curriculum vitae · curriculum vitae. k. eshav . k s. ingh, p. h.d . c itizenship united states of...

Curriculum Vitae

KESHAV K SINGH, PH.D

CITIZENSHIP UNITED STATES OF AMERICA (NATURALIZED) OVERSEAS CITIZEN OF INDIA CURRENT APPOINTMENTS Joy and Bill Harbert Endowed Chair in Cancer Genetics

Professor of Genetics Professor of Pathology Professor of Environmental Health Director, Cancer Genetics Program, University of Alabama Comprehensive Cancer Center

ADDRESS Office: Department of Genetics School of Medicine University of Alabama at Birmingham Hugh Kaul Genetics Building, Suite 620 720, 20th Street South Birmingham, AL 35294-0024 Telephone: 205-934-2750

Fax: 205-934-2766 Email: [email protected] EDUCATION AND TRAINING 1989 Doctor of Philosophy, University of Wollongong, Wollongong, New South Wales, Australia 1981 Master of Science, G.B. Pant University of Agriculture and Technology Pant Nager, Uttar Pradesh, India 1978 Bachelor of Science, Rohilkhand University, Bareilly, Uttar Pradesh, India PROFESSIONAL EXPERIENCE RESEARCH 2011- Joy and Bill Harbert Endowed Chair in Cancer Genetics, University of

Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL 2011- Director, Cancer Genetics Program, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL 2011- Professor of Genetics, Department of Genetics, School of Medicine, University

of Alabama at Birmingham, AL

mailto:[email protected]

Curriculum Vitae Keshav K. Singh, Ph.D.

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2011- Professor of Pathology, Department of Pathology, School of Medicine University of Alabama at Birmingham, AL

2011- Professor of Environmental Health, Department of Environmental Health, School of Public Health, University of Alabama at Birmingham, AL

2011- Senior Scientist, Center for Free Radical Biology and Medicine, University of Alabama at Birmingham, AL

2011- Senior Scientist, Center for Aging, University of Alabama at Birmingham, AL 2011- Senior Scientist, Comprehensive Diabetes Center, University of Alabama at

Birmingham, AL 2010-2011 Distinguished Professor of Oncology, Department of Cancer Genetics, Roswell

Park Cancer Institute, Buffalo, NY 2006-2010 Professor of Oncology/ Professor of Molecular and Cellular Biology,

Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 2003-2006 Associate Professor of Oncology/ Molecular and Cellular Biology, Department

of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 1996-2002 Assistant Professor of Oncology, Sidney Kimmel Cancer Center, Johns

Hopkins School of Medicine, Baltimore, Maryland 1997-2002 Assistant Professor of Environmental Health, Johns Hopkins School of Public

Health, Baltimore, Maryland 1992-1996 Postdoctoral Research Fellow, Harvard University, Boston, Massachusetts 1989-1992 Postdoctoral Research Fellow, University of Florida, Gainesville, Florida 1984 Summer Research Fellow, Marine Biological Laboratory, Woods Hole 1982-1983 Junior Research Fellow, Division of Microbiology, Central Drug Research Institute, Lucknow, India TEACHING 2010 Co-Director, Seminar Course in Cancer Genetics, BIR 501, Roswell Park Cancer Institute 2006 Co-Director, Seminar Course in Cancer Genetics, BIR 501, Roswell Park Cancer Institute 2004 Co-Director, Radiation Biology Course, BPR 525, Roswell Park Cancer Institute 1999-2003 Faculty, Molecular Toxicology Course, Department of Environmental Health,

Johns Hopkins 1999-2003 Faculty, Radiobiology Course, Division of Radiation Oncology, Johns Hopkins 1985 Supervisor, Department of Biology, University of Wollongong, Australia 1984-1987 Demonstrator, Department of Biology, University of Wollongong, Australia 1980-1981 Teaching Assistant, Department of Microbiology, G.B. Pant University of Agriculture and Technology, India RECOGNITION/AWARDS 2012 Outstanding Achievement Award, American Asian Scientists in Cancer

Research, AACR-103rd Annual Meeting 2012, Chicago.


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2008 Visiting Professorship, Department of Radiation Oncology, Holden Comprehensive Cancer Center, Iowa City, Iowa.

2008 Adjunct Professor, Manipal University, Manipal, India. 2005 Visiting Professorship, Supported by Ministry of Education, Science, Sports, Culture and Technology of Japan 2005 Profiled among Buffalo-Niagara’s Top Researchers by Bufflink News Magazine, Vol. 3, Issue 2, February 2005. 2003 Visiting Professorship, Supported by Ministry of Education, Science, Sports, Culture and Technology of Japan 2003 National Register’s Who’s who Executives and Professional 1999-2002 Scientist Development Award, American Heart Association, Dallas 1998-1999 FIRST Award, National Institute of Environmental Health, National Institute of Health, Bethesda 1992-1996 Individual National Research Service Award, National Cancer Institute, National Institutes of Health, Bethesda 1989-1991 Postdoctoral Research Fellowship, American Heart Association, Florida 1984 Fellowship. Marine Biological Laboratory, Woods Hole, Massachusetts 1983-1987 Postgraduate Research Award, University of Wollongong, Australia 1982-1983 Junior Research Fellowship, Council of Scientific and Industrial Research, India 1980 First Rank in M.S. Major in Microbiology, G.B. Pant University of Agriculture and Technology, India 1979-1981 Graduate Teaching Assistantship. G.B. Pant University of Agriculture and Technology, India 1976-1978 Bursary Scholarship, Rohilkhand University, India 1973-1975 Merit Scholarship, Board of Higher Education, India LEADERSHIP ROLE

Founding Editor-in-Chief, Cancer Health Disparities Journal (www.cancerhealthdisparities.org) Organizer, Minisymposium on Mitochondria, Metabolism and Epigenetics, Doubletree, Birmingham, 2016. Expert panellist invited to a National Cancer Institute workshop to develop future strategies on Mitochondrial Information Transfer, National Institute of Health, 2014. Chair, NCI workshop on mtDNA and epidemiology of cancer (This initiative has resulted in NCI R01 and R21 program announcement on Mitochondria in Cancer Epidemiology, Detection, Diagnosis and Prognosis http://grants.nih.gov/grants/guide/pa-files/PA-08-143.html) Founding Editor-in-Chief, Mitochondrion Journal

Founder, The Mitochondria Research Society (www.mitoresearch.org)

http://www.cancerhealthdisparities.org/

http://grants.nih.gov/grants/guide/pa-files/PA-08-143.html

http://www.mitoresearch.org/


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Member, Mitochondrial Disease Coordination Committee Member, Mitochondrial Task Force for NIH Roadmap Initiative (This effort has resulted in NIH roadmap initiative on functional variation in mitochondria http://nihroadmap.nih.gov/) Founder, Society for Mitochondrial Research and Medicine, India (www.inmit.org)

Instituted Professor Anthony Linnane Award for Young Scientists Instituted Outstanding Paper Award for the Mitochondrion Journal for Young Scientists

INDUSTRY EXPERIENCE Consultant, Transgenomic, Inc. Consultant, Genesis Genomics, Inc.

POSTDOCTORAL FELLLOWS AND STUDENTS TRAINED PREVIOUS Post Doctoral Fellows Hasmat Sikder Ph.D., Barbara Sigala Ph.D., Christine Schwimmer Ph.D., Robert Delsite, Ph.D., Aditi Chateerjee Ph.D., Sushant Kacchap Ph.D., Shaoyu Zhou Ph.D., Mokhtar Desouki M.D., Ph.D., Henshan Zhang M.D., Ph.D., Tanbir Najrana Ph.D., Olga Moiseeva Ph.D., R. Jayakumar Ph.D., Peter Schneider, Ph.D., Andrea Varga Ph.D., Zahra Fayazi D.V.M Ph.D.. Jorge Lima Ph.D., Kelly Seyed, Ph.D., Vanniarajan Ayyasamy, Ph.D., Kjerstin Owens Ph.D., Xiurong Li MD. Ph.D., Satyajit Patra Ph.D. Changhchun Ren, M.D., Ph.D., Ved Prakash Mooga, Ph.D. Research Instructor Bhupendra Singh, Ph.D Laboratory Technician Christiane Houde, B.S. Marija Vucjic, B.S. Ph.D. Student Anna Rasmussen, Roskilde University, Denmark Brandon Hall, Roswell Park Cancer Institute, Buffalo, NY Trevor Carden, University of Alabama at Birmingham, Birmingham, AL. PH.D. THESIS COMMITTEES Timothy Johnson, Department of Cancer Genetics, Roswell Park Cancer Institute Laksmi Ramachandran, Department Cellular Stress Biology, Roswell Park Cancer Institute

http://nihroadmap.nih.gov/

http://www.inmit.org/


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Shruti Nagar, Department of Radiation Oncology, University of Maryland, School of Medicine, Thesis Advisor: William F. Morgan, Professor and Director, Division of Radiation Biology Grace Kim, Department of Radiation Oncology, University of Maryland, School of Medicine, Thesis Advisor: William F. Morgan, Professor and Director, Division of Radiation Biology Diane Wonsey, Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Thesis Advisor: Chi Van Dang, M. D., Ph. D., Vice Executive Dean, Johns Hopkins School of Medicine Chou Wen-Chien, Department of Molecular Biology and Genetics, Johns Hopkins School of Medicine, Thesis Advisor: Chi Van Dang, M. D., Ph. D., Vice Executive Dean, Johns Hopkins School of Medicine Haley Albright, Ph.D. Student, Department of Genetics, UAB School of Medicine Brian Spurlock, Ph.D. Student, Department of Genetics, UAB School of Medicine Jennifer A Stanley, M.D. Ph.D, Student, Department of Radiation Oncology, UAB School of Medicine. Trung Tom Vu, Ph.D. Student, Division of Hematology and Oncology, UAB School of Medicine Master’s Student Meghna Schroff, Shrikant Ganeshan, Gretchka Mair, Kelly Burke Undergraduate Students Grace Kim, Hok Koi, Kiran Ramatuni, Mekha George Minority Summer Students Agatha Lee, Charles Kyte PRESENT Post Doctoral Fellows Prachi Bajpai, Ph.D. Noha Ahmad, MD. Ph.D. PH.D. THESIS COMMITTEES Brian Spurlock, Ph.D. Student, Department of Genetics, UAB School of Medicine INTERNATIONAL THESIS EXAMINER:


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Katti Prasanna, Department of Molecular Reproductive Development and Genetics. Indian Institute of Science (IISc), Bangalore, India, 2016.

Nima Borhan Fakouri, Graduate School of Health and Medical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen N, Denmark, 2017 Jon Ambæk Durhuus, Graduate School of Health and Medical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen Copenhagen N, Denmark, 2017 SABBATICAL VISITORS Lene J. Rasmussen, Ph.D, Department of Life Sciences, Roskilde University, Denmark FULLBRIGHT VISITOR: Pedro Pinheiro, Ipatimup - Instituto Patologia e Imunologia Molecular Universidade do Porto, PORTO UAB COMPREHENSIVE CANCER CENTER ACTIVITIES Director, Cancer Genetics Program Member, Cancer Center Recruitment Committee Member, Cancer Center Director’s Council Member, Strategic Planning Committee on Genomics and Proteomics Member, Promotion and Tenure Committee, Department of Genetics, UAB School of Medicine. ROSWELL PARK CANCER INSTITUTE ACTIVITIES COMMITTEES Member, Search Committee, Department of Cancer Genetics Faculty Recruitment Member, Roswell Park Alliance Foundation Scientific Advisory Committee Member, Conflict of Interest Committee Member, Search Committee, Chair Department of Surgical Oncology Member, Proteomics Steering Committee Member, Grant Writing Workshop Member, Tactical Task Force on “New Agents” in Cancer Therapeutics and Prevention Member, Bioinformatics Core Steering committee JUNIOR FACULTY MENTORED Andrei Bakin, Ph.D. Assistant Member Dominic Smiraglia, Ph.D. Assistant Member CANCER CENTER SUPPORT GRANT PROGRAM PARTICIPATION Cell Stress and Biophysical Therapies Program EDITORIAL RESPONSIBILITIES 2010 Member, Editorial Board, Breast Cancer: Targets and Therapy 2009 Member, Editorial Board, Journal of Oncology


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2007 Member, Editorial Board, Cancer Genomics and Proteomics 2006 Guest Editor for “Advances in MicroArray Technology”, Cancer

Genomics and Proteomics journal (Invited but declined) 2006-2008 Member, Editorial Board, Nanomedicine: Nanotechnology, Biology and Medicine 2005 Guest Editor, Nanotechnology In Cancer Detection and Treatment, Technology in Cancer Research and Treatment 2004-Present Member, Editorial Board, Technology in Cancer Research and Treatment 2002-Present Member, Editorial Board, Molecular Cancer 2001-Present Member, Editorial Board, Cancer Biology & Therapy 2002-2008 Member, Editorial Board, FEMS Yeast Research 2000-Present Founding Editor-in-Chief, Mitochondrion 2017-Present Founding Editor-in-Chief, Cancer Health Disparities JOURNAL PEER REVIEW ACTIVITIES American Journal of Human Genetics, American Journal of Physiology, Biotechniques, Blood, Cancer Letters, Cancer Research, Carcinogenesis, Clinical Cancer Research, Clinical Chemistry, Critical Reviews in Therapeutics Drug Carrier Systems, Current Genetics, FASEB Journal, FEMS Yeast Research, Free Radical Biology and Medicine, Antioxidant and Redox Siganling, Genetics, Mitochondrion, Mutagenesis, Oncogene, Pediatric Research, Pharmacogenomics, PloS One, PloS Genetics, Epigenetics, Proceeding of National Academy of Sciences (PNAS), Nature Communication, Nature. NATIONAL AND INTERNATIONAL COMMITTEES AND ADVISORY BOARDS Member Search Committee for Researchers, Institute of Molecular Pathology and Immunology of the University of Porto, Portugal. Member, Scientific Advisory Board, Nyhan Center for Mitochondria Research and Medicine planned at Stanford University, Stanford, CA Advisor, Methodology Section, Mitochondrial Proteomics Workshop, National Institute of Standard and Technology (NIST), Gaithersburg, MD North American Councilor, Mitochondrial Medicine Society, San Diego, CA Member, Site Visit Panel to review a program project application “Oxidative stress, mitochondrial dysfunction and aging” at the University of Texas Medical Branch, Galveston. Member, Panel to review meeting grant application by Environmental Mutagen Society, Reston, VA. Member, Oversight Committee, Research Expansion Plan, United Mitochondrial Disease Foundation


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Member, Scientific Advisory Board, United Mitochondrial Disease Foundation Member, Laboratory Task Force for Molecular/Genetic Detection of Mitochondrial Dysfunction in Human Tissues Member, International Advisory Board, Asian Society for Mitochondrial Research and Medicine, Seoul, Korea Member, International Advisory Board, Mitochondrial Physiology Society, Insbruck, Austria Member, Advisory Board, MitoSchool, University of Roskilde, Roskilde, Denmark NATIONAL AND INTERNATIONAL CONFERENCE ORGANIZING COMMITTEE Member, Organizing Committee, Mitochondrial Biology and Medicine – Meeting of the Society of Mitochondria Research and Medicine, Central Drug Research Institute, Lucknow, Nov 28-30, 2018. Member, Organizing Committee, Mitochondrial Medicine 2018 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Nashville, TN, June 27-30. Member, Organizing Committee, Mitochondrial Mini Symposium of the Indian Scoeciety for Mitochondrial Research and Medicine, Center for Cellular and Molecular Biology, March 1, 2018. Member, Organizing Committee, Mitochondrial Medicine 2017 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Washington DC, June 28-July 1. Member, Organizing Committee, Regional Mitochondrial Medicine Symposium, Foundation For Mitochondrial Medicine, Birmingham, Alabama, April 7-8, 2017. Member, Organizing Committee, International Conference on Mitochondria in Health and Disease, Jawaherlal Nehru University, New Delhi, Feb 10-11, 2017. Member, Organizing Committee, Mitochondrial Medicine 2016 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Seattle, USA, June 14-18, 2016. Chair/Organizer, Minisymposium on Mitochondria, Metabolism and Epigenetics, Doubletree, Birmingham, October 3, 2015. Member, Organizing Committee, Mitochondrial Medicine 2015 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Washington DC, USA, June 15-18, 2015.


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Member, Organizing Committee, Mitochondrial Medicine 2014 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Pittsburgh, USA, June 4-7, 2014. Member, Organizing Committee, Mitochondrial Medicine 2013 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, San Diego, USA, June 16-19, 2013. Member, Organizing Committee, Mitochondria in Health and Disease – Meeting of Society for Mitochondrial Research and Medicine, Bangaluru, India, Dec 19-20th, 2013. Co- Organizer, 3rd International Conference on Stem Cells and Cancer (ICSCC-2012), October 25-27, 2012. New Delhi Member, Organizing Committee, Mitochondria in Health and Disease – Meeting of Society for Mitochondrial Research and Medicine, Bangaluru, India, Nov2-3, 2012. Member, Organizing Committee, Mitochondrial Medicine 2012 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Washington, DC, USA, June 13-16, 2012. Member, Organizing Committee, Mitochondrial Medicine 2011 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Chicago, USA, June 24-27, 2009. Co-Chair, International Conference of Mitochondria Research and Medicine, Shri Mata Vaisno Devi University, Katra, Jammu and Kashmir, India, Nov 12-13, 2010. Member, Organizing Committee, Mitochondrial Medicine 2010 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Glendale, AZ, USA, June 24-27, 2009. Member, Organizing Committee, Mitochondrial Medicine 2009 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Washington DC, USA, June 24-27, 2009. Member, Organizing Committee, 2nd Indo-US workshop on Mitochondria Research and Medicine, Manipal University, Manipal, India, Nov 12-14, 2008 Member, Organizing Committee, Mitochondrial Medicine 2008 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society Indianapolis, USA, June 25-29, 2008. Co-Chair, Indo-US workshop on Mitochondria Research and Medicine, Center for Cellular and Molecular Biology, Hyderabad, India, Jan 22-24, 2007


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Member, Organizing Committee, Mitochondrial Medicine 2007 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, San Diego, USA, June 13-17. Chair, NCI workshop on Mitochondrial DNA and Epidemiology of Cancer, September 2006 – Bethesda, Maryland Member, Organizing Committee, Mitochondrial Medicine 2006 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Atlanta, USA Member, Organizing Committee, Mitochondrial Medicine 2005 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, St Louis, USA Member, Organizing Committee, Yeast Apoptosis 2005, Miami, Florida, USA Member, Organizing Committee, Mitochondrial Medicine 2004 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, Pittsburgh, USA Member, Organizing Committee, Mitochondrial Medicine 2003 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, San Diego, USA Member, Organizing Committee, Mitochondria 2002, Moscow, Russia Member, Organizing Committee, Symposium – Yeast as a model for mitochondria related human diseases, Prague, Czech Republic Member, Organizing Committee, Workshop on Mitochondrial Laboratory Techniques Standardization, Dallas, Texas USA Member, Organizing Committee, Mitochondrial Medicine 2001 – Meeting of United Mitochondrial Research Foundation and the Mitochondria Research Society, San Diego, USA GRANT REVIEWER AD HOC MEMBER ZRG1 GGG-D (90) S Genes, Genomics and Genetics Special Emphasis Panel, 2018 SIEE Adhoc Member, Systemic Injury by Environmental Exposure, 2018 ZCA1 SRB-1 (O1) S NCI Clinical and Translational Exploratory/Developmental Studies Grant Reviewer, French National Cancer Institute (INCa), 2018 ZRG1 CB-D (55) Par Panel: Inter-organelle Communication in Cancer, 2018 ZCA1 RTRB-U (M2) S SEP-5A: NCI Clinical and Translational Exploratory/Developmental Studies, 2018 ZRG1 OBT-B (55) PAR Panel: Basic Research in Cancer Health Disparities/Diversity, 2017 Nathan Shock Aging Center, University of Texas Health Science Center, San Antonio, 2017.


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NCI R21 and R03 SEP-8ZCA1 TCRB-D (M3), 2017 NICHD Genomic Clinical Variant Expert Curation Panels Review/U24, 2017 Therapeutic approach to genetic diseases (TAG) study section, 2017 NIH, SEP ZRGG1 GGG-B 50, 2017 Member Board of Scientific Councilor, NIEHS, review of the Genome Integrity and Structural Biology Laboratory (GISBL), 2017 DOD Gulf War Illness Research Program, 2017 (declined) NCI, Cancer Drug Development & Therapeutics study section, 2017 (declined). National Science Center, Poland, 2017 ZCA1 SRB-C (J2) NCI Provocative Question #5, 2016 DOD Mitochondrial Disease Expert Panel, 2016 NIH/ Emphasis study section panel NCO R03 SEP ZCA1SRB1, 2015 NIH/XNDA June 2014 NIH/ Emphasis study section panel ZCA1SRB1O1 NIH/SBIR CDDT Emphasis study section panel ZRG1 OTC T 10 B, March 12-13, 2012. Reviewer, The French National Research Agency, March 2012 (declined) NIH / NIAAA - Special Emphasis Panel ZAA1 JJ (01) Mechanism of Alcohol-Induced Organ Damage, April 20, 2011. NIH, Special Emphasis Panel ZRG1 GGG-N (02)S, Genetic Disease Therapy, June 27th, 2011. NIH, Special Emphasis Panel ZRG1 GGG-T (02)M, Molecular Genetics, June 20th, 2011. Italian Association for Cancer Research, Italy, 2011 Medical Research Council, England, 2011 NIH, Special Emphasis Panel ZRG1 GGG-F (55), May 25th, 2010 Department of Defense, Breast Cancer Program, Pre-doc and Post-Doc Fellowship Panel. May 3-5, 2009 National Institutes of Health, Special Emphasis Panel, Transformative RO1 on Mitochondria, May 15, 2009. National Institutes of Health, Special Emphasis Panel ZRG1 OBT-A (96), July 23-24th, 2009. National Institutes of Health, Special Emphasis Panel, The role of mitochondria in alcohol-induced tissue injury, March 17-18, 2008, ZAA1 JJ (17) National Institutes of Health, Genetics of Health & Disease National Institutes of Health, Cancer Etiology Study Section National Institutes of Health, Radiation Research Study Section National Institutes of Health, Basic Mechanism of Cancer Therapeutics Study Section National Institutes of Health, Special Emphasis Panel/ 2004/10 ZRG1 ONC-B (05) Komen Breast Cancer Foundation National Research Council, Canada United States-Israel Binational Science Foundation, Israel Wellcome Trust, England U.S. Department of State, Radiation Research U.S. National Science Foundation U.S. Department of Energy, Radiation Research (declined) Le Centre de Génétique Moléculaire et Cellulaire, CNRS, Lyon, France (declined) Medical Research Council, London, United Kingdom (declined) Biomedical Research Council, Singapore (declined) Department of Defense Breast Cancer Research Program


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Cancer Research UK, London, United Kingdom (Declined) CHARTER MEMBER 2009-2013 Cancer Etiology Study Section, National Institute of Health, USA REVIEWER BOOK PROPOSALS Mitochondria and Heart, Kluver Academic Publishers, New York, NY Cellular Respiration and Carcinogenesis, Springer, New York, NY Mitochondrial Case Study, Academic Press/Elsevier, Waltham, MA (declined) PROFESSIONAL MEMBERSHIPS American Association for Cancer Research American Association for Advancement of Science Society for Free Radical Biology and Medicine-USA Indian Science Congress Association (Life Member) Indian Association for Cancer Research (Life Member) Indian Association for Human Genetics (Life Member) Society for Free Radical Research-India (Life Member) American Society for Human Genetics NATIONAL AND INTERNATIONAL INVITED SEMINARS/LECTURES/PRESENTATIONS 2019 Intervention in Aging, Bahamas. 2019 Science of Aging, Monte Carlo, Monaco 2019 Mitochondrial Medicine, Washington DC 2019 Science of Aging, Monte Carlo, Monaco 2019 Skin Aging and Challenges, Porto, Portugal (declined) 2018 Speaker, Mitochondrial Biology and Medicine meeting of the Society for

Mitochondrial Research and Medicine, India. 2018 Session Chair, Mitochondrial Biology and Medicine meeting of the Society

for Mitochondrial Research and Medicine, India. 2018 Plenary speaker, Health Disparities Conference, Honolulu, Hawaii, USA 2018 Speaker, International Conference on Subcellular Organelles, Shanghai,

China 2018 Session Chair, International Conference on Subcellular Organelles,

Shanghai, China 2018 Speaker, National Cancer Center, Tokyo, Japan 2018 Speaker, European Bioenergetics Conference, Budapest, Hungary 2018 Plenary speaker, Health Disparities Conference, Honolulu, Hawaii, USA 2018 Speaker, University of Hawaii Cancer Center, Honolulu, Hawaii, USA 2018 Speaker, International Cell Biology Cancer Congress, Hyderabad, India 2018 Speaker, Mini-Symposium on Mitochondria in Health, Center for Cellular

and Molecular Biology, Hyderabad, India. 2018 Speaker, University of Hawaii Cancer Center, Honolulu, Hawaii, USA 2018 Speaker, Chiba Medical School, Chiba, Japan 2018 Speaker, CCTS, UAB, Birmingham, Alabama, USA


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2017 Speaker, Stephenson Cancer Center, University of Oklahoma, Oklahoma City, OK, USA

2017 Speaker, CNSE Colloquium, SUNY Polytechnic Institute, Albany, Alabama, USA

2017 Speaker, Regional Mitochondrial Medicine Symposium, Birmingham, Alabama, USA

2017 Speaker, Society for Mitochondrial Research and Medicine, India, New Delhi, India.

2016 Distinguish Seminar Speaker, Georgia Cancer Center, Augusta, Georgia. 2016 Speaker, International Conference on Nutraceuticals in Chronic Disease,

Kochi, India. 2016 Jisnuson Svasti Award/Plenary Lecture, International Union of Biochemistry

and Molecular Biology, Hyderabad, India 2016 Speaker, Society for Mitochondrial Research and Medicine, India, Madurai,

India. 2016 Mitochondrial Medicine Symposium, Seattle, Oregon. 2016 Speaker, International Conference on Genome Medicine, Taipei, Taiwan 2015 Speaker, Minisymposium on Mitochondria, Metabolism and Epigenetics,

Doubletree, Birmingham. 2015 Speaker, Asian Society for Mitochondrial Research and Medicine, Hangzhou,

China (declined) 2015 Speaker, Inauguration Lecture of the Douglas C Wallace Center for

Mitochondrial Medicine, Beijing, China (declined) 2015 Speaker, Society for Mitochondrial Research and Medicine, India meeting,

Madurai, India. 2015 Plenary Lecture, International Union of Biochemistry and Molecular Biology,

Hyderabad, India 2015 Department of Hematology and Oncology, UAB School of Medicine,

Birmingham. 2015 Mitochondrial Medicine Symposium, Sheraton, Washington DC 2015 Keynote lecture, Targeting mitochondrial dysfunction and toxicity

symposium, Boston, MA, USA. 2015 Eastern Virginia Medical School, Norfolk, Virginia 2014 International Conference on Response to Drugs, Central Drug Research

Institute, Lucknow, India 2014 International Conference on Molecules to Mitochondria, Manipal University,

Manipal, India. 2014 SAARC (South Asian Association for Regional Cooperation) Countries

Oncology Conference, Leela Palace, Delhi, India 2014 Southern Research Institute, Birmingham, Alabama 2013 International Conference on Targeting Mitochondria for Therapy, Berlin,

Germany 2013 EMBO Workshop on Mitochondria and Cancer, Stockholm, Sweden 2013 Seminar, Institute for Healthy Aging, University of Copenhagen, Copenhagen,

Denmark


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2013 International Congress on Plant Mitochondria, Rosario, Santa Fe, Argentina (declined)

2013 International Symposium: Infection and Cancer, Indian Association of Cancer Research, Delhi.

2012 Russian conference on Problems of cell energetic disorders (mitochondrial pathology), Moscow, Russia (declined)

2012 Speaker, 4th Genome Dynamics in Neuroscience, University of Oslo Centre of Molecular Biology and Neuroscience, Oslo, Norway

2012 Conference on Mitochondria in Biology and Medicine, Gandhi Nager, India (declined).

2012 International Conference on Stem Cells and Cancer, Delhi, India (declined). 2012 Speaker, Outstanding Achievement Award Lecture, Society of American Asian

in Cancer Research, Chicago, IL. 2012 Speaker, International Conference on Mitochondria and Metabolism, Porto.

Portugal. 2012 Speaker, Health Disparity Research Symposium, UAB School of Medicine,

Birmingham, AL. 2012 Speaker, Lung Cancer Working Group, UAB Comprehensive Cancer Center,

Birmingham, AL. 2012 Key Note Speaker, Scientific Meeting of the Department of Microbiology,

Biochemistry and Immunology, Morehouse Medical School, Atlanta. 2011 Speaker at UCLA Molecular Biology Institute, University of California, Los

Angeles. 2011 Speaker at Meeting of the Japanese Society for Mitochondrial Biology and

Medicine, Kagoshima (invitation declined) 2011 Speaker, NIH Cancer Health Disparity Research Symposium, Bethesda,

Maryland.2011 2011 Speaker, Society for Free Radical Biology and Medicine meeting, Atlanta. 2011 Speaker, Conference on Targeting Mitochondria, Berlin, Germany. 2011 Speaker, Conference Mitochondria, Apoptosis and Cancer, Singapore

(invitation declined). 2011 International Symposium on Mitochondrial Biology and Medicine, Pusan,

Korea (Invitation declined). 2011 UAB Comprehensive Cancer Center, NIH Breast Cancer Spore presentation. 2011 Seminar, Center for Mitochondrial and Molecular Medicine, Wayne State

University, Detroit. 2011 Speaker, International Conference on Advances in Cancer Research,

Central University of Gujrat, Gandhinagar, Gujrat, India 2010 Seminar, Central University of Gujrat, Gandhinagar, Gujrat, India 2010 Session Chair and Speaker, International Conference on Mitochondrial

Research and Medicine, Shri Mata Vaisno Devi University, Katra, Jammu, India.

2010 Speaker, IARU Congress, University of Copenhagen, Copenhagen, Denmark 2010 Speaker, 16th European Bioenergetics Conference - Warsaw, Poland. 2010 Speaker, 10th Conference of the Japanese Society pf Mitochondrial Research

and Medicine, Fukuoka City, Japan (Declined)


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2010 Speaker, International Conference on Mitochondria Research and Medicine, Sri Mata Vaisno Devi University, Katra, J&K, India.

2010 Speaker, Department of Pharmacology and Toxicology, University of Missouri, Kansas City, MO

2010 6th Conference on Metal Toxicity and Carcinogenesis, Lexington, KY (Declined)

2010 Speaker, UAB Comprehensive Cancer Center, University of Alabama, Birmingham, AL

2010 Speaker, MitoSchool Workshop, Aarhus, Denmark. 2010 Speaker, Bergen Cancer Conference, Loen, Norway. 2010 Speaker, Department of Biomedicine, University of Bergen, Bergen, Norway. 2010 Speaker, Markey Cancer Center, University of Kentucky, Lexington, KY 2010 Speaker, Symposium Indian Society of Human Genetics, Sanjay Gandhi

Postgraduate Medical Institute, Lucknow, India 2010 Speaker, Symposium Breast Cancer Foundation of India, King George Medical

University, Lucknow, India 2010 Speaker, Symposium on mitochondrial DNA dynamics in aging, Aarhus,

Denmark. 2009 Speaker, EMBO Meeting on Mitochondria, Apoptosis and Cancer, Prague,

Czech Republic. 2009 3rd Mitochondrial Biomedicine Conference, Wenzhou Medical College, China 2009 Key Note Speaker, Mitochondria Summer School, Roskilde University,

Denmark (declined) 2009 Speaker, Mitochondrial Medicine Conference, Washington DC 2009 Speaker, University of New Mexico Cancer Center, University of New Mexico,

Albuquerque, NM 2009 Speaker, Holden Comprehensive Cancer Center, University of Iowa, Iowa

City, IA. 2008 Speaker, Alexander Hollaender Workshop, Indian Institute of Toxicology,

Lucknow, India 2008 Speaker, Alexander Hollaender Meeting on Genetic Toxicology, Kolkata, India 2008 Session Chair, Genomics and Proteomics of Arsenic Induced cancer, Alexander Hollaender Meeting on Genetic Toxicology, Kolkata, India 2008 Key Note Speaker, 2nd Indo-US meeting on Mitochondrial Research and

Medicine, Manipal, India. 2008 Session Chair, Mitochondria and Cancer, 2nd Indo-US meeting on

Mitochondrial Research and Medicine, Manipal, India. 2008 Key Note Speaker, 60th Anniversary of Korean Society of Biochemistry and

Medical Microbiology, Seoul, Korea 2008 Seminar, Department of Genetics, UAB Comprehensive Cancer Center,

University of Alabama, Birmingham, AL 2008 Speaker, 5th Conference on Metal Toxicity and Carcinogenesis, Morgantown,

WV, USA 2008 Speaker, Asian Society for Mitochondria Research and Medicine Meeting,

Tianjin, China (invited but declined). 2008 Speaker, Arsenic 2008 International Congress, Valencia, Spain


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2008 Seminar, Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal

2008 Elsevier Editor’s Conference, April 18-19, Vancouver, Canada 2008 Speaker, 13th World Congress on Advances in Oncology, Oct 9-11, Crete,

Greece (invitation declined). 2008 Seminar, Department of Molecular Oncogenesis, University of Cincinnati,

Ohio. 2008 Session Chair and Speaker, Mitochondria Mini Symposium, National Institute

of Health, Bethesda, Maryland. 2007 MACKAY SYMPOSIUM 2007, Mackay Memorial Hospital, Taipei, Taiwan 2007 Speaker, Ageing after 50 years of the free radical hypothesis – a tribute to

Denham Harman, Porto, Portugal (Invitation declined) 2007 Seminar, Center for Cancer Genomics, University at Albany, Albany, New

York. 2007 Speaker, International Conference on Chromosome to Genome, Center for

Cellular and Molecular Biology, Hyderabad, India, July 2-5th, 2007. 2007 Seminar, Sidney Kimmel Cancer Center, Thomas Jefferson University College

of Medicine, Philadelphia, PA. 2007 Seminar, Department of Pathology, University of Illinois at Chicago, Illniois. 2007 Seminar, Sidney Kimmel Cancer Center, San Diego, CA. 2007 Seminar, Department of Molecular Genetics and Biochemistry, University of

Ohio, Columbus, Ohio. 2007 Seminar, Department of Pathology, University of South Carolina, Columbia,

SC. 2007 Speaker and Organizer, Indo-US workshop on Mitochondrial Research and

Medicine, Center for Cellular and Molecular Biology, Hyderabad, India, Jan 22-24, 2007.

2006 Symposium Chair: Mitochondrial Nanomedicine, The Second Annual Meeting of American Academy of Nanomedicine, Washington DC, USA September 9-10, 2006 (Invited but declined)

2006 Speaker, 5th European Congress of Biogerontology, Istanbul, Turkey 2006 Speaker and Chair, International Conference on Mitochondria Medicine,

Wenzhou, China 2006 Speaker, 13th Annual Meeting of the Society of Free Radical Biology and

Medicine, Denver, Colorado, USA (Invited but declined) 2006 Speaker and Chair, EMBO Workshop on Evolution and Disease, Center for

Cellular and Molecular Biology, Hyderabad, India. 2006 New York State Biotechnology Association, Invitation to participate in

Upstate Biotechnology Roundtable Discussion, Invited but declined. 2006 Elsevier Editor’s Conference, Montreal, Canada, Invited but declined 2006 Seminar, Molecular Signaling Group, Department of Biochemistry, School of

Medicine and Biomedical Sciences, SUNY-Buffalo 2006 Speaker, Mitochondria 2006, Meeting of United Mitochondrial Disease

Foundation, and the Mitochondria Research Society, Atlanta, USA 2006 Speaker, Arsenic 2006, Mexico City, Mexico. Invited but declined 2006 Seminar, Burke-Cornell College of Medicine, White Plaines, NY


17

2005 Speaker, International Conference on Antioxidant and Free Radicals in Health, January 10-12, Bangalore, India

2005 Session Chair, Oxidative Stress and Cancer, International Conference on Antioxidant and Free Radicals in Health, January 10-12, Bangalore, India 2005 Seminar, Center for Cellular and Molecular Biology, January 14, Hyderabad, India 2005 Speaker, Mitochondria 2005 Symposium, Meeting of United Mitochondrial

Disease Foundation and the Mitochondria Research Society, St Louis, USA 2005 Speaker, Workshop on Nuclear and Mitochondrial DNA Repair in Cancer and

Aging, April 29-30, Copenhagen, Denmark 2005 Speaker, 11th International Gerontology Society Meeting, August 12-16,

Aarhus, Denmark 2005 Speaker, NIH/Howard Hughes Workshop on Mitochondrial DNA transactions

in Health & Diseases, Howard Hughes Medical Institute, Bethesda, MD, USA 2005 Speaker, Mitochondrial Physiology 2005, The Many Faces and Functions of

an Organelle, September 16-20, - Schröcken, Vorarlberg, Austria 2005 Speaker, 3rd International Conference on Tumor Metabolism, October 19-23,

Louisville, KY, USA 2005 Speaker, Conference on Bio Micro and Nanotechnology and Medicine,

November 3-4, Albuquerque, NM. 2005 Special Lecture, International Conference on Mitochondria and Life, December 15-17, Tokyo, Japan. 2005 Session Chair, International Conference on Mitochondria and Life, December

15-17, Tokyo, Japan. 2004 Seminar, Cancer Chemoprevention and Chemotherapy Program, Roswell

Park Cancer Institute, Buffalo, NY, USA 2004 Speaker, Asian Society of Mitochondrial Research and Medicine, Taipei,

Taiwan. Invited but declined. 2004 Speaker, Symposium on Single-Molecule Bioanalysis and Nano-Biodevice

(SMBN 2004) Takamatsu City, Japan. Invited but declined. 2004 Speaker, Symposium on Mitochondria and Pathogenesis EUROMIT6,

University Medical Centre Nijmegen, the Netherlands. Invited but declined. 2004 Seminar, Mitochondria 2004 Symposium, The meeting of United

Mitochondrial Disease Foundation and the Mitochondria Research Society, August 4-6, Pittsburgh, PA.

2004 Speaker, Symposium on Mitochondria and Cancer, October 1-3, 2004, Glasgow, Scotland.

2004 Speaker, Symposium on Cross-Talk between Nucleus and Organelles, September 15-18, Naples, Italy.

2003 Session Chair, Asian Society for Mitochondria Research and Medicine, Seoul, South Korea.

2003 Special Lecture, Asian Society for Mitochondria Research and Medicine, Seoul, South Korea.

2003 Seminar, Kagoshima University, Kagoshima, Japan. 2003 Seminar, Kurume University, Kurume, Japan.


18

2003 Seminar, National Institute of Radiological Sciences, Chiba, Japan. 2003 Seminar, Mitochondria 2003 Symposium, June 11-14, San Diego, CA, USA 2003 Speaker, 10th Congress, International Association of Biomedical Gerontology,

September 19-23, Cambridge University, Cambridge, England. 2003 Speaker, 2nd International Meeting on Yeast Apoptosis, September 17-20,

Cancer Research Institute, Bratislava, Slovak Republic. 2003 Seminar, DNA damage and repair group, Roswell Park Cancer Institute,

Buffalo, NY. 2003 Seminar, Department of Cellular Stress Biology, Roswell Park Cancer

Institute, Buffalo, NY. 2003 Presentation, Department of Cancer Genetics Retreat, Roswell Park Cancer

Institute, Buffalo, NY. 2003 Speaker, Mitochondrial proteomics workshop, National Institute of Standard

and Technology, Gaithersburg, MD. 2002 Speaker, Symposium on Mechanisms of Mitochondrial Pathogenesis, Society

of Veterinary Pathologist, Salt Lake City, Utah. 2002 Session Chair, Symposium on mitochondrial proteomics, National Institute of Standard and Technology, Gaithersburg, MD 2002 Speaker, Society for Women’s Health Research, Sex and Gene Expression III.

Invited but Declined 2002 Session Chair, Symposium on Mechanism of Mitochonchondrial Function and

Disease, Dallas, TX 2002 Speaker, Symposium on Oxidative Stress: Molecular Mechanisms, Diseases

and Therapeutics, National Institute of Health, Bethesda, MD. 2002 Speaker, Key Stone Symposium, Copper Mountain, CO. 2002 Seminar, Free Radical and Radiation Biology Program, Iowa School of

Medicine, Iowa City, IA. 2002 Seminar, Department of Radiation Oncology, Wake Forest University School

of Medicine, Winston Salem, NC. 2002 Seminar, Department of Pharmacology and Toxicology, School of Veterinary

Medicine, Louisiana State University, Baton Rouge, LA. 2002 Seminar, Eppley Institute for Cancer Research, University of Omaha School of

Medicine, Omaha, NE. 2002 Seminar, Department of Pharmacology and Toxicology, Virginia

Commonwealth University School of Medicine, Richmond, VA. 2002 Seminar, James Graham Brown Cancer Center, University of Louisville School

of Medicine, Louisville, KY. 2002 Seminar, Lucille P. Markey Cancer Center, University of Kentucky School of

Medicine, Lexington, KY. 2002 Seminar, Department of Pharmacology Ohio State University School of

Medicine, Columbus, OH. 2002 Seminar, Institute of Environmental Health Sciences, Wayne State University,

Detroit, MI. 2002 Seminar, Department of Cancer Genetics, Roswell Park Cancer Institute,

Buffalo, NY.


19

2001 Speaker, Mitochondria 2001, Meeting of the United Mitochondrial Disease Foundation and the Mitochondria Research Society, San Diego.

2001 Welcome Address, Conference: Mitochondria 2001, Meeting of the United Mitochondrial Disease Foundation and the Mitochondria Research Society, San Diego, CA

2001 Speaker, Society for Women’s Health Research, Conference on Sex and Gene Expression. Winston Salem, NC.

2001 Seminar, Department of Anatomy and Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD.

2001 Seminar, Division of Toxicology, Johns Hopkins School of Public Health, Baltimore, MD.

2001 Speaker, Second International Conference on Oxidative Stress and Aging: Technologies for Assessment and Intervention Strategies. Invited to host a “ask the expert” roundtable discussion. Declined

2001 Speaker, Radiation Research Meeting, San Juan, Puerto Rico. 2001 Speaker, Center for Biomarker Discovery, Johns Hopkins Oncology Center. 2001 Speaker, Symposium Yeast as a Model for Mitochondria Related Human

Disorders. Prague, Czech Republic. 2001 Seminar, Department of Environmental Health, Johns Hopkins School of

Public Health, Baltimore, MD. 2000 Seminar, University of Maryland Oncology Center, Baltimore, MD. 2000 Speaker, NIH Symposium Mitochondria: Interaction of Two genomes.,

Bethesda. MD. 2000 Seminar, Johns Hopkins Oncology Center, Breast Cancer Research Program.

Mitochondria and Breast Cancer 2000 Session Chair, Symposium Yeast as a Model for Mitochondria Related Human

Disorders. Prague, Czech Republic. 1999 Speaker, Symposium “The New Biology of Aging” University of Kansas. Mitochondrial DNA Repair and Aging 1999 Seminar, Division of Toxicology, Johns Hopkins School of Public Health,

Baltimore, MD. 1999 Seminar, Breast Cancer Research Program, Johns Hopkins Oncology Center,

Baltimore, MD. 1999 Biology of Cancer Lecture, Johns Hopkins Oncology Center, Baltimore, MD 1999 Seminar, Department of Biochemistry and Molecular Biology, University of

Maryland, Baltimore, MD. 1998 Seminar, Bionumeric Pharmaceutical, Dallas, TX 1998 Speaker, IV International Conference on Geriatric Oncology, Rome, Italy 1998 Seminar, Division of Radiation Oncology, Johns Hopkins Oncology Center,

Baltimore, MD. 1998 Seminar, Division of Toxicology, Johns Hopkins School of Public Health, Baltimore, MD. 1998 Presentation to Stewart Trustees, Johns Hopkins Oncology Center, Baltimore,

MD. 1998 Speaker, Asia Pacific Cancer Congress, Madras, India 1997 Seminar, Department of Biosciences, Drexel University, Philadelphia, PA.


20

1997 Seminar, breast Cancer Research Program. Johns Hopkins Oncology Center, Baltimore, MD.

1996 Seminar, Johns Hopkins Oncology Center, Division of Radiation Oncology, Baltimore, MD

1996 Seminar, Division of Toxicology, Johns Hopkins School of Public Health, Baltimore, MD.

1995 Seminar, Oregon Health Sciences University, Center for Research on Environmental Toxicology, Portland, OR.

1995 Seminar, Division of Radiation Oncology. Johns Hopkins Oncology Center, Baltimore, MD.

MEDIA/PRESS INTERVIEWS 2015 PBS News Hour

http://www.pbs.org/newshour/updates/term-three-person-baby-makes- doctors-wince/

2015 Interview SHAPE magazine 2011 UAB School of Medicine magazine. 2008 Environmental Health Perspective. 2007 PROTO, Magazine of the Massachusetts General Hospital, Harvard Medical School. 2006 Power Games, Nature 443: 901 (Oct 26th, 2006) 2006 Story: Can our cells heal each other? New Scientist, January 28 2006 Microbe, The Magazine of American Society for Microbiology, June 2006 2002 Associated Press, Stories: Science may realize couch potato’s dream: Toned body with no huffing and puffing, MSNBC Researchers: Pill may some day replace exercise, CNN 2001 BioMedNet, Story: Mitochondrial Manipulation of Human Germ Line. 2001 Telemundo Radio, Washington, Story: Genetically Engineered Baby, One Father and Two Mothers COMMUNITY SERVICE 2001-Present Appointed as Honorary Chairman of the Business Advisory Council by the

Majority Whip of the House (United States Congress) to help represent the health issues and provide leadership in small business related to mitochondrial health.

2000-Present Help patients, their families and students from around the world in

understanding the role of mitochondria in pathogenesis of human diseases. Answer questions and provide guidance.

PEER REVIEWED RESEARCH ARTICLES 88. Bajpai P, Koc E, Sonpavde G, Singh R, Singh KK. Mitochondrial import and

mitochondrial function of Androgen Receptor, Journal of Biological Chemistry, 294(16):6621-6634, 2019.

http://www.pbs.org/newshour/updates/term-three-person-baby-makes-


21

87. Singh B, Schoeb RT, Bajpai P, Slominski AT, Singh KK. Reversing Wrinkled Skin and Hair

Loss in Mice by Restoring Mitochondrial Function, Cell death and Disease, 9(7):735, 2018 86. Carden T, Singh B, Mooga V, Bajpai P, Singh KK. Epigenetic modification of

miR-663 controls mitochondria-to-nucleus retrograde signaling and tumor progression. Journal of Biological Chemistry 292(50):20694-20706, 2017. 85. Choudhury AR, Singh KK. Mitochondrial determinants of cancer health disparities. Seminars in Cancer Biology. 2017 pii: S1044-579X(17)30122-0. doi: 10.1016/j.semcancer.2017.05.001, 2017. 84. Singh B, Modica-Napolitano JS, Singh KK. Defining the momiome: Promiscuous information transfer by mobile mitochondria and the mitochondrial genome.

Seminars in Cancer Biology. pii: S1044-579X(17)30127-X. doi: 10.1016/j.semcancer.2017.05.004, 2017. 83. Singh KK, Choudhury AR, Tiwari HK. Numtogenesis as novel cancer mechanism,

Seminar in Cancer Biology, pii: S1044-579X(17)30122-0. doi: 10.1016/j.semcancer.2017.05.001

82. Koo DH, Singh B, Jiang J, Friebe B, Gill BS, Chastain PD, Manne U, Tiwari HK, Singh

KK. Single molecule mtDNA fiber FISH for analyzing numtogenesis. Analytical Biochemistry. pii: S0003-2697(17)30131-8. doi: 10.1016/j.ab.2017.03.015, 2017.

81. Srinivasainagendra V, Sandel MV, Singh B, Sundaresan A; Mooga VP, Tiwari HK,

Singh KK. Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma. Genome Medicine, 9(1):31. doi: 10.1186/s13073-017-0420-6, 2017.

80. Singh B, Kulawiec M, Owens KM, Singh A, Singh KK. Sustained early disruption of mitochondrial function contributes to arsenic-induced prostate tumorigenesis. Biochemistry 81(10):1089-1100, 2016.

79. Singh B, Owens KM, Bajpai P, Desouki MM, Srinivasasainagendra V, Tiwari HK, Singh

KK. Mitochondrial DNA polymerase POLG1 disease mutations and germline variants promote tumorigenic properties. PLoS One. 10(10):e0139846, 2015.

78. Singh B, Li X, Owens KM, Vanniarajan A, Liang P, Singh KK. Human REV3 DNA

polymerase zeta Localizes to mitochondria and protects the mitochondrial genome. PLoS One. 10(10):e0140409, 2015.

77. Ghosh S, Singh KK, Sengupta S, Scaria V. Mitoepigenetics: The different shades of

grey. Mitochondrion. 25:60-6, 2015.


22

76. Kabekkodu SP, Chakrabarty S, Shukla V, Varghese VK, Singh KK, Thangaraj K, Satyamoorthy K. Mitochondrial biology: From molecules to diseases. Mitochondrion.

24:93-8, 2015 75. Zhang H, Singh KK. Global genetic determinants of mitochondrial DNA copy number.

PLoS One. 9(8):e105242. doi: 10.1371/journal.pone.0105242, 2014. 74. Nunes JB, Peixoto J, Soares P, Maximo V, Carvalho S, Pinho S, Vieira A, Paredes J,

Rego AC, Ferreira IL, Gomez-Lazaro M, Sobrinho-Simoes M, Singh KK, Lima J. OXPHOS dysfunction regulates integrin-1 modifications and enhances cell motility and migration. Hum Mol Genet. 24(7):1977-90, 2015

73. Donthamsetty S, Brahmbhatt M, Pannu V, Rida PC, Ramarathinam S, Ogden A, Cheng A, Singh KK*, Aneja R. Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis. Cell Cycle. 13(13), 2014. *Corresponding author

72. Rodell A, Rasmussen LJ, Bergersen LH, Singh KK, Gjedde A. Natural selection of

mitochondria during somatic lifetime promotes healthy aging. Front Neuroenergetics. 5:7. doi: 10.3389/fnene.2013.00007, 2013

71. Bhattacharjee P, Chatterjee D, Singh KK, Giri AK. Systems biology approaches to

evaluate arsenic toxicity and carcinogenicity: an overview. Int J Hyg Environ Health. 216(5):574-86, 2013. 70. Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR,

Segal BH. NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury. J Immunol. 15;190(4):1714-24, 2013

69. Desler C, Hansen TL, Frederiksen JB, Marcker ML, Singh KK, Juel Rasmussen L. Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging? J Aging Res. 2012:192503, 2012. 68. Minocherhomji S, Tollefsbol TO, Singh KK. Mitochondrial regulation of epigenetics

and its role in human diseases. Epigenetics. 7(4):326-34, 2012. 67. Azrak S, Ayyasamy V, Zirpoli G, Ambrosone C, Bandera EV, Bovbjerg DH, Jandorf L, Ciupak G, Davis W, Pawlish KS, Liang P, Singh KK. CAG Repeat variants in the POLG1 gene encoding mtDNA polymerase-gamma and risk of breast cancer in African-American women. PLoS One. 7(1):e29548., 2012 66. Hall BM, Owens K, Singh KK, Distinct Functions of Evolutionary Conserved MSF1

and LEA-like Domains in Mitochondria, Journal of Biological Chemistry, 286:39141–39152, 201.


23

65. Ayyasamy V, Owens KM, Desouki MM, Liang P, Bakin A, Thangaraj K, Buchsbaum DJ, LoBuglio AF, Singh KK, Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin. PloS ONE, 6(9): e24792. doi:10.1371/journal.pone.0024792, 2011

64. Owens KM, Kulawiec M, Desouki MM, Ayyasamy V, and Singh KK, Impaired OXPHOS

complex III in breast cancer. PloS ONE, 6(8): e23846.doi:10.1371/ journal.pone.0023846, 2011

63. Desler C, Lise MM, Singh KK, Rasmussen LJ, The importance of mitochondrial DNA

in aging and cancer, Journal of Aging research. 2011:407536, 2011. 62. Gonçalves AP, Máximo V, Singh KK, Soares P, and Videira A Involvement of p53 in

cell death following cell cycle arrest and mitotic catastrophe induced by rotenone. Biochim Biophys Acta. 1813(3):492-499, 2011.

61. Erikstein BS, Hagland HR, Nikolaisen J, Kulawiec M, Singh KK, Gjertsen BJ Tronstad

KJ, Cellular Stress induced by resazurin leads to autophagy and cell death due to impairment of mitochondrial function. Journal of Cellular Biochemistry, 111:574-584, 2010.

60. Saneto, R and Singh KK, Illness induced exacerbation of Leigh syndrome in a patient

with the MTATP6 mutation, T9185C, Mitochondrion, 10:567-572, 2010. 59 Graham K, Kulawiec M, Owens K, Li X, Desouki MM, Chandra D and Singh KK,

NADPH oxidase 4 is an oncoprotein localized to the mitochondria, Cancer Biology and Therapy 10:223-231, 2010.

This article was highlighted on the cover of the journal. 58. Rangel R, McKeller MR, Sims-Mourtada JC, Cain K, Kashi C, Melnikova V,

Ananthaswamy HN, Blackburn MR, Cande C, Larochette N, Kroemer G, Singh K.K., and Martinez-Valdez, H. PRELI protects mitochondria, prevents AIF nuclear translocation and opposes apoptosis. Cell Death and Disease: e21; doi:10.1038/cddis.2009.19, 2009

57. Kim H, Patel K, Muldoon-Jacobs K, Bisht KS, Aykin-Burns N, Pennington JP, Riet van

der Meer R, Nguyen P, Savage J, Owens K M. Vassilopoulos A, Ozden O, Park S, Singh

KK, Abdulkadir SA, Spitz DR. Deng , C and Gius D, SIRT3 is a Mitochondrial Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism, Cancer Cell, 17:41-52, 2010.

56. Yang D, WangM-Z, Tang Y, Chen Y, Jones T, Brewer G, Rao K, Singh K.K. and Nie D, Impairment of Mitochondrial Respiration in Mouse Fibroblasts by Oncogenic H-Ras, Cancer Biology and Therapy, 9:122-133, 2010.


24

55. Kulawiec M, Owens K, Singh K.K. mtDNA G10398 variant in African-American women with breast cancer provide resistance to apoptosis and promote metastasis in mice. Journal of Human Genetics, 54:647-54, 2009.

54. Singh KK, Ayyasamy V, Owens K, Kaul MS and Vujcic M., Mutations in mitochondrial DNA polymerase γ promote tumorigenesis, Journal of Human Genetics 54:516-524, 2009.

53. Kulawiec M, Owens K, Singh KK., Cancer cell mitochondria confer apoptosis resistance and promote metastasis, Cancer Biology and Therapy, 8: 69 – 76, 2009.

This article was highlighted on the cover and showcased with a commentary titled “Mutant Mitochondria and Cancer Cell Metastasis: Quest for a Mechanism (8:14, 2009) describing the novelty of our research in identifying a role for mutant mtDNA in metastasis.

52. Kulawiec M, Ayyasamy V, Singh KK., P53 regulates mtDNA copy number and mitocheckoint pathway, Journal of Carcinogenesis, 8 (1) 8-16, 2009.

51. Hall BM, Ma C-X Liang P and Singh KK, Fluctuation AnaLysis CalculatOR (FALCOR): a

web tool for the determination of mutation rate using Luria-Delbrück fluctuation analysis. Bioinformatics, 25:1564-1565, 2009.

50. Kulawiec M, Safina A, Desouki MM, Still I, Matsui Sei-Ichi, Bakin A, Singh KK Tumorigenic Transformation of Breast Epithelial Cells induced by depletion of

mitochondrial DNA. Cancer Biology and Therapy, 7(11) 1732 – 1743, 2008. This article was highlighted on the cover of the journal describing the significance of

our research showing the role of mtDNA in tumorigenic transformation. 49. Smirgalia D.J. , Kulawiec M, Bistulfi G, Ghoshal S, Singh K.K. A novel role for

mitochondria in regulating epigenetic modification in the nucleus, Cancer Biology and Therapy, 7(8) 1182 – 1190, 2008

This article was highlighted on the cover and showcased with a commentary titled “Mitochondrial Control of Epigenetics” (7:1191-1192, 2008) describing the novelty of our research in merging the fields of mitochondrial biology with epigenetics.

48. De Chaudhuri Sujata, Kundu M, Banerjee M, Das JK, Majumdar P, Basu S, Roychoudhury S, Singh K.K. and Giri A.K., Arsenic induced health effects and genetic damage in keratotic individuals: involvement of p53 arginine variant and chromosome aberrations in arsenic susceptibility, Mutation Research. 625:112-24, 2007

47. Katrangi E, D’Souza G, Boddapati SV, Kulawiec, M, Singh K.K., Biggger B, Weissig V.,

Xenogenic transfer of isolated murine mitochondria into human o cells can improve respiratory function, Rejuvenation Research, 10:561-70, 2007


25

46. Vujcic M, Shroff M, and Singh K. K, Genetic determinants of mitochondrial response to arsenic in yeast Saccharomyces cerevisiae, Cancer Research 67:9740-9749, 2007

45. Weinberger M, Feng L, Paul A, Smith DL, Hontz RD, Smith JS, Vujcic M, Singh K.K,

Huberman JA, and Burhans WC, DNA replication stress is determinant of chronological life span in budding yeast. PloS ONE, 2:e748, 2007.

44. Desler, C., Munch-Petersen, B., Stevnsner, T., Matsui, S-I., Kulawiec, M., Singh, K.K.

and Rasmussen, L.J. Mitochondria as determinant of nucleotide pool and chromosomal stability. Mutation Research, 625(1-2):112-24, 2007.

43. Kulawiec, M., Arnouk, H., Desouki, M., Kazim, L., Still, I., and Singh, K.K. Proteomic

analysis of proteins involved in mitochondria-to-nucleus retrograde response in human cancer cells. Cancer Biology and Therapy, 8:967-975 , 2006. This article was showcased with a commentary describing the novelty of our research in identifying oncogene and tumor suppressors regulated by mitochondria (Cancer Biology and Therapy 5:967-977, 2006)

42. Singh, K.K., Desouki, M.M., Franklin, R.B., Feng, P., Costello, L.C. Mitochondrial

aconitase in malignant and nonmalignant prostate. Molecular Cancer 5: 14-21, 2006. 41. Zhang, H., Chatterjee, A. and Singh, K.K. Saccharomyces cerevisiae polymerase ζ

functions in mitochondria. Genetics 172: 2683-2688, 2006. 40. Gourley, P.L., Hendricks, J.K., McDonald, A.E., Copeland, R.G., Barrett, K.E., Gourley,

C.R., Singh, K.K., Naviaux, R.K. Mitochondrial Correlation Microscopy and Nanolaser Spectroscopy - New Tool for Biophotonic Detection of Cancer in Single Cells. Technology in Cancer Research and Treatment 4: 585-592, 2005.

39. Desouki, M.M., Kulawiec, M., Bansal, S., Das, G.M., Singh, K.K. Cross Talk Between

Mitochondria and Superoxide Generating NADPH Oxidase in Breast and Ovarian Tumors. Cancer Biol Ther 4(12) 1367-1373, 2005.

38. Franklin, R.B., Feng, P., Milon, B., Desouki, M.M., Singh, K.K., Kajdacsy-Balla, A.,

Bagasra, O., Costello, L.C. hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer. Molecular Cancer 4: 32, 2005.

37. Singh, K.K., Kulaweic, M., Still, I., Desouki, M.M., Geradts, J., Matsui, S-I. Inter-

genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. Gene 354: 140-6, 2005.

36. Ambrosone, C.B., Ahn, J., Singh, K.K., Rezashiraz, H., Furberg, H., Sweeney, C., and

Trovato, A. Variability in genes related to oxidative stress and survival after treatment for breast cancer. Cancer Research 65: 1105-1111, 2005.


26

35. Park, S.Y., Bongkun, C., Park, Y.M., Singh, K.K., Lee, M-S. Cellular aging of mitochondrial DNA-depleted cells. Biochemical Biophysical Research Communications 325: 1399-1405, 2004.

34. Kachhap, S. and Singh, K.K. Expression of uracil glycosylase inhibitor in

mitochondria is not mutagenic. Molecular Cancer 3: 32-36, 2004. 33. Mori, N., Delsite, R., Natarajan, K., Bhujwalla, Z.M. and Singh. K.K. Loss of p53

function in colon cancer cells results in increased phosphocholine and total choline. Molecular Imaging 3: 319-323, 2004.

32. Modica-Napolitano, J. and Singh, K.K. Mitochondrial dysfunction in cancer.

Mitochondrion 4: 755-762, 2004. 31. Singh, K.K. Mitochondria damage checkpoint in apoptosis and genome stability.

FEMS Yeast Research 5: 127-132, 2004. 30. Park, S.Y., Chang, I., Kang, S.W., Park, S-H., Singh, K.K. and Lee, M-S, Resistance of

mitochondrial DNA-depleted cells against cell death: Role of mitochondrial superoxide dismutase. J Biol Chem 279: 7512-7520, 2004.

29. Singh, K.K., Mitochondrial dysfunction is a common phenotype in aging and cancer.

Ann of NY Acad of Sci 1019: 260-264, 2004. 28. Singh, K.K., Rasmussen, A.K., Rasmussen, L.J. Genome wide analysis of signal

transducers and regulators of mitochondrial dysfunction in Saccharomyces cerevisiae. Ann NY Acad Sci 1011: 284-298, 2004.

27. Delsite, R.L., Rasmussen, L.J., Rasmussen, A.K., Kalen, A., Goswami, P.C. and Singh,

K.K. Mitochondrial impairment is accompanied by impaired DNA repair in the nucleus. Mutagenesis, 18: 497-503, 2003.

26. Rasmussen, A.K., Chatterjee, A., Rasmussen, L.R. and Singh, K.K. Mitochondria-

mediated-mutator phenotype in Saccharomyces cerevisiae. Nucleic Acid Research 31: 3909-3917, 2003.

25. Zhou, S., Kachhap, S. and Singh, K.K. Mitochondrial impairment in p53 deficient

human cancer cells. Mutagenesis 18: 287-292, 2003. 24. Delsite, R.D., Kachhap, S., Anbazhagan, R., Gabrielson, E., and Singh, K.K. Nuclear

genes involved in mitochondria-to-nucleus communication in breast cancer cells. Molecular Cancer 1: 6-15, 2002.

23 Kim, G., Sikder H. and Singh, K.K. A colorimetric method identifies the vulnerability

of mitochondria to oxidative damage. Mutagenesis 17: 375-381, 2002 .


27

22. Naviaux, R. and Singh, K.K. Manipulations of the mitochondrial germ line must be openly debated and followed up. Nature 413: 347, 2001.

21. Chatterjee, A. and Singh, K.K. Uracil-DNA glycosylase deficient yeast exhibits a

mitochondrial mutator phenotype. Nucleic Acid Research 29: 4935-4940, 2001 . 20. Thorburn D.R., Hans-Henrik, D.M,, and Singh, K.K. Pros and cons of mitochondrial

manipulation in the human germ line. Mitochondrion 1: 123-127, 2001 19. Jäger, A.C., Rasmussen, M., Bisgaard, H.C., Singh, K.K., Nielsen, F.C., and Rasmussen,

L.J. HNPCC Mutations in the Human DNA Mismatch Repair Gene hMLH1 Influence Assembly of hMutL and hMLH1-hEXO1 Complexes. Oncogene 20: 3590-3595, 2001.

18. Singh, K.K., Sigala, B., Sikder, H.A., Kim, G., and Schwimmer, C. Inactivation of

Saccharomyces cerevisiae OGG1 gene leads to increase frequency of mitochondrial deletions. Nucleic Acid Research 29: 1381-1388, 2001.

17. Parker, A., Gu, Y., Mahoney, W., Suk-Hee, L., Singh, K.K., and Lu, A. Human homolog

of the MutY repair protein (hMYH) physically interacts with proteins involved in long-patch DNA base excision repair. J Biol Chem 276: 5547-5555, 2001.

16. Singh, K.K. Mitochondrial me and the Mitochondrion journal. Mitochondrion 1: 1-2,

2000. 15. Singh, K.K. The Saccharomyces cerevisiae Sln1p-Ssk1p two-component system

mediates response to oxidative stress and in an oxidant specific fashion. Free Rad Biol Med 29: 1043-1050, 2000.

14. Rasmussen, L.J., Rasmussen, M., Bisgaard, H.C., Singh, K.K. The human cyclin B1

modulates the sensitivity of DNA mismatch repair deficient cancer cells to alkylating agents. Exp Cell Res 257: 127-134, 2000.

13. Singh, K.K., Russell, J., Sigala, B., Zhang, Y., Williams, J.R., Keshav, K.F. Mitochondrial

DNA determines the cellular response to cancer therapeutic agents. Oncogene 18: 6641-6646, 1999.

12. Negelhus T, Huag, T., Singh, K.K., Keshav, K.F., Skorpen, F., Oteerlei, M., Bharati, S.,

Lindmo, T., Benichou, S., Benarous, R., and Krokan, H.E. Human Uracil-DNA gylcosylase interacts with the C-terminal part of the 34 KDa subunit of replication protein A. J Biol Chem. 272: 6561-6566, 1997.

11. Singh, K.K. and Hinemann, J. Yeast plasmids pp. 113-130. Methods in Molecular

Biology: Expression and Detection of Recombinant genes. Vol. 62, R. Tuan Ed, Humana Press Inc., Totowa, NJ, 1996.


28

10. Singh, K.K. and Samson, L. Replication protein A binds to regulatory elements in yeast DNA repair and DNA metabolism genes. Proc Natl Acad Sci 92: 4907-4911, 1995.

9. Xiao, W., Singh, K.K.*, Chen, B., and Samson, L. A common element involved in

transcriptional regulation of two DNA alkylation repair genes (MAG1 and MGT1) of Saccharomyces cerevisiae. Mol Cell Biol 13: 7213-7221, 1993.

8. Singh, K.K., Small, G.M., and Lewin, A.S. Alternative topogenic signals in

peroxisomal citrate synthase of Saccharomyces cerevisiae. Mol Cell Biol 12: 5593-5599, 1992.

7. Garret, J.M., Singh, K.K., Vonder Haar, R.A, and Emr, S.D. Mitochondrial protein

import: isolation and characterization of Saccharomyces cerevisiae MFT1 gene. Mol Gen Genetics 225: 483-491, 1991.

6. Singh, K.K. and Norton, R.S. Metabolic changes induced during adaptation of

Saccharomyces cerevisiae to a water stress. Arch Microbiol 156: 38-42, 1991. 5. Mackenzie, K.F., Singh, K.K., and Brown, A.D. Water stress plating hypersensitivity

of yeasts: Protective role of trehalose in Saccharomyces cerevisiae. J Gen Microbiol 134: 1661-1666, 1988.

4. Singh, K.K. and Vincents, W.S. Clumping characteristic and hydrophobic behavior of

an isolated bacterial strain from sewage sludge. Appl Microbiol Biotech 25: 396-398, 1987.

3. Brown, A.D., Mackenzie, K.F., and Singh, K.K. Selected aspects of microbial

osmoregulation. FEMS Micro Rev 39: 31-36, 1986. 2. Saxena, V.K., Tandon, S.M., and Singh, K.K. Anaerobic fermentation of cattle dung

supplemented with water-hyacinth and green algae. Natl Acad Sci Lett 7: 130-133, 1984.

1. Singh, K.K. and Verma, J. Methanogenesis with cheese industry waste water. Natl

Acad Sci Lett 6: 275-277, 1983. BOOKS PUBLISHED 3. Singh K.K. and Costello C (editors) Mitochondria and Cancer, Springer, NY, 2008. 2. Singh, K.K. (Editor) Oxidative Stress, Disease and Cancer. Imperial College Press,

London, United Kingdom, 2006 1: Singh, K.K. (Editor) Mitochondrial DNA mutations in Aging, Disease, and Cancer.

Springer, New York, NY, 1998


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BOOK CHAPTERS AND REVIEWS 17. Guo S, Singh KK, Lillard JW. Leptin Signaling in Stem Cell and Cancer Stem Cells.

Cancer Stem Cells. The Prestigious Wiley Press, accepted, 2013 16. Chandra D and Singh KK. Genetic insights into OXPHOS defects and its role in

cancer (Biochim Biophys Acta. 1807:620-5, 2011. 15: Owens K, Modica-Napolitano JS and Singh, Mitochondria and Cancer, In Singh K.K.

and Costello C (editors) Mitochondria and Human Cancer, Springer, NY, 2008. 14. Ghosh P, Basu A, Singh K.K., and Giri AK. Evaluation of cell types for assessment of

cytogenetic damage in arsenic exposed population, Molecular Cancer, 7:45, 2008. 13. Singh K.K. and Kulawiec M, Mitochondrial DNA polymorphism and risk of cancer.

Methods Mol Biol. 2009; 471:291-303. 12. Verma M, Naviaux RK, Tanaka M, Kumar D, Franceschi C, Singh KK. Mitochondrial

DNA and cancer epidemiology. Cancer Res. 15;67(2):437-9, 2007. 11. Modica-Napolitano JS, Kulawiec M, Singh K.K. Mitochondria and human cancer.

Curr Mol Med. 7(1):121-31, 2007 10. Singh, K.K., Shroff, M. and Vujcic M. Genetic mechanisms of arsenic induced

carcinogenesis. In: Natural Arsenic in Ground Waters-health impact, remediation and management. Editors: J. Bundschuh, P. Bhattacharya, MA Armienta, J. Matschullat, ME Garcia. Taylor and Francis Group, NY, pp 427-435, 2007.

9. Goswami, P. and Singh, K.K. Oxidative Stress and Multistage Carcinogenesis. In

Oxidative stress, disease and cancer. Editor: K.K. Singh. Imperial College Press, London, United Kingdom, 2006.

8. Singh, K.K. Mitochondria Damage Checkpoint, Aging and Cancer. Ann NY Acad Sci

1067: 184-192, 2006. 7. Rassmussen, L.J. and Singh, K.K. Oxidative Damage and Repair in the Mitochondrial

Genome. In: Oxidative damage to Nucleic Acid. Editors: M. Evans & M. Cooke). Landes Biosciences, Georgetwon, Texas, USA, 2006.

6. Singh, K.K. Nanotechnology in Cancer Detection and Treatment. Technology in

Cancer Research and Treatment. 4: 583-584, 2005. 5. Singh, K.K., Luccy, B.M., and Zullo, S.J. Mitochondria, Oxidative Stress and

Mitochondrial Diseases. In: Oxidative Stress and Aging: Advances in Basic Science, Diagnostics, and Intervention. World Scientific Publishing Company, New York, NY, pp. 452-466, 2003.


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4. Modica-Napolitano, J. and Singh, K.K. Mitochondria as targets for detection and

treatment of cancer. Expert Reviews in Molecular Medicine. 2002:1-19., 2002. 3. Rassmussen L and Singh, K.K. Genetic integrity of mitochondrial genome. In:

Mitochondrial DNA mutations in Aging, Disease, and Cancer. Springer, New York, NY, 1998.

2. Kang, D., Takeshig, K., Sekiguchi, M., and Singh, K.K. Mitochondrial DNA mutations

in Aging, Disease, and Cancer: An Introduction. In: Mitochondrial DNA Mutations in Aging, Disease, and Cancer, Springer, New York, NY, 1998.

1. Singh, K.K. (Editor) Mitochondrial DNA mutations in Aging, Disease, and Cancer.

Springer, New York, NY, 1998. PATENTS Singh, K.K. (2003) Colorimetric test for agents that induce mitochondrial dysfunction. US Patent number 6,479,251. EXTRAMURAL FUNDING CURRENT GRANTS NIH/R01 Mitochondria in Prostate Cancer Diversity Direct Costs: $230,000 per year Role: Principal Investigator: Keshav K. Singh Dates: 4/01/2016 – 03/31/2021 Mike Silve Foundation Grant Award Novel functions of mitochondria localized androgen receptor in prostate cancer Role: Principal Investigator: Keshav K. Singh Direct Costs: $50,000 Dates: 02/01/2018 – 12/31/2019 Indo US Science and Technology Forum Indo-US Conference on Human Diversity and Health Disparities Role: US Organizer Direct Costs: $12,000 Dates: 01/16/2020 -01/18/2020. PENDING GRANTS DOD Racial Disparities in Prostate Cancer: Role of Mitochondrial Ancestry Role: Principal Investigator: Keshav K. Singh NIH/R01


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miRNA regulators of inter-organelle communication in Cancer Role: Principal Investigator: Keshav K. Singh NIH/R01 Metal, Mitochondria and Malignancy Role: Principal Investigator: Keshav K. Singh NIH/ R01 Nuclear Transfer of mtDNA in Cancer Role: Principal Investigator: Keshav K. Singh NIH/R01 Mitochondrial Dysfunction in Triple Negative Breast Cancer Role: Principal Investigator: Keshav K. Singh PREVIOUS FUNDING VA Merit Review Award 1I01BX001716-01A2 Role: Principal Investigator: Keshav K. Singh Mechanisms of arsenic-induced carcinogenesis Direct Costs: $266,481 per year Dates: 10/01/2013 – 12/31/2018 LAPS Pilot Project Pilot Project: Numtogenesis during tumorigenesis Role: Principal Investigator: Keshav K. Singh Direct Costs: $20,000 Dates: 10/1/2015 – 09/30/2017 NIH U54 Cancer Research in Health Diversity Pilot Project: Targeting Mitochondrial Dynamics for TNBC therapy Role: Principal Investigator: Keshav K. Singh Direct Costs: $40,000 per year Dates: 08/1/2015 – 08/31/2016 NIH/R21 ES023091 Role: Principal Investigator: Keshav K. Singh Arsenic Repression of GADD153 and Breast Cancer Direct Costs: $150,000 per year Dates: 08/20/2013 – 08/31/2016 NIH/R21 1R21CA176054-01 Role: Principal Investigator: Keshav K. Singh Mitochondrial DNA and prostate cancer in African American Direct Costs: $130,500 per year Dates: 08/1/2013 – 08/31/2016


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Role: Principal Investigator: Keshav K. Singh Tumorigenic role of mitochondria in African-American women Direct Costs: $124,500 per year Dates: 09/01/10-8/31/14 NIH/R21 NIH/R21 CA153097-01 Role: Multiple Principal Investigator: Keshav K. Singh Therapeutic implication of estrogen receptor-p53 interaction in mitochondria Direct Costs: $120,000 per year Dates: 03/01/12-2/28/14 NIH/RO1 CA 121904 Principal Investigator: Keshav K. Singh Direct Costs: $179, 673 per year Mitochondria and Carcinogenesis Dates: 07/01/06-11/30/14 NIH/RO1 CA116430 Principal Investigator: Keshav K. Singh Loss of FLJ13639 Expression in Acute Leukemia Direct Costs: $172, 353 per year Dates: 07/01/06-11/30/12 NIH/1R01 CA113655 Role: Principal Investigator: Keshav K. Singh Mitochondria and Mutagenesis Direct Costs: $177, 500 per year Dates: 04/1/06-3/31/13 NIH-UAB-Breast Cancer Spore Pilot Project Principal Investigator Keshav K. Singh Mitochondrial Genetic Strategy to Identify Key Molecules as Potential Therapeutic Targets Direct Costs: $50,000 per year Dates: 5/01/11-8/31/13 Department of Defense Post Doctoral Fellowship to Kjerstin Owens, Ph.D. Role of Polymerase Gamma Mutations in Breast Tumorigenesis Mentor: Keshav K. Singh Direct Costs: $110, 449 per year Dates: 08/01/09--1/31/11 US CDC-India Collaborative Grant Principal Investigator USA: Keshav K. Singh


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CGH array analysis of individuals with and without arsenic induced skin lesions Direct Costs: $25,000 per year Dates: 09/01/10-11/30/11 Department of Science and Technology, India Collaborative Project: Scientist and Technologist of Indian Origin (STIO) Principal Investigator (USA): Keshav K. Singh Host Investigator (India): K. Thangaraj, Center for Cellular and Molecular Biology, Hyderabad, India Development of Diagnostic Technologies for Emerging Mitochondrial Diseases Direct Costs: $10,000 per year Seahorse Biosciences, Principal Investigator: Keshav K. Singh Society for Mitochondria Research and Medicine, India MitoIndia Meeting 2010 Direct Costs: $ 2, 500 Dates: 11/12/2010-11/14/2010 Edison Pharma Indo-US meeting on Mitochondrial Research and Medicine Principal Investigator: Keshav K. Singh Direct Costs: $ 2,500 Dates: 011/12/08-11/14/08 New York State Health Research Science Board Role: Mentor Breast Cancer Research and Education Program PostDoctoral Fellowship for Mariola Kulawiec, Ph.D. Mitochondrial DNA instability in breast tumorigenesis Direct Costs: $120,000 Dates: 04/1/06-3/31/08 Roswell Park Alliance Foundation Supplemental Fund to NIH RO1-121904 Mitochondria and Carcinogenesis Principal Investigator: Keshav K. Singh Direct Costs: $ 30,000 Dates: 11/1/06-4/30/08 Roswell Park Alliance Foundation Supplemental Fund to NIH RO1-113655 Mitochondria and Mutagenesis Principal Investigator: Keshav K. Singh Direct Costs: $ 35,000 Dates: 08/1/06-7/31/07


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Indo-US Science and Technology Forum Role: USA Principal Investigator, Keshav K. Singh Indo-US Workshop on Mitochondrial Research and Medicine Direct Costs: $39,419 Dates: 1/22/07-1/25/07 Edison Pharma Role: Principal Investigator, Keshav K. Singh Indo-US workshop on Mitochondrial Research and Medicine Direct Costs: $5,000 Dates: 1/22/07-1/25/07 March of Dimes Role: Principal Investigator, Keshav K. Singh Indo-US workshop on Mitochondrial Research and Medicine Direct Costs: $5,000 Dates: 1/22/07-1/25/07 Charlotte Geyer Foundation Mitochondria and Mutagenesis Principal Investigator: Keshav K. Singh Dates: 07/01/05-3/31/06 Direct Costs: $65,000 Breast Cancer Coalition of Rochester MitoChip Expression Array: A Genomic Approach to Identify New Breast Cancer Genes Principal Investigator: Keshav K. Singh Dates: 01/01/05-4/1/06 Direct Costs: $40,000 National Institute of Health/R01 MtDNA Mutagenesis by Environmental Carcinogens Principal Investigator: Keshav K. Singh Dates: 2/1/99 – 1/31/06 Direct Costs: $350,000 Elsa V. Pardee Foundation Mitochondria-to-Nucleus Communication in Breast Cancer Principal Investigator: Keshav K. Singh Dates: 10/01/02-9/30/05 Direct Costs: $204,881 Muscular Dystrophy Association Conference Grant Special meeting grant for Mitochondria 2003 Principal Investigator: Keshav K. Singh Dates: 6/11/03 – 6/14/03


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Direct Costs: $8,000 R24 CA92871 Principal Investigator: Martin Pomper Co-Investigator: Keshav K Singh Effort: 3% Salary Support Interdisciplinary Small Animal Imaging for Oncology Dates: 07/01/01-06/30/03 National Institute of Health /P-20, Multidisciplinary Functional Imaging of Cancer Principal Investigator Project 3: Keshav K. Singh Metabolic Imaging of Cancer Cells Deficient in Mitochondrial Function Dates: 5/1/00-4/30/03 National Institute of Health/P50 Breast Cancer SPORE Principal Investigator: Nancy Davidson Principal Investigator Pilot Project 4: Keshav K. Singh Mitochondrial Dysfunction and Breast Cancer Dates: 4/30/01 – 3/30/02 Direct Costs:$40,000 American Heart Association Molecular Analysis of Mitochondrial Dysfunction Induced by Anthracycline Therapy Principal Investigator: Keshav K. Singh Dates: 1/1/99 – 12/31/02 Direct Costs: $259,900 Special symposium grant: yeast as model for human mitochondrial disorders Muscular Dystrophy Association Conference Grant Principal Investigator: Keshav K. Singh Dates: 6/28/01 – 3/4/01 Direct Costs: $5,000 Special symposium grant: yeast as model for human mitochondrial disorders Serono Foundation for Advancement of Medical Science Principal Investigator: Keshav K. Singh Dates: 8/25/01 – 8/26/01 Direct Costs: $5,000 March of Dime Special symposium grant for yeast as model for human mitochondrial disorders Principal Investigator: Keshav K. Singh Dates: 8/25/01 – 8/26/01 Direct Costs: $1,000


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Muscular Dystrophy Association Conference Grant Special meeting grant for Mitochondria 2001 Principal Investigator: Keshav K. Singh Dates: 2/28/01 – 3/4/01 Direct Costs: $16,000 Alexander & Margaret Stewart Trust Molecular Mechanisms Underlying Chromosomal Instability in Colorectal Cancer Cells Principal Investigator: Keshav K. Singh Dates: 9/1/97 – 12/31/99 Direct Costs: $25,000 CRG 961204 NATO Collaborative Research Grant DNA Mismatch Repair in Mitochondria Principal Investigator: Keshav K. Singh Dates: 2/1/97 – 1/31/99 Direct Costs: $3,500 Johns Hopkins Cancer Center Pilot Projects Molecular Mechanisms of Radiation-induced Breast Cancer Role: Principal Investigator: Keshav K. Singh Dates: 7/1/97 – 6/30/98 Direct Costs: $25,000

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