Curriculum Vitae and Bibliography Nelson Leung, MD

Address: 200 First Street SW Rochester, MN 55905

leung.nelson@mayo.edu

1. PERSONAL INFORMATION

Citizenship:

United States

2. PRESENT ACADEMIC RANK AND POSITION

Professor of Medicine- College of Medicine, Mayo Clinic Associate Professor of Medicine - College of Medicine, Mayo Clinic Assistant Professor of Medicine- College of Medicine, Mayo Clinic Lecturer - College of Medicine, Mayo Clinic Consultant - Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota Consultant - Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota

2014 2010 – 2014 2003 – 2010 1997 – 2003 2003 - Present 09/08/2010 - Present

3. EDUCATION

Santa Clara University BS, Combined Sciences

1985 - 1989

Creighton University Medical School MD

1990 - 1994

University of Iowa Internship, Internal Medicine

1994 - 1995

Mayo Graduate School of Medicine, College of Medicine, Mayo Clinic Residency, Internal Medicine

1995 - 1997

Mayo Graduate School of Medicine, College of Medicine, Mayo Clinic Fellowship, Nephrology

1997 - 2000

4. BOARD CERTIFICATION(S)

American Board of Internal Medicine

Diplomate in Internal Medicine

1997

Diplomate in Internal Medicine Diplomate in Nephrology

2000/2010 2000/2020

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5. LICENSURE

Minnesota

38234

6. HONORS/AWARDS

Laurent Award – Division of Nephrology and Hypertension 2012

7. MILITARY SERVICE

8. PREVIOUS PROFESSIONAL POSITIONS AND MAJOR APPOINTMENTS

Emergency Medical Technician - San Jose City College, San Jose, California

1985

Lab Technician II - Genelabs, Redwood City, California

1989 - 1990

Emergency Room Physician - Austin Medical Center, Mayo Health System, Austin, Minnesota

1995 - 1999

Emergency Room Physician - Falls Memorial Hospital, International Falls, International Falls, Minnesota

1999 - 2003

Senior Associate Consultant - Division of Nephrology & Internal Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota

2000 - 2003

9. PROFESSIONAL & COMMUNITY MEMBERSHIPS, SOCIETIES AND SERVICES

Professional Memberships & Services

American Society of Nephrology Member

2000 - present

American Society of Hematology Member

2005 - present

International Society of Amyloidosis Member

2009 - present

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The International Myeloma Society Member

2010 – present

International Myeloma Working Group Member

International Kidney Monoclonal Gammopathy Research Group Founding member and current President Rochester Science Fair Rochester, MN Judge Hong Kong Society Of Nephrology Grant Reviewer Consensus Panel for revising the "Definition of Organ Involvement and Treatment Response in Immunoglobulin Light Chain Amyloidosis (AL): A Consensus Opinion From the 10th International Symposium on Amyloid and Amyloidosis" Member

2013 – present 2011 – present 1999 – 2002 2008, 2011, 2012 2009 - 2010

The German National Funding Initiative for Rare Disease Grant Reviewer XII International Symposium on Amyloidosis, St. Peter’s Rome. Abstract reviewer Hong Kong Renal Commissioned Training 2012 Living Donor Renal Transplantation: From Legislation, Protocol, Procedure to Outcome Co-Chair Leukaemia & Lymphoma Research Grant Reviewer International Myeloma Workshop Kyoto, Japan Myeloma-related renal impairment session Moderator American Society of Nephrology Annual Meeting Abstract Reviewer

2005, 2011 2010 2012 2013 4/06/13 2013

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The Royal Society of Medicine Myeloma Amyloid meeting London, UK Chair of panel discussion on diagnostic and prognostic advances Collaborative Management of Multi-System Diseases: New Developments and Treatment Strategies Galway, Ireland Co-organizer IKMG satellite meeting of the XIV International Symposium on Amyloidosis Indianapolis Organizer

2013 2014 2014

Hong Kong Society of Myeloma Scientific Meeting Hong Kong Organizer First International Congress of Chinese Nephrologists Hong Kong Co-Chair - Hypertensive nephropathy – clinical research

2014 2015

Journal Other Responsibilities

American Journal of Hematology – Reviewer American Journal of Kidney Diseases – Reviewer American Journal of Nephrology – Reviewer Amyloidosis - Reviewer Archives of Internal Medicine - Reviewer Blood - Reviewer Haematologica - Reviewer Kidney International - Reviewer Nephrology Dialysis Transplantation - Reviewer Section Editor – Clinical Nephrology

2016 -

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10. EDUCATIONAL ACTIVITIES

A. Curriculum/Course Development Disease Specific Management I Nephrology Trainee Noon Conference Lecturer Mayo Clinic Rochester, Minnesota

2000 - Present

Nephrology Continuity Clinic. Supervising Consultant for Mayo Clinic Rochester, Minnesota

2002 - 2010

Annual Update in Nephrology and Kidney/Pancreas Transplantation course Member of the Planning Committee Mayo Clinic Rochester, Minnesota

2003 - 2004

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B. Teaching Treatment of Primary Systemic Amyloidosis with High Dose Chemotherapy and Peripheral Blood Stem Cell Transplantation The Renal Response and Nephrotoxicity The Trojan Horse of Solid Organ Transplantation. Transplantation Grand Rounds. Mayo Clinic. Rochester, Minnesota Nephrologic Approach to An Itchy Subject. Hepatology Grand Rounds. Mayo Clinic Rochester, Minnesota Dysproteinemias: The Union of Hematology and Nephrology American Nephrology Nurses’ Association Rochester, Minnesota Hepatorenal Syndrome: The Tide is Turning. Critical Care Grand Rounds. Mayo Clinic Rochester, Minnesota Light Chain Associated (AL) Amyloidosis Past, Present and Future Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Renal Failure in Multiple Myeloma: Is Plasmapheresis the Right Therapy? Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Nephrogenic Systemic Fibrosis What Nephrologists Need to Know Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota AA: The Other Amyloidosis Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Management of Myeloma Cast Nephropathy Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Prevention of AKI in ICU patients: What should we be doing? Critical Care Grand Rounds. Mayo Clinic Rochester, Minnesota

12/04/2001 07/30/2002 07/25/2003 03/19/2004 08/04/2005 08/30/2005 09/12/2006 07/31/2007 04/08/2008 03/26/2009 07/23/2009

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Toxic Light Chain and the Kidney Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Treatment of Multiple Myeloma Patients with Acute Renal Failure Hematology Thursday Morning Conference Mayo Clinic Rochester, Minnesota Renal Issues in Heme/Onc/BMT Hematology/Oncology/BMT Nursing Forum Mayo Clinic, Rochester, Minnesota

02/08/2011 03/17/2011 03/28/2011

Lupus Nephritis Mayo Clinic, Division of Rheumatology Rochester Minnesota Monoclonal Gammopathy of Renal Significance Nephrology Grand Rounds Mayo Clinic Rochester, Minnesota Hepatorenal Syndrome Nephrology Fellows Core Lecture

12/01/2011 02/19/2013 1/2/2014

C. Mentorship Individual and Position

Timeframe & Description

Institution

Current Status

Caudaro, Silvania Fellow

2003-2004 Clinical research

Cohen, Ari Fellow

2001- 2002 Collaborated on a manuscript

Villicana, Rafael Internal Medicine Resident

2002 - 2003 Clinical research

Cedars-Sinai Medical Center

Associate Director of Kidney Transplantation

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Buehrig, Christopher Nephrology Fellow

2003 - 2004 Multiple Clinical research projects

Private practice

Gyamlani, Geta Nephrology Fellow

2003 - 2004 Clinical research

University of Mississippi

Assistant professor

Soares Herrmann, Sandra Internal Medicine Resident

2004 - Present Multiple research projects, clinical study.

Mayo Rochester

Associated consultant

Swaminathan, Sundararaman Nephrology Fellow

2004 - 2006 Multiple Clinical research projects

University of Virginia

Associate professor

Nyholm, Brett Nephrology Fellow

2005 - 2007 Clinical research

Private practice

Bittar, Camila Visiting Clinician

2006 Clinical research

Amer, Hatem Nephrology Fellow

2006 - 2008 Clinical research

Mayo Rochester

Assistant Professor

Shaikh, Aisha Nephrology Fellow

2006 – 2008 Clinical research

Private practice

Lorenz, Elizabeth C Nephrology Fellow

2007 - Present Multiple research projects

Mayo Rochester

Assistant Professor

Naina, Harris Hematology Fellow

2007 - 2010 Clinical research

University of Texas Southwestern Medical Center

Assistant Professor,

El-Zoghby, Ziad M Nephrology Fellow

2007 - 2009 Clinical research

Mayo Rochester

Assistant Professor

Eirin Massat, Alfonso Visiting Clinician

2008 - Present Clinical research

Mayo Rochester

Senior Research Fellow

Irazabal, Maria Visiting Clinician

2008 - Present Clinical research

Mayo Rochester

Research associate

Craici, Iasmina M Nephrology Fellow

2009 - 2010 Clinical research

University of Mississippi Medical Center

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Wagner, Steven J Nephrology Fellow

2009 - 2010 Clinical research

University of Mississippi Medical Center

Schinstock, Carrie Nephrology Fellow Tsapenko, Mykola Nephrology Fellow

2009 - 2011 2009 - 2011

Mayo Rochester

Assistant Professor Private practice

Glavey, Siobhan Internal Medicine Resident Kattah, Andrea Nephrology Fellow

2010- 2011

University of Ireland Mayo

Fellow in Hematology SAC

Muriithi, Angela Nephrology Fellow Frazee, Erin Pharmacy resident Bhutani, Gauri Nephrology Fellow Safadi, Sami Nephrology Fellow Jaffer Sathick, Insara Nephrology Fellow

2012 2012- 2013 – 2013 – 2014-

Mayo Rochester University of Wisconsin

Private practice Pharmacist Assistant Professor Fellow Fellow

Hamadah, Abdurrahman Nephrology Fellow Gharaibeh, Kamel Nephrology Fellow Higgins, Larissa Internal Medicine Resident Yui, Jennifer Internal Medicine Resident

2014- 2015- 2015 – 2015-

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Salameh, Hassan Nephrology Fellow Manohar, Sandhya Nephrology Fellow

2015 2016

D. Scholarship

Presentations

Memberships

E. Honors and Awards for Education

Teacher of the Year - Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota Top 20% Educator for Resident Education –Department of Medicine Top 20% Educator for Resident Education –Department of Medicine Teacher of the Year - Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota Teacher of the Year – Mayo Fellows’ Association, Division of Nephrology

2004 2010 – 2011 2011 - 2012 2013 2015

F. Academic Career Development

Mayo Quality Fellow – Bronze level 2011

11. INSTITUTIONAL/DEPARTMENTAL ADMINISTRATIVE RESPONSIBILITIES, COMMITTEE MEMBERSHIPS AND OTHER ACTIVITIES

Mayo Clinic

Mayo Clinic Cancer Center

2007 - Present

Mayo Clinic Cancer Center Work Groups Mayo Clinic Cancer Center, Disease/Discipline Oriented Groups (DOG)

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Myeloma, Amyloid, and Dysproteinemia MAD-DOG Member

Institutional Committee on the Use of Gadolinium Based Contrast Agents

Member Mayo Pharmaceutical Formulary Committee

General Medicine/Surgery Task Force Dabigatran Finalized Guidelines

Member

2008 - Present 2011 - present

Mayo Clinic Rochester

Department of Internal Medicine

2007 - Present

Division of Hematology Amyloid Interest Group Member

Medication Use Process Subcommittee

Member

2002 - 2004

Division of Nephrology & Hypertension

Recruitment Committee for Nephrologist Member Recruitment Committee for Transplant Nephrologist Chair

2015 2012

Executive Committee 2009 - 2012 Member

Practice Committee 2009 - 2012

Chair

Nephrology Inpatient Practice Committee 2007 - Present

Member

Recruitment Committee for ICU Nephrologist 2007 Member

Recruitment Committee for Transplant Nephrologist 2007 Member

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Task Force for the Development of Electrolyte Order Set 2003 - 2004 Member

Education Committee

Member 2003 - 2011

Mayo Nephrology Collaborative Group

2002 - Present

Member, Rochester, Minnesota

2002 - 2004

2003 – 2010 2002 – Present

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12. PRESENTATIONS International Light Chain Deposition Disease The XI International Workshop on Multiple Myeloma. Kos, Greece The Serum Free Light Chain Assay- A New Tool in the Diagnosis and Treatment of Paraproteinemia Renal Diseases Australian Clinical Nephrology Symposium. Sydney, Australia Monoclonal Gammopathy and Renal Disease Cours International de Néphrologie, Mayo Clinic College of Medicine Harvard Medical School. Lyon, France Kidney transplantation of patients with paraproteinemia Symposium Fronteras 2010 Santigao, Chile Current treatment of light chain cast nephropathy (myeloma kidney) Symposium Fronteras 2010 Santigao, Chile Amyloidosis Fourth International Congress on Immunosuppression in Nephrology Barcelona, Spain Myeloma Cast Nephropathy 13th International Myeloma Workshop Paris, France Emerging Role of Monoclonal Gammopathy in the Pathogenesis of Kidney Disease Cours International de Néphrologie Médiathèque Paul Zech, Domaine Rockefeller Lyon, France A Case of Nephrotic Syndrome and Renal Failure in an Older Adult with a Monoclonal Gammopathy of Undetermined Significance on Serum Protein Electrophoresis American Society of Nephrology 2012: Kidney Week Advances in Geriatric Nephrology: The Dimitrios G. Oreopoulos Memorial Program Nephrotoxicity of Monoclonal Light Chains 14th International Myeloma Workshop Kyoto, Japan.

06/29/2007 03/09/2008 02/10/2009 05/27/2010 05/29/2010 04/29/2011 05/4/2011 11/16/2012 10/30/2012 04/06/2013

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Monoclonal Gammopathies and Glomerular Diseases The Second International Renal Meeting and Mayo Clinic Day in Sardinia Cagliari, Italy Spectrum of Light Chain-related Disorders ISN World Congress of Nephrology 2013 Hong Kong, China Chemotherapy of Light Chain-related Disorders ISN World Congress of Nephrology 2013 Hong Kong, China Dysproteinemias Onco-Nephrology: What the Nephrologist Needs to Know about Cancer and the Kidney American Society of Nephrology: Kidney Week Atlanta, Georgia Therapeutic Apheresis in Multiple Myeloma: Yea American Society of Nephrology 2013: Kidney Week Atlanta, Georgia Monoclonal gammopathies of renal significance First International Renal Conference Brugge, Belgium Monoclonal gammopathy of renal significance XIV International Society of Amyloidosis: satellite meeting of the IKMG Indianapolis, IN Treatment of Dysproteinemic Renal Disease American Society of Nephrology 2014: Kidney Week Glomerulonephritis Update: Diagnosis and Treatment 2014 Philadelphia, Pennsylvania Clinical Work Up and Treatment of Monoclonal Gammopathy of Renal Significance United States and Canadian Academy of Pathology Annual Meeting 2015 Boston, Massachusetts Treatment of Dysproteinemic Renal Disease The Third International Renal Meeting and Mayo Clinic Day in Sardinia Cagliari, Italy IKMG guide-lines: use of FLC assays The Third International Renal Meeting and Mayo Clinic Day in Sardinia Cagliari, Italy

05/01/2013 06/01/2013 06/01/2013 11/06/2013 11/08/2013 03/21/2014 04/29/2014 11/12/2014 3/22/15 4/30/2015 5/1/2015

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Management of Dysproteinemias American Society of Nephrology 2015: Kidney Week Glomerular Disease Update: Diagnosis and Therapy 2015 San Diego, CA My Patient with MGUS Has a Kidney Problem: What Is This Entity MGRS? American Society of Nephrology 2015 Clinical Practice Sessions San Diego, CA

11/4/2015 11/6/2015

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National Dysproteinemias and the Kidney Collaborate Meeting Mayo Clinic and Norwegian Society of Nephrology 2006. Bergen, Norway Dysproteinemia and the Kidneys Annual Update in Nephrology and Kidney/Pancreas Transplantation Minneapolis, Minnesota Therapeutic Plasma Exchange for Multiple Myeloma-Pro American Society of Apheresis Scottsdale, Arizona Monoclonal IgM and Kidney Diseases International Waldenstrom’s Macroglobulinemia Foundation Minneapolis, Minnesota Monoclonal Gammopathy related Kidney Disease VII Congreso Paraguayo de Nefrologia I Curso de Actualizacion en Nefrologia con la Mayo Clinic, Rochester, Minnesota, U.S.A. IV Congreso de Enfermeria y Tecnicos en Dialisis Asuncion, Paraguay Treatment of Myeloma Cast Nephropathy VII Congreso Paraguayo de Nefrologia I Curso de Actualizacion en Nefrologia con la Mayo Clinic, Rochester, Minnesota, U.S.A. IV Congreso de Enfermeria y Tecnicos en Dialisis Asuncion, Paraguay Monoclonal Gammopathies “of Renal Significance” National Kidney Foundation Spring Meetings 2012 Pre-Conference Courses Glomerular Diseases: Updates on Pathogenesis and Treatment Myeloma and the Kidney The Renal Association Conference 2012 Newcastle Gateshead, United Kingdom Primary Amyloidosis and its Treatment VIII Uruguayan Congress of Nephrology Montevideo, Uroguay

04/23/2006 10/01/2010 06/04/2011 06/25/2011 10/07/2011 10/07/2011 05/09/2012 06/14/2012 09/29/2012

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Treatment with Bortezomib in Multiple Myeloma with Renal Insufficiency VIII Uruguayan Congress of Nephrology Montevideo, Uroguay Emerging role of monoclonal gammopathy in the pathogenesis of kidney disease First Collaborate Meeting of Mayo Clinic College of Medicine and Moroccan Society of Nephrology Casablanca, Morocco Update on dysproteinemia 12th Annual Update Course in Nephrology and Kidney Transplantation Minneapolis, Minnesota Monoclonal Gammopathy of Renal Significance The Royal Society of Medicine Myeloma amyloid London, United Kingdom Renal Complications of BMT- Acute and Chronic 2014 BMT Tandem Meetings Gaylord Texan Convention Center, Grapevine, Texas Nefropatias glomerulares por depósitos organizados de Inmunoglobulinas XXV Curso de Nefrologia de la Fundacio Puigvert Barcelona, Spain Monoclonal Gammopathies Glomerular Diseases: Updates on Pathogenesis and Treatment National Kidney Foundation 2014 Spring Clinical Meetings Las Vegas, Nevada Monoclonal Gammopathy of Renal Significance 19° Convegno Patologia Immue Malattie Orfane Turino, Italy Regional Treatment of Primary Amyloidosis: New Tactics Against An Old Foe Mayo Clinic Rochester Annual Update in Nephrology and Kidney/Pancreas Transplantation. Grand Rapids, Minnesota The Kidney in Dysproteinemia New Diagnostic and Treatment Options Mayo PUCRS 2005 Pontificia Universidade Católica do Rio Gradne do Sul Porto Alegre, Brazil The Kidney in Dysproteinemic States I International Symposium in Nephrology Recife, Brazil

09/29/2012 04/06/2013 09/20/2013 09/26/2013 03/01/2014 04/07/2014 04/22/2014 01/28/16 08/03/2003 04/02/2005 04/05/2005

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Consequences of Liver and Kidney Failure The Council of Nephrology Social Workers of the Upper Midwest and The Minnesota Council on Renal Nutrition Rochester, MN. Rochester, Minnesota Transplantation for patients with myeloma or amyloidosis Mayo Clinic Rochester Annual Update in Nephrology and Kidney/Pancreas Transplantation. Minneapolis, Minnesota Plasma Cell Dyscrasias and Renal Diseases: An Update Seminar of the Hong Kong Society of Nephrology. Hong Kong, China Advances in Diagnosis and Treatment of Paraprotein Related Kidney Disorders Harbor UCLA Medical Center Nephrology Grand Rounds. Los Angeles, California Advances in Diagnosis and Treatment of Paraprotein Related Kidney Disorders Cedars Sinai Medical Center Nephrology Grand Rounds. Los Angeles, California Monoclonal Gammopathy and Renal Diseases Centre Hospitalier Universitaire Vaudois, Lausanne-Genève Meets Mayo Clinic and Harvard Medical School, A Continuous Medical Education Program in Nephrology and Hypertension. Lausanne, Switzerland Kidney Diseases Caused by Dysglobinemias I Symposium Conjuncto Clinica Mayo-Hospital Universitaro Central de Austaurias. Oviedo, Spain Nephrogenic systemic fibrosis Selected Topics in Rheumatology Mayo Clinic, Rochester, Minnesota Paraproteinemias and the kidney: present, past and future. DÉmarches Visant à Enrayer les effets Néfastes de l’Insuffisance Rénale (DEVENIR), 8e Colloque Annuel 2010 Quebec City, Canada Kidney disease caused by dysglobulinemia XXIVth Nephrology Course of the Fundació Puigvert in collaboration with the Mayo Clinic Cagliari, Italy

09/29/2006 09/30/2006 03/12/2008 05/05/2008 05/06/2008 02/05/2009 06/12/2009 05/08/2010 10/16/2010 05/2/2011

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Renal Complications of Multiple Myeloma Vancouver General Hospital University of British Columbia Vancouver, Canada Renal Disorders associated with Plasma Cell Dyscrasias UBC Division of Nephrology City Wide Rounds. St Paul’s Hospital Vancouver, Canada Kidney Transplantation of Patients with Paraproteinemia Program of the 4th Saint-Petersburg Postgraduate Lecture Course in Nephrology “Actual Problems of Nephrology and Dialysis St Petersburg, Russia Current Treatment of Light Chain Cast Nephropathy (Myeloma Kidney) Program of the 4th Saint-Petersburg Postgraduate Lecture Course in Nephrology “Actual Problems of Nephrology and Dialysis” St Petersburg, Russia AL Amyloidosis Program of the 4th Saint-Petersburg Postgraduate Lecture Course in Nephrology “Actual Problems of Nephrology and Dialysis St Petersburg, Russia Update on the Management of Myeloma Cast Nephropathy Updates on Advanced Nephrology Practices Prince of Wales Hospital The Chinese University of Hong Kong Monoclonal Gammopathy of Renal Significance V South Brazilian Congress of Nephrology Gramado, Brazil How to monoclonal gammopathy suspect and diagnosis-related nephropathy V South Brazilian Congress of Nephrology Gramado, Brazil Renal Amyloidosis V South Brazilian Congress of Nephrology Gramado, Brazil Dialysis and Transplantation for Multiple Myeloma Patients V South Brazilian Congress of Nephrology Gramado, Brazil

09/8/2011 09/9/2011 09/16/2011 09/17/2011 09/17/2011 01/14/2012 04/11/2013 04/12/2013 04/12/2013 04/13/2013

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Kidney Disease and Multiple Myeloma (and MGRS) Princess Margaret Hospital Multiple Myeloma Day Toronto, Canada Monoclonal Gammopathy of Renal Significance Cancer Center Grand Rounds Mayo Clinic Scottsdale Monoclonal Gammopathy of Renal Significance Medical Grand Rounds Mayo Clinic Scottsdale Multiple Myeloma Related Renal Impairment in 2014: Treatment Strategies That Optimize Outcomes: An Update on Monoclonal Gammopathy Related Kidney Diseases University of British Columbia Division of Hematology Leukemia/bone Marrow Transplant Program Monoclonal Gammopathy of Renal Significance Joint Mayo Clinic and HK Society of Myeloma Annual Scientific Hong Kong, SAR, China Monoclonal Gammopathy: are there still believers in the MGUS story? Forum Éducationnel pour les Néphrologues Programme Scientifique Foundation DEVENIR Quebec, Canada Paraproteinemic renal diseases: an update The new Paradigm in Monoclonal Gammopathy New York Society of Nephrology New York, New York

06/07/2013 02/27/2014 02/28/2014 06/26/2014 09/13/14 10/19/2014 02/04/15

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13. VISITING PROFESSORSHIPS

University of British Columbia Division of Hematology Leukemia/bone Marrow Transplant Program Galway University Hospital Medical Case Conference Monoclonal Gammopathy of Renal Significance University of Sasketchewan Renal Grand Rounds Regina General Hospital Monoclonal Gammopathy and Kidney Disease Weill Cornell Medical College Nephrology Grand Rounds AL amyloidosis: What can the kidney tell us University of Virgina Nephrology Grand Rounds Advances in Monoclonal Gammopathy of Renal Signficance

09/8/2011-09-09/2001 06/19/2012 06/28/2013 02/04/15 04/05/16

14. CLINICAL PRACTICE, INTERESTS, AND ACCOMPLISHMENTS

Amyloidosis, multiple myeloma, dysproteinemia, kidney transplantation in dysproteinemia, hepatorenal syndrome.

15. RESEARCH INTERESTS

Renal diseases of monoclonal gammopathy of renal significance Toxic nephropathy from chemotherapeutic agents Renal diseases in bone marrow transplant recipients. Thrombotic microangiopathy Chair- Data and Safety Monitoring Board For “A Multicenter, Randomized, Prospective, Open-Label Trial of Rituximab in the Treatment of Progressive IgA Nephropathy” IRB# 07-001944 (2009 to present) Work in Progress: 1. Urinary exosomes: Collaborating with Dr Marina Ramirez-Alvarado to evaluate the potentials of urinary exosomes as a tool for diagnosis and prognosis in patients with paraproteinemia. 2. Diagnostics of low level monoclonal gammopathies

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3. Myeloma Group on clinical trial of plasma exchange in the cast nephropathy 4. Clinical trial for light chain deposition disease without myeloma

16. RESEARCH GRANTS AWARDED

Active Grants Industry Co-Investigator

Mayo Only - A pilot study on the Use of Rituximab or the Treatment of CHURG-STRAUSS Syndrome with renal involvement U3750. Funded by Genentech Incorporated. (U3750s)

11/2006 - 10/2008

Co-Investigator

A Multi-Center Pilot Study to Assess the Safety and Efficacy of A Selective Cytopheretic Device (SCD) In Patients with Acute Renal Failure (ARF). Funded by CytoPherx, Inc. (ARF-002)

01/2010 - 01/2011

Completed Grants Industry Co -Principal Investigator

A Double-Blind, Placebo-Controlled, Randomized Phase III Study of Intravenous Terlipressin in Patients with Hepatorenal Syndrome Type 1. Funded by Orphan Therapeutics. (ORPHAN #5; 1A5601)

12/2004 - 11/2006

Co-Investigator

Government

The Use of Rituximab in the Treatment of Idiopathic Membranous Nephropathy (IRB 627-04). Funded by Genentech Incorporated. (GENENTECH #52; 1A5408) National Institute of Health Training Grant

11/2004 - 10/2009 8/1998 - 6/2000

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Benefactor gifts

Dr. Gary K. Kohler and Mrs. Anne S. Drennan $50,000 Mr. Terry L. Blackert $50 Mr. Glenn W. Belsley $70 Mr. and Mrs. T. Kirshenbaum $49,119.38 Mr. and Mrs. David B. Kirshenbaum Ted and Jordan Kirshenbaum Families $15,000

03/14/14 06/05/14 06/20/14 01/09/15 03/02/15

Ms. April D. Nelson $25

11/02/15

17. PATENTS

Title Patent number Date filed Date issued

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18. BIBLIOGRAPHY

Original Peer-reviewed Articles

1. Leung N, Barnidge DR, Hutchison CA. Laboratory testing in monoclonal gammopathy of

renal significance (MGRS). Clin Chem Lab Med. 2016; 54: 929-37.

2. Mullikin TC, Rajkumar SV, Dispenzieri A, Buadi FK, Lacy MQ, Lin Y, Dingli D, Go RS, Hayman SR, Zeldenrust SR, Russell SJ, Lust JA, Leung N, Kapoor P, Kyle RA, Gertz, MA, Kumar, SK. Clinical characteristics and outcomes in biclonal gammopathies. Am J Hematol. 2016; 91: 473-5.

3. Kourelis TV, Buadi FK, Gertz MA Lacy MQ, Kumar SK, Kapoor P, Go RS, Lust JA, Hayman, SR, Rajkumar V, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Leung N, Hwa YL, Gonsalves W, Kyle RA, Dispenzieri A. Risk factors for and outcomes of patients with POEMS syndrome who experience progression after first-line treatment. Leukemia 2016; 30: 1079-85.

4. Gonsalves WI, Timm MM, Rajkumar SV, Morice WG, Dispenzieri A, Buadi FK, Lacy, MQ, Dingli D, Leung N, Kapoor P, Kyle RA, Gertz MA, Kumar SK. The prognostic significance of CD45 expression by clonal bone marrow plasma cells in patients with newly diagnosed multiple myeloma. Leukemia Research. 2016; 44: 32-9.

5. Dimopoulos MA, Sonneveld P, Leung N, Merlini G, Ludwig H, Kastritis E, Goldschmidt,

H, Joshua D, Orlowski RZ, Powles R, Vesole DH, Garderet L, Einsele H, Palumbo A, Cavo M, Richardson PG, Moreau P, San Miguel J, Rajkumar SV, Durie BGM, Terpos E. International Myeloma Working Group Recommendations for the Diagnosis and Management of Myeloma-Related Renal Impairment. J Clin Oncol. 2016. 34: 1054-

6. Sethi S, Haas M, Markowitz GS, D'Agati VD, Rennke HG, Jennette JC, Bajema IM, Alpers

CE, Chang A, Cornell LD, Cosio FG, Fogo AB, Glassock RJ, Hariharan S, Kambham N, Lager DJ, Leung N, Mengel M, Nath KA, Roberts IS, Rovin BH, Seshan SV, Smith RJ, Walker PD, Winearls CG, Appel GB, Alexander MP, Cattran DC, Casado CA, Cook HT, De Vriese AS, Radhakrishnan J, Racusen LC, Ronco P, Fervenza FC. Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN. J Am Soc Nephrol. 2015;

7. Nasr SH, Collins AB, Alexander MP, Schraith DF, Hernandez LH, Fidler ME, Sethi, S,

Leung N, Fervenza FC, Cornell, LD. The clinicopathologic characteristics and outcome of atypical anti-glomerular basement membrane nephritis. Kidney Int. 2016; 89: 897-908.

8. Binder M, Rajkumar SV, Ketterling RP, Dispenzieri A, Lacy MQ, Gertz MA, Buadi FK, Hayman SR, Hwa YL, Zeldenrust SR, Lust JA, Russell SJ, Leung N, Kapoor P, Go RS, Gonsalves WI, Kyle RA, Kumar SK. Occurrence and prognostic significance of cytogenetic evolution in patients with multiple myeloma. Blood Cancer J. 2016; 6: e401.

9. Zand L, Nasr SH, Gertz MA, Dispenzieri A, Lacy MQ, Buadi FK, Kumar S, Kyle RA,

Fervenza FC, Sethi S, Dingli D, Rajkumar SV, Kapoor P, McCurdy A, Leung N. Clinical and prognostic differences among patients with light chain deposition disease, myeloma cast nephropathy and both. Leuk Lymphoma. 2015; 56: 3357-64.

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10. Strati P, Nasr SH, Leung N, Hanson CA, Chaffee KG, Schwager SM, Achenbach SJ, Call

TG, Parikh SA, Ding W, Kay NE, Shanafelt TD. Renal complications in chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis: the Mayo Clinic experience. Haematologica. 2015; 9: 1180-8.

11. Dispenzieri A, Buadi F, Kumar SK, Reeder CB, Sher T, Lacy MQ, Kyle RA, Mikhael JR,

Roy V, Leung N, Grogan M, Kapoor P, Lust JA, Dingli D, Go RS, Hwa YL, Hayman SR, Fonseca R, Ailawadhi S, Bergsagel PL, Chanan-Khan A, Rajkumar SV, Russell SJ, Stewart K, Zeldenrust SR, Gertz, MA Treatment of Immunoglobulin Light Chain Amyloidosis: Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Statement. Mayo Clin Proc. 2015; 90: 1054-81.

12. Safadi S. Saad A, Quint PS, Sethi S, Leung N, Kurtin P, Nasr SH. Disappearance of

immunoglobulins from persistent renal amyloid deposits following stem cell transplantation for heavy-and light-chain amyloidosis. Nephrol Dial Transplant. 2015; 30; 1151-5.

13. Dispenzieri A, Gertz MA, Saenger A, Kumar SK, Lacy MQ, Buadi FK, Dingli D, Leung

N, Zeldenrust S, Hayman SR, Kapoor P, Grogan M, Hwa L, Russell SJ, Go RS, Rajkumar SV, Kyle RA, Jaffe A. Soluble suppression of tumorigenicity 2 (sST2), but not galactin-3, adds to prognostication in patients with systemic AL amyloidosis independent of NT-proBNP and troponin T. Am J Hematol. 2015; 90: 524-8.

14. Nasr SH, Shanafelt TD, Hanson CA, Fidler ME, Cornell LD, Sethi S, Chaffee KG, Morris

J, Leung N. Granulomatous interstitial nephritis secondary to chronic lymphocytic leukemia/small lymphocytic lymphoma. Ann Diagnostic Pathol. 2015; 19: 130-6.

15. Warsame R, Kumar SK, Gertz MA, Lacy MQ, Buadi FK, Hayman SR, Leung N, Dingli D,

Lust JA, Ketterling RP, Lin Y, Russell S, Hwa L, Kapoor P, Go RS, Zeldenrust SR, Kyle RA, Rajkumar SV, Dispenzieri A. Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death. Blood Cancer J. 2015; 5:e310. Epub 2015

16. Bhutani G, Nasr SH, Said SM, Sethi S, Fervenza FC, Morice WG, Kurtin PJ, Buadi FK,

Dingli D, Dispenzieri A, Gertz MA, Lacy MQ, Kapoor P, Kumar S, Kyle RA, Rajkumar SV, Leung N. Hematologic characteristics of proliferative glomerulonephritides with nonorganized monoclonal immunoglobulin deposits. Mayo Clin Proc. 2015; 90: 587-96.

17. Yadav P, Leung N, Sanders PW, Cockwell P. The use of immunoglobulin light chain

assays in the diagnosis of paraprotein-related kidney disease. Kidney Int. 2015; 87: 692-7. 18. Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM,

Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH. Diagnosis of monoclonal gammopathy of renal significance. Kidney Int. 2015; 87: 698-711.

19. Gonsalves WI, Leung N, Rajkumar SV, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK,

Dingli D, Kapoor P, Go RS, Lin Y, Russell SJ, Lust, JA, Zeldenrust S, Kyle RA, Gertz MA, Kumar SK. Improvement in renal function and its impact on survival in patients with newly diagnosed multiple myeloma. Blood Cancer J. 2015; 5:

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20. Kaufman GP, Dispenzieri A, Gertz MA, Lacy MQ, Buadi FK, Hayman SR, Leung N,

Dingli D, Lust JA, Lin Y, Kapoor P, Go RS, Zeldenrust SR, Kyle RA, Rajkumar SV, Kumar SK. Kinetics of organ response and survival following normalization of the serum free light chain ratio in AL amyloidosis. Am J Hematol. 2015; 90: 181-5.

21. Muriithi AK, Leung N, Valeri AM, Cornell LD, Sethi S, Fidle ME, Nasr SH. Clinical

characteristics, causes and outcomes of acute interstitial nephritis in the elderly. Kidney Int. 2015; 87: 458 – 64.

22. Fervenza FC, Canetta PA, Barbour SJ, Lafayette RA, Rovin BH, Aslam N, Hladunewich

MA, Irazabal MV, Sethi S, Gipson DS, Reich HN, Brenchley P, Kretzler M, Radhakrishnan J, Hebert LA, Gipson PE, Thomas LF, McCarthy ET, Appel GB, Jefferson JA, Eirin A, Lieske JC, Hogan MC, Greene EL, Dillon JJ, Leung N, Sedor JR, Rizk DV, Blumenthal SS, Lasic LB, Juncos LA, Green DF, Simon J, Sussman AN, Philibert D, Cattran, DC. A Multicenter Randomized Controlled Trial of Rituximab versus Cyclosporine in the Treatment of Idiopathic Membranous Nephropathy (MENTOR). Nephron. 2015; 130: 159-68.

23. Safadi S, Dispenzieri A, Amer H, Gertz MA, Rajkumar SV, Hayman SR, Lacy, MQ,

Leung, N. Multiple myeloma after kidney transplantation. Clin Transplant. 2015; 29: 76-84.

24. Jimenez-Zepeda VH, Leung N. ALECT2 amyloidosis: A new type of systemic amyloid

highly prevalent in the Hispanic population. Rev Invest Clin. 2014; 66: 269-73. 25. Kourelis TV, Kumar SK, Go RS, Kapoor P, Kyle RA, Buadi FK, Gertz MA, Lacy MQ,

Hayman SR, Leung N, Dingli D, Lust JA, Lin Y, Zeldenrust SR, Rajkumar SV, Dispenzieri A. Immunoglobulin light chain amyloidosis is diagnosed late in patients with preexisting plasma cell dyscrasias. Am J Hematol. 2014; 89: 1051-4.

26. Frazee EN, Rule AD, Herrmann SM, Kashani KB, Leung N, Virk A, Voskoboev N, Lieske

JC. Serum cystatin C predicts vancomycin trough levels better than serum creatinine in hospitalized patients: A cohort study. Crit Care. 2014; 18: R110.

27. Muriithi AK, Leung N, Valeri AM, Cornell LD, Sethi S, Fidler ME, Nasr SH. Biopsy-

Proven Acute Interstitial Nephritis, 1993-2011: A Case Series. Am J Kidney Dis. 2014; 64: 558-66.

28. Said SM, Sethi S, Valeri AM, Chang A, Nast CC, Krahl L, Molloy P, Barry M, Fidler ME,

Cornell LD, Leung N, Vrana JA, Theis JD, Dogan A, Nasr SH. Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis. Kidney Int. 2014; 86: 370-7.

29. Hladunewich MA, Cattran D, Beck LH, Odutayo A, Sethi S, Ayalon R, Leung N, Reich H,

Fervenza, FC. A pilot study to determine the dose and effectiveness of adrenocorticotrophic hormone (HP ActharA (R) Gel) in nephrotic syndrome due to idiopathic membranous nephropathy. Nephrol Dial Transplant. 2014; 29: 1570-7.

30. Russell SJ, Federspiel MJ, Peng KW, Tong CL, Dingli D, Morice WG, Lowe V, O'Connor

MK, Kyle RA, Leung N, Buadi FK, Rajkumar SV, Gertz MA, Lacy MQ, Dispenzieri A.

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Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy. Mayo Clin Proc 2014; 89: 926-33.

31. Warsame R, Bang SM, Kumar SK, Gertz MA, Lacy MQ, Buadi F, Dingli D, Hayman SR,

Kapoor P, Kyle RA, Leung N, Lust JA, Russell SJ, Witzig TE, Zeldenrust SR, Rajkumar SV, Dispenzieri A. Outcomes and treatments of patients with immunoglobulin light chain amyloidosis who progress or relapse postautologous stem cell transplant. Eur J of Haematol. 2014; 92: 485-90.

32. Kumar SK, Dispenzieri A, Lacy MQ, Gertz MA, Buadi FK, Pandey S, Kapoor P, Dingli D,

Hayman SR, Leung N, Lust J, McCurdy A, Russell SJ, Zeldenrust SR, Kyle RA, Rajkumar, SV. Continued improvement in survival in multiple myeloma: changes in early mortality and outcomes in older patients. Leukemia. 2014; 28: 1122-8.

33. Kourelis TV, Kumar SK, Srivastava G, Gertz MA, Lacy MQ, Buadi FK, Hayman SR,

Zeldenrust SR, Leung N, Kyle RA. Long-term disease control in patients with newly diagnosed multiple myeloma after suspension of lenalidomide therapy. Am J Hematol. 2014; 89: 302-5.

34. Dispenzieri A, Gertz MA, Kumar SK, Lacy MQ, Kyle RA, Saenger AK, Grogan M,

Zeldenrust SR,Hayman SR, Buadi F, Greipp PR, Leung N, Russell SR, Dingli D, Lust JA, Rajkumar SV, Jaffe AS. High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis. Heart. 2014; 100: 383-8.

35. Kapoor P, Kumar SK, Dispenzieri A, Lacy MQ, Buadi F, Dingli D, Russell SJ, Hayman,

SR, Witzig TE, Lust JA, Leung N, Lin Y, Zeldenrust SR, McCurdy A, Greipp PR, Kyle RA, Rajkumar SV, Gertz MA. Importance of Achieving Stringent Complete Response After Autologous Stem-Cell Transplantation in Multiple Myeloma. J Clin Oncol. 2013; 31: 4529-35.

36. Dispenzieri A, Stewart AK, Chanan-Khan A, Rajkumar SV, Kyle RA, Fonseca R, Kapoor

P, Bergsagel PL, McCurdy A, Gertz MA, Lacy MQ, Lust JA, Russell SJ, Zeldenrust, SR, Reeder C, Roy V, Buadi F, Dingli D, Hayman SR, Leung, N, Lin, Y, Mikhael, J, Kumar SK. Smoldering multiple myeloma requiring treatment: time for a new definition? Blood. 2013; 122: 4172-81.

37. Kourelis TV, Kumar SK, Gertz MA, Lacy MQ, Buadi, FK, Hayman SR, Zeldenrust S,

Leung N, Kyle RA, Russell S, Dingli D, Lust JA, Lin Y, Kapoor P, Rajkumar SV, McCurdy A, Dispenzieri A. Coexistent Multiple Myeloma or Increased Bone Marrow Plasma Cells Define Equally High-Risk Populations in Patients with Immunoglobulin Light Chain Amyloidosis. J Clin Oncol. 2013; 31: 4319-24.

38. Fermand JP, Bridoux F, Kyle RA, Kastritis E, Weiss BM, Cook MA, Drayson MT,

Dispenzieri A, Leung, N. How I treat monoclonal gammopathy of renal significance (MGRS). Blood. 2013; 122: 3583-90.

39. Muriithi AK, Nasr SH, Leung N. Utility of Urine Eosinophils in the Diagnosis of Acute

Interstitial Nephritis. Clin J Am Soc Nephrol. 2013; 8: 1857-62. 40. Glavey SV, Gertz MA, Dispenzieri A, Kumar S, Buadi F, Lacy M, Hayman SR, Kapoor P,

Dingli D, McCurdy A, Hogan WJ, Gastineau DA, Leung, N. Long-term outcome of

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patients with multiple myeloma-related advanced renal failure following auto-SCT. Bone Marrow Transplant. 2013; 48: 1543-7.

41. Said SM, Sethi S, Valeri AM, Leung N, Cornell LD, Fidler ME, Hernandez LH, Vrana

JA, Theis JD, Quint, PS, Dogan A, Nasr SH. Renal Amyloidosis: Origin and Clinicopathologic Correlations of 474 Recent Cases. Clin J Am Soc Nephrol. 2013; 8: 1515-23.

42. Zand L, Kattah A, Fervenza FC, Smith RJ, Nasr SH, Zhang Y, Vrana JA, Leung N,

Cornell LD, Sethi S. C3 Glomerulonephritis Associated With Monoclonal Gammopathy: A Case Series. Am J Kidney Dis. 2013.

43. Humeniuk MS, Gertz MA, Lacy MQ, Kyle RA, Witzig TE, Kumar SK, Kapoor P, Lust JA,

Hayman SR, Buadi FK, Rajkumar SV, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Leung N, Dispenzieri A. Outcomes of patients with POEMS syndrome treated initially with radiation. Blood. 2013; 122: 68-73.

44. Leung N, Glavey SV, Kumar S, Dispenzieri A, Buadi FK, Dingli D, Lacy MQ, Hayman

SR, Lust JA, Russell SJ, Zeldenrust SR, Rajkumar SV, Gertz MA. A detailed evaluation of the current renal response criteria in AL amyloidosis: Is it time for a revision? Haematologica. 2013; 98: 988-92.

45. Sethi S, Theis JD, Vrana JA, Fervenza FC, Sethi A, Qian Q, Quint P, Leung N, Dogan A,

Nasr SH. Laser Microdissection and Proteomic Analysis of Amyloidosis, Cryoglobulinemic GN, Fibrillary GN, and Immunotactoid Glomerulopathy. Clin J Am Soc Nephrol. 2013; 8: 915-21.

46. Kourelis TV, Gertz M, Zent C, Lacy M, Kyle R, Kapoor P, Zeldenrust S, Buadi F, Witzig

T, Hayman S, Lust J, Russell S, Lin Y, Rajkuma, VS, Kumar S, Leung, N, Dingli D, Dispenzieri A. Systemic amyloidosis associated with chronic lymphocytic leukemia/small lymphocytic lymphoma. Am J Hematol. 2013; 89: 275-8.

47. Mikhael JR, Dingli D, Roy V, Reeder CB, Buadi FK, Hayman SR, Dispenzieri A, Fonseca

R, Sher T, Kyle RA, Lin Y, Russell SJ, Kumar S, Bergsagel PL, Zeldenrust SR, Leung N, Drake MT, Kapoor P, Ansell SM, Witzig TE, Lust JA, Dalton RJ, Gertz MA, Stewart K, Rajkumar SV, Chanan-Khan A, Lacy MQ. Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013. Mayo Clin Proc. 2013; 88: 360-76.

48. Gertz MA, Lacy MQ, Dispenzieri A, Kumar SK, Dingli D, Leung N, Hogan WJ, Buadi

FK, Hayman SR. Refinement in patient selection to reduce treatment-related mortality from autologous stem cell transplantation in amyloidosis. Bone Marrow Transplant 2013; 48: 557-61.

49. Nasr SH, Said SM, Valeri AM, Sethi S, Fidler ME, Cornell LD, Gertz MA, Dispenzieri A,

Buadi FK, Vrana JA, Theis JD, Dogan A, Leung N. The diagnosis and characteristics of renal heavy-chain and heavy/light-chain amyloidosis and their comparison with renal light-chain amyloidosis. Kidney Int. 2013; 83: 463-70.

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50. Irazabal MV, Eirin A, Lieske J, Beck LH, Sethi S, Borland TM, Dillon JJ, Nachman PH, Nasr SH, Cornell LD, Leung N, Cattran DC, Fervenza FC. Low- and high-molecular-weight urinary proteins as predictors of response to rituximab in patients with membranous nephropathy: a prospective study. Nephrol Dial Transplant. 2012; 28: 137-46.

51. Leung N, Gertz M, Kyle RA, Fervenza FC, Irazabal MV, Eirin A, Kumar S, Cha SS,

Rajkumar SV, Lacy MQ, Zeldenrust SR, Buadi FK, Hayman SR, Nasr SH, Sethi S, Ramirez-Alvarado M, Witzig TE, Herrmann SM, Dispenzieri A. Urinary Albumin Excretion Patterns of Patients with Cast Nephropathy and Other Monoclonal Gammopathy-Related Kidney Diseases. Clin J Am Soc Nephrol. 2012; 7: 1964-8.

52. Frazee EN, Kuper PJ, Schramm GE, Larson SL, Kashani KB, Osmon DR, Leung N. Effect

of Continuous Venovenous Hemofiltration Dose on the Achievement of Adequate Vancomycin Trough Concentrations. Antimicrob Agents Chemother. 2012; 56: 6181-5.

53. Leung N, Bridoux F, Hutchison CA, Nasr SH, Cockwell P, Fermand JP, Dispenzieri A,

Song KW, Kyle RA. Monoclonal gammopathy of renal significance (MGRS): when MGUS is no longer undetermined or insignificant. Blood. 2012; 120: 4292-5.

54. Nasr SH, Fidler ME , Cornell LD, Leung N, Cosio FG, Sheikh SS, Amir AA, Vrana JA,

Theis JD, Dogan A, Sethi, S. Immunotactoid glomerulopathy: clinicopathologic and proteomic study. Nephrol Dial Transplant. 2012; 27: 4137-46.

55. Leung N, Nasr S, Sethi S. How I treat amyloidosis: the importance of accurate diagnosis

and amyloid typing. Blood. 2012; 120: 3206-13. 56. Hayman SR, Leung N, Grande JP, Garovic VD. VEGF Inhibition, Hypertension, and

Renal Toxicity. Curr Oncol Reports. 2012; 14: 285-294. 57. Sethi S, Vrana1 JA, Theis JD, Leung N, Sethi A, Nasr SH, Fervenza FC, Cornell LD,

Fidler ME, Dogan A. Laser microdissection and mass spectrometry–based proteomics aids the diagnosis and typing of renal amyloidosis. Kidney Int. 2012; 82: 226-34

58. Warsame R, Gertz MA, Lacy MQ, Kyle RA, Buadi F, Dingli D, Greipp PR, Hayman SR,

Kumar SK, Lust JA, Russell SJ, Witzig TE, Mikhael J, Leung N, Zeldenrust SR, Rajkumar SV Dispenzieri A. Trends and outcomes of modern staging of solitary plasmacytoma of bone. Am J Hematol. 2012; 87: 647-51.

59. Ramirez-Alvarado M, Ward CJ, Huang BQ, Gong X, Hogan MC, Madden BJ,

Charlesworth MC, Leung N. Differences in Immunoglobulin Light Chain Species Found in Urinary Exosomes in Light Chain Amyloidosis (AL). PLoS ONE 7(6): e38061. 2012.

60. Nasr SH, Valeri AM, Sethi S, Fidler ME, Cornell LD, Gertz MA, Lacy M, Dispenzieri A,

Rajkumar SV, Kyle RA, Leung N. Clinicopathologic Correlations in Multiple Myeloma: A Case Series of 190 Patients With Kidney Biopsies. Am J Kidney Dis. 2012; 59: 786-94.

61. Hutchison CA, Blade J, Cockwell P, Cook M, Drayson M, Fermand JP, Kastritis E, Kyle R,

Leung N, Pasquali S, Winearls C. Novel approaches for reducing free light chains in patients with myeloma kidney. Nat Rev Nephrol. 2012; 8: 234-43.

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62. Kumar S, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Colby C, Laumann K,

Zeldenrust SR, Leung N, Dingli D, Greipp PR, Lust JA, Russell SJ, Kyle RA, Rajkumar SV, Gertz MA. Revised Prognostic Staging System for Light Chain Amyloidosis Incorporating Cardiac Biomarkers and Serum Free Light Chain Measurements. J Clin Oncol. 2012; 989-95.

63. Kumar SK, Lacy MQ, Dispenzieri A, Buadi FK, Hayman SR, Dingli D, Gay F, Sinha S,

Leung N, Hogan W, Rajkumar SV, Gertz MA. Early versus delayed autologous transplantation after immunomodulatory agents-based induction therapy in patients with newly diagnosed multiple myeloma. Cancer. 2012; 118: 1585-92.

64. Eirin A, Irazabal MV, Gertz MA, Dispenzieri A, Lacy MQ, Kumar S, Sethi S, Nasr SH,

Cornell LD, Fidler ME, Fervenza FC, Leung N. Clinical features of patients with immunoglobulin light chain amyloidosis (AL) with vascular-limited deposition in the kidney. Nephrol Dial Transplant. 2012; 27: 1097-1101.

65. Madan S, Kumar SK, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Dingli D,

Rajkumar SV, Hogan WJ, Leung N, Grogan M, Gertz MA. High-dose melphalan and peripheral blood stem cell transplantation for light-chain amyloidosis with cardiac involvement. Blood. 2012; 119; 1117-22.

66. Nasr SH, Valeri AM, Cornell LD, Fidler ME, Sethi S, D'Agati VD, Leung N. Renal

Monoclonal Immunoglobulin Deposition Disease: A Report of 64 Patients from a Single Institution. Clin J Am Soc Neph 2012; 7: 231-9.

67. Gertz MA, Buadi FK, Hayman SR, Dingli D, Dispenzieri A, Greipp PR, Kumar SK, Lacy

MQ, Lust JA , Leung N, Rajkumar SV, Russell SJ, Zeldenrust SR, Mikhael JR, Roy V, Kyle RA. Immunoglobulin D amyloidosis: a distinct entity. Blood. 2012; 119; 44-48.

68. Naina HVK, Harris S, Dispenzieri A, Cosio FG, Habermann TM, Stegall MD, Dean PG,

Prieto M, Kyle RA, Rajkumar SV, Leung N. Long-Term Follow-Up of Patients with Monoclonal Gammopathy of Undetermined Significance after Kidney Transplantation. Am J Nephrol. 2012; 35: 365-71.

69. Irazabal MV, Eirin A, Gertz MA, Dispenzieri A, Kumar S, Buadi FK, Lacy MQ, Hayman

SR, Dingli D, Hogan WJ, Gastineau DA, Glavey SV, Amer H, Leung N. Acute kidney injury during leukocyte engraftment after autologous stem cell transplantation in patients with light-chain amyloidosis. Am J Hematol. 2012; 87: 51-4.

70. Clapp AJ, Lee, CU, Wood-Wentz CM, Leung N, Dispenzieri A. Imaging Evidence for

Renomegaly in Patients with POEMS Syndrome. Acad Radiol. 2011; 1241-4. 71. Said SM, Leung N, Sethi S, Cornell LD, Fidler ME, Grande JP, Herrmann S, Tefferi A,

D’Agati VD, Nasr SH. Myeloproliferative neoplasms cause glomerulopathy. Kidney Int. 2011; 80: 753-9.

72. Gertz, MA, Gastineau, DA, Lacy, MQ, Dispenzieri, A, Hayman, SR, Kumar, SK, Dingli,

D, Leung N, Wolf, RC, Hogan, WJ, Buadi, FK. SCT without growth factor in multiple myeloma: engraftment kinetics, bacteremia and hospitalization. Bone Marrow Transplant. 2011; 46: 956-61.

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73. Gertz MA, Lacy MQ, Dispenzieri A, Kumar SK, Buadi FK, Dingli D, Leung N, Hogan

WJ and Hayman SR. Trends in day 100 and 2-year survival after auto-SCT for AL amyloidosis: outcomes before and after 2006. Bone Marrow Transplantation. 2011; 46: 970-5.

74. Hutchison CA, Cockwell P, Stringer S, Bradwell A, Cook M, Gertz MA, Dispenzieri A,

Winters JL, Kumar S, Rajkumar SV, Kyle RA, Leung N. Early Reduction of Serum-Free Light Chains Associates with Renal Recovery in Myeloma Kidney. J Am Soc Neph. 2011; 22: 1129-36.

75. Herrmann SM, Gertz MA, Stegall MD, Dispenzieri A, Cosio FC, Kumar S, Lacy MQ,

Dean PG, Prieto M, Zeldenrust SR, Buadi FK, Russell SJ, Nyberg SL, Hayman SR, Dingli D, Fervenza FC, Leung N. Long-term outcomes of patients with light chain amyloidosis (AL) after renal transplantation with or without stem cell transplantation. Nephrol Dial Transplant. 2011; 26: 2032-6.

76. Sethi S, Fervenza FC, Zhang Y, Nasr SH, Leung N, Vrana J, Cramer C, Nester CM, Smith

RJH. Proliferative Glomerulonephritis Secondary to Dysfunction of the Alternative Pathway of Complement. Clin J Am Soc Neph. 2011; 6: 1009-17.

77. Nasr SH, Valeri AM, Cornell LD, Fidler ME, Sethi S, Leung N, Fervenza FC. Fibrillary

Glomerulonephritis: A Report of 66 Cases from a Single Institution. Clin J Am Soc Neph 2011; 6: 775-84.

78. Kumar SK, Dispenzieri A, Lacy MQ, Hayman SR, Buadi FK, Zeldenrust SR, Tan T, Sinha

S, Leung N, Kyle RA, Rajkumar SV, Gertz MA. Changes in serum-free light chain rather than intact monoclonal immunoglobulin levels predicts outcome following therapy in primary amyloidosis. Am J Hematol. 2011; 86: 251-5.

79. Christensen KN, Lee CU, Hanley MM, Leung N, Moyer TP, Pittelkow MR.

Quantification of gadolinium in fresh skin and serum samples from patients with nephrogenic systemic fibrosis. J Am Acad Dermatol. 2011; 64: 91-6.

80. Kumar SK, Gertz MA, Lacy MQ, Dingli D, Hayman SR, Buadi FK, Short-Detweiler K,

Zeldenrust SR, Leung N, Greipp PR, Lust JA, Russell SJ, Kyle RA, Rajkumar SV, Dispenzieri A. Recent Improvements in Survival in Primary Systemic Amyloidosis and the Importance of an Early Mortality Risk Score. Mayo Clinic Proc. 2011; 86:12-8.

81. Kumar S, Dispenzieri A, Katzmann JA, Larson DR, Colby CL, Lacy MQ, Hayman SR,

Buadi FK, Leung N, Zeldenrust SR, Ramirez-Alvarado M, Clark RJ, Kyle RA, Rajkumar SV, Gertz, MA. Serum immunoglobulin free light-chain measurement in primary amyloidosis: prognostic value and correlations with clinical features. Blood. 2010; 116: 5126-9.

82. Sethi S, Theis JD, Leung N, Dispenzieri A, Nasr SH, Fidler ME, Cornell LD, Gamez JD,

Vrana JA, Dogan A. Mass Spectrometry-Based Proteomic Diagnosis of Renal Immunoglobulin Heavy Chain Amyloidosis. Clin J Am Soc Neph 2010; 5: 2180-7.

83. Fervenza FC, Abraham RS, Erickson SB, Irazabal MV, Eirin A, Specks U, Nachman PH,

Bergstralh EJ, Leung N, Cosio FG, Hogan MC, Dillon JJ, Hickson LJ, Li X, Cattran DC.

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Rituximab Therapy in Idiopathic Membranous Nephropathy: A 2-Year Study. Clin J Am Soc Neph 2010; 5: 2188-98.

84. Dimopoulos MA, Terpos E, Chanan-Khan A, Leung N, Ludwig H, Jagannath S, Niesvizky

R, Giralt S, Fermand JP, Blade J, Comenzo RL, Sezer O, Palumbo A, Harousseau JL, Richardson PG, Barlogie B, Anderson KC, Sonneveld P, Tosi P, Rajkumar SV, Durie BG, San Miguel J. Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group. J Clin Oncol. 2010; 23: 4976-4984.

85. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Dingli D, Ansell SM,

Gastineau DA, Inwards DJ, Johnston PB, Litzow MR, Micallef INM, Porrata LF, Leung N, Hogan WJ, Buadi FK. Autologous stem cell transplant for immunoglobulin light chain amyloidosis: a status report. Leukemia & Lymphoma. 2010; 51: 2181-7.

86. Dispenzieri A, Dingli D, Kumar SK, Rajkumar SV, Lacy MQ, Hayman S, Buadi F,

Zeldenrust S, Leung N, Detweiler-Short K, Lust JA, Russell SJ, Kyle RA, Gertz MA. Discordance between serum cardiac biomarker and immunoglobulin-free light-chain response in patients with immunoglobulin light-chain amyloidosis treated with immune modulatory drugs. Am J Hematol 2010; 85: 757-9.

87. Stankowski-Drengler T, Gertz MA, Katzmann JA, Lacy MQ, Kumar S, Leung N, Hayman

SR, Buadi F, Kyle RA, Rajkumar SV, Dispenzieri A. Serum immunoglobulin free light chain measurements and heavy chain isotype usage provide insight into disease biology in patients with POEMS syndrome. Am J Hematol 2010; 85: 431-4.

88. Sethi S, Zand L, Leung N, Smith RJH, Jevremonic D, Herrmann SS, Fervenza FC.

Membranoproliferative Glomerulonephritis Secondary to Monoclonal Gammopathy. Clin J Am Soc Neph 2010; 5: 770-82.

89. Lorenz EC, Sethi S, Leung N, Dispenzieri A, Fervenza FC and Cosio FG. Recurrent

membranoproliferative glomerulonephritis after kidney transplantation. Kidney Int. 2010; 77: 721-8.

90. Leung N, Shaikh A, Cosio FG, Griffin MD, Textor SC, Gloor JM, Schwab TR, Larson TS,

Dean PG, Prieto M, Nyberg SL, Stegall MD, Lee CU, Pittelkow MR. The outcome of patients with nephrogenic systemic fibrosis after successful kidney transplantation. Am J Transplant. 2010; 10: 558-62.

91. Silva F, Specks U, Kalra S, Hogan MC, Leung N, Sethi S, Fervenza FC. Mycophenolate

Mofetil for Induction and Maintenance of Remission in Microscopic Polyangiitis with Mild to Moderate Renal Involvement—A Prospective, Open-Label Pilot Trial. Clin J Am Soc Neph 2010; 5: 445-53.

92. Lee CU, Wood CM, Hesley GK, Leung N, Bridges MD, Lund JT, Lee PU, Pittelkow MR.

Large sample of nephrogenic systemic fibrosis cases from a single institution. Arch Derm 2009; 145: 1095-102.

93. Gertz MA, Leung N, Lacy MQ, Dispenzieri A, Zeldenrust SR, Hayman SR, Buadi FK,.

Dingli D, Greipp PR, Kumar SK, Lust JA, Rajkumar SV, Russell SJ, Witzig TE. Clinical

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outcome of immunoglobulin light chain amyloidosis affecting the kidney. Nephrol Dial Transplant 2009; 24: 3132-7.

94. Poshusta TL, Sikkink LA, Leung N, Clark RJ, Dispenzieri A, Ramirez-Alvarado M.

Mutations in Specific Structural Regions of Immunoglobulin Light Chains Are Associated with Free Light Chain Levels in Patients with AL Amyloidosis. PLoS ONE. 2009; 4(4):e5169. doi:10.1371/journal.pone.0005169

95. Awan FT, Kay NE, Davis ME, Wu W, Geyer SM, Leung N, Jelinek DF, Tschumper RC,

Secreto CR, Lin TS, Grever MR, Shanafelt TD, Zent CS, Call TG, Heerema NA, Lozanski G, Byrd JC and Lucas DM. Mcl-1 expression predicts progression-free survival in chronic lymphocytic leukemia patients treated with pentostatin, cyclophosphamide, and rituximab. Blood. 2009; 113: 535-7.

96. Czarnecki PG, Lager DJ, Leung N, Dispenzieri A, Cosio FG and Fervenza FC. Long-term

outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits. Kidney Int. 2009; 75: 420-7.

97. Gertz MA, Ansell SM, Dingli D, Dispenzieri A, Buadi FK, Elliott MA, Gastineau DA,

Hayman SR, Hogan WJ, Inwards DJ, Johnston PB, Kumar S, Lacy MQ, Leung N, Micallef INM, Porrata LF, Schafer BA, Wolf RC, Litzow MR. Autologous stem cell transplant in 716 patients with multiple myeloma: Low treatment-related mortality, feasibility of outpatient transplant, and effect of a multidisciplinary quality initiative. Mayo Clin Proc. 2008; 83: 1131-35.

98. Soares SM, Fervenza FC, Lager DJ, Gertz MA, Cosio FC and Leung N. Bleeding

complications after transcutaneous renal biopsy in patients with systemic amyloidosis: Single-center experience in 101 patients. Am J Kidney Dis. 2008; 52; 1079-83.

99. Lorenz EC, Gertz MA, Fervenza FC, Dispenzieri A, Lacy MQ, Hayman SR, Gastineau

DA, Leung N. Long-term outcome of autologous stem cell transplantation in light chain deposition disease. Nephrol Dial Transplant 2008; 23: 2052-7.

100. Leung N, Gertz MA, Zeldenrust SR, Rajkumar SV, Dispenzieri A, Fervenza FC, Kumar S,

Lacy MQ, Lust JA, Greipp PR, Witzig TE, Hayman SR, Russell SJ, Kyle RA and Winters JL. Treatment of cast nephropathy with plasma exchange depends on the diagnosis and reduction of serum free light chains. Kidney Int. 2008; 73: 1282-1288.

101. Kaplan B, Ramirez-Alvarado M, Dispenzieri A, Zeldenrust SR, Leung N, Livneh A and

Gallo G. Isolation and biochemical characterization of plasma monoclonal free light chains in amyloidosis and multiple myeloma: a pilot study of intact and truncated forms of light chains and their charge properties. Clin Chem Lab Med. 2008; 46: 335-41.

102. Kumar S, Dispenzieri A, Lacy MQ, Hayman SR, Leung N, Zeldenrust SR, Buadi FD, Kyle

RA, Rajkumar SV and Gertz MA. Serum uric acid: Novel prognostic factor in primary systemic amyloidosis. Mayo Clin Proc. 2008; 83: 297-303.

103. Misra S, Gyamlani G, Sundararaman S, Buehrig CK, Bjarnason H, McKusick MA and

Leung N. The safety and effectiveness of transjugular renal biopsy in anticoagulated and coagulopathic patients. J Vasc Interv Radiol. 2008; 19: 546-51.

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104. Gertz M, Lacy M, Dispenzieri A, Hayman S, Kumar S, Buadi F, Leung N, Litzow M.

Troponin T level as an exclusion criterion for stem cell transplantation in light-chain amyloidosis. Leukemia & Lymphoma. 2008; 49: 36-41.

105. Fervenza FC, Cosio FG, Erickson SB, Specks U, Herzenberg AM, Dillon JJ, Leung N,

Cohen IM, Wochos DN, Bergstralh E, Hladunewich M, Cattran DC. Rituximab treatment of idiopathic membranous nephropathy. Kidney Int. 2008; 73: 117-125.

106. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Leung N, Gastineau DA.

Effect of hematologic response on outcome of patients undergoing transplantation for primary amyloidosis: importance of achieving a complete response. Haematologica. 2007; 92:1415-8.

107. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Leung N, Gastineau DA.

Transplantation without growth factor: engraftment kinetics after stem cell transplantation for primary systemic amyloidosis (AL). Bone Marrow Transplant. 2007; 40: 592-3.

108. Shanafelt TD, Lin T, Geyer SM, Zent CS, Leung N, Kabat B, Bowen D, Grever MR, Byrd

JC, Kay NE. Pentostatin, cyclophosphamide, and rituximab regimen in older patients with chronic lymphocytic leukemia. Cancer 2007; 109: 2291-98.

109. Leung N, Dispenzieri A, Lacy MQ, Kumar SK, Hayman SR, Fervenza FC, Cha SS, Gertz

MA. Severity of baseline proteinuria predicts renal response in immunoglobulin light chain-associated amyloidosis after autologous stem cell transplantation. Clin J Am Soc Neph 2007; 2: 440-4.

110. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar S, Leung N, Gastineau DA.

Impact of age and serum creatinine value on outcome after autologous stem cell transplant in patients with multiple myeloma. Bone Marrow Transplant. 2007; 39: 605-11.

111. Swaminathan S, Leung N, Lager DJ, Melton LJ III, Bergstralh EJ, Rohlinger A, and

Fervenza FC. Changing incidence of glomerular disease in Olmsted County, Minnesota: A 30-Year renal biopsy study. Clin J Am Soc Neph. 2006; 1: 483-7.

112. Leung N, Leung TR, Cha SS, Dispenzieri A, Lacy MQ, Gertz MA. Excessive Fluid

Accumulation during stem cell mobilization: A novel prognostic factor of first year survival after stem cell transplantation in AL amyloidosis patients. Blood. 2005; 106: 3353-7.

113. Gertz MA, Leung N, Lacy MQ, Dispenzieri A. Myeloablative chemotherapy and stem

cell transplantation in myeloma and primary amyloidosis with renal involvement. Kidney Int. 2005; 68: 1464-1471.

114. Leung N, Dispenzieri A, Fervenza FC, Lacy MQ, Villicana R, Cavalcante JL, Gertz MA.

Renal response after high dose melphalan and stem cell transplantation is a favorable marker in patients with primary systemic (AL) amyloidosis. Am J Kidney Dis. 2005: 46: 270-7.

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115. Leung N, Griffin MD, Dispenzieri A, Haugen EN, Gloor JM, Schwab TR, Textor SC, Lacy MQ, Litzow MR, Cosio FG, Larson TS, Gertz MA, Stegall MD. Living donor kidney and autologous stem cell transplantation for primary systemic amyloidosis (AL) with predominant renal involvement. Am J Transplant. 2005; 5: 1660-70.

116. Leung N, Slezak JM, Bergstralh EJ, Wolf RC, Lacy MQ, Dispenzieri A, Gertz MA. Acute

Renal Insufficiency Following High Dose Melphalan in Patients with Primary Systemic Amyloidosis During Stem Cell Transplantation. Am J Kidney Dis. 2005; 45: 102-111.

117. Leung N, Lager DJ, Gertz MA, Wilson K, Kanakiriya S, Fervenza FC. Long term outcome

of renal transplantation in light chain deposition disease. Am J Kidney Dis. 2004; 43: 147-53.

118. Cohen AJ, Stegall MD, Rosen CB, Wiesner RH, Leung N, Kremers WK and Zein NN.

Chronic renal dysfunction late after liver transplantation. Liver Transplant. 2002; 8: 916-921.

119. Leung N, Croatt AJ, Haggard JJ, Nath KA. Acute cholestatic liver disease protects

against glycerol-induced acute renal failure in the rat. Kidney Int. 2001; 60: 1047-57.

Case Reports:

1. Herrmann SM, Govani MV, Fidler ME, Nasr SH, Klink D, Amin C, Leung N, Fervenza FC.

Recurrence of monoclonal IgA lambda glomerulonephritis in kidney allograft associated with multiple myeloma. Clin Nephrol. 2015; 4: 241-6.

2. Cheungpasitporn W, Leung N, Rajkumar SV, Cornell LD, Sethi S,Angioi A, Fervenza FC Bortezomib-induced acute interstitial nephritis. Nephrol Dial Transplant. 2015; 30: 1225-9.

3. Cheungpasitporn W, Leung N. Sethi S, Gertz MA, Fervenza, FC. Refractory atypical

hemolytic uremic syndrome with monoclonal gammopathy responsive to bortezomib-based therapy. Clin Nephrol. 2015; 6: 363-9.

4. Leung N, Grogan M, Johnson GB, Klecka ME, Dispenzeiri A. Pulmonary masses in a patient with dyspnea: Apply Occam's razor or Hickam's dictum? Am J Hematol. 2015; 90: 462-5.

5. Gupta V, El Ters M, Kashani K, Leung N, Nasr SH. Crystalglobulin-Induced Nephropathy. J Am Soc Neph 2014;

6. Hamadah AM, Keddis MT, Cornell LD, Leung N. Proliferative Glomerulonephritis Due to Monoclonal Deposition With Organized Substructures. Am J Kidney Dis. 2014; 64: 994-8.

7. Patel K, Dillon JJ, Leung N, Bomback AS, Appel GB, D'Agati V, Canetta PA. Use of Bortezomib in Heavy-Chain Deposition Disease: A Report of 3 Cases. Am J Kidney Dis. 2014; 64: 123-7.

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8. Personett HA, Larson SL, Frazee EN, Nyberg SL, Leung N, El-Zoghby AM. Impact of Molecular Adsorbent Recirculating System Therapy on Tacrolimus Elimination: A Case Report. Transplant Proc. 2014; 46: 2440-2.

9. Leise MD, Leung N, El-Zoghby Z, Gonzalez, HCG, Cerhan JH, Nyberg SL. Treatment of Persistent/Medically Refractory Covert Hepatic Encephalopathy With the Molecular Adsorbent Recirculating System. Liver Transplant. 2014; 20: 867-8.

10. Keddis M, Leung N, Herrmann S, El-Zoghby Z, Sethi S. Adenovirus-Induced Interstitial Nephritis Following Umbilical Cord Blood Transplant for Chronic Lymphocytic Leukemia. Am J Kidney Dis. 2012; 886-90.

11. Orozco R, Fervenza FC, Contreras L, Leung N, Singh A, Fierro JA. Clinico-Pathological Conference on Acute Kidney Injury in a Patient with Nephrotic Syndrome. Nephron Clin Prac. 2011; 119: C240-C247.

12. Grafft C; Gunderson H; Langman, L; Farmer JC, Leung N. High-dose continuous

venovenous hemofiltration combined with charcoal hemoperfusion for methotrexate removal. Nephrol Dial Transplant Plus. 2011; 4: 87.

13. Tsapenko MV, Call TG, Lust JA, Leung N. Periodic fever syndrome with relapsing

glomerulonephritis: a case report and teaching points. Nephrol Dial Transplant PLUS. 2011; 4: 1340-3

14. Qian Q, Leung N, Theis JD, Dogan A, Sethi S. Coexistence of myeloma cast nephropathy,

light chain deposition disease, and nonamyloid fibrils in a patient with multiple myeloma. Am J Kidney Dis. 2010; 56: 971-6.

15. Sethi S, Fervenza FC, Miller D, Norby S, Leung N. Recurrence of Amyloidosis in a Kidney

Transplant. Am J Kidney Dis. 2010; 56: 394-8. 16. Lorenz EC, Sethi S, Poshusta TL, Ramirez-Alvarado M, Kumar S, Lager DJ, Fervenza FC,

Leung N. Renal failure due to combined cast nephropathy, amyloidosis and light chain deposition disease. Nephrol Dial Transplant. 2010; 4: 1340-3.

17. Leung N, Buadi FK, Song KW, Magil AB, Cornell LD. A case of bilateral renal arterial

thrombosis associated with cryocrystalglobulinaemia. NDT Plus. 2010; 3: 74 – 77. 18. Leung N, Eirin A, Irazabal MV, Maddox DE, Gunderson HD, Fervenza FC, Garovic VD.

Acute Kidney Injury in Patients with Inactive Cytochrome P450 Polymorphisms. Renal Failure. 2009; 31: 749-52.

19. Shaikh A, Wiisanen ME, Gunderson HD and Leung N. Acquired Fanconi Syndrome After

Treatment with Capecitabine, Irinotecan, and Bevacizumab. Ann Pharmacotherapy. 2009; 43: 1370-3.

20. Leung N, Pittelkow MR, Lee CU, Good JA, Hanley MM and Moyer TP. Chelation of

gadolinium with deferoxamine in a patient with nephrogenic systemic fibrosis. Nephrol Dial Transplant Plus. 2009; 2: 309-11.

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21. Leung N, Saucier NA, Zeldenrust SR, Gunderson HD, and Cornell LD. Acute renal failure after treatment with sunitinib in a patient with multiple myeloma. Nephrol Dial Transplant Plus. 2009; 2: 292-294.

22. Fervenza FC, Croatt AJ, Bittar CM, Rosehthal DW, Lager DJ, Leung N, Zeldenrust SR and

Nath KA. Induction of heme oxygenase-1 and ferritin in the kidney in warm antibody hemolytic anemia. Am J Kidney Dis. 2008; 52: 972-7.

23. Pillon L, Sweeting RS, Arora A, Notkin A, Ballard HS, Wieczorek RL and Leung N.

Approach to acute renal failure in biopsy proven myeloma cast nephropathy: Is there still a role for plasmapheresis? Kidney Int. 2008; 74: 956-61.

24. Shaikh, A, Habermann TM, Fidler ME, Kumar S and Leung N. Acute renal failure

secondary to severe type I cryoglobulinemia following Rituximab therapy for Waldenstrom’s macroglobulinemia. Clin Exp Nephrol. 2008; 12: 292-5.

25. Gera M, Griffin MD, Specks U, Leung N, Stegall MD, Fervenza FC. Recurrence of

ANCA-associated vasculitis following renal transplantation in the modern era of immunosuppression. Kidney Int. 2007; 71: 1296-301.

26. Hoyer RJ, Leung N, Witzig TE, Lacy MQ. Treatment of diuretic refractory pleural

effusions with bevacizumab in four patients with primary systemic amyloidosis. Am J Hem. 2007; 82: 409-13.

27. Soares SM, Lager DJ, Leung N, Haugen EN, Fervenza FC. A proliferative

glomerulonephritis secondary to a monoclonal IgA. Am J Kidney Dis. 2006; 47: 342-9. 28. Pena de la Vega, L, Lager DJ, Habermann TM, Leung N. Acute granulomatous interstitial

nephritis secondary to bisphosphonate alendronate sodium. Renal Failure. 2005; 27: 485-9. 29. Borza DB, Chedid MF, Colon S, Lager DJ, Leung N, Fervenza FC. Goodpasture's disease

secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha1/alpha2 chains of type IV collagen. Am J Kidney Dis. 2005; 45: 397-406.

30. Rosenthal D, Lien YH, Lager D, Lai LW, Shang S, Leung N, Fervenza FC. A novel alpha-

galactosidase a mutant (M42L) identified in a renal variant of Fabry disease. Am J Kidney Dis. 2004; 44(5):e85-9.

31. Leung N, Ytterberg SR, Blute ML, Lager DJ, Fervenza FC. Wegener granulomatosis

presenting as multiple bilateral renal masses. Nephrol Dial Transplant. 2004; 19: 984-7.

32. Leung N, O’Brien T, McMahon MM. Parenteral feeding in a patient with hypertriglyceridemia and increased liver enzyme level. Endo Prac. 1999; 5: 194-8.

Invited Articles:

1. Leung N and Nasr SH. Myeloma-related Kidney Disease. Adv Chronic Kidney Dis. 2014; 21: 36-47.

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2. Leung N. Hematologic manifestations of kidney disease. Semin Hematol. 2013; 50: 207-

215.

3. Leung N and Behrens J. Current Approach to Diagnosis and Management of Acute Renal Failure in Myeloma Patients. Adv Chronic Kidney Dis. 2012; 19: 297-302.

4. Haynes R, Leung N, Kyle, R, Winearls CG. Myeloma Kidney: Improving Clinical Outcomes? Adv Chronic Kidney Dis. 2012; 19: 342-51.

5. Leung N and Rajkumar SV. Renal manifestations of plasma cell disorders. Core Curriculum. AJKD. 2007; 50: 155-65.

Editorials:

1. Leung N. To biopsy or not to biopsy, that is the question in myeloma cast nephropathy. Nephrol Dial Transplant. 2016; 1: 1-3.

2. Leung N and Witzig TE. The use of (90)yttrium-ibritumomab tiuxetan in patients on dialysis: what do we know regarding its pharmacokinetics? Leukemia & Lymphoma 2013; 54: 2586-7.

3. Leung N and Gertz MA. The spectrum of monoclonal gammopathies affecting the kidney. Leukemia & Lymphoma. 2012; 53: 1656-7.

4. Leung N. Treating myeloma cast nephropathy without treating myeloma. J Clin Invest. 2012; 5: 1605-8.

5. Williamson EE, Knudsen J, Leung N. Gadolinium and Nephrogenic Systemic Fibrosis:

Practice Management in a Time of Uncertainty. Nephrology Self Assessment Program. 2008; 7: 213-7.

6. Rule AD and Leung N. Eprodisate slows the progression of renal disease in patients with

AA amyloidosis. Nat Clin Pract Nephrol. 2007; 3: 592-3.

7. Swaminathan S and Leung N. Nephrogenic Fibrosing Dermopathy: lessons from the past. Int J Dermatol. 2006; 45: 639-41.

8. Leung N and Textor SC. Acute renal failure after liver transplantation: The role of

dopamine and fenoldopam. Liver Transplant. 2004; 10: 993-4.

9. Leung N. A tale of two markers. Liver Transplant. 2002;8:600-2 Published Letters and correspondence:

1. Burnette BL, Leung N, Rajkumar SV. Renal Improvement in Myeloma with Bortezomib plus Plasma Exchange. New Engl J Med. 2011; 364: 2365-6.

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2. Leung N, Gloor JM, Dean PG, Lacy MQ, Porrata LF, Griffin MD. Acute cellular rejection in a renal allograft immediately following leukocyte engraftment after auto-SCT. Bone Marrow Transplantation. 2009; 43: 345-6.

3. Leung N. Making the diagnosis of immunotactoid glomerulonephritis. Ann Hematol.

2009; 88: 95-6.

4. Swaminathan S, Ahmed I, McCarthy JT, Albright RC, Pittelkow MR, Caplice NM, Griffin MD, Leung N. Nephrogenic Fibrosing Dermopathy and High Dose Erythropoietin Therapy. Ann Intern Med. 2006; 145 (3): 234.

5. Leung N. Plasma exchange in multiple myeloma. Ann Intern Med. 2006; 144(6): 455.

Book Chapters:

1. Leung N, Textor SC. Vascular injury to the kidney. In: Kasper DL; et al editor. Harrison's principles of internal medicine. 19th Edition. Volume II. New York: McGraw Hill Education; 2015. p. 1863-6.

2. Leung N. Amyloidosis. In: Fervenza FC; et al. Core concepts in parenchymal kidney disease. New York: Springer; 2014. p. 301-14.

3. Kattah AG, Leung N. Monoclonal immunoglobulin deposition disease. In: Fervenza FC; et

al editor. Core concepts in parenchymal kidney disease. New York: Springer; 2014. p. 291-300.

4. Textor SC and Leung N. Vascular injury to the kidney. In: Longo DL; et al editor. Harrison's

principles of internal medicine. 18th Edition. New York: McGraw-Hill Medical; 2012, p. 2375-82.

5. Lacy MQ and Leung N. Supportive Care for Amyloidosis. Amyloidosis: Diagnosis and

Treatment 1st Edition. Eds Gertz MA and Rajkumar SV, New York, Springer, 2010, 65-76. 6. Zeldenrust SR, Lager DJ, Leung N. Light Chain Deposition Disease. Multiple Myeloma and

Related Plasma Cell Disorders. Eds. Gertz MA and Greipp PR. Berlin, Springer-Verlag, 2003, 197-203.

7. Leung N, Ghosh AK, Nath KA. Approach to Patient with Urinary Retention and

Obstruction. Kelley’s Textbook of Internal Medicine 4th Edition. Ed. Humes HD, Philadelphia, Lippincott Williams & Wilkins, 1112-9.

8. Leung N, Ghosh AK, Nath KA. Obstructive Uropathy. Kelley’s Textbook of Internal

Medicine 4th Edition. Ed. Humes HD, Philadelphia, Lippincott Williams & Wilkins, 1238-43.

Abstracts:

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1. Yui J, Abraham RS, Chen D, Fervenza F, Go RS, Sethi, Tran C, Winters JL, Amer H, Ashrani AA, Cramer II C, Elliott MA, Garovic V, Hogan WJ, Hook CC, Lorenz E, Murray DL, Botero JP, Pruthi RK, White W, Willrich MAV, Leung N. Novel Genetic Variants in Complement-Mediated Thrombotic Microangiopathy. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

2. Milani P, Dispenzieri A, Gertz MA, Lacy MQ, Baudi FK,2 Kumar SK,. Maurer MS, Klarich K, Hayman SR, Leung N, Dingli D, Lust JA, Lin Y, Kapoor P, Go RS, Hwa YL, Zeldenrust SR, Kyle RA, Rajkumar SV, Grogan M. In Patients with Light-Chain (AL) Amyloidosis Myocardial Contraction Fraction (MCF) Is a Simple, but Powerful Prognostic Measure That Can be Calculated from a Standard Echocardiogram (ECHO). (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

3. Milani P, Gertz MA, Merlini G, Palladini G, Lacy MQ, Baudi FK, Kumar SK, Hayman SR,

Leung N, Dingli D, Lust JA, Lin Y, Kapoor P, Go RS, Zeldenrust SR, Hwa YL, Kyle RA, Rajkumar SV, Dispenzieri A. N-Terminal Fragment of the Type-B Natriuretic Peptide (NT-proBNP) Is a Prognostic Factor for Overall Survival in Newly Diagnosed Patients with Multiple Myeloma (MM). (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

4. Kourelis T, Buadi F, Gertz MA, Kumar S, Lacy MQ, Kapoor P, Go RS, Lust JA, Hayman

SR, Rajkumar SV, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Leung N, Kyle RA, Gonsalves WI, DispenzieriA. Presentation and Outcomes of Localized Amyloidosis: The Mayo Clinic Experience. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

5. Warsame R, Kumar S, Thompson CA, Gertz MA, Lacy MQ, Buadi F, Hayman SR, Leung N,

Dingli D, Hwa YL, Lust JA, Kapoor P, Lin Y, Go RS, Zeldenrust SR, Kyle RA, Rajkumar SV, Dispenzieri A. AL Amyloidosis and Patient Reported Quality of Life. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

6. Binder M, Rajkumar SV, Ketterling RP, Dispenzieri A, Lacy MQ, Gertz MA, Buadi F,

Hayman SR, Hwa YL, Zeldenrust SR, Lust JA, Russell SJ, Leung N, Kapoor P, Go RS, Gonsalves WI, Kyle RA, Kumar SK. Occurrence and Prognostic Significance of Cytogenetic Evolution in Patients with Multiple Myeloma. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

7. Hwa YL, Kumar SK, Lacy MQ, Gertz MA, Buadi F, Rajkumar SV, Go RS, Leung N,

Kapoor P, Dingli D, Russell SJ, Lust JA, Hayman SR, Kourelis T, Dispenzieri A. Impact of Bone Marrow Plasmacytosis on Outcome in Patients with AL Amyloidosis Following Autologous Stem Cell Transplant. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

8. Chakraborty R, Kumar S, Buadi F, Dingli D, Dispenzieri A, Hayman SR, Hogan WJ, Kapoor

P, Lacy MQ, Leung N, Gertz MA. The Impact of Induction Regimen Choice on Transplant Outcome and Survival in Newly Diagnosed Multiple Myeloma in the Era of Novel Agents. (Poster) 57TH ASH Annual Meeting and Exposition, Orlando, FL, December 5-8, 2015.

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9. Jaffer Sathick I, Klobucher TV, Leung N, Nasr SH. Cryoglobulinemic Glomerulonephritis: A Single-Center Experience. (Poster) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

10. Hamadah AM, Gharaibeh KA, Nasr SH, Leung N. Glucosuria in Normoglycemic Non-

Diabetic Kidney Disease: Not Necessarily due to an Isolated Proximal Tubule Defect. (Poster) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

11. Jaffer Sathick I, Zand L, Nasr SH, Sethi S, Fervenza FC, Leung N. Steroids Alone for the Treatment of C3 Glomerulonephritis with Monoclonal Gammopathy. (Poster) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

12. Jaffer Sathick I, Nasr SH, Leung N. Cast Nephropathy versus Acute Tubular Necrosis in Newly Diagnosed Multiple Myeloma: A Comparative Study. (Poster) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

13. Kittanamongkolchai W, El-Zoghby Z, Leung N. Charcoal Hemoperfusion in the Treatment of

Pruritus in Cholestatic Liver Disease. (Poster) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

14. Gharaibeh KA, Hamadah AM, Leung N, El-Zoghby Z. Incidence and Predictors of Acute

Kidney Injury After Total Hip Replacement. (Plenary) American Society of Nephrology Kidney Week, San Diego, CA, Nov 3-8, 2015.

15. Lacy MQ, LaPlant BR, Laumann KM, Kumar S, Gertz MA, Hayman SR, Buadi F,

Dispenzieri A, Lust JA, Kapoor P, Leung N, Russell S,Dingli D, Go RS, Gonsalves WI, Fonseca R, Bergsagel L, Roy V, Sher T, Ailawadhi S, Chanan-Khan A, Stewart AK, Reeder CB, Rajkumar SV, Mikhael JR. Pomalidomide Plus Low-Dose Dexamethasone (Pom/Dex) in Relapsed Lenalidomide Refractory Myeloma: Long Term Follow up and Comparison of 2 Mg Vs 4 Mg Doses. (Plenary) 56th ASH Annual Meeting and Exposition, San Francisco, CA December 6-9, 2014.

16. Gonsalves WI, Leung N, Rajkumar SV, Dispenzieri A, Buadi F, Lacy MQ, Dingli D, Kapoor P, Go RS, Lust JA, Hayman SR, Lin Y, Zeldenrust SR, Kyle RA, Gertz MA, Kumar S. Improvement in Renal Function and Its Impact on Survival in Patients with Newly Diagnosed Multiple Myeloma. (Poster) 56th ASH Annual Meeting and Exposition, San Francisco, CA, December 6-9, 2014.

17. Lacy MQ, LaPlant BR, Laumann KM, Kumar S, Gertz MA, Hayman SR, Buadi F,

Dispenzieri A, Lust JA, Kapoor P, Leung N, Russell SJ, Dingli D, Gonsalves WI, Fonseca R, Bergsagel L, Roy V, Sher T, Ailawadhi S, Chanan-Khan A, Stewart AK, Reeder CB, Rajkumar SV, Mikhael JR. Pomalidomide, Bortezomib and Dexamethasone (PVD) for Patients with Relapsed Lenalidomide Refractory Multiple Myeloma (MM). (Plenary) 56th ASH Annual Meeting and Exposition, San Francisco, CA, December 6-9, 2014.

18. Paludo J, Vallumsetla N, Kumar S, Ketterling R, Gertz MA, Dispenzieri A, Lacy MQ, Buadi

FK, Dingli D, Painuly U, Leung N, Kyle R, Rajkumar SV, Kapoor P. Impact of Novel Agents on Young Patients with t(11;14) Multiple Myeloma. (Plenary) 56th ASH Annual Meeting and Exposition, San Francisco, CA, December 6-9, 2014.

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19. Hamadah AM, Finnes HD, Thompson C, Leung N. Safety, Efficacy, and Dose Adjustment of Chemotherapy in Lymphoma Patients Requiring Hemodialysis - A Case Series. (Poster) American Society of Nephrology Kidney Week, Philadelphia PA, November 11 - 16, 2014.

20. Jaffer Sathick I, Kattah AG, Leung N. Xanthine Nephropathy, a Rare Manifestation of Tumor Lysis Syndrome. (Poster) American Society of Nephrology Kidney Week, Philadelphia PA, November 11 - 16, 2014.

21. Bhutani G, Sethi S, Nasr SH, Fervenza FC, Leung N. Progression of Renal Disease and Treatment Outcomes in Proliferative Glomerulonephritis Associated with Non-Organized Monoclonal Immunoglobulin Deposits. (Poster) American Society of Nephrology Kidney Week, Philadelphia PA, November 11 - 16, 2014.

22. Safadi S, Saad A, Leung N, Kurtin PJ, Nasr SH. Regression of Immunoglobulin (IG) Deposits in Renal Amyloidosis after Successful Autologous Stem Cell Transplant (ASCT). (Poster) American Society of Nephrology Kidney Week, Philadelphia PA, November 11 - 16, 2014.

23. Safadi S, Leung N, Cosio F, Amer H, Gertz M, Rajkumar V, Hayman S, Lacy M, Dispenzieri A. De novo multiple myeloma after kidney transplantation. (Poster) National Kidney Foundation 2014 Spring Clinical Meetings. Las Vegas, NV. April 22 – 6, 2014.

24. Sathick IJ, Fidler ME, Lacy MQ, Leung N. Recurrent light chain proximal tubulopathy after renal and autologous stem cell transplantation. (Poster) National Kidney Foundation 2014 Spring Clinical Meetings. Las Vegas, NV. April 22 – 6, 2014.

25. Kourelis T, Kumar SK, Srivastava G, Gertz MA, Lacy MQ Buadi FK, Hayman SR, Zeldenrust SR, Leung N, Kyle R, Russell S, Dingli D, Lust JA, Lin Y, Kapoor P, McCurdy A, Rajkumar V, Dispenzieri A. Long Term Response To Lenalidomide With and Without Continuous Therapy Among Patients With Newly Diagnosed Multiple Myeloma. (Poster) 55th ASH Annual Meeting and Exposition, New Orleans, LA, December 7-10, 2013.

26. Bhutani G, Fervenza FC, Sethi S, Nasr SH, Leung N. The Prevalence of Circulating

Monoclonal Protein in Proliferative Nephropathy with Monoclonal Deposits. (Plenary) American Society of Nephrology Kidney Week 2013, Atlanta, GA, November 7 - 10, 2013.

27. Nasr SH, Shanafelt T, Hanson C, Sethi S, Cornell LD, Fidler ME, Leung N. Granulomatous Interstitial Nephritis Secondary to Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. (Poster) American Society of Nephrology Kidney Week 2013, Atlanta, GA November 7 - 10, 2013.

28. Burnette BL, Gertz M, Kumar S, Lacy M, Buadi F, Hayman S, Dingli D, Inwards DJ,

Johnston PB, Micallef IN, Porrata LE, Hogan W, Litzow MR, Patnaik M, Hashmi S, Leung N, Afessa B, Gastineau D, Ansell SM, Holtan S, Dispenzieri A. Redefining engraftment syndrome: the new Mayo Clinic criteria. (Poster) 2013 BMT Tandem Meetings, Salt Lake City, UT. February 13-7, 2013.

29. Raval, GG, Gertz MA, Lacy MQ, Hayman SR, Kumar SK, Buadi FK, Lust JA, Zeldenrust SR, Dingli D, Hall RL, Hwa L, Lin Y, Kapoor P, Witzig TE, Kyle RA, Russell S, Leung N, Rajkumar SV, Dispenzieri A. Survival After Second, Third, and Fourth Line Therapy Better

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Than Expected in Patients with Previously Treated AL Amyloidosis Who Were Not Transplant Candidates At Diagnosis. (Plenary) 54rd ASH Annual Meeting and Exposition, Atlanta, GA December 8-11, 2012.

30. Warsame R, Bang SM, Kumar SK, Lacy MQ, Buadi FK, Dingli D, Hayman DR, Lust JA, Russell S, Witzig TE, Kyle RA, Leung N, Zeldenrust SR, Rajkumar SV Gertz MA, Dispenzieri A. Outcomes and Treatments of Relapsed AL Amyloidosis Following Stem Cell Transplant. (Poster) 54rd ASH Annual Meeting and Exposition, Atlanta, GA December 8-11, 2012.

31. Nasr SH, Said SM, Valeri AM, Sethi S, Cornell LD, Fidler ME, Gertz MA, Dispenzieri A,

Buadi FK, Vrana JA, Theis JD, Dogan A, Leung N. Renal Heavy Chain and Heavy+Light Chain Amyloidosis: A Report of 17 Cases and Comparison with Renal Light Chain Amyloidosis. (Poster) 54rd ASH Annual Meeting and Exposition, Atlanta, GA December 8-11, 2012.

32. Gertz MA, Lacy MQ, Dispenzieri A, Kumar SK, Dingli D, Leung N, Hogan WJ, Buadi FK,

Hayman SR. Refinement in Patient Selection to Reduce Treatment-Related Mortality From Stem Cell Transplantation in Amyloidosis. (Plenary) 54rd ASH Annual Meeting and Exposition, Atlanta, GA December 8-11, 2012.

33. Humeniuk M, Gertz MA, Lacy MQ, Kyle RA, Hayman SR, Kumar SK, Lust JA, Witzig TE,

Buadi FK, Rajkumar SV, Zeldenrust SR, Russell SJ, Dingli D, Lin Y, Kapoor P, Leung N, Dispenzieri A. Outcomes of Patients with POEMS Syndrome Treated Initially with Radiation. (Plenary) 54rd ASH Annual Meeting and Exposition, Atlanta, GA December 8-11, 2012.

34. Sethi S, Vrana JA, Theis JD, Sethi A, Nasr SH, Cornell LD, Leung N, Fervenza FC. Laser

Microdissection and Proteomic Analysis of Amyloidosis, Fibrillary and Immunotactoid Glomerulonephritis. (Poster) American Society of Nephrology Kidney Week 2012, San Diego, CA, October 20 – November 4, 2012.

35. Zand L, Nasr SH, Leung N. Renal and Survival Outcome of Patients with Combined Renal

Light Chain Deposition Disease (LCDD) & Myeloma Cast Nephropathy (MCN). (Poster) American Society of Nephrology Kidney Week 2012, San Diego, CA, October 20 – November 4, 2012.

36. Muriithi AK, Nasr SH, Leung N. Do Urine Eosinophils Have a Role in the Diagnosis of

Acute Interstitial Nephritis? (Poster) American Society of Nephrology Kidney Week 2012, San Diego, CA, October 20 – November 4, 2012.

37. Muriithi AK, Leung N, Cornell LD, Fidler ME, Sethi S, Nasr SH. Acute Interstitial Nephritis: A Current Perspective. (Poster) American Society of Nephrology Kidney Week 2012, San Diego, CA, October 20 – November 4, 2012.

38. Patel K, Dillon JJ, Leung N, Bomback AS, Appel GB, Canetta PA. Bortezomib for Heavy

Chain Deposition Disease: A Report of Three Cases. (Poster) American Society of Nephrology Kidney Week 2012, San Diego, CA, October 20 – November 4, 2012.

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39. Lorenz EC, Dierkhising RA, Sethi S, Leung N, Fervenza FC, Amer A, Cosio FG. Heterogeneity of Membranoproliferative Glomerulonephritis (MPGN) Following Kidney Transplantation (KTx). (Poster) American Transplant Congress. Boston, MA, Jun 2 -6, 2012.

40. Asrani SK, Allen A, Leung N, El-Zoghby Z, Rule AD, Fan C, Therneau TM, Kim WR.

Incorporation of Cystatin-C in Estimating Glomerular Filtration Rate in Liver Transplant Recipients. (Poster) American Transplant Congress. Boston, MA, Jun 2 -6, 2012.

41. Dispenzieri A, Gertz MA, Saenger AK, Grogan M, Kumar S, Lacy MQ, Kyle RA, Leung N,

Zeldenrust S, Hayman SR, Buadi FK, Greipp PR, Rajkumar SV, Russell S, Dingli D, Lust JA, Jaffe A. The Utility of High Sensitivity Cardiac Troponin Among Patients with Immunoglobulin Light Chain Amyloidosis. (Poster) 53rd ASH Annual Meeting and Exposition, San Diego CA, December 10-13, 2011.

42. Glavey SV, Dispenzieri A, Gertz MA, Kumar S, Lacy MQ, Buadi FK, Rajkumar SV,

Hayman SR, Lust JA, Russell SJ. Zeldenrust SR, Dingli D, Hall RL, Leung N. The Depth of Renal Response Strongly Predicts Overall Survival in Patients with AL Amyloidosis. (Poster) 53rd ASH Annual Meeting and Exposition, San Diego CA, December 10-13, 2011.

43. Leung N, Kumar S, Dispenzieri A, Lacy MQ, Buadi FK, Hayman SR, Dingli D, Hogan WJ.

Gastineau DA, Glavey SV, Gertz MA. The Timing of Acute Renal Failure Strongly Affects Survival of Immunoglobulin Light Chain (AL) Amyloidosis Patients Undergoing Autologous Stem Cell Transplantation. (Poster) 53rd ASH Annual Meeting and Exposition, San Diego CA, December 10-13, 2011.

44. Leung N, Bridoux F, Kumar S, Cook M Rajkumar SV, Ecotiere L, Ludwig H, Hutchison CA.

Both Hematologic and Renal Response Affect Overall Survival of Myeloma Patients with Acute Kidney Injury. (Poster) 53rd ASH Annual Meeting and Exposition, San Diego CA, December 10-13, 2011.

45. Glavey SV, Leung N. Long Term Renal Outcomes Following Autologous Stem Cell

Transplant for Multiple Myeloma. (Poster) American Society of Nephrology 2011 Annual Meeting, Philadelphia PA 2011.

46. Said SM, Leung N, Herrmann S, Sethi S, Cornell LD, Fidler ME, Grande JP, D'Agati VD,

Nasr SH. Myeloproliferative Neoplasm-Related Glomerulopathy. (Poster) American Society of Nephrology 2011 Annual Meeting, Philadelphia PA 2011.

47. Nasr SH, Valeri AM, Sethi S, Fidler ME, Cornell LD, Leung N. Clinical Pathologic

Correlations in 190 Multiple Myeloma Patients with Kidney Biopsy. (Plenary) American Society of Nephrology 2011 Annual Meeting, Philadelphia PA 2011.

48. Herrmann S, Nasr SH, Said SM, Leung N. Renal Involvement in Patients with Primary

Myelofibrosis: Fact or Fiction? (Poster) American Society of Nephrology 2011 Annual Meeting, Philadelphia PA 2011.

49. Nasr SH, Valeri AM, Cornell LD, Fidler ME, Sethi S, Leung N. Renal Monoclonal

Immunoglobulin Deposition Disease: A Report of 64 Cases from a Single institution. (Poster) American Society of Nephrology 2011 Annual Meeting, Philadelphia PA 2011.

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50. Kumar S, Gertz M, Lacy M, Dingli D, Hayman SR, Buadi F, Detweiler-Short K, Zeldenrust S, Leung N, Greipp PR, Lust J,Russell S, Kyle R, Rajkumar V, Dispenzieri A. Recent Improvements In Survival In Light Chain Amyloidosis and the Importance of An Early Mortality Risk Score. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

51. Irazabal MV, Eirin A, Gertz MA, Dispenzieri A, Kumar S, Buadi F, Lacy M, Hayman SR,

Dingli D, Hogan WJ, Leung N. Acute Renal Failure Is a Common Presentation of Engraftment Syndrome In Light Chain Amyloidosis (AL) Patients After Autologous Stem Cell transplantation. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

52. Gertz MA, Gastineau D, Lacy M, Dispenzieri A, Hayman SR, Kumar S, Dingli D, Leung N,

Wolf R, Hogan WJ, Buadi F. Stem Cell Transplant without Growth Factor In Multiple Myeloma: Engraftment Kinetics, Bacteremia, and Hospitalization. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

53. Gertz MA, Lacy M, Dispenzieri A, Kumar S, Buadi F, Dingli D, Leung N, Hogan WJ,

Hayman SR. Trend towards Improved Day 100 and 2-Year Survival After SCT for AL Amyloidosis: Outcomes Before and After 2006. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

54. Gertz MA, Lacy M, Dispenzieri A, Kumar S, Buadi F, Dingli D, Ansell SM, Gastineau D,

Inwards DJ, Johnston PB, Litzow MR, Micallef I, Porrata L, Leung N, Wolf R, Hogan WJ, Hayman SR. Transplantation for Immunoglobulin Light Chain Amyloidosis. A Statistical Analysis of Factors Predicitng Outcome In Over 400 Patients. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

55. Eirin A, Irazabal MV, Gunderson HD, Leung N. Evaluation of Low Dose Rasburicase In the

Prevention of Renal Insufficiency and Dialysis After Chemotherapy. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

56. Leung N, Kumar S, Dispenzieri A, Lacy M, Buadi F, Dingli D, Hogan WJ, Gastineau D,

Gertz MA. Comparison of Troponin T and N-Terminal-Pro-Brain Natriuretic Peptides In Two Models of Treatment Related Mortality In AL Amyloidosis Patients Following Autologous Stem Cell Transplantation. (Poster) 52nd ASH Annual Meeting and Exposition, Orlando FL, December 4-7, 2010.

57. Dogan A, Theis JD, Gamez JD, Grogg KL, Leung N, Dispenzieri A, Zeldenrust SR, Vrana

JA. Proteome of serum amyloid A protein (SAA) associated amyloidosis (AA). (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

58. Ramirez-Alvarado M, Ward CJ, Huang BQ, Gong X, Hogan MC, Madden BJ, Charlesworth

C, Leung N. Oligomeric amyloidogenic light chains are found in urinary exosomes of patients with AL amyloidosis. (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

59. Leung N, Kumar S, Dispenzieri A, Lacy MQ, Buadi F, Hayman SR, Dingli D, Hogan WJ,

Gertz MA. A model using cardiac troponin T, albumin and uric acid accurately predicts treatment related mortality in patients with amyloidosis undergoing autologous stem cell

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transplantation. (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

60. Dogan A, Theis JD, Vrana JA, Jimenez-Zepeda VH, Lacy MQ, Leung N, Dispenzieri A,

Zeldenrust SR, Fonseca R, Gilbertson JA, Hunt T, Wechalekar AD, Lachmann HJ, Rowczenio D, Hawkins PN, Gillmore JD. Clinical and pathological phenotype of leukocyte cell-derived chemotaxin-2 (LECT2) amyloidosis (ALECT2). (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

61. Dispenzieri A, Gertz MA, Saenger AK, Kumar SK, Lacy MQ, Kyle RA, Leung N,

Zeldenrust SR, Hayman SR, Buadi F, Greipp PR, Rajkumar SV, Russell SR, Detweiler-Short D, Dingli D, Lust JA, Jaffe AS. High sensitivity troponin assay (hsTnT): utility in patients with AL. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

62. Gertz MA, Lacy MQ, Dispenzieri A, Kumar S, Hayman SR, Buadi F, Dingli D, Leung N,

Hogan WJ. Trend toward improved day 100 and 2 year survival following stem cell transplantation for AL. A comparison before and after 2006. (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

63. Kumar S, Dispenzieri A, Lacy M, Hayman S, Buadi F, Short-Detweiler K, Zeldenrust SR,

Leung N, Dingli D, Greipp P, Lust J, Russell S, Kyle R, Rajkumar V, Gertz M. Improved survival in light chain amyloidosis. (Plenary) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

64. Leung N, Herrmann SMS, Dispenzieri A, Kumar S, Lacy MQ, Russell SJ, Buadi FK,

Hayman SR, Zeldenrust SR, Dingli D, Dean PG, Prieto M, Nyberg S, Stegall M, Fervenza FC, Gertz MA. Long-term outcome after kidney transplantation with or without stem cell transplantation in immunoglobulin light chain (AL) amyloidosis. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

65. Leung N, Gertz MA, Dispenzieri A, Lacy MQ, Buadi F, Hayman SR, Dingli D, Hogan WJ,

Irazabal MV, Eirin A, Kumar S. Engraftment syndrome presenting as acute renal failure in light chain amyloidosis patients after autologous stem cell transplantation. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

66. Leung N, Irazabal MV, Eirin A, Lacy MQ, Dispenzieri A, Buadi FK, Zeldenrust SR,

Hayman SR, Kumar S, Russell SJ, Kyle RA, Ramirez-Alvarado M, Sethi S, Erickson SB, Fervenza FC, Gertz MA. Differences in clinical presentation and outcomes of patients with vascular limited light chain amyloidosis (AL) versus diffuse. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

67. Dispenzieri A, Kumar SK, Lacy MQ, Kyle RA, Leung N, Zeldenrust SR, Hayman SR, Buadi

F, Greipp PR, Russell SR, Detweiler-Short K, Dingli D, Lust JA, Rajkumar SV, Gertz MA. Do the immune modulatory drugs (IMiDs1) affect levels of troponin T (TnT) and N-terminal brain natriuretic peptide (NTproBNP) in patients with immunoglobulin light chain amyloidosis (AL)? (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

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68. Kumar S, Dispenzieri A, Clark R, Larson D, Colby C, Zeldenrust S, Lacy M, Hayman S, Buadi F, Leung N, Ramirez-Alvarado M, Kyle RA, Katzmann JA, Rajkumar SV, Gertz MA. Serum immunoglobulin free light chain in AL amyloidosis: prognostic value and correlations with clinical features. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

69. Kumar S, Gertz M, Lacy M, Hayman S, Buadi F, Zeldenrust S, Ramirez-Alvarado M, Leung

N, Dispenzieri A. Changes in serum free light chain rather than intact monoclonal immunoglobulin levels predict outcome with therapy in patients with light chain amyloidosis. (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

70. Kumar S, Dispenzieri A, Lacy M, Hayman S, Buadi F, Zeldenrust S, Leung N, Ramirez-

Alvarado M, Kyle RA, Rajkumar SV, Gertz MA. A novel prognostic staging system for light chain amyloidosis (AL). (Poster) XII International Symposium on Amyloidosis, St. Peter’s Rome, April 18–21, 2010.

71. Kumar S, Dispenzieri A, Lacy MQ, Hayman S, Buadi F, Zeldenrust SR, Leung N, Ramirez-

Alvarado M, Kyle RA, Rajkumar SV, Gertz MA. A Novel Prognostic Staging System for Light Chain Amyloidosis (AL) Incorporating Markers of Plasma Cell Burden and Organ Involvement. (Plenary) American Society of Hematology 2009 Annual Meeting, New Orleans, LA, 2009.

72. Kumar S, Gertz MA, Lacy MQ, Hayman SR, Buadi F, Zeldenrust SR, Ramirez-Alvarado M,

Leung N, Dispenzieri A. Changes in Serum Free Light Chain Rather Than Intact Monoclonal Immunoglobulin Levels Predict Outcome with Therapy in Patients with Light Chain Amyloidosis. (Plenary) American Society of Hematology 2009 Annual Meeting, New Orleans, LA, 2009.

73. Christensen K, Lee C, Hanley M, Leung N, Moyer T, Pittelkow M. Quantification of

Gadolinium in Fresh Skin and Serum Samples from Patients with Nephrogenic Systemic Fibrosis. (Plenary) RSNA 2009 95th Scientific Assembly and Annual Meeting, Chicago, IL 2009.

74. Herrmann SM, Gertz MA, Stegall MD, Dispenzieri A, Kumar S, Lacy MQ, Dean PG, Prieto

M, Nyberg SL, Fervenza FC, Leung N. Long-Term Outcome after Renal Transplantation with or without Stem Cell Transplantation for Immunoglobulin Light Chain (AL) Amyloidosis. (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

75. Craici I, Wagner S, Juskewitch J, Heimbach J, Rosen C, Leung N. Predictors of Renal

Recovery after Liver Transplantation (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

76. Eirin A, Irazabal MV, Abraham RS, Erickson SB, Nachman PH, Lieske JC, Leung N, Dillon

JJ, Cattran DC, Fervenza FC. Quantification of B Cell and T Cell Subsets Do Not Predict Response to Rituximab Therapy in Patients with Idiopathic Membranous Nephropathy: A Prospective Study. (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

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77. Fervenza FC, Erickson SB, Nachman PH, Dillon JJ, Leung N, Hogan MC, Hickson LT, Qazi Q, Bergstralh EJ, Irazabal MV, Erin A, Cattran DC. Rituximab (RTX) in the Treatment of Idiopathic Membranous Nephropathy (IMN). (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

78. Irazabal MV, Eirin A, Erickson SB, Leung N, Dillon JJ, Keryakos H, Cattran DC, Fervenza

FC. Long-Term Outcome of Patients with Membranous Nephropathy after Rituximab Therapy. (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

79. Fervenza FC, Erickson SB, Nachman PH, Dillon JJ, Leung N, Hogan MC,. Hickson LT,

Anand B, Visich J, Irazabal MV, Eirin A, Cattran DC. Pharmacokinetics (PK) of Rituximab in Idiopathic Membranous Nephropathy (IMN). (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

80. Leung N, Irazabal MV, Eirin A, Gunderson HD, Fervenza FC. Efficacy of Rasburicase in

the Prevention of Acute Kidney Injury of Tumor Lysis Syndrome. (Poster) American Society of Nephrology 2009 Annual Meeting, San Diego, CA 2009.

81. Christensen KN, Lee CU, Hanley MM, Leung N, Moyer TP, Pittelkow MR. Comparison of

gadolinium concentrations in fresh skin and blood samples from patients with normal renal function after contrast-enhanced MRI and from patients on hemodialysis. (Plenary) Contrast Media Research - CMR 2009, Copenhagen, Denmark, 2009.

82. Leung N, Gunderson HD, Tan TS, Dispenzieri A, Gertz MA, Zeldenrust SR, Lacy MQ,

Buadi FK, Hayman SR, Kumar S. Melphalan and Dexamethasone is less effective for patients with immunoglobulin light chain amyloidosis (AL) with >20% bone marrow plasma cells. (Poster) American Society of Hematology 2008 Annual Meeting, San Francisco CA, 2008.

83. Fervenza FC, Erickson SB, Dillon JJ, Nachman P, Hogan MC, Haugen EN, Leung N,

Wochos DN, Cattran DC. Angiotensin II (Ang II) Blockade Is Ineffective in Reducing Proteinuria in Patients with Severe Membranous Nephropathy (MN). (Poster) American Society of Nephrology 2008 Annual Meeting, Philadelphia, PA 2008.

84. Silva F, Specks U, Leung N, Kalra S, Fervenza FC. A Pilot Study of Mycophenolate Mofetil

(MMF) in Patients with MPO-ANCA Microscopic Polyangiitis and Mild to Moderate Renal Dysfunction. (Poster) American Society of Nephrology 2008 Annual Meeting, Philadelphia, PA 2008.

85. Leung N, Shaikh A, Cosio FG, Griffin MD, Gloor JM, Textor SC, Lee CU, Stegall MD,

Pittelkow MR. The Effect of Kidney Transplantation on Nephrogenic Systemic Fibrosis. (Poster) American Society of Nephrology 2008 Annual Meeting, Philadelphia, PA 2008.

86. Leung N, Lee CU, Good JA, Hanley MM, Moyer TP. Chelation of gadolinium with

deferoxamine in a patient with nephrogenic systemic fibrosis. (Poster) American Society of Nephrology 2008 Annual Meeting, Philadelphia, PA 2008.

87. Leung N, Kyle RA, Gertz MA, Zeldenrust SR, Kumar S, Lacy MQ, Fervenza FC, Hayman

SR, Buadi FK, Dispenzieri A. Differences in urine albumin excretion in patients with plasma

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cell dyscrasia related kidney diseases. (Poster) American Society of Nephrology 2008 Annual Meeting, Philadelphia, PA 2008.

88. Naina, HVK, Kyle, R, Habermann TM, Harris, S, Cosio, FG, Stegall, MD, Leung N.

Prevalence of Post-transplant lymphoproliferative disorder with monoclonal gammopathy of unknown significance in patients undergoing kidney transplantation. (Plenary) American Transplant Congress 2008, May 31st – June 4th 2008, Toronto Canada. 2008

89. Naina, HVK, Kyle, R, Habermann TM, Harris, S, Cosio, FG, Stegall, MD, Leung N. Pre

transplantation MGUS and transformation to multiple myeloma in kidney transplantation: A single center experience. (Poster) American Transplant Congress 2008, May 31st – June 4th 2008, Toronto Canada. 2008

90. Amer H and Leung N. Irreversible acute renal failure? Not so fast. (Poster) National Kidney

Foundation 2008 Spring Clinical Meetings, April 2-6, 2008, Dallas TX, 2008 91. El-Zoghby Z and Leung N. Association between sinus histiocytosis and renal cell

carcinoma: A case series. (Poster) National Kidney Foundation 2008 Spring Clinical Meetings, April 2-6, 2008, Dallas TX, 2008

92. El-Zoghby Z and Leung N. Renal cell carcinoma in a 22 year old patient with sinus

histiocytosis. (Poster) National Kidney Foundation 2008 Spring Clinical Meetings, April 2-6, 2008, Dallas TX, 2008

93. Gertz MA, Lacy MQ, Dispenzieri A, Hayman SR, Kumar SK, Buadi F, Leung N, Litzow

MR. Should troponin level be an exclusion criterion for stem cell transplantation in primary amyloidosis. (Poster) American Society of Hematology 2007 Annual Meeting, Atlanta GA, 2007.

94. Kumar SK, Dispenzieri A, Lacy MQ, Hayman SR, Leung N, Zeldenrust SR, Buadi FK, Kyle

RA, Rajkumar V, Gertz MA. Serum uric acid is a novel prognostic factor in patient with primary amyloidosis. (Plenary) American Society of Hematology 2007 Annual Meeting, Atlanta GA, 2007.

95. Sweeting R, Notkin A, Leung N, Ballard H, Pillon L. Approach to Acute Renal Failure in

Biopsy Proven Myeloma Cast Nephropathy. Is There a Role for Plasmapheresis? (Poster) American Society of Nephrology 2007 Annual Meeting, San Francisco CA, 2007.

96. Czarnecki PG, Griffin MD, Lager DJ, Leung N, Stegall M, Fervenza FC. Long-Term

Outcome of Kidney Transplantation (KTX) in Fibrillary Glomerulonephritis. (Poster) American Society of Nephrology 2007 Annual Meeting, San Francisco CA, 2007.

97. Leung N, Zeldenrust SR, Kumar S, Dispenzieri A, Lacy MQ, Gertz MA, Kyle RA, S

Rajkumar SV, and Winters JL. Serum Free Light Chain and Renal Biopsy Accurately Predict Renal Response to Plasma Exchange in Patients with Light Chain Cast Nephropathy. (Poster) American Society of Nephrology 2007 Annual Meeting, San Francisco CA, 2007.

98. Leung N, Zeldenrust SR, Kumar S, Dispenzieri A, Lacy MQ, Gertz MA, Kyle RA, Winters

JL. Plasma exchange is an important and useful adjuvant therapy in cast nephropathy.

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(Poster) The XI International Workshop on Multiple Myeloma. Kos Greece. June 25 – 30th, 2007.

99. Shaikh A and Leung N. Acute renal failure secondary to severe type I cryoglobulinemia

following Rituximab therapy for Waldenstrom’s macroglobulinemia. (Poster) National Kidney Foundation Spring Clinical Meetings. Orlando, FL. April 10-14, 2007.

100. Shaikh A and Leung N. Fanconi’s Syndrome Caused by Capecitabine, Irinotecan and

Bevacizumab.(Poster) National Kidney Foundation Spring Clinical Meetings. Orlando, FL. April 10-14, 2007.

101. Lee C, Hensley G, Leung N, Pittelkow M, Williamson E, Hartman R. Nephrogenic

systemic fibrosis: A multidisciplinary retrospective review and educational exhibit. (Poster) The Society of Uroradiology Meetings. Naples, FL, April 15 – 20th, 2007.

102. Leung N, Dispenzieri A, Lacy MQ, Hayman SR, Kumar S and Gertz MA. Risk Factors

of Treatment Related Mortality during Autologous Stem Cell Transplant in Patients with Light Chain Associated Amyloidosis (AL). (Poster) American Society of Hematology Annual Meeting 2006. Orlando, FL, 2006.

103. Kumar S, Lacy M, Dispenzieri A, Hayman S, Leung N , Rajkumar V, Zeldenrust S, Lust

J, Greipp P, Gastineau D, and Gertz M. Autologous Stem Cell Transplantation for Multiple Myeloma in Patients with Reduced Renal Function: A Matched Set Comparison. (Poster) American Society of Hematology Annual Meeting 2006. Orlando, FL, 2006.

104. Gali B, Keegan MT, Leung N, Findlay JY and Plevak DJ. Continuous renal replacement

therapy during high risk liver transplantation. (Plenary/Poster) 2006 Joint International Congress of the ILTS, ELITA, & LICAGE. Milan, Italy. 2006.

105. Amer H, Leung N, Textor SC. Premature atherosclerosis, acute renal failure and spindle

cell sarcoma: A case presentation. (Poster) National Kidney Foundation 2006 Spring Clinical Meeting. Chicago, IL, 2006.

106. Nyholm B, Gertz MA, Fervenza FC, Haugen EN, Leung N. Characteristics and

Mortality of Patients with primary systemic amyloidosis receiving renal replacement therapy, during the post-stem cell transplant era. (Poster) National Kidney Foundation 2006 Spring Clinical Meeting. Chicago, IL, 2006.

107. Leung N, Dispenzieri A, Lacy MQ, Litzow MR, Kumar SK, Hayman SR. Gertz MA.

Baseline serum albumin and proteinuria predict renal response after autologous stem cell transplantation in AL amyloidosis. (Poster) 47th American Society of Hematology Annual Meeting, Atlanta, GA, 2005.

108. Swaminathan S, Griffin MD, Ahmed I, Pittelkow M, Albright RC, McCarthy TJ, Leung

N. Nephrogenic Fibrosing Dermopathy Is Linked to High Dose Erythropoietin Therapy. (Poster) American Society of Nephrology Annual Meeting, Philadelphia, PA, 2005.

109. Naina HVK, Pflueger A, Leung, N. A case of renal cell carcinoma presenting as focal

segmental glomerulosclerosis (Poster) National Kidney Foundation 2005 Spring Clinical Meeting, Washington D.C., 2005.

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110. Leung N, Leung TR, Dispenzieri A, Lacy MQ, Gertz MA. Excessive Weight Gain during

Mobilization Increases First Year Mortality Following High Dose Therapy and Stem Cell Transplantation in Patients with Primary Amyloidosis. (Poster) 46th American Society of Hematology Annual Meeting, San Diego, CA, 2004.

111. Fervenza FC, Chedid MF, Lager DJ, Leung N, Borza DB. Recurrent Goodpasture’s

Disease Secondary to a Monoclonal IgA-k Antibody Autoreactive with the α1/α2 Chains of Type IV Collagen. (Poster) American Society of Nephrology Annual Meeting, St. Louis, MO, 2004.

112. Swaminathan S, Leung N, Lager DJ, Melton LJ, Bergstralh EJ, Fevenza FC. Changing

Incidence of Glomerulonephritis (GN) in Olmsted County, MN: 30-year Biopsy Study. (Poster) American Society of Nephrology Annual Meeting, St. Louis, MO, 2004.

113. Swaminathan S, Gyamlani G, Buehrig C, McKusick M, Leung N. Transjugular Renal

Biopsy in Patients with Severe Bleeding Tendency. (Poster) American Society of Nephrology Annual Meeting, St. Louis, MO, 2004.

114. Gyamlani G, Buehrig C, Swaminathan S, McKusick M and Leung N. Transjugular

Renal Biospy- Mayo Clinic Experience. (Plenary) North American Society for Dialysis and Transplantation Symposium, Maui, HI, 2004.

115. Leung N, Griffin MD, Dispenzieri A, Gloor JM, Schwab TR, Textor SC, Lacy MQ,

Larson TS, Stegall MD, Gertz MA. The Use of Sequential Living Donor Kidney and Autologous Stem Cell Transplantation for Patients with Primary (AL) Amyloidosis and advanced renal failure. (Poster) 10th International Symposium on Amyloid and Amyloidosis, Tours, Loire Valley, France, 2004.

116. Griffin MD, Leung N, Dispenzieri A, Gloor JM, Schwab TR, Textor SC, Lacy MQ,

Litzow MR, Larson TS, Gertz MA, Stegall MD. Sequential Living Donor Kidney and Autologous Stem Cell Transplantation for AL (“Primary”) Amyloidosis with Predominant Renal Involvement.(Poster) American Transplant Congress, Boston, MA, 2004.

117. Cauduro SP, Hay JE, Leung N. Recovery of renal function with liver transplantation in

hepatorenal syndrome. (Plenary) 18th meeting of the Latin American Association for the Study of the Liver, Salvador, Bahia, Brazil, 2004.

118. Gertz MA, Leung N, Lacy MQ, Dispenzieri A. Delayed Resolution of Nephrotic

Syndrome Following Stem Cell Transplant for Amyloidosis (AL). (Plenary) 45th American Society of Hematology Annual Meeting, San Diego, CA, 2003.

119. Xu N, Dingli D, Leung N, Lust JA. Nephrogenic diabetes insipidus, a rare complication

of paraproteinemia. (Poster) American College of Physicians, Minnesota Chapter Scientific Meeting, Brooklyn Park, MN, 2003.

120. Leung N, Slezak JM, Bergstralh EJ, Gertz MA. The Impact of Post Conditioning Renal

Insufficiency on Patients with Primary Systemic Amyloidosis Undergoing Peripheral Blood Stem Cell Transplantation and its Risk Factors. (Poster) 35th American Society of Nephrology Annual Meeting, Philadelphia, PA, 2002.

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121. Villicana R, Leung N, Gertz MA. Long Term Renal Outcome of Peripheral Blood Stem

Cell Transplantation on Primary Systemic (AL) Amyloidosis. (Poster) 35th American Society of Nephrology Annual Meeting, Philadelphia, PA, 2002.

122. Leung N, Croatt AJ, Nath KA. Bile Duct Ligation (BDL) confers a novel form of

acquired resistance to acute renal failure (ARF): Putative role of bilirubin. (Plenary) 33rd American Society of Nephrology Annual Meeting, Toronto, Canada, 2000.

123. Leung N, Croatt AJ, Nath KA. Heme oxygenase-1 (HO-1) is induced in the kidney in the

bile duct ligation model (BDL) of acute renal insufficiency (ARI) and influences renal function. (Poster) 32nd American Society of Nephrology Annual Meeting, Miami, FL, 1999.

Miscellaneous

1. Appel G, Leung N, Rajkumar SV. Pathogenesis and diagnosis of myeloma cast nephropathy

(myeloma kidney). UpToDate 2007 to present.

2. Leung N, Appel G, Kyle RA. Renal Amyloidosis. UpToDate 2007 to present.

3. Leung N, Appel G, Rajkumar SV. Types of Renal Disease in Multiple Myeloma. UpToDate 2007 to present.

4. Rajkumar SV, Kaplan A, Leung N. Treatment of Kidney disease in multiple myeloma. UpToDate 2007 to present.

5. Leung N. Myeloma Kidney, AskMayoExpert-Nephrology & Hypertension topic, Mayo Clinic 2009. AskMayoExpert 2009.

6. Leung N. Renal Amyloidosis, AskMayoExpert-Nephrology & Hypertension topic, Mayo Clinic 2009. AskMayoExpert 2009.

Forthcoming