curriculum vitae alexander gottschalk, m.d

CURRICULUM VITAE Alexander Gottschalk, M.D.

Born: Married: Education: Academic Honors: Internship: Residency: Current Licensure: Prior Licensure: Certification: Special Awards: Selected Name Lectures:

March 23, 1932, Chicago, Illinois Jane Rosenbloom – three children B.A., 1954, Harvard College, Magna Cum Laude. John Harvard Scholarship Award (hon.) for excellence M.D., 1958, Washington University Medical School, St. Louis, Missouri Phi Beta Kappa -- Harvard Alpha Omega Alpha – Washington University, St. Louis University of Illinois Research and Educational Hospitals, (1958-1959) University of Chicago (Radiology), July 1959 – June 1962 State of Michigan State of Illinois State of California State of Connecticut American Board of Radiology, June 1963 American Board of Nuclear Medicine, May 1973 American Board of Radiology – Special Competence in Nuclear Medicine, June

1974 Selected as one of America’s Ten Outstanding Young Men of 1967 (by U.S.

Jaycees) Recipient of 1987 Gold Medal of the Association of University Radiologists Recipient of The Most Significant Manuscript of 1993 Award (by J Nuc Med) Excellence Award – Paul C. Hodges Alumni Society. University of Chicago

Radiology Department, November, 1999 Recipient of the RSNA Gold Medal Award, 2004 Recipient of the Ben Cassen Award, 2006, The Society of Nuclear Medicine Alumni Achievement Award, Washington University, St. Louis School of

Medicine, May 2008 Ross Golden Lecture (New York Roentgen Society) April, 1974 Fleischner Lecture (Fleischner Society) May, 1983 Philip M. Johnson Memorial Lecture (Columbia University) May, 1984 First Daniel M. Biello Lecture (Washington University) April, 1987 Milton B. Kress Memorial Lecture (Maryland Society of Nuclear Medicine) April, 1988 J. Ralph Jamieson Memorial Lecture (Canadian Association of Nuclear Medicine)

September, 1988 Herbert M. Stauffer Lecture (Temple University) May, 1995

National Consultantships: Society Memberships: Offices Held:

National Heart Institute – Urokinase, Streptokinase Pulmonary Embolism Trial. Member – Lung Scan Analysis Panel, 1967-1973

National Institutes of General Medicine Sciences – Radiology Training

Committee, Research Training Grants Branch, 1970-1973 FDA Advisory Committee on Radiopharmaceuticals, 1970-1974 Steering Committee – NHLBI Prospective Investigation of Pulmonary Embolism

(PIOPED) Multicenter National Trial, 1985-1990 Radiology Residency Review Committee of the ACGME (American College of

Radiology Representative), 1987-1994 American College of Chest Physicians (Fellow) American College of Radiology (Fellow) American Medical Association American Roentgen Ray Society Association of Program Directors in Radiology Association of University Radiologists Fleischner Society Radiological Society of North America Society of Nuclear Medicine Secretary-Treasurer Association of University Radiologists 1968-69 President Association of University Radiologists 1969-71 Trustee Society of Nuclear Medicine 1969-73 President Central Chapter, Society of Nuclear Medicine 1970-71 Chairman, Nuclear Medicine Program Committee Radiological Society of North America 1970-76 President Society of Nuclear Medicine 1974-75 Executive Committee Chicago Radiological Society 1973-74 President Society of Nuclear Medicine 1974-75 Second Vice President Radiological Society of North America 1977

Revised 5/13/08 2 Alexander Gottschalk, M.D.

Board Certification Activities: Current or Past Editorial Boards: Academic Positions

Treasurer The Fleischner Society 1978-83 President The Fleischner Society 1989-90 Chairman Radiology Residency Review Committee (ACGME) 1990-93 Vice Chairman Residence Review Chairman’s Council 1991-92 Member, American Board of Nuclear Medicine 1973-78 Life Member, American board of Nuclear Medicine 1978 Guest Examiner, American Board of Radiology Past Member, Executive Editorial Committee • Member, Editorial Board, Investigative Radiology Past Member, Editorial Board • Journal of Molecular Medicine Yearbook of Nuclear Medicine • Year Book of Nuclear Medicine (Yearbook Publishers Gold

Medal for Excellence) 1981-93 Editor-in-Chief Year Book of Nuclear Medicine 1994-2003 Research Associate (Radiology) Donner Laboratory, Lawrence Radiation Lab University of California at Berkeley Berkeley, California July 1962-June 1964 Assistant Professor of Radiology Department of Radiology University of Chicago Chicago, Illinois July 1964-June 1966 Faculty Research Associate American Cancer Society July 1965-July 1967 Chief, Section of Nuclear Medicine Department of Radiology University of Chicago Chicago, Illinois July 1964-January 1971 Associate Professor of Radiology Department of Radiology University of Chicago Chicago, Illinois April 1966-October 1968



Professor of Radiology Department of Radiology University of Chicago Chicago, Illinois November 1968-September 1974 Director of the Argonne Cancer Research Hospital (later known as Franklin McLean Institute) University of Chicago Hospitals and Clinics April 1967-June 1974 Chairman, Department of Radiology University of Chicago Chicago, Illinois July 1971-November 1972 Professor of Diagnostic Radiology Yale University School of Medicine New Haven, Connecticut September 1974-September 1990 Director, Section of Nuclear Medicine Yale University School of Medicine New Haven, Connecticut September 1974-October 1977 Vice Chairman, Department of Diagnostic Radiology Yale University School of Medicine New Haven, Connecticut May 1977-June 1989 Acting Chairman, Department of Diagnostic Radiology (Dr. Greenspan on Sabbatical) Yale University School of Medicine New Haven, Connecticut July 1980-June 1981 Director, Diagnostic Radiology Residency Program Yale University School of Medicine New Haven, Connecticut May 1985-June 1989 Visiting Professor, Radiology Michigan State University (Sabbatical leave) East Lansing, Michigan June 1989-May 1990 Professor, Diagnostic Radiology Michigan State University East Lansing, Michigan September 1990-present Director, Diagnostic Radiology Residency Program University Affiliated Hospitals of Flint (FAME) February 1991-2000 Director, Diagnostic Radiology Residency Program Grand Rapids Program (GRAMEC) February 1991-January 2000

Books and Book Chapters 1. Gottschalk A and Anger HO: Progress in Radioisotope Scanning: Clinical Application of Scintillation

Camera. Chapter 4 in Progress in Atomic Medicine, Vol. I, John H. Lawrence, Editor. Grune & Stratton, New York, 1965. pp. 78-106.

2. D’Angio GJ, Gottschalk A, Lawrence JH: Medical Applications of High Energy Nuclear Particles.

Nuclear Medicine, William H. Blahd, Editor, McGraw-Hill, New York, 1965, pp. 779-798. 3. Harper PV, Lathrop KA, Gottschalk A: Pharmacodynamics of Some Technetium-99m Preparations.

Radioactive Pharmaceuticals. Editors, Andrews GA, Kinseley RM, and Wagner, Jr., HN, USAEC CONF-651111, Chapter 18, pp. 335-385, April, 1966.

4. Harper PV, Gottschalk A, Charleston DB, Yasillo N: Area Scanning with the Anger Camera.

Fundamental Problems in Scanning, Editors, Gottschalk A, and Beck RH, Charles C. Thomas, Springfield, Illinois, Fall, 1968, Chapter 9, pp. 145-147.

5. Gottschalk A, Beck RN: Editors, Fundamental Problems in Scanning. Charles C. Thomas, Springfield,

Illinois, Fall 1968. 6. Gottschalk A: Modulation Transfer Function Studies for the Scintillation Camera. Fundamental

Problems in Scanning, Editors, Gottschalk A, and Beck, RN, Charles C. Thomas, Springfield, Illinois , Fall 1968, Chapter 27, pp 314-325.

7. Harper PV, Gottschalk A, Beck RN: Recent Advances in Scanning, Chapter 6 in Progress in Atomic

Medicine, Vol 2, John H. Lawrence, Editor. Grune & Stratton, New York, 1968, pp. 168-183. 8. Harper PV, Gottschalk A: Charleston DB, and Yasillo NJ, Area Scanning with the Anger Camera.

Fundamental Problems in Scanning. Editors, Gottschalk A, Beck RN, Charles C. Thomas, Springfield, Illinois, Fall, 1968, Chapter 9, pp. 145-147.

9. Gottschalk A: Technetium-99m in Clinical Nuclear Medicine. Annual Review of Medicine, Vol. 20,

Editor, Arthur C. DeGraff. Annual Review, Inc., Palo Alto, California, 1969, pp. 131-140. 10. Gottschalk A: Bone Scanning. Chapter in Proc. Symposium in Nuclear Medicine – Its current status in

Medical Practice, Cleveland, Ohio, September, 1967. USAEC Conf-670958, 1969, pp. 88-97. 11. Gottschalk A: Prospective. Chapter 17 in Clinical Scintillation Scanning. Editors, Leonard M.

Freeman and Philip M. Johnson. Hoeber Medical Division, Harper & Row, New York, 1969, pp. 508-521.

12. Gottschalk A: What do cameras see? Presented at 2nd Annual Meeting of Nuclear Medicine Seminar

19-23, January 1970, Miami Beach. Central Nervous System Investigation with Radionuclides. Editors, Gilson, AJ, and Smoak, WM, Charles C. Thomas, Publisher, Springfield, Illinois, pp. 165-174.

13. Gottschalk A: High Resolution Rectilinear Brain Scanning. Is It Worth the Effort? Ibid, pp. 253-261. 14. Gottschalk A, Ariel IM: Hepatic Scanning in the Diagnosis of Liver Abscesses. Publisher, Williams

and Wilkins Company, Baltimore, Maryland. Edited by Irving M. Ariel, M.D., F.A.C.S., and Kirk K. Kazarian, M.D., 1971.


15. Hoffer PB, Beck RN, Gottschalk A: Editors, Semiconductor Detectors in the Future of Nuclear Medicine. Published by the Society of Nuclear Medicine, Inc., New York, NY, 1971.

16. Hoffer PB, Beck RN, Gottschalk A: (Ed.): The Effect of Minimization of Scatter Using GE(Li)

Detectors on Phantom Models and Patients in Semiconductor Detectors in Nuclear Medicine. The Society of Nuclear Medicine, pp. 131-143, July 1971.

17. Hoffer PB, Beck RN, Gottschalk A: Clinical Results in Fluorescent Thyroid Scanning , Semiconductor

Detectors in the Future of Nuclear Medicine. The Society of Nuclear Medicine, pp. 230-239, July 1971. 18. Gottschalk A: Renal Scanning Agents. Principles of Diagnostic Radiology. Editors, Potchen, Koehler,

Davis, Publisher, McGraw-Hill, Inc., 1971, pp. 54-58. 19. Gottschalk A: Liver Scanning. Principles of Diagnostic Radiology. Editors, Potchen, Koehler, Davis,

Publisher, McGraw-Hill, Inc., 1971, pp. 72-74. 20. Rosenfield RL, Refetoff S, Hoffer PB: Gottschalk A, DeGroot LG, Chapter 10, Endocrine Glands,

Pediatric Nuclear Medicine, (Eds.), James, Wagner, and Cooke, W.B. Saunders Co., Philadelphia, Pennsylvania, pp. 376-399, 1994.

21. Larson KB, Cox JF Jr: Editors, Gottschalk A, Contributor, and Others, Computer Processing of

Dynamic Images from an Anger Scintillation Camera. The Society of Nuclear Medicine, Inc., New York, 1974.

22. Hoffer PB, Gottschalk A: Clinical Scintigraphic Scanning, Prospective Section, Chapter in Clinical

Scintillation Scanning, 2nd Edition, (Ed.), Freeman L, Johnson PM, Grune & Stratton, 1975, pp. 755-764.

23. Gottschalk A, Hoffer PB: Stationary Detectors. Diagnostic Nuclear Medicine, Ross Golden Series in

Diagnostic Radiology, Editors, Gottschalk A, Potchen EJ, The Williams & Wilkins, Co., Baltimore, Maryland, 1976.

24. Hoffer PB, Gottschalk A, Harris CC: Factors Which Influence the Choice of an Instrument. Diagnostic

Nuclear Medicine, Ross Golden Series in Diagnostic Radiology, Editors, Gottschalk A, Potchen EJ, The Williams & Wilkins, Co., Baltimore, Spring, 1976.

25. Hoffer PB, Gottschalk A, Quinn JL: Thyroid In Vivo Studies. Diagnostic Nuclear Medicine, Ross

Golden Series in Diagnostic Radiology. Editors, Gottschalk A, Potchen EJ. The Williams & Wilkins Co., Baltimore, 1976.

26. Heck L, Gottschalk A, Hoffer PB: Static and Dynamic Brain Imaging, Diagnostic Nuclear Medicine,

(Eds.) Gottschalk A, Potchen EJ, Robbins LL, Williams & Wilkins Co., Baltimore, Maryland, 1976. 27. Oppenheim BE, Gottschalk A, Hoffer PB: Liver Scanning. Diagnostic Nuclear Medicine, Ross Golden

Series in Diagnostic Radiology. Editors, Gottschalk A, Potchen EJ. The Williams & Wilkins Co., Baltimore, 1976.

28. Landman S, Gottschalk A: Pancreas Scans. Diagnostic Nuclear Medicine, Ross Golden Series in

Diagnostic Radiology. Editors, Gottschalk A, Potchen EJ. The Williams & Wilkins Co., Baltimore, 1976.


29. Gottschalk A: Tumor Scanning of Lymphomas. Diagnostic Nuclear Medicine, Ross Golden Series in Diagnostic Radiology. Editors, Gottschalk A, Potchen EJ. Williams & Wilkins Co., Baltimore, Spring, 1976.

30. Gottschalk A, Potchen EJ: Editors, Diagnostic Nuclear Medicine, Ross Golden Series in Diagnostic

Radiology. The Williams & Wilkins Co., Baltimore, Spring, 1976-1982. 31. Berger HJ, Gottschalk A, Zaret BL: First-Pass Radionuclide Angiocardiography for Evaluation of Right

and Left Ventricular Performance: Computer Application and technical Considerations. In Selected Computer Aspects of Nuclear Cardiology. R. Sorensen, ed., Society of Nuclear Medicine, New York, pp. 29-44,1978.

32. Berger HJ, Gottschalk A, Zaret BL: Cardiovascular Nuclear Medicine in the Assessment of the

Intensive Care Unit Patient. Radiographic Evaluation of the Intensive Care Unit Patient, (Eds.), Goodman and Putman, CV Mosby.

33. Margulis AR, Burhenne HJ: Editors, Alimentary Tract Roentgenology – Vol. III Abdominal Imaging.

Sullivan D, Gottschalk A, Part II. Liver and Biliary Tract. The CV Mosby Co., 1979. 34. Caride JV, Gottschalk A: Nuclear Imaging, Current Radiology. Editor, Wilson, Handfee G, W.N.

Noughton Misslin Pub. 1979, Chapter 8. 35. Simon TR, Gottschalk A: The Thyroid Gland. In: Surgical Radiology. Eds. Teplick JG, Haskin ME.

W.B. Saunders Philadelphia, London, Toronto, Vol. 3 pp. 2060-2089, 1981. 36. Zaret B, Davies R, Thakur M, Berger H, Wakers F, Gottschalk A: Imaging the inflammatory response

to acute myocardial infacrtion. In Indium-111 Labeled Nuetrophils, Platelets, and Lymphocytes. (Thakur M, Gottschalk A, Eds) NY, Trivirum Publishers, 1981, pp. 59-166.

37. Thakur ML, Gottschalk A: The role of Radiopharmaceuticals in Nuclear Hematology. Proceedings of

the 2nd International Symposium on radiopharmaceuticals. The Society of Nuclear Medicine, 314-353, 1979.

38. Berger H, Gottschalk A, Zaret B: Radionuclide assessment of left ventricular performance. In,

Radiologic Clinics of North America 18:441-466, 1980. 39. Berger H, Gottschalk A, Zaret B: Nuclear Medicine procedures. In Cardiac Imaging in Infants and

Children (Kelley MJ, Kleinman C, Jaffe CC, Eds.), New York, Philadelphia, W. Saunders, 1982, pp. 112-154.

40. Thakur M, Gottschalk A: Editors, Indium-111 Labeled Neutrophils, Platelets, & Lymphocytes,

Proceedings of the Yale Symposium: Radiolabeled Cellular Blood Elements – Current Accomplishments, Immediate Potential and Future Possibilities. Trivirum Publishing Co., New York, 1980, pp.83-92.

41. Thakur ML, Gottschalk A: Experience with Induum-111-Oxine. Chapter 5 in, Indium-111 Labeled

Neutrophils, Platelets, & Lymphocytes, Editors, Thakur M, Gottschalk A, Trivirum Publishing Co., New York, 1980, pp. 41-50.


42. Zakhireh B, Thakur ML, Malech HL, Cohen MS, Gottschalk A, Root R: In Vitro Function of Indium-111-Labeled Human Polymorphonuclear Leukocytes. Chapter 9 in Indium-111-Labeled Neutrophils, Platelets, & Lymphocytes, Editor, Thakur M and Gottschalk A, Trivirum Publishing Co., New York, 1980, pp. 83-92.

43. Zaret BL, Davies RE, Thakur M., Berger HJ, Wackers FJ, Gottschalk A: Imaging the Inflammatory

Response to Acute Myocardial Infarction. Chapter 16 in Indium-111 Labeled Neutrophils, Platelets, & Lymphocytes, Editors, Thakur M and Gottschalk A, Trivirum Publishing Co., New York, 1980, pp. 151-158.

44. Riba AL, Thakur ML, Gottschalk A, Zaret BL: Indium-111-Platelet Imaging of Experimental Intra-

Cardiac Thrombosis. Chapter 16 in Indium-111 Labeled Neutrophils, Platelets & Lymphocytes, Editors, Thakur M and Gottschalk A, Trivirum Publishing Co., New York, 1980, pp. 159-166.

45. Riba AL, Thakur ML, Gottschalk A, and Zaret BL: Detection of cardiovascular disorders with In-111

labeled platelets, page 55 in Platelets and Prostaglandin’s in Cardiac Diseases. Ed. Mehta J and Mehta P, Future Pub. Co., New York, 1981.

46. Neumann RD, Hoffer HB, Merino MJ, Kirkwood JM, Gottschalk A: Clinical value of gallium-67 in

imaging patients with lung carcinoma and melanoma. IAEA-SM-247/93, pp. 475-486, 1981. 47. Hoffer P, Gottschalk A, Zaret B: editors 1981 Year Book of Nuclear Medicine, Year Book Medical

Publishers, Inc.; Chicago. London, 1981. 48. Berger HJ, Gottschalk A, Zaret BL: Nuclear Medicine Procedures. In: Cardiac Imaging in Infants and

Children, Editors Kelley M, Jaffe C, and Kleinman C, W.B. Saunders Co., Philadelphia, 1982, pp. 112-154.

49. Hoffer P, Gottschalk A, Zaret B: Editors 1982 Year Book of Nuclear Medicine, Year Book Medical

Publishers, Inc.; Chicago. London, 1982. 50. Hoffer PB, Gottschalk A, Siegel B, Freeman L, Strauss W, Kuni CC: Nuclear Medicine. In: Tumor

Imaging, Ed. D. Bragg and W. Hendee, Appleton-Century-Crofts, Norwalk, CT, 1982, pp. 39-47. 51. Berger HJ, Riba AL, Gottschalk A, and Zaret BL: Cardiovascular Nuclear Medicine and

Ultrasonography. In: Intensive Care Radiology: Imaging of the Critically Ill, Ed. Goodman LR and Putman CE, W.B. Saunders Co., Philadelphia, 1983, pp. 237-264.

52. Margulis AR, Burhenne HJ: Editors, Alimentary Tract Roentgenology – Vol. III Abdominal Imaging.

Sullivan D, Gottschalk A, Part II. Liver and biliary Tract. The C.V. Mosby Co., 1983. 53. Gottschalk A: Positron and Single Photon Tomography in Nuclear Medicine. Sectional Imaging

Methods: A Comparison, Ed. Littelton JT, Durizch ML, University Park Press, Baltimore, 1983, pp. 59-66.

54. Hoffer P, Gottschalk A, Zaret B: Editors 1983 Year Book of Nuclear Medicine, Your Book Medical

Publishers, Inc.; Chicago. London, 1983. 55. Sostman D, Rapport S. Glickman M, Gottschalk A: Problems in Non-invasive Imaging of Pulmonary

Embolism. Radiologic Clinics of North America, Vol. 21, No. 4, December, 1983.


56. Hoffer P, Gottschalk A, Zaret B: Editors 1984 Year Book of Nuclear Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1985.

57. Hoffer P, Gore J, Gottschalk A, Sostman D, Zaret B: Editors 1985 Year Book of Nuclear Medicine,

Year Book Medical Publishers, Inc.; Chicago. London, 1985. 58. Gottschalk A: Tumor imaging and monoclonal antibody imaging. Categorical Course in Nuclear

Medicine. Presented at the 71st Scientific Assembly and Annual Meeting of the Radiological Society of North America , November, 1985, pp. 105-109. Syllabus.

59. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B: Editors 1986 Year Book of Nuclear Medicine,

Year Book Medical Publishers, Inc.; Chicago. London, 1986. 60. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B: Editors 1987 Year Book of Nuclear Medicine,

Year Book Medical Publishers, Inc.; Chicago. London, 1987. 61. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B, Zubal I: Editors 1988 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1988. 62. Stostman HD, Alderson PO, Gottschalk A: Nuclear medicine techniques and application. In: Textbook

of respiratory Medicine, Williams & Wilkins Publishers, Baltimore, 1988. 63. Gottschalk A, Hoffer PB, Potchen EJ (Eds.) Golden’s Diagnostic Radiology, 2nd Edition, Diagnostic

Nuclear Medicine, Williams & Wilkins Publishers, Baltimore, 1988. 64. Stostman HD, Gottschalk A: Detection of pulmonary emboli. In: Golden’s Diagnostic Radiology, 2nd

Edition, Diagnostic Nuclear Medicine, Gottschalk A, Hoffer PB, Potchen EJ (Eds.), Williams & Wilkins Publishers, Baltimore, 1988, Vol. 2, pp. 502-521.

65. Gagliardi P, Berg BC, Gottschalk A: Use of radionuclide imaging in diagnosis and management of the

acute trauma patient. In: Golden’s Diagnostic Radiology, 2nd Edition, Diagnostic Nuclear Medicine, Gottschalk A, Hoffer PB, Potchen EJ (Eds.), Williams & Wilkins Publishers, Baltimore, 1988, Vol. 2, pp. 1137-1149.

66. Gottschalk A, Cornelius E, and Hoffer PB: Sensitivity and efficacy indices for oncologic data reporting.

In: Radiolabeled Monoclonal Antibodies for Imaging and Therapy. Editor, SC Srivastava, Plenum Publishing Corporation, New York, pp. 139-145, 1988.

67. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B, Zubal I: Editors 1989 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1989. 68. Potchen EJ, Haacke EM, Siebert JE, Gottschalk A. Magnetic resonance Angiography. (Editors)

Mosby, St. Louis, 1992. 69. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B, Zubal I: Editors 1990 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1990. 70. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B, Zubal I: Editors 1991 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1991. 71. Hoffer P, Gore J, Gottschalk A, Stostman D, Zaret B, Zubal I: Editors 1992 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1992. Revised 5/13/08 9 Alexander Gottschalk, M.D.

72. Hoffer P, Gore J, Gottschalk A, Rattner Z, Zaret B, Zubal I: Editors 1993 Year Book of Nuclear

Medicine, Year Book Medical Publishers, Inc.; Chicago. London, 1993. 73. Hoffer PB, Blaufox MD, Brown M, Eckelman WC, Gore JC, Gottschalk A, Rattner Z, Waxman A,

Zaret BL, Zubal IG: Editors 1994 Year Book of Nuclear Medicine, Year Book Medical Publishers, Inc.; Chicago, London, 1994.

74. Gottschalk A, Alderson PO, Stostman HD; Nuclear Medicine techniques and Applications, Textbook of

Respiratory Medicine, Second Edition, (two volume set). W.B. Saunders Company 1995. 75. Gottschalk A: Editor in Chief; Year Book of Nuclear Medicine, Year Book Medical Publishers, Inc.;

Chicago. London, 1995. 76. Sandler MP, Coleman RE, Wackers FJTH, Patton JA, Gottschalk A, Hoffer PB: Diagnostic Nuclear

Medicine, Third Edition, (two volume set). Williams & Wilkins, 1995. 77. Gottschalk A: Editor in Chief; 1996 Year Book of Nuclear Medicine, Year Book Medical Publishers,

Inc.; Chicago. London, 1996. 78. Gottschalk A, Bisesi MA, Stein PD: Ventilation-perfusion Lung Scans for the Diagnosis of Acute

Pulmonary Embolism. In: Disorders of Thrombosis, First Edition, Hull R, Pineo GF (Eds), W.B. Saunders Publisher, Philadelphia, 1996, Chapter 24, pp. 258-271.

79. Gottschalk A, Bisesi MA, Stein PD: Ventilation-perfusion Lung Scans for the Diagnosis of Acute

Pulmonary Embolism. In: Venous Thromboembolism: An Evidence-Based Atlas, First Edition, Hull RD, Raskob GE, Pineo GF (Eds), Future Publishing Co., Armonk, NY, 1996, Chapter 22, pp. 169-182.

80. Gottschalk A: Editor in Chief; 1997 Year Book of Nuclear Medicine, Year Book Medical Publishers,

Inc.; Chicago. London, 1997. 81. Gottschalk A: Editor in Chief; 1998 Year Book of Nuclear Medicine, Year Book Medical Publishers,


Inc.; Chicago. London, 1999. 83. Worsley D, Gottschalk A: Nuclear Medicine Techniques and Applications, Textbook of Respiratory

Medicine, Third Edition, (two volume set). W.B. Saunders Company, 2000. 84. Gottschalk A: Editor in Chief; 2000 Year Book of Nuclear Medicine, Year Book Medical Publishers,



Inc.; Chicago. London, 2002. 87. Sandler MP, Coleman RE, Patton JA, Wackers FJTh, Gottschalk A; Diagnostic Nuclear Medicine,

Fourth Edition, Chapter 18, Lippincott Williams & Wilkins, 2003. Revised 5/13/08 10 Alexander Gottschalk, M.D.

88. Gottschalk A: Editor in Chief; 2003 Year Book of Nuclear Medicine, WB Saunders Company, Elsevier Science, 2003.

Published Abstracts 1. Gottschalk A: Diagnostic uses of the scintillation camera. J Nucl Med 5:371, 1964. 2. Anger HO, Gottschalk A, VanDyke DC: Progress in the clinical use of the scintillation camera. J Nucl

Med 5:385, 1964.

3. Petasnick JP, Gottschalk A: Spleen scanning with technetium-99m sulfur colloid and the scintillation camera. J Nucl Med 6:362, 1965.

4. Gottschalk A, Lathrop KA, Harper PV: Technetium-99m iron complex as a renal scanning agent. J

Nucl Med 7:373, 1966.

5. Harper PV, Gottschalk A, Charleston DB, Yasillo N: Area scanning with the Anger camera. J Nucl Med 7:373, 1966.

6. Polcyn RE, Poteshman NL, Gottschalk A: Isotope angiocardiography with technetium-99m and the

scintillation camera. J Nucl Med 7:374, 1966.

7. Gottschalk A, Ranniger K, Paloyan D, Paloyan E, and Harper PV: Bilateral intra-arterial injection of the thyrocervical trunk: A technique to facilitate localization of parathyroid adenomas with selenium-75-methionine. J Nucl Med 7:374, 1966.

8. Polcyn RE, Lambeth JT, Hendricks KO, Gottschalk A: The 1600 channel analyzer-gamma camera

combination for evaluation of organ configuration and function. J Nucl Med 8:312, 1967

9. Lathrop KA, Harper PV, Gottschalk A, Beck RN, Hinn GM, Finston P, Cohen TD: Comparative evaluation of Technetium-99m, Gallium-68, and Indium-113 for liver, lung, kidney and brain visualization. J Nucl Med 8:301, 1967.

10. Henricks KO, Lambeth JT, Gottschalk A: Correlation of cerebral blood flow dynamics with the time

lapse scintiphotography using the gamma camera with multichannel analyzer. J Nucl Med 8:263, 1967.

11. Gottschalk A, Cohen T, Beck RN: Optimization of spectrum analysis for pancreas and parathyroid

scanning with Selenium-75. J Nucl Med 8:321, 1967.

12. Paloyan D, Henricks KO, Gottschalk A, Harper PV: Early thyroid uptake measurements using the gamma scintillation camera – 1600 channel-analyzer. J Nucl Med 8:336, 1967.

13. Gottschalk A, Abatie JD, Petasnick JP, Polcyn RE, Beck RN, Charleston DB: The comparison between

sensitivity and resolution based on a clinical evaluation with the ACHR brain scanner. J Nucl Med 9:320, 1968.

14. Hoffer PB, Charleston DB, Beck RN, Gottschalk A: Fluorescent thyroid scanning without the use of

radioactive nuclides in vivo. J Nucl Med 9:324, 1968. Revised 5/13/08 11 Alexander Gottschalk, M.D.

15. Polcyn RE, Quinn JL III, Gottschalk A: Liver scan artifacts. J Nucl Med 9:342, 1968.

16. Reddy M, Harper PV, Gottschalk A, Polcyn RE: Approaches to the problem of noise in 99m-Tc liver

scans. J Nucl Med 9:43, 1968.

17. Heck L, Latrhrop K, Gottschalk A, Harper PV, Fultz M: Perchlorate washout of pertechnetate from the thyroid gland. J Nucl Med 10:323, 1968.

18. Gottschalk A, Usher MS, Polcyn RE, Quinn JL III: Scintillation camera with diverging collimator:

Physical parameters and a clinical evaluation. J Nucl Med 10:337, 1969.

19. Kranzler JK, Harper PV, Polcyn RE, Gottschalk A: The scintiphotographic demonstration of hepatic pliability as a diagnostic criterion. J Nucl Med 10:416, 1969.

20. Gottschalk A: Tumor localization with the gamma camera. Presented at 10th International Cancer

Congress, Houston, Texas 22-29, May, 1970.

21. Heck LL, Gottschalk A: Rapid and reproducible method for 99m-Tc thyroid uptakes. J Nucl Med 11(6):325, 1970.

22. Hoffer PB, Beck RN, Charleston DB, Zimmer LT, Gottschalk A: Use of lithium-drifted germanium

detectors for clinical radioisotope scanning. J Nucl Med 11(6):326, 1970.

23. Hoffer PB, Gottschalk A, Foster J: Fluorescent thyroid scanning (scanning with radioisotopes): Initial clinical results. J Nucl Med 11(6):326, 1970.

24. Landman S, Polcyn RJ, Gottschalk A: Pancreas scanning – is it worth it? J Nucl Med 11(6):393, 1970

25. Hoffer PB, Bernstein J, Beck RN, Gottschalk A: Fluorescent thyroid scanning: A progress report. J

Nucl Med 12(6):366, 1971

26. Pinsky SM, Hoffer PB, Kinnas NC, Gottschalk A: Value of bone marrow scanning in the staging of Hodgkin’s disease. J Nucl Med 12(6):395, 1971.

27. Tetalman MR, Heck LL, Hoffer PB, Kunzmann A, Gottschalk A: Appearance of the inhalation lung

scan in normal individuals. J Nucl Med 12(6):467, 1971.

28. Tetalman MR, Hoffer PB, Heck LL, Kunzmann A, Gottschalk A, Webber MM, Reznick L, Cragin M, and Victery W: Appearance of the lung scan in normal individuals. J Nucl Med 12(6):401, 1971.

29. Yasillo N, Charleston DB, Rutkowskey GF, Hoffer PB, Gottschalk A: Multiframe recording from a

scintillation camera on 8x10 sheet film. J Nucl Med 12(6):473, 1971.

30. Tetalman MR, Heck LL, Hoffer PB, Kunzmann A, Gottschalk A: The appearance of the perfusion and inhalation lung scan in normal individuals. Invest Radiol 6:346, 1971.

31. Tetalman MR, Oppenheim BE, Hoffer PB, Beck RN, Gottschalk A, Anderson TM, Chiles JT, Adkins J,

Yasillo N, Kulberg GH: Evaluation of a new low-energy diverging collimator. J Nucl Med 13(6):474, 1972.


32. Turner DA, Gottschalk A, Hoffer PB, Ultmann JE, Harper PV: 67-Ga scanning in the staging of malignant lymphoma: Successes and failures. J Nucl Med 13(6):474, 1972.

33. Chiles JT, Mintzer RA, Hoffer PB, Gottschalk A: Documentation of a splenic displacement and

changes in splenic size. J Nucl Med 14(6):386, 1973.

34. Pinsky SM, Gottschalk A, Que YL, Johnson MC: Lung overlap sign in combined liver-lung scanning. J Nucl Med 14(6):438, 1973.

35. Beckerman C, Gottschalk A, Hoffer PB: Optimal time for total body imaging to detect metastateic

thyroid carcinoma. J Nucl Med 51(6):477, 1974.

36. Gottschalk A, Oppenheim BE, Beckerman C, Hoffer PB: Advanced liver imaging. J Nucl Med 15(6):496, 1974.

37. Marshall RC, Freedman GS, Costin JC, Cohen LS, Gottschalk A, Zaret BL: Determination of left

ventricular ejection fraction and regional wall motion from first-pass radionuclide angiocardiograms using a computerized multi-crystal scintillation camera. J Nucl Med 17:555, 1976.

38. Marshall RC, Freedman GS, Berger HJ, Wolberg J, Cohen LS, Gottschalk A, Zaret BL: Left ventricular

contractility as assessed by normalized ejection velocity utilizing quantitative radionuclide angiocardiography and a computerized multi-crystal scintillation camera. J Nucl Med 17:555, 1976.

39. Marshall RC, Costin JC, Berger HJ, Freeman GS, Wolberg J, Gottschalk A, Cohen LS, Zaret BL: Non-

invasive radionuclide technique for left ventricular contractility and pump function in man. Clin Res 24:229A, 1976.

40. Berger HJ, Matthay RA, Marshall RC, Gottschalk A, Cohen LS, Zaret BL: Non-invasive radionuclide

technique for right ventricular ejection fraction in man. Circulation 54:II-109, 1976.

41. Marshall RC, Berger HJ, Costin JC, Freedman GS, Wolberg J, Cohen LS, Gottschalk A, Zaret BL: Non-invasive radionuclide assessment of left ventricular ejection velocity in man. Circulation 54:II-218, 1976.

42. Berger HJ, Matthay RA, Gottschalk A, Zaret BL: Effects of animophylline on right and left ventricular

performance in chronic obstructive pulmonary disease: Assessment by quantitative radionuclide angiocardiography. Clin Res 25:209A, 1977.

43. Matthay RA, Berger HJ, Loke J, Gottschalk A, Zaret BL: Clinical and physiologic correlates of right

ventricular ejection fraction in chronic obstructive pulmonary disease: Assessment by quantitative radionuclide angiocardiography. Clin Res 25:420A, 1977.

44. Marshall RC, Berger HJ, Gottschalk A, Zaret BL: Effect of oral propanolol therapy upon left

ventricular performance in coronary artery disease as assessed by quantitative radionuclide angiocardiography.

45. Berger HJ, Gottschalk A, Zaret BL: Dual radionuclide imaging of myocardial infarction in man:

Discordant size of decreased 201 T1 activity and increased 99mTc-prophosphate uptake. J Nucl Med 18:594, 1977.

46. Berger BJ, Matthay RA, Gottschalk A, Zaret BL: Non-invasive radionuclide assessment of right

ventricular ejection fraction in chronic obstructive pulmonary disease. J Nucl Med 18:601, 1977. Revised 5/13/08 13 Alexander Gottschalk, M.D.

47. Matthay RA, Berger HJ, Loke JS, Gottschalk A, Zaret BL: Effect of animophylline on right and left

ventricular ejection fraction in chronic obstructive pulmonary disease. Am Rev Respir Dis 115-140, 1977.

48. Borkowski H, Berger HJ, Langou RA, Cohen LS, Gottschalk A, Zaret BL: Rapid assessment of left

ventricular performance during exercise induced myocardial ischemia: First pass radionuclide technique. Circulation 56:Suppl. III, III-108, 1977.

49. Reduto LA, Berger HJ, Cohen LS, Gottschalk A, Zaret BL: Sequential radionuclide assessment of left

and right ventricular performance following acute myocardial infarction. Circulation 56:Suppl. III, III-65, 1977.

50. Marshall RC, Berger HJ, Reduto LA, Cohen LS., Gottschalk A, Zaret BL: Effect of oral propanolol

therapy upon left ventricular performance in coronary artery disease: Non-invasive assessment by sequential radionuclide angiocardiography. Circulation 56:Suppl. III, III-32, 1977.

51. Riba AL, Downs J, Gottschalk A, Strauss HW, Andriole VT, Zaret BL: Pyrophosphate radionuclide

imaging of experimental infective endocarditis. Circulation 56:Suppl. III, III-38, 1977.

52. Matthay RA, Berger HJ, Loke J, Dolan TF, Fagenholz, Gottschalk A, Zaret BL: Right and left ventricular performance in cystic fibrosis: Assessment by non-invasive radionuclide angiography. Chest 72:407, 1977.

53. Riba AL, Thakur ML, Downs J, Gottschalk A, Andriole VT, Zaret BL: Detection of experimental

infective endocarditis with Indium-111 labeled platelets. Clin Res 26:264A, 1978.

54. Thakur ML, Gottschalk A, Zaret BL: Indium-111 labeled polymorphonuclear leukocytes in acute myocardial infarction: Influence of infarct age and regional myocardial blood flow upon myocardial imaging and tissue uptake. Clin Res 26:274A, 1978.

55. Alexander J, Dainiak N, Duffy T, Schwartz P, Gottschalk A, Zaret BL: Prospective non-invasive

assessment of Adriamycine-induced cardiac dysfunction using serial radionuclide angiocardiography. Clin Res 26:431A, 1978.

56. Riba AL, Thakur ML, Gottschalk A, Zaret BL: Imaging of acute coronary artery thrombosis with

Indium-111 platelets. Circulation 58(4) Supplement No. 11:II-4, 1978.

57. Reduto LA, Johnston DE, Berger HJ, Gottschalk A, Zaret BL: Radionuclide left ventricular performance and reserve following acute myocardial infarction: Relationship to resting performance in the acute infarct period. Circulation 58(4) Supplement No. 11:II-94, 1978.

58. Goldman L, Feinstein AR, Batsford WP, Cohen LS, Gottschalk A, Zaret BL: Impact of cardiovascular

nuclear medicine on clinical decision making. Circulation 58(4) Supplement No. 11:II-217, 1978.

59. Alexander J, Dainiak N, Berger HJ, Reduto LA, Johnstone DE, Gottschalk A, Zaret BL: Adriamycine cardiotoxicity: Prospective evaluation by serial first-pass radionuclide angiocardiography. Circulation 58(4) Supplement No. 11:II-239, 1978.

60. Riba AL, Thakur ML, Gottschalk A, Andriole VT, Zaret BL: Cellular imaging of experimental

endocarditis. Circulation 58(4) Supplement No. 11:II-508, 1978.


61. Johnstone DE, Sands MJ, Reduto LA, Berger HJ, Wackers FJTh, Cohen LS, Gottschalk A, Zaret BL: Comparison of exercise radionuclide ventricular performance and thallium-201 myocardial perfusion in coronary artery disease. Circulation 58(4) Supplement No. 11:II-511, 1978.

62. Berger HJ, Johnstone DE, Sands MJ, Gottschalk A, Zaret BL: First-pass radionuclide assessment of

right ventricular performance during exercise in coronary artery disease: relationship to left ventricular reserve and right coronary stenosis. Circulation 58(4) Supplement No. 11:II-514, 1978.

63. Berger HJ, Gottschalk A, Zaret BL: First-pass radionuclide angiography for evaluation of right and left

ventricular performance: Computer applications and technical considerations. Nuclear Cardiology: Selected Computer Aspects. Society of Nuclear Medicine, 1978.

64. Berger JH, Reduto LA, Johnstone DE, Borkowski H, Sands JM, Cohen LS, Langou RA, Gottschalk A,

Zaret BL: Global and regional left ventricular response to bicycle exercise in coronary artery disease. Assessment by quantitative radionuclide angiocardiography. Am J Ned 66:13-21, 1979.

65. Goodman MM, Thakur ML, Hoffer PB, Riba AL, Gottschalk A: Indium-111 desferioxamine

complexes: Preparation and stability studies. J Labeled Compounds 16:1, 1979.

66. Thakur ML, Gottschalk A: Role of radiopharmaceuticals in nuclear hematology. Proceedings of the 2nd International Symposium on Radiopharmaceuticals. March 19-22, 1979, Seattle, Washington.

67. Thakur ML, Walsh L, Zaret BL, and Gottschalk A: Effect of membrane active drugs on In-111 labeled

human polymorphonuclear leukocytes (In-PMN). J Nucl Med 21:25, 1980.

68. Davies RA, Thakur ML, Berger HJ, Wackers F, Gottschalk A, Zaret B: In-111 labeled autologous leukocytes (In-COBC) for imaging inflammatory response to acute myocardial infarction (MI) in man. J Nucl Med 21:89, 1980.

69. Thakur ML, Gottschalk A: An interactive radiochemical, facility between the Yale Medical Center and

the Brookhaven National Laboratory. Nuclear Medicine Contractors Meeting, Washington, D.C., 1980.

70. Zoghbi SS, Sostman HD, Neumann RD, Thakur ML, Carbo P, Lord P, Gottschalk A, Greenspan RH:

The influence of heparin on the in vivo distribution of In-111 platelets (In-111-P) in an experimental canine model. J Nucl Med 22:55, 1981.

71. Sostman HD, Neumann RD, Zoghbi SS, Greenspan RH, Gottschalk A: Clinical and experimental

studies of pulmonary embolism using 111Indium labeled platelets. Invest Radiol 16:392, 1981.

72. Zoghbi SS, Thakur ML, Gottschalk A: Investigations into agents for improving cell labeling with positron and gamma emitting radionuclides. J Labeled Comp Radiopharm 1818:280, 1981.

73. Zacharis HM, Thakur ML, Gottschalk A: Radioiodnation of arachidonic acid. Preparation and

evaluation. J Labeled Comp Radiopharm 18:75, 1981.

74. Zoghbi SS, Thakur ML, Gottschalk A, et al: Selective cell labeling: A potential radioactive agent for labeling human neutrophils. J Nucl Med 22:32, 1981.

75. Zoghbi SS, Neumann RD, Gottschalk A: A Simplified Method for Labeling Bioactive Proteins with

Indium-111. Radiology 149(p):243, 1983.


76. Zoghbi SS, Neumann RD, Gottschalk A: Preparation of high specific activity of Indium-111-DTPA labeled antibodies (II). Invest Radiol 19:S32, 1984.

77. Strauss EB, Sostman HD, Gottschalk A: Radiographic infiltrate, matching perfusion defect and normal

ventilation: A sign of pulmonary embolism. Radiology 153:P299, 1984.

78. Zoghbi SS, Neumann RD, Gottschalk A: A practical approach to the preparation of high specific activity Indium-111-DTPA labeled bioactive proteins. J Nucl Med 26:439, 1985.

79. Neumann RD, Kirkwood JM, Zoghbi SS, Ernstoff MS, Cornelius EA, Hoffer PB, Gottschalk A: GA-67

vs IN-111-DTPA-Anti-p97 monoclonal antibody (MoAb) for scintigraphic detection of metastatic melanoma. J Nucl Med 26:P15, 1985.

80. Zoghbi SS, El Rassi Z, Neumann RD, Gottschalk A: Apparent failure of DTPA protein conjugations:

pitfalls and solutions. J Nucl Med 26: P121, 1985.

81. Zoghbi SS, Neumann RD, Gottschalk A: The ultrapurification of IN-111 for radiotracer studies. Invest Radiol 20:S50, 1985.

82. Zoghbi SS, Gottschalk A: The in vivo kinetics of Indium-111 labeled polyclonal anticollagen antibody

(type I) for detection of tissue injury in murine model. Invest Radiol 26:S30, 1986.

83. Zoghbi SS, Gottschalk A: The chronic cannulation of rat jugular vein to insure intravenous injection and to simplify repeated dose delivery or blood withdrawal. Invest Radiol 26:S52, 1986.

84. Neumann RD, Cornelius EA, Zoghbi SS, Kirkwood JM, Ernstoff JS, Hoffer PB, Gottschalk A: Ga-67 vs

In-111-DTPA-Anti-p97 or IN-111-DTPA-Anti-p240 murine MoAbs for scintigraphic detection of metastatic melanoma. J Nucl Med 28(4):P68, 1987.

85. Zoghbi SS, Gottschalk A: Indium-111 labeled monoclonal anti-laminin (Lam-1) antibody: Detection of

basement membrane injury. Invest Radiol 22:S27, 1989.

86. Griffiths D, Hoffer PB, Gottschalk A: TC-99m SbSC lymphoscintigraphy in cutaneous malignant melanoma: Is a 24 hour image necessary? J Nucl Med 29(5):893, 1988.

87. Setaro JF, Koster K, Zubal IG, Gottschalk A, Hoffer PB, Black HR: Captopril renal scintigraphy (CRS)

is effective for diagnosis and prediction of cure in hypertension (HTN) with renal artery stenosis (RAS). Circulation 78(Suppl. II):268, 1988.

88. Chen CC, Hoffer PN, Gottschalk A, Koster K, Setaro JF, Black HR: Captopril renal scintigraphy

parameters for diagnosis of renovascular hypertension. Clin Nucl Med 14:235, 1989.

89. Zoghbi SS, Deveny SM, Smith GJW, Gottschalk A: Indium-111 monoclonal antilaminin AB (Lam-1): An in vivo probe to detect irradiation lung injury. Accepted as poster presentation, SNM Meeting 1989. J Nucl Med 30:916, 1989.

90. Gottschalk A, Stein PD: Lung scan perfusion defects limited to matching pleural effusions indicate a

low probability of pulmonary embolism, but do not confidently exclude the diagnosis. J Nucl Med 32(5):950, 1991.


91. Stein PD, Gottschalk A, Hales CA, Saltzman HA, Vreim CE, Alavi A, Weg JG: Ventilation/perfusion scans in patients with a normal chest radiograph and suspected pulmonary embolism. J Nucl Med 32(5):950-951, 1991.

92. Gottschalk A: The revised PIOPED Diagnostic Criteria in Evaluation of Pulmonary Embolism. The

Nuclear Medicine Quality Assurance Program, Washington D.C., September 1994.

93. Stein PD, Henry JW, Gottschalk A: New Observations on V/Q Scan Diagnosis of PE using Data from the PIOPED study. Presented May 9, 1994, at the Fleischner Society Scientific Meeting in San Miniato, Italy.

94. Ludman CN, Hough DO, Cooper TG, Kasavana H, Gottschalk A: Presented a poster “Meniscal

Appearance in a Cohort of Symptomatic Competitive Gymnasts” at SMR Third Annual Scientific Meeting, August 19-25, 1995, Mice, France.

95. Nordell B, Einarsdottir H, Hoisington L, Cooper T, Gottschalk A: Low dose GD perfusion studies of

kidney with inversion recovery snapshot FLASH. Abstract submitted at the Third Meeting of the Society of Magnetic Resonance in New York the week of April 27 – May 3, 1996.

ORIGINAL ARTICLES 1. Anger HO and Gottschalk A: Detection of brain tumors with the positron scintillation camera. UCRL-

10697, February, 1963. 2. Anger HO and Gottschalk A: Localization of brain tumors with the positron scintillation camera. J Nucl

Med 4:326-330, 1963. 3. Lawrence JH, Tobias CA, Born JL, Gottschalk A, Linfoot J and Kling RP: Alpha particle and proton

beams in therapy. JAMA 186:236-245, 1963. 4. Lawrence JH, Tobias CA, Linfoot JA, Born JL, Gottschalk A, and Kling RP: Heavy particles, the

Bragg curve and suppression of pituitary function in diabetic retinopathy. Diabetes 12:490-501, 1963. 5. Gottschalk A, Lyman JT, and McDonald LW: The use of the Bragg Peak for brain-tumor therapy.

UCRL-11184, Fall, 1963. 6. Gottschalk A and Anger HO: The sensitivity of the positron scintillation camera for detecting simulated

brain tumors. AM J Roentgen 92:174-176, 1964. 7. D’Angio GJ, Gottschalk A, and Lyman JT: Bone growth disturbance as an index for RBE

investigations – preliminary observations. Donner Laboratory Semiannual report, UCRL-11387, Spring, 1964.

8. D’Angio GJ, Lawrence JH, Gottschalk A, and Lyman JT: The relative efficiency of high LET

radiations (Bragg peak lithium ions) on normal rabbit skin using integral dose as a basis for comparison. Donner Laboratory Semiannual report, UCRL-11387, Spring, 1964. Also published in Nature 204:1276-1268, 26, 1964.

9. Lawrence JH, Tobias CA, Born JL, Linfoot JA, Kling RP, and Gottschalk A: Alpha and proton heavy

particles and the Bragg peak in therapy. Trans Amer Clin Clinatological Assoc 75:111-115, 1964.


10. Gottschalk A and Anger HO: Letter to the Editor, J Nucl Med 5:569, 1964. 11. Anger HO, VanDyke DC, Gottschalk A, Yano Y, and Schaer LR: The scintillation camera in diagnosis

and research. Nucleonics, January, 1965. 12. Hazel JJ, McDonald LW, and Gottschalk A: A preliminary curve relating dose in time to pituitary

histologic changes following 910 MeV alpha particle irradiation. Donner Laboratory Semiannual report UCRL – pp 58-65, Spring, 1965.

13. Gottschalk A, McCormack KR, Adams JE, and Anger HO: A comparison of results of brain scanning

using gallium-68 EDTA and the positron scintillation camera, with mercury-203-neohydrin and the conventional focused collimator scanner. Radiology 84:502-506, 1965.

14. Gottschalk A and Anger HO: Use of the scintillation camera to reduce radioisotope scanning time.

JAMA 192:448-452, 1965. 15. Gottschalk A and Anger HO: Renal scintigraphy with the gamma-ray scintillation camera and HG-203-

neohydrin. Radiology 84:861-867, 1965. 16. Gottschalk A: The technique of patient alignment for pituitary irradiation with high energy MeV alpha

particles. Donner Laboratory Semiannual Report, UCRL-16246 pp 66-73, 1965. 17. Harper PV, Lathrop KA, Jiminez F, Fink R, and Gottschalk A: Technetium-99m as a scanning agent.

Radiology 85:101-108, 1965. 18. Sparberg MD, Gottschalk A, and Kirsner JB: Liver abscess complicating regional enteritis. Report of

two cases. Gastroenterol 49:548-551, 1965. 19. Gottschalk A: Report on the use of the scintillation camera. Proc. First Conf. Report: The scintillation

Camera, August, 1965. 20. Gottschalk A: The use of short-lived isotopes and rapid imaging devices in Nuclear Medicine. Weiss

Memorial Hospital Bulletin, pp 4-12, Spring, 1966. 21. Petasnick JP and Gottschalk A: Spleen scanning with technetium-99m sulfur colloid and the

scintillation camera. J Nucl Med 7:733-739, 1966. 22. Gottschalk A: Technical advances in pediatric diagnosis and therapy: Radioisotopes Proc. Symposium

Tumors of Infancy and Childhood. 1:A73-A81, University of Minnesota. 23. Gottschalk A: Radioisotope scintiphotography with technetium-99m and the gamma scintillation

camera. Am J Roentgen 97:860-868, 1966. 24. Gottschalk A, Harper PV, Jiminez FF, and Petasnick JP: Qualification of the respiratory motion artifact

in radioisotope scanning with the rectilinear focused collimator scanner and the gamma scintillation camera. J Nucl Med 7:243-251, 1966.

25. Schaer LR, Anger HO, and Gottschalk A: Gallium edetate 68GA experiences in brain-lesion detection

with the positron camera. JAMA 198:811-813, 1966. 26. Gottschalk A: Liver scanning. JAMA 200:630-633, 1967. Revised 5/13/08 18 Alexander Gottschalk, M.D.

27. Gottschalk A: Renal scanning. JAMA 202:221-224, 1967. 28. Forland M, Gottschalk A, Spargo BH, and Grossman BJ: Renal localization for percutaneous biopsy by

scanning with technetium-99m iron complex. Pediatrics 39:872-875, 1967. 29. Gottschalk A, Jiminez FF, Lu Chein-Tai, Beck RN, and Harper PV: Imaging technetium-99m

compounds with the gamma scintillation camera, and the use of this system to avoid the distortion of respiratory motion in radioisotope scintiphotography. Radioaktive isotope in Klinik und Forschung, Vol. 7, Editors K Fellinger and R Hofer. Van Urban & Schwarzenberg, Muchen, 1967, pp 94-102.

30. Hoffer PB, Jones WB, Crawford RB, Beck RN, and Gottschalk A: Fluorescent thyroid scanning? A

new method of imaging the thyroid. Radiology 90:342-344, 1968. 31. Hoffer PB, Charleston DB, Beck RN, and Gottschalk A: Fluorescent thyroid scanning without the use

of radioactive nuclides in vivo. J Nucl Med 9:324, 1968. 32. Polcyn RE, Paloyan D, Hendricks KO, Gottschalk A, and Harper PV: Use of a 1600 channel analyzer

with a gamma scintillation camera in the quantitative assessment of organ function. Proc. Symposium on radioactive isotopes in clinical medicine and research. Bad Gastein, Austria, January, 1968. Published in Radioaktive Isotope in Klinik und Forschung, Vol VIII. Editors, K Fellinger and R Hoffer. Urban & Schwarzenberg, Munchen, 1968, pp 11-22.

33. Gottschalk A, Abatie JD, Petasnick JP, Polcyn RE, Beck RN, and Charleston DB: The comparison

between sensitivity and resolution based on a clinical evaluation with the ACRH brain scanner. Proc. Symposium on Medical Radioisotope Scintigraphy, Vol II, Salzburg, Austria, August, 1968. International Atomic Energy Agency, Vienna, pp 261-271, 1969.

34. Hoffer PB, Charleston DB, Beck RN, and Gottschalk A: Fluorescent scanning: A new investigative

technique. Proc. Symposium on Medical Radioisotope Scintigraphy, Vol I Salzburg, Austria, August, 1968. International Atomic Energy Agency, Vienna, pp 261-271, 1969.

35. DeGowin RL, Sorenson LB, Charleston DB, Gottschalk A, and Greenwald JH: Retention of radioiron

in the lungs of a woman with idiopathic pulmonary hemosiderosis. Ann Int Med 69:1213-1220, 1968. 36. Polcyn RE and Gottschalk A: Dynamic studies with the newer instrumentation. Symposium on

Nuclear Medicine and Therapeutic Radiology. The Radiologic Clinics of North America. Vol. II, No. 2, Ed., E. Richard King, W.B. Saunders Company, Philadelphia, August 1969, pp.243-255.

37. Hoffer PB, Polcyn RE, Moody R, Lowe HJ, and Gottschalk, A: Fluorescence detection: Application to

the study of cerebral blood flow. J. Nucl Med 10:651-653, 1969. 38. DeGowin RL, Lavender AR, Forland A, Charleston DB, and Gottschalk A: Erythropoiesis and

erythropoietin in patients with chronic renal failure treated with hemodialysis and testosterone. Ann Int Med 72(6):913-918, 1970.

39. Baron JM, Kingdon HS, Block GE, and Gottschalk A: Splenectomy in a hemophiliac. Diagnosis of

occult rupture preoperative evaluation and postoperative support. Surg Clin North Am 50(1):205-211, 1970.

40. Kranzler JK, Vollert JM, Harper PV, Polcyn RE, Strauss FH, and Gottschalk A: The diagnostic value

of hepatic pliability as assessed from inspiration and expiration views on the gamma camera. Radiology 97(2):323-326, 1970.


41. Hoffer PB, Beck RN, Lembares N, Charleston DB, and Gottschalk A: Use of lithium drifted

germanium detectors for clinical radionuclide scanning. J Nucl Med 12(1):25-27, 1971. 42. Moody RA, Hoffer PB, Polcyn RE, Lowe HJ, Gottschalk A, and Dobben GD: K-shell fluorescence for

the study of regional cerebral blood flow. J Neurosurg 35(2):181-184, 1971. 43. Pinsky SM, Hoffer PB, Flom R, Quinn JL, and Gottschalk A: Correlation between brain tumor

detectability on brain scan and protein levels for spinal fluid. Radiology 98(3):672-673, 1971. 44. Gottschalk A, Usher MS, Turner DA, Polcyn RE, and Quinn JL: The scintillation camera with divering

collimator. Physical parameters, and a clinical evaluation. Semin Nucl Med 1(2), Radionuclide Studies of the Lung, April, 1971.

45. Hoffer PB, and Gottschalk A: Fluorescent thyroid scanning: Scanning without radioisotopes. Initial

clinical results. Radiology 99(1):117-123, 1971. 46. Heck LL, and Gottschalk A: The appearance of intrahepatic biliary duct dilation on the liver scan.

Radiology 99(1):135-140, 1971. 47. Gottschalk A: Brain scanning – It is becoming unnecessarily complicated? Am. J Roent Radiol Ther

Nucl Med CXI (4):851-852, 1971. 48. Bekerman C, and Gottschalk A: The diagnostic significance of the relative uptake of liver versus spleen

in technetium-99m sulfur colloid scintiphotography. J Nucl Med 12(5):237-240, 1971. 49. Ghahremani GG, and Gottschalk A: New normal values for thyroid uptake of radioactive iodine.

JAMA 217:337-339, 1971. 50. Evens R, Gottschalk A, Maynard CD, Saunders TP, and Bennett LR: Nuclear Medicine training in

medical schools. J Nucl Med 12(8):574, 1971. 51. Hoffer PB, Bernstein J, and Gottschalk A: Fluorescent techniques in thyroid imaging. Semin Nucl Med

1(3):379-389, No.3 – Diagnostic Radionuclide Studies of Thyroid, July, 1971. 52. Heck LL, and Gottschalk A: Use of the pinhole collimator for imaging the posterior fossa on brain

scans. Radiology 101(2):443-444, 1971. 53. Beierwaltes WH, Bennett LR, Burrows BA, Gottschalk A, Harris CC, Saenger EL, Tauxe WN, and

Kuhl DE: (Chairman). Society of Nuclear Medicine Committee on Education. Components of professional competence of physicians in Nuclear Medicine. J Nucl Med 12(12):840-841, 1971.

54. Landman S, Polcyn RE, and Gottschalk A: Pancreas imaging – is it worth it? Radiology 100:631-636,

1971. 55. McAfee JG, Bilbao MK, Donner MW, Gottschalk A, Greenspan R, Kundel HL, Mellins HZ, Taplin

GV, Ter-Pogossian MM, Webster EW, Whitehouse WM, Young LW: Research Training in Radiology. Report of the Radiology Training Committee, National Institutes of Health, Bethesda, Maryland, DHEW Publications No. (NIH) 72-222, June, 1971.

56. Heck LL, Hoffer PB, and Gottschalk A: Brain scanning – successes, limitations, and future

developments. Clin Neurosurg 18:371-386, 1971. Revised 5/13/08 20 Alexander Gottschalk, M.D.

57. Turner DA, Pinsky SM, Gottschalk A, Hoffer PB, Ultmann JE, and Harper PB: The use of 67-Gallium

scanning in the staging of Hodgkin’s disease. Radiology 104:97-101, 1972. 58. Turner DA, Gottschalk A, Hoffer PB, Ultmann JE, and Harper PV: 67Ga scanning in the staging of

malignant lymphoma: Successes and failures. J Nucl Med 13(6):474, 1972. 59. Moody RA, Olsen JO, Gottschalk A, and Hoffer PB: Scanning of the posterior fossa. J Neurosurg

36(2):148-152, 1972. 60. Tully RJ, Stark VJ, Hoffer PB, and Gottschalk A: Renal scan prior to biopsy – a method of renal

localization. J Nucl Med 13(7):544-547, 1972. 61. Oppenheim BE, Hoffer PB, and Gottschalk A: The use of inspiration-expiration scintiphotographs to

determine the intrinsic nature of liver defects. J Nucl Med 13(7):554, 1972. 62. Hoffer PB, Gottschalk A, and Refetoff S: Thyroid scanning techniques. The old and the new. Current

Problems in Radiology, Editorial Board, Robert D. Moseley, Jr., D.H. Baker, R.O. Gorson, M.S, Anthony Lalli, Howard B. Latourette, J.L. Quinn, Year Book Medical Publishers, Inc., Chicago, Illinois, January-February, 1972.

63. Tetalman MR, Hoffer PB, Heck LL, Kunzmann A, and Gottschalk A: Perfusion lung scan in normal

volunteers. Radiology 106(3):593-594, 1973. 64. Harper PV, Schwartz J, Beck RN, Lathrop KA, Lembares N, Krizek H, Gloria I, Dinwoodie R,

McLaughlin A, Stark VJ, Bekerman C, Hoffer PB, Gottschalk A, Resnekov L, Al-Sakir J, Mayorga A, and Brooks HL: Clinical myocardial imaging with nitrogen-13 ammonia. J Nucl Med 108:613-618, 1973.

65. Hoffer PB, Turner D, Gottschalk A, Harper PB, and Ultmann JE: Whole-body radiogallium scanning

for staging of Hodgkin’s disease and other lymphomas. International Symposium of Hodgkin’s Disease, National Cancer Institute Monograph 36, January, 1973, NIH Publication No. 73-378, U.S> Department of Health, Education, and Welfare, Public Health Service, NIH.

66. Turner DA, Gottschalk A, Hoffer PB, Harper PV, Moran E, and Ultmann JE: Gallium-67 scanning in

the staging of Hodgkin’s Disease. Medical Radioisotope Scintigraphy 1972, Vol. II, IAEA, pp. 615-630, Vienna, 1973.

67. Hoffer PB, and Gottschalk A: Tumor scanning agents. Semin Nucl Med 4(3):305-316, 1974. 68. Turner DA, Gottschalk A, and Hoffer PB: Critical Review (on the article, Interpretation of 67Ga

Photoscan, by SM Larson, MS Miler, GS Johnston, published in J Nucl Med 14:208, 1973/Invest Rad 9(4):288, 1974.

69. Chiles JT, Mintzer RA, Hoffer PB, Gottschalk A: Splenic mobility and its effect on estimates on

splenic mass. Radiology 114:407-410, 1975. 70. Oppenheim BE, Hoffer PB, Gottschalk A: Nuclear imaging: A new dimension. Radiology 118:491-

494, 1976. 71. Mall JC, Bekerman C, Hoffer PB, and Gottschalk A: A unified radiological approach to the detection

of skeletal metastases. Radiology 118:323-328, 1976. Revised 5/13/08 21 Alexander Gottschalk, M.D.

72. Caride VJ, Puri S, Slavin JD, Lange RC, and Gottschalk A: The usefulness of the posterior oblique

views in perfusion lung imaging. Radiology 121:669-671, 1976. 73. Taylor KJW, Sullivan D, Rosenfield AT, and Gottschalk A: Grey-scale ultrasound and isotope

scanning: Complementary techniques for imaging the liver. Am J Roentgenol 128:277-281, 1977. 74. Marshall RC, Berger HJ, Costin JC, Freedman GS, Wolberg J, Cohen LS, Gottschalk A, Zaret BL:

Assessment of cardiac performance with quantitative radionuclide angiocardiography: Sequential left ventricular ejection fraction, normalized left ventricular ejection rate, and regional wall motion. Circulation 56(5):820-829, 1977.

75. Caride VJ, Taylor KJW, Cramer JA, and Gottschalk A: Evaluation of liposomes (99mTc-DTPA) in

mice. J Nucl Med 18:1067, 1977. 76. Bekerman C, Moran EM, Hoffer PB, Hendrix RW, Gottschalk A: Scintigraphic evaluation of

lymphoma: A comparative study of 67Ga-citrate and 111In-bleomycin. Radiology 123:687-694, 1977. 77. Caride VJ, and Gottschalk A: Recent advances in cancer diagnosis with nuclear medicine techniques.

Cancer 40:495-499, 1977. 78. Berger HJ, Gottschalk A, Zaret BL: Dual radionuclide study of myocardial infarction: Comparison of

thallium-201 and technetium-99m stannous pyrophosphate imaging in man. Ann Int Med 88:1450154, 1978.

79. Zakireh B, Thakur ML, Maleeh HL, Gottschalk A, Root RK: Chemotaxis and random migration of In-

111 labeled neutrophils. Clin Research 26:459, 1978. 80. Marshall RC, Berger HJ, Reduto LA, Gottschalk A, Zaret BL: Variability in sequential measures of left

ventricular performance assessed by radionuclide angiocardiography. Am J Cardiol 41:531-536, 1978. 81. Berger HJ, Matthay RA, Loke J, Marshall RC, Gottschalk A, and Zaret BL: Assessment of cardiac

performance with quantitative radionuclide angiocardiography: Right ventricular ejection fraction with reference to findings in chronic obstructive pulmonary disease. Am J Cardiol 41(5):897-905, 1978.

82. Makhija MC, Bronfman HJ, Lange RC, Glenn WL, Gottschalk A: Ventilation patterns mimicking

COPD in patients with diaphragm pacing for Ondine’s curse. Radiology 129:111-116, 1978. 83. Hauser MF, Gottschalk A: Comparison of the Anger tomographic scanner and the 15 inch scintillation

camera for gallium imaging. J Nucl Med 19:1074-1077, 1978. 84. Itzchak Y, Glickman MG, Gottschalk A, Lange R, Downing SE: Hemodynamic and morphologic

evaluation of the spleen after splenic vein ligation in the dog. Invest Radiol 13:155-160, 1978. 85. Marshall RC, Berger HJ, Reduto LA, Cohen LS, Gottschalk A, Zaret BL: Assessment of cardiac

performance with quantitative radionuclide angiocardiography: Effects of oral propranolol on global and regional left ventricular function in coronary artery disease. Circulation 58(5):808-814, 1978.

86. Reduto LA, Berger HJ, Geha A, Hammond G, Cohen LS, Gottschalk A, Zaret BL: Radionuclide

assessment of ventricular performance during propranolol withdrawal prior to aortocoronary bypass surgery. Am Heart J 96:714-722, 1978.


87. Riba A, Downs J, Thakur ML, Gottschalk A, Andriole VT, Zaret BL: Technetium-99m stannous pyrophosphate imaging of infective endocarditis. Circulation 58(1):111-119, 1978.

88. Reduto LA, Berger HJ, Cohen LS, Gottschalk A, Zaret BL: Sequential radionuclide assessment of left

and right ventricular performance following acute transmural myocardial infarction. Ann Int Med 89(4):441-447, 1978.

89. Thakur ML, Gottschalk A, Zaret BL: Imaging experimental myocardial infarction with In-111 labeled

autologous leukocytes. Effects of infarct age and residual regional myocardial blood flow. Circulation 60:297-305, 1978.

90. Sullivan DC, Taylor KJW, Gottschalk A: The use of ultrasound to enhance the diagnostic utility of the

equivocal liver scintigraphy. Radiology 128:727-733, 1978. 91. Matthay RA, Berger HJ, Loke J, Gottschalk A, Zaret BL: Effects of aminophylline upon right and left

ventricular performance in chronic obstructive pulmonary disease. Am J Med 65:903-910, 1978. 92. Riba AL, Thakur ML, Gottschalk A, Zaret BL: Cellular imaging of experimental endocarditis.

Circulation 57/58, Suppl II, 131, 1978. 93. Riba AL, Thakur ML, Gottschalk A, Andriole VT, Zaret BL: Imaging experimental infective

endocarditis with Indium-111 labeled blood cellular components. Circulation 59:336-343, 1979. 94. Alexander J, Dainiak N, Berger HJ, Goldman L, Johnstone D, Reduto L, Duffy T, Schwartz P,

Gottschalk A, Zaret BL. Serial assessment of doxorubicin cardiotoxicity with quantitative radionuclide angiocardiography. New England Journal of Medicine. 300(6):278-83, Feb 1979.

95. Berger HJ, Reduto LA, Johnstone DE, Borkowski H, Sands JM, Cohen LS, Langou RA, Gottschalk A,

Zaret BL, Pytlik L. Global and regional left ventricular response to bicycle exercise in coronary artery disease. Assessment by quantitative radionuclide angiocardiography. American Journal of Medicine. 66(1): 13-21, Jan 1979.

96. Espinola LG, Beaucaire J, Gottschalk A, Caride VJ. Radiolabeled liposomes as metabolic and scanning

tracers in mice. II. In-111 oxine compared with Tc-99m DTPA, entrapped in multilamellar lipid vesicles. Journal of Nuclear Medicine. 20(5): 434-40, May 1979.

97. Alderson PO, Gottschalk A. Letter to the editors--ventilation-perfusion studies for pulmonary

embolism: a rebuttal to Dr. Eugene Robin. Seminars in Nuclear Medicine. 9(2): 145-6, Apr 1979. 98. Wackers FJ, Berger HJ, Johnstone DE, Goldman L, Reduto LA, Langou RA, Gottschalk A, Zaret BL.

Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: validation of the technique and assessment of variability. American Journal of Cardiology. 43(6): 1159-66, Jun 1979.

99. Armas R, Thakur ML, Gottschalk A. A simple method of spleen imaging with 99mTc-labeled

erythrocytes. Radiology. 132(1): 215-6, Jul 1979. 100. Zakhireh B, Thakur ML, Malech HL, Cohen MS, Gottschalk A, Root RK. Indium-111-labeled human

polymorphonuclear leukocytes: viability, random migration, chemotaxis, bacterial capacity, and ultrastructure. Journal of Nuclear Medicine. 20(7): 741-7, Jul 1979.

101. Johnstone DE, Wackers FJTh, Berger HJ, Kelley MJ, Gottschalk A, and Zaret BL: Effect of patient

positioning on left lateral thallium-201 myocardial images. J Nucl Med 20:183-188, 1979. Revised 5/13/08 23 Alexander Gottschalk, M.D.

102. Thakur ML, Gottschalk A, Zaret BL. Imaging experimental myocardial infarction with indium 111-

labeled autologous leukocytes: effects of infarct age and residual regional myocardial blood flow. Circulation. 60(2): 297-305, Aug 1979.

103. Berger HJ, Matthay RA, Pytlik LM, Gottschalk A, Zaret BL. First-pass radionuclide assessment of

right and left ventricular performance in patients with cardiac and pulmonary disease. Seminars in Nuclear Medicine. 9(4): 275-95, Oct 1979.

104. Riba AL, Thakur ML, Gottschalk A, Zaret BL. Imaging experimental coronary artery thrombosis with

indium-111 platelets. Circulation. 60(4): 767-75, Oct 1979. 105. Berger HJ, Johnstone DE, Sands JM, Gottschalk A, Zaret BL. Response of right ventricular ejection

fraction to upright bicycle exercise in coronary artery disease. Circulation. 60(6): 1292-300, Dec 1979. 106. Berger HJ, Matthay RA, Davies RA, Zaret BL, Gottschalk A. 1979 Memorial Award Paper.

Comparison of exercise right ventricular performance in chronic obstructive pulmonary disease and coronary artery disease: noninvasive assessment by quantitative radionuclide angiocardiography. Investigative Radiology. 14(5): 342-53, 1979.

107. Neumann RD, Gottschalk A: Diagnostic techniques in nuclear medicine. Ann Rev Nucl Part Sci

29:283-312, 1979. 108. Matthay RA, Berger HJ, Davies RA, Loke J, Zaret BL, Gottschalk A. Effect of steady state exercise on

right and left ventricular performance in chronic obstructive pulmonary disease. Noninvasive assessment by radionuclide angiocardiography. Chest. 77(2 Suppl): 303, Feb 1980.

109. Matthay RA, Berger HJ, Loke J, Dolan TF, Fagenholz SA, Gottschalk A, Zaret BL. Right and left

ventricular performance in ambulatory young adults with cystic fibrosis. British Heart Journal. 43(4): 474-80, Apr 1980.

110. Matthay RA, Berger HJ, Loke J, Dolan TF, Fagenholz SA, Gottschalk A, Zaret BL: Right and left

ventricular performance in ambulatory young adults with cystic fibrosis. Br Heart J 43:474-480, 1980. 111. Reduto LA, Berger HJ, Johnstone DE, Hellenbrand W, Wackers FJ, Whittemore R, Cohen LS,

Gottschalk A, Zaret BL. Radionuclide assessment of right and left ventricular exercise reserve after total correction of tetralogy of Fallot. American Journal of Cardiology. 45(5): 1013-8, May 1980.

112. Armas RR, Thakur ML, Gottschalk A. A simplified method of selective spleen scintigraphy with Tc-

99m-labeled erythrocytes: clinical applications. Concise communication. Journal of Nuclear Medicine. 21(5): 413-6, May 1980.

113. Johnstone DE, Sands MJ, Berger HJ, Reduto LA, Lachman AS, Wackers FJ, Cohen LS, Gottschalk A,

Zaret BL. Comparison of exercise radionuclide angiocardiography and thallium-201 myocardial perfusion imaging in coronary artery disease. American Journal of Cardiology. 45(6): 1113-9, Jun 1980.

114. Sullivan DC, Rosenfield NS, Ogden J, Gottschalk A. Problems in the scintigraphic detection of

osteomyelitis in children. Radiology. 135(3): 731-6, Jun 1980. 115. Thakur ML, Riba AL, Gottschalk A, Zaret BL. Canine and rabbit platelets labeled with In-111 oxine

[letter]. Journal of Nuclear Medicine. 21(6): 597-8, Jun 1980. Revised 5/13/08 24 Alexander Gottschalk, M.D.

116. Neumann RD, Sostman HD, Gottschalk A. Current status of ventilation-perfusion imaging. Seminars in

Nuclear Medicine. 10(3):198-217, Jul 1980. 117. Matthay RA, Berger HJ, Davies RA, Loke J, Mahler DA, Gottschalk A, Zaret BL. Right and left

ventricular exercise performance in chronic obstructive pulmonary disease: radionuclide assessment. Annals of Internal Medicine. 93(2): 234-9, Aug 1980.

118. Goldman L, Feinstein AR, Batsford WP, Cohen LS, Gottschalk A, Zaret BL. Ordering patterns and

clinical impact of cardiovascular nuclear medicine procedures. Circulation. 62(4): 680-7, Oct 1980. 119. Berger HJ, Gottschalk A, Zaret BL. Radionuclide assessment of left and right ventricular performance.

Radiologic Clinics of North America. 18(3): 441-66, Dec 1980. 120. Gottschalk A, Armas R, and Thakur ML: Reply (to Som’s letter “Spleen scanning with Tc-99m labeled

red blood cells (RBC)”). Nucl Med 21(10):1000-1001, 1980. 121. Zaret BL, Davies RE, Thakur ML, Berger HJ, Wackers FJ, Gottschalk A: Imaging the inflammatory

response to acute myocardial infartion using Indium-111 labeled autologous leukocytes. Circulation 63:826-832, 1981.

122. Berger H, Sands MJ, Davies R, Wackers FJTh, Alexander J, Lachman A, Williams B, Gottschalk A,

Zaret BL: Exercise left ventricular performance in patients with chest pain, ischemic-appearing exercise electrocardiograms, and angiographically normal coronary arteries. Ann Int Med 94:186-191, 1981.

123. Berger HJ, Davies RA, Batsford WP, Hoffer PB, Gottschalk A, Zaret BL. Beat-to-beat left ventricular

performance assessed from the equilibrium cardiac blood pool using a computerized nuclear probe. Circulation. 63(1): 133-42, Jan 1981.

124. Hoffer PB, Berger HJ, Steidley J, Brendel AF, Gottschalk A, Zaret BL. A miniature cadmium telluride

detector module for continuous monitoring of left-ventricular function. Radiology. 138(2): 477-81, Feb 1981.

125. Zeman RK, Gottschalk A. Current aspects of nuclear imaging in clinical oncology. Cancer. 47(5

Suppl): 1154-8, Mar 1981. 126. Davies RA, Thakur ML, Berger HJ, Wackers FJ, Gottschalk A, Zaret BL. Imaging the inflammatory

response to acute myocardial infarction in man using indium-111-labeled autologous platelets. Circulation. 63(4): 826-32, Apr 1981.

127. Thakur ML, Walsh L, Malech HL, Gottschalk A. Indium-111-labeled human platelets: improved

method, efficacy, and evaluation. Journal of Nuclear Medicine. 22(4): 381-5, Apr 1981. 128. Sostman HD, Brown M, Toole A, Bobrow S, Gottschalk A. Perfusion scan in pulmonary

vascular/lymphangitic carcinomatosis: the segmental contour pattern. Ajr. American Journal of Roentgenology. 137(5): 1072-4, Nov 1981.

129. Simon TR, Neuman RL, Gorelick F, Riely C, Hoffer P, and Gottschalk A: Scintigraphic diagnosis of

cirrhosis: A receiver operator characteristic analysis of the common interpretative criteria. Radiology 138(3):723-726, 1981.


130. Davies RA, Thakur ML, Berger HJ, Wackers FJTh, Gottschalk A, and Zaret BL: Imaging the inflammatory response to acute myocardial infarction in man using Indium-111-labeled autologous leukocytes. Circulation 63(4):826-832, 1981.

131. Davies RA, Laks H, Wackers FJ, Berger HJ, Williams B, Hammond GL, Geha AS, Gottschalk A, Zaret

BL. Radionuclide assessment of left ventricular function in patients requiring intraoperative balloon pump assistance. Annals of Thoracic Surgery. 33(2): 123-31, Feb 1982.

132. Davies RA, Laks H, Berger JH, Wackers FJ, Williams B, Hammond GL, Geha AS, Gottschalk A, and

Zaret BL: Radionuclide assessment of left ventricular function and perfusion in patients requiring intraaortic balloon pump assistance. Ann Thoracic Surg 33:123-131, 1982.

133. Thakur ML, Walsh LJ, Zaret BL, Gottschalk A. Effect of antiarrhythmic drugs on In-111-labeled

leukocytes: chemotaxis and adherence to nylon wool. Journal of Nuclear Medicine. 23(2): 131-5, Feb 1982.

134. Sostman HD, Gottschalk A. The stripe sign: a new sign for diagnosis of nonembolic defects on

pulmonary perfusion scintigraphy. Radiology. 142(3): 737-41, Mar 1982. 135. Sostman HD, Neumann RD, Zoghbi SS, Lord PF, Thakur ML, Carbo P, Greenspan RH, and Gottschalk

A: Experimental studies with 111Indium labeled platelets in pulmonary embolism. Invest Radiol Vol. 17 No. 4:367-374, 1982.

136. Newman GE, Sullivan DC, Gottschalk A, Putman CE. Scintigraphic perfusion patterns in patients with

diffuse lung disease. Radiology. 143(1): 227-31, Apr 1982. 137. Sostman HD, Neumann RD, Loke J, Zoghbi SS, Thakur ML, Greenspan RH, Gottschalk A. Detection

of pulmonary embolism in man with 111In-labeled autologous platelets. Am J Roentgen. American Journal of Roentgenology. 138(5): 945-7, May 1982.

138. Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P. Tomographic

gallium-67 citrate scanning: useful new surveillance for metastatic melanoma. Annals of Internal Medicine. 97(5): 694-9, Nov 1982.

139. Matthay RA, Berger HJ, Davies R, Loke J, Gottschalk A, Zaret BL. Improvement in cardiac

performance by oral long-acting theophylline in chronic obstructive pulmonary disease. American Heart Journal. 104(5 Pt 1): 1022-6, Nov 1982.

140. Sostman HD, Neumann RD, Zoghbi SS, Lord PF, Thakur ML, Carbo P, Greenspan RH, Gottschalk A.

1982 George Simon Memorial Fellowship Award. Experimental studies with 111Indium-labeled platelets in pulmonary embolism. Investigative Radiology. 17(4):367-74, 1982.

141. Berger RB, Zeman RK, Gottschalk A. The technetium-99m-sulfur colloid angiogram in suspected

gastrointestinal bleeding. Radiology. 147(2): 555-8, May 1983. 142. Kirkwood JM, Myers JE, Vlock DR, Neumann R, Ariyan S, Gottschalk A, Hoffer P. Tomographic

gallium-67 citrate scanning. Useful new surveillance for metastatic melanoma. Annals of Surgery. 198(1): 102-7, Jul 1983.

143. Choi BW, Berger HJ, Schwartz PE, Alexander J, Wackers FJ, Gottschalk A, Zaret BL. Serial

radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. American Heart Journal. 106(4 Pt 1):638-43, Oct 1983.


144. Sostman HD, Rapaport S, Glickman MG, Gottschalk A. Problems in noninvasive imaging of

pulmonary embolism. Radiologic Clinics of North America. 21(4): 759-74, Dec 1983. 145. Sostman HD, Zoghbi SS, Smith GJ, Carbo P, Neumann RD, Gottschalk A, Greenspan RH. Platelet

kinetics and biodistribution in canine endotoxemia. Investigative Radiology. 18(5): 425-35, 1983. 146. Sostman HD, Neumann RD, Gottschalk A, Greenspan RH: Perfusion of nonventilated lung on

ventilation-perfusion scintigraphy. Am J. Roentgen 141:151-156, 1983. 147. Alderson PO, Biello DR, Gottschalk A, Hoffer PB, Kroop SA, Lee ME, Ramanna L, Siegel BA,

Waxman AD. Tc-99m-DTPA aerosol and radioactive gases compared as adjuncts to perfusion scintigraphy in patients with suspected pulmonary embolism. Radiology. 153(2): 515-21, Nov 1984.

148. Zoghbi SS, Neumann RD, Gottschalk A. A modified procedure for rapid labelling of low

concentrations of bioactive proteins with indium-111. International Journal of Nuclear Medicine and Biology. 12(3): 159-66, 1985.

149. Zoghbi SS, Thakur ML, Sostman HD, Neumann RD, Carbo P, Lord P, Greenspan RH, Gottschalk A.

The influence of heparin on the in vivo distribution of IN-111 labeled platelets. Investigative Radiology. 20(2): 198-202, 1985.

150. Sostman HD, Rapoport S, Gottschalk A, Greenspan RH. Imaging of pulmonary embolism.

Investigative Radiology. 21(6): 443-54, Jun 1986. 151. Ockleford PA, Coates G, Sostman HD, Gottschalk A. Pulmonary angiography, ventilation lung

scanning, and venography for clinically suspected pulmonary embolism with abnormal perfusion lung scan. Investigative Radiology. 21(8): 678-82, Aug 1986.

152. Zoghbi SS, Neumann RD, Gottschalk A. The ultrapurification of indium-111 for radiotracer studies.

Investigative Radiology. 21(9):710-3, Sep 1986. 153. Zoghbi SS, Neumann RD, Gottschalk A. Preparation and immunoreactivity of high specific activity

indium-111-DTPA labeled monoclonal antibody (MoAb) using ultrapure indium-111. Investigative Radiology. 21(10): 788-92, Oct 1986.

154. Sostman HD, Gottschalk A: Critical Review (on the article, Pulmonary angiography, ventilation lung

scanning, and venography for clinically suspected pulmonary embolism with abnormal perfusion lung scan) by Russell D, Hull MB, et al, published in Ann Intern Med 98:891-899, 1983/Invest Radiol 21:678-682, 1986.

155. Zoghbi SS, el Rassi Z, Neumann RD, Gottschalk A. Quality control and the preparative purification of

low antibody concentrations for radiolabelling using bifunctional chelates. International Journal of Radiation Applications and Instrumentation. Part B, Nuclear Medicine and Biology. 14(5): 529-32, 1987.

156. Strauss EB, Sostman HD, Gottschalk A. Radiographic parenchymal opacity, matching perfusion defect,

and normal ventilation: a sign of pulmonary embolism? Work in progress. Radiology. 163(2): 505-6, May 1987.

157. Warshauer D, Scott G, Gottschalk A. Focal acute acalculous cholecystitis. Ajr. American Journal of

Roentgenology. 149(3): 505-6, Sep 1987. Revised 5/13/08 27 Alexander Gottschalk, M.D.

158. Freimanis R, Zoghbi SS, Gottschalk A. The effect of 'irrelevant' IgG protein selection on target uptake

ratios of radiolabeled antibodies. Investigative Radiology. 23(7): 537-9, Jul 1988. 159. Zoghbi SS, Sostman HD, Duberg AC, Lwebuga-Mukasa J, Carbo PL, Gottschalk A. Radiolabeled

fibronectin for the scintigraphic detection of pulmonary emboli in dogs. Investigative Radiology. 23(8): 574-8, Aug 1988.

160. Zoghbi SS, Thakur ML, Sostman HD, Greenspan RH, Gottschalk A. Indium-111-oxinate labeled swine

platelets and their survival in vivo. Laboratory Animal Science. 38(4): 444-7, Aug 1988. 161. Gottschalk A, Hoffer PB. Positron emission tomography in aging and dementia: effect of cerebral

atrophy. Investigative Radiology. 23(11): 879-80, Nov 1988. 162. Chen CC, Hoffer PB, Vahjen G, Gottschalk A, Koster K, Zubal IG, Setaro JF, Roer DA, Black HR.

Patients at high risk for renal artery stenosis: a simple method of renal scintigraphic analysis with Tc-99m DTPA and captopril. Radiology. 176(2): 365-70, Aug 1990.

163. Stein PD, Alavi A, Gottschalk A, Hales CA, Saltzman HA, Vreim CE, Weg JG. Usefulness of

noninvasive diagnostic tools for diagnosis of acute pulmonary embolism in patients with a normal chest radiograph. American Journal of Cardiology. 67(13): 1117-20, May 1991.

164. Stein PD, Coleman RE, Gottschalk A, Saltzman HA, Terrin ML, Weg JG. Diagnostic utility of

ventilation/perfusion lung scans in acute pulmonary embolism is not diminished by pre-existing cardiac or pulmonary disease. Chest. 100(3): 604-6, Sep 1991.

165. Stein PD, Gottschalk A, Saltzman HA, Terrin ML. Diagnosis of acute pulmonary embolism in the

elderly. Journal of the American College of Cardiology. 18(6): 1452-7, Nov 1991. 166. Stein PD, Terrin ML, Gottschalk A, Alavi A, Henry JW. Value of ventilation/perfusion scans versus

perfusion scans alone in acute pulmonary embolism. American Journal of Cardiology. 69(14): 1239-41, May 1992.

167. Gottschalk A. Lung scan interpretation: a physiologic, user-friendly approach [editorial. Journal of

Nuclear Medicine. 33(7): 1422-4, Jul 1992. 168. Sostman HD, Gottschalk A. Prospective validation of the stripe sign in ventilation-perfusion

scintigraphy. Radiology. 184(2): 455-9, Aug 1992. 169. Gottschalk A, Juni JE, Sostman HD, Coleman RE, Thrall J, McKusick KA, Froelich JW, Alavi A.

Ventilation-perfusion scintigraphy in the PIOPED study. Part I. Data collection and tabulation. Journal of Nuclear Medicine. 34(7): 1109-18, Jul 1993.

170. Gottschalk A, Sostman HD, Coleman RE, Juni JE, Thrall J, McKusick KA, Froelich JW, Alavi A.

Ventilation-perfusion scintigraphy in the PIOPED study. Part II. Evaluation of the scintigraphic criteria and interpretations. Journal of Nuclear Medicine. 34(7): 1119-26, Jul 1993.

171. Stein PD, Henry JW, Gottschalk A. Mismatched vascular defects. An easy alternative to mismatched

segmental equivalent defects for the interpretation of ventilation/perfusion lung scans in pulmonary embolism. Chest. 104(5): 1468-71, Nov 1993.


172. Stein PD, Henry JW, Gottschalk A. The addition of clinical assessment to stratification according to prior cardiopulmonary disease further optimizes the interpretation of ventilation/perfusion lung scans in pulmonary embolism. Chest. 104(5): 1472-6, Nov 1993.

173. Stein P, Gottschalk A, Henry JW, Shivkumar K: Stratification of Patients According to Prior

Cardiopulmonary Disease: Approaches and probability Assessment Based on the Number of Mismatches Segmental Equivalent Perfusion Defects to Strengthen the Diagnostic Value of Ventilation/Perfusion Lung Scans in Acute Pulmonary Embolism. Chest, 104(5):1461-1467, 1993.

174. Gottschalk A, Harper PV: a triple-threat nuclear medicine pioneer [news]. Journal of Nuclear Medicine.

35(5): 17N-18N 20N, May 1994. 175. Gottschalk A. V/Q imaging and the diagnosis of PE: 'can we shift the gray to black and white?'

[editorial. Journal of Nuclear Medicine. 35(12): 1931-2, Dec 1994. 176. Stein PD, Gottschalk A. Critical review of ventilation/perfusion lung scans in acute pulmonary

embolism. Progress in Cardiovascular Diseases. 37(1): 13-24, 1994. 177. Smith KL, Daniels JL, Arnoczky SP, Dodds JA, Cooper TG, Gottschalk A, Shaw DA. Effect of joint

position and ligament tension on the MR signal intensity of the cruciate ligaments of the knee. Journal of Magnetic Resonance Imaging. 4(6): 819-22, 1994.

178. Stein PD, Gottschalk A: Letter to the Editor: Confession and Some Lessons, The PISA-PED Study,

Chest, Vol 108, November 1995, pp 1475-1477. 179. Stein PD, Dalen JE, Goldhaber SZ, Gottschalk A, Hull RD, Leeper KV, Moser KM, Raskob G,

Saltzman HA, Sostman HD, Tapson VF, Weg JG: Opinions Regarding the Diagnosis and Management of Venous Thromboembolic Disease. Chest, Vol. 109 (1), January 1996, pp 233-237.

180. Henry JW, Stein PD, Gottschalk A, Relyea B, Leeper KV Jr. Scintigraphic lung scans and clinical

assessment in critically ill patients with suspected acute pulmonary embolism. Chest. 109(2): 462-6, Feb 1996.

181. Stein PD, Relyea B, Gottschalk A. Evaluation of individual criteria for low probability interpretation of

ventilation-perfusion lung scans. Journal of Nuclear Medicine. 37(4): 577-81, Apr 1996. 182. Gottschalk A, Stein PD, Henry JW. Patient stratification by cardiopulmonary status in the diagnosis of

pulmonary embolism. Journal of Nuclear Medicine. 37(4): 570-2, Apr 1996. 183. Gottschalk A. The early years with Hal Anger. Seminars in Nuclear Medicine. 26(3): 171-9, Jul 1996. 184. Stein PD, Henry JW, Gottschalk A. Small perfusion defects in suspected pulmonary embolism. Journal

of Nuclear Medicine. 37(8):1313-6, Aug 1996. 185. Henry JW, Stein PD, Gottschalk A, Raskob GE. Pulmonary embolism among patients with a nearly

normal ventilation/perfusion lung scan. Chest. 110(2): 395-8, Aug 1996. 186. Gottschalk A, Stein PD, Henry JW, Relyea B. Can pulmonary angiography be limited to the most

suspicious side if the contralateral side appears normal on the ventilation/perfusion lung scan? Data from PIOPED. Prospective Investigation of Pulmonary Embolism Diagnosis. Chest. 110(2): 392-4, Aug 1996.


187. Gottschalk A, Stein PD, Henry JW, Relyea B. Matched ventilation, perfusion and chest radiographic abnormalities in acute pulmonary embolism. Journal of Nuclear Medicine. 37(10): 1636-8, Oct 1996.

188. Stein PD, Henry JW, Relyea B, Gottschalk A: Elderly Patients With No Prior Cardiopulmonary

Disease Show Ventilation/Perfusion Lung Scan Characteristics That Are Sensitive and Specific for Pulmonary Embolism. Am J Geriatric Cardiology, November/December 1996; 5(6):36-40.

189. Tryciecky EW, Gottschalk A, Ludema K. Oncologic imaging: interactions of nuclear medicine with CT

and MRI using the bone scan as a model. Seminars in Nuclear Medicine. 27(2): 142-51, Apr 1997. 190. Stein PD, Henry JW, Gottschalk A. Reassessment of pulmonary angiography for the diagnosis of

pulmonary embolism: relation of interpreter agreement to the order of the involved pulmonary arterial branch. Radiology. 210(3): 689-91, Mar 1999.

191. Ludman CN, Hough DO, Cooper TG, Gottschalk A. Silent meniscal abnormalities in athletes: magnetic

resonance imaging of asymptomatic competitive gymnasts. British Journal of Sports Medicine. 33(6): 414-6, Dec 1999.

192. Hull RD, Raskob GE, Brant RF, Pineo GF, Elliott G, Stein PD, Gottschalk A, Valentine KA, Mah AF.

Low-molecular-weight heparin vs heparin in the treatment of patients with pulmonary embolism. American-Canadian Thrombosis Study Group. Archives of Internal Medicine. 160(2): 229-36, Jan 2000.

193. Gottschalk A. The chronic perfusion defect: our knowledge is still hazy, but the message is clear

[comment]. Journal of Nuclear Medicine. 41(6): 1049-50, Jun 2000. 194. Stein PD, Gottschalk A. Review of criteria appropriate for a very low probability of pulmonary

embolism on ventilation-perfusion lung scans: a position paper. Radiographics. 20(1): 99-105, 2000. 195. Gottschalk A. New criteria for ventilation-perfusion lung scan interpretation: a basis for optimal

interaction with helical CT angiography. Radiographics. 20(4): 1206-10, 2000. 196. Gottschalk A. 1999 plenary session: Friday imaging symposium: algorithmic controversies.

Radiographics. 20(4): 1151-2, 2000. 197. Gottschalk A, Stein PD, Goodman LR, and Sostman HD. Overview of Prospective Investigation of

Pulmonary Embolism Diagnosis II. Seminars in Nuclear Medicine, 2002; 3(7):173-182. 198. Gottschalk A. In Memoriam: Paul V. Harper, MD, 1915-2005. The Journal of Nuclear Medicine,

2005; 46(10):19N. 199. Stine PD, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, Popovich J, Quinn

DA, Sos TA, Sostman HD, Tapson VF, Wakefield TW, Weg JG, Woodard PK. Multidetector Computer Tomography for Acute Pulmonary Embolism. N Engl J Med 2006;354:2317-27.

200. Stine PD, Beemath, A, Quinn D, Olson RE, Goodman LW, Gottschalk A, Hales CA, Hull RD, Leeper

KV, Sostman HD, Weg JG, Woodard PK. Usefulness of Multidetector Spiral Computed Tomography According to Age and Sex for Diagnosis of Acute Pulmonary Embolism. American Journal of Cardiology, 2007; May 1;99 (9):1303-5.



201. Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VK, Sostman H, Sos TA, Quinn DA, Leeper KV, Hull RD, Hales CA, Gottschalk A, Goodman LR, Fowler SE, Buckley JD. Diagnostic Pathways in Acute Pulmonar6 Embolism: recommendations of the PIOPED II Investigators. The American Journal of Medicine (2006) 119, 1048-1055.

202. Remy-Jardin M, Pistolesi M, Goodman LR, Gefter WB, Gottschalk A, Mayo JR, and Sostman HD.

Fleischner Society White Paper on PE. Radiology, November 1, 2007; 245(2):315-329. 203. Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VK, Sostman H, Sos TA, Quinn DA, Leeper

KV, Hull RD, Hales CA, Gottschalk A, Goodman LR, Fowler SE, Buckley JD. Diagnostic Pathways in Acute Pulmonar6 Embolism: recommendations of the PIOPED II Investigators. Radiology: Volume 242: Number 1, January 2007.

204. Stein PD, Beemath A, Matta F, Weg, JG, Yusen RD, Hales CA, Hull RD, Leeper KV, Sostman HD,

Tapson VF, Buckley JD, Gottschalk A, Goodman LW, Wakefied TW, Woodard PK. Clinical Characteristics of Patients with Acute Pulmonary Embolism: Data from PIOPED II. Am J Med 2007;120:871-879.

205. Stein PD, Beemath A, Quinn DA, Olson RE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper

KV, Sostman HD, Weg JD, Woodard PD. Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute pulmonary embolism. Am J Cardiol. 2007 May 1;99 (9):1303-5.

206. Sostman HD, Stein PD, Gottschalk A, Matta F, Hulll R, Goodman L. Acute Pulmonary Embolism:

Sensitivity and Specificity of Ventilation-Perfusion Scintigraphy in PIOPED II Study. Radiology: Volume 246: Number 3, March 2008, pp 941-946.

207. Gottschalk A, Stein PD, Sostman HD, Matta F, Beemath A. Very Low Probability Interpretation of

Ventilation-Perfusion Lung Scans in Combination with Low Probability Objective Clinical Assessment Reliably Excludes Pulmonary Embolism: Data from PIOPED II. J. Nucl. Med. 2007;48:1411-1415 J. Nucl. Med. 2007;48:1411-1415

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curriculum vitae alexander gottschalk, m.d

Health & Medicine

klinik und

regional wall

ambulatory

99m iron complex

99m sulfur

coronary artery

pass radionuclide

quantitative