle MA, Liang KY, Brandt J, Nestadt G: Cognitive functioning in compulsive hoarding. Behaviour Research and Therapy 25: 1139-1144, 2011. 133. Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Geller DA, Pauls DL, Liang KY, Nestadt G, Samuels JF: Separation Anxiety Disorder in OCD. Depression and Anxiety 28: 256-262, 2011.

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134. Bloom RM, Samuels JF, Riddle MA, Bienvenu OJ, Grados MA, Easton WW, Liang KY, Nestadt G: Association between a serotonin transporter promoter polymorphism (5-HTTLPR) and personality disorder traits in a community sample. Journal of Psychiatric Research 25: 1139-1144, 2011. 135. Samuels J, Wang Y, Riddle MA, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Grados MA, Knowles JA, Piacentini J, Cullen B, Bienvenu OJ, Rasmussen SA, Pauls DL, Shugart YY, Liang KY, Nestadt G: Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder: American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 156: 472-477, 2011. 136. Ginsburg GS, Keeton CP, Drazdowski TK, Riddle MA: The utility of clinicians ratings of anxiety using the Pediatric Anxiety Rating Scale (PARS). Child and Youth Care Forum 40, 93-105, 2011. 137. dosReis S, Yoon Y, Rubin DM, Riddle MA, Noll E, Rothbard A: Antipsychotic treatment among youth in foster care. Pediatrics, 128, e1459 – 66, 2011. 138. Bienvenu OJ, Samuels JF, Wuyek LA, Liang KY, Wang Y, Grados MA, Cullen BA, Riddle MA, Greenberg BD, Rasmussen SA, Fyer AJ, Pinto A, Rauch SL, Pauls DL, McCracken JT, Piacentini J, Murphy DL, Knowles JA, Nestadt G: Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective. Psychological Medicine 42: 1-13, 2012. 139. Nestadt G, Wang Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Rasmussen SA, Cullen B, Piacentini J, Geller D, Pauls D, Bienvenu OJ, Chen Y, Liang KY, Goes F, Maher B, Pulver A, Shugart YY, Valle D, Samuels JF, Chang C: Homeobox genes in obsessive-compulsive disorder. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics), 159B: 53-60, 2012. 140. Geller B, Luby JL, Joshi P, Wagner KD, Emslie G, Walkup JT, Axelson DA, Bolhofner K, Robb A, Wolf DV, Riddle MA, Birmaher B, Nusrat N, Ryan ND, Vitiello B,Tillman R, Lavori P: A randomized controlled trial of Risperidone, Lithium, or Valproate for initial treatment of Bipolar I Disorder, Manic or Mixed Phase, in children and adolescents. Archives in General Psychiatry, 69: 515-528, 2012. 141. Soto PL, Wilcox KM, Zhou Y, Ator NA, Riddle MA, Wong DF, Weed MR: Long-term exposure to oral methylphenidate of d-1 amphetamine mixture in peri-adolescent Rhesus monkeys: Effects on physiology, behavior, and dopamine system development. Neuropsychopharmacology, 37:2566-2579, 2012. 142. Stewart SE, Yu D, Scharf JM, Neale BM, Fagerness JA, Mathews CA, Arnold PD, Evans PD, Gamazon ER, Osiecki L, Haddad S, Crane J, Hezel D, Illman C, Mayerfeld C, Konkashbaev A, Liu C, Pluzhnikov A. Tikhomirov A, Edlund CK, Rauch SL, Moessner R, Falkai P, Maier W, Ruhrmann S, Grabe-H-J, Lennertz L, Wagner M, Bellodi L, Cavallini MC, Richter MA, Cook EH Jr, Kennedy JL, Rosenberg D, Stein DJ, Hemmings SMJ, Lochner C, Azzam A, Cnavira DA, Fournier E, Garrido H, Sheppard B, Umana P, Murphy DL, Wendland JR, Veeenstra-VanderWeele J, Denyse D, Blom R, Deforce D, Van Nieuwerburgh F, Westenberg HGM, Walitza S, Egberts K, Renner T, Miguel EC, Cappi C, Hounie AG, do Rosario MC, Sampaio AS, Vallada H, Nicolini H, Lanzagorta N, Camerena B, Delorme R, Leboyer M, Pato CN, Pato MT, Voyiaziakis E, Heutink P, Smot JH, Samuels J, Cullen B, Fyer AJ, Grados MA,

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Greenberg BD, McCracken JT, Riddle MA, Wang Y, Coric V, Leckman JF, Bloch M, Pittenger C, Eapen V, Black DW, Ophoff RA, Strengman E, Cusi D, Turiel M, Frau FF, Macciardi F, Gibbs JR, Singleton A, Hardy J, Crenshaw AT, Parkin MA, Mirel DB, Conti DV, Purcell S, Nestadt G, Hanna GL, Jenike MA, Knowles JA, Cox N, Pauls DL: Genome wide association study of OCD. Molecular Psychiatry, 1-11, 2012. 143. Vitiello B, Riddle MA, Yenokyan G, Axelson DA, Wagner KD, Joshi P, Walkup JT, Luby J, Birmaher B, Ryan ND, Emslie D, Robb A, Tillman R: Treatment moderators and predictors of outcome in the treatment of early age mania study (TEAM), Journal of the American Academy of Child and Adolescent Psychiatry, 51:867-78, 2012 144. Goes FS, McCusker MG, Bienvenu OJ, Mackinnon DF, Mondimore FM, Schweizer B, Depaulo JR, Potash JB: Co-morbid anxiety disorders in bipolar disorder and major depression: Familial aggregation and clinical characteristics of co-morbid panic disorder, social phobia, specific phobia and obsessive-compulsive disorder. Psychological Medicine, 42:1449-1459, 2012. 145. Gottfried RJ, Gerring JP, Machell K, Yenokyan G, Riddle MA: The Iron Status of Youth in a Community Mental Health Clinic is Lower than in a National Sample, Journal of Child and Adolescent Psychopharmacology, 23: 91-100, 2013. 146. Riddle MA, Yershova K, Lazzaretto D, Paykina N, Yenokyan G, Greenhill L, Abikoff H, Vitiello B, Wigal T, McCracken JT, Kollins SH, Murray DW, Wigal S, Kastelic E, McGough JJ, dosReis S, Bauzó-Rosario A, Stehli A, Posner K, and the PATS Study Group: The Preschool Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS) 6-Year Follow-up, Journal of the American Academy of Child and Adolescent Psychiatry, 52: 264-278, 2013. 147. Miller L, Riddle MA, Pruitt D, Zachik A, dosReis S: Antipsychotic Treatment Patterns and Aggressive Behavior Among Adolescents in Residential Facilities, Journal of Behavioral Health Services & Research, 40: 97-110, 2013. 148. Stewart SE, Mayerfeld C, Arnold PD, Crane JR, O’Dushlaine C, Fagerness JA, Schar, F Kassam JM, Moya PR, Wendland J, Delorme R, Richter MA, Kennedy JL, Veenstra-VanderWeele J, Samuels J, Greenberg BD, McCracken JT, Knowles JA, Fyer AJ, Rauch SL, MA Riddle, Grados MA, Bienvenu OJ, Cullen B, Wang Y, Shugart YY, Piacentini J, Rasmussen S, Nestadt G, Murphy DL, Cook EH, Pauls DL, Hanna GL, Mathews CA. Meta-Analysis of Association between Obsessive-Compulsive Disorder and the 3’ Region of Neuronal Glutamate Transporter SLC1A1, Am J Med Genet B Neuropsychiatr Genet, 162: 367-379, 2013. 149. Reeves GM, Keeton C, Correll CU, Johnson JL, Hamer RM, Sikich L, Hazzard L, Alderman C, Scheer A, Mabe M, Kapoor S, Sheridan E, Borner I, Bussell K, Pirmohamed S, Bethea TC, Chekuri R, Gottfried R, Reinblatt SP, Santana E, Riddle MA. Improving metabolic parameters of antipsychotic child treatment (IMPACT) study: rationale, design, and methods. Child Adolesc Psychiatry Ment Health. 7: 1-14, 2013 (on line). 150. Mattheisen M, Samuels, JF; Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller D,

Murphy DL, Knowles JA, Grados MA, Riddle MA, Rasmussen SA, McLaughlin NC, Qin H-D, Cullen B, Piacentini J, Pauls DL, Bienvenu OJ, Stewart SE, Liang K-Y, Fernando SG, Maher B, Pulver AE, Shugart Y-Y, Valle D, Lange C, Nestadt G. Genome Wide Association Study in

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Obsessive-Compulsive Disorder: Results from the OCGAS. Molecular Psychiatry. 18: 788-98, 2014. 151. Davis LK, Yu D, Keenan CL, Gamazon ER, Konkashbaev AI, Derks EM, Neale BM, Yang J, Lee SH, Evans P, Barr CL, Bellodi L, Benarroch F, Berrio GB, Bienvenu OJ, Bloch MH, Blom RM, Bruun RD, Budman CL, Camarena B, Campbell D, Cappi C, Cardona Silgado JC, Cath DC, Cavallini MC, Chavira DA, Chouinard S, Conti DV, Cook EH, Coric V, Cullen BA, Deforce D, Delorme R, Dion Y, Edlund CK, Egberts K, Falkai P, Fernandez TV, Gallagher PJ, Garrido H, Geller D, Girard SL, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Haddad S, Heiman GA, Hemmings SM, Hounie AG, Illmann C, Jankovic J, Jenike MA, Kennedy JL, King RA, Kremeyer B, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Liu C, Lochner C, Lowe TL, Macciardi F, McCracken JT, McGrath LM, Mesa Restrepo SC, Moessner R, Morgan J, Muller H, Murphy DL, Naarden AL, Ochoa WC, Ophoff RA, Osiecki L, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Rauch SL, Renner TJ, Reus VI, Richter MA, Riddle MA, Robertson MM, Romero R, Rosàrio MC, Rosenberg D, Rouleau GA, Ruhrmann S, Ruiz-Linares A, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Strengman E, Tischfield JA, Valencia Duarte AV, Vallada H, Van Nieuwerburgh F, Veenstra-Vanderweele J, Walitza S, Wang Y, Wendland JR, Westenberg HG, Shugart YY, Miguel EC, McMahon W, Wagner M, Nicolini H, Posthuma D, Hanna GL, Heutink P, Denys D, Arnold PD, Oostra BA, Nestadt G, Freimer NB, Pauls DL, Wray NR, Stewart SE, Mathews CA, Knowles JA, Cox NJ, Scharf JM. Partitioning the Heritability of Tourette Syndrome (TS) and Obsessive Compulsive Disorder (OCD) Reveals Differences In Genetic Architecture, PLOS Genetics. 9:1-14, 2014. 152. McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Sian M.J. Hemmings, Luis D. Herrera, Ana G. Hounie, Joseph Jankovic, James L. Kennedy, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle MA, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy number variation in obsessive-compulsive disorder and Tourette’s Syndrome: A cross disorder study. Journal of the American Academy of Child and Adolescent Psychiatry, 53: 910-919, 2014. 153. Reinblatt SP, Leoutsakos JS, Mahone EM, Forrester S, Wilcox HC, Riddle MA: Association between binge eating and attention-deficit/hyperactivity disorder (ADHD) in two pediatric community mental health clinics. International Journal of Eating Disorders, 48:505-511, 2014.

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154. Samuels J, Yao Y, Wang Y, Grados M, Bienvenu J, Pinto A, Rauch S, Greenberg M, Knowles J, Fyer A, Piacentini J, Pauls D, Goggins B, Rasmussen S Stewart E, Geller D, Maher B, Goes F, Murphy D, McCracken J, Riddle MA, Nestadt G. Clinical Correlates and Genetic Linkage of Social and Communication Difficulties in Families with Obsessive-Compulsive Disorder: Results from the OCD Collaborative Genetics Study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 16B:326-336, 2014. 155. Samuels J, Grados MA, Riddle MA, Bienvenu OJ, Goes FS, Cullen B, Wang Y, Greenberg BD, Fyer AJ, McCracken JT, Geller D, Murphy DL, Knowles JA, Rasmussen SA, McLaughlin NC, Piacentini J, Pauls DL, Stewart SE, Shugart YY, Maher B, Pulver AE, Nestadt G. Hoarding in Children and Adolescents with Obsessive-Compulsive Disorder. Journal of Obsessive-Compulsive and Related Disorders, 3:325-331, 2014. 156. Crosby Budinger M, Cwik M, Riddle MA: Awareness, attitudes and use of crisis hotlines among youth at risk for suicide. Suicide and Life Threatening Behavior, 45: 192-198, 2015. 157. Rynn, MA, Walkup, JT, Compton, SN, Sakolsky, D, Sherrill, JT, Shen, S, Kendall, PC, McCracken, JT, Albano, AM, Piacentini, JC, Riddle, M, Keeton, C, Waslick, BD, Chrisman, A, Axelson, D, Iyengar, S, March, JS, Birmaher, B. Child/Adolescent Anxiety Multimodal Study: Evaluating Safety. Journal of the American Academy of Child and Adolescent Psychiatry, 54:180-190, 2015. 158. Yu D et al. (Riddle MA is 104 of 155): Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship between Tourette Syndrome and Obsessive-Compulsive Disorder. American Journal of Psychiatry, 172:82-93, 2015. 159. Qin H, Samuels JF, Wang Y, Zhu Y, Grados MA, Riddle MA, Greenberg BD, Knowles JA, Fyer AJ, McCracken JT, Murphy DL, Rasmussen SA, Cullen BA, Piacentini J, Geller D, Stewart SE, Pauls D, Bienvenu OJ, Goes FS, Maher B, Pulver AE, Valle D, Lange C, Mattheisen M, McLaughlin NC, Liang K-Y, Nurmi EL, Askland KD, Nestadt G, Shugart YY: Whole genome association analysis of treatment response in obsessive-compulsive disorder. Molecular Psychiatry, 1-7, 2015. 160. Reinblatt SP, Mahone EM, Tanofsky-Kraff M, Lee-Winn A, Yenokyan G, Leoutsakos JS, Moran TH, Guarda AS, Riddle MA: Pediatric loss of control eating syndrome: Association with attention deficit/hyperactivity disorder and impulsivity. International Journal of Eating Disorders, 48:580-588, 2015. 161. Vitiello B, Lazzaretto D, Yershova K, Abikoff H, Paykina N, McCracken JT, McGough JJ, Kollins SH, Greenhill LL, Wigal S, Wigal T, Riddle MA: Pharmacotherapy of the Preschool ADHD Treatment Study (PATS) children growing up. Journal of the American Academy of Child & Adolescent Psychiatry, 54:550-556, 2015. 162. Walkup JT, Wagner KD, Miller L, Yenokyan G, Luby J, Joshi P, Axelson D, Robb A, Salpekar J, Wolf D, Sanyal A, Birmaher B, Vitiello B, Riddle MA: Treatment of Early Age Mania: Outcomes for Partial and Nonresponders to Initial Treatment. Journal of the American Academy of Child and Adolescent Psychiatry, 54:1008-1019, 2015. 163. Salpekar JA, Joshi PT, Axelson DA, Reinblatt SP, Yenokyan G, Sanyal A, Walkup JT, Vitiello B, Luby JL, Wagner KD, Nusrat N, Riddle MA: Depression and Suicidality

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Outcomes in the Treatment of Early Age Mania Study. Journal of the American Academy of Child and Adolescent Psychiatry, 54:999-1007, 2015 164. Reeves GM, Wehring HJ, Connors KM, Bussell K, Schiffman J, Medoff DR, Tsuji T, Walker J, Brown A, Strobeck D, Clough T, Rush CB, Riddle MA, Love RC, Zachik A, Hoagwood K, Olin S, Stephan S, Okuzawa N, Edwards S, Baquet C, dosReis S: The family VOICE (Value of Information, Community Support, and Experience Study): Rationale, design, and methods of a “family-centered” research study. Journal of Nervous and Mental Disease, in press. 165. Ginsburg GS, Drake KL, Tein J, Teetsel R, Riddle MA: Preventing the onset of anxiety disorder in offspring of anxious parents: One year follow-up of a family-based intervention, American Journal of Psychiatry, in press. 166. Riddle MA, Maher BS, Wang Y, Grados M, Bienvenu OJ, Goes FS, Cullen B, Murphy DL, Rauch SL, Greenberg BD, Knowles JA, McCracken JT, Pinto A, Fyer AJ, Piacentini J, Pauls DL, Rasmussen SA, Shugart YY, Nestadt G, Samuels J: Obsessive compulsive personality disorder nosology: Evidence for two dimensions, Depression and Anxiety, in press. 167. Mroczkowski MM, Goes FS, Riddle MA, Grados MA, Bienvenu OJ, Greenberg BD, Fyer AJ, McCracken JT, Rauch SL, Murphy DL, Knowles JA, Piacentini J, Cullen B, Rasmussen SA, Pauls DL, Nestadt G, Samuels J: Dependent Personality, Separation Anxiety Disorder, and other Anxiety Disorders in OCD. Personality and Mental Health, in press. 168. Park JM, Samuels JF, Grados MA, Riddle MA, Bienvenu OJ, Goes FS, Cullen B,

Wang Y, Krasnow J, Murphy DL, Rasmussen SA, McLaughlin NC, Piacentini J, Pauls

DL, Stewart SE, Shugart YY, Maher B, Pulver AE, Knowles JA, Greenberg BD, Fyer AJ,

McCracken JT, Nestadt G, Geller DA: ADHD and Executive Functioning Deficits in

Children who Hoard. Journal of the American Academy of Child and Adolescent

Psychiatry, submitted.

169. The ENIGMA and IOCDF-GC Consortium, Hibar DP, ...Riddle MA,… IOCDF-GC, ENIGMA2, Stewart E, van den Heuvel OA, Pauls DL, Knowles JA, Stein DJ, Thompson

PM: Significant concordance of the genetic variation that increases both the risk for OCD and the volumes of the nucleus accumbens and putamen. Nature Neuroscience, in press. 170. Miller L at al….IPT-DMDD…submitted.

171. Samuels JF et al….Doubt in OCD….submitted.

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II. Peer Reviewed Scientific Articles: Letters and Case Reports 1. Riddle MA, Hardin MT, Towbin KE, Leckman JF, Cohen DJ: Tardive dyskinesia following haloperidol treatment for Tourette’s syndrome (letter). Archives of General Psychiatry, 44:98-99, 1987. 2. Riddle MA, Leckman JF, Hardin MT, Anderson GM, Cohen DJ: Fluoxetine treatment of obsessions and compulsions in patients with Tourette’s syndrome (letter). American Journal of Psychiatry, 145:1173-1174, 1988. 3. Riddle MA, Brown N, Dzubinski D, Jetmalani AJ, Law Y, Woolston JL: Fluoxetine overdose in an adolescent. Journal of the American Academy of Child and Adolescent Psychiatry, 28:587-588, 1989. 4. Leckman JF, Goodman WK, Riddle MA, Hardin MT, Anderson GM: Low CSF 5-HIAA and obsessions of violence: Report of two cases. Psychiatry Research, 33:95-99, 1990. 5. King RA, Anderson GM, Rasmusson A, Riddle MA: Reply to letter of Drs. Fuller and Beasley (letter). Journal of the American Academy of Child and Adolescent Psychiatry, 30:849, 1991. 6. Riddle MA, Nelson JC, Kleinman CS, Rasmusson A, Leckman JF, King RA, Cohen DJ: Sudden death in children receiving Norpramin®: A review of three reported cases and commentary. Journal of the American Academy of Child and Adolescent Psychiatry, 30:104-108, 1991. 7. Anderson GM, Pollak ES, Chatterjee D, Leckman JF, Riddle MA, Cohen DJ: Brain monoamines and amino acids in Gilles de la Tourette’s Syndrome: A preliminary study of subcortical regions (letter). Archives of General Psychiatry, 49:584-586, 1992. 8. Riddle MA, Geller B, Ryan N: Another sudden death in a child treated with desipramine. Journal of the American Academy of Child and Adolescent Psychiatry, 32:792-797, 1993. 9. Riddle MA, Geller B, Ryan N: Reply to Letter of Dr. Werry (letter). Journal of the American Academy of Child and Adolescent Psychiatry, 33:589-590, 1994. 10. Van Wattum PA, Anderson GM, Chappell PB, Goodman WK, Riddle MA, Leckman JF: Cerebrospinal fluid Dynorphin A[1-8] and ß-Endorphin levels in Tourette’s syndrome are unaltered (letter). Society of Biological Psychiatry, 45:1527-1528, 1999. 11. Bhangoo RK, Riddle MA: Pharmacologic treatment of anxiety disorders in adolescents. Adolescent Psychiatry, 24:243-270, 1999. 12. Labellarte MJ, Walkup JT, Riddle MA: Benign U-wave mistaken for QTc prolongation (letter). Journal of the American Academy of Child and Adolescent Psychiatry 42: 621, 2003. 13. Riddle MA: Paroxetine and the FDA. Journal of the American Academy of Child and Adolescent Psychiatry 43: 127-130, 2004. (Letter to the Editor, Reply) 14. Courvoisie HE, Cooke D, Riddle M: Case Study: Olanzapine induced diabetic ketosis in a seven-year-old boy. Journal of Child and Adolescent Psychopharmacology 14: 612-616, 2004.

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15. Reinblatt SP and Riddle MA: Selective serotonin reuptake inhibitor-induced apathy: a pediatric case series. Journal of Child and Adolescent Psychopharmacology 16: 227-233, 2006. 16. Grados, MA, Samuels J, Shugart YY, Willour VL, Wang Y, Cullen B, Bienvenu OJ, Hoehn-Saric R, Valle D, Liang KY, Riddle MA, Wendland JR, Murphy DL, Nestadt G, Detera-Wadleigh S: Rare Plus Common SERT Variants in Obsessive-Compulsive Disorder (OCD). (Letter) Molecular Psychiatry 12: 422-423, 2007. 17. Rodowski MF, Cagande CC, Riddle MA: Case Report: Childhood Obsessive-Compulsive Disorder presenting as schizophrenia spectrum disorders. Journal of Child and Adolescent Psychopharmacology 18: 395-403, 2008. 18. Burkey MD, Howell CJ, Riddle MA: Antipsychotic-induced psychotic-like syndrome. Journal of Child and Adolescent Psychopharmacology 22: 92-95, 2012. 19. JF Samuels, MA Riddle, BD Greenberg, AJ Fyer, JT McCracken: Studies on the interaction between mianserin and noradrenaline in patients suffering from depressive illness. British Journal of Clinical Pharmacology 4: 712-714, 2012. 20. Vitiello B, Riddle MA, Yenokyan G, Axelson DA, Birmaher B, Ryan ND, Emslie G: Another Look at the Treatment of Early-Age Mania (TEAM) Trial: Reply. Journal of the American Academy of Child and Adolescent Psychiatry 52: 206-207, 2013.

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III. Editorials, Reviews and Commentaries 1. Riddle MA: Leckman JF, Anderson GM, Hardin MT, Ort SI, Towbin KE, Shaywitz BA, Cohen DJ: Assessment of dopaminergic function in children and adults: Long and brief debrisoquin administration combined with plasma homovanillic acid. Psychopharmacology Bulletin, 23:411-414, 1987. 2. Riddle MA: Research on a children’s psychiatric inpatient service. Journal of the American Academy of Child and Adolescent Psychiatry, 28:42-46, 1989. 3. Goodman WG, McDougle CJ, Price LH, Riddle MA, Pauls DL, Leckman JF: Beyond the serotonin hypothesis: A role for dopamine in some forms of obsessive compulsive disorder? The Journal of Clinical Psychiatry, 51:36-43, 1990. 4. Scahill L, Riddle MA: Psychiatrically hospitalized children: A critical review. Yale Journal of Biology and Medicine, 63:301-312, 1990. 5. Riddle MA: Editorial: Neuroleptic malignant syndrome in children and adolescents: Time to stop, look, and listen. Journal of Child and Adolescent Psychopharmacology, 2:155-156, 1992. 6. The Tourette Syndrome Classification Study Group (Fahn S, Bruun RD, Caine E, Cohen DJ, Comings DE, Como PG, Conneally M, Gancher ST, Golden GS, Jankovic J, Kurlan R, LeWitt P, Pauls DL, Riddle MA, Shapiro AK, Singer HS): Definitions and classification of tic disorders. Archives of Neurology, 50:1013-1016, 1993. 7. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McDougle CJ, Barr LC, Cohen DJ: The role of central oxytocin in obsessive compulsive disorder and related normal behavior. Psychoneuroendocrin, 19:723-749, 1994. 8. Leonard H, Jensen PS, Vitiello B, Ryan N, March J, Riddle MA, Biederman J: Ethical issues in psychopharmacological treatment research with children and adolescents. Ethical issues in mental health research with children and adolescents, 73-88, 1996. 9. Riddle, MA, Walkup JT: Anxiety disorders in children and adolescents. Review of Psychiatry, 15:379-382, 1996. 10. Grados M, LaBuda M, Riddle M, Walkup J: Obsessive compulsive disorder in children and adolescents. International Journal of Psychiatry, 9:83-97, 1997. 11. Greenhill LL, Pine D, March J, Birmaher B, Riddle MA: Assessment issues in treatment research of pediatric anxiety disorders: What is working, what is not working, what is missing, and what needs improvement. Psychopharmacology Bulletin, 34:155-164, 1997. 12. Walkup JT, Labellarte MJ, Riddle MA: Commentary: Unmasked and uncontrolled medication trials in child and adolescent psychiatry. Journal of the American Academy of Child and Adolescent Psychiatry, 37:360-363, 1998. 13. Riddle MA, Subramaniam G, Walkup J: Efficacy of psychiatric medications in children and adolescents: A review of controlled studies. Psychiatric Clinics of North America: Annual Review of Drug Therapy, 5:269-285, 1998.

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14. Riddle MA, Labellarte MJ, Walkup JT: Pediatric psychopharmacology: Problems and prospects. Journal of Child and Adolescent Psychopharmacology, 8(2):87-97, 1998. 15. Riddle M: Obsessive-compulsive disorder in children and adolescents. British Journal of Psychiatry, 173(suppl. 25):91-96, 1998. 16. Riddle MA, Bernstein GA, Cook E, Leonard H, March JS, Swanson J: Anxiolytics, Adrenergic Agents, and Naltrexone. Journal of the American Academy of Child and Adolescent Psychiatry, 38:546-556, 1999. 17. Geller B, Biederman J, Leonard H, Riddle M, Spencer T, Walsh T, Wilens T: Critical review of tricyclic antidepressant use in children and adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 38:513-516, 1999. 18. Riddle MA: Third International Obsessive-Compulsive Disorder Conference: Childhood and OCD. CNS Spectrums Academic Supplement, 4(5) Supplement 3, 13-15, 1999. 19. NIH Consensus Development Panel on Rehabilitation of Persons with Traumatic Brain Injury (Ragnarson KT, Riddle M, et al.): Rehabilitation of persons with traumatic brain injury. Journal of the American Medical Association, 282(10):974-983, 1999. 20. Labellarte MJ, Ginsburg GS, Walkup JT, and Riddle MA: The treatment of anxiety disorders in children and adolescents. Biological Psychiatry, 46:1567-1578, 1999. 21. Riddle MA: Commentary: Subtypes of obsessive compulsive disorder? World Psychiatry Association Series, Evidence and Experience in Psychiatry, 4:23-26, 2000. 22. Leckman JF, Riddle MA: Tourette’s Syndrome: When habit forming systems form habits of their own? Neuron, 28:349-354, 2000. 23. Labellarte MJ, Kaplan D, Frosch E, Riddle MA: The treatment of pediatric anxiety disorders. The Economics of Neuroscience 2:58-61, 2000. 24. Pine DS, Riddle MA, Klein R, Kutcher SP: Diagnosis and treatment of anxiety disorders in children. Primary Psychiatry 7:39-43, 2000. 25. Riddle MA, Kastelic EA, Frosch E: Pediatric psychopharmacology. Journal of Child Psychology and Psychiatry and Applied Disciplines, 42:73-90, 2001. 26. Grados MA, Riddle MA: Pharmacological treatment of childhood OCD: From theory to practice. Journal of Clinical Child Psychology, 30:67-79, 2001. 27. Greenhill LL, Vitiello B, Abikoff H, Levine J, March JS, Riddle MA, Capasso L, Cooper T, Davies M, Fisher P, Findling RL, Fried J, Labellarte M, McCracken J, McMahon DJ, Robinson J, Skrobala AM, Scahill L, Walkup J, Zito J: Adverse drug events and adverse drug reactions in pediatric patients: Part IV. Current Therapeutic Research 62:873-884, 2001. 28. Nestadt G, Samuels JF, Riddle MA, Bienvenu OJ, Liang KY, Grados MA, Cullen B: Obsessive-compulsive disorder: Defining the phenotype. Journal of Clinical Psychiatry 63:5-7, 2001.

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29. Riddle MA, Carlson J: Clinical psychopharmacology for Tourette syndrome and associated disorders. Advances in Neurology, 85:343-354, 2001. 30. Nestadt G, Addington A, Samuels J, Bienvenu J, Grados M, Riddle M, Liang KY, Cullen B, Hoehn-Saric R: Reply. Biological Psychiatry 55(9): 961, 2004. 31. Kowatch RA, Fristad M, Birmaher B, Wagner KD, Findling RL, Hellander M, and the Workgroup Members: Treatment Guidelines for Children and Adolescents with Bipolar Disorder: Child Psychiatric Workgroup on Bipolar Disorder. J American Academy of Child and Adolescent Psychiatry 44: 213-239, 2005. 32. Riddle MA: The Pharmaceutical Industry, Academic Medicine and the FDA: Commentary by an Academic Child and Adolescent Psychiatrist. Journal of Child and Adolescent Psychopharmacology 17: 300-302, 2007. 33. Riddle MA: Guest Editorial: New Findings from the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology 17: 543-546, 2007. 34. Reinblatt SP, Riddle MA: The pharmacological management of childhood anxiety disorders: A review. Psychopharmacology, 191:67-86, 2007. 35. Riddle MA, Walkup JA: Attention-deficit hyperactivity disorder: a view from the USA. Nature Clinical Practice Neurology, 4: 118-119, 2008. 36. Riddle MA, Walkup JT, Vitiello B: Introduction: Issues and viewpoints in pediatric psychopharmacology. International Review of Psychiatry 20: 119-120, 2008. 37. Grados M, Riddle MA: Do all obsessive-compulsive disorder subtypes respond to medication? International Review of Psychiatry 20: 189-193, 2008. 38. Grados MA, Riddle MA: Editorial: Two Times Four is Four: OCD Dimensions, Classes and Categories. Journal of American Academy of Child and Adolescent Psychiatry 47(7): 731-733, 2008. 39. Miller L, Riddle MA: Venlafaxine extended release in pediatric anxiety and depression. Pediatric Health 2: 279-288, 2008. 40. Riddle MA: Psychopharmacologic Perspective. DSM-IV-TR Casebook and Treatment Guide for Child Mental Health. Galanter CA, Jensen PS (eds) American Psychiatric Publishing, Arlington VA : 204-207, 2009. 41. Correll CC, Sikich L, Reeves G, Riddle MA: Metformin for antipsychotic-related weight gain and metabolic abnormalities: When, for whom and for how long? American Journal of Psychiatry, 170:9, 2013.

42. Reeves GM, Riddle MA: A practical and effective primary care intervention for treating adolescent depression. Journal of the American Medical Association, 312:797-798, 2014.

43. Andres M, Paramjit J, Block M, Riddle MA, Rogers C: Hats off: 2014 Journal awards. Journal of the American Academy of Child and Adolescent Psychiatry, submitted.

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44. Galanter, B and Jensen, PS: DSM-5 casebook (Psychopharmacologic Perspective), in press.

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IV. Book Chapters 1. Cohen DJ, Riddle MA, Laor N, Young JG, Shaywitz BA: Neurobiological perspectives on neuropsychiatric disorders of childhood. In: Psychopharmacology, Vol. 1, Part 2: Clinical Psychopharmacology, H Hippius, G Winokur (eds). Amsterdam: Excerpta Medica, pp. 53-73, 1983. 2. Cohen DJ, Riddle MA, Leckman JF, and Shaywiz BA: Tourette Syndrome. In: Neuropsychiatric Movement Disorders, DV Jeste, RJ Wyatt (eds). Washington, D.C.: American Psychiatric Press, pp. 19-52, 1984. 3. Riddle MA, Vitulano LA: Group psychotherapy for children and adolescents. In: Psychiatry, JO Cavenar, R Michels (eds). Philadelphia: JB Lippincott Company, Vol. 2, Section 1, Chapter 63, 1-7, 1985. 4. Leckman JF, Cohen DJ, Price RA, Riddle MA, Mindera RB, Anderson GM, Pauls DL: The pathogenesis of Tourette Syndrome: A review of data and hypotheses. In: Movement Disorders, NS Shah and AG Donald (eds). New York: Plenum Medical Book Company, 257-272, 1986. 5. Cohen DJ, Riddle MA, Leckman JF: Tourette syndrome: Clinical features, etiology, and pathogenesis. In: Basic Handbook of Child Psychiatry: Advances and New Directions, Vol V, JD Call, RL Cohen, SI Harrison, IN Berlin, LA Stone (eds). New York: Basic Books, 319-327, 1987. 6. Cohen DJ, Riddle MA, Leckman JF: Tourette syndrome: Assessment and management. In: Basic Handbook of Child Psychiatry: Advances and New Directions, Vol V, JD Call, RL Cohen, SI Harrison, IN Perlin, LA Stone (eds). New York: Basic Books, 462-469, 1987. 7. Riddle MA: Individual and parental psychotherapy in autism: In: Handbook of Autism and Pervasive Developmental Disorders, DJ Cohen, AM Donnellan (eds). New York: V.H. Winston & Sons, 528-541, 1987. 8. Leckman JF, Walkup J, Riddle MA, Towbin KE, Cohen DJ: Tic Disorders. In: Psychopharmacology, The Third Generation of Progress, HY Meltzer, (ed). New York: Raven Press, 1239-1246, 1987. 9. Riddle MA, Cohen DJ, Shaywitz BA, and Shaywitz SE: Neuropsychiatric problems in children treated for leukemia: An iatrogenic model of attention deficit disorder? In: Advances in Human Psychopharmacology, Vol.4, GD Burrows, JS Werry (eds). Greenwich, CT: JAI Press, 53-75, 1987. 10. Leckman JF, Riddle MA, Cohen DJ: Pathobiology of Tourette’s syndrome. In: Tourette’s Syndrome: Clinical Understanding and Treatment. CJ Cohen, RD Bruun, JF Leckman (eds). New York: John Wiley & Sons, 103-116, 1988. 11. Riddle MA, Hardin MT, Ort SI, Leckman JF, Cohen DJ: Behavioral symptoms in Tourette’s Syndrome. In: Tourette’s Syndrome: Clinical Understanding and Treatment. DJ Cohen, RD Bruun, JF Leckman (eds). New York: John Wiley & Sons, 151-162, 1988.

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12. Cohen DJ, Ort SI, Leckman JF, Riddle MA, Hardin MT: Family functioning and Tourette’s Syndrome. In: Tourette’s Syndrome: Clinical Understanding and Treatment. DJ Cohen, RD Bruun, JF Leckman (eds). New York: John Wiley & Sons, 179-196, 1988. 13. Towbin KE, Riddle MA, Leckman JF, Bruun RD, Cohen DJ: The Clinical care of individuals with Tourette’s Syndrome. In: Tourette’s Syndrome: Clinical Understanding and Treatment. DJ Cohen, RD Bruun, JF Leckman (eds). New York: John Wiley & Sons, 329-352, 1988. 14. Riddle MA, Cho SC: Elimination disorders. In: Treatments of Psychiatric Disorders: A Task Force Report of the American Psychiatric Association, Vol.I, TB Karasu (Ed). Washington, D.C.: American Psychiatric Press, 717-730, 1989. 15. Riddle MA, Cho SC: Biological aspects of adolescent depression. In: Biology of Adolescent Behavior and Development, GR Adams, R Montemayor, TP Gulletta (eds). New York: Sage Publications, 223-246, 1989. 16. Rasmusson A, Riddle MA, Anderson GM, Leckman JF, Cohen DJ: Neurotransmitter assessment in neuropsychiatric disorders of childhood. In: Application of Basic Neuroscience to Child Psychiatry, S Deutsch, A Weizman, R Weizman (eds). New York: Plenum Publishing Corporation, 33-59, 1990. 17. Towbin KE, Riddle MA: Obsessive compulsive disorder. In: Child and Adolescent Psychiatry: A Comprehensive Textbook, M.Lewis (ed). Baltimore: Williams & Wilkins, 685-697, 1991. 18. Riddle MA: Psychotropic drug disposition in children and adolescents. In: Child and Adolescent Psychiatry: A Comprehensive Textbook, M.Lewis (ed). Baltimore: Williams & Wilkins, 767-770, 1991. 19. Riddle MA, Towbin KE: Obsessive compulsive disorder. In: Pediatrics, Nineteenth Edition, A. Rudolph (ed). Norwalk, CT Appleton & Lange, 120-121, 1991. 20. Towbin KE, Riddle MA, Leckman JF, Cohen DJ: The diagnosis and assessment of tic disorders. In: Child Psychopathology: Diagnostic Criteria and Clinical Assessment, S.R. Hooper, G.W. Hynd, R.E. Mattison (eds). New Jersey: Lawrence Erlbaum Associates, 343-377, 1992. 21. Cohen DJ, Riddle MA, Leckman JF: Pharmacotherapy of Tourette’s Syndrome and Associated Disorders. In: Psychiatric Clinics of North America, Vol. 15, D Shaffer (Ed.). Philadelphia, PA: W.B. Saunders Company, 109-130, 1992. 22. Leckman JF, Pauls DL, Peterson BS, Riddle MA, Anderson GM, Cohen DJ: Pathogenesis of Tourette syndrome: Clues from the clinical phenotype and natural history. In: Advances in Neurology-Tourette Syndrome: Genetics, Neurobiology, & Treatment, TN Chase, AJ Friedhoff, DH Cohen (eds.). New York: Raven Press, 15-24, 1992. 23. Anderson GM, Pollak ES, Chatterjee D, Leckman JF, Riddle MA, Cohen DJ: Postmortem analysis of subcortical monoamines and amino acids in Tourette syndrome. In: Advances in Neurology-Tourette Syndrome: Genetics, Neurobiology, and Treatment, TN Chase, AJ Friedhoff, DJ Cohen (eds.). New York: Raven Press, 123-133, 1992.

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24. Riddle MA, Rasmusson AM, Woods SW, Hoffer PB: SPECT imaging of cerebral blood flow in Tourette syndrome. In: Advances in Neurology-Tourette Syndrome: Genetics, Neurobiology, & Treatment, TN Chase, AJ Friedhoff, DJ Cohen (eds.). New York: Raven Press, 207-211, 1992. 25. Chappell PB, Leckman JF, Riddle MA, Anderson GA, Listwack SJ, Ort SI, Hardin MT, Scahill LD, Cohen DJ: Neuroendocrine and behavioral effects of naloxone in Tourette syndrome. In: Advances in Neurology-Tourette Syndrome: Genetics, Neurobiology & Treatment, TN Chase, AJ Friedhoff, DJ Cohen (eds.). New York: Raven Press, 253-262, 1992. 26. King RA, Riddle MA, Goodman WK: Psychopharmacology of obsessive compulsive disorder in Tourette’s syndrome. In: Advances in Neurology-Tourette Syndrome: Genetics, Neurobiology & Treatment, TN Chase, AJ Friedhoff, DJ Cohen (eds.). New York: Raven Press, 283-291, 1992. 27. Towbin KE, Riddle MA: Attention deficit hyperactivity disorder. In: Handbook of Tourette’s Syndrome and Related Tic and Behavioral Disorders, R Kurlan (ed.). New York: Marcel Dekker, 89-110, 1993. 28. King RA, Vitulano LA, Riddle MA: The treatment of obsessive-compulsive behavior. In: Handbook of Tourette’s Syndrome and Related Tic and Behavioral Disorders, R Kurlan (ed.). New York: Marcek Dekker, 401-422, 1993. 29. Walkup J, Scahill LD, Riddle MA: Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette’s syndrome. In: Behavioral Neurology of Movement Disorders, WJ Weiner & AE Lang (eds.). New York: Raven Press, 259-272, 1995. 30. Clein PD & Riddle MA: Pharmacokinetics in children and adolescents. In: MA Riddle (ed.), Child & Adolescent Psychiatric Clinics of North America. Philadelphia: W.B. Saunders Co., Vol 4:1, 59-75, 1995. 31. Zito JM & Riddle MA: Psychiatric pharmacoepidemiology for children. In MA Riddle (ed.), Child & Adolescent Psychiatric Clinics of North America. Philadelphia: W.B. Saunders Co., Vol 4:1, 77-95, 1995. 32. Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. In: MA Riddle (ed.), Child & Adolescent Psychiatric Clinics of North America. Philadelphia: W.B. Saunders Co., Vol 4:1, 197-216, 1995. 33. Riddle MA & Walkup JT: Tourette’s Syndrome. In: Current Therapy in Neurological Diseases, Fifth Edition, JW Griffin, RT Johnson (eds.). Mosby-Year Book, Inc., 290-294, 1996. 34. Towbin KE & Riddle MA: Obsessive-Compulsive disorder. In: Child and Adolescent Psychiatry: A Comprehensive Textbook, Second Edition, M.Lewis (ed.). Baltimore: Williams & Wilkins, 684-693, 1996. 35. Clein PD & Riddle MA: Pharmacokinetics in children and adolescents. In: Child and Adolescent Psychiatry: A Comprehensive Textbook, Second Edition, M. Lewis (ed.). Baltimore: Williams & Wilkins, 765-772, 1996.

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36. Walkup J & Riddle MA: Tic disorders. In: Psychiatry, A Tasman, J Kay, JA Lieberman (eds.). Philadelphia: W.B. Saunders Co., 702-719, 1996. 37. Riddle MA, Walkup JT (eds.): Anxiety Disorders in Children and Adolescents (for 5 chapters Foreward and Afterword). In: American Psychiatric Press Review of Psychiatry, Vol 15, LJ Dickstein, JM Oldham, MB Riva (eds.) pp. 379-381, 1996. 38. Cohen DJ, Leckman JF, Riddle MA: Tourette’s disorder and tic disorders. In: J Noshpitz (ed.), Handbook of Child and Adolescent Psychiatry, Volume 4. New York: John Wiley & Sons, Inc., 452-461, 1997. 39. Woolston JL, Rosenthal SL, Riddle MA, Sparrow SS, Cicchetti D, Zimmerman LD, Zoob I: 35/Acute and chronic brain syndrome in the school-age child. In: Handbook of Child and Adolescent Psychiatry: The Grade School Child: Development and Syndromes, 2, 401, 1997. 40. Walkup JT, Amos TM, Riddle MA: Tics and Tourette syndrome. In: CE Coffey & RA Brumback (eds.), Textbook of Pediatric Neuropsychiatry, Washington, DC: American Psychiatric Press, Inc., 939-959, 1998. 41. Labellarte MJ, Walkup JT, Riddle MA: The new antidepressants: Selective serotonin reuptake inhibitors. In: R Findling & J Blumer, eds., Child and Adolescent Psychopharmacology, Pediatric Clinics of North America, Philadelphia: W.B. Saunders Co., Vol. 45, 1137-1155, 1998. 42. Grados MA & Riddle MA: Obsessive-compulsive disorder in children and adolescents. In: CNS Drugs, Adis International Limited, 257-277, 1999. 43. Velosa JF & Riddle MA: Pharmacoloic treatment of anxiety disorders in children and adolescents. In: Child and Adolescent Psychiatry Clinics of North America. Philadelphia: W.B. Saunders Co., Volume 9, Number 1, 2000. 44. Riddle MA & Carlson J: Clinical pharmacology for Tourette Syndrome and associated disorders. In: D Cohen, C Goetz & J Jankovic, eds., Tourette Syndrome and Associated Disorders. Philadelphia: Lippincott Williams & Williams, 2000. 45. Kastelic EA, Labellarte MJ and Riddle MA: Selective serotonin reuptake inhibitors for children and adolescents. Current Psychiatry Reports 2: 117-123, 2000. 46. Courvoisie H, Labellarte M, Riddle MA: Psychosis in children: diagnosis and treatment. Dialogues in Clinical Neuroscience 3: 79-92, 2001. 47. Towbin KE & Riddle MA: Obsessive-compulsive disorder. In: Child and Adolescent Psychiatry: A Comprehensive Textbook, Third Edition, M. Lewis ed., Baltimore: Lippincott, Williams & Wilkins, in 834-847, 2002. 48. Barnett S & Riddle MA: Anxiolytics: Benzodiazepines, Buspirone, and Others. In A Martin, L Scahill, D Charney & JF Leckman, eds., Pediatric Psychopharmacology Principles and Practice, 27: 341-352, Oxford University Press, 2003. 49. Walkup JT, Riddle MA: Childhood disorders: Tic disorders. In: Psychiatry, 2nd Edition. A. Tasman, J Kay, JA Lieberman eds., England, John Wiley & Sons Ltd. 821-841, 2003.

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50. Barnett S and Riddle M: Conduct Disorder. In: Treatment of Pediatric Neurologic Disorders, HS Singer, EH Kossoff, AL Hartman, TO Crawford, eds., Boca Raton, Florida, Taylor & Francis Group. 513-518, 2005. 51. Towbin KE & Riddle MA: Obsessive-Compulsive Disorder. In: Lewis’s Child and Adolescent Psychiatry: A Comprehensive Textbook, Fourth Edition (L4), A. Martin, F.R. Volkmar eds., Baltimore: Lippincott, Williams & Wilkins, Chapter 5.5.2: 548-566, 2007. 52. Larson J, dosReis S, Matthys M, Riddle M: Medication resistant anxiety disorders in children and adolescents. In D. McKay & E. Storch (eds.) Handbook of Child and Adolescent Anxiety Disorders. Springer Publishers, New York, Chapter 24: 355-370, 2011. 53. Barnett S & Riddle MA: Anxiolytics and Sedative/Hyponotics: Benzodiazepines, Buspirone, and Others. In A Martin, L Scahill & C Kratchovil, eds: Pediatric Psychopharmacology Principles and Practice, 2nd edition, Oxford Press, Chapter 24, 338-349, 2011. 54. Gottfried R, Frosch E, Riddle MA: Antidepressants II: Other Antidepressants. In A Martin, L Scahill & C Kratchovil, eds: Pediatric Psychopharmacology Principles and Practice, 2nd edition, Oxford Press, Chapter 21: 286-296, 2011. 55. Riddle MA, dosReis S, Reeves GM, Wissow LS, Pruitt DB, Foy JM: Pediatric Psychopharmacology in Primary Care: A Conceptual Framework. Adolescent Medicine: State of the Art Reviews (American Academy of Pediatrics), Volume 24, 371-390, 2013. 56. Riddle MA, dosReis S, Reeves GM, Wissow LS, Pruitt DB, Foy JM: Psychotropic Medications in Primary Care Pediatrics. Textbook of Pediatric Care, 2nd Edition, American Academy of Pediatrics Press, Chapter 62, in press. 57. Towbin KE & Riddle MA: Obsessive-Compulsive Disorder. In: Lewis’s Child and Adolescent Psychiatry: A Comprehensive Textbook, Fifth Edition, A. Martin, et al. eds., Baltimore: Lippincott, Williams & Wilkins, in press.

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V. Books (Edited Volumes) 1. Riddle MA (ed): Pediatric Psychopharmacology I, Child and Adolescent Psychiatric Clinics of North America, Volume 4:1, W.B. Saunders Co., Philadelphia, 1995. 2. Riddle MA (ed): Pediatric Psychopharmacology II, Child and Adolescent Psychiatric Clinics of North America, Volume 4:2, W.B. Saunders Co., Philadelphia, 1995. 3. Luby JL and Riddle MA (eds): Advances in Preschool Psychopharmacology. Mary Ann Liebert, Inc., New Rochelle, New York, 2009. 4. Riddle MA: Pediatric Psychopharmacology for Primary Care. American Academy of Pediatrics, Elk Grove, Illinois, 2015.

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VI. Newsletter/ Articles 1. Reeves G, Riddle MA: Antipsychotic-induced weight gain and metabolic side effects: Underlying mechanisms, monitoring, and pharmacological intervention/prevention strategies. Child and Adolescent Psychopharmacology News 15:1-6, 2010. 2. Gottfried R, Riddle MA: Non-pharmacological treatments for obesity. Child and Adolescent Psychopharmacology News 15:7-9, 2010.

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VII. Book Reviews 1. Riddle MA: The Child at Psychiatric Risk, Ralph E. Tarter (Ed.), Oxford University Press, New York, 1984. 2. Riddle MA, Velosa, JF: Practitioners Guide to Psychoactive Drugs for Children and Adolescents, 2001. 05/10/2016