current psoriasis situation in china zheng min , m.d. dermatology department second hospital...
TRANSCRIPT
![Page 1: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/1.jpg)
Current Psoriasis Current Psoriasis Situation in ChinaSituation in China
Zheng MinZheng Min ,, M.D.M.D.Dermatology DepartmentDermatology DepartmentSecond HospitalSecond HospitalZhejiang University, School of MedicineZhejiang University, School of Medicine浙江大学医学院附属第二医院郑敏浙江大学医学院附属第二医院郑敏
PSORIASIS 2010Congress of the Psoriasis International Network
PARIS, July 1-4, 2010Palais des Congrès
![Page 2: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/2.jpg)
Practical organisation of Chinese Psoriasis Network
National projects opportunitis to develop
international collaborations on specific topics
other issues
![Page 3: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/3.jpg)
Chairman Prof. Zhu Xuejun, Chinese Dermatologist Association
![Page 4: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/4.jpg)
Six National Psoriasis Center
Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College.Nanjing;
First Hospital Beijing Univerity.Beijing; Second Hospital Zhejiang
University.Hangzhou; Huashan Hospital, Fudan University.Shanghai; Xijing Hospital, Fourth Military Medical
University; Xi’an ; Peking Union Medical College Hospital.Beijing.
Chinese Psoriasis Network
![Page 5: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/5.jpg)
Geographic Coverage of 46 hospitals in China
未覆盖区域山西贵州四川西藏香港台湾
![Page 6: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/6.jpg)
Practical organisation of Chinese Psoriasis Network
National projects opportunitis to develop
international collaborations on specific topics
other issues
![Page 7: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/7.jpg)
World Psoriasis Day event Targeted Patients
Epidermological Investigation National Treatment Guideline
National projects
![Page 8: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/8.jpg)
![Page 9: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/9.jpg)
Press conference focus on national psoriasis prevention and treatment on 29. Oct.
![Page 10: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/10.jpg)
Prof. Zhu Xuejun, chairman of China Dermatologist Association, in Press conference in International day of Psoriasis
![Page 11: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/11.jpg)
![Page 12: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/12.jpg)
![Page 13: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/13.jpg)
![Page 14: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/14.jpg)
![Page 15: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/15.jpg)
Beijing
Shanghai
Hangzhou
46 hospitals in different cities of China
4879 cases of psoriasis
(2009.Nov.23-Dec. 12)●
●
●
●
●●
●
●
●
●
●●
●●
●●
●
●
●
●
●
●●
●
●
●●
● ●●
●
●
●
●
●
●●
●
●
●●
●
●
●
●
![Page 16: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/16.jpg)
New Data 2009New Data 2009
46 hospitals in China 4879 cases of psoriasis vulgaris Male, 61.14%; Female, 38.86% , Male : Female=1.57 : 1 Mean age 40.49±22.11
![Page 17: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/17.jpg)
Family history of psoriasis: 22.84% (1057/4628)
62.53 % in first degree relatives 62.53 % in first degree relatives 27.72 % in second degree relatives27.72 % in second degree relatives 9.76 % in third degree relativesin third degree relatives
Genetic epidemiologyGenetic epidemiology
![Page 18: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/18.jpg)
Peak age of first onsetPeak age of first onset
male: 20~29 years male: 20~29 years
female: 10~19 yearsfemale: 10~19 years
Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis VulgarisChinese Journal of Dermatology 2000;33(6):383-385.
![Page 19: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/19.jpg)
Psoriasis vulgaris may be a Psoriasis vulgaris may be a multigenic inheritable disease multigenic inheritable disease and the genetic factors play an and the genetic factors play an important role in the important role in the pathogenesis of psoriasis.pathogenesis of psoriasis.
Zhang XJ et al: Analyses of Genetic Epidemiology of Psoriasis VulgarisChinese Journal of Dermatology 2000;33(6):383-385.
![Page 20: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/20.jpg)
Causative factorCausative factor
Psychological factorPsychological factor
Infection, wound
Alcohol, diet, smoking, drug
Endocrine and metabolic diseaseEndocrine and metabolic disease
![Page 21: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/21.jpg)
Relapse and aggratateRelapse and aggratate
Season, especially winter (83.36%)
Psychological factor
Pharyngolaryngitis or tonsillitisPharyngolaryngitis or tonsillitis
Alcohol and food
Medicine and smoking
![Page 22: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/22.jpg)
Releave SeasonReleave Season
Summer ( 90.56% )
Spring
Paracmasia: 14.06±37.93 m
![Page 23: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/23.jpg)
Clinical Type of psoriasis Clinical Type of psoriasis in China in China Psoriasis vulgaris: 4489 ( 92.01% ) Guttae 26.09% Plaque 57.01% Mix 16.91% Psoriasis pustulosa: 169 ( 3.46% ) Psoriasis erythroderma: 79 ( 1.62% ) Psoriasis arthropathica: 142 例( 2.91% )。
![Page 24: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/24.jpg)
19.67%: 932/4737 have accompanied disease
High blood pressure: 576 ( 12.16% ) Diabetes: 237 ( 5.00% ) Coronary heart disease:149 ( 3.15% ) Hyperlipemia: 340 ( 7.18% ) Rheumatoid arthritis: 61 ( 1.29% ), Tumor: 40 ( 0.84% )。
ComorbiditiesComorbidities in psoriatic patientsin psoriatic patients
![Page 25: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/25.jpg)
ManagementManagement
Systemic therapy;Systemic therapy;
Topical therapy;Topical therapy;
Patient education.Patient education.
![Page 26: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/26.jpg)
79.55% (3809/4788)79.55% (3809/4788) Traditional Chinese Medicine Traditional Chinese Medicine
89.47% 89.47% Acitretin Acitretin 22.06% 22.06%
MTX 5.64%MTX 5.64%
Immunosupressants 14.02%Immunosupressants 14.02%
Steroids 13.30%Steroids 13.30%
Others 27.59%Others 27.59%
Systemic treatmentSystemic treatment
![Page 27: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/27.jpg)
Systemic treatmentSystemic treatment
Methotrexate 7.5mg/weekMethotrexate 7.5mg/week widespread plaque, senile personwidespread plaque, senile person Acitretin 0.5mg/kg.dAcitretin 0.5mg/kg.d erythroderma and pustular psoriasiserythroderma and pustular psoriasis Cyclosporin A 5mg/kg.d psoriasis arthritisCyclosporin A 5mg/kg.d psoriasis arthritis Corticosteroids.Corticosteroids. BiologicsBiologics Alternative therapy TCMAlternative therapy TCM
![Page 28: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/28.jpg)
Topical therapyTopical therapy
90.34% (4283/4741)90.34% (4283/4741) Topical steroids: 85.59%Topical steroids: 85.59%
Vitamin D3 analogue: 31.64%Vitamin D3 analogue: 31.64%
Topical retinoids: 27.01%Topical retinoids: 27.01%
Salicylic acid: 18.98%Salicylic acid: 18.98%
Coal tar: 14.57%Coal tar: 14.57%
Anthralin: 3.34%Anthralin: 3.34%
Topical TCM: 23.67%Topical TCM: 23.67%
Others: 25.40%Others: 25.40%
![Page 29: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/29.jpg)
Physical therapyPhysical therapy
26.54%: 124426.54%: 1244//46884688 NB-UVB NB-UVB >> 50%50%
UVBUVB
PUVAPUVA
![Page 30: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/30.jpg)
Insurance and treatment costs Insurance and treatment costs
71.2% patients have a social medical 71.2% patients have a social medical insurance (non-commercial), and insurance (non-commercial), and 7.43% patients attend other 7.43% patients attend other commercial medical insurancecommercial medical insurance
In the past 6 months, about 29.84% In the past 6 months, about 29.84% went to see a dermatologist 6 times. went to see a dermatologist 6 times. The mean fees is $101±2000, and The mean fees is $101±2000, and about $52±100 were paid by patients about $52±100 were paid by patients themselvesthemselves 。。
![Page 31: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/31.jpg)
Insurance and treatment costsInsurance and treatment costs
In the past 2 years, 7.07% patients were In the past 2 years, 7.07% patients were accepted in the hospital and 0.21% were in accepted in the hospital and 0.21% were in the hospital more than 6 times. the hospital more than 6 times.
The duration in the hospital is 27.26±46.27dThe duration in the hospital is 27.26±46.27d,, mean spent is $1100±1200mean spent is $1100±1200 ,, and the and the patients themselves have to pay $600±1000patients themselves have to pay $600±1000
![Page 32: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/32.jpg)
QOL
18.73% patients were affected severely, 29.45% moderately , and 37.56% slightly. Only 14.27% were unaffected.
13.31% patients’ family expenditure were affected greatly, 25.96% moderately, 38.90% slightly and 21.82% unaffected.
![Page 33: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/33.jpg)
Update our National Treatment Guideline according to the new data from evidence based medicine:
National Disease Registration; National Epi Invetigation; International co-operation.
More to do
![Page 34: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/34.jpg)
Practical organisation of Chinese Psoriasis Network
National projects Opportunitis to develop
international collaborations on specific topics and other issues
![Page 35: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/35.jpg)
Comparison study on the background between Eastern and Western in genetics and clinical pattern background
Some mechanism study on traditional Chinese Medicine on psoriasis
…….
![Page 36: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/36.jpg)
THANK YOU !THANK YOU !
Beijing
ShanghaiHangzhou
![Page 37: Current Psoriasis Situation in China Zheng Min , M.D. Dermatology Department Second Hospital Zhejiang University, School of Medicine 浙江大学医学院附属第二医院郑敏](https://reader033.vdocuments.mx/reader033/viewer/2022061322/56649e395503460f94b2a186/html5/thumbnails/37.jpg)
Zhejiang Univ. School of Zhejiang Univ. School of Med.Med.