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Current Awareness in Clinical Toxicology is produced monthly for the American

Academy of Clinical Toxicology by the Birmingham Unit of the UK National Poisons

Information Service, with contributions from the Cardiff, Edinburgh, and Newcastle

Units.

The NPIS is commissioned by Public Health England

Current Awareness in

Clinical Toxicology Editors: Damian Ballam MSc and Allister Vale MD

July 2014

CURRENT AWARENESS PAPERS OF THE MONTH

Systemic toxicity related to metal hip prostheses

Bradberry SM, Wilkinson JM, Ferner RE. Clin Toxicol 2014; online early: doi: 10.3109/15563650.2014.944977:

Introduction

One in eight of all total hip replacements requires revision within 10 years, 60% because of wear-related complications. The bearing surfaces may be made of cobalt/chromium, stainless steel, ceramic, or polyethylene. Friction between bearing surfaces and corrosion of non-moving parts can result in increased local and systemic metal concentrations.

Objectives

To identify and systematically review published reports of systemic toxicity attributed to metal released from hip implants and to propose criteria for the assessment of these patients.

Methods

Medline (from 1950) and Embase (from 1980) were searched to 28 February 2014 using the search terms (text/abstract) chrom* or cobalt* and [toxic* or intox* or poison* or adverse effect or complication] and [prosthes* or 'joint replacement' or hip or arthroplast*] and PubMed (all available years) was searched using the search term (("chromium/adverse effects" [Mesh] OR "Chromium/poisoning" [Mesh] OR "Chromium/toxicity"[Mesh]) OR ("Cobalt/adverse effects"[Mesh] OR "Cobalt/poisoning"[Mesh] OR "Cobalt/toxicity"[Mesh])) AND ("Arthroplasty, Replacement, Hip"[Mesh] OR "Hip Prosthesis"[Mesh]). These searches identified 281 unique references, of which 23 contained original case data. Three further reports were identified from the bibliographies of these papers. As some cases were reported repeatedly the 26 papers described only 18 individual cases.

Systemic toxicity

Ten of these eighteen patients had undergone revision from a ceramic-containing bearing to one containing a metal component. The other eight had metal-on-metal prostheses.

2

Systemic toxicity was first manifest months and often several years after placement of the metal-containing joint. The reported systemic features fell into three main categories: neuro-ocular toxicity (14 patients), cardiotoxicity (11 patients) and thyroid toxicity (9 patients). Neurotoxicity was manifest as peripheral neuropathy (8 cases), sensorineural hearing loss (7) and cognitive decline (5); ocular toxicity presented as visual impairment (6). All these neurological features, except cognitive decline, have been associated with cobalt poisoning previously.

Type of prosthesis and blood metal concentrations

Where blood or serum metal concentrations were reported (n = 17 for cobalt and n = 14 for chromium), the median cobalt concentration was 398 (range, 13.6 – 6521) μg/L and the median chromium concentration was 48 μg/L (in whole blood) (range, 4.1 – 221 μg/L including serum and blood values). Those patients reported to have systemic features who had received a metal-on-metal prosthesis (n = 8) had a median peak blood cobalt concentration of 34.5 (range, 13.6 – 398.6) μg/L; those with a metal-containing revision of a failed ceramic prosthesis (n = 10) had a median blood cobalt concentration of 506 (range, 353 – 6521) μg/L.

Management

The most common treatment was removal of the metal-containing prosthesis, undertaken in all but 2 patients. This was usually associated with a fall in circulating cobalt concentration and improvement in some or all features.

Clinical and toxicological assessment of systemic features

We propose the following criteria for assessing the likelihood that clinical features are related to cobalt toxicity: clinical effects consistent with the known neurological, cardiac, or thyroidal effects of cobalt, and for which any other explanation is less likely; increased blood cobalt concentrations (substantially higher than those in patients with well-functioning prostheses) several months after hip replacement; a fall in the blood cobalt concentration after treatment, usually accompanied by signs of improvement in features. When judged by these criteria, the systemic features in 10 of the reported cases are likely to be related to cobalt exposure from a metal-containing hip prosthesis.

Conclusions

Rarely, patients exposed to high circulating concentrations of cobalt from failed hip replacements develop neurological damage, hypothyroidism and/or cardiomyopathy, which may not resolve completely even after removal of the prosthesis. The greatest risk of systemic cobalt toxicity seems to result from accelerated wear of a cobalt-containing revision of a failed ceramic prosthesis, rather than from primary failure of a metal-on-metal prosthesis.

Full text available from: http://dx.doi.org/10.3109/15563650.2014.944977

Increasing frequency of severe clinical toxicity after use of 2,4-dinitrophenol in the UK: a report from the National Poisons Information Service

Kamour A, George N, Gwynnette D, Cooper G, Lupton D, Eddleston M, Thompson JP, Vale JA, Thanacoody HKR, Hill S, Thomas SHL. Emerg Med J 2014; online early: doi: 10.1136/emermed-2013-203335:

Abstract and full text available from: http://dx.doi.org/10.1136/emermed-2013-203335

http://dx.doi.org/10.3109/15563650.2014.944977

3

Management of pediatric snake bites: are we doing too much?

Correa JA, Fallon SC, Cruz AT, Grawe GH, Vu PV, Rubalcava DM, Kaziny B, Naik-Mathuria BJ, Brandt ML. J Pediatr Surg 2014; 49: 1009-15.

Abstract and full text available from: http://dx.doi.org/10.1016/j.jpedsurg.2014.01.043

Potential antidotes for reversal of old and new oral anticoagulants

Suryanarayan D, Schulman S. Thromb Res 2014; 133 Suppl 2: S158-S166.

Abstract and full text available from: http://dx.doi.org/10.1016/S0049-3848(14)50026-6

Neurofunctional dopaminergic impairment in elderly after lifetime exposure to manganese

Lucchini RG, Guazzetti S, Zoni S, Benedetti C, Fedrighi C, Peli M, Donna F, Bontempi E, Borgese L, Micheletti S, Ferri R, Marchetti S, Smith DR. Neurotoxicology 2014; online early: doi: 10.1016/j.neuro.2014.05.006:

Abstract and full text available from: http://dx.doi.org/10.1016/j.neuro.2014.05.006

Antidepressant use in pregnancy and the risk of cardiac defects

Huybrechts KF, Palmsten K, Avorn J, Cohen LS, Holmes LB, Franklin JM, Mogun H, Levin R, Kowal M, Setoguchi S, Hernández-Díaz S. N Engl J Med 2014; 370: 2397-407.

Abstract and full text available from: http://dx.doi.org/10.1056/NEJMoa1312828

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TOXICOLOGY General Bertomeu-Sánchez JR.

Classrooms, salons, academies, and courts: Mateu Orfila (1787–1853) and nineteenth-century French toxicology.

Ambix 2014; 61: 162-86.

Donner A.

Toxicology: toxicity biomaps.

Nat Chem Biol 2014; 10: 485.

Gorenjak M.

Clinical chemist's interpretative competence in toxicology.

Biochem Med (Zagreb) 2014; 24: A2-A3.

Nader MA, Balster RL, Henningfield JE.

William L. Woolverton: a case history in unraveling the behavioral pharmacology of stimulants.

Neuropharmacology 2014; online early:

doi: 10.1016/j.neuropharm.2014.05.004:

Sherhod R, Judson P, Hanser T, Vessey J, Webb SJ, Gillet V.

Emerging pattern mining to aid toxicological knowledge discovery.

J Chem Inf Model 2014; online early:

doi: 10.1021/ci5001828:

Withington P.

The art of intoxication.

Lancet 2014; 383: 2118-9.

Analytical toxicology Abdissa A, Wiesner L, McIlleron H, Friis H, Andersen AB, Kæstel P.

Evaluation of an immunoassay for determination of plasma efavirenz concentrations in resource-limited settings.

J Int AIDS Soc 2014; 17: 18979.

Barnes AJ, Young S, Spinelli E, Martin TM, Klette KL, Huestis MA.

Evaluation of a homogenous enzyme immunoassay for the detection of synthetic cannabinoids in urine.

Forensic Sci Int 2014; 241: 27-34.

Behonick G, Shanks KG, Firchau DJ, Mathur G, Lynch CF, Nashelsky M, Jaskierny DJ, Meroueh C.

Four postmortem case reports with quantitative detection of the synthetic cannabinoid, 5F-PB-22.

J Anal Toxicol 2014; online early:

doi: 10.1093/jat/bku048:

Belsey SL, Couchman L, Flanagan RJ.

Buprenorphine detection in urine using liquid chro-matography-high-resolution mass spectrometry: comparison with cloned enzyme donor immunoassay (ThermoFisher) and homogeneous enzyme immunoassay (Immunalysis).


doi: 10.1093/jat/bku060:

Espy RD, Teunissen B, Manicke NE, Ren Y, Ouyang Z, van Asten A, Cooks RG.

Paper spray and extraction spray mass spectrometry for the direct and simultaneous quantification of eight drugs of abuse in whole blood.

Anal Chem 2014; online early: doi: 10.1021/ac5016408:

Fernández MD, Di Fazio V, Wille SM, Kummer N, Samyn N.

A quantitative, selective and fast ultra-high performance liquid chromatography tandem mass spectrometry method for the simultaneous analysis of 33 basic drugs in hair (amphetamines, cocaine, opiates, opioids and metabolites).

J Chromatogr B Biomed Sci Appl 2014; 965: 7-18.

Fernández MdMR, Van Durme F, Wille SMR, Di Fazio V, Kummer N, Samyn N.

Validation of an automated solid-phase extraction method for the analysis of 23 opioids, cocaine, and metabolites in urine with ultra-performance liquid chromatography-tandem mass spectrometry.

J Anal Toxicol 2014; 38: 280-8.

Helfer AG, Turcant A, Boels D, Ferec S, Lelièvre LG, Welter J, Meyer MR, Maurer HH.

Elucidation of the metabolites of the novel psychoactive substance 4-methyl-N-ethyl-cathinone (4-MEC) in human urine and pooled liver microsomes by GC-MS and LC-HR-MS/MS techniques and of its detectability by GC-MS or LC-MSn standard screening approaches.

Drug Test Anal 2014; online early:

doi: 10.1002/dta.1682:

Imbert L, Boucher A, Delhome G, Cueto T, Boudinaud M, Maublanc J, Dulaurent S, Descotes J, Lachâtre G, Gaulier J-M.

Analytical findings of an acute intoxication after inhalation of methoxetamine.


doi: 10.1093/jat/bku052:

Kang S, Oh SM, Chung KH, Lee S.

A surrogate analyte-based LC-MS/MS method for the determination of -hydroxybutyrate (GHB) in human urine

and variation of endogenous urinary concentrations of GHB.

J Pharm Biomed Anal 2014; 98: 193-200.

Logan BK, Mohr AL, Talpins SK.

Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.


doi: 10.1093/jat/bku050:

Norlen H, Worth AP, Gabbert S.

A tutorial for analysing the cost-effectiveness of alternative methods for assessing chemical toxicity: the case of acute oral toxicity prediction.

Altern Lab Anim 2014; 42: 115-27.

Quinete N, Schettgen T, Bertram J, Kraus T.

Analytical approaches for the determination of PCB metabolites in blood: a review.

Anal Bioanal Chem 2014; online early:

doi: 10.1007/s00216-014-7922-5:

Suh-Lailam BB, Haglock-Adler CJ, Carlisle HJ, Ohman T, McMillin GA.

Reference interval determination for anabasine: a biomarker of active tobacco use.


doi: 10.1093/jat/bku059:

Thevis M, Piper T, Geyer H, Thomas A, Schaefer MS, Kienbaum P, Schänzer W.

Measuring xenon in human plasma and blood by gas chromatography/mass spectrometry.

Rapid Commun Mass Spectrom 2014; 28: 1501-6.

5

Analytical toxicology

Zhang M, Deng M, Ma J, Wang X.

An evaluation of acute hydrogen sulfide poisoning in rats through serum metabolomics based on gas chro-matography-mass spectrometry.

Chem Pharm Bull 2014; 62: 505-7.

Biomarkers de Castro NSS, de Oliviera Lima M.

Biomarkers of mercury exposure in the Amazon.

BioMed Res Int 2014; 2014: 867069.

Huang P, Ren X, Huang Z, Yang X, Hong W, Zhang Y, Zhang H, Liu W, Huang H, Huang X, Wu D, Yang L, Tang H, Zhou L, Li X, Liu J.

Serum proteomic analysis reveals potential serum biomarkers for occupational medicamentosa-like dermatitis caused by trichloroethylene.

Toxicol Lett 2014; 229: 101-10.

Ibrahim KS, Amer NM, El-dossuky EA, Emara AM, El-Fattah AESM, Shahy EM.

Hematological effect of benzene exposure with emphasis of muconic acid as a biomarker.

Toxicol Ind Health 2014; 30: 467-74.

Krautter GR, Borgerding MF.

Comparison of consumption patterns, biomarkers of exposure and subjective effects in cigarette smokers switched to dissolvable tobacco (camel orbs), dual use, or tobacco abstinence.

Nicotine Tob Res 2014; online early:

doi: 10.1093/ntr/ntu082:

Leng G, Koch HM, Gries W, Schütze A, Langsch A, Brüning T, Otter R.

Urinary metabolite excretion after oral dosage of bis(2-propylheptyl)phthalate (DPHP) to five male volunteers – Characterization of suitable biomarkers for human biomonitoring.

Toxicol Lett 2014; online early:

doi: 10.1016/j.toxlet.2014.06.035:

Carcinogenicity Ahrens W, Merletti F, Mirabelli D.

Biliary tract cancer in male printers and typesetters in the European rare cancer case-control study.

Occup Environ Med 2014; online early:

doi: 10.1136/oemed-2014-102322:

Aiso S, Take M, Kasai T, Senoh H, Umeda Y, Matsumoto M, Fukushima S.

Inhalation carcinogenicity of dichloromethane in rats and mice.

Inhal Toxicol 2014; 26: 435-51.

Choi W-I, Jung HR, Shehu E, Rho BH, Lee M-Y, Kwon KY.

Small airway-centered granulomatosis caused by long-term exposure to polytetrafluoroethylene.

Chest 2014; 145: 1397-402.

Colt JS, Friesen MC, Stewart PA, Donguk P, Johnson A, Schwenn M, Karagas MR, Armenti K, Waddell R, Verrill C, Ward MH, Beane Freeman LE, Moore LE, Koutros S, Baris D, Silverman DT.

A case-control study of occupational exposure to metal-working fluids and bladder cancer risk among men.


doi: 10.1136/oemed-2013-102056:

Gibbs GW, Labrèche F. Cancer risks in aluminum reduction plant workers: a review. J Occup Environ Med 2014; 56: S40-S59.

Hamra GB, Guha N, Cohen A, Laden F, Raaschou-Nielsen O, Samet JM, Vineis P, Forastiere F, Saldiva P, Yorifuji T, Loomis D. Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1408092: Laborde-Castérot H, Laurier D, Caër-Lorho S, Etard C, Acker A, Rage E. Chest X-ray screening examinations among French uranium miners: exposure estimation and impact on radon-associated lung cancer risk. Occup Environ Med 2014; online early: doi: 10.1136/oemed-2013-101937:

Puett RC, Hart JE, Yanosky JD, Spiegelman D, Wang M, Fisher JA, Hong B, Laden F. Particulate matter air pollution exposure, distance to road, and incident lung cancer in the nurses' health study cohort. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307490: Rietjens IMCM, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Marnett LJ, Smith B, Adams T, Bastaki M, Harman C, Taylor S. The impact of structural and metabolic variation on the toxicity and carcinogenicity of hydroxy- and alkoxy- substituted allyl- and propenylbenzenes. Chem Res Toxicol 2014; online early: doi: 10.1021/tx500109s:

Rota M, Bosetti C, Boccia S, Boffetta P, La Vecchia C. Occupational exposures to polycyclic aromatic hydrocarbons and respiratory and urinary tract cancers: an updated systematic review and a meta-analysis to 2014. Arch Toxicol 2014; online early: doi: 10.1007/s00204-014-1296-5: Ward MH, Colt JS, Deziel NC, Whitehead TP, Reynolds P, Gunier RB, Nishioka M, Dahl GV, Rappaport SM, Buffler PA, Metayer C. Residential levels of polybrominated diphenyl ethers and risk of childhood acute lymphoblastic leukemia in California. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307602:

Cardiotoxicity Chrysant SG, Chrysant GS. Cardiovascular complications from consumption of high energy drinks: recent evidence. J Hum Hypertens 2014; online early: doi: 10.1038/jhh.2014.47: Fathallah I, Brahmi N, Nadia N, Mrad A, Amamou M. Cardiovascular accidents during acute carbon monoxide poisoning. Eur J Heart Fail 2014; 16: 334-5. Ibrahim S, Al-Saffar F, Wannenburg T. A unique case of cardiac arrest following K2 abuse. Case Rep Cardiol 2014; 2014: 120607. Jung Y-S, Lee J-S, Min Y-G, Park J-S, Jeon W, Park E-J, Shin J-H, Oh S, Choi S-C. Carbon monoxide-induced cardiomyopathy – Epidemiology, clinical characteristics and prognosis –. Circ J 2014; 78: 1437-44.

6

Cardiotoxicity

Kemp AH, Outhred T, Saunders S, Brunoni AR, Nathan PJ, Malhi GS.

Impact of escitalopram on vagally mediated cardiovascular function in healthy participants: implications for under-standing differential age-related, treatment emergent effects.

Psychopharmacology 2014; 231: 2281-90.

Kitami M, Oizumi H, Kish SJ, Furukawa Y.

Takotsubo cardiomyopathy associated with lithium in-toxication in bipolar disorder: a case report.

J Clin Psychopharmacol 2014; 34: 410-1.

Koller AC, Salcido DD, Callaway CW, Menegazzi JJ.

Resuscitation characteristics and outcomes in suspected drug overdose-related out-of-hospital cardiac arrest.

Resuscitation 2014; online early:

doi: 10.1016/j.resuscitation.2014.05.036:

Liao F, Wang L, Qin SK, Li XW, Yang NR, Yao L, Zhang Y, Xun C, Yan F.

Cardiac toxicity caused by fluorouracil: a report of 9 cases and review of literature.

J Pract Oncol 2014; 29: 183-5.

Odom DM, Mladsi DM, Saag KG, Sherif BN, Miles L, Ronquest N, Wang J.

Relationship between diclofenac dose and risk of gastro-intestinal and cardiovascular events: meta-regression based on two systematic literature reviews.

Clin Ther 2014; 36: 906-17.

Pape E, Roman E, Frikha Z, Scala-Bertola J, Tournebize J, Bornert-Keller N, Gibaja V, Petitpain N, Moulin F, Gambier N, Kahn JP.

Acute myocardial infarction in a cannabis smoker: role of cannabis?

Fundam Clin Pharmacol 2014; 28: 57.

Raj S, Franco VI, Lipshultz SE.

Anthracycline-induced cardiotoxicity: a review of patho-physiology, diagnosis, and treatment.

Curr Treat Options Cardiovasc Med 2014; 16: 315.

Riha M, Voprsalová M, Pilarová V, Semecky V, Holecková M, Vávrová J, Palicka V, Filipsky T, Hrdina R, Nováková L, Mladenka P.

Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity.

Naunyn Schmiedebergs Arch Pharmacol 2014; online early: doi: 10.1007/s00210-014-0995-z:

Tsuji JS, Perez V, Garry MR, Alexander DD.

Association of low-level arsenic exposure in drinking water with cardiovascular disease: a systematic review and risk assessment.

Toxicology 2014; 323: 78-94.

Dermal toxicity Antoine SM, Banas E, Keogh S.

A rare case of toxic epidermal necrolysis (TEN) associated with the use of azithromycin.

J Gen Intern Med 2014; 29: S282-S283.

Boogaard PJ, van Puijvelde MJP, Urbanus JH.

Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.


doi: 10.1016/j.toxlet.2014.05.014:

Heeren Neto AS, Bernardes FF, Martins G.

Skin lesions simulating blue toe syndrome caused by prolonged contact with a millipede.

Rev Soc Bras Med Trop 2014; 47: 257-8.

Mcclanahan C, Asarch A, Swick BL.

Black spot poison ivy.

Int J Dermatol 2014; 53: 752-3.

Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM.

Percutaneous absorption and distribution of organo-phosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model.

Toxicol Lett 2014; 229: 66-72.

Schulte S, Barkema LW, Kardaun SH.

Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12).

J Dtsch Dermatol Ges 2014; 12: 502-4.

Unal E, Balta I, Bozkurt O.

Lichen striatus: after a bite by bumblebee.

Cutan Ocul Toxicol 2014; online early:

doi: 10.3109/15569527.2014.910804:

Wang X, Zhang Y, Ni L, You C, Ye C, Jiang R, Liu L, Liu J, Han C.

A review of treatment strategies for hydrofluoric acid burns: current status and future prospects.

Burns 2014; online early: doi: 10.1016/j.burns.2014.04.009:

Developmental toxicology Bukowski J.

Critical review of the epidemiologic literature regarding the association between congenital heart defects and exposure to trichloroethylene.

Crit Rev Toxicol 2014; online early:

doi: 10.3109/10408444.2014.910755:

Cantilino A, Lorenzo L, de Paula JA, Einarson A.

Use of psychotropic medications during pregnancy: perception of teratogenic risk among physicians in two Latin American countries.

Rev Bras Psiquiatr 2014; 36: 106-10.

Chen A, Yolton K, Rauch SA, Webster GM, Hornung R, Sjödin A, Dietrich KN, Lanphear BP.

Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. Children through 5 years of age: the HOME Study.

Environ Health Perspect 2014; online early:

doi: 10.1289/ehp.1307562:

Feldman V.

Neurodevelopmental toxicity: still more questions than answers.

Lancet Neurol 2014; 13: 645-6.

Frederiksen H, Kuiri-Hänninen T, Main KM, Dunkel L, Sankilampi U.

A longitudinal study of urinary phthalate excretion in 58 full-term and 67 preterm infants from birth through 14 months. Environ Health Perspect 2014; online early:

doi: 10.1289/ehp.1307569:

Gelinas J, Allukian M, Jr.



7

Developmental toxicology

Goldstein DA, Saltmiras DA.


Lancet Neurol 2014; 13: 645.

Grandjean P, Landrigan PJ.

Neurodevelopmental toxicity: still more questions than answers - authors' response.


Gray BA, Holland C.

Implications of psychoactive 'bath salts' use during pregnancy.

Nurs Womens Health 2014; 18: 220-30.

Hayashi Y, Ito Y, Nakajima T.

Effects of exposure to di(2-ethylhexyl)phthalate during fetal period on next generation.

Nihon Eiseigaku Zasshi 2014; 69: 86-91.

Hui JY, Hoffmann M, Kumar G.

Embryo-fetal exposure and developmental outcome of thalidomide following oral and intravaginal administration to pregnant rabbits.

Reprod Toxicol 2014; online early:

doi: 10.1016/j.reprotox.2014.05.002:

Huybrechts KF, Palmsten K, Avorn J, Cohen LS, Holmes LB, Franklin JM, Mogun H, Levin R, Kowal M, Setoguchi S, Hernández-Díaz S.

Antidepressant use in pregnancy and the risk of cardiac defects.

N Engl J Med 2014; 370: 2397-407.

Kay VR, Bloom MS, Foster WG.

Reproductive and developmental effects of phthalate diesters in males.

Crit Rev Toxicol 2014; 44: 467-98.

Komada M, Itoh S, Kawachi K, Kagawa N, Ikeda Y, Nagao T.

Newborn mice exposed prenatally to bisphenol A show hyperactivity and defective neocortical development.

Toxicology 2014; 323: 51-0.

Manduca P, Naim A, Signoriello S.

Specific association of teratogen and toxicant metals in hair of newborns with congenital birth defects or developmentally premature birth in a cohort of couples with documented parental exposure to military attacks: observational study at Al Shifa Hospital, Gaza, Palestine.

Int J Environ Res Public Health 2014; 11: 5208-23.

Nishioka E, Yokoyama K, Matsukawa T, Vigeh M, Hirayama S, Ueno T, Miida T, Makino S, Takeda S.

Evidence that birth weight is decreased by maternal lead levels below 5g/dl in male newborns.

Reprod Toxicol 2014; 47: 21-6.

Patelarou E, Kelly FJ.

Indoor exposure and adverse birth outcomes related to fetal growth, miscarriage and prematurity – A systematic review.


Pereira G, Bell ML, Lee HJ, Koutrakis P, Belanger K.

Sources of fine particulate matter and risk of preterm birth in Connecticut, 2000–2006: a longitudinal study.


doi: 10.1289/ehp.1307741:

Rappazzo KM, Daniels JL, Messer LC, Poole C, Lobdell DT.

Exposure to fine particulate matter during pregnancy and risk of preterm birth among women in New Jersey, Ohio, and Pennsylvania, 2000-2005.


doi: 10.1289/ehp.1307456:

Sathiya S, Ganesh M, Kalaivani P, Ranju V, Janani S, Pramila B, Saravana Babu C.

Prenatal exposure to lamotrigine: effects on postnatal development and behaviour in rat offspring.

ISRN Neurosci 2014; 2014: 163459.

Shelton JF, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz B, Hansen RL, Hertz-Picciotto I.

Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: the CHARGE Study.


doi: 10.1289/ehp.1307044:

Tanaka S, Asahina Y, Satoh H, Miki A, Hori S, Sawada Y.

Questionnaire survey about NSAIDs use in late pregnancy for pharmacists and physicians.

Yakugaku Zasshi 2014; 134: 757-66.

Wang B, Yi D, Jin L, Li Z, Liu J, Zhang Y, Qiu X, Liu W, Tao S, Ren A.

Organochlorine pesticide levels in maternal serum and risk of neural tube defects in offspring in Shanxi Province, China: a case-control study.

Sci Total Environ 2014; 490: 1037-43.

Wendroff AP.



Yoshimasu K, Kiyohara C, Takemura S, Nakai K.

A meta-analysis of the evidence on the impact of prenatal and early infancy exposures to mercury on autism and attention deficit/hyperactivity disorder in the childhood.

Neurotoxicology 2014; online early:

doi: 10.1016/j.neuro.2014.06.007:

Yuan Q, Rubic M, Seah J, Rae C, Wright IM, Kaltenbach K, Feller JM, Abdel-Latif ME, Chu C, Oei JL, BOB COLLABORATIVE GROUP.

Do maternal opioids reduce neonatal regional brain volumes? A pilot study.

J Perinatol 2014; online early: doi: 10.1038/jp.2014.111:

Zhang J, Yoshinaga J, Hisada A, Shiraishi H, Shimodaira K, Okai T, Koyama M, Watanabe N, Suzuki E, Shirakawa M, Noda Y, Komine Y, Ariki N, Kato N.

Prenatal pyrethroid insecticide exposure and thyroid hormone levels and birth sizes of neonates.

Sci Total Environ 2014; 488-489: 275-9.

Driving under the influence of alcohol and other drugs Bezemer KDB, Smink BE, van Maanen R, Verschraagen M, de Gier JJ.

Prevalence of medicinal drugs in suspected impaired drivers and a comparison with the use in the general Dutch population.


8

Driving under the influence of alcohol and other drugs

Logan BK, Mohr AL, Talpins SK.

Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.


doi: 10.1093/jat/bku050:

Szeremeta M, Ptaszynska-Sarosiek I, Wardaszkab Z, Niemcunowicz-Janica A.

Analysis of the prevalence of medicines and psychoactive substances among drivers in the material of the department of forensic medicine at the medical university of bialystok.

Adv Clin Exp Med 2014; 23: 245-51.

Epidemiology Acquistapace G, Rossi M, Garbi M, Cosci P, Canetta C, Manelli A, Ricevuti G.

Acute metformin intoxication: 2012 experience of Emergency Departement of Lodi, Italy.

Clin Chem Lab Med 2014; online early:

doi: 10.1515/cclm-2014-0208:

Anderson AR, Welles WL, Drew J, Orr MF.

The distribution and public health consequences of releases of chemicals intended for pool use in 17 states, 2001–2009.

J Environ Health 2014; 76: 10-5.

Bakhaidar M, Jan S, Farahat F, Attar A, Alsaywid B, Abuznadah W.

Pattern of drug overdose and chemical poisoning among patients attending an Emergency Department, Western Saudi Arabia.

J Community Health 2014; online early:

doi: 10.1007/s10900-014-9895-x:

Beauchamp GA, Ho ML, Yin S.

Variation in suicide occurrence by day and during major American holidays.

J Emerg Med 2014; 46: 776-81.

Binswanger IA, Blatchford PJ, Yamashita TE, Mueller S, Stern MF.

Trends in overdose deaths after release from state prison, 19992009.

Drug Alcohol Depend 2014; 140: e14.

Björnsson ES.

Epidemiology and risk factors for idiosyncratic drug-induced liver injury.

Semin Liver Dis 2014; 34: 115-22.

Bohnert AS, Walton MA, Ilgen MA, Cunningham RM, Barry K, Chermack S, Blow FC.

Overdose experiences among patients at an urban emer-gency department.


Bräuner EV, Nordsborg RB, Andersen ZJ, Tjønneland A, Loft S, Raaschou-Nielsen O.

Long-term exposure to low-level arsenic in drinking water and diabetes incidence: a prospective study of the Diet, Cancer and Health cohort.


doi: 10.1289/ehp.1408198:

Diallo T, Maïga D, Maiga A, Sangho H, Coulibaly B, Hami H, Mokthari A, Soulaymani R, Soulaymani A.

Fatal poisoning in Mali.

Med Sante Trop 2014; online early:

doi: 10.1684/mst.2014.0324:

Dinh MM, Bein KJ, Roncal S, Martiniuk ALC, Boufous S.

The impact of alcohol intoxication in patients admitted due to assault at an Australian major trauma centre: a trauma registry study from 1999 to 2009.

Emerg Med J 2014; 31: 390-3.

Hassanian-Moghaddam H, Nikfarjam A, Mirafzal A, Saberinia A, Nasehi AA, Masoumi AH, Memaryan N.

Methanol mass poisoning in Iran: role of case finding in outbreak management.

J Public Health (UK) 2014; online early:

doi: 10.1093/pubmed/fdu038:

Humblet O, Diaz-Ramirez LG, Balmes JR, Pinney SM, Hiatt RA.

Perfluoroalkyl chemicals and asthma among children 12–19 years of age: NHANES (1999–2008).


doi: 10.1289/ehp.1306606:

Iwersen-Bergmann S, Jungen H, Andresen-Streichert H, Müller A, Elakkary S, Püschel K, Heinemann A.

Intravenous methadone application as a serious risk factor for an overdose death: methadone-related fatalities in Hamburg from 2007 to 2012.

Int J Legal Med 2014; online early: doi: 10.1007/s00414-014-1017-x:

Kahn LG, Liu X, Rajovic B, Popovac D, Oberfield S, Graziano JH, Factor-Litvak P.

Blood lead concentration and thyroid function during pregnancy: results from the Yugoslavia Prospective Study of Environmental Lead Exposure.


doi: 10.1289/ehp.1307669:

Kumar J, Lind PM, Salihovic S, Van Bavel B, Ingelsson E, Lind L.

Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly Swedish people: the PIVUS cohort.


doi: 10.1289/ehp.1307613:

Le Lait M-C, Martinez EM, Severtson SG, Lavery SA, Bucher-Bartelson B, Dart RC.

Assessment of prescription opioid intentional exposures across the rural-urban continuum in the United States using both population and drug availability rates.

Pharmacoepidemiol Drug Saf 2014; online early:

doi: 10.1002/pds.3653:

Mendoza A, Rodríguez-Gil JL, González-Alonso S, Mastroianni N, López de Alda M, Barceló D, Valcárcel Y.

Drugs of abuse and benzodiazepines in the Madrid Region (Central Spain): seasonal variation in river waters, occurrence in tap water and potential environmental and human risk.

Environ Int 2014; 70C: 76-87.

Mercado-Crespo MC, Sumner SA, Spelke MB, Sugerman DE, Stanley C, EIS Officer CDC.

Notes from the field: increase in fentanyl-related overdose deaths – Rhode Island, November 2013-March 2014.

MMWR Morb Mortal Wkly Rep 2014; 63: 531.

9

Epidemiology

Nalliah RP, Anderson IM, Lee MK, Rampa S, Allareddy V, Allareddy V.

Children in the United States make close to 200,000 emergency department visits due to poisoning each year.

Pediatr Emerg Care 2014; 30: 453-7.

Newman NC, Ryan PH, Huang B, Beck AF, Sauers HS, Kahn RS.

Traffic-related air pollution and asthma hospital readmission in children: a longitudinal cohort study.

J Pediatr 2014; 164: 1396-402.

Palacios N, Fitzgerald K, Roberts AL, Hart JE, Weisskopf MG, Schwarzschild MA, Ascherio A, Laden F.

A prospective analysis of airborne metal exposures and risk of Parkinson disease in the Nurses Health Study cohort.


doi: 10.1289/ehp.1307218:

Pereira G, Bell ML, Lee HJ, Koutrakis P, Belanger K.

Sources of fine particulate matter and risk of preterm birth in Connecticut, 2000–2006: a longitudinal study.


doi: 10.1289/ehp.1307741:

Rappazzo KM, Daniels JL, Messer LC, Poole C, Lobdell DT.

Exposure to fine particulate matter during pregnancy and risk of preterm birth among women in New Jersey, Ohio, and Pennsylvania, 2000-2005.


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Stevens L.

My campaign to promote poison prevention awareness in the community.

Drug Topics 2014; MAY:

Vakkalanka P, Rushton WF, Hardison LS, Bishop MC, Haverstick DM, Holstege CP.

Evaluation of the initiation of urine drug screens intended for use in transfer patients.

Am J Emerg Med 2014; online early:

doi: 10.1016/j.ajem.2014.06.011:

Watson R.

Heroin and cannabis use is declining but new drugs show increase, says EU report.

Br Med J 2014; 348: g3647.

Yamazaki S, Shima M, Nakadate T, Ohara T, Omori T, Ono M, Sato T, Nitta H.

Association between traffic-related air pollution and development of asthma in school children: cohort study in Japan.

J Expos Sci Environ Epidemiol 2014; 24: 372-9.

Foreign body ingestion Pagenhardt JA, Larrabee H, Davidov DM, Davis SM.

Pediatric visits to United States emergency departments for foreign body ingestions.

Acad Emerg Med 2014; 21: S45-S46.

Forensic toxicology Barnes AJ, Young S, Spinelli E, Martin TM, Klette KL, Huestis MA.

Evaluation of a homogenous enzyme immunoassay for the detection of synthetic cannabinoids in urine.


Bezemer KDB, Smink BE, van Maanen R, Verschraagen M, de Gier JJ.



Gilbert JD, Musgrave IF, Hoban C, Byard RW.

Lethal hepatocellular necrosis associated with herbal polypharmacy in a patient with chronic hepatitis B infection.


Horvat V.

Toxicology in forensic medicine.

Biochem Med (Zagreb) 2014; 24: A3.

Krabseth H, Mørland J, Høiseth G.

Assistance of ethyl glucuronide and ethyl sulfate in the interpretation of postmortem ethanol findings.

Int J Legal Med 2014; online early: doi: 10.1007/s00414-014-1031-z:

Palmiere C, Werner D.

Post-mortem beta-hydroxybutyrate determination in synovial fluid.

Forensic Sci Int 2014; online early:

doi: 10.1016/j.forsciint.2014.04.034:

Poon S, Gareri J, Walasek P, Koren G.

Norcocaine in human hair as a biomarker of heavy cocaine use in a high risk population.


Sundström M, Jones AW, Ojanperä I.

Utility of urinary ethyl glucuronide analysis in post-mortem toxicology when investigating alcohol-related deaths.

Forensic Sci Int 2014; 241C: 178-82.

Wunder C, Kauert GF, Toennes SW.

Factors leading to the degradation/loss of insulin in postmortem blood samples.


Genotoxicity Chinde S, Kumari M, Devi KR, Murty US, Rahman MF, Kumari SI, Mahboob M, Grover P.

Assessment of genotoxic effects of lead in occupationally exposed workers.

Environ Sci Pollut Res 2014; online early:

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Da Silva FR, Kvitko K, Rohr P, Abreu MB, Thiesen FV, da Silva J.

Genotoxic assessment in tobacco farmers at different crop times.

Sci Total Environ 2014; 490C: 334-41.

Joshi D, Kumar MD, Kumar SA, Sangeeta S.

Reversal of methylmercury-induced oxidative stress, lipid peroxidation, and DNA damage by the treatment of N-acetyl cysteine: a protective approach.

J Environ Pathol Toxicol Oncol 2014; 33: 167-82.

Mesic A, Nefic H.

Assessment of the genotoxicity and cytotoxicity in environmentally exposed human populations to heavy metals using the cytokinesis-block micronucleus cytome assay.

Environ Toxicol 2014; online early:

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Hepatotoxicity Björnsson ES.


Semin Liver Dis 2014; 34: 115-22.

Chen M, Borlak J, Tong W.

Predicting idiosyncratic drug-induced liver injury – Some recent advances.

Expert Rev Gastroenterol Hepatol 2014; online early: doi: 10.1586/17474124.2014.922871:

Chen M, Tung C-W, Shi Q, Guo L, Shi L, Fang H, Borlak J, Tong W.

A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model. Arch Toxicol 2014; 88: 1439-49.

Frass M, Zagorchev P, Yurukova V, Wulkersdorfer B, Thieves K, Zedtwitz-Liebenstein K, Bursch W, Kaye AD.

Two cases of fulminant hepatic failure from Amanita phalloides poisoning treated additively by homeopathy.

Ochsner J 2014; 14: 252-8.

Gilbert JD, Musgrave IF, Hoban C, Byard RW. Lethal hepatocellular necrosis associated with herbal polypharmacy in a patient with chronic hepatitis B infection.


Hampton T.

Mouse model may help screen drugs for liver toxicity.

JAMA 2014; 311: 2162.

Hayashi M, Kanda T, Nakamura M, Miyamura T, Yasui S, Nakamoto S, Wu S, Arai M, Imazeki F, Yokosuka O.

Acute liver injury in a patient with alcohol dependence: a case resembling autoimmune hepatitis or drug-induced liver injury.

Case Rep Gastroenterol 2014; 8: 129-33.

Hayashi PH, Fontana RJ.

Clinical features, diagnosis, and natural history of drug-induced liver injury.

Semin Liver Dis 2014; 34: 134-44.

Langrand J, Regnault H, Cachet X, Bouzidi C, Villa AF, Serfaty L, Garnier R, Michel S.

Toxic hepatitis induced by a herbal medicine: Tinospora crispa.

Phytomedicine 2014; 21: 1120-3.

Maruyama Y, Yoshizawa K, Tsuruta F, Maruyama M, Fujimori K, Shigeno T, Fukushima M, Uehara T, Morita S, Joshita S, Umemura T, Tanaka E.

A case of repeated liver injury induced by different herbal medicines containing the same components.

Acta Hepatol Jpn 2014; 55: 214-20.

Navarro VJ, Lucena MI.

Hepatotoxicity induced by herbal and dietary supplements.

Semin Liver Dis 2014; 34: 172-93.

Strober BE.

Methotrexate-induced liver toxicity: replacing the liver biopsy.

JAMA Dermatol 2014; online early:

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Tangchaivang N.

Acute hepatotoxicity: a complication of chaparral ingestion. J Gen Intern Med 2014; 29: S297.

Wang K.

Molecular mechanisms of liver injury: apoptosis or necrosis.

Exp Toxicol Pathol 2014; online early:

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Willey JZ, Tolchin BD.

Liver transplant for intentional acetaminophen overdose and hepatic encephalopathy: a conflict between beneficence and justice.

Continuum (Minneap Minn) 2014; 20: 681-5.

Williams DP.

Modeling hepatic drug metabolism and toxicity: where are we heading?

Future Med Chem 2014; 6: 725-7.

Xie Y, Mcgill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H.

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Toxicol Appl Pharmacol 2014; online early:

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Inhalation toxicity Anon.

Pulmonary fibrosis associated with aluminum trihydrate (corian) dust.

N Engl J Med 2014; 370: 2154-7.

Chibishev AA, Simonovska N, Bozinovska C, Pereska Z, Smokovski I, Glasnovic M.

Respiratory complications from acute corrosive poisonings in adults.

Mater Sociomed 2014; 26: 80-3.

Hoppin JA, Umbach DM, Long S, Rinsky JL, Henneberger PK, Salo PM, Zeldin DC, London SJ, Alavanja MCR, Blair A, Beane Freeman LE, Sandler DP.

Respiratory disease in United States farmers.

Occup Environ Med 2014; 71: 484-91.

Imbert L, Boucher A, Delhome G, Cueto T, Boudinaud M, Maublanc J, Dulaurent S, Descotes J, Lachâtre G, Gaulier J-M.


J Anal Toxicol 2014; online early: doi: 10.1093/jat/bku052:

Mechanisms of toxicity Fu PP, Xia Q, Hwang H-M, Ray PC, Yu H.

Mechanisms of nanotoxicity: generation of reactive oxygen species.

J Food Drug Anal 2014; 22: 64-75.

LoPachin RM, Gavin T.

Molecular mechanisms of aldehyde toxicity: a chemical perspective.

Chem Res Toxicol 2014; online early:

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Narasimhan M, Riar AK, Rathinam ML, Vedpathak D, Henderson G, Mahimainathan L.

Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neuro-toxicity.

Toxicol Lett 2014; 228: 179-91.

11

Mechanisms of toxicity

Senthilkumaran S, Menezes RG, Meenakshisundaram R, Thirumalaikolundusubramanian P.

Carbon monoxide poisoning and intracardiac thrombus formation: additional mechanisms.

Hum Exp Toxicol 2014; online early:

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Medication errors Geyer HL, Herskovitz S, Slamovits TL, Schaumburg HH.

Optochiasmatic and peripheral neuropathy due to ethambutol overtreatment.

J Neuro-Ophthalmol 2014; online early:

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Lövborg H, Holmlund M, Hägg S.

Medication errors related to transdermal opioid patches: lessons from a regional incident reporting system.

BMC Pharmacol Toxicol 2014; 15: 31.

Nephrotoxicity Luciano RL, Castano E, Moeckel G, Perazella MA.

Bile acid nephropathy in a bodybuilder abusing an anabolic androgenic steroid.

Am J Kidney Dis 2014; online early:

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May J, Carson KR, Butler S, Liu W, Bartlett NL, Wagner-Johnston ND.

High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis.

Leuk Lymphoma 2014; 55: 1345-9.

Morgan KP, Snavely AC, Wind LS, Buie LW, Grilley-Olson J, Walko CM, Weiss J.

Rates of renal toxicity in cancer patients receiving cisplatin with and without mannitol.

Ann Pharmacother 2014; 48: 863-9.

Sklienka P, Neiser J, Ševcik M, Dvoracek I, Samlík J, Jonszta T, Dedek V, Kubišová MM, Tomanová R, Streitová D.

Successful kidney transplant from methanol-intoxicated donors.

Prog Transplant 2014; 24: 199-205.

Neurotoxicity Brust JC.

Neurologic complications of illicit drug abuse.


Damasio J, Garrido C, Moreira I, Neves S, Freitas J.

Chorea as an acute manifestation of carbon monoxide poisoning.

Mov Disord 2014; 29: S193.

Deeb W, Cachia D, Quinn C, Salameh J.

Peripheral neuropathy after hair dye exposure: a case report.

J Clin Neuromuscul Dis 2014; 15: 161-3.

Doe A, Chaunu MP, Orquevaux P, Regrain E, Tranchant C, Bakchine S.

Acute methanol intoxication: a rare cause of axial Parkinsonism.

Mov Disord 2014; 29: S107.

Feldman V.



Gelinas J, Allukian M, Jr.



Geyer HL, Herskovitz S, Slamovits TL, Schaumburg HH.



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Goldstein DA, Saltmiras DA.


Lancet Neurol 2014; 13: 645.

Grandjean P, Landrigan PJ.

Neurodevelopmental toxicity: still more questions than answers - authors' response.


Guimarãúes D, Santos JP, Carvalho ML, Diniz MS, House B, Miller VM.

Analytical evidence of heterogeneous lead accumulation in the hypothalamic defence area and nucleus tractus solitarius.

Neurotoxicology 2014; 44: 91-7.

Heitmiller DR.

Serotonin syndrome: a concise review of a toxic state.

R I Med J (2013) 2014; 96: 33-5.

Kotchev NP, George C.

Sub-acute presentation of neuroleptic malignant syndrome in a nursing home.

J Am Geriatr Soc 2014; 62: S56.

Landais A.

Severe memory impairment following acute morphine intoxication.

J Neurol Sci 2014; online early:

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Li H, Lan Y.

Re: Regarding letter by MacGregor and Du concerning "Vanadium exposure-induced neurobehavioral alterations among Chinese workers".


doi: 10.1016/j.neuro.2014.05.008:

Lucchini RG, Guazzetti S, Zoni S, Benedetti C, Fedrighi C, Peli M, Donna F, Bontempi E, Borgese L, Micheletti S, Ferri R, Marchetti S, Smith DR.

Neurofunctional dopaminergic impairment in elderly after lifetime exposure to manganese.


doi: 10.1016/j.neuro.2014.05.006:

MacGregor JA, Du H.

Re: vanadium exposure-induced neurobehavioral alterations among Chinese workers Li et al. (2013).


doi: 10.1016/j.neuro.2014.05.007:

Meijer M, Dingemans MML, van den Berg M, Westerink RHS.

Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides.

Toxicol Sci 2014; online early:

doi: 10.1093/toxsci/kfu110:

12

Neurotoxicity

Mihailescu R, Bajenaru O, Copaciu E, Pop C, Ene A.

Cerebral imaging findings and neurologic outcome of methanol poisoning.

Eur J Neurol 2014; 21: 576.


Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity.

Toxicol Lett 2014; 228: 179-91.

Noble JM, Weimer LH.

Neurologic complications of alcoholism.


Park E-J, Min Y-G, Kim G-W, Cho J, Maeng W, Choi S-C.

Pathophysiology of brain injuries in acute carbon monoxide poisoning: a novel hypothesis.

Med Hypotheses 2014; 83: 186-9.

Rao JVB, Vengamma B, Naveen T, Naveen V.

Lead encephalopathy in adults.

J Neurosci Rural Pract 2014; 5: 161-3.

Sawamoto K, Loro E, Krajacic P, Gaspari R, Khurana T, Bird SB.

Timecourse of neuromuscular junction failure after acute parathion poisoning.

Acad Emerg Med 2014; 21: S180.

Selikhova MV, Tripolity E, Sanotsky Y, Matvienko Y, Staneska H, Fedorishin L, Komnatska I, Lees AJ.

Whispering dysarthria – A diagnostic hint for chronic manganese poisoning.

Mov Disord 2014; 29: S127-S128.

Tyler CR, Allan AM.

The effects of arsenic exposure on neurological and cognitive dysfunction in human and rodent studies: a review.

Curr Environ Health Rep 2014; 1: 132-47.

Wendroff AP.



Occupational toxicology Aggarwal BD.

Lactate dehydrogenase as a biomarker for silica exposure-induced toxicity in agate workers.


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Ahrens W, Merletti F, Mirabelli D.

Biliary tract cancer in male printers and typesetters in the European rare cancer case-control study.


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Barber CM, Burton CM, Hendrick DJ, Pickering CA, Robertson AS, Robertson W, Burge PS.

Hypersensitivity pneumonitis in workers exposed to metalworking fluids.

Am J Ind Med 2014; online early:

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Beard JD, Umbach DM, Hoppin JA, Richards M, Alavanja MCR, Blair A, Sandler DP, Kamel F.

Pesticide exposure and depression among male private pesticide applicators in the agricultural health study.

Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307450:

Bian L-Q, Mao L, Shi J, Bi Y.

Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneumoconiosis: a case-control study.


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Chalupka S.

Reducing workplace exposure to 1-bromopropane.

Workplace Health Saf 2014; 62: 128.

Chinde S, Kumari M, Devi KR, Murty US, Rahman MF, Kumari SI, Mahboob M, Grover P.



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Donoghue AM, Coffey PS.

Health risk assessments for alumina refineries.

J Occup Environ Med 2014; 56: S18-S22.

Donoghue AM, Frisch N, Olney D.

Bauxite mining and alumina refining: process description and occupational health risks.


Egilman D.

Workers and consumers should not be exposed to chemicals that have not been tested for toxicity.


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Gaum PM, Esser A, Schettgen T, Gube M, Kraus T, Lang J.

Prevalence and incidence rates of mental syndromes after occupational exposure to polychlorinated biphenyls.

Int J Hyg Environ Health 2014; online early:

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Ghosh T, Gangopadhyay S, Das B.

Prevalence of respiratory symptoms and disorders among rice mill workers in India.

Environ Health Prev Med 2014; 19: 226-33.

Gibbs GW, Labrèche F.

Cancer risks in aluminum reduction plant workers: a review.


Hoppin JA, Umbach DM, Long S, Rinsky JL, Henneberger PK, Salo PM, Zeldin DC, London SJ, Alavanja MCR, Blair A, Beane Freeman LE, Sandler DP.

Respiratory disease in United States farmers.

Occup Environ Med 2014; 71: 484-91.

13

Occupational toxicology

Huang P, Ren X, Huang Z, Yang X, Hong W, Zhang Y, Zhang H, Liu W, Huang H, Huang X, Wu D, Yang L, Tang H, Zhou L, Li X, Liu J.

Serum proteomic analysis reveals potential serum bio-markers for occupational medicamentosa-like dermatitis caused by trichloroethylene.

Toxicol Lett 2014; 229: 101-10.

Ibrahim KS, Amer NM, El-dossuky EA, Emara AM, El-Fattah AESM, Shahy EM.



Kafferlein HU, Broding HC, Bunger J, Jettkant B, Koslitz S, Lehnert M, Marek EM, Blaszkewicz M, Monse C, Weiss T, Bruning T.

Human exposure to airborne aniline and formation of methemoglobin: a contribution to occupational exposure limits.

Arch Toxicol 2014; 88: 1419-26.

Kasperczyk S, Dobrakowski M, Kasperczyk A, Zalejska-Fiolka J, Pawlas N, Kapka-Skrzypczak L, Birkner E.

Effect of treatment with N-acetylcysteine on non-enzymatic antioxidant reserves and lipid peroxidation in workers exposed to lead.

Ann Agric Environ Med 2014; 21: 272-7.

Kolena B, Petrovicova I, Pilka T, Pucherova Z, Munk M, Matula B, Vankova V, Petlus P, Jenisova Z, Rozova Z, Wimmerova S, Trnovec T.

Phthalate exposure and health-related outcomes in specific types of work environment.


Kongerud J, Søyseth V.

Respiratory disorders in aluminum smelter workers.


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JAMA 2014; 311: 2057.

Kvande H, Drabløs PA.

The aluminum smelting process and innovative alternative technologies.


Laborde-Castérot H, Laurier D, Caër-Lorho S, Etard C, Acker A, Rage E.

Chest X-ray screening examinations among French uranium miners: exposure estimation and impact on radon-associated lung cancer risk.


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Li H, Lan Y.

Re: Regarding letter by MacGregor and Du concerning "Vanadium exposure-induced neurobehavioral alterations among Chinese workers".


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Lidsky TI.

Is the aluminum hypothesis dead?


Lucas CD, Amft N, Reid PT.

Systemic lupus erythematosus complicating simple silicosis.

Occup Med (Oxf) 2014; online early: doi: 10.1093/occmed/kqu060:

MacGregor JA, Du H.

Re: vanadium exposure-induced neurobehavioral alterations among Chinese workers Li et al. (2013).


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Martin SC, Larivière C.

Community health risk assessment of primary aluminum smelter emissions. J Occup Environ Med 2014; 56: S33-S39.

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Spears DR, McNeil C, Warnock E, Trapp J, Oyinloye O, Whitehurst V, Decker KC, Chapman S, Campbell M, Meechan P.

Predicting temporal trends in total absenteeism rates for civil service employees of a federal public health agency. J Occup Environ Med 2014; 56: 632-8.

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Yoo S-J, Park S-J, Kim B-S, Lee K, Lim H-S, Kim J-S, Kim I-S. Airborne nicotine concentrations in the workplaces of tobacco farmers.

J Prev Med Public Health 2014; 47: 144-9.

Paediatric toxicology Anon.

Nicotine replacement products: poisoning in children.

Prescrire Int 2014; 23: 126-8.

Ahmed S, Moore SE, Kippler M, Gardner R, Hawlader MDH, Wagatsuma Y, Raqib R, Vahter M.

Arsenic exposure and cell-mediated immunity in pre-school children in rural Bangladesh.



Akkus C, Ozdenerol E.

Exploring childhood lead exposure through GIS: a review of the recent literature.


Allegaert K, van den Anker JN.

Adverse drug reactions in neonates and infants: a population tailored approach is needed.

Br J Clin Pharmacol 2014; online early:

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Aydinok Y, Kattamis A, Viprakasit V.

Current approach to iron chelation in children.

Br J Haematol 2014; 165: 745-55.

Buck D, Kreeger R, Spaeth J.

Case discussion and root cause analysis: bupivacaine overdose in an infant leading to ventricular tachycardia. Anesth Analg 2014; 119: 137-40.

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Chiao S, Zuo Z.

A double-edged sword: volatile anesthetic effects on the neonatal brain.

Brain Sci 2014; 4: 273-94.

Correa JA, Fallon SC, Cruz AT, Grawe GH, Vu PV, Rubalcava DM, Kaziny B, Naik-Mathuria BJ, Brandt ML.

Management of pediatric snake bites: are we doing too much?

J Pediatr Surg 2014; 49: 1009-15.

Forrester MB.

Characteristics of hand sanitizer ingestions by adolescents reported to poison centers.

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Frémont D, Berleur M-P, Mégarbane B.

Loading dose of fomepizole is safe in children with presumed toxic alcohol exposure - a case series.

Basic Clin Pharmacol Toxicol 2014; online early: doi: 10.1111/bcpt.12276:

Guney M, Nguyen A, Zagury GJ.

Estimating children's exposure to toxic elements in contaminated toys and children's jewelry via saliva mobilization.

J Environ Sci Health A Tox Hazard Subst Environ Eng 2014; 49: 1218-27.

Hansen R.

Hyponatraemic seizure in a 6-month-old infant due to water intoxication.

J Paediatr Child Health 2014; online early:

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Heard K, Bui A, Mlynarchek SL, Green JL, Bond GR, Clark RF, Kozer E, Koff RS, Dart RC.

Toxicity from repeated doses of acetaminophen in children: assessment of cause.

Am J Ther 2014; 21: 174-83.

Hsu W-F, Wang C-C, Chen S-J, Lu Y-C, Hu C-F, Huang S-W, Wang D-S, Hsu Y-J, Fan H-C.

Water intoxication induced status epilepticus in two children.

J Med Sci Taiwan 2014; 34: 77-80.

Humblet O, Diaz-Ramirez LG, Balmes JR, Pinney SM, Hiatt RA.



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Lucas BR, Latimer J, Pinto RZ, Ferreira ML, Doney R, Lau M, Jones T, Dries D, Elliott EJ.

Gross motor deficits in children prenatally exposed to alcohol: a meta-analysis.

Pediatrics 2014; 134: e192-e209.

Mosquera RA, McDonald M, Samuels C.

Aspiration pneumonitis caused by polyethylene glycol-electrolyte solution treated with conservative management.

Case Rep Pediatr 2014; 2014: 872634.

Nalliah RP, Anderson IM, Lee MK, Rampa S, Allareddy V, Allareddy V.

Children in the United States make close to 200,000 emergency department visits due to poisoning each year.

Pediatr Emerg Care 2014; 30: 453-7.

Newman NC, Ryan PH, Huang B, Beck AF, Sauers HS, Kahn RS. Traffic-related air pollution and asthma hospital readmission in children: a longitudinal cohort study. J Pediatr 2014; 164: 1396-402. Nye MD, Fry RC, Hoyo C, Murphy SK. Investigating epigenetic effects of prenatal exposure to toxic metals in newborns: challenges and benefits. Med Epigenet 2014; 2: 53-9. Pagenhardt JA, Larrabee H, Davidov DM, Davis SM. Pediatric visits to United States emergency departments for foreign body ingestions. Acad Emerg Med 2014; 21: S45-S46. Poulos SG, Richie WD, Bailey RK, Lee A, dela Peña I, Sanberg PR, Borlongan CV. The potential of neural stem cell transplantation for the treatment of fetal alcohol spectrum disorder. Prog Neuropsychopharmacol Biol Psychiatry 2014; 54C: 149-56. Prakash V, Krishnamurthy S, Mahadevan S, Bethou A, Barathi SD. Infective endocarditis and septic pulmonary embolism following scorpion sting envenoming in an 11-year-old child. Paediatr Int Child Health 2014; 34: 145-7. Rakotomavo F, Andriamasy C, Rasamoelina N, Raveloson N. Datura stramonium intoxication in two children. Pediatr Int 2014; 56: e14-e16. Sivathanu S, Sampath S, David HS, Rajavelu KK. Myristicin and phenytoin toxicity in an infant. BMJ Case Rep 2014; doi: 10.1136/bcr-2013-203000: Smirk CL, Bowman E, Doyle LW, Kamlin O. Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment. Acta Paediatr 2014; 103: 601-4. Stevens L. My campaign to promote poison prevention awareness in the community. Drug Topics 2014; MAY: Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ. Associations of children's lung function with ambient air pollution: Joint effects of regional and near-roadway pollutants. Thorax 2014; 69: 540-7. Ward MH, Colt JS, Deziel NC, Whitehead TP, Reynolds P, Gunier RB, Nishioka M, Dahl GV, Rappaport SM, Buffler PA, Metayer C. Residential levels of polybrominated diphenyl ethers and risk of childhood acute lymphoblastic leukemia in California. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307602: Yamazaki S, Shima M, Nakadate T, Ohara T, Omori T, Ono M, Sato T, Nitta H. Association between traffic-related air pollution and devel-opment of asthma in school children: cohort study in Japan. J Expos Sci Environ Epidemiol 2014; 24: 372-9. Zaki SA, Khanage YG. Baclofen induced coma in an infant. J Pediatr Neurosci 2014; 9: 86-8.

15

Paediatric toxicology

Zarek J, Koren G.

The fetal safety of statins: a systematic review and meta-analysis.

J Obstet Gynaecol Can 2014; 36: 506-9.

Poisons information and poison

information centres Cheema N.

A fellow's perspective on the threatened closure of the Illinois poison center.

J Med Toxicol 2014; online early: doi: 10.1007/s13181-014-0407-2:

Polymorphisms Basu N, Goodrich JM, Head J.

Ecogenetics of mercury: from genetic polymorphisms and epigenetics to risk assessment and decision-making.

Environ Toxicol Chem 2014; 33: 1248-58.

Bian L-Q, Mao L, Shi J, Bi Y.

Polymorphisms in cyclooxygenase-2 gene and risk of developing coal workers' pneumoconiosis: a case-control study.


doi: 10.1002/ajim.22335:

Psychiatric aspects Beard JD, Umbach DM, Hoppin JA, Richards M, Alavanja MCR, Blair A, Sandler DP, Kamel F.

Pesticide exposure and depression among male private pesticide applicators in the agricultural health study.


doi: 10.1289/ehp.1307450:

Gaum PM, Esser A, Schettgen T, Gube M, Kraus T, Lang J.



doi: 10.1016/j.ijheh.2014.06.001:

Kaprinis S, Parlapani E, Raikos N, Goulas A, Karpouza V.

Psychotic episode associated with sertraline and drug-related delirium: a case report.


Litjens RP, Brunt TM, Alderliefste G-J, Westerink RH.

Hallucinogen persisting perception disorder and the serotonergic system: A comprehensive review including new MDMA-related clinical cases.

Eur Neuropsychopharmacol 2014; online early:

doi: 10.1016/j.euroneuro.2014.05.008:

Tang Y, Martin NL, Cotes RO.

Cocaine-induced psychotic disorders: presentation, mechanism, and management.

J Dual Diagn 2014; 10: 98-105.

Reprotoxicity Cassault-Meyer E, Gress S, Seralini GE, Galeraud-Denis I.

An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality.

Environ Toxicol Pharmacol 2014; 38: 131-40.

Enkhmaa D, Warburton N, Javzandulam B, Uyanga J, Khishigsuren Y, Lodoysamba S, Enkhtur S, Warburton D.

Seasonal ambient air pollution correlates strongly with spontaneous abortion in Mongolia.

BMC Pregnancy Childbirth 2014; 14: 146.

Ferguson KK, Peterson KE, Lee JM, Mercado-García A, Goldenberg CB, Téllez-Rojo MM, Meeker JD.

Prenatal and peripubertal phthalates and bisphenol-A in relation to sex hormones and puberty in boys.


doi: 10.1016/j.reprotox.2014.06.002:

Friedrich MJ.

Spontaneous abortions in mongolia linked to high air pollutant levels.

JAMA 2014; 311: 2372.

Galimova EF, Amirova ZK, Galimov SN.

Dioxins in the semen of men with infertility.


doi: 10.1007/s11356-014-3109-z:

Jamkhande PG, Chintawar KD, Chandak PG.

Teratogenicity: a mechanism based short review on common teratogenic agents.

Asian Pac J Trop Dis 2014; 4: 421-32.

Jeng HA.

Exposure to endocrine disrupting chemicals and male reproductive health.

Front Public Health 2014; online early:

doi: 10.3389/fpubh.2014.00055:

Kay VR, Bloom MS, Foster WG.

Reproductive and developmental effects of phthalate diesters in males.


Messinger H, Bär A.

Subchronic toxicity, toxicity to reproduction and prenatal developmental toxicity of vinyl laurate.

Regul Toxicol Pharmacol 2014; online early:

doi: 10.1016/j.yrtph.2014.06.015:

Nieuwenhuijsen MJ, Basagaña X, Dadvand P, Martinez D, Cirach M, Beelen R, Jacquemin B.

Air pollution and human fertility rates.

Environ Int 2014; 70: 9-14.

Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA.

Bisphenol A and reproductive health: update of experimental and human evidence, 2007-2013.


doi: 10.1289/ehp.1307728:

Welch KD, Lee ST, Panter KE, Gardner DR, Knoppel EL, Green BT, Hammond CK, Hammond ZJ, Pfister JA.

Studies on the teratogenicity of anabasine in a rat model.

Toxicon 2014; 87: 32-7.

Risk assessment Anon.

What is risk assessment in occupational health?

J Occup Environ Med 2014; 56: e44.

Connor K, Magee B.

A quantitative assessment of risks of heavy metal residues in laundered shop towels and their use by workers.


doi: 10.1016/j.yrtph.2014.06.020:

16

Risk assessment

Getaneh Z, Mekonen S, Ambelu A. Exposure and health risk assessment of lead in communities of Jimma town, southwestern Ethiopia. Bull Environ Contam Toxicol 2014; online early: doi: 10.1007/s00128-014-1293-7:

Guth K, Riviere JE, Brooks JD, Dammann M, Fabian E, van Ravenzwaay B, Schäfer-Korting M, Landsiedel R. In silico models to predict dermal absorption from complex agrochemical formulations. SAR QSAR Environ Res 2014; online early: doi: 10.1080/1062936X.2014.919358: Mahmood A, Malik RN, Li J, Zhang G. Human health risk assessment and dietary intake of organochlorine pesticides through air, soil and food crops (wheat and rice) along two tributaries of river Chenab, Pakistan. Food Chem Toxicol 2014; 71: 17-25.

Martin SC, Larivière C. Community health risk assessment of primary aluminum smelter emissions. J Occup Environ Med 2014; 56: S33-S39. Tvermoes BE, Banducci AM, Devlin KD, Kerger BD, Abramson MM, Bebenek IG, Monnot AD. Screening level health risk assessment of selected metals in apple juice sold in the United States. Food Chem Toxicol 2014; 71: 42-50.

Suicide Beauchamp GA, Ho ML, Yin S. Variation in suicide occurrence by day and during major American holidays. J Emerg Med 2014; 46: 776-81.

Chang S-S, Chen Y-Y, Yip PSF, Lee WJ, Hagihara A, Gunnell D. Regional changes in charcoal-burning suicide rates in East/Southeast Asia from 1995 to 2011: a time trend analysis. PLoS Med 2014; 11: e1001622. Coskun AS, Atalay C, Dagli C, Dogan N, Kürsad H. A suicide attempt using zinc phosphide (a case study). J Clin Anal Med 2014; 5: 65-6. Nishiyori Y, Nishida M, Shioda K, Suda S, Kato S. Unilateral hippocampal infarction associated with an attempted suicide: a case report. J Med Case Reports 2014; 8: 219. Silva AC, de Oliveira Ribeiro NP, de Mello Schier AR, Pereira VM, Vilarim MM, Pessoa TM, Arias-Carrion O, Machado S, Nardi AE. Caffeine and suicide: a systematic review. CNS Neurol Disord Drug Targets 2014; online early: doi: 10.2174/1871527313666140612123656:

Singhal A, Ross J, Seminog O, Hawton K, Goldacre MJ. Risk of self-harm and suicide in people with specific psychiatric and physical disorders: comparisons between disorders using English national record linkage. J R Soc Med 2014; 107: 194-204.

MANAGEMENT General Henry NL. Endocrine therapy toxicity: management options. Am Soc Clin Oncol Educ Book 2014; 34: e25-e30.

Mahendrakar K, Venkategowda PM, Rao SM, Mutkule DP.

Glyphosate surfactant herbicide poisoning and management.

Indian J Crit Care Med 2014; 18: 328-30.

McEvoy MD, Hand WR, Stoll WD, Furse CM, Nietert PJ.

Adherence to guidelines for the management of local anesthetic systemic toxicity is improved by an electronic decision support tool and designated "reader".

Reg Anesth Pain Med 2014; 39: 299-305.

Mosquera RA, McDonald M, Samuels C.


Case Rep Pediatr 2014; 2014: 872634.

Nakae H, Hattori T, Igarashi T, Okuyama M, Tajimi K.

Removal of toxic substances by a selective membrane plasma separator.

Ther Apheresis Dial 2014; 18: 265-71.

Omar HR, Sprenker C, Karlnoski R, Mangar D, Camporesi EM.

The use of isoproterenol and phenytoin to reverse torsade de pointes.

Am J Emerg Med 2014; 32: 683.

Palatnick W, Jelic T.

Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity.

Emerg Med Pract 2014; 16: 1-19.

Rafati-Rahimzadeh M, Rafati-Rahimzadeh M, Kazemi S, Moghadamnia AA.

Current approaches of the management of mercury poi-soning: need of the hour.

Daru 2014; 22: 46.

Shahidi Bonjar L.

Design of a new therapy to treat snake envenomation.

Drug Des Devel Ther 2014; 8: 819-25.

Smirk CL, Bowman E, Doyle LW, Kamlin O.

Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment.

Acta Paediatr 2014; 103: 601-4.

Sun L, Li G, Yan P, Liu Y, Li G, Wei L-Q.

Clinical management of organophosphate poisoning in pregnancy.


doi: 10.1016/j.ajem.2014.05.057:

Thakrar R, Shulman R, Bellingan G, Singer M.

Management of a mixed overdose of calcium channel blockers, -blockers and statins.

BMJ Case Rep 2014; doi: 10.1136/bcr-2014-204732:

Wang X, Zhang Y, Ni L, You C, Ye C, Jiang R, Liu L, Liu J, Han C.


Burns 2014; online early:

doi: 10.1016/j.burns.2014.04.009:

Antidotes Suryanarayan D, Schulman S.

Potential antidotes for reversal of old and new oral anticoagulants.

Thromb Res 2014; 133 Suppl 2: S158-S166.

17

Antidotes

Yardehnavi N, Behdani M, Pooshang BK, Mahmoodzadeh A, Khanahmad H, Shahbazzadeh D, Habibi-Anbouhi M, Ghassabeh GH, Muyldermans S.

A camelid antibody candidate for development of a ther-apeutic agent against Hemiscorpius lepturus envenomation.

FASEB J 2014; online early: doi: 10.1096/fj.13-247478:

Acetylcysteine Kasperczyk S, Dobrakowski M, Kasperczyk A, Zalejska-Fiolka J, Pawlas N, Kapka-Skrzypczak L, Birkner E.



Koppen A, Van Riel A, de Vries I, Meulenbelt J.

Recommendations for the paracetamol treatment nomogram and side effects of N-acetylcysteine.

Neth J Med 2014; 72: 251-7.

Antivenom Bush SP, Mooy GG, Phan TH.

Catastrophic acute ischemic stroke after Crotalidae polyvalent immune Fab (ovine)-treated rattlesnake envenomation.

Wilderness Environ Med 2014; 25: 198-203.

Chelating agents Aydinok Y, Kattamis A, Viprakasit V.


Br J Haematol 2014; 165: 745-55.

Cao Y, Skaug MA, Andersen O, Aaseth J.

Chelation therapy in intoxications with mercury, lead and copper.

J Trace Elem Med Biol 2014; online early:

doi: 10.1016/j.jtemb.2014.04.010:

Tegoni M, Valensin D, Toso L, Remelli M.

Copper chelators: chemical properties and biomedical applications.

Curr Med Chem 2014; online early PM:24934357:

Fomepizole Frémont D, Berleur M-P, Mégarbane B.

Loading dose of fomepizole is safe in children with presumed toxic alcohol exposure – A case series.

Basic Clin Pharmacol Toxicol 2014; online early:

doi: 10.1111/bcpt.12276:

Hydroxylamine Lo R, Ganguly B.

Can hydroxylamine be a more potent nucleophile for the reactivation of tabun-inhibited AChE than prototype oxime drugs? An answer derived from quantum chemical and steered molecular dynamics studies.

Mol Biosyst 2014; online early:

doi: 10.1039/c4mb00083h:

Lipid emulsion therapy Martin C, Gonzalez H, Ruiz S, Ribes D, Franchitto N, Minville V.

Acute respiratory distress syndrome following verapamil overdose treated with intravenous lipid emulsion: a rare life-threatening complication.

Ann Fr Anesth Réanim 2014; online early:

doi: 10.1016/j.annfar.2014.05.013:

Ozkan U, Osun A, Basarslan K, Senol S, Kaplan I, Alp H.

Effects of intralipid and caffeic acid phenethyl ester on neurotoxicity, oxidative stress, and acetylcholinesterase activity in acute chlorpyriphos intoxication.

Int J Clin Exp Med 2014; 7: 837-46.

Methylthioninium chloride (Methylene

blue) Patnaik S, Natarajan MM, James EJ, Ebenezer K.

Methylene blue unresponsive methemoglobinemia.


Oximes Horn G, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.

Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyryl-cholinesterase.

Arch Toxicol 2014; online early: doi: 10.1007/s00204-014-1288-5:

Ascorbic acid Rino PB, Scolnik D, Fustinana A, Mitelpunkt A, Glatstein M.

Ascorbic acid for the treatment of methemoglobinemia: the experience of a large tertiary care pediatric hospital.

Am J Ther 2014; online early:

doi: 10.1097/MJT.0000000000000028:

Caffeic acid phenethyl ester Ozkan U, Osun A, Basarslan K, Senol S, Kaplan I, Alp H.



Dexmedetomidine Walker A, Delle Donne A, Douglas E, Spicer K, Pluim T.

Novel use of dexmedetomidine for the treatment of anticholinergic toxidrome.


Disulfiram Amuchastegui T, Amuchastegui M, Donohue T.

Disulfiram – Alcohol reaction mimicking an acute coronary syndrome.

Conn Med 2014; 78: 81-4.

Extracorporeal treatments (general) Lavergne V, Ouellet G, Bouchard J, Galvao T, Kielstein JT, Roberts DM, Kanji S, Mowry JB, Calello DP, Hoffman RS, Gosselin S, Nolin TD, Goldfarb DS, Burdmann EA, Dargan PI, Decker BS, Hoegberg LC, Maclaren R, Megarbane B, Sowinski KM, Yates C, Mactier R, Wiegand T, Ghannoum M.

Guidelines for reporting case studies on extracorporeal treatments in poisonings: methodology.

Semin Dial 2014; online early: doi: 10.1111/sdi.12251:

Haemodiafiltration Abdelsalam MS, Althaf MM, Alfurayh O, Maghfoor I.

The utility of online haemodiafiltration in methotrexate poisoning.


Naloxone Anon.

In brief: a naloxone auto-injector (Evzio).

Med Lett Drugs Ther 2014; 56: 45.

18

Naloxone

Alcorn T.

America embraces treatment for opioid drug overdose.

Lancet 2014; 383: 1957-8.

Goodloe JM.

Not so fast on naloxone? There's growing support for non-paramedic use, but keep these cautions in mind.

EMS World 2014; 43: 51-2.

Sabzghabaee AM, Eizadi-Mood N, Yaraghi A, Zandifar S.

Naloxone therapy in opioid overdose patients: intranasal or intravenous? A randomized clinical trial.

Arch Med Sci 2014; 10: 309-14.

DRUGS General Allegaert K, van den Anker JN.

Adverse drug reactions in neonates and infants: a population tailored approach is needed.

Br J Clin Pharmacol 2014; online early:

doi: 10.1111/bcp.12430:

Bakhaidar M, Jan S, Farahat F, Attar A, Alsaywid B, Abuznadah W.

Pattern of drug overdose and chemical poisoning among patients attending an Emergency Department, Western Saudi Arabia.

J Community Health 2014; online early:

doi: 10.1007/s10900-014-9895-x:

Bezemer KDB, Smink BE, van Maanen R, Verschraagen M, de Gier JJ.



Binswanger IA, Blatchford PJ, Yamashita TE, Mueller S, Stern MF.

Trends in overdose deaths after release from state prison, 19992009.


Björnsson ES.


Semin Liver Dis 2014; 34: 115-22.

Bohnert AS, Walton MA, Ilgen MA, Cunningham RM, Barry K, Chermack S, Blow FC.

Overdose experiences among patients at an urban emergency department.


Chen M, Tung C-W, Shi Q, Guo L, Shi L, Fang H, Borlak J, Tong W.

A testing strategy to predict risk for drug-induced liver injury in humans using high-content screen assays and the 'rule-of-two' model.

Arch Toxicol 2014; 88: 1439-49.

Chen M, Borlak J, Tong W.

Predicting idiosyncratic drug-induced liver injury – Some recent advances.

Expert Rev Gastroenterol Hepatol 2014; online early: doi: 10.1586/17474124.2014.922871:

Deshmukh V, Kulkarni A, Bhargava S, Patil T, Ramdasi V, Gangal S, Godse V, Datar S, Gujar S, Sardeshmukh S.

Effectiveness of combinations of Ayurvedic drugs in alleviating drug toxicity and improving quality of life of cancer patients treated with chemotherapy.

Support Care Cancer 2014; online early:

doi: 10.1007/s00520-014-2294-0:

Fernández MD, Di Fazio V, Wille SM, Kummer N, Samyn N.

A quantitative, selective and fast ultra-high performance liquid chromatography tandem mass spectrometry method for the simultaneous analysis of 33 basic drugs in hair (amphetamines, cocaine, opiates, opioids and metabolites).

J Chromatogr B Biomed Sci Appl 2014; 965: 7-18.

Hampton T.

Mouse model may help screen drugs for liver toxicity.

JAMA 2014; 311: 2162.

Hayashi PH, Fontana RJ.

Clinical features, diagnosis, and natural history of drug-induced liver injury.

Semin Liver Dis 2014; 34: 134-44.

Heitmiller DR.

Serotonin syndrome: a concise review of a toxic state.

R I Med J (2013) 2014; 96: 33-5.

Koller AC, Salcido DD, Callaway CW, Menegazzi JJ.

Resuscitation characteristics and outcomes in suspected drug overdose-related out-of-hospital cardiac arrest.

Resuscitation 2014; online early:

doi: 10.1016/j.resuscitation.2014.05.036:

Korr M.

Community forum seeks ways to quell overdose epidemic in RI: less than 20 percent of physicians use prescription monitoring database.

R I Med J (2013) 2014; 97: 62-3.

Kotchev NP, George C.

Sub-acute presentation of neuroleptic malignant syndrome in a nursing home.


Maruyama Y, Yoshizawa K, Tsuruta F, Maruyama M, Fujimori K, Shigeno T, Fukushima M, Uehara T, Morita S, Joshita S, Umemura T, Tanaka E.

A case of repeated liver injury induced by different herbal medicines containing the same components.

Acta Hepatol Jpn 2014; 55: 214-20.

Ruhl DS, Cable BB, Martell DW.

Medication associated with hearing loss: 25 years of medical malpractice cases in the United States.

Otolaryngol Head Neck Surg 2014; online early: doi: 10.1177/0194599814536850:

Smirk CL, Bowman E, Doyle LW, Kamlin O.

Home-based detoxification for neonatal abstinence syndrome reduces length of hospital admission without prolonging treatment.

Acta Paediatr 2014; 103: 601-4.

Subedi B, Kannan K.

Mass loading and removal of select illicit drugs in two wastewater treatment plants in New York State and estimation of illicit drug usage in communities through wastewater analysis.

Environ Sci Technol 2014; 48: 6661-70.

19

DRUGS General Szeremeta M, Ptaszynska-Sarosiek I, Wardaszkab Z, Niemcunowicz-Janica A.

Analysis of the prevalence of medicines and psychoactive substances among drivers in the material of the department of forensic medicine at the medical university of bialystok.

Adv Clin Exp Med 2014; 23: 245-51.

Thakrar R, Shulman R, Bellingan G, Singer M.

Management of a mixed overdose of calcium channel blockers, -blockers and statins.


Vakkalanka P, Rushton WF, Hardison LS, Bishop MC, Haverstick DM, Holstege CP.

Evaluation of the initiation of urine drug screens intended for use in transfer patients.


doi: 10.1016/j.ajem.2014.06.011:

Williams DP.

Modeling hepatic drug metabolism and toxicity: where are we heading?

Future Med Chem 2014; 6: 725-7.

Acetaminophen (see paracetamol)

Amfetamines and MDMA (ecstasy) Alaee A, Zarghami M, Farnia S, Khademloo M, Khoddad T.

Comparison of brain white matter hyperintensities in methamphetamine and methadone dependent patients and healthy controls.

Iran J Radiol 2014; 11: e14275.

Kiyatkin EA, Kim AH, Wakabayashi KT, Baumann MH,

Shaham Y.

Critical role of peripheral vasoconstriction in fatal brain hyperthermia induced by MDMA (ecstasy) under conditions that mimic human drug use.

J Neurosci 2014; 34: 7754-62.

Litjens RP, Brunt TM, Alderliefste G-J, Westerink RH.

Hallucinogen persisting perception disorder and the serotonergic system: A comprehensive review including new MDMA-related clinical cases.

Eur Neuropsychopharmacol 2014; online early:

doi: 10.1016/j.euroneuro.2014.05.008:

Seibert J, Hysek CM, Penno CA, Schmid Y, Kratschmar DV, Liechti ME, Odermatt A.

Acute effects of 3,4-methylenedioxymethamphetamine and methylphenidate on circulating steroid levels in healthy subjects.

Neuroendocrinology 2014; online early:

doi: 10.1159/000364879:

Vakde T, Diaz M, Uday K, Duncalf R.

Rapidly reversible multiorgan failure after ingestion of "Molly" (pure 3,4-methylenedioxymethamphetamine): a case report.

J Med Case Reports 2014; 8: 204.

Anabolic steroids Luciano RL, Castano E, Moeckel G, Perazella MA.

Bile acid nephropathy in a bodybuilder abusing an anabolic androgenic steroid.

Am J Kidney Dis 2014; online early:

doi: 10.1053/j.ajkd.2014.05.010:

Anaesthetics Chiao S, Zuo Z.

A double-edged sword: volatile anesthetic effects on the neonatal brain.

Brain Sci 2014; 4: 273-94.

McEvoy MD, Hand WR, Stoll WD, Furse CM, Nietert PJ.

Adherence to guidelines for the management of local anesthetic systemic toxicity is improved by an electronic decision support tool and designated "reader".

Reg Anesth Pain Med 2014; 39: 299-305.

Weaver JM.

When can a normal dose be an overdose? who is at risk?

Anesth Prog 2014; 61: 45-6.

Bupivacaine Buck D, Kreeger R, Spaeth J.

Case discussion and root cause analysis: bupivacaine overdose in an infant leading to ventricular tachycardia.

Anesth Analg 2014; 119: 137-40.

Antiarrhythmics Borowicz KK, Banach M.

Antiarrhythmic drugs and epilepsy.

Pharmacol Rep 2014; 66: 545-51.

Amiodarone Fadahunsi O, Stull MS, Gupta S.

Acute amiodarone pulmonary toxicity following lung resection.

J Gen Intern Med 2014; 29: S295.

Dronedarone Smith H, Battjes E, Yan S, Kaakeh Y.

Chronic digoxin toxicity precipitated by dronedarone.


Antibiotics

Azithromycin Antoine SM, Banas E, Keogh S.

A rare case of toxic epidermal necrolysis (TEN) associated with the use of azithromycin.


Cefozopran Sawada Y, Kabashima-Kubo R, Hino R, Nakamura M.

Fatal case of toxic epidermal necrolysis caused by cefozopran and associated with psoriasis.

Acta Derm Venereol 2014; 94: 341-2.

Metronidazole Ng PS, S Hoffman R, Saini M.

Reversible metronidazole induced subacute cerebellar syndrome.

QJM 2014; online early: doi: 10.1093/qjmed/hcu115:

Anticholinergic drugs

Orphenadrine Rejdak K, Nieoczym D, Czuczwar M, Kis J, Wlaz P, Turski WA.

Orphenadrine-induced convulsive status epilepticus in rats responds to the NMDA antagonist dizocilpine.

Pharmacol Rep 2014; 66: 399-403.

20

Anticoagulants Champion S, Cleophax C, Voicu S, Sirol M, Deye N, Baud J.

Vitamin K1 antagonisation is not safe in high thromboembolic risk patients with over-anticoagulation.

Thérapie 2014; online early: doi: 10.2515/therapie/2014022:

Levine M, Goldstein JN.

Emergency reversal of anticoagulation: novel agents. Curr Neurol Neurosci Rep 2014; 14: 471.

Palareti G. Direct oral anticoagulants and bleeding risk (in comparison to vitamin K antagonists and heparins), and the treatment of bleeding.

Semin Hematol 2014; 51: 102-11.

Suryanarayan D, Schulman S.

Potential antidotes for reversal of old and new oral anti-coagulants.

Thromb Res 2014; 133 Suppl 2: S158-S166.

Dabigatran Levine M, Huang M, Carmelli G, Henderson SO, Thomas SH.

Failure of aminocaproic acid and tranexamic acid to reverse dabigatran induced coagulopathy.


Stollberger C, Krutisch G, Finsterer J.

Life-threatening epistaxis and red blood cell poly-agglutination under dabigatran.

Blood Coagul Fibrinolysis 2014; 25: 384-6.

Anticonvulsants

Lamotrigine Sathiya S, Ganesh M, Kalaivani P, Ranju V, Janani S, Pramila B, Saravana Babu C.

Prenatal exposure to lamotrigine: effects on postnatal development and behaviour in rat offspring.

ISRN Neurosci 2014; 2014: 163459.

Levetiracetam Anzellotti F, Franciotti R, Zhuzhuni H, D'Amico A, Thomas A, Onofrj M.

Nonepileptic seizures under levetiracetam therapy: a case report of forced normalization process. Neuropsychiatr Dis Treat 2014; 10: 959-64.

Paret N, Gouraud A, Bernard N, Bruel ML, Cottin J, Descotes J, Vial T.

Levetiracetam and breastfeeding: long-term follow-up. Fundam Clin Pharmacol 2014; 28: 23.

Phenytoin Sivathanu S, Sampath S, David HS, Rajavelu KK.

Myristicin and phenytoin toxicity in an infant.


Valproate Mojumder DK, De Oleo RR.

Differential ammonia decay kinetics indicates more than one concurrent etiological mechanism for symptomatic hyperammonemia caused by valproate overdose.

Indian J Pharmacol 2014; 46: 345-7.

Vázquez M, Fagiolino P, Maldonado C, Olmos I, Ibarra M, Alvariza S, Guevara N, Magallanes L, Olano I. Hyperammonemia associated with valproic acid concen-trations. BioMed Res Int 2014; 2014: 217269.

Antidepressants Huybrechts KF, Palmsten K, Avorn J, Cohen LS, Holmes LB, Franklin JM, Mogun H, Levin R, Kowal M, Setoguchi S, Hernández-Díaz S.

Antidepressant use in pregnancy and the risk of cardiac defects.

N Engl J Med 2014; 370: 2397-407.

Antifungal drugs

Chlorphenesin Johnson W, Jr., Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Jr., Shank RC, Slaga TJ, Snyder PW, Andersen FA.

Safety assessment of chlorphenesin as used in cosmetics.

Int J Toxicol 2014; 33: 5S-15S.

Antihistamines

Diphenhydramine Walker A, Delle Donne A, Douglas E, Spicer K, Pluim T.

Novel use of dexmedetomidine for the treatment of anticholinergic toxidrome.


Antineoplastics Nelson WK, Moore J, Grasso JA, Barbarotta L, Fischer DS.

Development of a policy and procedure for accidental chemotherapy overdose.

Clin J Oncol Nurs 2014; online early:

doi: 10.1188/14.CJON.18-04AP:

Cisplatin Morgan KP, Snavely AC, Wind LS, Buie LW, Grilley-Olson J, Walko CM, Weiss J.

Rates of renal toxicity in cancer patients receiving cisplatin with and without mannitol.


Antipsychotics Okoli C, Degrand D, Du Beau C.

Chicken or Egg? Unscrambling agitation and antipsychotics.

J Am Geriatr Soc 2014; 62: S24-S25.

Omar HR, Sprenker C, Karlnoski R, Mangar D, Camporesi EM.

The use of isoproterenol and phenytoin to reverse torsade de pointes.

Am J Emerg Med 2014; 32: 683.

Antituberculous drugs

Ethambutol Geyer HL, Herskovitz S, Slamovits TL, Schaumburg HH.



doi: 10.1097/WNO.0000000000000141:

Antiviral drugs

Efavirenz Abdissa A, Wiesner L, McIlleron H, Friis H, Andersen AB, Kæstel P.

Evaluation of an immunoassay for determination of plasma efavirenz concentrations in resource-limited settings.

J Int AIDS Soc 2014; 17: 18979.

21

Baclofen Bonnet B, Horowicz S, Ginisty S, Batel P, Carlier P, Eftekhari P.

Adverse reactions in patients treated with baclofen for alcohol dependence: a descriptive study of cases reported to pharmacovigilance center of Paris Fernand Widal.


Jantea R.

A paradoxical manifestation of baclofen toxicity.


Zaki SA, Khanage YG.

Baclofen induced coma in an infant.

J Pediatr Neurosci 2014; 9: 86-8.

Zieman G, Burns R.

Intrathecal baclofen toxicity mimicking nonconvulsive status epilepticus.

Neurology 2014; 82: P6.026.

Barbiturates Pugin D, Foreman B, De Marchis GM, Fernandez A, Schmidt JM, Czeisler BM, Mayer SA, Agarwal S, Lesch C, Lantigua H, Claassen J.

Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study.

Crit Care 2014; 18: R103.

Pentobarbital Pugin D, Foreman B, De Marchis GM, Fernandez A, Schmidt JM, Czeisler BM, Mayer SA, Agarwal S, Lesch C, Lantigua H, Claassen J.

Is pentobarbital safe and efficacious in the treatment of super-refractory status epilepticus: a cohort study.

Crit Care 2014; 18: R103.

Benzodiazepines Mendoza A, Rodríguez-Gil JL, González-Alonso S, Mastroianni N, López de Alda M, Barceló D, Valcárcel Y.


Environ Int 2014; 70C: 76-87.

Beta blockers Palatnick W, Jelic T.



Propranolol Bourgine J, Cesbron A, Coquerel A, Debruyne D, Loilier M, Lelong-Boulouard V.

Acute poisoning with sustained release propranolol and acetaminophen: delayed effects.


Beta-hydroxybutyrate Palmiere C, Werner D.

Post-mortem beta-hydroxybutyrate determination in synovial fluid.

Forensic Sci Int 2014; online early:

doi: 10.1016/j.forsciint.2014.04.034:

Caffeine Chrysant SG, Chrysant GS.

Cardiovascular complications from consumption of high energy drinks: recent evidence.

J Hum Hypertens 2014; online early:

doi: 10.1038/jhh.2014.47:

Silva AC, de Oliveira Ribeiro NP, de Mello Schier AR, Pereira VM, Vilarim MM, Pessoa TM, Arias-Carrion O, Machado S, Nardi AE.

Caffeine and suicide: a systematic review.

CNS Neurol Disord Drug Targets 2014; online early: doi: 10.2174/1871527313666140612123656:

Calcium carbonate Rösche J, Sieveking C, Kampf C, Benecke R.

Creutzfeldt-Jakob-like syndrome due to hypercalcemic encephalopathy.

Clin EEG Neurosci 2014; online early:

doi: 10.1177/1550059414529764:

Calcium channel blockers Palatnick W, Jelic T.



Diltiazem Rhoads DD, Sivak RA, Palmer OM.

Plasma abnormalities following overdose.

Clin Chem 2014; 60: 1020-1.

Verapamil Izdes S, Altintas ND, Soykut C.

Acute respiratory distress syndrome after verapamil intoxication: case report and literature review.

Acta Clin Belg 2014; 69: 116-9.

Martin C, Gonzalez H, Ruiz S, Ribes D, Franchitto N, Minville V.

Acute respiratory distress syndrome following verapamil overdose treated with intravenous lipid emulsion: a rare life-threatening complication.

Ann Fr Anesth Réanim 2014; online early:

doi: 10.1016/j.annfar.2014.05.013:

Cannabis (marijuana) Allsop DJ, Alperstein D, Copeland J.

Neural markers for recovery in cannabis withdrawal.


Behonick G, Shanks KG, Firchau DJ, Mathur G, Lynch CF, Nashelsky M, Jaskierny DJ, Meroueh C.

Four postmortem case reports with quantitative detection of the synthetic cannabinoid, 5F-PB-22.


doi: 10.1093/jat/bku048:

Filip MG, Adamczyk PA, Bystrowska B, Smaga I, Przegali Ski E.

Cannabinoid modification of cocaine action.

Pharmacol Rep 2014; 66: 331.

Hughes JR, Fingar JR, Budney AJ, Naud S, Helzer JE, Callas PW.

Marijuana use and intoxication among daily users: an intensive longitudinal study.

Addict Behav 2014; 39: 1464-70.

22

Cannabis (marijuana)

Hunault CC, Böcker KB, Stellato RK, Kenemans JL, De Vries I, Meulenbelt J.

Acute subjective effects after smoking joints containing up to 69 mg delta9-tetrahydrocannabinol in recreational users: a randomized, crossover clinical trial.

Psychopharmacology 2014; online early:

doi: 10.1007/s00213-014-3630-2:

Pape E, Roman E, Frikha Z, Scala-Bertola J, Tournebize J, Bornert-Keller N, Gibaja V, Petitpain N, Moulin F, Gambier N, Kahn JP.

Acute myocardial infarction in a cannabis smoker: role of cannabis?


Temple EC.

Commentary on van der Pol et al. (2014): reconsidering the association between cannabis exposure and dependence.

Addiction 2014; 109: 1110-1.

Volkow ND, Baler RD, Compton WM, Weiss SRB.

Adverse health effects of marijuana use.

N Engl J Med 2014; 370: 2219-27.

Cocaine Anon.

From the archive: "Delayed" cocaine poisoning.

Br Dent J 2014; 216: 614.

Filip MG, Adamczyk PA, Bystrowska B, Smaga I, Przegali Ski E.

Cannabinoid modification of cocaine action.

Pharmacol Rep 2014; 66: 331.

Poon S, Gareri J, Walasek P, Koren G.

Norcocaine in human hair as a biomarker of heavy cocaine use in a high risk population.


Prisciandaro JJ, Joseph JE, Myrick H, McRae-Clark AL, Henderson S, Pfeifer J, Brady KT.

The relationship between years of cocaine use and brain activation to cocaine and response inhibition cues.

Addiction 2014; online early: doi: 10.1111/add.12666:

Tang Y, Martin NL, Cotes RO.

Cocaine-induced psychotic disorders: presentation, mech-anism, and management.

J Dual Diagn 2014; 10: 98-105.

Trimarchi M, Bertazzoni G, Bussi M.

Cocaine induced midline destructive lesions.

Rhinology 2014; 52: 104-11.

Cytotoxic drugs Weidmann A, Foulkes AC, Kirkham N, Reynolds NJ.

Methotrexate toxicity during treatment of chronic plaque psoriasis: a case report and review of the literature.

Dermatol Ther (Heidelb) 2014; online early:

doi: 10.1007/s13555-014-0056-z:

Anthracyclines Raj S, Franco VI, Lipshultz SE.

Anthracycline-induced cardiotoxicity: a review of patho-physiology, diagnosis, and treatment.

Curr Treat Options Cardiovasc Med 2014; 16: 315.

Fluorouracil Liao F, Wang L, Qin SK, Li XW, Yang NR, Yao L, Zhang Y, Xun C, Yan F. Cardiac toxicity caused by fluorouracil: a report of 9 cases and review of literature. J Pract Oncol 2014; 29: 183-5.

Methotrexate Abdelsalam MS, Althaf MM, Alfurayh O, Maghfoor I. The utility of online haemodiafiltration in methotrexate poisoning. BMJ Case Rep 2014; doi: 10.1136/bcr-2014-203530: May J, Carson KR, Butler S, Liu W, Bartlett NL, Wagner-Johnston ND. High incidence of methotrexate associated renal toxicity in patients with lymphoma: a retrospective analysis. Leuk Lymphoma 2014; 55: 1345-9. Strober BE. Methotrexate-induced liver toxicity: replacing the liver biopsy. JAMA Dermatol 2014; online early: doi: 10.1001/jamadermatol.2014.681: Uce Ozkol H, Toptas T, Calka O, Akdeniz N. The efficiency of granulocyte colony-stimulating factor in hemorrhagic mucositis and febrile neutropenia resulted from methotrexate toxicity. Cutan Ocul Toxicol 2014; online early: doi: 10.3109/15569527.2014.918139:

Digoxin Ban H, Rachko M, Saeed M. Uncommon presentation of digoxin toxicity in setting of acute on chronic kidney disease and aggressive diuretic use requiring urgent treatment. J Gen Intern Med 2014; 29: S461. Palatnick W, Jelic T. Emergency department management of calcium-channel blocker, beta blocker, and digoxin toxicity. Emerg Med Pract 2014; 16: 1-19. Smith H, Battjes E, Yan S, Kaakeh Y. Chronic digoxin toxicity precipitated by dronedarone. Ann Pharmacother 2014; 48: 923-7.

Endostatin Guo L, Geng X, Chen Y, Qi F, Liu L, Miao Y, Lin Z, Yu M, Li Z, Fu Y, Li B, Luo Y. Pre-clinical toxicokinetics and safety study of MES, a PEGylated recombinant human endostatin, in rhesus monkeys. Regul Toxicol Pharmacol 2014; online early: doi: 10.1016/j.yrtph.2014.05.019:

Ephedrone Poniatowska R, Lusawa M, Skierczynska A, Makowicz G, Habrat B, Sienkiewicz-Jarosz H. MRI brain findings in ephedrone encephalopathy associated with manganese abuse: single-center perspective. Pol J Radiol 2014; 79: 150-5.

Gamma hydroxybutyrate Kang S, Oh SM, Chung KH, Lee S. A surrogate analyte-based LC-MS/MS method for the determination of -hydroxybutyrate (GHB) in human urine

and variation of endogenous urinary concentrations of GHB. J Pharm Biomed Anal 2014; 98: 193-200.

23

Herbal medicines, ethnic remedies and dietary supplements Cox AR.

Regulation of herbal drugs: a pragmatic public health approach?

Br Med J 2014; 348: g4156.

Gilbert JD, Musgrave IF, Hoban C, Byard RW.

Lethal hepatocellular necrosis associated with herbal polypharmacy in a patient with chronic hepatitis B infection.


Langrand J, Regnault H, Cachet X, Bouzidi C, Villa AF, Serfaty L, Garnier R, Michel S.

Toxic hepatitis induced by a herbal medicine: Tinospora crispa.

Phytomedicine 2014; 21: 1120-3.

Navarro VJ, Lucena MI.

Hepatotoxicity induced by herbal and dietary supplements.

Semin Liver Dis 2014; 34: 172-93.

Parker L, Hernandez R, Han B.

Moringa: an herbal medicine with potential drug interactions.


Tangchaivang N.

Acute hepatotoxicity: a complication of chaparral ingestion.


Wise J.

Increase in reports of toxicity from fat burning supplement seen in UK.

Br Med J 2014; 348: g4188.

Heroin (diacetylmorphine) Baird C.

Prescription drugs or heroin: the overdoses continue.

J Addict Nurs 2014; 25: 63-5.

Gadiraju TV, Singh DK, Gokaraju S, Farmer MJ.

Toxic leukoencephalopathy from heroin overdose – Atypical presentation and recovery with residual autonomic dysfunction and spasticity.


Moore S, Firestein C, Hust K.

Heroin lies the problem.


Rambod M, Elhanafi S, Mukherjee D.

Brugada phenocopy in concomitant ethanol and heroin overdose.

Ann Noninvasive Electrocardiol 2014; online early:

doi: 10.1111/anec.12171:

Unick G, Rosenblum D, Mars S, Ciccarone D.

The relationship between US heroin market dynamics and heroin-related overdose, 1992–2008.

Addiction 2014; online early: doi: 10.1111/add.12664:

Hypoglycaemics

Metformin Acquistapace G, Rossi M, Garbi M, Cosci P, Canetta C, Manelli A, Ricevuti G.

Acute metformin intoxication: 2012 experience of Emergency Departement of Lodi, Italy.

Clin Chem Lab Med 2014; online early:

doi: 10.1515/cclm-2014-0208:

Donnino M, Montissol S, Andersen LW, Chase M, Liu X.

Metformin inhibits pyruvate dehydrogenase at high dosages: a potential mechanism for lactic acidosis.


Ncomanzi D, Sicat RMR, Sundararajan K.

Metformin-associated lactic acidosis presenting as an ischemic gut in a patient who then survived a cardiac arrest: a case report.

J Med Case Reports 2014; 8: 159.

Immunosuppressants

Mycophenolate Alex R, Mathew M, Arul S, Kundavaram A.

Overdose of mycophenolate mofetil managed in a secondary care hospital in South India.

Indian J Pharmacol 2014; 46: 337-8.

Hassan M, Hadid H, Paje D.

An interesting case of cellcept toxicity.


Insulin Wunder C, Kauert GF, Toennes SW.

Factors leading to the degradation/loss of insulin in postmortem blood samples.


Isoproterenol Riha M, Voprsalová M, Pilarová V, Semecky V, Holecková M, Vávrová J, Palicka V, Filipsky T, Hrdina R, Nováková L, Mladenka P.

Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity.

Naunyn Schmiedebergs Arch Pharmacol 2014; online early: doi: 10.1007/s00210-014-0995-z:

Isotretinoin Lambe J.

Adding isotretinoin to lithium carbonate probably caused mild lithium toxicity.

Aust N Z J Psychiatry 2014; online early:

doi: 10.1177/0004867414536935:

Khat Katz DP, Bhattacharya D, Bhattacharya S, DeRuiter J, Clark CR, Suppiramaniam V, Dhanasekaran M.

Synthetic cathinones: "a khat and mouse game".


doi: 10.1016/j.toxlet.2014.06.020:

Krokodil Mullins ME, Schwarz ES.

'Krokodil' in the United States is an urban legend and not a medical fact.

Am J Med 2014; 127: e25.

Lithium Davis SS, Jr.

Clinical challenges of bariatric surgery for patients with psychiatric disorders. commentary on: "lithium toxicity following Roux-en-Y gastric bypass".

Bariatr Surg Pract Patient Care 2014; 9: 84-5.


Takotsubo cardiomyopathy associated with lithium intoxication in bipolar disorder: a case report.


24

Lithium

Lambe J.



doi: 10.1177/0004867414536935:

Madrigal F, Barrientos-Calvo I.

Hypernatremia in a patient with bipolar disorder treated with lithium and dural sinus thrombosis.


Morse RJ, DuBeau C.

The lithium linings playbook: competing sequelae of long-term use.


Mephedrone den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E.

Keto amphetamine toxicity – Focus on the redox reactivity of the cathinone designer drug mephedrone.



Methadone Alaee A, Zarghami M, Farnia S, Khademloo M, Khoddad T.

Comparison of brain white matter hyperintensities in methamphetamine and methadone dependent patients and healthy controls.

Iran J Radiol 2014; 11: e14275.

Iwersen-Bergmann S, Jungen H, Andresen-Streichert H, Müller A, Elakkary S, Püschel K, Heinemann A.

Intravenous methadone application as a serious risk factor for an overdose death: methadone-related fatalities in Hamburg from 2007 to 2012.

Int J Legal Med 2014; online early: doi: 10.1007/s00414-014-1017-x:

Methcathinone Golasik M, Wodowski G, Gomólka E, Herman M, Piekoszewski W.

Urine as a material for evaluation of exposure to manganese in methcathinone users.


doi: 10.1016/j.jtemb.2014.04.005:

Methoxetamine Imbert L, Boucher A, Delhome G, Cueto T, Boudinaud M, Maublanc J, Dulaurent S, Descotes J, Lachâtre G, Gaulier J-M.



doi: 10.1093/jat/bku052:

Mitoxantrone Davide Severino DJ, Costa CC, Marta LM, Valente FX, Martins VB, Durao DL, Pitta ML, Monteiro IM, Leal ML.

Acute heart failure secondary to mitoxantrone toxicity.

Eur J Heart Fail 2014; 16: 243.

Nicotine Anon.

Nicotine replacement products: poisoning in children.

Prescrire Int 2014; 23: 126-8.

Harrell PT, Simmons VN, Correa JB, Padhya TA, Brandon TH. Electronic nicotine delivery systems ("e-cigarettes"): review of safety and smoking cessation efficacy. Otolaryngol Head Neck Surg 2014; online early: doi: 10.1177/0194599814536847: Miller A. Nicotine poisoning increase due to e-cigs. Can Med Assoc J 2014; online early: doi: 10.1503/cmaj.109-4818: Suh-Lailam BB, Haglock-Adler CJ, Carlisle HJ, Ohman T, McMillin GA. Reference interval determination for anabasine: a biomarker of active tobacco use. J Anal Toxicol 2014; online early: doi: 10.1093/jat/bku059: Yoo S-J, Park S-J, Kim B-S, Lee K, Lim H-S, Kim J-S, Kim I-S. Airborne nicotine concentrations in the workplaces of tobacco farmers. J Prev Med Public Health 2014; 47: 144-9.

NSAIDs Tanaka S, Asahina Y, Satoh H, Miki A, Hori S, Sawada Y. Questionnaire survey about NSAIDs use in late pregnancy for pharmacists and physicians. Yakugaku Zasshi 2014; 134: 757-66.

Diclofenac Odom DM, Mladsi DM, Saag KG, Sherif BN, Miles L, Ronquest N, Wang J. Relationship between diclofenac dose and risk of gastro-intestinal and cardiovascular events: meta-regression based on two systematic literature reviews. Clin Ther 2014; 36: 906-17.

Opioids Anon. DOH issues emergency regulations on expanding use of Narcan to prevent opioid overdose deaths. R I Med J (2013) 2014; 97: 49. Anon. Enhanced surveillance for opioid overdose in Rhode Island. R I Med J (2013) 2014; 96: 66. Alcorn T. America embraces treatment for opioid drug overdose. Lancet 2014; 383: 1957-8. Fernández MdMR, Van Durme F, Wille SMR, Di Fazio V, Kummer N, Samyn N. Validation of an automated solid-phase extraction method for the analysis of 23 opioids, cocaine, and metabolites in urine with ultra-performance liquid chromatography-tandem mass spectrometry. J Anal Toxicol 2014; 38: 280-8. Le Lait M-C, Martinez EM, Severtson SG, Lavery SA, Bucher-Bartelson B, Dart RC. Assessment of prescription opioid intentional exposures across the rural-urban continuum in the United States using both population and drug availability rates. Pharmacoepidemiol Drug Saf 2014; online early: doi: 10.1002/pds.3653: Lövborg H, Holmlund M, Hägg S. Medication errors related to transdermal opioid patches: lessons from a regional incident reporting system. BMC Pharmacol Toxicol 2014; 15: 31.

25

Opioids

Sabzghabaee AM, Eizadi-Mood N, Yaraghi A, Zandifar S.

Naloxone therapy in opioid overdose patients: intranasal or intravenous? A randomized clinical trial.

Arch Med Sci 2014; 10: 309-14.

Yuan Q, Rubic M, Seah J, Rae C, Wright IM, Kaltenbach K, Feller JM, Abdel-Latif ME, Chu C, Oei JL, BOB COLLABORATIVE GROUP.

Do maternal opioids reduce neonatal regional brain volumes? A pilot study.

J Perinatol 2014; online early: doi: 10.1038/jp.2014.111:

Buprenorphine Belsey SL, Couchman L, Flanagan RJ.

Buprenorphine detection in urine using liquid chroma-tography-high-resolution mass spectrometry: comparison with cloned enzyme donor immunoassay (ThermoFisher) and homogeneous enzyme immunoassay (Immunalysis).


doi: 10.1093/jat/bku060:

Fentanyl Mercado-Crespo MC, Sumner SA, Spelke MB, Sugerman DE, Stanley C, EIS Officer CDC.

Notes from the field: increase in fentanyl-related overdose deaths – Rhode Island, November 2013-March 2014.

MMWR Morb Mortal Wkly Rep 2014; 63: 531.

Morphine Landais A.

Severe memory impairment following acute morphine intoxication.

J Neurol Sci 2014; online early:

doi: 10.1016/j.jns.2014.05.061:

Paracetamol (acetaminophen) Bourgine J, Cesbron A, Coquerel A, Debruyne D, Loilier M, Lelong-Boulouard V.

Acute poisoning with sustained release propranolol and acetaminophen: delayed effects.


Graudins A.

Overdose with modified-release paracetamol (Panadol Osteo®) presenting to a metropolitan emergency medicine network: a case series.

Emerg Med Australas 2014; online early:

doi: 10.1111/1742-6723.12249:

Heard K, Bui A, Mlynarchek SL, Green JL, Bond GR, Clark RF, Kozer E, Koff RS, Dart RC.

Toxicity from repeated doses of acetaminophen in children: assessment of cause.

Am J Ther 2014; 21: 174-83.

Koppen A, Van Riel A, de Vries I, Meulenbelt J.

Recommendations for the paracetamol treatment nomogram and side effects of N-acetylcysteine.

Neth J Med 2014; 72: 251-7.

Willey JZ, Tolchin BD.

Liver transplant for intentional acetaminophen overdose and hepatic encephalopathy: a conflict between beneficence and justice.


Xie Y, Mcgill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H.

Mechanisms of acetaminophen-induced cell death in primary human hepatocytes.

Toxicol Appl Pharmacol 2014; online early:

doi: 10.1016/j.taap.2014.05.010:

Psilocybin Bradstreet MP, Johnson MW, MacLean KA, Griffiths RR.

Characterization of challenging experiences (i.e., bad trips) after ingesting psilocybin.

Drug Alcohol Depend 2014; 140: e18-e19.

Psychotropic drugs Cantilino A, Lorenzo L, de Paula JA, Einarson A.

Use of psychotropic medications during pregnancy: perception of teratogenic risk among physicians in two Latin American countries.

Rev Bras Psiquiatr 2014; 36: 106-10.

Sodium nitrate Joosen D, Stolk L, Henry R.

A non-fatal intoxication with a high-dose sodium nitrate.


SSRIs and SNRIs

Escitalopram Kemp AH, Outhred T, Saunders S, Brunoni AR, Nathan PJ, Malhi GS.

Impact of escitalopram on vagally mediated cardiovascular function in healthy participants: implications for under-standing differential age-related, treatment emergent effects.

Psychopharmacology 2014; 231: 2281-90.

Sertraline Kaprinis S, Parlapani E, Raikos N, Goulas A, Karpouza V.

Psychotic episode associated with sertraline and drug-related delirium: a case report.


Statins Zarek J, Koren G.

The fetal safety of statins: a systematic review and meta-analysis.

J Obstet Gynaecol Can 2014; 36: 506-9.

Stimulant drugs Nader MA, Balster RL, Henningfield JE.

William L. Woolverton: a case history in unraveling the behavioral pharmacology of stimulants.

Neuropharmacology 2014; online early:

doi: 10.1016/j.neuropharm.2014.05.004:

Substance abuse Akin J, Tarantino N, Johnson JA, Kuperminc G.

Polydrug use among emergency department patients receiving SBIRT services.

Drug Alcohol Depend 2014; 140: e3-e4.

Aoun EG, Christopher PP, Ingraham JW.

Emerging drugs of abuse: clinical and legal considerations.

R I Med J (2013) 2014; 96: 41-5.

26

Substance abuse

Araujo AM, Valente MJ, Carvalho M, Dias da Silva D, Gaspar H, Carvalho F, de Lourdes Bastos M, Guedes de Pinho P.

Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of 'legal high' packages containing synthetic cathinones.

Arch Toxicol 2014; online early:

doi: 10.1007/s00204-014-1278-7:

Baird C.

Prescription drugs or heroin: the overdoses continue.

J Addict Nurs 2014; 25: 63-5.

Brust JC.

Neurologic complications of illicit drug abuse.


Espy RD, Teunissen B, Manicke NE, Ren Y, Ouyang Z, van Asten A, Cooks RG.

Paper spray and extraction spray mass spectrometry for the direct and simultaneous quantification of eight drugs of abuse in whole blood.

Anal Chem 2014; online early: doi: 10.1021/ac5016408:

Gjersing L, Bretteville-Jensen AL.

Gender differences in mortality and risk factors in a 13-year cohort study of street-recruited injecting drug users.

BMC Public Health 2014; 14: 440.

Mendoza A, Rodríguez-Gil JL, González-Alonso S, Mastroianni N, López de Alda M, Barceló D, Valcárcel Y.


Environ Int 2014; 70C: 76-87.

Mullins ME, Schwarz ES.

'Krokodil' in the United States is an urban legend and not a medical fact.

Am J Med 2014; 127: e25.

Paillet-Loilier M, Cesbron A, Le Boisselier R, Bourgine J, Debruyne D.

Emerging drugs of abuse: current perspectives on substituted cathinones.

Subst Abuse Rehabil 2014; 5: 37-52.

Shin YM.

A night of excess leads to a near death experience.


Wagner KD, Armenta RF, Roth AM, Maxwell JC, Cuevas-Mota J, Garfein RS.

Use of synthetic cathinones and cannabimimetics among injection drug users in San Diego, California.

Drug Alcohol Depend 2014; 141: 99-106.

Watson R.

Heroin and cannabis use is declining but new drugs show increase, says EU report.

Br Med J 2014; 348: g3647.

Tamoxifen Henry NL.

Endocrine therapy toxicity: management options.

Am Soc Clin Oncol Educ Book 2014; 34: e25-e30.

Thalidomide Hui JY, Hoffmann M, Kumar G.

Embryo-fetal exposure and developmental outcome of thalidomide following oral and intravaginal administration to pregnant rabbits.


doi: 10.1016/j.reprotox.2014.05.002:

Valsartan Rhoads DD, Sivak RA, Palmer OM.

Plasma abnormalities following overdose.

Clin Chem 2014; 60: 1020-1.

Veterinary products

Arprinocid Wu H, Xiao W, Zhang K, Xue F, Zhang C, Yan M, Wang X, Jiang S.

Acute and subchronic toxicity of arprinocid in Sprague-Dawley rats.


doi: 10.1016/j.yrtph.2014.05.017:

Vitamins

Calciferol Baughman RP, Lower EE.

Goldilocks, vitamin D and sarcoidosis.

Arthritis Res Ther 2014; 16: 111.

Genzen JR.

Hypercalcemic crisis due to vitamin D toxicity.

Lab Med 2014; 45: 147-50.

Cholecalciferol Rösche J, Sieveking C, Kampf C, Benecke R.

Creutzfeldt-Jakob-like syndrome due to hypercalcemic encephalopathy.

Clin EEG Neurosci 2014; online early:

doi: 10.1177/1550059414529764:

CHEMICAL INCIDENTS AND

POLLUTION Air pollution Brugha R, Grigg J.

Urban air pollution and respiratory infections.

Paediatr Respir Rev 2014; 15: 194-9.

Enkhmaa D, Warburton N, Javzandulam B, Uyanga J, Khishigsuren Y, Lodoysamba S, Enkhtur S, Warburton D.

Seasonal ambient air pollution correlates strongly with spontaneous abortion in Mongolia.

BMC Pregnancy Childbirth 2014; 14: 146.

Friedrich MJ.

Spontaneous abortions in mongolia linked to high air pollutant levels.

JAMA 2014; 311: 2372.

Hamra GB, Guha N, Cohen A, Laden F, Raaschou-Nielsen O, Samet JM, Vineis P, Forastiere F, Saldiva P, Yorifuji T, Loomis D.

Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis.


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27

Air pollution

Kumar A, Singh BP, Punia M, Singh D, Kumar K, Jain VK. Assessment of indoor air concentrations of VOCs and their associated health risks in the library of Jawaharlal Nehru University, New Delhi. Environ Sci Pollut Res 2014; 21: 2240-8. Nieuwenhuijsen MJ, Basagaña X, Dadvand P, Martinez D, Cirach M, Beelen R, Jacquemin B. Air pollution and human fertility rates. Environ Int 2014; 70: 9-14. Patelarou E, Kelly FJ. Indoor exposure and adverse birth outcomes related to fetal growth, miscarriage and prematurity – A systematic review. Int J Environ Res Public Health 2014; 11: 5904-33. Pereira G, Bell ML, Lee HJ, Koutrakis P, Belanger K. Sources of fine particulate matter and risk of preterm birth in Connecticut, 2000–2006: a longitudinal study. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307741: Puett RC, Hart JE, Yanosky JD, Spiegelman D, Wang M, Fisher JA, Hong B, Laden F. Particulate matter air pollution exposure, distance to road, and incident lung cancer in the nurses' health study cohort. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307490: Rappazzo KM, Daniels JL, Messer LC, Poole C, Lobdell DT. Exposure to fine particulate matter during pregnancy and risk of preterm birth among women in New Jersey, Ohio, and Pennsylvania, 2000-2005. Environ Health Perspect 2014; online early: doi: 10.1289/ehp.1307456: Urman R, McConnell R, Islam T, Avol EL, Lurmann FW, Vora H, Linn WS, Rappaport EB, Gilliland FD, Gauderman WJ. Associations of children's lung function with ambient air pollution: Joint effects of regional and near-roadway pollutants. Thorax 2014; 69: 540-7. Zhang Z, Wang J, Chen L, Chen X, Sun G, Zhong N, Kan H, Lu W. Impact of haze and air pollution-related hazards on hospital admissions in Guangzhou, China. Environ Sci Pollut Res 2014; 21: 4236-44.

Exhaust fumes Newman NC, Ryan PH, Huang B, Beck AF, Sauers HS, Kahn RS. Traffic-related air pollution and asthma hospital readmission in children: a longitudinal cohort study. J Pediatr 2014; 164: 1396-402. Yamazaki S, Shima M, Nakadate T, Ohara T, Omori T, Ono M, Sato T, Nitta H. Association between traffic-related air pollution and devel-opment of asthma in school children: cohort study in Japan. J Expos Sci Environ Epidemiol 2014; 24: 372-9.

Chemical incidents Close RM, Maguire H, Etherington G, Brewin CR, Fong K, Saliba V, Barker RM, Leonardi GS. Preparedness for a major incident: creation of an epidemiology protocol for a health protection register in England. Environ Int 2014; online early: doi: 10.1016/j.envint.2014.05.003:

Cocker J, Jones K, Bos PM.

Biological monitoring guidance values for chemical incidents.


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D'Andrea MA, Reddy GK.

Health risks associated with crude oil spill exposure.

Am J Med 2014; online early:

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Harold PD, de Souza AS, Louchart P, Russell D, Brunt H.

Development of a risk-based prioritisation methodology to inform public health emergency planning and preparedness in case of accidental spill at sea of hazardous and noxious substances (HNS).

Environ Int 2014; online early:

doi: 10.1016/j.envint.2014.05.012:

Konkel L.

Data for disaster planning: risk factors for internal radiation exposures after Fukushima.

Environ Health Perspect 2014; 122: A166.

Leary AD, Schwartz MD, Kirk MA, Ignacio JS, Wencil EB, Cibulsky SM.

Evidence-based patient decontamination: an integral component of mass exposure chemical incident planning and response.

Disaster Med Public Health Prep 2014; online early:

doi: 10.1017/dmp.2014.41:

Leng G, Gries W.

Biomonitoring following a chemical incidence with acrylonitrile and ethylene in 2008.


doi: 10.1016/j.toxlet.2014.06.027:

Smolders R, Colles A, Cornelis C, Van HM, Chovanova H, Wildemeersch D, Mampaey M, Van Campenhout K.

Key aspects of a Flemish system to safeguard public health interests in case of chemical release incidents.


doi: 10.1016/j.toxlet.2014.05.013:

Wyke S, Peña-Fernández A, Brooke N, Duarte-Davidson R.

The importance of evaluating the physicochemical and toxicological properties of a contaminant for remediating environments affected by chemical incidents.

Environ Int 2014; online early:

doi: 10.1016/j.envint.2014.05.002:

Pollution and hazardous waste Croes K, Den Hond E, Bruckers L, Loots I, Morrens B, Nelen V, Colles A, Schoeters G, Sioen I, Covaci A, Vandermarken T, Van Larebeke N, Baeyens W.

Monitoring chlorinated persistent organic pollutants in adolescents in Flanders (Belgium): concentrations, trends and dose-effect relationships (FLEHS II).

Environ Int 2014; 71C: 20-8.

Jeng HA.



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28

Pollution and hazardous waste

Kumar J, Lind PM, Salihovic S, Van Bavel B, Ingelsson E, Lind L.

Persistent organic pollutants and inflammatory markers in a cross-sectional study of elderly Swedish people: the PIVUS cohort.


doi: 10.1289/ehp.1307613:

Sharma BM, Bharat GK, Tayal S, Nizzetto L, Larssen T.

The legal framework to manage chemical pollution in India and the lesson from the persistent organic pollutants (POPs).


Xu X, Zhang Y, Yekeen TA, Li Y, Zhuang B, Huo X.

Increase male genital diseases morbidity linked to informal electronic waste recycling in Guiyu, China.

Environ Sci Pollut Res 2014; 21: 3540-5.

Water pollution Saint-Jacques N, Parker L, Brown P, Dummer TJB.

Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence.

Environ Health 2014; 13: 44.

CHEMICALS General Anderson AR, Welles WL, Drew J, Orr MF.

The distribution and public health consequences of releases of chemicals intended for pool use in 17 states, 2001–2009.

J Environ Health 2014; 76: 10-5.

Blanes-Vidal V, Bælum J, Nadimi ES, Løfstrøm P, Christensen LP.

Chronic exposure to odorous chemicals in residential areas and effects on human psychosocial health: dose-response relationships.


Egilman D.

Workers and consumers should not be exposed to chemicals that have not been tested for toxicity.


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Norlen H, Worth AP, Gabbert S.

A tutorial for analysing the cost-effectiveness of alternative methods for assessing chemical toxicity: the case of acute oral toxicity prediction.

Altern Lab Anim 2014; 42: 115-27.

Acrylonitrile Leng G, Gries W.



doi: 10.1016/j.toxlet.2014.06.027:

Alcohol (ethanol) Amuchastegui T, Amuchastegui M, Donohue T.

Disulfiram – Alcohol reaction mimicking an acute coronary syndrome.

Conn Med 2014; 78: 81-4.

Dinh MM, Bein KJ, Roncal S, Martiniuk ALC, Boufous S.

The impact of alcohol intoxication in patients admitted due to assault at an Australian major trauma centre: a trauma registry study from 1999 to 2009.

Emerg Med J 2014; 31: 390-3.

Forrester MB.

Characteristics of hand sanitizer ingestions by adolescents reported to poison centers.

Int J Adolesc Med Health 2014; online early:

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Frémont D, Berleur M-P, Mégarbane B.

Loading dose of fomepizole is safe in children with presumed toxic alcohol exposure - a case series.

Basic Clin Pharmacol Toxicol 2014; online early:

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Hayashi M, Kanda T, Nakamura M, Miyamura T, Yasui S, Nakamoto S, Wu S, Arai M, Imazeki F, Yokosuka O.

Acute liver injury in a patient with alcohol dependence: a case resembling autoimmune hepatitis or drug-induced liver injury.

Case Rep Gastroenterol 2014; 8: 129-33.

Krabseth H, Mørland J, Høiseth G.

Assistance of ethyl glucuronide and ethyl sulfate in the interpretation of postmortem ethanol findings.

Int J Legal Med 2014; online early: doi: 10.1007/s00414-014-1031-z:

Lucas BR, Latimer J, Pinto RZ, Ferreira ML, Doney R, Lau M, Jones T, Dries D, Elliott EJ.

Gross motor deficits in children prenatally exposed to alcohol: a meta-analysis.

Pediatrics 2014; 134: e192-e209.

Mainali NR, Pathak R, Aryal MR, Alweis R.

Change in mental status and recurrent hyponatremia attributable to beer potomania.


Munda SK, Khess CRJ, Bhattacharjee D, Singh NK.

Clinical manifestations of complicated alcohol withdrawal and uncomplicated alcohol withdrawal: a comparative study.

Ment Health Subst Use 2014; 7: 243-55.

Noble JM, Weimer LH.

Neurologic complications of alcoholism.


Nordt SP, Vivero LE, Rangan C.

A new clandestine route of ethanol administration? Volume of vodka absorbed in commercially available tampons. An in vitro study.


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Perry EC.

Inpatient management of acute alcohol withdrawal syndrome.

CNS Drugs 2014; 28: 401-10.

Poulos SG, Richie WD, Bailey RK, Lee A, dela Peña I, Sanberg PR, Borlongan CV.

The potential of neural stem cell transplantation for the treatment of fetal alcohol spectrum disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2014; 54C: 149-56.

29

Alcohol (ethanol)

Rambod M, Elhanafi S, Mukherjee D.

Brugada phenocopy in concomitant ethanol and heroin overdose.

Ann Noninvasive Electrocardiol 2014; online early:

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Saha D, Gottlieb S.

Hyperosmolar anion gap metabolic acidosis caused by mouth-wash.


Snyder SR, Kivlehan SM, Collopy KT.

Withdrawal and the chronic alcohol abuser. Years of drinking can cause big changes and make drying out dangerous.

EMS World 2014; 43: 44-51.

Sundström M, Jones AW, Ojanperä I.

Utility of urinary ethyl glucuronide analysis in post-mortem toxicology when investigating alcohol-related deaths.

Forensic Sci Int 2014; 241C: 178-82.

Aldehydes LoPachin RM, Gavin T.

Molecular mechanisms of aldehyde toxicity: a chemical perspective.


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Anabasine Welch KD, Lee ST, Panter KE, Gardner DR, Knoppel EL, Green BT, Hammond CK, Hammond ZJ, Pfister JA.

Studies on the teratogenicity of anabasine in a rat model.

Toxicon 2014; 87: 32-7.

Aniline Kafferlein HU, Broding HC, Bunger J, Jettkant B, Koslitz S, Lehnert M, Marek EM, Blaszkewicz M, Monse C, Weiss T, Bruning T.

Human exposure to airborne aniline and formation of methemoglobin: a contribution to occupational exposure limits.

Arch Toxicol 2014; 88: 1419-26.

Bisphenol A Corbel T, Gayrard V, Puel S, Lacroix MZ, Berrebi A, Gil S, Viguié C, Toutain P-L, Picard-Hagen N.

Bidirectional placental transfer of bisphenol A and its main metabolite, bisphenol A-glucuronide, in the isolated perfused human placenta.


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doi: 10.1016/j.reprotox.2014.06.002:

Komada M, Itoh S, Kawachi K, Kagawa N, Ikeda Y, Nagao T.

Newborn mice exposed prenatally to bisphenol A show hyperactivity and defective neocortical development.

Toxicology 2014; 323: 51-0.

Peretz J, Vrooman L, Ricke WA, Hunt PA, Ehrlich S, Hauser R, Padmanabhan V, Taylor HS, Swan SH, VandeVoort CA, Flaws JA.

Bisphenol A and reproductive health: update of experimental and human evidence, 2007-2013.


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Bromopropane Chalupka S.

Reducing workplace exposure to 1-bromopropane.

Workplace Health Saf 2014; 62: 128.

Carbon monoxide Bains S, Reid D, Huang X.

Unusual presentation of acute carbon monoxide poisoning.

Neurology 2014; 82: P6.024.

Chang S-S, Chen Y-Y, Yip PSF, Lee WJ, Hagihara A,

Gunnell D.

Regional changes in charcoal-burning suicide rates in East/Southeast Asia from 1995 to 2011: a time trend analysis.

PLoS Med 2014; 11: e1001622.

Damasio J, Garrido C, Moreira I, Neves S, Freitas J.

Chorea as an acute manifestation of carbon monoxide poisoning.

Mov Disord 2014; 29: S193.

Dogan NÖ, Savrun A, Levent S, Günaydin GP, Çelik GK, Akküçük H, Çevik Y.

Can initial lactate levels predict the severity of unintentional carbon monoxide poisoning?


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Fathallah I, Brahmi N, Nadia N, Mrad A, Amamou M.

Cardiovascular accidents during acute carbon monoxide poisoning.

Eur J Heart Fail 2014; 16: 334-5.

Geraldo AF, Silva C, Neutel D, Neto LL, Albuquerque L.

Delayed leukoencephalopathy after acute carbon monoxide intoxication.

J Radiol Case Rep 2014; 8: 1-8.

Jung Y-S, Lee J-S, Min Y-G, Park J-S, Jeon W, Park E-J, Shin J-H, Oh S, Choi S-C.

Carbon monoxide-induced cardiomyopathy – Epidemiology, clinical characteristics and prognosis –.

Circ J 2014; 78: 1437-44.

Kuroda H, Fujihara K, Kushimoto S, Aoki M.

Utility of non-conventional MRI in assessing white matter damage after carbon monoxide poisoning.

Neurology 2014; 82: P5.338.

Park E-J, Min Y-G, Kim G-W, Cho J, Maeng W, Choi S-C.

Pathophysiology of brain injuries in acute carbon monoxide poisoning: a novel hypothesis.

Med Hypotheses 2014; 83: 186-9.

Raja S, Dutta T, Kwan J.

Atypical parkinsonism following occult carbon monoxide exposure.

Neurology 2014; 82: P5.254.

30

Carbon monoxide

Senthilkumaran S, Menezes RG, Meenakshisundaram R, Thirumalaikolundusubramanian P.

Carbon monoxide poisoning and intracardiac thrombus formation: additional mechanisms.


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Shrestha R, Mourya R, Changlai BA.

Carbon monoxide poisoning: a diagnosis not to be missed!


Styles T, Przysiecki P, Archambault G, Sosa L, Toal B, Magri J, Cartter M.

Two storm-related carbon monoxide poisoning outbreaks – Connecticut, October 2011 and October 2012.

Arch Environ Occup Health 2014; online early: doi: 10.1080/19338244.2014.904267:

Carbon tetrachloride Omugba AE, Ajiboye AJ, Oyagbemi AA, Agofure E.

Modulatory effects of cod liver oil on the antioxidant status and oxidative stress induced by acute exposure to carbon tetrachloride (CCL4) in experimental animal models.

J Basic Clin Physiol Pharmacol 2014; online early: doi: 10.1515/jbcpp-2013-0143:

Corrosives Chibishev AA, Simonovska N, Bozinovska C, Pereska Z, Smokovski I, Glasnovic M.

Respiratory complications from acute corrosive poisonings in adults.

Mater Sociomed 2014; 26: 80-3.

Cosmetics Johnson W, Jr., Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Jr., Shank RC, Slaga TJ, Snyder PW, Andersen FA.

Safety assessment of chlorphenesin as used in cosmetics.

Int J Toxicol 2014; 33: 5S-15S.

Crystalline silica Aggarwal BD.

Lactate dehydrogenase as a biomarker for silica exposure-induced toxicity in agate workers.


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Lucas CD, Amft N, Reid PT.

Systemic lupus erythematosus complicating simple silicosis.

Occup Med (Oxf) 2014; online early:

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DEET Chen-Hussey V, Behrens R, Logan JG.

Assessment of methods used to determine the safety of the topical insect repellent N,N-diethyl-m-toluamide (DEET).

Parasit Vectors 2014; 7: 173.

Dichloromethane Aiso S, Take M, Kasai T, Senoh H, Umeda Y, Matsumoto M, Fukushima S.

Inhalation carcinogenicity of dichloromethane in rats and mice.

Inhal Toxicol 2014; 26: 435-51.

Diisocyanate Rüegger M, Droste D, Hofmann M, Jost M, Miedinger D.

Diisocyanate-induced asthma in Switzerland: long-term course and patients' self-assessment after a 12-year follow-up.

J Occup Med Toxicol 2014; 9: 21.

Dioxin Galimova EF, Amirova ZK, Galimov SN.

Dioxins in the semen of men with infertility.


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Tue NM, Katsura K, Suzuki G, Tuyen LH, Takasuga T, Takahashi S, Viet PH, Tanabe S.

Dioxin-related compounds in breast milk of women from Vietnamese e-waste recycling sites: levels, toxic equivalents and relevance of non-dietary exposure.

Ecotoxicol Environ Saf 2014; 106C: 220-5.

Dust Ghosh T, Gangopadhyay S, Das B.

Prevalence of respiratory symptoms and disorders among rice mill workers in India.

Environ Health Prev Med 2014; 19: 226-33.

E-cigarettes Anon.

Poison centers field increasing calls about e-cigarette exposure.

JAMA 2014; 311: 2164.

Besaratinia A, Tommasi S.

Electronic cigarettes: the road ahead.

Prev Med 2014; online early:

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Harrell PT, Simmons VN, Correa JB, Padhya TA, Brandon TH.

Electronic nicotine delivery systems ("e-cigarettes"): review of safety and smoking cessation efficacy.

Otolaryngol Head Neck Surg 2014; online early:

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Henkler F, Luch A.

E-cigarettes in Europe: does regulation swing from over-cautious to careless?

Arch Toxicol 2014; 88: 1291-4.

Hutzler C, Paschke M, Kruschinski S, Henkler F, Hahn J, Luch A.

Chemical hazards present in liquids and vapors of electronic cigarettes.

Arch Toxicol 2014; 88: 1295-308.

Miller A.

Nicotine poisoning increase due to e-cigs.

Can Med Assoc J 2014; online early:

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Nowak D, Jörres RA, Rüther T.

E-cigarettes–Prevention, pulmonary health, and addiction.

Dtsch Arztebl Int 2014; 111: 349-55.

Endocrine disrupting chemicals Jeng HA.



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Ethylene Leng G, Gries W.



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Ethylene oxide Boogaard PJ, van Puijvelde MJP, Urbanus JH.

Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.


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Formaldehyde Vilavert L, Figueras MJ, Schuhmacher M, Nadal M, Domingo JL.

Formaldehyde: a chemical of concern in the vicinity of MBT plants of municipal solid waste.

Environ Res 2014; 133C: 27-35.

Hair dye Deeb W, Cachia D, Quinn C, Salameh J.



Nelms MD, Ates G, Madden JC, Vinken M, Cronin MTD, Rogiers V, Enoch SJ.

Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes.

Arch Toxicol 2014; online early: doi: 10.1007/s00204-014-1277-8:

Hydrofluoric acid Wang X, Zhang Y, Ni L, You C, Ye C, Jiang R, Liu L, Liu J, Han C.


Burns 2014; online early:

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Hydrogen sulphide Zhang M, Deng M, Ma J, Wang X.

An evaluation of acute hydrogen sulfide poisoning in rats through serum metabolomics based on gas chro-matography-mass spectrometry.

Chem Pharm Bull 2014; 62: 505-7.

Metalworking fluids Barber CM, Burton CM, Hendrick DJ, Pickering CA, Robertson AS, Robertson W, Burge PS.

Hypersensitivity pneumonitis in workers exposed to metalworking fluids.


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Methanol Doe A, Chaunu MP, Orquevaux P, Regrain E, Tranchant C, Bakchine S.

Acute methanol intoxication: a rare cause of axial Parkinsonism.

Mov Disord 2014; 29: S107.

Hassanian-Moghaddam H, Nikfarjam A, Mirafzal A, Saberinia A, Nasehi AA, Masoumi AH, Memaryan N.

Methanol mass poisoning in Iran: role of case finding in outbreak management.

J Public Health (UK) 2014; online early:

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Mihailescu R, Bajenaru O, Copaciu E, Pop C, Ene A.

Cerebral imaging findings and neurologic outcome of methanol poisoning.

Eur J Neurol 2014; 21: 576.

Sanaei-Zadeh H.

Optical coherence tomography of the macula and optic nerve in methanol-intoxicated patients and the effect of intravenous corticosteroids on their visual disturbances.

Int Ophthalmol 2014; 34: 447-8.

Sklienka P, Neiser J, Ševcik M, Dvoracek I, Samlík J, Jonszta T, Dedek V, Kubišová MM, Tomanová R, Streitová D.

Successful kidney transplant from methanol-intoxicated donors.

Prog Transplant 2014; 24: 199-205.

Nanoparticles Fraga S, Brandão A, Soares ME, Morais T, Duarte JA, Pereira L, Soares L, Neves C, Pereira E, de Lourdes Bastos M, Carmo H.

Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration.

Nanomedicine 2014; online early:

doi: 10.1016/j.nano.2014.06.005:

Fu PP, Xia Q, Hwang H-M, Ray PC, Yu H.

Mechanisms of nanotoxicity: generation of reactive oxygen species.

J Food Drug Anal 2014; 22: 64-75.

Setyawati MI, Yuan X, Xie J, Leong DT.

The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells.

Biomaterials 2014; 35: 6707-15.

Zoroddu MA, Medici S, Ledda A, Nurchi VM, Lachowicz JI, Peana M.

Toxicity of nanoparticles.


Naphthalene Ahmed AJ.

My husband ate moth balls: methemoglobinemia and hemo-lytic anemia associated with naphthalene ingestion.


Paraffin oil Gyldenløve M, Rørvig S, Skov L, Hansen D.

Severe hypercalcaemia, nephrocalcinosis, and multiple paraffinomas caused by paraffin oil injections in a young bodybuilder.

Lancet 2014; 383: 2098.

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Perfluorinated compounds Humblet O, Diaz-Ramirez LG, Balmes JR, Pinney SM, Hiatt RA.



doi: 10.1289/ehp.1306606:

Lam J, Koustas E, Sutton P, Johnson PI, Atchley DS, Sen S, Robinson KA, Axelrad DA, Woodruff TJ.

The navigation guide-evidence-based medicine meets environmental health: integration of animal and human evidence for PFOA effects on fetal growth.


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Petrol (gasoline) and petroleum oils D'Andrea MA, Reddy GK.

Health risks associated with crude oil spill exposure.

Am J Med 2014; online early:

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Mellington FE, Bacon AS, Abu-Bakra MAJ, Martinez-Devesa P, Norris JH.

Orbital compressed air and petroleum injury mimicking necrotizing fasciitis.

J Emerg Med 2014; online early:

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Benzene Ibrahim KS, Amer NM, El-dossuky EA, Emara AM, El-Fattah AESM, Shahy EM.



Rietjens IMCM, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Marnett LJ, Smith B, Adams T, Bastaki M, Harman C, Taylor S.

The impact of structural and metabolic variation on the toxicity and carcinogenicity of hydroxy- and alkoxy- substituted allyl- and propenylbenzenes.


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Phthalate esters El-Beshbishy HA, Mariah RA, Al-Azhary NM, Aly HA, Ozbak HA, Baghdadi HH.

Influence of lipoic acid on testicular toxicity induced by bi-n-butyl phthalate in rats.

Food Chem Toxicol 2014; 71: 26-32.




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Frederiksen H, Kuiri-Hänninen T, Main KM, Dunkel L, Sankilampi U.

A longitudinal study of urinary phthalate excretion in 58 full-term and 67 preterm infants from birth through 14 months.


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Hayashi Y, Ito Y, Nakajima T.

Effects of exposure to di(2-ethylhexyl)phthalate during fetal period on next generation.

Nihon Eiseigaku Zasshi 2014; 69: 86-91.

Kay VR, Bloom MS, Foster WG. Reproductive and developmental effects of phthalate diesters in males. Crit Rev Toxicol 2014; 44: 467-98.

Kolena B, Petrovicova I, Pilka T, Pucherova Z, Munk M, Matula B, Vankova V, Petlus P, Jenisova Z, Rozova Z, Wimmerova S, Trnovec T. Phthalate exposure and health-related outcomes in specific types of work environment. Int J Environ Res Public Health 2014; 11: 5628-39.

Leng G, Koch HM, Gries W, Schütze A, Langsch A, Brüning T, Otter R.

Urinary metabolite excretion after oral dosage of bis(2-propylheptyl)phthalate (DPHP) to five male volunteers – Characterization of suitable biomarkers for human biomonitoring. Toxicol Lett 2014; online early:

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Polybrominated diphenyl ethers Chen A, Yolton K, Rauch SA, Webster GM, Hornung R, Sjödin A, Dietrich KN, Lanphear BP. Prenatal polybrominated diphenyl ether exposures and neurodevelopment in U.S. Children through 5 years of age: the HOME Study. Environ Health Perspect 2014; online early:

doi: 10.1289/ehp.1307562: Ward MH, Colt JS, Deziel NC, Whitehead TP, Reynolds P, Gunier RB, Nishioka M, Dahl GV, Rappaport SM, Buffler PA, Metayer C.

Residential levels of polybrominated diphenyl ethers and risk of childhood acute lymphoblastic leukemia in California. Environ Health Perspect 2014; online early:

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Polychlorinated biphenyls Esteban J, Elabbas LE, Borg D, Herlin M, Åkesson A, Barber X, Hamscher G, Nau H, Bowers WJ, Nakai JS, Viluksela M, Håkansson H. Gestational and lactational exposure to the polychlorinated biphenyl mixture Aroclor 1254 modulates retinoid home-ostasis in rat offspring.

Toxicol Lett 2014; 229: 41-51. Gaum PM, Esser A, Schettgen T, Gube M, Kraus T, Lang J.


Int J Hyg Environ Health 2014; online early: doi: 10.1016/j.ijheh.2014.06.001:

Quinete N, Schettgen T, Bertram J, Kraus T. Analytical approaches for the determination of PCB metabolites in blood: a review. Anal Bioanal Chem 2014; online early: doi: 10.1007/s00216-014-7922-5:

Quinete N, Schettgen T, Bertram J, Kraus T. Occurrence and distribution of PCB metabolites in blood and their potential health effects in humans: a review. Environ Sci Pollut Res 2014; online early:

doi: 10.1007/s11356-014-3136-9: Shan Q, Huang F, Wang J, Du Y.

Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice. Environ Toxicol 2014; online early: doi: 10.1002/tox.22006:

33

Polycyclic aromatic hydrocarbons Rota M, Bosetti C, Boccia S, Boffetta P, La Vecchia C.

Occupational exposures to polycyclic aromatic hydrocarbons and respiratory and urinary tract cancers: an updated systematic review and a meta-analysis to 2014.


doi: 10.1007/s00204-014-1296-5:

Polyethylene glycol Mosquera RA, McDonald M, Samuels C.


Case Rep Pediatr 2014; 2014: 872634.

Polytetrafluoroethylene Choi W-I, Jung HR, Shehu E, Rho BH, Lee M-Y, Kwon KY.

Small airway-centered granulomatosis caused by long-term exposure to polytetrafluoroethylene.

Chest 2014; 145: 1397-402.

Propylene glycol Kapitein B, Biesmans RCG, van der Sijs HI, de Wildt SN.

Propylene glycolrelated delirium after esmolol infusion.


Radiation Konkel L.

Data for disaster planning: risk factors for internal radiation exposures after Fukushima.

Environ Health Perspect 2014; 122: A166.

Radon Laborde-Castérot H, Laurier D, Caër-Lorho S, Etard C, Acker A, Rage E.

Chest X-ray screening examinations among French uranium miners: exposure estimation and impact on radon-associated lung cancer risk.


doi: 10.1136/oemed-2013-101937:

Tetrachlorodibenzodioxin Shan Q, Huang F, Wang J, Du Y.

Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyls on nonalcoholic fatty liver disease in mice.


doi: 10.1002/tox.22006:

Tobacco Da Silva FR, Kvitko K, Rohr P, Abreu MB, Thiesen FV, da Silva J.



Krautter GR, Borgerding MF.

Comparison of consumption patterns, biomarkers of exposure and subjective effects in cigarette smokers switched to dissolvable tobacco (camel orbs), dual use, or tobacco abstinence.

Nicotine Tob Res 2014; online early:

doi: 10.1093/ntr/ntu082:

Trichloroethylene Bukowski J. Critical review of the epidemiologic literature regarding the association between congenital heart defects and exposure to trichloroethylene. Crit Rev Toxicol 2014; online early:

doi: 10.3109/10408444.2014.910755: Huang P, Ren X, Huang Z, Yang X, Hong W, Zhang Y, Zhang H, Liu W, Huang H, Huang X, Wu D, Yang L, Tang H, Zhou L, Li X, Liu J. Serum proteomic analysis reveals potential serum biomarkers for occupational medicamentosa-like dermatitis caused by trichloroethylene. Toxicol Lett 2014; 229: 101-10.

Triclosan Witorsch RJ.

Critical analysis of endocrine disruptive activity of triclosan and its relevance to human exposure through the use of personal care products.


Vinyl laurate Messinger H, Bär A. Subchronic toxicity, toxicity to reproduction and prenatal developmental toxicity of vinyl laurate. Regul Toxicol Pharmacol 2014; online early: doi: 10.1016/j.yrtph.2014.06.015:

Water Hansen R. Hyponatraemic seizure in a 6-month-old infant due to water intoxication. J Paediatr Child Health 2014; online early: doi: 10.1111/jpc.12646: Hsu W-F, Wang C-C, Chen S-J, Lu Y-C, Hu C-F, Huang S-W, Wang D-S, Hsu Y-J, Fan H-C. Water intoxication induced status epilepticus in two children. J Med Sci Taiwan 2014; 34: 77-80.

Xenon Thevis M, Piper T, Geyer H, Thomas A, Schaefer MS, Kienbaum P, Schänzer W. Measuring xenon in human plasma and blood by gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom 2014; 28: 1501-6.

METALS General Bartrem C, Tirima S, von Lindern I, Von Braun M, Worrell MC, Mohammad S, Abdullahi A, Moller G. Unknown risk: co-exposure to lead and other heavy metals among children living in small-scale mining communities in Zamfara State, Nigeria. Int J Environ Health Res 2014; 24: 304-19.

Cao Y, Skaug MA, Andersen O, Aaseth J. Chelation therapy in intoxications with mercury, lead and copper. J Trace Elem Med Biol 2014; online early: doi: 10.1016/j.jtemb.2014.04.010:

Connor K, Magee B. A quantitative assessment of risks of heavy metal residues in laundered shop towels and their use by workers. Regul Toxicol Pharmacol 2014; online early: doi: 10.1016/j.yrtph.2014.06.020:

34

METALS General Júnior FB, Farina M, Viegas S, De Grava Kempinas W.

Toxicology of metals and metalloids.

BioMed Res Int 2014; 2014: 253738.

Manduca P, Naim A, Signoriello S.

Specific association of teratogen and toxicant metals in hair of newborns with congenital birth defects or developmentally premature birth in a cohort of couples with documented parental exposure to military attacks: observational study at Al Shifa Hospital, Gaza, Palestine.


Mesic A, Nefic H.

Assessment of the genotoxicity and cytotoxicity in environmentally exposed human populations to heavy metals using the cytokinesis-block micronucleus cytome assay.


doi: 10.1002/tox.22004:

Nye MD, Fry RC, Hoyo C, Murphy SK.

Investigating epigenetic effects of prenatal exposure to toxic metals in newborns: challenges and benefits.

Med Epigenet 2014; 2: 53-9.

Palacios N, Fitzgerald K, Roberts AL, Hart JE, Weisskopf MG, Schwarzschild MA, Ascherio A, Laden F.

A prospective analysis of airborne metal exposures and risk of Parkinson disease in the Nurses Health Study cohort.


doi: 10.1289/ehp.1307218:

Rana SV.

Perspectives in endocrine toxicity of heavy metals–A review.

Biol Trace Elem Res 2014; 160: 1-14.

Tvermoes BE, Banducci AM, Devlin KD, Kerger BD, Abramson MM, Bebenek IG, Monnot AD.

Screening level health risk assessment of selected metals in apple juice sold in the United States.


Waheed S, Kamal A, Malik RN.

Human health risk from organ-specific accumulation of toxic metals and response of antioxidants in edible fish species from Chenab River, Pakistan.

Environ Sci Pollut Res 2014; 21: 4409-17.

Aluminium Anon.

Pulmonary fibrosis associated with aluminum trihydrate (corian) dust.

N Engl J Med 2014; 370: 2154-7.

Donoghue AM, Coffey PS.

Health risk assessments for alumina refineries.


Donoghue AM, Frisch N, Olney D.

Bauxite mining and alumina refining: process description and occupational health risks.


Gibbs GW, Labrèche F.

Cancer risks in aluminum reduction plant workers: a review.


Kongerud J, Søyseth V.

Respiratory disorders in aluminum smelter workers.


Kvande H, Drabløs PA.

The aluminum smelting process and innovative alternative technologies.


Lidsky TI.

Is the aluminum hypothesis dead?


Mardini J, Lavergne V, Ghannoum M.

Aluminum transfer during dialysis: a systematic review.

Int Urol Nephrol 2014; online early: doi: 10.1007/s11255-014-0752-8:

Martin SC, Larivière C.

Community health risk assessment of primary aluminum smelter emissions.


Taiwo OA.

Diffuse parenchymal diseases associated with aluminum use and primary aluminum production.


Walton JR.

Chronic aluminum intake causes Alzheimer's disease: applying Sir Austin Bradford Hill's causality criteria.

J Alzheimer Dis 2014; 40: 765-838.

Wesdock JC, Arnold IMF.

Occupational and environmental health in the aluminum industry: key points for health practitioners.


Arsenic Ahmed S, Moore SE, Kippler M, Gardner R, Hawlader MDH, Wagatsuma Y, Raqib R, Vahter M.

Arsenic exposure and cell-mediated immunity in pre-school children in rural Bangladesh.



Bräuner EV, Nordsborg RB, Andersen ZJ, Tjønneland A, Loft S, Raaschou-Nielsen O.

Long-term exposure to low-level arsenic in drinking water and diabetes incidence: a prospective study of the Diet, Cancer and Health cohort.


doi: 10.1289/ehp.1408198:

Saint-Jacques N, Parker L, Brown P, Dummer TJB.

Arsenic in drinking water and urinary tract cancers: a systematic review of 30 years of epidemiological evidence.

Environ Health 2014; 13: 44.

Tsuji JS, Perez V, Garry MR, Alexander DD.

Association of low-level arsenic exposure in drinking water with cardiovascular disease: a systematic review and risk assessment.

Toxicology 2014; 323: 78-94.

Tyler CR, Allan AM.

The effects of arsenic exposure on neurological and cognitive dysfunction in human and rodent studies: a review.

Curr Environ Health Rep 2014; 1: 132-47.

35

Cadmium Bradberry SM, Wilkinson JM, Ferner RE.

Systemic toxicity related to metal hip prostheses.

Clin Toxicol 2014; online early:

doi: 10.3109/15563650.2014.944977:

Rani A, Kumar A, Lal A, Pant M.

Cellular mechanisms of cadmium-induced toxicity: a review.

Int J Environ Health Res 2014; 24: 378-99.

Wallia A, Allen NB, Badon S, Muayed ME.

Association between urinary cadmium levels and prediabetes in the NHANES 2005–2010 population.


doi: 10.1016/j.ijheh.2014.06.005:

Chromium Bradberry SM, Wilkinson JM, Ferner RE.

Systemic toxicity related to metal hip prostheses.

Clin Toxicol 2014; online early:

doi: 10.3109/15563650.2014.944977:

Copper Brewer GJ.

Alzheimer's disease causation by copper toxicity and treatment with zinc.

Front Aging Neurosci 2014; 6: 92.

Tegoni M, Valensin D, Toso L, Remelli M.

Copper chelators: chemical properties and biomedical applications.


Iron Aydinok Y, Kattamis A, Viprakasit V.


Br J Haematol 2014; 165: 745-55.

Yatmark P, Morales NP, Chaisri U, Wichaiyo S, Hemstapat W, Srichairatanakool S, Svasti S, Fucharoen S.

Iron distribution and histopathological characterization of the liver and heart of -thalassemic mice with parenteral iron overload: effects of deferoxamine and deferiprone.

Exp Toxicol Pathol 2014; 66: 333-43.

Lead Akkus C, Ozdenerol E.

Exploring childhood lead exposure through GIS: a review of the recent literature.


Bakulski KM, Park SK, Weisskopf MG, Tucker KL, Sparrow D, Spiro A, III, Vokonas PS, Nie LH, Hu H, Weuve J.

Lead exposure, B vitamins, and plasma homocysteine in men 55 years of age and older: the VA Normative Aging Study.


doi: 10.1289/ehp.1306931:

Bartrem C, Tirima S, von Lindern I, Von Braun M, Worrell MC, Mohammad S, Abdullahi A, Moller G.

Unknown risk: co-exposure to lead and other heavy metals among children living in small-scale mining communities in Zamfara State, Nigeria.

Int J Environ Health Res 2014; 24: 304-19.

Bautista AC, Puschner B, Poppenga RH.

Lead exposure from backyard chicken eggs: a public health risk?


Beaucham C, Page E, Alarcon WA, Calver GM, Methner M, Schoonover TM.

Indoor firing ranges and elevated blood lead levels – United States, 2002–2013.

MMWR Morb Mortal Wkly Rep 2014; 63: 347-51.

Chinde S, Kumari M, Devi KR, Murty US, Rahman MF, Kumari SI, Mahboob M, Grover P.



doi: 10.1007/s11356-014-3128-9:

Deeb W, Cachia D, Quinn C, Salameh J.



Getaneh Z, Mekonen S, Ambelu A.

Exposure and health risk assessment of lead in communities of Jimma town, southwestern Ethiopia.

Bull Environ Contam Toxicol 2014; online early: doi: 10.1007/s00128-014-1293-7:

Guimarãúes D, Santos JP, Carvalho ML, Diniz MS, House B, Miller VM.

Analytical evidence of heterogeneous lead accumulation in the hypothalamic defence area and nucleus tractus solitarius.

Neurotoxicology 2014; 44: 91-7.

Kahn LG, Liu X, Rajovic B, Popovac D, Oberfield S, Graziano JH, Factor-Litvak P.

Blood lead concentration and thyroid function during pregnancy: results from the Yugoslavia Prospective Study of Environmental Lead Exposure.


doi: 10.1289/ehp.1307669:

Kasperczyk A, Slowinska-LOzynska L, Dobrakowski M, Zalejska-Fiolka J, Kasperczyk S.

The effect of lead-induced oxidative stress on blood viscosity and rheological properties of erythrocytes in lead exposed humans.

Clin Hemorheol Microcirc 2014; 56: 187-95.

Kasperczyk S, Dobrakowski M, Kasperczyk A, Zalejska-Fiolka J, Pawlas N, Kapka-Skrzypczak L, Birkner E.



Kim J, Lee Y, Yang M.

Environmental exposure to lead (Pb) and variations in its susceptibility.

J Environ Sci Health [C] 2014; 32: 159-85.

Leatherwood C, Panush R.

An historical clinicopathological analysis. How Flavius Josephus, Gustav Moreau, Oscar Wilde, and Richard Strauss offer insights into the mysterious illness of King Herod.


36

Lead

Liu T, Hyson A, Langerman ST.

A case of adult lead poisoning.


Nishioka E, Yokoyama K, Matsukawa T, Vigeh M, Hirayama S, Ueno T, Miida T, Makino S, Takeda S.

Evidence that birth weight is decreased by maternal lead levels below 5g/dl in male newborns.

Reprod Toxicol 2014; 47: 21-6.

Olchowik G, Widomska J, Tomaszewski M, Gospodarek M, Tomaszewska M, Jagiello-Wójtowicz E.

The influence of lead on the biomechanical properties of bone tissue in rats.


Rao JVB, Vengamma B, Naveen T, Naveen V.

Lead encephalopathy in adults.

J Neurosci Rural Pract 2014; 5: 161-3.

Lithium Davis SS, Jr.

Clinical challenges of bariatric surgery for patients with psychiatric disorders. commentary on: "lithium toxicity following Roux-en-Y gastric bypass".

Bariatr Surg Pract Patient Care 2014; 9: 84-5.


Takotsubo cardiomyopathy associated with lithium in-toxication in bipolar disorder: a case report.


Lambe J.



doi: 10.1177/0004867414536935:

Madrigal F, Barrientos-Calvo I.

Hypernatremia in a patient with bipolar disorder treated with lithium and dural sinus thrombosis.


Morse RJ, DuBeau C.

The lithium linings playbook: competing sequelae of long-term use.


Manganese Golasik M, Wodowski G, Gomólka E, Herman M, Piekoszewski W.

Urine as a material for evaluation of exposure to manganese in methcathinone users.


doi: 10.1016/j.jtemb.2014.04.005:

Lucchini RG, Guazzetti S, Zoni S, Benedetti C, Fedrighi C, Peli M, Donna F, Bontempi E, Borgese L, Micheletti S, Ferri R, Marchetti S, Smith DR.

Neurofunctional dopaminergic impairment in elderly after lifetime exposure to manganese.


doi: 10.1016/j.neuro.2014.05.006:

Poniatowska R, Lusawa M, Skierczynska A, Makowicz G, Habrat B, Sienkiewicz-Jarosz H.

MRI brain findings in ephedrone encephalopathy associated with manganese abuse: single-center perspective.

Pol J Radiol 2014; 79: 150-5.

Selikhova MV, Tripolity E, Sanotsky Y, Matvienko Y, Staneska H, Fedorishin L, Komnatska I, Lees AJ.

Whispering dysarthria – A diagnostic hint for chronic manganese poisoning.

Mov Disord 2014; 29: S127-S128.

Mercury Basu N, Goodrich JM, Head J.

Ecogenetics of mercury: from genetic polymorphisms and epigenetics to risk assessment and decision-making.

Environ Toxicol Chem 2014; 33: 1248-58.

de Castro NSS, de Oliviera Lima M.

Biomarkers of mercury exposure in the Amazon.

BioMed Res Int 2014; 2014: 867069.

Joshi D, Kumar MD, Kumar SA, Sangeeta S.

Reversal of methylmercury-induced oxidative stress, lipid peroxidation, and DNA damage by the treatment of N-acetyl cysteine: a protective approach.

J Environ Pathol Toxicol Oncol 2014; 33: 167-82.

Li M, Wu M, Xu J, Du J, Yan C-H.

Body burden of Hg in different bio-samples of mothers in Shenyang City, China.

PLoS ONE 2014; 9: e98121.

Li Y, Ren H, Ren M, Cui F, Yang F, Chen Z, Cui L, Huang X.

Morvan syndrome plus thyroid dysfunction: a case with chronic mercury exposure.

Neurol India 2014; 62: 218-9.

Lin Y-S, Ginsberg G, Caffrey JL, Xue J, Vulimiri SV, Nath RG, Sonawane B.

Association of body burden of mercury with liver function test status in the U.S. population.

Environ Int 2014; 70C: 88-94.

Mitenko H, Bolt C.

Cup of quicksilver: the largest known single ingestion of elemental mercury.

Emerg Med Australas 2014; 26: 312-3.

Rafati-Rahimzadeh M, Rafati-Rahimzadeh M, Kazemi S, Moghadamnia AA.

Current approaches of the management of mercury poisoning: need of the hour.

Daru 2014; 22: 46.

Yorifuji T, Kato T, Kado Y, Tokinobu A, Yamakawa M, Tsuda T, Sanada S.

Intrauterine exposure to methylmercury and neurocognitive functions: Minamata disease.

Arch Environ Occup Health 2014; online early:

doi: 10.1080/19338244.2014.904268:

Yoshimasu K, Kiyohara C, Takemura S, Nakai K.

A meta-analysis of the evidence on the impact of prenatal and early infancy exposures to mercury on autism and attention deficit/hyperactivity disorder in the childhood.


doi: 10.1016/j.neuro.2014.06.007:

Silver Setyawati MI, Yuan X, Xie J, Leong DT.

The influence of lysosomal stability of silver nanomaterials on their toxicity to human cells.

Biomaterials 2014; 35: 6707-15.

37

Vanadium Li H, Lan Y. Re: Regarding letter by MacGregor and Du concerning "Vanadium exposure-induced neurobehavioral alterations among Chinese workers".

Neurotoxicology 2014; online early: doi: 10.1016/j.neuro.2014.05.008:

MacGregor JA, Du H. Re: vanadium exposure-induced neurobehavioral alterations among Chinese workers Li et al. (2013). Neurotoxicology 2014; online early:

doi: 10.1016/j.neuro.2014.05.007:

PESTICIDES General Da Silva FR, Kvitko K, Rohr P, Abreu MB, Thiesen FV, da Silva J.



Wong WWK, Yau ATC, Chung SWC, Lam C, Ma S, Ho YY, Xiao Y.

Dietary exposure of Hong Kong adults to pesticide residues: results of the first Hong Kong total diet study.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2014; 31: 852-71.

Aluminium phosphide Hussain K, Abubaker J, Ahmad DJ, Ahmed R.

Acute peripheral polyneuropathy with multiorgan failure: a diagnostic dilemma. BMJ Case Rep 2014; doi: 10.1136/bcr-2014-203989:

Jamshed N, Ekka M, Aggarwal P, Narayan S.

Severe hypoglycemia as a presenting feature of aluminum phophide poisoning.

Ann Saudi Med 2014; 34: 189.

Carbamate insecticides

Bendiocarb Holovska K, Almasiova V, Cigankova V.

Ultrastructural changes in the rabbit liver induced by carbamate insecticide bendiocarb.

J Environ Sci Health B 2014; 49: 616-23.

Herbicides

Flufenoxuron Jeong HH, Yeom SR, Han SK, Park SW.

Rapidly progressive lactic acidosis in patients with flufenoxuron poisoning.

Hong Kong J Emerg Med 2014; 21: 181-4.

Glyphosate Cassault-Meyer E, Gress S, Seralini GE, Galeraud-Denis I. An acute exposure to glyphosate-based herbicide alters aromatase levels in testis and sperm nuclear quality. Environ Toxicol Pharmacol 2014; 38: 131-40.

Mahendrakar K, Venkategowda PM, Rao SM, Mutkule DP.

Glyphosate surfactant herbicide poisoning and management.


Nishiyori Y, Nishida M, Shioda K, Suda S, Kato S. Unilateral hippocampal infarction associated with an attempted suicide: a case report. J Med Case Reports 2014; 8: 219.

Insecticides Meijer M, Dingemans MML, van den Berg M, Westerink RHS.

Inhibition of voltage-gated calcium channels as common mode of action for (mixtures of) distinct classes of insecticides.

Toxicol Sci 2014; online early: doi: 10.1093/toxsci/kfu110:

Zinc phosphide Coskun AS, Atalay C, Dagli C, Dogan N, Kürsad H.

A suicide attempt using zinc phosphide (a case study).

J Clin Anal Med 2014; 5: 65-6.

Organochlorine pesticides

General Mahmood A, Malik RN, Li J, Zhang G.

Human health risk assessment and dietary intake of organochlorine pesticides through air, soil and food crops (wheat and rice) along two tributaries of river Chenab, Pakistan.


Waliszewski SM, Caba M, Saldarriaga-Noreña H, Martínez AJ, Meza E, Valencia Quintana R, Zepeda R.

Organochlorine pesticide level differences among female inhabitants from Veracruz, Puebla and Tabasco, Mexico.

Bull Environ Contam Toxicol 2014; online early: doi: 10.1007/s00128-014-1309-3:

Wang B, Yi D, Jin L, Li Z, Liu J, Zhang Y, Qiu X, Liu W, Tao S, Ren A.

Organochlorine pesticide levels in maternal serum and risk of neural tube defects in offspring in Shanxi Province, China: a case-control study.


Organophosphorus insecticides

General Chiapella G, Genti-Raimondi S, Magnarelli G.

Placental oxidative status in rural residents environmentally exposed to organophosphates.

Environ Toxicol Pharmacol 2014; 38: 220-9.

Horn G, Wille T, Musilek K, Kuca K, Thiermann H, Worek F.

Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyryl-cholinesterase.


doi: 10.1007/s00204-014-1288-5:

Moon J, Chun B.

Utility of red blood cell acetylcholinesterase measurement in mechanically ventilated subjects after organophosphate poisoning.

Respir Care 2014; online early: doi: 10.4187/respcare.02916:

Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM.

Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface de-contamination on the percutaneous penetration of organophosphates.


doi: 10.1016/j.toxlet.2014.06.007:

Muley A, Shah C, Lakhani J, Bapna M, Mehta J.

To identify morbidity and mortality predictors in acute organophosphate poisoning.


38

Organophosphorus insecticides

General Narmadha MP, Nalini R, Ayyappan R, Murugesh N.

Analysis of organophosphates intoxication in a tertiary care hospital.

Res J Pharm Biol Chem Sci 2014; 5: 174-82.

Pereira EF, Aracava Y, DeTolla LJ, Beecham EJ, Basinger GW, Wakayama EJ, Albuquerque E.

Animal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compounds.

J Pharmacol Exp Ther 2014; online early:

doi: 10.1124/jpet.114.214932:

Sun L, Li G, Yan P, Liu Y, Li G, Wei L-Q.

Clinical management of organophosphate poisoning in pregnancy.


doi: 10.1016/j.ajem.2014.05.057:

Wang P, Wang H-P, Xu M-Y, Liang Y-J, Sun Y-J, Yang L, Li L, Li W, Wu Y-J.

Combined subchronic toxicity of dichlorvos with malathion or pirimicarb in mice liver and serum: a metabonomic study.


Chlorpyrifos Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM.


Toxicol Lett 2014; 229: 66-72.

Ozkan U, Osun A, Basarslan K, Senol S, Kaplan I, Alp H.



Williams AL, DeSesso JM.

Gestational/perinatal chlorpyrifos exposure is not associated with autistic-like behaviors in rodents.


Dichlorvos Moore CA, Wilkinson SC, Blain PG, Dunn M, Aust GA, Williams FM.


Toxicol Lett 2014; 229: 66-72.

Monocrotophos Vismaya PSR.

Oral exposure to the organophosphorus insecticide, monocrotophos induces intestinal dysfunction in rats.

Food Chem Toxicol 2014; online early:

doi: 10.1016/j.fct.2014.05.030:

Parathion Sawamoto K, Loro E, Krajacic P, Gaspari R, Khurana T, Bird SB.

Timecourse of neuromuscular junction failure after acute parathion poisoning.


Paraquat and diquat Blanco-Ayala T, Andérica-Romero AC, Pedraza-Chaverri J.

New insights into antioxidant strategies against paraquat toxicity.

Free Radic Res 2014; 48: 623-40.


Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neuro-toxicity.

Toxicol Lett 2014; 228: 179-91.

Sun IO, Yoon HJ, Kim JG, Lee KY.

Predicting the probability of survival in acute paraquat poisoning.

Nephrol Dial Transplant 2014; 29: iii362-iii363.

Yu GC, Kan BT, Jian XD, Wang J, Sun J, Song CZ.

A case report of acute severe paraquat poisoning and long-term follow-up.

Exp Ther Med 2014; 8: 233-6.

Pyrethroid insecticides

General Zhang J, Yoshinaga J, Hisada A, Shiraishi H, Shimodaira K, Okai T, Koyama M, Watanabe N, Suzuki E, Shirakawa M, Noda Y, Komine Y, Ariki N, Kato N.

Prenatal pyrethroid insecticide exposure and thyroid hormone levels and birth sizes of neonates.

Sci Total Environ 2014; 488-489: 275-9.

CHEMICAL WARFARE,

BIOLOGICAL WARFARE AND RIOT CONTROL AGENTS Biological warfare Pitschmann V.

Overall view of chemical and biochemical weapons.

Toxins 2014; 6: 1761-84.

Chemical warfare

General Pitschmann V.

Overall view of chemical and biochemical weapons.

Toxins 2014; 6: 1761-84.

Mustard gas Shohrati M, Haji R, Esfandiari MA, Najafian N, Najafian B, Golbedagh A.

Serum matrix metalloproteinase levels in patients exposed to sulfur mustard.

Iran Red Crescent Med J 2014; 16: e15129.

Nerve agents

Tabun Lo R, Ganguly B.

Can hydroxylamine be a more potent nucleophile for the reactivation of tabun-inhibited AChE than prototype oxime drugs? An answer derived from quantum chemical and steered molecular dynamics studies.

Mol Biosyst 2014; online early:

doi: 10.1039/c4mb00083h:

39

PLANTS General Glover R, Patterson D, Connors N, Smith S, Milstein M, Swerdlow M.

Electrophysiological findings in acute solanum torvum toxicity.

Neurology 2014; 82: P5.103.

Lee JS, Kim Y-H, Kim D-B, Bang W-S, Lee O-H.

Acute and 4-week repeated-dose oral toxicity studies of Cirsium setidens in rats.

Molecules 2014; 19: 7138-51.

Amanita mushrooms Frass M, Zagorchev P, Yurukova V, Wulkersdorfer B, Thieves K, Zedtwitz-Liebenstein K, Bursch W, Kaye AD.

Two cases of fulminant hepatic failure from Amanita phalloides poisoning treated additively by homeopathy.

Ochsner J 2014; 14: 252-8.

Yilmaz I, Kaya E, Sinirlioglu ZA, Bayram R, Surmen MG, Colakoglu S.

Clinical importance of toxin concentration in Amanita verna mushroom.

Toxicon 2014; 87: 68-75.

Cascabela thevetia (Yellow oleander) Fentanes E.

Eating seeds from the 'be still' tree, yet having lucky nut poisoning: a case of acute yellow oleander poisoning.


Cirsium setidens (Thistle) Lee JS, Kim Y-H, Kim D-B, Bang W-S, Lee O-H.

Acute and 4-week repeated-dose oral toxicity studies of Cirsium setidens in rats.

Molecules 2014; 19: 7138-51.

Datura stramonium (Jimson weed) Rakotomavo F, Andriamasy C, Rasamoelina N, Raveloson N.

Datura stramonium intoxication in two children.

Pediatr Int 2014; 56: e14-e16.

Myristica fragrans (Nutmeg) Sivathanu S, Sampath S, David HS, Rajavelu KK.

Myristicin and phenytoin toxicity in an infant.


Peganum harmala (Esfand) Berdai MA, Labib S, Harandou M.

Peganum harmala L. intoxication in a pregnant woman.

Case Rep Emerg Med 2014; 2014: 783236.

Solanum torvum (Susumber berry) Glover R, Patterson D, Connors N, Smith S, Milstein M, Swerdlow M.

Electrophysiological findings in acute solanum torvum toxicity.

Neurology 2014; 82: P5.103.

Toxicodendron radicans (Poison ivy) Mcclanahan C, Asarch A, Swick BL.

Black spot poison ivy.

Int J Dermatol 2014; 53: 752-3.

ANIMALS Bee sting Dhaliwal J. National estimates of noncanine bite and sting injuries treated in United States hospital emergency departments, 20012010: Langley R, Mack K, Haileyesus T, Proescholdbell

S, Annest JL. Wilderness Environ Med 2014;25:1423. J Emerg Med 2014; 46: 875.

Unal E, Balta I, Bozkurt O. Lichen striatus: after a bite by bumblebee. Cutan Ocul Toxicol 2014; online early: doi: 10.3109/15569527.2014.910804:

Fish/marine poisoning Ciguatera Bailey S, Withers T. Ciguatera poisoning in the Cook Islands. BMJ Case Rep 2014; doi: 10.1136/bcr-2014-204847: Barrett JR. Under the weather with ciguatera fish poisoning: climate variables associated with increases in suspected cases. Environ Health Perspect 2014; 122: A167.

Jadeja N, Haider A, Gottesman R, Kozicky M, Nafday A, Kelson K, Jinjolava N. A case of ciguatera poisoning in a New York City Hospital: learning points for Hospitals serving diverse immigrant populations. Neurology 2014; 82: P2.328. Morales M, Neves Cardoso M, Cabib C, Rolón JI, Araújo Mota I, Valls-Solé J. Abnormal subclinical thermal sensory perception in 3 cases of ciguatera intoxication. Eur J Neurol 2014; 21: 224. Sundaram AK, Grimes J, Samani S, Roy C. Nausea, vomiting and diarrhea: common symptoms with an uncommon etiology. J Gen Intern Med 2014; 29: S391.

Millipede Heeren Neto AS, Bernardes FF, Martins G. Skin lesions simulating blue toe syndrome caused by prolonged contact with a millipede. Rev Soc Bras Med Trop 2014; 47: 257-8.

Scorpions Oukkache N, Jaoudi RE, Ghalim N, Chgoury F, Bouhaouala B, Mdaghri NE, Sabatier J-M. Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes. Toxins (Basel) 2014; 6: 1873-81. Prakash V, Krishnamurthy S, Mahadevan S, Bethou A, Barathi SD. Infective endocarditis and septic pulmonary embolism following scorpion sting envenoming in an 11-year-old child. Paediatr Int Child Health 2014; 34: 145-7. Yardehnavi N, Behdani M, Pooshang BK, Mahmoodzadeh A, Khanahmad H, Shahbazzadeh D, Habibi-Anbouhi M, Ghassabeh GH, Muyldermans S. A camelid antibody candidate for development of a therapeutic agent against Hemiscorpius lepturus en-venomation. FASEB J 2014; online early: doi: 10.1096/fj.13-247478:

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Snake bites Al Asmari AK, Khan HA, Manthiri RA, Al Yahya KM, Al Otaibi KE. Effects of Echis pyramidum snake venom on hepatic and renal antioxidant enzymes and lipid peroxidation in rats. J Biochem Mol Toxicol 2014; online early: doi: 10.1002/jbt.21578: Chiew AL, Isbister GK. A coagulopathic dilemma: snakes or genes. Lancet 2014; 383: 2184. Correa JA, Fallon SC, Cruz AT, Grawe GH, Vu PV, Rubalcava DM, Kaziny B, Naik-Mathuria BJ, Brandt ML. Management of pediatric snake bites: are we doing too much? J Pediatr Surg 2014; 49: 1009-15. Oukkache N, Jaoudi RE, Ghalim N, Chgoury F, Bouhaouala B, Mdaghri NE, Sabatier J-M. Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes. Toxins (Basel) 2014; 6: 1873-81. Shahidi Bonjar L. Design of a new therapy to treat snake envenomation. Drug Des Devel Ther 2014; 8: 819-25. Theakston RDG, Laing GD. Diagnosis of snakebite and the importance of immunological tests in venom research. Toxins (Basel) 2014; 6: 1667-95.

Cobra Asad MHHB, Murtaza G, Ubaid M, Durr-e-Sabih, Sajjad A, Mehmood R, Mahmood Q, Ansari MM, Karim S, Mehmood Z, Hussain I. Naja naja karachiensis envenomation: biochemical param-eters for cardiac, liver, and renal damage along with their neutralization by medicinal plants. BioMed Res Int 2014; 2014: 970540. Yap MK, Tan NH, Sim SM, Fung SY, Tan CH. Pharmacokinetics of Naja sumatrana (Equatorial Spitting Cobra) venom and its major toxins in experimentally envenomed rabbits. PLoS Negl Trop Dis 2014; 8: e2890.

Crotalinae (Pit vipers) Bush SP, Mooy GG, Phan TH. Catastrophic acute ischemic stroke after Crotalidae polyvalent immune Fab (ovine)-treated rattlesnake envenomation. Wilderness Environ Med 2014; 25: 198-203. Dixon J. A retrospective review of early gastrointestinal symptoms in the prediction of crotaline envenomation severity: Thornton SL, Nguyen KT, Shenn SK, Castillo EM, Clark RF, Cantrell FL. Wilderness Environ Med 2012;23:360-2. J Emerg Med 2014; 46: 877. Guimarães CL, Andriao-Escarso SH, Moreira-Dill LS, Carvalho BM, Marchi-Salvador DP, Santos-Filho NA, Fernandes CA, Fontes MR, Giglio JR, Barraviera B, Zuliani JP, Fernandes CF, Calderón LA, Stábeli RG, Albericio F, da Silva SL, Soares AM. Alkylation of histidine residues of Bothrops jararacussu venom proteins and isolated phospholipases A2: a biotechnological tool to improve the production of antibodies. BioMed Res Int 2014; 2014: 981923. Laines J, Segura Á, Villalta M, Herrera M, Vargas M, Alvarez G, Gutiérrez JM, León G. Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica. Toxicon 2014; 88: 34-7.

Viperinae (True vipers) Shivanthan MC, Yudhishdran J, Navinan R, Rajapakse S. Hump-nosed viper bite: an important but under-recognized cause of systemic envenoming. J Venom Anim Toxins Incl Trop Dis 2014; 20: 24.

Spiders White J, Weinstein SA. A phoenix of clinical toxinology: white-tailed spider (Lampona spp.) bites. a case report and review of medical significance. Toxicon 2014; 87: 76-80.

INDEX Acetaminophen .................................................................. 25 Acetylcysteine .................................................................... 17 Acrylonitrile ....................................................................... 28 Air pollution ....................................................................... 26 Alcohol .............................................................................. 28 Aldehydes .......................................................................... 29 Aluminium ......................................................................... 34 Aluminium phosphide ......................................................... 37 Amanita mushrooms .......................................................... 39 Amfetamines ..................................................................... 19 Amiodarone ....................................................................... 19 Anabasine ......................................................................... 29 Anabolic steroids ................................................................ 19 Anaesthetics ...................................................................... 19 Analytical toxicology ............................................................ 4 Aniline ............................................................................... 29 Animals, general ................................................................ 39 Anthracyclines ................................................................... 22

Antiarrhythmics ................................................................. 19 Antibiotics ......................................................................... 19 Anticholinergic drugs ......................................................... 19 Anticoagulants................................................................... 20 Anticonvulsants ................................................................. 20 Antidepressants ................................................................. 20 Antidotes .......................................................................... 16 Antifungal drugs ................................................................ 20 Antihistamines ................................................................... 20 Antineoplastics .................................................................. 20 Antipsychotics ................................................................... 20 Antituberculous drugs ........................................................ 20 Antivenom ........................................................................ 17 Antiviral drugs ................................................................... 20 Arprinocid ......................................................................... 26 Arsenic ............................................................................. 34 Ascorbic acid ..................................................................... 17 Azithromycin ..................................................................... 19

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Baclofen ............................................................................ 21 Barbiturates ....................................................................... 21 Bee sting ........................................................................... 39 Bendiocarb ........................................................................ 37 Benzene ............................................................................ 32 Benzodiazepines ................................................................ 21 Beta blockers ..................................................................... 21 Beta-hydroxybutyrate ......................................................... 21 Biological warfare............................................................... 38 Biomarkers ......................................................................... 5 Bisphenol A ....................................................................... 29 Bromopropane ................................................................... 29 Bupivacaine ....................................................................... 19 Buprenorphine ................................................................... 25 Cadmium ........................................................................... 35 Caffeic acid phenethyl ester ................................................ 17 Caffeine............................................................................. 21 Calciferol ........................................................................... 26 Calcium carbonate ............................................................. 21 Calcium channel blockers.................................................... 21 Cannabis ........................................................................... 21 Carbamate insecticides ....................................................... 37 Carbon monoxide ............................................................... 29 Carbon tetrachloride ........................................................... 30 Carcinogenicity ................................................................... 5 Cardiotoxicity ...................................................................... 5 Cascabela thevetia ............................................................. 39 Cefozopran ........................................................................ 19 Chelating agents ................................................................ 17 Chemical incidents ............................................................. 27 Chemical warfare, general .................................................. 38 Chemicals, general ............................................................. 28 Chlorphenesin .................................................................... 20 Chlorpyrifos ....................................................................... 38 Cholecalciferol ................................................................... 26 Chromium ......................................................................... 35 Ciguatera .......................................................................... 39 Cirsium setidens................................................................. 39 Cisplatin ............................................................................ 20 Cobra ................................................................................ 40 Cocaine ............................................................................. 22 Copper .............................................................................. 35 Corrosives ......................................................................... 30 Cosmetics .......................................................................... 30 Crotalinae .......................................................................... 40 Crystalline silica ................................................................. 30 Cytotoxic drugs .................................................................. 22 Dabigatran ........................................................................ 20 Datura stramonium ............................................................ 39 DEET ................................................................................. 30 Dermal toxicity.................................................................... 6 Developmental toxicology .................................................... 6 Dexmedetomidine .............................................................. 17 Diacetylmorphine ............................................................... 23 Dichloromethane ................................................................ 30 Dichlorvos ......................................................................... 38 Diclofenac ......................................................................... 24 Dietary supplements .......................................................... 23 Digoxin .............................................................................. 22 Diisocyanate ...................................................................... 30 Diltiazem ........................................................................... 21 Dioxin ............................................................................... 30 Diphenhydramine ............................................................... 20 Diquat ............................................................................... 38 Disulfiram .......................................................................... 17 Driving under the influence .................................................. 7 Dronedarone ..................................................................... 19 Drugs, general ................................................................... 18 Dust .................................................................................. 30 E-cigarettes ....................................................................... 30 Ecstasy .............................................................................. 19 Efavirenz ........................................................................... 20

Endocrine disrupting chemicals ........................................... 30 Endostatin ......................................................................... 22 Ephedrone ........................................................................ 22 Epidemiology....................................................................... 8 Escitalopram ..................................................................... 25 Esfand .............................................................................. 39 Ethambutol ....................................................................... 20 Ethanol ............................................................................. 28 Ethnic remedies ................................................................. 23 Ethylene ........................................................................... 31 Ethylene oxide................................................................... 31 Exhaust fumes .................................................................. 27 Extracorporeal treatments .................................................. 17 Fentanyl............................................................................ 25 Fish/marine poisoning ........................................................ 39 Flufenoxuron ..................................................................... 37 Fluorouracil ....................................................................... 22 Fomepizole........................................................................ 17 Foreign body ingestion ......................................................... 9 Forensic toxicology .............................................................. 9 Formaldehyde ................................................................... 31 Gamma hydroxybutyrate .................................................... 22 Gasoline ............................................................................ 32 Genotoxicity ........................................................................ 9 Glyphosate ........................................................................ 37 Haemodiafiltration ............................................................. 17 Hair dye ............................................................................ 31 Hazardous waste ............................................................... 27 Hepatotoxicity ................................................................... 10 Herbal medicines ............................................................... 23 Herbicides ......................................................................... 37 Heroin .............................................................................. 23 Hydrofluoric acid ............................................................... 31 Hydrogen sulphide ............................................................. 31 Hydroxylamine .................................................................. 17 Hypoglycaemics ................................................................. 23 Immunosuppressants ........................................................ 23 Inhalation toxicity .............................................................. 10 Insecticides ....................................................................... 37 Insulin .............................................................................. 23 Iron .................................................................................. 35 Isoproterenol .................................................................... 23 Isotretinoin ....................................................................... 23 Jimson weed ..................................................................... 39 Khat ................................................................................. 23 Krokodil ............................................................................ 23 Lamotrigine ....................................................................... 20 Lead ................................................................................. 35 Levetiracetam ................................................................... 20 Lipid emulsion therapy ....................................................... 17 Lithium ....................................................................... 23, 36 Management, general ........................................................ 16 Manganese ....................................................................... 36 Marijuana .......................................................................... 21 MDMA ............................................................................... 19 Mechanisms ...................................................................... 10 Medication errors ............................................................... 11 Mephedrone ...................................................................... 24 Mercury ............................................................................ 36 Metals, general .................................................................. 33 Metalworking fluids ............................................................ 31 Metformin ......................................................................... 23 Methadone ........................................................................ 24 Methanol........................................................................... 31 Methcathinone .................................................................. 24 Methotrexate ..................................................................... 22 Methoxetamine ................................................................. 24 Methylene blue .................................................................. 17 Methylthioninium chloride .................................................. 17 Metronidazole .................................................................... 19 Millipede ........................................................................... 39 Mitoxantrone ..................................................................... 24

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Current Awareness in Clinical Toxicology is produced monthly for the American

Academy of Clinical Toxicology by the Birmingham Unit of the UK National Poisons

Information Service, with contributions from the Cardiff, Edinburgh, and Newcastle

Units.

The NPIS is commissioned by Public Health England

Monocrotophos .................................................................. 38 Morphine ........................................................................... 25 Mustard gas ....................................................................... 38 Mycophenolate .................................................................. 23 Myristica fragrans .............................................................. 39 Naloxone ........................................................................... 17 Nanoparticles ..................................................................... 31 Naphthalene ...................................................................... 31 Nephrotoxicity ................................................................... 11 Nerve agents ..................................................................... 38 Neurotoxicity ..................................................................... 11 Nicotine ............................................................................. 24 NSAIDs ............................................................................. 24 Nutmeg ............................................................................. 39 Occupational toxicology ...................................................... 12 Opioids .............................................................................. 24 Organochlorine pesticides, general ...................................... 37 Organophosphorus insecticides, general .............................. 37 Orphenadrine .................................................................... 19 Oximes .............................................................................. 17 Paediatric toxicology .......................................................... 13 Paracetamol ...................................................................... 25 Paraffin oil ......................................................................... 31 Paraquat ........................................................................... 38 Parathion ........................................................................... 38 Peganum harmala .............................................................. 39 Pentobarbital ..................................................................... 21 Perfluorinated compounds .................................................. 32 Pesticides, general ............................................................. 37 Petrol ................................................................................ 32 Phenytoin .......................................................................... 20 Phthalate esters ................................................................. 32 Pit vipers ........................................................................... 40 Plants, general ................................................................... 39 Poison information centres ................................................. 15 Poison ivy .......................................................................... 39 Poisons information ............................................................ 15 Pollution ............................................................................ 27 Polybrominated diphenyl ethers .......................................... 32 Polychlorinated biphenyls ................................................... 32 Polycyclic aromatic hydrocarbons ........................................ 33 Polyethylene glycol............................................................. 33 Polymorphisms .................................................................. 15 Polytetrafluoroethylene ...................................................... 33 Propranolol ........................................................................ 21 Propylene glycol ................................................................. 33

Psilocybin .......................................................................... 25 Psychiatric aspects ............................................................ 15 Psychotropic drugs ............................................................ 25 Pyrethroid insecticides, general .......................................... 38 Radiation .......................................................................... 33 Radon ............................................................................... 33 Reprotoxicity ..................................................................... 15 Risk assessment ................................................................ 15 Scorpions .......................................................................... 39 Sertraline .......................................................................... 25 Silver ................................................................................ 36 Snake bites ....................................................................... 40 Sodium nitrate .................................................................. 25 Solanum torvum ................................................................ 39 Spiders ............................................................................. 40 SSRIs................................................................................ 25 Statins .............................................................................. 25 Stimulant drugs ................................................................. 25 Substance abuse ............................................................... 25 Suicide .............................................................................. 16 Susumber berry ................................................................. 39 Tabun ............................................................................... 38 Tamoxifen ......................................................................... 26 Tetrachlorodibenzodioxin ................................................... 33 Thalidomide ...................................................................... 26 Thistle .............................................................................. 39 Tobacco ............................................................................ 33 Toxicodendron radicans ..................................................... 39 Toxicology, general ............................................................. 4 Trichloroethylene ............................................................... 33 Triclosan ........................................................................... 33 True vipers........................................................................ 40 Valproate .......................................................................... 20 Valsartan .......................................................................... 26 Vanadium ......................................................................... 37 Verapamil ......................................................................... 21 Veterinary products ........................................................... 26 Vinyl laurate ...................................................................... 33 Viperinae .......................................................................... 40 Vitamins............................................................................ 26 Water ............................................................................... 33 Water pollution .................................................................. 28 Xenon ............................................................................... 33 Yellow oleander ................................................................. 39 Zinc phosphide .................................................................. 37

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