curriculum vitae july 2017 john l. griffith, phd · curriculum vitae july 2017 john l. griffith,...

CURRICULUM VITAE

July 2017

JOHN L. GRIFFITH, PhD

Bouvé College of Health Sciences Northeastern University

Bouvé College of Health Sciences Northeastern University 360 Huntington Avenue Boston, MA. 02115 Telephone: (617) 373-7516

EDUCATION Boston University, Boston, MA Ph.D. Mathematics 1994 Tufts University, Medford, MA M.S. Mathematics 1982 Claremont Men's College, Claremont, CA. B.A. 1976

ACADEMIC APPOINTMENTS Bouvé College of Health Sciences, Northeastern University 2012 – Present Professor, Department of Health Sciences 2012 – 2017 Professor, Department of Applied Psychology Tufts Sackler Graduate School of Biomedical Sciences 2002 - 2012 Associate Professor of Medicine

Tufts University School of Medicine 2012 - Present Adjunct Associate Professor of Medicine 1999 - 2012 Associate Professor of Medicine 1996 - 2012 Assistant Professor of Family Medicine and Community Health 1993 - 1999 Assistant Professor of Medicine

Tufts University School of Veterinary Medicine 1995 Quantitative Course Director, Animals and Public Policy

Boston University 1982-1990 Lecturer, Department of Mathematics

Tufts University 1980-1982 Lecturer, Department of Mathematics

Curriculum Vitae - John L Griffith ________________________________________________________________________________________________________________________________________________________________________________________________________

PROFESSIONAL ACTIVITIES

Select Hospital and University Appointments

Associate Dean for Research Bouvé College of Health Sciences, Northeastern University, 2012 to 2017

Director, Biostatistics Service Center Bouvé College of Health Sciences, Northeastern University, 2014 to present

Interim co-Director, The Institute on Urban Health Research and Practice (IUHRP) Bouvé College of Health Sciences, Northeastern University, 2014 to 2015

Biostatistics Core, Tufts MC Cancer Center, Director Tufts Medical Center, 2009 to 2012

Human Institutional Review Board Tufts University / Tufts Medical Center, 2000 to 2011

Special and Scientific Staff Tufts Medical Center, 2000 to 2012

Center for Cardiovascular Health Services Research, Senior Statistician Tufts Medical Center, 1988 to 2012

Tufts Clinical and Translational Science Institute, Associate Director Tufts University School of Medicine, 2008 to 2011

The Research Design Center (formerly the Design and Data Resource Center), Director Tufts Medical Center, 2006 to 2008 Tufts Clinical and Translational Science Institute, 2008 to 2011

Clinical Research Portal, co-Director Tufts Clinical and Translational Science Institute, 2008 to 2011

Clinical Research Scientific Review Committee Tufts Medical Center, 2003 to 2008

General Clinical Research Center, Statistical Director Tufts Medical Center, 2001 to 2006

Biostatistics Research Center, Director Tufts Medical Center, 1989 to 2006


Select Faculty Committee Memberships

2015 - 2016 Northeastern University IT Strategic Planning Committee

2013 - Northeastern University Research Computing Advisory Committee

2012 - 2017 Bouvé College of Health Sciences Liaison, Bouvé Research Committee

2011 - 2012 Tufts Sackler School of Biomedical Sciences, CTS program Admissions Committee

2011 - 2012 Tufts Sackler School of Biomedical Sciences, CTS program PhD Qualifying Exam Committee

1999 - 2012 Tufts Sackler School of Biomedical Sciences, CTS Program Faculty Advisory Committee

1999 - 2012 Tufts Medical Center, Fellowship in Clinical Care Research Faculty Advisory Committee

2011 Faculty Recruitment Committee, Department of Health Sciences Northeastern University

2009 - 2010 Tufts University Research IT Steering Committee

2004 - 2010 Institute for Clinical Research and Health Policy Studies Infrastructure Committee, Chair

2003 - 2008 Tufts Medical Center Research Information Services Committee, Chair

1999 - 2001 Tufts University Sackler School of Biomedical Sciences, Clinical Research Program PhD Qualifying Exam Committee

1995 - 2001 New England Medical Center, Fellowship in Clinical Care Research Admissions Committee

Journal Reviewer

Clinical Infectious Disease, Statistical Editor 2003-2006

American Heart Journal

Circulation

Journal of Clinical Pharmacology

Journal of Women’s Health

Medical Decision Making

Statistics in Medicine

Trials


Scientific Review Committees

2016, 2017 Charles A. King Trust Postdoctoral Research Fellowship Program Scientific Review Committee: Clinical/Health Services 2003 - 2006 Scientific Review and Evaluation Board for Health Services Research.

Department of Veterans Affairs.

1995 Medical Treatment Effectiveness Research: Port II Special Emphasis Panel. Agency for Health Care Policy and Research (AHCPR).

1994 Medical Treatment Effectiveness Research: Port II Special Emphasis Panel.

Agency for Health Care Policy and Research (AHCPR

Data Safety Monitoring Boards

2009 - 2011 Data Safety Monitoring Board (DSMB), Member Lactobacillus rhamnosus GG for the Elimination of Vancomycin-Resistant

Enterococcus Colonization. R21AT001892, U01AT001892. PI: D. Snydman. 2010 - 2015 Data Safety Monitoring Board (DSMB), Member

CARE+ Corrections: Technology for Jail HIV/HCV Testing, Linkage, and Care (TLC). R01DA03747. PI: C. Beckwith.

2012 - 2014 Data Safety Monitoring Board (DSMB), Member

U01AT002133, U01AT002388, U01AT002952. PI: P. Hibberd. Open Label Study to Evaluate the Safety of Lactobacillus Rhamnosus GG ATCC

53103 in Elderly Subjects Double Blind Randomized Controlled Trial to Evaluate the Safety of Lactobacillus

Rhamnosus GG ATCC 53103 (LGG) vs. Placebo in Elderly Subjects Receiving Trivalent Inactivated Influenza Vaccine

Double Blind Randomized Controlled Trial to Evaluate the Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) vs. Placebo in Elderly Subjects Receiving Live Attenuated Influenza Vaccine

Selected Workshops and Presentations (since 2011)

“Data Analyses Using SAS” Northeastern University, Biostatistics Service Center, March 2017

“The Simplicity Behind Complexity Workshop Series: A workshop on applied multilevel modeling” Northeastern University, Biostatistics Service Center, November 2016

“Implementing Adaptive Designs in Clinical Research” Northeastern University Center for Self Care & Health, February 2015

“Translating Science to Health Care: the Use of Predictive Models in Decision Making” Department of Quantitative Health Sciences, University of Massachusetts Medical School, February 2014

“Modeling using SAS” Boston Public Health Commission, May 2013


“Research at the Bouvé College of Health Sciences” Bouvé College Honors Program, November 2012

“Exploratory Data Analysis”

Boston Public Health Commission, April 2012

“Analysis of Complex Survey Data in SAS”

Boston Public Health Commission, January 2012

“Why Studies Fail: Bias & Confounding” Lahey Clinic, November 2011

“How Many Subjects do I Need for My Study?” Tufts Medical Center (Infectious Disease), August 2011

“Interactions and Confounding” Boston Public Health Commission, October 2011

“Sample Size and Non-Inferiority Testing” Clinical and Translational Science Program, October 2011

“Pitfalls in Statistical Analyses” St. Elizabeth’s Medical Center (Psychiatry), August 2011

“Exploratory Data Analysis” St. Elizabeth’s Medical Center (Psychiatry), August 2011

“Translational Research” New England Baptist Hospital, Keynote address Research Day, June 2011

“Statistical review & Evaluating Medical Journals” Tufts Medical Center (Radiation Oncology), June 2011

“Analyzing Complex Survey Data in SAS” Boston Public Health Commission, June 2011

“Observational Studies” Cummings School of Veterinary Medicine, June 2011

“Pitfalls in Statistical Analyses” Tufts Medical Center (Radiation Oncology), June 2011

“Steps of an analysis” Lahey Clinic, April 2011

“Regression Analyses” St. Elizabeth’s Medical Center, April 2011

“Pitfalls in Statistical Analysis” St. Elizabeth’s Medical Center, March 2011

“Adaptive Randomization” Tufts Medical Center (Biostatistics Research Center), March 2011

“Exploratory Data Analysis” Lahey Clinic, February 2011

“Measures of Association” Tufts Medical Center, 2011


Workshops at National Meetings “Testing Logistic Regression Predictive Instruments: Different Measures for Different Applications”. HP Selker, JL Griffith, RB D’Agostino. 12th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 4, 1989. “Logistic Regression Predictive Instruments: Different Measures for Different Applications”. HP Selker, JL Griffith, RB D’Agostino. 13th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 3, 1990. “Techniques for Assessing the Performance of Logistic Regression Clinical Predictive Instruments”. HP Selker, JL Griffith, RB D’Agostino. 15th Annual Meeting of the Society of General Internal Medicine, Washington DC. April 30, 1992. “Combining Data from Multiple Clinical Studies for Medical Effectiveness and Clinical Research”. HP Selker, JL Griffith, JR Beshansky, JD Scott. 16th Annual Meeting of the Society of General Internal Medicine, Washington DC. April 29, 1993. “Comparison of Using Logistic Regression, Classification Trees, and Neural Networks for Predicting a Medical Outcome”. JL Griffith, HP Selker. 17th Annual Meeting of the Society of General Internal Medicine, Washington DC. April 28, 1994. “Advanced Construction of Predictive Models for Medical Outcomes”. JL Griffith, HP Selker, C Schmid. 19th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 2, 1996. “Advanced Construction of Predictive Models for Medical Outcomes”. JL Griffith, HP Selker, C Schmid. 20th Annual Meeting of the Society of General Internal Medicine, Washington DC. May 3, 1997. “Advanced Construction of Predictive Models for Medical Outcomes”. HP Selker, JL Griffith. 21st Annual Meeting of the Society of General Internal Medicine, Chicago, April 23, 1998.

International Workshops Statistical Coordinator, "ADDR Workshop on Multivariable Analysis". The Applied Diarrheal Disease Research Project (ADDR). Funded by U.S. Agency for International Development. Islamabad, Pakistan. May 11-18, 1994.


Teaching Experience (since Fall 2013)

Fall 2017 Advanced Methods in Biostatistics (PHTH 6440) Northeastern University Bouvé College Department of Health Sciences

Experimental Design and Biostatistics (PHSC 6214) Northeastern University Bouvé College School of Pharmacy

Spring 2017 Analysis of Messy Data (PHTH 6460) Northeastern University Bouvé College Department of Health Sciences

Experimental Design and Biostatistics (PHSC 6214 online) Northeastern University Bouvé College School of Pharmacy

Fall 2016 Experimental Design and Biostatistics (PHSC 6214) Northeastern University Bouvé College School of Pharmacy

Spring 2016 Experimental Design and Biostatistics (PHSC 6214) Northeastern University Bouvé College School of Pharmacy

Experimental Design and Biostatistics (PHSC 6214 - online) Northeastern University Bouvé College School of Pharmacy

Fall 2015 Advanced Methods in Biostatistics (PHTH6440) Northeastern University Bouvé College Department of Health Sciences



Research Methodology and Biostatistics (PHMD 3450), co-instructor Northeastern University Bouvé College School of Pharmacy

Fall 2014 Advanced Methods in Biostatistics (PHTH6440) Northeastern University Bouvé College Department of Health Sciences



Research Methodology and Biostatistics (PHMD 3450), co-instructor Northeastern University Bouvé College School of Pharmacy

Fall 2013 Experimental Design and Biostatistics (PHSC 6214), co-instructor Northeastern University Bouvé College School of Pharmacy


Selected Research Experience Statistical Consulting (J Griffith)

Agency: Boston Public Health Commission Dates: 2013 - 2017 Role: Consultant

Shared Decision Making and Renal Supportative Care (L. Cohen)

Agency: PCORI Dates: 2013 - 2016 Role: Co-investigator. Director, Data Coordinating Center

The Meaning and Impact of Limited Literacy for People with Serious Mental Illness (A. Lincoln)

Agency: NIMH (R01 MH096707) Date: 2012 - 2015 Role: Biostatistician

Boston Puerto Rican Health Study – CVD Risk Factors (K. Tucker)

Agency: NHLBI (P50 HL 105185) Dates: 2010 - 2015 Role: Site Principal Investigator; Director Statistical Core

The Risk of Paradoxical Embolism (ROPE) Study (D. Kent) Agency: NINDS (R01 NS 062153) Dates: 2009 - 2014 Role: Biostatistician Tufts Clinical and Translational Science Institute (H. Selker) Agency: NCRR (UL1 RR 025752) Dates: 2008 - 2013 Role: Co-Principal Investigator Data Coordinating Center: The IMMEDIATE Trial (R. D’Agostino) Agency: NHLBI (R01 HL 077826) Dates: 2004 - 2010 Role: Co-Principal Investigator

Nutrition, Stress and Bone in Older Puerto Ricans (K. Tucker) Agency: NIA (R01 AG 027087) Dates: 2007 - 2010 Role: co-Investigator / Biostatistician


Publications

1. Pozen MW, D'Agostino RB, Selker HP, Griffith JL. Tables for using a predictive instrument for acute ischemic heart disease. Distributed to physicians.

2. Selker HP, Griffith JL, Dorey FJ, D'Agostino RB. How do physicians adapt when the coronary care unit is full? A prospective multicenter clinical trial. JAMA, 257:1181-85, 1987.

3. Griffith JL, Selker HP, Beshansky JR, MacLeod BG. Cardiac Severity System Software. Prepared with support of the Robert Wood Johnson Foundation, 1989.

4. Selker HP, Griffith JL, D'Agostino RB. A tool for judging coronary care unit admission appropriateness valid for both real-time and retrospective use: A time-insensitive predictive instrument (TIPI) for acute cardiac ischemia: A multicenter study. Med Care, 29:610-627, 1991.

5. Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute myocardial infarction mortality: A multicenter study. Med Care, 29:1196-1211, 1991.

6. Snydman DR, Werner BG, Tilney NL, Kirkman RL, Milford EL, Cho SI, Bush HL, Levey AS, Strom TB, Carpenter CB, Berardi VP, Levey RH, Harmon WE, Zimmerman CE, Katz A, Heinze-Lacey B, Shapiro ME, Steinman T, LoGerfo F, Idelson B, McIver J, Leszczynski J, Griffith JL, Grady GF. Final analysis of primary cytomegalovirus disease prevention in renal transplant recipients with a cytomegalovirus-immune globulin: comparison of the randomized and open-label trials. Transplantation Proceedings, 23:1357-60, 1991.

7. Georgeson S, Linzer M, Griffith JL, Weld L, Selker HP. Acute cardiac ischemia in patients with syncope: Importance of the initial electrocardiogram. J Gen Int Med, 7:379-386, 1992.

8. Selker HP, Griffith JL, Beshansky JR, Califf RM, D'Agostino RB, Laks MM, Lee KL Maynard C, Wagner GS, Weaver WD. The Thrombolytic Predictive Instrument (TPI) Project: Combining clinical study databases to take medical effectiveness research to the streets. AHCPR DHHS, USA,9-31, 1992.

9. Long WJ, Griffith JL, Selker HP, D'Agostino RB. A comparison of logistic regression to decision tree induction in a medical domain. Comput Biomed Res, 26:74-97, 1993.

10. Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rubin RH, Dienstag JL, Rohrer RH, Freeman R, Jenkins R, Lewis D, Hammer S, O'Rourke E, Grady G, Fawaz K, Kaplan MM, Hoffman MA, Katz AT, Doran M. Cytomegalovirus immune prophylaxis in liver transplantation: a randomized, double-blind, placebo-controlled trial. Ann Intern Med, 119:984-991, 1993.

11. George MJ, Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R, Jenkins R, Lewis WD. Use of ganciclovir plus cytomegalovirus immune globulin to treat CMV pneumonia in orthotopic liver transplant recipients. Trans Proc, 25:22-24, 1993.

12. Griffith JL. Maximum likelihood estimates for feed forward multi-layer neural networks. PhD dissertation, Boston University, 1994.

13. Larsen GC, Griffith JL, Beshansky JR, D'Agostino RB, Selker HP. Electrocardiographic left ventricular hypertrophy in patients with suspected acute cardiac ischemia: its influence on diagnosis, triage and short-term prognosis. A multicenter study. J Gen Intern Med, 9:666-673, 1994. [PMID: 7876948]

14. Sarasin FP, Reymond JM, Griffith JL, Beshansky JR, Schifferli JA, Unger PF, Scherrer JR, Selker HP. Impact of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) on the speed of triage decision making for emergency department patients presenting with chest pain: a controlled clinical trial. J Gen Intern Med, 9;187-194, 1994.


15. Selker HP, Beshansky JR, Schmid CS, Griffith JL, Longstreth WT, O'Connor CM, Caplan LR, Massey EW, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD, Califf RM. Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage: thrombolytic predictive instrument (TPI) project results. Circulation, 90:1657-1661, 1994.

16. Selker HP, Griffith JL, D'Agostino RB. A time-insensitive predictive instrument for acute mortality due to congestive heart failure: development, testing, and use for comparing hospitals. A multi-center study. Med Care, 32:1040-1052, 1994.

17. Snydman DR, Werner BG, Dougherty NN, Griffith JL, Rohrer RH, Freeman R, Jenkins R. Lewis WD O'Rourke E, and the Boston Center for Liver Transplantation CMVIG-Study Group. A further analysis of the use of cytomegalovirus immune globulin in orthoptic liver transplant patients at risk for primary infection. Trans Proc, 26:23-27, 1994.

18. Udelson JE, Coleman PS, Metherall J, Pandian NG, Gomez AR, Griffith JL, Shea NL, Oates E, Konstam MA. Predicting recovery of severe regional ventricular dysfunction: comparison of resting scintigraphy with thallium201 and technetium99-sestamibi. Circulation, 89:2552-2561, 1994.

19. Chuttani K, Metherall J, Griffith J, Oates E, Konstam MA, Pauker SG, Salem DM, Udelson JE. Enhanced hepatic uptake of thallium-210 in patients with severe narrowing of the right coronary artery. AM J Cardiol, 76:1020-1024, 1995.

20. Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Wagner GS, Weaver WD. The exclusion of women from clinical trials of thrombolytic therapy: implications for developing the thrombolytic predictive instrument. Med Decis Making,15:38-43, 1995.

21. Selker, HP, Griffith JL, Patil S, Long WL, D'Agostino RB. A comparison of the performance of mathematical predictive methods for medical diagnosis: the emergency department presentation of acute cardiac ischemia. J of Investig Med; 43:468-476, 1995.

22. Snydman DR, Werner BG, Meissner HC, Cheeseman SH, Schwab J, Bednarek F, Kennedy JL, Herschel M, Magno A, Levin MJ, Valaes T, Berkman E, McIver J, Leszczynski J, Griffith JL, Grady GF. Use of cytomegalovirus immune globulin in multiply transfused premature neonates. Pediatr Infect Dis J;14:34-40, 1995.

23. Falagas ME, Snydman DR, George M, Werner B, Ruthazer R, Griffith J, Werner BG, Freeman R, Rohrer R, Freeman R, and the Boston Center for Liver Transplantation CMVIG Study Group. Incidence and predictors of cytomegalovirus pneumonia in orthotopic liver transplant recipients. Transplantation; 61; 1716-1720, 1996.

24. Falagas ME, Snydman DR, Ruthazer R, Griffith J, and the Boston Center for Liver Transplantation CMVIG study group. Primary cytomegalovirus infection in liver transplant recipients: comparison of infections transmitted via donor organs and via transfusions. Clinical Infectious Diseases; 23; 292-297, 1996.

25. Falagas ME, Snydman DR, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG study group. Exposure to cytomegalovirus from the donated organ is a risk factor for bacteremia in orthotopic liver transplant recipients. Clin Infect Diseases; 23;468-74, 1996. [PMID: 8879766]

26. Katz DA, Beshansky JR, Griffith JL, Selker HP. The need to include empiric clinical data in formulating medical practice guidelines. JAMA, 276;1568-74, 1996. [PMID: 8918854]


27. Kimmelstiel CD, Perrone R, Kilcoyne L, Souhrada J, Udleson J, Smith J, de Bold A, Griffith JL, Konstam MA. Effects of renal neutral endopeptidase inhibition on sodium excretion, renal hemodynamics and neurohormonal activation in patients with congestive heart failure. Cardiology, 87:46-53, 1996.

28. Maynard C, Beshansky JR, Griffith JL, Selker HP. The influence of sex on the use of cardiac procedures in patients presenting to the emergency department: A prospective multicenter study. Circulation, 94:93-98, 1996.

29. Midgette AS, Griffith JL, Califf RM, Laks MM, Dietz SB, Beshansky JR, Selker HP. Prediction of the infarct-related artery in acute myocardial infarction by a scoring system using summary ST-segment and T-wave changes. Am J Cardiol, 78:389-395, 1996. [PMID: 8752181]

30. Coronado BE, Griffith JL, Beshansky JR, Selker HP. Hospital mortality in women and men presenting to the emergency department with acute cardiac ischemia: A prospective multicenter study. J Am Coll Cardiol, 29:1490-1496, 1997.

31. D’Agostino RB Sr., Griffith JL, Schmid CH and Terrin NT (1997). Measures for evaluating model performance. Proceedings of the Biometrics Section, American Statistical Association, 1997.

32. Falagas ME, Snydman DR, Griffith J, Ruthazer R, Werner BG, and the Boston Center for Liver Transplantation CMVIG study group. Effect of Cytomegalovirus infection on first-year mortality rates among orthotopic liver transplant recipients. Ann Intern Med, 126:275-279, 1997.

33. Falagas ME, Barefoot L, Griffith J, Ruthazer R, Snydman DR. Risk factors leading to clinical failure in patients with intra-abdominal or skin/soft tissue infections. Eur. J. Clin. Microbiol. Infect. Dis, 15:913-921, 1997.

34. Falagas ME, Snydman DR, Ruthazer R, Werner BG, Griffith JL and the Boston Center for Liver Transplantation CMVIG Study Group. Surveillance cultures of blood, urine, and throat specimens are not valuable for predicting cytomegalovirus disease in liver transplant recipients. Clin Infect Dis, 24:824-829, 1997.

35. Falagas ME, Arbo M, Ruthazer R, Griffith J, Werner BG, Rohrer R, Freeman R, Lewis WD, Snydman DR. Cytomegalovirus disease is associated with increased cost and hospital length of stay among orthotopic liver transplant recipients. Transplantation 63: 1595-1601, 1997.

36. Falagas ME, Snydman DR, Griffith JL, Werner BG, Freemen R, and the Boston Center for Liver Transplantation CMVIG Study Group. Clinical and epidemiological predictors of recurrent cytomegalovirus disease in orthotopic liver transplant patients. Clin Infec Dis 25:314-317, 1997.

37. Falagas ME, Snydman DR, Griffith JL, Ruthazer R, Werner BG, Freemen R, Rohrer R and the Boston Center for Liver Transplantation CMVIG Study Group. Cytomegalovirus immune globulin (CMVIG) is associated with increased survival after orthotopic liver transplantation. Clin Trans 11:432-437, 1997.

38. George M, Snydman DR, Werner BG, Griffith JL, Falages ME, Doughery NN, Rubin R, and the Boston Center for Liver Transplantation CMVIG Study Group. The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients. Amer J Med 103:106-113, 1997.

39. Griffith JL, Schmid CH, Terrin N and D’Agostino RB Sr. Impact of sample size and outcome prevalence on the predictive performance of logistic regression, classification trees and neural networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.


40. Hayes DL, Wang PJ, Reynolds DW, Estes M, Griffith JL, Steffens RA, Carol GL, Findlay GK, Johnson CM. Pacemaker interference form hand-held wireless telephones: results of a multi-center study. NEJM 336:1473-1479, 1997.

41. Link MS, Costeas X, Griffith JL, Colburn CC, Estes M, Wang PJ. High incidence of appropriate implantable cardioverter defibrillator therapy in patients with syncope of unknown etiology. J Am Coll Cardiol, 29:370-375, 1997.

42. Maynard C, Beshansky JR, Griffith JL, Selker HP. Causes of chest pain and symptoms suggestive of acute cardiac ischemia in African American patients presenting to the emergency department: a multicenter study. JNMA, 89:665-671, 1997.

43. Schmid CH, D’Agostino RB, Griffith JL, Beshansky JR, Selker HP. A logistic regression model when some events precede treatment: the effect of thrombolytic therapy for acute myocardial infarction on the risk of cardiac arrest. J Clin Epidemiol, 50:1219-1229, 1997.

44. Schmid CH, Griffith JL, Terrin NT, and D’Agostino RB Sr. Synthesizing the treatment of missing data in logistic regression, classification trees and neural networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.

45. Sege B, Perry C, Stigol L, Cohen L, Cohn L, Griffith J, Cohen M, Spivak H. Short-term effectiveness of anticipatory guidance to reduce early childhood risks for subsequent violence. Arch Pediatr Adolesc Med, 151:392-397, 1997.

46. Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D’Agostino RB, Laks MM, Lee KL, Maynard C, Selvester RH, Wagner GS, Weaver WD. Patient-specific predictions of outcomes in myocardial infarction for real-time emergency use: a thrombolytic predictive instrument. Ann Intern Med, 127: 538-556, 1997

47. Terrin N, Griffith JL, Schmid CH and D’Agostino RB Sr. The impact of outliers and distortions on the predictive performance of logistic regression, classification trees and neural networks. Proceedings of the Biometrics Section, American Statistical Association, 1997.

48. Zucker DR, Griffith JL, Beshansky JR, Selker HP. Presentations of acute myocardial infarction in men and women. JGIM, 12:79-87, 1997.

49. Faith MS, Manibay E, Kravitz M, Griffith J, Allison DB. Relative body weight and self-esteem among African Americans in four nationally representative samples. Obesity Research, 6: 430-437, 1998. [PMID: 9845233]

50. Falagas ME, Walker AM, Jick H, Ruthazer R, Griffith JL, Snydman DR. Late incidence of cancer after metronisaxole use: a matched metronisazole use/nonuser study. Clin Inf. Dis, 26:383-8, 1998. [PMID: 9502459]

51. Falagas ME, Paya C, Ruthazer R, Badley A, Patel R, Wiesner R, Griffith J, Freeman R, Rohrer R, Werner BG, Snydman DR. Significance of Cytomegalovirus for Long-Term Survival after Orthotopic Liver Transplantation: A Prospective Derivation and Validation Cohort Analysis. Transplantation, 66: 1020-1028, 1998. [PMID: 9808486]

52. Kulig J, Valentine J, Griffith JL, Ruthazer R. Predictive model of weapon-carrying among urban high school students. J Adol Health, 22:312-319, 1998. [PMID: 9561463]

53. Picken HA, Zucker DR, Griffith JL, Beshansky JR, Selker HP. Insurance type and the transportation to emergency departments for patients with acute cardiac ischemia: the ACI-TIPI trial insurance study. Amer J Managed Care, 4:821-827, 1998. [PMID: 10181068]


54. Pope JH, Ruthazer R, Beshansky JR, Griffith, JL, Selker HP. Clinical features of emergency department patients presenting with symptoms suggestive of acute cardiac ischemia: A multicenter study. Journal of Thrombosis and Thrombolysis, 6:63-74, 1998. [PMID: 10751787]

55. Selker HP, Beshansky JR, Griffith JL, Aufderheide TP, Ballin DX, Bernard SA, Crespo SG, Feldman J, Fish SS, Gibler WB, Kiez DA, McNutt RA, Moulton AW, Ornato JP, Podried PJ, Salem DN, Sayre MR, Woolard RH. The use of the Acute Cardiac Ischemic Time-Insensitive Predictive Instrument (ACI-TIPI) to assist emergency department triage of patients with chest pain or other symptoms suggestive of acute cardiac ischemia: a multicenter controlled clinical trial. Ann Intern Med, 129:845-855, 1998. [PMID: 9867725]

56. Valentine J, Griffith JL, Ruthazer R, Gottlief B, Keel S. Strengthening causal inference in adolescent drug prevention studies: methods and findings from a controlled study of the urban youth connection program. Drugs & Society, 12:127-145, 1998.

57. Valentine J, Gottlieb B, Keel S, Griffith J, Ruthazer R. Measuring the effectiveness of the urban youth connection: the case for dose-response modeling to demonstrate the impact of an adolescent substance abuse prevention program. J of Adol Res, 1998.

58. Bonis PA, Tong MJ, Blatt LM, Conrad A, Griffith JL. A predictive model for the development of hepatocellular carcinoma, liver failure, or liver transplantation for patients presenting to clinic with chronic hepatitis C. Am J Gastroenterology, 94(6): 1605-1612, 1999. [PMID: 10364032]

59. DesJardin JA, Falagas ME, Ruthazer R, Griffith JL, Wawrose D, Schenkein D, Miller K, Snydman D. Clinical utility of blood cultures drawn from indwelling central venous catheters in hospitalized patients with cancer. Annals Intern Med, 131:641-647, 1999. [PMID: 10577325]

60. Link MS, Cesarz CA, Griffith JL, Estes NA 3rd, Wang PJ. Evaluation of coronary revascularization to prevent tachycardia recurrences in survivors of ventricular fibrillation. Am J Cardiol, 83(6): 960-2, 1999. [PMID: 10190419]

61. Sege R, Stringham P, Short S, Griffith J. Ten years after: examination of adolescent screening questions that predict future violence-related injury. J Adol Health, 24:395-402, 1999. [PMID: 10401967]

62. Burns JP, Mitchell C, Outwater KM, Geller M, Griffith JL, Todres I, Truog RD. End-of-life care in the pediatric intensive care unit after the forgoing of life-sustaining treatment. Critical Care Med, 28(8): 3060-3066, 2000. [PMID: 10966296]

63. Feldman JA, Fish SS, Beshansky JR, Griffith JL, Woolard RH, Selker HP. Acute cardiac ischemia in patients with cocaine-associated complaints: results of a multicenter trial. Ann Emergency Med, 36(5): 469-476, 2000. [PMID: 11054201]

64. Koc Y, Miller K, Schenkein DP, Griffith JL, Ahktar M, DesJardin J, Snydman DS. Varicella zoster virus infections following allogeneic bone marrow transplantation: Frequency, risk factors, and clinical outcome. Biology of Blood and Marrow Transplantation, 6:44-49, 2000. [PMID: 10707998]

65. Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Feldman JA, Beshansky JR, Griffith JL, Selker HP. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med, 342:1163-1170, 2000. [PMID: 10770981]

66. Burns JP, Mitchell C, Griffith JL, Troug RD. End-of-life care in the pediatric intensive care unit attitudes and practices of pediatric clinical care physicians and nurses. Crit Care Med, 29(3): 695-696, 2001. [PMID: 11373439]

67. Moskowitz H, Griffith JL, DiScala C, Sege RD. Serious injuries and deaths of adolescent girls resulting from interpersonal violence: Characteristics and trends from the United States, 1989-1998. Arch Pediatr Adolesc Med, 155:903-908, 2001. [PMID: 11483117]


68. Finlay GA, Joseph B, Rodrigues CR, Griffith JL, White AC. Advanced Presentation of Lung

Cancer in Asian Immigrants: A Case-Control Stud. Chest, 122: 1938-1943, 2002. [PMID: 12475830]

69. Gill CJ, Griffith JL, Jacobson D, Skinner S, Gorbach SL, and Wilson IB. Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of life. JAIDS, 30:485-492, 2002. [PMID: 12154339]

70. Greenfield S, Kaplan SH, Kahn R, Ninomiya J, Griffith JL. Profiling care provided by different groups of physicians: Effects of patient case-mix (Bias) and physician-level clustering on quality assessment results. Ann Intern Med, 136:111-121, 2002. [PMID: 11790062]

71. Kent DM, Hayward RA, Griffith JL,Vijan S, Beshansky JR, Califf M, Selker HP. Independently derived and validated predictive model for selecting patients with myocardial infarction who are likely to benefit from tissue plasminogen activator compared with streptokinase. Am J Med,113: 104-111, 2002. [PMID: 12133748]

72. Kent DM, Griffith J. The Framingham scores overestimated the risk for coronary heart disease in Japanese, Hispanic, and Native American cohorts. ACP J Club. 136(1): 36. 2002. [PMID: 11829577]

73. Meyer EC, Burns JP, Griffith JL, Truog RD. Parental perspectives on end-of-life care in the pediatric intensive care unit. Crit Care Med, 30(1): 226-231, 2002. [PMID: 11902266]

74. Sarnak MJ, Tighuouart H, Manjunath G, MacLeod B, Griffith JL, Salem D, Levey AS. Anemia as a risk factor for cardiovascular disease in the atherosclerosis risk in communities (aric) study. Journal of the American College of Cardiology, 40(1):27-33, 2002. [PMID: 12103252]

75. Selker HP, Beshansky JR, Griffith JL, For the TPI Trial Investigators. Use of the electrocardiograph-based thrombolytic predictive instrument to assist thrombolytic and reperfusion therapy for acute myocardial infarction: a multicenter randomized clinical effectiveness trial. Ann Intern Med, 137:87-95, 2002. [PMID: 12118963]

76. Udelson, JE, Beshansky,JR, Ballin,DS, Feldman, JA, Griffith, JL, Heller, GV, Hendel, RC, Pope, JH, Ruthazer, R, Spiegler, EJ, Woolard, RH, Handler, JH, Selker, HP, Myocardial Perfusion Imaging for Evaluation and Triage of Patients With Suspected Acute Cardiac Ischemia, JAMA, 288(21) 2693-2700, 2002. [PMID: 12460092]

77. Manjunath G, Tighiouart H, Ibrahim H, MacLeod B, Salem DN, Griffith JL, Coresh J, Levey AS, Sarnak MJ. Level of kidney function as a risk factor for atherosclerotic cardiovascular outcomes in the community. J Am Coll Cardiol, 41(1):47-55, 2003. [PMID: 12570944]

78. Manjunath G, Tighiouart H, Coresh J, Macleod B, Salem DN, Griffith JL, Levey AS, Sarnak MJ. Level of kidney function as a risk factor for cardiovascular outcomes in the elderly. Kidney Int. 63(3): 1121-9, 2003. [PMID: 12631096]

79. Selker HP, Raitt MH, Schmid CH, Laks MM, Beshansky JR, Griffith JL, Califf RM, Selvester RH, Maynard C, D'Agostino RB, Weaver WD. Time-dependent predictors of primary cardiac arrest in patients with acute myocardial infarction. Am J Cardiol, 91(3):280-6, 2003. [PMID: 12565083]

80. Terrin N, Schmid CH, Griffith JL, D'Agostino RB, Selker HP. External validity of predictive models: a comparison of logistic regression, classification trees, and neural networks. J Clin Epidemiol, 56(8): 721-9, 2003. [PMID: 12954463]

81. Amin MG, Tighiouart H, Weiner DE, Stark PC, Griffith JL, MacLeod B, Salem DN, Sarnak MJ. Hematocrit and left ventricular mass: the Framingham Heart study. J Am Coll Cardiol, 43(7): 1276-82, 2004. [PMID: 15063442]


82. Coronado BE, Pope JE, Griffith JL, Beshansky JR, and Selker HP. Clinical features, triage, and outcome of patients presenting to the ED with suspected acute coronary syndromes but without pain: A multicenter study. The American Journal of Emergency Medicine, 22:568-574, 2004. [PMID: 15666263]

83. Kapetanopoulos A, Heller GV, Selker HP, Ruthazer R, Beshansky JR, Feldman JA, Griffith JL, Hendel RC, Pope JH, Spiegler EJ, Udelson JE. Acute resting myocardial perfusion imaging in patients with diabetes mellitus: results from the Emergency Room Assessment of Sestamibi for Evaluation of Chest Pain (ERASE Chest Pain) trial, J Nucl Cardiol, 11(5):570-577, 2004. [PMID: 15472642]

84. Kent DM, Vijan S, Hayward RA, Griffith JL, Beshansky JR, Selker HP. Tissue plasminogen activator was cost-effective compared to streptokinase in only selected patients with acute myocardial infarction. J Clin Epi, 57(8): 843-852, 2004. [PMID: 15485737]

85. Milch CE, Edmunson JM, Beshansky JR, Griffith JL, Selker HP. Smoking cessation in primary care: a clinical effectiveness trial of two simple interventions. Preventive Medicine, 38(3): 284-294, 2004. [PMID: 14766110]

86. Pope JH, Ruthazer R, Kontos MC, Beshansky JR, Griffith JL, Selker HP. The Impact of Electrocardiographic Left Ventricular Hypertrophy and Bundle Branch Block on the Triage and Outcome of Emergency Department Patients with a Suspected Acute Coronary Syndrome: A Multicenter Study. Am J of Emergency Med. 22(3):156-63, 2004. [PMID: 15138949]

87. Scott TM, Tucker KL, Bhadelia A, Benjamin B, Patz S, Bhadelia R, Liebson E, Price LL, Griffith J, Rosenberg I, Folstein MF. Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders. Am J Geriatr Psychiatry, 12(6):631-8, 2004. [PMID: 15545331]

88. Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol., 15(5):1307-15, 2004. [PMID: 15100371]

89. Weiner D, Tighiouart H, Stark P, Amin M, MacLeod B, Griffith J, Salem D, Levey A, Sarnak M. Kidney disease as a risk factor for recurrent cardiovascular disease and mortality. Am J Kidney Diseases, 44(2): 198-206, 2004. [PMID: 15264177]

90. Dansinger, ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone Diets for Weight Loss and Heart Disease Risk Reduction: A Randomized Trial. JAMA. 293:43-53, 2005. [PMID: 15632335]

91. Pope JH, Ruthazer R, Kontos MC, Beshansky JB, Griffith JL, Selker HP. The Impact of electrocardiographic left ventricular hypertrophy and bundle branch block on the triage and outcome of ED patients with a suspected acute coronary syndrome: a multicenter study. Am J Emerg Med, 22(3): 156-164, 2005. [PMID: 15138949]

92. Vlagopoulos PT, Tighiouart H, Weiner DE, Griffith JL, Pettitt D, Salem DN, Levey AS, Sarnak MJ. Anemia as a risk factor for cardiovascular disease and all-cause mortality in diabetes: the impact of chronic kidney disease. Journal of the American Society of Nephrology, 16(11):3403-10, 2005. [PMID: 16162813]

93. Weiner DE, Tighiouart H, Vlagopoulos PT, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Effects of anemia and left ventricular hypertrophy on cardiovascular disease in patients with chronic kidney disease. J Am Soc Nephrol. 16:1803-1810, 2005. [PMID: 15857925]


94. Golan Y, Doron S, Griffith J, El Gamal H, Tanios M, Blunt K, Barefoot L, Bloom J, Gamson K, Snydman LK, Hansjosten K, Elnekave E, Nasraway SA, and Snydman DR. The impact of gown-use requirement on hand hygiene compliance. Clinical Infectious Diseases 42:370-376, 2006. [PMID: 16392083]

95. Scott TM, Peter I, Tucker KL, Arsenault L, Bergethon P, Bhadelia R, Buell J, Collins L, Dashe JF, Griffith J, Hibberd P, Leins D, Liu T, Ordovas JM, Patz S, Price LL, Qiu WQ, Sarnak M, Selhub J, Smaldone L, Wagner C, Wang L, Weiner D, Yee J, Rosenberg I, Folstein M. The Nutrition, Aging, and Memory in Elders (NAME) study: design and methods for a study of micronutrients and cognitive function in a homebound elderly population. Int J Geriatr Psychiatry, 21(6):519-28, 2006. [PMID: 16645938]

96. Weiner DE, Tabatabai S, Tighiouart H, Elsayed E, Bansal N, Griffith J, Salem DN, Levey AS, Sarnak MJ. Cardiovascular outcomes and all-cause mortality: exploring the interaction between CKD and cardiovascular disease. Am J Kidney Dis. 48(3): 392-401. 2006. [PMID: 16931212]

97. Trokel M, Griffith J, Waddimba A, Sege R. Variation in the Diagnosis of Child Abuse in Severely Injured Infants. Pediatrics, 117: 722-728, 2006. [PMID: 16510652]

98. Bansal N, Tighiouart H, Weiner D, Griffith J, Vlagopoulos P, Salem D, Levin A, Sarnak MJ. Anemia as a Risk Factor for Kidney Function Decline in Individuals with Heart Failure. The American Journal of Cardiology, 99:1137-1142. 2007. [PMID: 17437743]

99. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Ruthazer R, Beshansky JR, Wong JB, Aversano T, and Selker HP. A Geospatial Analysis of Emergency Transport and Inter-Hospital Transfer in ST-Segment Elevation Myocardial Infarction. The American Journal of Cardiology. 101(1):69-74. 2007. [PMID: 18157968]

100. Elsayed EF, Tighiouart H, Griffith J, Kurth T, Levey AS, Salem D, Sarnak MJ, Weiner DE. Cardiovascular disease and subsequent kidney disease, Arch Intern Med. 167(11):1130-6, 2007. [PMID: 17576295]

101. Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Grines CL, Aversano T, Concannon TW, Zalenski RJ, Selker HP. Comparison of Mortality Benefit of Immediate Thrombolytic Therapy Versus Delayed Primary Angioplasty for Acute Myocardial Infarction. The American Journal of Cardiology, 99:1384-1388, 2007. [PMID: 17576295]

102. Pereira AA, Weiner DE, Scott T, Chandra P, Bluestein R, Griffith JL, Sarnak MJ. Subcortical Cognitive Impairment in Dialysis Patients. Hemodialysis International, 11:309-314, 2007. [PMID: 17576295]

103. Vega-Lopez S, Ausman LM, Griffith JL, and Lichtenstein AH. Interindividual Variability and Intra-Individual Reproducibility of Glycemic Index Values for Commercial White Bread. Diabetes Care, 30:1412-1417, 2007. [PMID: 17384339]

104. Weiner DE, Tighiouart H, Levey AS, Elsayed E, Griffith JL, Salem DN, and Sarnak MJ. Lowest Systolic Blood Pressure Is Associated with Stroke in Stages 3 to 4 Chronic Kidney Disease. J. Am. Soc. Nephrol., 18: 960 – 966, 2007. [PMID: 17301190]

105. Weiner DE, Tighiouart H, Griffith JL, Elsayed E, Levey AS, Salem DN, Sarnak MJ. Kidney Disease, Framingham Risk Scores, and Cardiac and Mortality Outcomes. The American Journal of Medicine (120): 552e.1-8. 2007.[ PMID: 17576295]

106. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The Framingham Predictive Instrument in Chronic Kidney Disease. Journal of the American College of Cardiology, 50:217-224. 2007.[ PMID: 17631213]


107. Elsayed EF, Tighiouart H, Weiner DE, Griffith J, Salem D, Levey AS, Sarnak MJ. Waist-to-hip ratio and body mass index as risk factors for cardiovascular events in CKD. Am J Kidney Dis, 52(1): 49-57. [PMID: 18514990]

108. Elsayed EF, Sarnak MJ, Tighiouart H, Griffith JL, Kurth T, Salem DN, Levey AS, Weiner DE. Waist-to-Hip Ratio, Body Mass Index, and Subsequent Kidney Disease and Death. American Journal of Kidney Diseases, 52(1): 29-38. 2008. [PMID: 18511168]

109. Flaherty EG, Sege RD, Griffith J, Price LL, Wasserman R, Slora E, Dhepyasuwan N, Harris D, Norton D, Angelilli ML, Abney D, Binns HJ. From suspicion of physical child abuse to reporting: primary care clinician decision-making. Pediatrics, 122(3):611-9: 2008. [PMID: 18676507]

110. Kent DM, Ruthazer R, Griffith JL, Beshansky JR, Concannon TW, Aversano T, Grines CL, Zalenski RJ, Selker HP. A Percutaneous Coronary Intervention–Thrombolytic Predictive Instrument to Assist Choosing Between Immediate Thrombolytic Therapy Versus Delayed Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction. The American Journal of Cardiology. 101(6): 790-795. 2008. [PMID: 18328842]

111. Layne JE, Sampson SE, Mallio CJ, Hibberd PL, Griffith JL, Das SK, Flanagan WJ, Castaneda-Sceppa C. Successful dissemination of a community-based strength training program for older adults by peer and professional leaders: the people exercising program. J Am Geriatrics Soc, 56(12):2323-9, 2008. [PMID: 19112654]

112. Madan J, Fiascone J, Balasubramanian V, Griffith J, Hagadorn JI. Predictors of Ductal Closure and Intestinal Complications in Very Low Birth Weight Infants Treated with Indomethacin. Neonatology, 94:45-51. 2008. [PMID: 18215699]

113. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Saleem DN, and Levey AS. Uric Acid and Incident Kidney Disease in the Community. J Am Soc Nephrol. 19(6):1204-11. 2008. [PMID: 18337481]

114. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. The Relationship Between Nontraditional Risk Factors and Outcomes in Individuals With Stage 3 to 4 CKD. American Journal of Kidney Diseases. 51(2): 212-223. 2008. [PMID: 18215699]

115. Weiner DE, Tighiouart H, Elsayed EF, Griffith JL, Salem DN, Levey AS, Sarnak MJ. Inflammation and cardiovascular events in individuals with and without chronic kidney disease. Kidney Int. 73(12): 1406-12. 2008. [PMID: 18401337]

116. Castaldi PJ, DeMeo DL, Kent DM, Campbell EJ, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino G, Sandhaus RA, Griffith JL, Silverman EK. Development of predictive models for airflow obstruction in alpha-1-antitrypsin deficiency. Am J Epidemiol. 170(8):1005-13. 2009 [PMID: 19726494].

117. Concannon TW, Griffith JL, Kent DM, Normand SL, Newhouse JP, Atkins J, and Beshansky JR, Selker HP. Elapsed time in emergency medical services for patients with cardiac complaints: are some patients at greater risk for delay? Circ Cardiovasc Qual Outcomes. 2(1):9-15. 2009 [PMID: 20031807]

118. Gabbay E, Meyer KB, Griffith JL, Richardson MM, Miskulin DC. Temporal trends in health-related quality of life among hemodialysis patients in the United States. Clin J Am Soc Nephrol. 5(2):261-7. 2009 [PMID: 20019114].

119. Kaplan SH, Griffith JL, Price LL, Pawlson LG, Greenfield S. Improving the Reliability of Physician Performance Assessment: Identifying the "Physician Effect" on Quality and Creating Composite Measures. Med Care. 47(4):378-87. 2009. [PMID: 19279511]


120. Weiner DE, Bartolomei K, Scott TM, Price L, Griffith JL, Rosenberg I, Levey AS, Folstein MF, Sarnak MJ. Albuminuria, Cognitive Functioning, and White Matter Hyperintensities in Homebound Elders. American Journal of Kidney Diseases. 53(3): 438-447. 2009. [PMID: 19070412]

121. Agganis BT, Weiner DE, Giang LM, Scott T, Tighiouart H, Griffith JL, Sarnak MJ. Depression and Cognitive Function in Maintenance Hemodialysis Patients. Am J Kidney Dis. 56(4):704-12. 2010. [PMID 20673602]

122. Concannon TW, Kent DM, Normand SL, Newhouse JP, Griffith JL, Cohen J, Beshansky JR, Wong JB, Aversano T, Selker HP. Comparative effectiveness of ST-segment-elevation myocardial infarction regionalization strategies. Circ Cardiovasc Qual Outcomes. 3(5):506-13. 2010. [PMID: 20664025]

123. Selker HP, Leslie LK, Wasser JS, Plaut AG, Wilson IB, Griffith JL. Comparative Effectiveness Research as a Conceptual Framework for a Focus on Impact. Clin Transl Sci. 3(2):56-8. 2010. [PMID: 20443959]

124. Tucker KL, Mattei J, Noel SE, Collado BM, Mendez J, Nelson J, Griffith J, Ordovas JM, Falcon LM. The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities. BMC Public Health. 10(107): 2010 [PMID: 2848197]

125. McAlindon TE, Nuite M, Krishnan N, Ruthazer R, Price LL, Burstein D, Griffith J, Flechsenhar K. Change In Knee Osteoarthritis Cartilage Detected By Delayed Gadolinium Enhanced Magnetic Resonance Imaging Following Treatment With Collagen Hydrolysate: A Pilot Randomized Controlled Trial. Osteoarthritis Cartilage. 19(4):399-405. 2011. [PMID: 21251991]

126. Selker HP, Beshansky JR, Ruthazer R, Sheehan PR, Sayah AJ, Atkins JM, Aufderheide TP, Pirrallo RG, D'Agostino RB, Massaro JM, Griffith JL. Emergency medical service predictive instrument-aided diagnosis and treatment of acute coronary syndromes and ST-segment elevation myocardial infarction in the IMMEDIATE trial. Prehosp Emerg Care. 15(2):139-48. 2011. [PMC41016]

127. Selker HP, Ruthazer R, Terrin N, Griffith JL, Concannon T, Kent DM. Random treatment assignment using mathematical equipoise for comparative effectiveness trials. Clin Transl Sci. 4(1):10-6. 2011. [PMID: 2134895]

128. Tangri N, Wagner M, Griffith J, Miskulin D, Hodsman A, Ansell D, Naimark D. Effect of Bone Mineral Guideline Target Achievement on Mortality in Incident Dialysis Patients: An Analysis of the United Kingdom Renal Registry. Am J Kidney Dis. 57(3):415-21. 2011. [PMCID: 21131115]

129. Wagner M, Ansell D, Kent DM, Griffith JL, Naimark D, Wanner C, Tangri N. Predicting mortality in incident dialysis patients: an analysis of the United Kingdom Renal Registry. Am J Kidney Dis. 57(6):894-902.2011. [PMC3100445]

130. Concannon TW, Nelson J, Goetz J, Griffith JL. A percutaneous coronary intervention lab in every hospital? Circ Cardiovasc Qual Outcomes.5(1):14-20. 2012. [PMC4440579]

131. Moorthy D, Peter I, Scott TM, Parnell LD, Lai CQ, Crott JW, Ordovás JM, Selhub J, Griffith J, Rosenberg IH, Tucker KL, Troen AM. Status of vitamins B-12 and B-6 but not of folate, homocysteine, and the methylenetetrahydrofolate reductase C677T polymorphism are associated with impaired cognition and depression in adults. J Nutr. 142(8). 2012. [PMC3397340]

http://www.sciencedirect.com.ezproxy.library.tufts.edu/science?_ob=ArticleURL&_udi=B6W9N-4V4KCD5-1&_user=201547&_coverDate=03%2F31%2F2009&_alid=881021419&_rdoc=3&_fmt=high&_orig=search&_cdi=6687&_sort=d&_st=4&_docanchor=&_ct=104&_acct=C000014058&_version=1&_urlVersion=0&_userid=201547&md5=149d99c0cfd196de023c8bba1fccb76a

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132. Selker HP, Beshansky JR, Sheehan PR, Massaro JM, Griffith JL, D'Agostino RB, Ruthazer R, Atkins JM, Sayah AJ, Levy MK, Richards ME, Aufderheide TP, Braude DA, Pirrallo RG, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Opie LH, Rackley CE, Apstein CS, Udelson JE. Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled trial. JAMA. 307(18):1925-33. 2012. [PMC4167391]

133. Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Massaro JM, Udelson JE, Rashba EJ, Ruthazer R, Sheehan PR, Desvigne-Nickens P, Rosenberg YD, Atkins JM, Sayah AJ, Aufderheide TP, Rackley CE, Opie LH, Lambrew CT, Cobb LA, Macleod BA, Ingwall JS, Zalenski RJ, Apstein CS. Study design for the Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care (IMMEDIATE) Trial: A double-blind randomized controlled trial of intravenous glucose, insulin, and potassium for acute coronary syndromes in emergency medical services. Am Heart J. 163(3):315-22. 2012. [PMC4009621]

134. Thaler DE, Di Angelantonio E, Di Tullio MR, Donovan JS, Griffith J, Homma S, Jaigobin C, Mas JL, Mattle H, Michel P, Mono ML, Nedeltchev K, Papetti F, Ruthazer R, Serena J, Weimar C, Elkind MS, Kent DM. The Risk of Paradoxical Embolism (RoPE) Study: Initial Description of the Completed Database. Int J Stroke. 2012. [PMC400865]

135. Concannon TW, Nelson J, Kent DM, Griffith JL. Evidence of Systematic Duplication by New Percutaneous Coronary Intervention Programs. Circ Cardiovasec Qual Outcomes. 2013. [PMC44369667]

136. Jamal-Allial A, Griffith JL, Tucker KL. The longitudinal association of vitamin D serum concentrations & adiposity phenotype. J Steroid Biochem Mol Biol. 2013. [PMC4055547]

137. Selker HP, Udelson JE, Massaro JM, Ruthazer R, D'Agostino RB, Griffith JL, Sheehan PR, Desvigne-Nickens P, Rosenberg Y, Tian X, Vickery EM, Atkins JM, Aufderheide TP, Sayah AJ, Pirrallo RG, Levy MK, Richards ME, Braude DA, Doyle DD, Frascone RJ, Kosiak DJ, Leaming JM, Van Gelder CM, Walter GP, Wayne MA, Woolard RH, Beshansky JR. One-year outcomes of out-of-hospital administration of intravenous glucose, insulin, and potassium (GIK) in patients with suspected acute coronary syndromes (from the IMMEDIATE [Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency Care] Trial). Am J Cardiol. 2014 15;113(10):1599-605. [PMC4043184]

138. Barr JT, Conlley M, Sluboski K, Griffith J. Beliefs about Medicines in an Urban Community Health Center Hypertension Population. Value Health. 18(7):A397, 2015. [doi.org/10.1016/j.jval.2015.09.901].

139. Eneanya ND, Goff SL, Martinez T, Gutierrez N, Klingensmith J, Griffith JL, Garvey C, Kitsen J, Germain MJ, Marr L, Berzoff J, Unruh M, Cohen LM. Shared decision-making in end-stage renal disease: a protocol for a multi-center study of a communication intervention to improve end-of-life care for dialysis patients. BMC Palliat Care.12;14:30. 2015. [PMC4464129}.

140. Schroy PC, Wong JB, O’Brien MJ, Chen CA, Griffith JL. A Risk Prediction Index for Advanced Colorectal Neoplasia at Screening Colonoscopy. Am J Gastroenterol. 2015. [PMC4705553].

141. Lincoln AK, Adams W, Eyllon M, Garverich S, Prener CG, Griffith JL, Paasche-Orlow MK, Hopper K. The Double Stigma of Limited Literacy and Mental Illness: Examining Barriers to Recovery and Participation among Public Mental Health Service Users. Society and Mental Health. 2017.


Book Chapters

Selker HP, Griffith JL, Beshansky JR. Acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI): A decision aid for emergency department triage and a measure of appropriateness of coronary care unit use. Acute Coronary Care in the Thrombolytic Era, 2nd Edition, Chapter 17. Califf RM, Mark DB, Wagner GS, Editors, St. Louis, Mosby-Year Book, 201-211, 1995.

Schmid CH, Griffith JL. Multivariate classification rules, calibration and discrimination. Encyclopedia of Biostatistics. Armitage P, Colton T, Editors, John Wiley & Sons, 1998.

Abstracts \ Selected Presentations:

Jayes RJ, Larsen GC, Beshansky JR, Griffith JL, D'Agostino RB, Selker HP. How often do emergency room physicians misread ST segments and does it affect patient care? A multicenter study. Presented at the Twelfth Annual Meeting of the Society for General Internal Medicine, Washington DC, April 1989.

Larsen GC, Griffith JL, Beshansky JR, D'Agostino RB,Selker HP. How well do physicians diagnose and manage acute cardiac ischemia in emergency room patients with electrocardiographic left ventricular hypertrophy? A multicenter study. Presented at the Annual Meeting of the American Federation of Clinical Research, Washington DC, April 1989.

Selker HP, Griffith JL, Beshansky JR, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD. The Thrombolytic Predictive Instrument (TPI) Project: Combining clinical study databases to take medical effectiveness research to the streets. Presented at the Agency for Health Care Policy and Research Conference, Minneapolis, Minnesota, September 1991.

Chuttani K, Metherall J, Griffith JL, Oates E, Konstam MA, Pauker SG, Oates E, Coleman P, Salem DN, Konstam MA, Udelson JE. Hepatic uptake of thallium-201 in patients with right coronary artery disease. Presented at the American Heart Association Annual Meeting, 1992.

Griffith JL, D'Agostino RB, Selker HP. Statistical regression techniques for the construction, interpretation, and testing of computer neural networks. Presented at the Annual Meeting of the Society for Medical Decision Making, 1992.

Patil S, Griffith JL, Selker HP. Logistic regression and neural networks as clinical predictive instruments: does one produce a best model? Presented at the Annual Meeting of the Americal Federation of Clinical Research, Clin Res, Baltimore, Maryland, 40:347A, May 1992.

Sarasin FP, Reymond JM, Griffith JL, Beshansky JR, Schifferli JA, Unger PF, Scherrer JR, Selker HP. Impact of the time-insensitive predictive instrument (TIPI) for acute cardiac ischemia (ACI) on emergency department (ED) treatment speed for chest pain patients. Presented at the Annual Meeting of the American Federation for Clinical Research, Baltimore, Maryland, May 1992.

Selker HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD. A thrombolytic predictive instrument for acute myocardial infarction. Presented at the 65th Scientific Session of the American Heart Association, New Orleans, Louisiana, November, 1992.

Selker HP, Schmid CH, Beshansky JR, Griffith JL, Longstreth WT, O'Connor CM, Caplan LR, Massey EW, D'Agostino RB, Laks MM, Lee KL, Wagner GS, TPI Investigators. Pulse pressure predicts thrombolysis-related hemorrhagic stroke. Presented at the 65th Scientific Session of the American Heart Association, New Orleans, Louisiana, November, 1992.


Griffith JL, Selker HP, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Wagner GS, Weaver WD. The thrombolytic predictive instrument (TPI) predictions of thrombolytic therapy impact on 30-day and 1-year mortality for real-time use. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington DC, May 1993.Clin Res, 41: 182A, 1993

Griffith JL, Selker HP. The impact on the area under the receiver-operating characteristic curve of disease prevalence and the distribution of patient characteristics. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington DC, May 1993. Clin Res, 41:181A, 1993.

Maynard C, Selker HP, Beshansky JR, Griffith JL, Schmid CS, Califf RB, D'Agostino RB, Laks MM, Lee KL, Wagner GS, Weaver WD. The influence of gender of patient inclusion in developing the thrombolytic predictive instrument. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington DC, May 1993. Clin Res, 41:201A, 1993.

Midgette AS, Griffith JL, Califf RB, Dietz SB, Selker HP. A summary scoring system using ECG ST segment and T wave changes to predict the infarct related artery in acute myocardial infarction. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington DC, May 1993. Clin Res, 41:217A, 1993.

Schmid CH, Selker HP, Beshansky JR, Griffith JL, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD. A logistic regression model for the effect of thrombolytic therapy on the risk of cardiac arrest when some outcomes precede treatment. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington, DC, April 1993.

Selker, HP, Griffith JL, Beshansky JR, Schmid CH, Califf RM, D'Agostino RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD. A thrombolytic predictive instrument for emergency AMI treatment. Presented at the American College of Cardiology 42nd Scientific Session, Anaheim, California, March 1993.

Snydman DR, Griffith JL, Kahan F. Risk Factors for third generation cephalosporin (C3) and Imipenem (IMP) resistant inducible enterobacteriaceae (IE) and Pseudomonas aeruginosa (PA) among intensive care unit patients (ICU). Presented at the 18th International Congress of Chemotherapy,1993.

Schmid CS, Selker HP, Beshansky JR, Griffith JL, D'Agostino RB, Raitt MH, Califf RB, Laks MM, Lee KL, Maynard C, Wagner GS, Weaver WD. A logistic regression model for the effect of thrombolytic therapy on the risk of cardiac arrest when some outcomes precede treatment. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington DC, May 1994. Clin Res, 41:291A, 1994.

Ahmid A, Griffith JL, Foote C, Rastegar H, Estes M, Wang PJ. Tachycardia cycle length as an independent predictor of cardiac and total mortality in patients with implantable defibrillators. Presented at the 68th Scientific Session of the American Heart Association, Anaheim, California, November 1995.

Coronado BE, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group, Division of Clinical Care Research, New England Medical Center, Boston, MA. Acute Hospital mortality in women and men with acute cardiac ischemia: A prospective multicenter study. Presented at the Annual Meeting of the American Federation for Clinical Research, San Diego, May 1995. Clin Res 43:391A, 1995.

Coronado BE, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. Acute hospital mortality in women and men with acute cardiac ischemia: A prospective multicenter study.


Presented at the Annual Meeting of the American Federation of Clinical Research, San Diego, California, October, 1995. J Invest Med, 43:391A.

Coronado BE, Griffith JL, Beshansky JR, Selker HP, for the ACI-TIPI Investigators. Pain in diabetic patients with acute myocardial infarction: A prospective multicenter study. Presented at the Annual Eastern Region American Federation of Clinical Research Meeting, Boston, October 1995. J Invest Med, 43:503A.

Falagas ME, Snydman DR, Griffith J, Werner BG, Freeman R, Rohrer R, and the Boston Center for Liver Transplantation CMVIG study group. Predictors of recurrent cytomegalovirus disease in orthotopic liver transplant recipients. Presented at the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, California, September 1995.

Falagas ME, Snydman DR, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG study group. Cytomegalovirus exposure from the donated organ is a risk factor for bacteremia in orthotopic liver transplant recipients. Presented at the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), San Francisco, California, September 1995.

Griffith JL, Beshansky JR, Selker HP, for TIPI Working Group, CCHSR, New England Medical Center, Boston, MA. A multicenter prospective test of electrocardiograph-generated ACI-TIPI predictions for acute cardiac ischemia. Presented at the Annual Meeting of the American Federation for Clinical Research, San Diego, May 1995. Clin Res 43:215A.

Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. A multicenter prospective validation of computerized electrocardiograph-generated ACI-TIPI risk groups for acute cardiac ischemia. Presented at the Annual Eastern Region American Federation of Clinical Research Meeting, Boston, October, 1995. J Invest Med, 43:507A.

Maynard C, Beshansky JR, Griffith JL, Selker HP. The influence of gender on the use of cardiac procedures in patients presenting to the emergency department: A multicenter study. Presented at the 68th Scientific Session of the American Heart Association, Anaheim, California, November 1995. Circulation, 92:I-437.

Selker HP, Beshansky JR, Griffith JL for the TIPI Working Group. A controlled trial of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) electrocardiograph on emergency department (ED) triage. Presented at the Annual Eastern Region American Federation of Clinical Research Meeting, Boston, October 1995. J Invest Med, 43:497A.

Zucker DR, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group Division of Clinical Care Research Department of Medicine, New England Medical Center, Boston, MA. Accuracy of Emergency Department diagnosis of acute myocardial infarction in women vs. men: A prospective multicenter study. Presented at the Annual Meeting of the American Federation for Clinical Research, San Diego, May 1995. Clin Res 43:404A.

Zucker DR, Griffith JL, Beshansky JR, Selker HP for the TIPI Working Group. Accuracy of emergency department diagnosis of acute myocardial infarction in women vs. men: A prospective multicenter study. Presented at the American Federation of Clinical Research Meeting, San Diego, California, October 1995. J Invest Med, 43:404A.

Vannan M, Kettle A,Coakely A, Griffith JL, Udelson JE. Influence of infarct zone viability on left ventricular remodeling in the year following first anterior myocardial infarction. Presented at the 68th Scientific Session of the American Heart Association, Anaheim, California, November 1995.

Falagas ME, Barefoot L, Griffith J, Ruthazer R, Snydman DR. Risk factors for clinical failure of antibiotic therapy in patients with intra-abdominal or skin/soft tissue infections treated with cefotetan, cefoxitin, or ampicillin/sulbactam monotherapy: A retrospective controlled study. Presented at the 1st European Congress of Chemotherapy, Glasgow, Scotland, May 1996.


Magno AC, Zucker DR, Griffith JL, Selker HP. Analysis of outcomes in 30 to 34 week gestation (moderate risk) infants: implications for regionalized perinatal programs. Presented at the American Federation for Clinical Research, Washington D.C., May 1996

Picken HA, Zucker DR, Griffith JL, Beshansky JR, Selker HP. Insurance type and the transportation to emergency department (EDs) of patients with chest pain or other symptoms suggestive of acute cardiac ischemia (ACI): the ACI-TIPI insurance study. Presented at the Annual Meeting of the American Federation for Clinical Research, Washington D.C., May 1996

Cory DA, Schmid CH, Griffith JL, Long WJ, D’Agostino RB, Selker HP. How much do we gain from complex logistic regression models? Presented at the 156th Annual Meeting of the American Statistical Association, Chicago, August 1996.

Griffith JL, Schmid CH, Cory DA, Long WJ, D’Agostino RB, Selker HP. Building local binary predictive models that fit globally. Presented at the 156th Annual Meeting of the American Statistical Association, Chicago, August 1996.

Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG Study Group. Primary cytomegalovirus infection in liver transplantation: comparison between donor and transfusion transmitted infection. Presented at the 36th Interscience Conference on Anitmicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana, September 1996.

Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG Study Group. Lack of value of surveillance blood, urine, and throat cytomegalovirus cultures in predicting cytomegalovirus disease in liver transplant recipients. Presented at the 36th Interscience Conference on Anitmicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana, September 1996.

Falagas ME, Snydman DR, Ruthazer R, Griffith J, Werner BG, and the Boston Center for Liver Transplantation CMVIG Study Group. Cancer incidence after metronidazole use: a matched metronidazole user/non-user study of 60,054 subjects. Presented at the 36th Interscience Conference on Anitmicrobial Agents and Chemotherapy (ICAAC), New Orleans, Louisiana, September 1996.

Feldman JA, Fish SS, Beshansky JR, Griffith JL, Woolard RH, Selker HP. Acute cardiac ischemia in patients with cocaine related complaints: results of a large multicenter trial. Presented at the Eastern Regional Meeting of the American Federation for Medical Research, Boston, September 1996.

Feldman JA, Fish SS, Beshansky JR, Griffith JL, McAfee A, Woolard RH, Selker HP. The accuracy of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) in patients with cocaine related complaints: results of the ACI-TIPI clinical trial. Presented at the Eastern Regional Meeting of the American Federation for Medical Research, Boston, September 1996.

Shamsuddin, Rasmussen ZA, Shaheen, Griffith J. Respiratory rates and oxyhaemoglobin saturation in normal children in Gilgit, Northern Areas. Presented in Karachi, September 1996.

Valentine J, Griffith JL, Ruthazer R, Kulig J. A predictive model of weapon-carrying among urban high school students. Presented at the Eastern Regional Meeting of the American Federation for Medical Research, Boston, September 1996.

Woolard RH, Sidman RD, Moulton AW, Connolly E, Griffith JL, Beshansky JR, Selker HP. Creatine kinase testing in the emergency department was associated with an increase in admissions of


chest pain patients who did not have acute ischemia. Presented at the Eastern Regional Meeting of the American Federation for Medical Research, Boston, September 1996.

Griffith JL. The Impact of Sample Size and Outcome Prevalence on the Predictive Performance of Logistic Regression, Classification Trees, and Neural Networks. Presented at the 157th Annual Meeting of the American Statistical Association, Anaheim, August 1997.

Burns J, Outwater K, Geller M, Griffith J, Todres D, Truog R. Ventilator withdrawal at the end-of-life. Presented at the Annual Meeting of Pediatrics, November 1997.

Balk EM, Griffith JL, Beshansky JR, Selker HP. Vomiting as a predictor of acute myocardial infarction in the emergency department. Presented at the Annual Meeting of the Society for General Internal Medicine, April 1998.

Pope JH, Aufderheide TP, Ruthazer R, Woolard RH, Beshansky JR, Griffith JL, Selker HP. Missed diagnoses of acute myocardial infarction in the emergency department: Results from a multicenter study. Presented at the Annual Meeting of the Society for General Internal Medicine, April 1998.

Griffith JL, Ruthazer R, Schmid C, Terrin N. A comparison of regression models, classification trees, and neural networks for the prediction of cardiac complications. Presented at the 158th Annual Meeting of the American Statistical Association, Dallas, August 1998.

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