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CURRICULUM VITAE Mohammed Mohsin A. Safhi, Ph.D.

Dean, Faculty of Pharmacy

Personal

Information

Marital Status:

Married

Nationality: Saudi

Date of birth April 09, 1975

Phone Home +966-73217668

Mobile +966-567795950

E-mail msafhi@jazanu.edu.sa

Education October 2004 -

July 1, 2008

Ph.D. in Molecular Pharmacology, Institute of

Biomedical and Life Science, University of Glasgow,

UK

Work

Experience

1998-2000 Teaching Assistance, in College of Health Science,

Jazan, Saudi Arabia.

2002-2003 Lecturer of Medical Biochemistry, College of Health

Science, Jazan Saudi Arabia.

2002-2003

Manager of Training, in College of Health Science,

Jazan, Saudi Arabia.

July-2008 Assistance Professor of Molecular Pharmacology,

Faculty of Applied Medical Science, Jazan University,

Jazan, Saudi Arabia.

October 2008

Supervisor of academic purpose, Faculty of Applied

Medical Science, Jazan University, Jazan Saudi Arabia.

March 2009

Supervisor of scholarship Department, Jazan

University, Jazan, Saudi Arabia.

September

2009

Dean, Faculty of Pharmacy, Jazan University, Jazan,

Saudi Arabia.

Professional

Qualifications

2006 Selected for oral communication in the conference of

Bioscience 2006, Bioscience for the 21st Century,

SECC, Glasgow, UK, 23-27 July 2006.

2006 Selected for Promega UK Young Biochemist 2006

Competition (as one of best 6 researchers out of 600).

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2007

Selected for oral communication in the conference of

Bioscience 2007, Bioscience SECC, Glasgow, UK, 8-12

July 2007

January 19-21,

2009

Workshops of the First International Saudi Conference

for Health Education and Training Riyadh, Saudi

Arabia

April 20-22,

2009

Workshop on "Molecular Biology Techniques:

Principles and Applications" Abha, Saudi Arabia

May 13-16,

2009

Workshop on Working Toward Program

Accreditation. Jazan University, Saudi Arabia.

26-4-2010 Workshops on the Pharmacy Curriculum

28-7-2009- 8-

8-2009

Training Program for E Learning and Distance Learning,

Japan

August 9-15,

2011

Teaching in Higher Education, Dubai, UAE.

Affiliation 2005-2008 Member of Biomedical Society

2009-till date Member of university time tables committee

2009-till date Permanent member of the committee for scholarships

and training

2009-till date Member of the university consulting committee

2009-till date Member of university senate

2009-till date Member of the national deans of pharmacy colleges

association

2010- till date Permanent member of the committee for educational

affairs

2009-2010 Member of the committee for planning and curriculum

development

2011- till date Member of Drug Abuse Center

2011-till date Member of the forensic medicine committee for Aseer

region

2011-2012

Member of Biomedical Society

2009-2012 Member of Saudi Pharmaceutical Society

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CURRENT FINANCIAL SUPPORT:

No. DETAILS

1. Title

Role in Project

Awarding body

Study the action of KHAT on the brain lipids

Principal Investigator

Substance Abuse Research Center, Jazan University, KSA

2009-2011 Member of American Society for Pharmacology and

Experimental Therapeutics

Conferences

July 17-21,

2005

Bioscience 2005, From Genes to Systems, SECC,

Glasgow, UK.

May 24-28,

2006 8

th International Symposium on Adenosine and

Adenosine Nucleotides, Ferrara, Italy.

July 23-27,

2006

Bioscience 2006, Bioscience for the 21st Century,

SECC, Glasgow, UK.

July 8-12,

2007

Bioscience 2007, SECC, Glasgow, UK.

July 8, 2007 Life Science, The Young Life Scientists Symposium,

University of Strathclyde, Glasgow, UK.

January 19-21,

2009

The First International Saudi Conference for Health

Education and Training Riyadh, Saudi Arabia.

April 26-28,

2010 The 8

th Saudi International Pharmaceutical

Conference and Exhibition Riyadh, Saudi Arabia

June 27-29,

2011

Advances in the cellular and molecular biology of

angiogenesis.

February 27th

2013

3rd

Medical Research Day, Organized by Faculty of

Medicine, Jazan University

10th

Feb 2015

One day Seminar on “National Workshop on Khat

Biomedical Research” Organized by Substance Abuse

Research Centre (SARC), Jazan University, Gizan

15-17 Feb2015 Three days International Conference on “Clinical

Pharmacy”, Organized by College of Pharmacy, Al-

Qassim University, Qassim, Saudi Arabia.

Awards &

Achievements

March 2014

Accredited and recognized by the International

Accreditation Organization (IAO), U.S.A

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Award period

Funding Amount

September 1, 2011-June 30, 2011

SAR 160,000

2. Title

Role in Project

Awarding body

Award period

Funding Amount

Action of khat on neurotransmitters

Co-Investigator

Substance Abuse Research Center, Jazan University, KSA

September 1, 2011-June 30, 2011

SAR 165,000

3. Title

Role in Project

Awarding body

Award period

Funding Amount

Mechanistic approach of tellurium toxicity

Principal Investigator

Research Deanship, Jazan University, KSA

October 2014 – September 2015

SAR 60,000

4. Title

Role in Project

Awarding body

Award period

Funding Amount

Formulation and encapsulation of nanoparticles of curcumin

and piperine for the treatment of cerebral ischemia.

Co-Principal Investigator

KACST, Jazan

October 2014 – September 2016

SAR 2,000,000 (2 million)

PATENT:

Title: “Production and purification of the antibiotic Xenohagxin from Exnorhabdus

indica”

Year of patent: 06-11-2014

Patent Approval Number: 114350583

Patent Approved by KACST, Saudi Arabia

SCIENTIFIC ABSTRACTS:

1. Hussein Abdelhady Aboulhag, Mohammed M. Safhi. F-258- Xenohagxin: New

proteinaceous antibiotic derived from Xenorhabdus indica. American Society for

Microbiology Sept 5-6, 2014, Washington DC, USA.

2. Barik B. B, M. M. Safhi, Santanu Ghosh. A comparative BA/BE study of

conventional and sustained-release tablet formulations of Aceclofenac in healthy

male subject. 4th

World Congress on "Bioavailability and Bioequivalence:

Pharmaceutical R&D Summit, 20-22 May 2013, Beijing, China.

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3. Hussein Abdelhady Aboulhag, Mohammed M. Safhi. Assessment of immune

response against HIV-1 P24 antigen using Bacillus thuringiensis serovar Dakota

(H15) activated delta-endotoxin as an adjuvant. American Association of

Immunologists (AAI) Annual Meeting, Immunology 2013, May 3-7, Honolulu,

Hawaii.

4. S. M. Kumar, Mohammed M. Safhi. Vaccine adjuvants- present and future concepts.

BIT's 5th

Annual World Congress of vaccine 2013, Hangzhou, China.

5. Tamanna Jahangir, Mohammad M. Safhi. A natural compound alleviates

hepatotoxicity in Wistar rats: possible role of NfKB, caspases? ECOPRAM 2012,

Istanbul,Turkey.

6. Tamanna Jahangir, Mohammad M. Safhi. Natural plant product protects against 2-

acetoaminoflourine induced hepatotoxicity. 4th

World cancer congress May 22-25,

2011, Dalian ,China

7. Abouelhag HA, Safhi MM. Agarose slide elisa for diagnosis of HCV-AB in rural

areas. Presented in the 18th Annual meeting of the American Association of

Immunology held on May 13-17, 2011.

8. Barik B, Safhi MM, Dinda A, Biswal I. Preparation of Budesonide loaded

nanoparticles: Effect of stabilizers. Presented in fourth annual nanotechnology

symposium held on September 23-24, 2011 in Sullivan University College of

Pharmacy, Louisville, Kentucky, USA.

9. Safhi MM. Priming of STATs for cytokine-triggered polyubiquitylation and

degradation upon A2A adenosine receptor (A2AAR) expression in vascular

endothelial cells. Life Science July 8-12, 2007, Glasgow, UK.

10. Safhi MM. Priming of STAT1 and STAT3 for cytokine-triggers degradation by the

proteasome upon A2A Adenosine receptor (A2AAR) expression in human umbilical

vein endothelial cells. Bioscience 23-27, 2006, Glasgow, UK.

PUBLICATIONS:

1. Rizwana Tabassum, Kumar Vaibhav, Pallavi Shrivastava,Andleeb Khan, Mohd

Ejaz Ahmed, Mohammad Ashafaq, M Badruzzaman Khan, Farah Islam,

Mohammed M Safhi, Fakhrul Islam. Perillyl alcohol improves functional and

histological outcomes against ischemia-reperfusion injury by attenuation of

oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral

artery occlusion rats. European Journal of Pharmacology 2015; 747: 190-199 doi:

10.1016/j.ejphar.2014.09.015 (Impact Factor - 2.68)

2. Hayate Javed, Kumar Vaibhav, M Ejaz Ahmed, Andleeb Khan,Rizwana

Tabassum, Farah Islam, Mohammed M Safhi, Fakhrul Islam. Effect of hesperidin

on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in

intracerebroventricular streptozotocin induced cognitive impairment in mice.

Journal of Neurological Sciences 2015; 348(1-2): 51-59 doi:

10.1016/j.jns.2014.10.044. (Impact Factor - 2.26)

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3.Mohammad Sarfaraz Alam, Mohammad Sajid Ali, Mohammad Intakhab Alam,

Tarique Anwer, Mohammed Mohsen A Safhi. Stability Testing of Beclomethasone

Dipropionate Nanoemulsion. Tropical Journal of Pharmaceutical Research,

January 2015; 14 (1): 15-20.

4. Nakul Gupta, Mohammed M. Safhi, Yousra Nomier, Maryam Nayeem, Syed

Mamoon Husain, Pankaj Tripathi, Meetu Agarwal. Chemoprotective Effect of

Leucas aspera Plant in Rats: DEN Induced Hepatocarcinogenesis. International

Journal of Pharmaceutical Sciences Review and Research 2015; 30(1):22-27.

5. Mohammed M Safhi, Alam MF, Hussain S, Siddiqui MAH, Khuwaja G, Khardali

IAJ, Al-Sanosi RM, Islam F. Cathinone, an active principle of Catha edulis,

accelerates oxidative stress in the limbic area of Swiss albino mice. Journal of

Ethnopharmacology 2014; 156; 102-106. (Impact Factor - 2.93)

6. Andleeb Khan, Kumar Vaibhav, Hayate Javed, Rizwana Tabassum, Md Ejaz

Ahmed, Mohd Moshahid Khan, M Badruzzaman Khan, Pallavi Shrivastava, Farah

Islam, M Saeed Siddiqui, M. M. Safhi, Fakhrul Islam. 1,8-Cineole (Eucalyptol)

Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to

Alzheimer's Disease. Neurochemical Research 2014; 39: 344 – 352. DOI

10.1007/s11064-1231-9 (Impact Factor - 2.13)

7.Gyas Khan, S. E. Haque, Tarique Anwer, M. N. Ahsan, M.M. Safhi, M. F. Alam.

Cardioprotective effect of green tea extract on doxorubicin-induced cardiotoxicity in

rats. Acta Poloniae Pharmaceutica - Drug Research 2014; 71(5): 861-868.

(Impact Factor – 0.67)

8.Masoom Raza Siddiqui, Md. Sarfaraz Alam, Mohammed M. Safhi, Md. Sajid Ali.

Application of Persulphate for the Quantitative Analysis of Ceftriaxone in

Pharmaceutical Formulations. Advanced Science, Engineering and Medicine 2014;

6(2):231-234.

9. Mohammed M. Safhi, Mohammad Firoz Alam, S.M. Sivakumarb, Aamena Jabeen,

Tarique Anwer, Gyas Khan, Fakhrul Islam. Antibacterial spectrum of black seed oil

against selected human pathogenic bacteria. Journal of Pharmacy Research 2014:

8(11); 1726-1728

10. Mohammed M Safhi, Sivakumar S, Aamena Jabeen, Foziya Zakir, Farah Islam,

B.B Barik. Chitosan nanoparticle as a sustained Penicillin G delivery prepared by

ionic gelatin technique. Journal of Pharmacy Research 2014: 8(10); 1352-1354.

11. Mohammed M Safhi, Alam MF, Khardali IAJ, Hussain S, Siddiqui MAH,

Khuwaja G, Al-Sanosi RM, Islam F. Toxic effect of cathinone (an active principle

of Catha edulis) on brain lipids in Swiss albino mice. Environment Conservation

Journal 2014; 15(1&2): 5-11. (Impact Factor – 0.58)

12. Mohammed M Safhi. Seaweed as potential resources of antimicrobials “An

Outline”. Research J. Pharm Tech 2014; 7(10): 1178-1180.

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13. Nakul Gupta, Prerna Chauhan, Maryam Nayeem, Mohammed M Safhi, Meetu

Agarwal. Hepatoprotective effect of Caesalpinia crista Linn. against CCl4 and

paracetamol induced hepatotoxicity in albino rats. African Journal of Pharmacy

and Pharmacology 2014; 8(18): 485-491. (Impact Factor – 0.84)

14. Meetu Agarwal, Maryam Nayeem, Mohammed M Safhi, Nakul Gupta, Hafiz A

Makeen, Jameel MY Sumaily. Prescribing pattern of drugs in the department of

Obstetrics and Gynecology in expected mothers in Jazan region, KSA.

International Journal of Pharmacy and Pharmaceutical Sciences 2014; 6(1):

658-661. (Impact Factor – 1.59)

15. Alam MF, Mohammed M Safhi, Sivakumar SM, Anwer T, Khan G, Islam F.

Antibacterial toxicity of sodium tellurite (ST) against selected bacterial strains.

Research J. Pharm Tech 2014; 7(5): 499-501.

16. Sivakumar S. M, Mohammed M Safhi, Bhakti B Barik. Nanoparticles for

triggering and regulation of immune response of vaccines: Perspective and

prospective. Current Pharmaceutical Biotechnology 2013: 14; 1242-1249. Impact

Factor - 2.69)

17. Kumar Vaibhav, Pallavi Shrivastava, Rizwana Tabassum, Andleeb Khan, Hayate

Javed, Md. Ejaz Ahmed, Farah Islam, M. M. Safhi, Fakhrul Islam. Delayed

administration of zingerone mitigates the behavioral and histological alteration via

repression of oxidative stress and intrinsic programmed cell death in focal transient

ischemic rats. Pharmacol Biochem Behav 2013; 15(113): 53-62. DOI:

10.1016/j.pbb.2013.10.008. (Impact Factor - 2.61)

18. Javed H, Khan A, Vaibhav K, Moshahid Khan M, Ahmad A, Ejaz Ahmad M,

Ahmad A, Tabassum R, Islam F, Safhi M.M, Islam F. Taurine ameliorates

neurobehavioral, neurochemical and immunohistochemical changes in sporadic

dementia of Alzheimer's type (SDAT) caused by intracerebroventricular

streptozotocin in rats. Neurological Sciences 2013; 34 (12): 2181-2192. DOI

10.1007/s00709-013-0482-2. (Impact Factor – 1.41)

19. Ahmad ME, Javed H, Khan MM, Vaibhav K, Ahmad A, Khan A, Tabassum R,

Islam F, Safhi MM, Islam F. Attenuation of oxidative damage-associated cognitive

decline by Withania somnifera in rat model of streptozotocin-induced cognitive

impairment. Protoplasm 2013; 250(5): 1067-1078. DOI 10.1007/s00709-013-0482-

2. (Impact Factor - 2.86)

20. Kumar Vaibhav, Pallavi Shrivastava, Andleeb Khan, Hayate Javed ,Rizwana

Tabassum, Md. Ejaz Ahmed, M. Badruzzaman Khan, Mohd. Moshahid Kha, Farah

Islam, Sayeed Ahmad, M. Saeed Siddiqui, Mohammed M. Safhi, Fakhrul Islam.

Azadirachta indica mitigates behavioral impairments, oxidative damage,

histological alterations and apoptosis in focal cerebral ischemia–reperfusion model

of rats. Neurological Sciences 2013 Aug; 34(8): 1321-30. DOI 10.1007/s10072-

012-1238-z. (Impact Factor – 1.41)

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21. Rizwana Tabassum, Kumar Vaibhav, Pallavi Shrivastava, Andleeb Khan, Md. Ejaz

Ahmed, Hayate Javed, Farah Islam, Sayeed Ahmad, M. Saeed Siddiqui,

Mohammed M. Safhi, Fakhrul Islam. Centella asiatica attenuates the

neurobehavioral, neurochemical and histological changes in transient focal middle

cerebral artery occlusion rats. Neurological Sciences 2013 Jun; 34(6): 925-33. DOI

10.1007/s10072-012-1163-1. (Impact Factor – 1.41)

22. Pallavi Shrivastava, Kumar Vaibhav, Rizwana Tabassum, Andleeb Khan, Tauheed

Ishrat, Mohd Moshahid Khan, Ajmal Ahmad, Farah Islam, Mohammed M.

Safhi, Fakhrul Islam. Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-

OHDA induced Parkinson's Rat model. Journal of Nutritional Biochemistry 2013

Apr; 24(4): 680-687; DOI:10.1016/j.jnutbio.2012.03.018. (Impact Factor – 4.29)

23. Ahmed ME, Khan MM, Javed H, Vaibhav K, Khan A, Tabassum R, Ashafaq M,

Islam F, Safhi MM, Islam F. Amelioration of cognitive impairment and

neurodegeneration by catechin hydrate in rat model of streptozotocin-induced

experimental dementia of Alzheimer's type. Neurochem Int. 2013 Mar; 62(4):492-

501.; 62(4): 492-501. (Impact Factor - 2.66)

24. Raza SS, Khan MM, Ahmad A, Ashafaq M, Wagner AP, Safhi MM, Islam F.

Neuroprotective effect of naringenin is mediated through suppression of NF-κB

signaling pathway in experimental stroke. Neuroscience 2013; 230: 157-171

(Impact Factor – 3.12)

25. S. M. Kumar, Mohammed M. Safhi. Isolation and screening of bioactive principle

from Chaetomorpha antennina against certain bacterial strains. Saudi

Pharmaceutical Journal 2013; 21: 119-121 (Impact Factor – 0.95)

26. S. M. Kumar, Mohammed M. Safhi, Aamena Jabeen, Kannadasan M.

Pharmaceutical aspects of Chitosan polymer “In Brief”. Research J. Pharm Tech

2013; 6(12): 1439 – 1442

27. Gupta Nakul, Sharma Ishan, Meetu Agarwal, Mohammed M Safhi, Chauhan

Prerna, Tarique Anwer, Gyas Khan. Antidiabetic activity of seed extract of

Caesalpinia crista Linn. in experimental animals. African Journal of Pharmacy

and Pharmacology 2013; 7(26): 1808-1813. (Impact Factor – 0.84)

28. Tarique Anwer, Manju Sharma, Gyas Khan, Muzaffar Iqbal, Md Sajid Ali, Md

Sarfaraz Alam, Mohammad M. Safhi, Nakul Gupta. Rhus coriaria ameliorates

insulin resistance in non-insulin dependent diabetes mellitus (NIDDM) rats. Acta

Poloniae Pharmaceutica-Drug Research 2013; 70(5): 861-867. (Impact Factor –

0.67)

29. Md. Sajid Ali, Md. Sarfaraz Alam, Nawazish Alam, Tarique Anwer, M. M. Safhi.

Accelerated Stability Testing of Clobetasol Propionate Loaded Nanoemulsion as per

ICH Guideline. Scientia Pharmaceutica 2013; 81: 1089–1100. DOI

10.3797/scipharm.1210-02

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30. Anugeetha Thacheril Mohanan, Suba Venkatesan, Nithya Sermugapandian,

Mohammed Al-Safhi, Gyas Khan. Attenuating effect of Cilostazol against

vincristine – Induced neuropathic pain in mice. Journal of Pharmacy Research

2013; 6(5):579–582. (Impact Factor – 0.6)

31. Tamanna Jahangir, Mohammed M Safhi, Sarwat Sultana, Sayeed Ahmad. Pluchea

lanceolata protects against Benzo(a) pyrene induced renal toxicity and loss of DNA

integrity. Interdiscip Toxicol. 2013 March; 6(1): 47–54.

32. Gupta Nakul, Mohammed M Safhi, Jameel M. Y Suamily, Meetu Agarwal. Drug

prescribing patterns in children registered in the department of pediatric of Jizan

General Hospital of Jazan, KSA. International Journal of Pharmacy and

Pharmaceutical Sciences 2013; 5(4): 397-399. (Impact Factor – 1.59)

33. Md Sarfaraz Alam, Md Sajid Ali, Nawazish Alam, Massom Raza Siddiqui, Md

Shamim, M.M. Safhi. In Vivo study of clobetasol propionate loaded nanoemulsion

for topical application in psoriasis and atopical dermatitis. Drug Invention Today

2013; 5: 8-12.

34. Md. Intakhab Alam, Nawazish Alam, Md. Sajid Ali, Vikramjit Singh, Mohammed

M. Safhi, Md. Sarfaraz Alam, Tarique Anwer. Type, preparation and evaluation of

transdermal patch: a review. World Journal of Pharmacy and Pharmaceutical

Sciences 2013; 2(2): 2199-2233.

35. Mohammed M. Safhi. Spectrophotometric method for the estimation of Clinidipine

in bulk and pharmaceutical dosage forms. Oriental Journal of Chemistry 2013;

29(1): 131-134

36. Khan Hina, Gupta Nakul, Mohammed M Safhi, Meetu Agarwal, Khan Gyas,

Mohan Govind. Antiulcer activity of seed extracts of Gynocardia odorata Roxb. On

pylorus ligation and indomethacin induced gastric leision in albino rats.

International Journal of Development Research 2013; 3(5): 49-54.

37. Sharma Ishan, Gupta Nakul, Mohammed M Safhi, Meetu Agarwal, Chauhan

Prerna. Antipyretic activity of Caesalpinia crista Linn. seeds extract in

experimental animals. International Journal of Current Research May 2013; 5(5):

1202-1205

38. Mohammed M. Safhi, Makssod Ali, S. M. Sivakumar, Aamena Jabeen, Manoharaj

Y. N. Antibacterial studies of Catharanthus roseus of Jazan province against the

selected bacterial strains. Research J. Pharm Tech March 2013; 6(4): 403-405

39. Mohammed M. Safhi, Manoharaj Y. N. Development and validation of a rapid

stability indicating chromatographic determination of Clinidipine in bulk dosage

form. Research J. Pharm Tech March 2013; 6(3): 296-299

40. Mohammed M. Safhi. In vitro antibacterial screening of some commercially

available sodium flusidate ointment. Research J. Pharm Tech March 2013; 6(3):

289-291

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41. Ahmad A, Khan MM, Raza SS, Javed H, Ashafaq M, Islam F, Safhi M.M, Islam F.

Ocimum sanctum attenuates oxidative damage and neurological deficits following

focal cerebral ischemia/reperfusion injury in rats. Neurol Sci. 2012 Dec;

33(6):1239-47. doi: 10.1007/s10072-012-0940-1. (Impact Factor – 1.41)

42. Khan A, Vaibhav K, Javed H, Khan MM, Tabassum R, Ahmed ME, Srivastava P,

Khuwaja G, Islam F, Siddiqui MS, Safhi MM, Islam F. Attenuation of Aβ-induced

neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and

oxidative stress. Mol Cell Biochem 2012 Oct; 369(1-2): 55–65. (Impact Factor -

2.33)

43. Ahmad A, Khan MM, Javed H, Raza SS, Ishrat T, Khan MB, Safhi M.M, Islam F.

Edaravone ameliorates oxidative stress associated cholinergic dysfunction and

limits apoptotic response following focal cerebral iscameia in rats. Molecular and

Cellular Biochemistry 2012 Aug; 367(1-2): 215-25. doi: 10.1007/s11010-012-

1335-6. (Impact Factor – 2.33)

44. Mohammad Ashafaq, Syed Shadab Raza, Mohd. Moshahid Khan, Ajmal Ahmad,

Hayate Javed, Md. Ejaz Ahmad, Rizwana Tabassum, Farah Islam, M. Saeed

Siddiqui, Mohammed M. Safhi, Fakhrul Islam. Catechin Hydrate Ameliorates

Redox Imbalance and Limits Inflammatory Response in Focal Cerebral Ischemia

Neurochemical Research 2012 Aug; 37(8): 1747-60. DOI 10.1007/s11064-012-

0786-1 (Impact Factor – 2.13)

45. Kumar Vaibhav, Pallavi Shrivastava, Hayate Javed, Andleeb Khan, Md. Ejaz

Ahmed, Rizwana Tabassum, Mohd. Moshahid Khan, Gulrana Khuwaja, Farah

Islam, M. Saeed Siddiqui, Mohammed M. Safhi, Fakhrul Islam. Piperine

suppresses cerebral ischemia–reperfusion-induced inflammation through the

repression of COX-2, NOS-2, and NF-jB in middle cerebral artery occlusion rat

model. Molecular and Cellular Biochemistry 2012 Aug; 367(1-2):73-84; DOI

10.1007/s11010-012-1321-z. (Impact Factor – 2.33)

46. H Javed, M M Khan, A Ahmad, K Vaibhav, M E Ahmad, A Khan, M Ashafaq, F

Islam, M S Siddiqui, M M Safhi. Rutin prevents cognitive impairments by

ameliorating oxidative stress and neuroinflammation in rat model of sporadic

dementia of Alzheimer type. Neuroscience 2012; 210: 340-52. (Impact Factor –

3.12)

47. Khan MM, Raza SS, Javed H, Ahmad A, Khan A, Safhi MM, Islam F. Rutin

Protects Dopaminergic Neurons from Oxidative Stress in an Animal Model of

Parkinson’s Disease. Neurotox Res 2012 Jul; 22(1): 1-15.doi: 10.1007/s12640-

011-9295-2. (Impact Factor – 2.87)

48. Mohammad Ashafaq, Mohd. Moshahid Khan, Syed Shadab Raza, Ajmal Ahmad,

Gulrana Khuwaja, Hayate Javed, Andleeb Khan, Farah Islam, M. Saeed Siddiqui,

Mohammed M. Safhi, Fakhrul Islam. S-allyl cysteine mitigates oxidative damage

and improves neurologic deficit in a rat model of focal cerebral ischemia. Nutrition

Research Feb 2012; 32: 133–143. (Impact Factor – 1.20)

49. Waquar ahsan, Mohammed M. Safhi, Nadeem Sidiqui, Shamama Javed, M.

Shamser Alam, Bismillah Azad, Javed Akhter. An insight into the new

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anticonvulsant Agents. Current topics in Medicinal Chemistry, 2012, 12 1072-

1092. (Impact Factor – 4.47)

50. Tarique Anwer, Manju Sharma, K. K. Pillai, Gyas Khan and Mohammad M. Safhi.

Antihyperglycemic, antidyslipidemic and antioxidant activity of Rhus coriaria in

STZ-induced type 2 diabetic rats. African Journal of Pharmacy and

Pharmacology 2012; 6(41): 2851-2855. (Impact Factor – 0.84)

51. Mohammed M. Safhi, El-Hag HA. Agarose slide ELISA for diagnosis of HCV-AB

in rural areas. Journal of American Science 2012; 8(12): 865-871.

52. Sivakumar SM, Safhi MM, Kannadasan M, Sukumaran N. Vaccine adjuvants-

current status and prospects on controlled release adjuvancity. Saudi

Pharmaceutical Journal 2011; 19(4): 197-206. (Impact Factor – 0.95)

53. Alam MF, Safhi MM, Chopra AK. In vitro anti-malarial activity of aerial part of

Boenning hausenia albiflora. Env Conservation J 2011; 12(3): 7-11

54. Safhi MM. Novel spectrophotometric method for theestimation of Nisoldipine in

bulk and pharmaceutical dosages forms. Der Pharma Chemica 2011; 3(4): 275-

278.

55. Safhi MM and Anwer T. Comparative analysis of Withania somnifera and Rhus

coriaria on hyperglycemia and insulin sensitivity in type 2 diabetic rats. J Jazan

University 2011; 1 (1): 1-14.

56. Safhi MM. Formulation and in vitro evaluation of sustained release intra gastric

tablets of propranolol hydrochloride using natural polymer. J Pharmaceutical

Biomedical Sciences 2011; 10 (10): 1-6.

57. Nagaraj MY and Safhi MM. Rapid RP-HPLC method for estimation of nisoldipine

from tablet dosage form. Der Pharmacia Sinica. 2011; 2 (6): 122-126

58. El-Hag HA and Safhi MM. Antimalignancy activity of Bacillus thuringiensis

Serovar Dakota (H15) in vivo. World J Medical Sciences 2011; 6(1): 6-16.

59. Moni SS, Natarajapillai S, Safhi, MM. Immune augmentation of injectable PLGA-

Dextran (PLDEX) a double polymeric microspheres as an adjuvant for Hepatitis B

vaccine. World J Vaccine 2011, 1: 104-108.

60. Alam MF, Safhi MM, Chopra AK and Dua VK. Toxicological properties of several

medicinal plants from the Himalayas (India) against vectors of malaria, filariasis

and dengue. Tropical Biomedicine 2011; 28 (2): 343-350. (Impact Factor – 0.92)

61. Sachinkumar Vasantrao Patil, S. K. Sahoo, A. L. Behera, B. B. Barik, M. M. Safhi.

Consequences of Formulation Variables on Physicochemical Properties of Indinavir

Sulfate Microspheres. Jordan Journal of Pharmaceutical Sciences 01/2011;

4(3):251-260.

62. Dinda A, Biswal I, Das D, Si S, Kumar S, Barik BB, Safhi MM. Effect of

stabilizers and process parameters for budesonide loaded PLGA-nanoparticles.

International J Drug Delivery 2011; 3: 371-380.

12

63. Alam MF, Chopra AK, Safhi MM and Dua VK. Toxicity of Vernonia anthelmintica

Linn. (Asteracea) seeds against mosquitoes vectors. J Applied and Natural Science

2010; 2 (2): 190-193.

64. Raza SS, Khan MM, Ashafaq M, Ahmad A, Khuwaja G, Khan A, Siddiqui MS,

Safhi MM, Islam F. Silymarin protects neurons from oxidative stress associated

damages in focal cerebral ischemia: A behavioral, biochemical and

immunohistological study in Wistar rats. Journal of Neurological Sciences 2011

Oct; 309(1-2):45-54. (Impact Factor – 2.32)

65. Raza SS, Khan MM, Ahmad A, Ashafaq M, Khuwaja G, Tabassum R, Javed H,

Siddiqui MS, Safhi MM, Islam F. Hesperidin ameliorates functional and

histological outcome and reduces neuroinflammation in experimental stroke. Brain

Research 2011 Oct; 1420: 93-105. (Impact Factor – 2.46)

66. Ahmad A, Khan MM, Hoda MN, Raza SS, Khan MB, Javed H, Ishrat T, Ashafaq

M, Ahmad ME, Safhi MM, Islam F. Quercetin Protects Against Oxidative Stress

Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and

Reperfusion. Neurochemical Research 2011 Aug; 36(8):1360-71. (Impact Factor

– 2.13)

67. Javed H, Khan MM, Khan A, Vaibhav K, Ahmad A, Khuwaja G, Ahmed ME, Raza

SS, Ashafaq M, Tabassum R, Siddiqui MS, El-Agnaf OM, Safhi MM, Islam F. S-

allyl cysteine attenuates oxidative stress associated cognitive impairment and

neurodegeneration in mouse model of streptozotocin-induced experimental

dementia of Alzheimer's type. Brain Res. 2011; 10; 1389: 133-42. (Impact Factor

– 2.46)

68. Khuwaja G, Khan MM, Ishrat T, Raza SS, Khan A, Javed H, Khan MB, Safhi MM

and Islam F. Neuroprotective effects of curcumin on 6-hydroxydopamine-induced

Parkinsonism in rats: Behavioral, neurochemical and immunohisto-chemical

studies. Brain Res. 2011; 1368: 254-63. (Impact Factor – 2.46)

69. Khan MM, Hoda MN, Ishrat T, Ahmad A, Khan MB, Khuwaja G, Raza SS, Safhi

MM, Islam F. Amelioration of 1[methyl-4-phenyl-1,2,3,6-tetrahydropyridine-

inducedbehavioral dysfunction and oxidative stress by Pycnogenol in mouse model

of Parkinson's disease. Behav. Pharmacol. 2010; 21(5-6): 563-71. (Impact Factor

– 2.85)

70. Safhi MM, Rutherford C, Ledent C, Sands WA, Palmer TM. Priming of signal

transducer and activator of transcription proteins for cytokine-triggered

polyubiquitylation and degradation by the A 2A adenosine receptor. Molecular

Pharmacology 2010; Vol. 77 (6):968-78. (Impact Factor –4.53)

71. Safhi MM. Prevalence of Sickle Cell Disease in Population of Jazan Region, Saudi

Arabia. Ain Shams Science Bulletin 2009; Vol. 47: 21-27.