CURRICULUM VITAE

Elena Padrell

Psychiatrist MD PhD

C/ San Lorenzo 30 PO Box 65 Reus, 43201 Lewes, DE 19958

Spain + 34 699 907256 USA+1 302 2453058

E-mail: padrell.elena@gmail.com

EDUCATION

• March2007-American Board of Psychiatry and Neurology recertification. #42592. 2007-2017

• Sept 2003 – Master Clinician Award in Psychopharmacology. Neurosciences Institute. University of San Diego

• April 1996 - American Board of Psychiatry and Neurology Certification

# 42592

• July 1989 - July 1993 -Resident trainee at Psychiatry Categorical Program. Department of Psychiatry, Mount Sinai Hospital, New York, NY

• Jan 1990 - PhD “cum laude” in Psychopharmacology by the

University of Barcelona, School of Medicine. Dissertation title:“Purification and functional characterization of the G proteins, serving as substrates of Bordettela Pertussis Toxin”. Experimental work done at the Department of Pharmacology of Mount Sinai School of Medicine, New York, NY. Thesis director: Dr. Ravi Iyengar, Ph.D Current chairman of Pharmacology Department.

• Jan 1987 - ECFMG certified.

• July 1981- Medical degree (MD license) by the Autonoma University of

Barcelona, School of Medicine. Spain

Latest CME credits: September 2015. Harvard Medical School. Attachment theory and Borderline Personality Disorder. 14,5 CME credits. Boston, MA September 2014. Updates on Depression, Anxiety and Stress. Harvard Medical School and McLean Hospital. Boston, MA. 14,5 CME credits.

August 2014. Paradigm shifts in Psychosis. Psychiatric Forum. Philadelphia, PA.4,5 CME credits. February , 2013 18th Annual Psychopharmacology Update . University of Nevada School of Medicine 22,50 credits. MEMBERSHIPS Spanish College of Physicians, since 1981 American Psychiatry Association, since 1992 American Medical Association, since 1993 Delaware Psychiatry Association, since 1993 International Psychogeriatric Association, since 1990 American Association of Private Practitioners, since 2002 LICENSES Delaware MD license # C1-0006472 DEAE State of DE # MD 3887 Fed DEAE # BP 7486233 WORK EXPERIENCE Clinical work: Sep 2011 to Present: Part time Solo Private Practice in general adult psychiatry. Psychopharmacology management and psychodynamic psychotherapy. Centre Passeig de Gracia, 12, 1. Barcelona 08007. Spain June 2015 to Oct 2015: Full time Locum tenens, C&L and In Pt attending psychiatrist at Christiana Care Health Center- Wilmington Hospital. Wilmington, DE. Jan 2006 to Nov 2014 : Part time Consultant psychiatrist with Department of Corrections. Ever since 2012, intermittent employee at Connections CSP Inc. Multiple short term assignments at different DE state correctional facilities;

Baylor women’s in New Castle, Howard Young in Wilmington and CSI in Georgetown, DE. USA. June 2013 to Oct 2013: Consultant leading psychiatrist at CAT. Mobile Crisis Assessment Treatment Team. Capital and Coast District Health Board. Wellington, New Zealand. (Global Medical Staffing independent contractor). June 2011 to Sep 2011: Certified Compensation and Disability Psychiatrist Examiner for all veterans. VA Hospital, Washington, DC. USA Jan 2002 to June 2011: Psychiatrist consultant for C&L and ER coverage at Beebe Medical Hospital, Lewes, DE. USA Feb 2011 to June 2011: Part time psychiatrist at Delaware Guidance Services. Clinical Psychiatric evaluations and treatment in a multidisciplinary approach of children and adolescents. Lewes, DE. USA June 2009 to Des 2010 : Full time leader Psychiatrist. Community Based Outpatient Clinic. Veterans Administration in Georgetown and Dover DE, USA Jan 2002 to May 2009: Full time private practice in general adult Psychiatry. Psychopharmacology management and psychodynamic psychotherapy in Lewes, Delaware. USA April 2003 to June 2006: Part time general adult psychiatrist for State of Delaware, Division of Substance Abuse and Mental Health, Georgetown Mental Health Clinic. Georgetown, DE. USA Sept 1998 to Des 2001: Solo Private practice in general adult and geriatric psychiatry. Psychopharmacology management and psychodynamic psychotherapy. Barcelona and Reus. Spain. During that time served as expert witness in different civil trials in Tarragona Court District, Spain. May 1999 to March 2001: Attending general adult Psychiatrist at Instituto Pedro Mata, Academic Psychiatric Hospital, affiliated with Rovira y Virgili University, School of Medicine, Reus, Spain. Sept 1998 to May 1999: Attending geriatric Psychiatrist at Complejo Assistencial Benito Menni, de San Boi de Llobregat. Academic Psychiatric institution, with a residency program.

July 1993 to Jan 1998: Medical Director. Inpatient Psychiatric Unit at Nanticoke Memorial Hospital, Seaford, Delaware. USA. General Adult inpatient psychiatry including ECT and C&L for the general hospital. Supervision of Chemical dependency rehabilitation program. July 1993 to Jan 1998: Solo Private Practice in General Adult Psychiatry, Seaford, Delaware. USA. Psychopharmacology management and psychodynamic psychotherapy. July 1993 to Jan 1998: Geriatric Psychiatry. Consultant for Lofland Park convalescent Home, Seaford, DE. Chancellor Care Center, Delmar, DE. Millsboro Nursing Home, Millsboro, DE. USA Dec 1992 to July 1993: Psychiatrist Consultant at Brooklyn Center for Psychotherapy and New Directions, New York, NY. Psychopharmacology management and psychotherapy with the Hispanic population in New York, USA July 1989 to July 1993: Resident trainee, Psychiatry Categorical Program, Department of Psychiatry, Mount Sinai Hospital and School of Medicine. 1 Levy place. New York, NY. USA. Oct 1986 to July 1989: Research Assistant (PhD), Department of Pharmacology, Mount Sinai Hospital and School of Medicine. New York, NY. USA. Oct 1984 to Oct 1986: Research Assistant, Department of Cell Biology. Baylor College of Medicine. Houston, TX. USA. June 1981 to Oct 1984: General family practice. Rural communities in Tarragona .Spain October 1982 to May 1983: General medicine and surgery as Volunteer MD at Holy Family Hospital, Ranchi, Bihar. INDIA Research Activities: 2012-2013 Participating investigator, with Parc Sanitari San Joan de Deu, Barcelona. At the European Innovation Partnership on Active and Healthy Ageing.

2004-2007 Participating investigator, Pfizer grant for open level study (clinical tudy phase IV), on side effect comparison of Olanzapine, Risperidone and Ziprasidone. - Participating investigator, Jansen grant for open level study on clinical monitoring of side effects of Risperdal consta. - Participating investigator, grant by Ciberonics for open level study on clinical monitoring and antidepressant response of patients with VNS implant 2000-2002 Clinical research directed by Dr E. Vieta in Clinic Hospital, Barcelona, Spain. Effectiveness of Quetiapine in manic symptoms of Bipolar I. Clinical monitoring of symptoms. Open level study. 1990- 1992 Mount Sinai psychiatry residency program, different clinical trials. One project involved measuring levels of HVA in CSF of schizophrenic patients under different conditions, prior and post neuroleptic treatment. 1984-1989 Full time basic research involving the biochemical purification and characterization of Gi proteins. Extraction from rat and bovine brain tissue. Multiple Gi activity function assays on different neurotransmitter systems, mainly Acetylcholine and Dopamine receptors. Cell Biology Dpt. at Baylor College of Medicine in Houston, TX (84-86). Pharmacology Dpt. at Mount Sinai School of Medicine, New York, NY(86-89). USA LANGUAGES

Proficiency: Spanish, Catalan and English. Reading / understanding: French and Italian.

PUBLICATIONS

• Vieta E, Parramon G, Padrell E, Nieto E, Martinez-Aran A, Corbella B,

Colom F, Reinares M, Goikolea JM, Torrent C: Quetiapine in the treatment of rapid cycling bipolar disorder. Bipolar Disorders 2002; 4:335–340

• Padrell, Elena, Carty, Donna J., Moriarty, Thomas M., Hildebrant, John

D., Landau, Emmanuel M., and Iyengar, Ravi. (1991) Two forms of the GTP- binding protein that stimulates Phospholipase C: Distinct Guanine Nucleotide binding properties. J. Biol. Chem. 1991 May 25; vol 266 (15): 9771-9777

• Senogles, Susan E., Spiegel, Allen M., Padrell, Elena, Iyengar, Ravi and

Caron Marc G. (1990). Specificity of Receptor –G protein interactions: Discrimination of G subtypes by the D2 dopamine receptor in a reconstituted system. J. Biol. Chem. 1990 March 15, vol 265 (8): 4507-4514.

• Moriarty, Thomas M, Padrell, Elena, Carty, Donna J., Omri, Gilla,

Landau, Emmanuel M., and Iyengar, Ravi. (1990). G Protein as signal transducer in the Pertussis Toxin sensitive phosphatidilinositol pathway.Nature 1990. Vol 343: 79-82

• Codina, Juan, Yatani, Atsuko, VanDongen, Anthony MJ., Padrell,

Elena, Carty, Donna J., Mattera, rafael, Brown, Arthur M., Iyengar, Ravi. Pertussis Toxin substrates. Studies with recombinant and native G Protein alfa subunit. In G Proteins , edited by Ravy Iyengar and Lutz Birmbaumer, San Diego, CA. Academic Press, Inc.

• Yatani, Atsuko, Mattera, Rafael, Codina, Juan, Graf, R., Padrell, Elena,

Iyengar, Ravi, Brown, AM.,Birmbaumer, Lutz. 1988. The G-Protein gated K + channel is stimulated by three distinct Gi alfa subunits. Nature 1988, vol 336: 680-682

• Padrell, Elena, Herberg, JT, Monastirky, Beatriz, Premont, Richard, and

Iyengar, ravi. (1986). The hepatic glucagon receptor. A comparative study of the regulatory and structural properties. Endocrinology. 1987, vol 120: 2316-2323.

• Codina, Juan, Graf, R., Padrell, Elena, Carty, Donna, and Mattera, Rafael (1988). The Gi Proteins. In G- Proteins edited by R. Iyengar and L. Birmbaumer. Academic Press, Inc., New York, NY.

• Carty, Donna, Padrell, Elena, Codina, Juan, Graf, R., Birmbaumer, Lutz,

Gilman, AG, and Iyengar, Ravi. (1990). Distinct guanine nucleotide binding and release properties of the three Gi proteins. J. Biol. Chem... 1990 Apr 15; 265 (11): 6268-6273.

• Padrell, Elena, Royal, B., Iyengar, R., and Green, J. (1988). Tricyclic

Antidepressants inhibit Guanine Nucleotide Stimulation of Brain Adenyl Cyclase. Submitted to Molecular Pharmacology

• Padrell, Elena. (1991). “Functional and biochemical characterization of

the G-proteins, that are substrates of Bordetella Pertussis toxin”. Micropublications, of doctorate thesis collection. Number 987. Edited by University of Barcelona.

Research interests Neurosciences. Basic Science. Psychopharmacology. Clinical trials involving the treatment of major neuropsychiatric disorders. Clinical Interest General adult outpatient psychiatry. Community psychiatry. Psychogeriatrics. Cross cultural Psychiatry.