Journal articles Thorax November 2014, Volume 69, Issue 11

Editorials

Emphysema: time to say farewell to therapeutic nihilism Zaid Zoumot, Simon Jordan, Nicholas S Hopkinson Thorax 2014;69:973-975 [Extract]

The child is father of the man: the importance of early life influences on lung development A John Henderson Thorax 2014;69:976-977 [Extract] Antioxidants and respiratory disease: the uric acid paradox Seif O Shaheen Thorax 2014;69:978-979 [Extract]

Chronic obstructive pulmonary disease

Original article: Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial Gaëtan Deslee, Karin Klooster, Martin Hetzel, et al. Thorax 2014;69:980-986 [Abstract][Full text][PDF][Request permissions]

Original article: Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS) Benjamin M Smith, Eric A Hoffman, Dan Rabinowitz, et al.

Current Awareness Bulletin

Respiratory Medicine

November 2014

Thorax 2014;69:987-996 [Abstract]

Environmental exposure

Original article: Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts Yutong Cai, Tamara Schikowski, Martin Adam, et al. Thorax 2014;69:1005-1014 [Abstract]

Respiratory epidemiology

Original article: Serum uric acid and the risk of respiratory disease: a population-based cohort study Laura J Horsfall, Irwin Nazareth, Irene Petersen Thorax 2014;69:1021-1026 [Abstract][Full text][PDF][Supplementary Data][Request permissions]

FREE Original article: Coarse particulate matter associated with increased risk of emergency hospital admissions for pneumonia in Hong Kong Hong Qiu, Lin Wei Tian, Vivian C Pun, Kin-fai Ho, Tze Wai Wong, Ignatius T S Yu Thorax 2014;69:1027-1033 [Abstract]

Research letters

Heterogeneity's ruses: the neglected role of between-individual variability in longitudinal studies of COPD exacerbations Mohsen Sadatsafavi, J Mark FitzGerald Thorax 2014;69:1043-1044 [Abstract][Full text][PDF][Supplementary Data][Request permissions]

Positional oximetry to screen for pulmonary arteriovenous malformations in HHT Susan Carpenter, Janina Josepovici, Giuseppe Latino, Felix Ratjen Thorax 2014;69:1045 [Abstract] Orthodeoxia and postural orthostatic tachycardia in patients with pulmonary arteriovenous malformations: a prospective 8-year series V Santhirapala, B Chamali, H McKernan, et al. Thorax 2014;69:1046-1047 [Abstract]

Chest clinic

Audit, research and guideline update: Cochrane corner: is integrated disease management for patients with COPD effective? Annemarije L Kruis, Nynke Smidt, Willem J J Assendelft, et al. Thorax 2014;69:1053-1055 [Abstract][Full text][PDF][Request permissions]

Audit, research and guideline update: Changes to inhaled corticosteroid dose when initiating combination inhaler therapy in long-acting β agonist-naïve patients with asthma: a retrospective database analysis Jordan R Covvey, Blair F Johnston, Fraser Wood, Anne C Boyter Thorax 2014;69:1056-1058 [Abstract]

Case based discussion

Lesson of the month: extrinsic allergic (bronchiolo)alveolitis and metal working fluids Paul Cullinan, Eva D'Souza, Rachel Tennant, Chris Barber Thorax 2014;69:1059-1060 [Extract][Full text][PDF][Request permissions]

Images in thorax: Intrapulmonary lipomatosis Chao-Yu Liu, Yu-Chao Yu, Chih-Cheng Hsieh, Yeh-Han Wang, Teh-Ying Chou Thorax 2014;69:1061-1062 [Extract]

American Journal of Respiratory and Critical Care Medicine Volume 190, Issue 9 (November 1, 2014)

Chronic Obstructive Pulmonary Disease: Different Risk Factors and Different Natural Histories? Jørgen Vestbo, and Bartolome Celli American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 968-970. http://www.atsjournals.org/doi/abs/10.1164/rccm.201409-1705ED?ai=s0&ui=1ytu&af=T Expanding the Dimensions of Effectiveness Research in Sepsis Allan J. Walkey American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 970-971. http://www.atsjournals.org/doi/abs/10.1164/rccm.201409-1710ED?ai=s0&ui=1ytu&af=T Body Composition, Lung Transplant Candidacy, and Patient Outcomes Roger D. Yusen American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 971-973. http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1767ED?ai=s0&ui=1ytu&af=T Is Pulmonary Hypertension a Metabolic Disease? Jarrod Barnes, and Raed A. Dweik American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 973-975. http://www.atsjournals.org/doi/abs/10.1164/rccm.201409-1702ED?ai=s0&ui=1ytu&af=T Training Pulmonary Researchers to Span the Bench-to-Bedside “Valley of Death” Mark T. Gladwin and Christopher P. O’Donnell American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 977-980. http://www.atsjournals.org/doi/abs/10.1164/rccm.201405-0822ED?ai=s0&ui=1ytu&af=T Network Analysis in the Investigation of Chronic Respiratory Diseases. From Basics to Application Diego Diez, Alvar Agustí, and Craig E. Wheelock American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 981-988. http://www.atsjournals.org/doi/abs/10.1164/rccm.201403-0421PP?ai=s0&ui=1ytu&af=T Multicenter Study Comparing Case Definitions Used to Identify Patients with Chronic Obstructive Pulmonary Disease Valentin Prieto-Centurion, Andrew J. Rolle, David H Au, et al. on behalf of the CONCERT Consortium American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 989-995.

http://www.atsjournals.org/doi/abs/10.1164/rccm.201406-1166OC?ai=s0&ui=1ytu&af=T FEV1 Decline in Patients with Chronic Obstructive Pulmonary Disease Associated with Biomass Exposure Alejandra Ramírez-Venegas, Raul H. Sansores, Roger H. Quintana-Carrillo, et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 996-1002. http://www.atsjournals.org/doi/abs/10.1164/rccm.201404-0720OC?ai=s0&ui=1ytu&af=T Body Composition and Mortality after Adult Lung Transplantation in the United States Jonathan P. Singer, Eric R. Peterson, Mark E. Snyder, et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 1012-1021. http://www.atsjournals.org/doi/abs/10.1164/rccm.201405-0973OC?ai=s0&ui=1ytu&af=T Interleukin-26 in Antibacterial Host Defense of Human Lungs. Effects on Neutrophil Mobilization Karlhans F. Che, Sara Tengvall, Bettina Levänen, et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 1022-1031. http://www.atsjournals.org/doi/abs/10.1164/rccm.201404-0689OC?ai=s0&ui=1ytu&af=T Risk of Tuberculosis after Recent Exposure. A 10-Year Follow-up Study of Contacts in Amsterdam Rosa Sloot, Maarten F. Schim van der Loeff, Peter M. Kouw, and Martien W. Borgdorff American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 1044-1052. http://www.atsjournals.org/doi/abs/10.1164/rccm.201406-1159OC?ai=s0&ui=1ytu&af=T Unilateral Pulmonary Fibrosis and Systemic Sclerosis Viktor N. Lesnyak, Olesya V. Danilevskaya, Alexander V. Averyanov et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 1067-1068. http://www.atsjournals.org/doi/abs/10.1164/rccm.201407-1253IM?ai=s0&ui=1ytu&af=T Primary Pulmonary Lymphoma Presenting with Multiple Lung Nodules Koichiro Shinoda, Hirofumi Taki, Takeshi Tsuda, Ryuji Hayashi, Kazuhiro Nomoto, and Kazuyuki Tobe American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: e30-e31. http://www.atsjournals.org/doi/abs/10.1164/rccm.201401-0086IM?ai=s0&ui=1ytu&af=T Kommerell Diverticulum Compressing the Tracheobronchial Tree and Presenting as Wheezing Chung-Ting Chen, Chia-Ming Chang, and Hsien-Hao Huang American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: e32-e33. http://www.atsjournals.org/doi/abs/10.1164/rccm.201403-0440IM?ai=s0&ui=1ytu&af=T Targeting B Lymphocytes in Progressive Fibrosing Mediastinitis Blair D. Westerly, Geoffrey B. Johnson, Fabien Maldonado, et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 9: 1069-1071. http://www.atsjournals.org/doi/abs/10.1164/rccm.201407-1258LE?ai=s0&ui=1ytu&af=T

American Journal of Respiratory and Critical Care Medicine Volume 190, Issue 10 (November 15, 2014)

Bringing in the Cavalry: IL-26 Mediates Neutrophil Recruitment to the Lungs Kristin L. Griffiths, and Shabaana A. Khader, American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1079-1080. http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1870ED?ai=s0&ui=1ytu&af=T Narrowing in on Early Cystic Fibrosis Lung Disease Edith T. Zemanick, Lucas Hoffman, and Margaret Rosenfeld American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1082-1084. http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1929ED?ai=s0&ui=1ytu&af=T MARCKS Is Marked in Combating Lung Cancer Growth and Acquired Resistance Sekhar P. Reddy, Viswanathan Natarajan, and Arkadiusz Z. Dudek

American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1084-1086. http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1922ED?ai=s0&ui=1ytu&af=T REM Sleep: A Nightmare for Patients with Obstructive Sleep Apnea? Yüksel Peker, American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1088-1090. http://www.atsjournals.org/doi/abs/10.1164/rccm.201410-1897ED?ai=s0&ui=1ytu&af=T Acute Respiratory Distress Syndrome: Emerging Research in China Yuanlin Song, Feng Xu, Eric J. Seeley, Jiaxian Ou, Xiaodan Zhu, Ruijuan Sun, and Chunxue Bai American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1090-1093. http://www.atsjournals.org/doi/abs/10.1164/rccm.201407-1392ED?ai=s0&ui=1ytu&af=T IL-17 in Severe Asthma. Where Do We Stand? Julie Chesné, Faouzi Braza, Guillaume Mahay, Sophie Brouard, Marc Aronica, and Antoine Magnan American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1094-1101. http://www.atsjournals.org/doi/abs/10.1164/rccm.201405-0859PP?ai=s0&ui=1ytu&af=T Targeting Myristoylated Alanine-Rich C Kinase Substrate Phosphorylation Site Domain in Lung Cancer. Mechanisms and Therapeutic Implications Ching-Hsien Chen, Sarah Statt, Chun-Lung Chiu American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1127-1138. http://www.atsjournals.org/doi/abs/10.1164/rccm.201408-1505OC?ai=s0&ui=1ytu&af=T α-Hemolysin Activity of Methicillin-Susceptible Staphylococcus aureus Predicts Ventilator-associated Pneumonia Lukas Stulik, Stefan Malafa, Jana Hudcova American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1139-1148. http://www.atsjournals.org/doi/abs/10.1164/rccm.201406-1012OC?ai=s0&ui=1ytu&af=T Obstructive Sleep Apnea during REM Sleep and Hypertension. Results of the Wisconsin Sleep Cohort Babak Mokhlesi, Laurel A. Finn, Erika W. Hagen, et al. American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1158-1167. http://www.atsjournals.org/doi/abs/10.1164/rccm.201406-1136OC?ai=s0&ui=1ytu&af=T Risk Assessment of Tuberculosis in Immunocompromised Patients. A TBNET Study Martina Sester, Frank van Leth, Judith Bruchfeld, et al., for the TBNET|| American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1168-1176. http://www.atsjournals.org/doi/abs/10.1164/rccm.201405-0967OC?ai=s0&ui=1ytu&af=T An Official American Thoracic Society Statement: Diagnosis and Management of Beryllium Sensitivity and Chronic Beryllium Disease John R. Balmes, Jerrold L. Abraham, Raed A. Dweik, et al.; on behalf of the ATS Ad Hoc Committee on Beryllium Sensitivity and Chronic Beryllium Disease American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: e34-e59. http://www.atsjournals.org/doi/abs/10.1164/rccm.201409-1722ST?ai=s0&ui=1ytu&af=T Getting a Better Picture of the Correlation between Lung Function and Structure Using Electrical Impedance Tomography Claude Guerin, and Inéz Frerichs American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: 1186-1187. http://www.atsjournals.org/doi/abs/10.1164/rccm.201405-0812IM?ai=s0&ui=1ytu&af=T Cerebral Air Embolism. A Case of Disseminated Klebsiella pneumoniae Infection Jehan Alladina, Daniela Lamas, and Josalyn Cho American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: e60-e61. http://www.atsjournals.org/doi/abs/10.1164/rccm.201403-0594IM?ai=s0&ui=1ytu&af=T Sarcoid-Like Reaction in Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Lioudmila V. Karnatovskaia, Andras Khoor, and Isabel Mira-Avendano American Journal of Respiratory and Critical Care Medicine, Vol. 190, No. 10: e62-e63. http://www.atsjournals.org/doi/abs/10.1164/rccm.201403-0513IM?ai=s0&ui=1ytu&af=T

European Respiratory Journal November 1, 2014; 44 (5)

Editorials

Cough hypersensitivity syndrome: towards a new approach to chronic cough Roger Escamilla and Nicolas Roche Eur Respir J 2014 44:1103-1106 http://erj.ersjournals.com/content/44/5/1103.extract Understanding the impact of physical activity in COPD outcomes: moving forward Richard ZuWallack and Cristóbal Esteban Eur Respir J 2014 44:1107-1109 http://erj.ersjournals.com/content/44/5/1107.extract A conceptual framework for reporting experience of physical activity in COPD Enrico M. Clini and Laura Fregonese Eur Respir J 2014 44:1110-1112 http://erj.ersjournals.com/content/44/5/1110.extract Double tracer gas single-breath washout: promising for clinics or just a toy for research? Philipp Latzin and Bruce Thompson Eur Respir J 2014 44:1113-1115 http://erj.ersjournals.com/content/44/5/1113.extract Do we need new asthma control tests? Jean Bousquet, Arnaud Bourdin, and Pascal Demoly Eur Respir J 2014 44:1116-1118 http://erj.ersjournals.com/content/44/5/1116.extract Should use of 4 hours continuous positive airway pressure per night be considered acceptable compliance? Juan F. Masa and Jaime Corral-Peñafiel Eur Respir J 2014 44:1119-1120 http://erj.ersjournals.com/content/44/5/1119.extract Microvascular disease in chronic thromboembolic pulmonary hypertension: the story continues William R. Auger and Nick H. Kim Eur Respir J 2014 44:1121-1122 http://erj.ersjournals.com/content/44/5/1121.extract Negative clinical trials in sarcoidosis: failed therapies or flawed study design? David R. Moller Eur Respir J 2014 44:1123-1126 http://erj.ersjournals.com/content/44/5/1123.extract

European Lung Corner

Implementing the European Respiratory Roadmap: halfway there? Nadia Kamel Eur Respir J 2014 44:1127-1129 http://erj.ersjournals.com/content/44/5/1127.extract

ERS Task Force Report

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine Alyn H. Morice, Eva Millqvist, Maria G. Belvisi, et al. Eur Respir J 2014 44:1132-1148 http://erj.ersjournals.com/content/44/5/1132.abstract

Original Articles

Cough

A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response Alyn H. Morice, Adam D. Jakes, Shoaib Faruqi, et al. and The Chronic Cough Registry Eur Respir J 2014 44:1149-1155 http://erj.ersjournals.com/content/44/5/1149.abstract

COPD

Characterisation and impact of reported and unreported exacerbations: results from ATTAIN Paul W. Jones, Rosa Lamarca, Ferran Chuecos, et al. Eur Respir J 2014 44:1156-1165 http://erj.ersjournals.com/content/44/5/1156.abstract Prospective validation of the endurance shuttle walking test in the context of bronchodilation in COPD Benoit Borel, Véronique Pepin, Donald A. Mahler et al. Eur Respir J 2014 44:1166-1176 http://erj.ersjournals.com/content/44/5/1166.abstract Mechanisms of exercise intolerance in Global Initiative for Chronic Obstructive Lung Disease grade 1 COPD Jordan A. Guenette, Roberto C. Chin, Sicheng Cheng, et al. Eur Respir J 2014 44:1177-1187 http://erj.ersjournals.com/content/44/5/1177.abstract Skeletal muscle adiposity is associated with physical activity, exercise capacity and fibre shift in COPD Matthew Maddocks, Dinesh Shrikrishna, Simone Vitoriano, et al. Eur Respir J 2014 44:1188-1198 OPEN ACCESS ARTICLE http://erj.ersjournals.com/content/44/5/1188.abstract Changes in physical activity and all-cause mortality in COPD Anouk W. Vaes, Judith Garcia-Aymerich, Jacob L. Marott, et al. Eur Respir J 2014 44:1199-1209 http://erj.ersjournals.com/content/44/5/1199.abstract Double tracer gas single-breath washout: reproducibility in healthy subjects and COPD Kim Husemann, Nina Berg, Jennifer Engel, et al. Eur Respir J 2014 44:1210-1222 http://erj.ersjournals.com/content/44/5/1210.abstract

Rehabilitation

The PROactive innovative conceptual framework on physical activity Fabienne Dobbels, Corina de Jong, Ellen Drost, et al., and the PROactive consortium Eur Respir J 2014 44:1223-1233 OPEN ACCESS ARTICLE http://erj.ersjournals.com/content/44/5/1223.abstract

Asthma

Human leukocyte antigen class II variants and adult-onset asthma: does occupational allergen exposure play a role? Lidwien A.M. Smit, David P. Strachan, Roel Vermeulen, et al. Eur Respir J 2014 44:1234-1242 http://erj.ersjournals.com/content/44/5/1234.abstract Development and validation of the RAND Asthma Control Measure Marielena Lara, Maria Orlando Edelen, Nicole K. Eberhart, Brian D. Stucky, and Cathy D. Sherbourne Eur Respir J 2014 44:1243-1252 http://erj.ersjournals.com/content/44/5/1243.abstract

Cystic fibrosis

Cyanide levels found in infected cystic fibrosis sputum inhibit airway ciliary function Chandrika Nair, Amelia Shoemark, Mario Chan, et al. Eur Respir J 2014 44:1253-1261 http://erj.ersjournals.com/content/44/5/1253.abstract

Sleep

Intensive versus standard follow-up to improve continuous positive airway pressure compliance Izolde Bouloukaki, Katerina Giannadaki, Charalampos Mermigkis, et al. Eur Respir J 2014 44:1262-1274http://erj.ersjournals.com/content/44/5/1262.abstract

Pulmonary vascular diseases

Microvascular disease in chronic thromboembolic pulmonary hypertension: a role for pulmonary veins and systemic vasculature Peter Dorfmüller, Sven Günther, Maria-Rosa Ghigna, et al. Eur Respir J 2014 44:1275-1288 http://erj.ersjournals.com/content/44/5/1275.abstract

Pulmonary infections

Mycobacterial diseases developed during anti-tumour necrosis factor-α therapy Jung-Wan Yoo, Kyung-Wook Jo, Bo-Hyung Kang, et al. Eur Respir J 2014 44:1289-1295 http://erj.ersjournals.com/content/44/5/1289.abstract

Sarcoidosis

Safety and efficacy of ustekinumab or golimumab in patients with chronic sarcoidosis Marc A. Judson, Robert P. Baughman, Ulrich Costabel, et al. Eur Respir J 2014 44:1296-1307 http://erj.ersjournals.com/content/44/5/1296.abstract

Review

Inhaled antibiotics: dry or wet? Harm A.W.M. Tiddens, Aukje C. Bos, Johan W. Mouton, Sunalene Devadason, and Hettie M. Janssens Eur Respir J 2014 44:1308-1318 http://erj.ersjournals.com/content/44/5/1308.abstract

Back to Basics

Interleukin-17 cytokine signalling in patients with asthma Anders Lindén and Barbro Dahlén Eur Respir J 2014 44:1319-1331http://erj.ersjournals.com/content/44/5/1319.abstract

State of the Art

Number 3 in the series “Multimorbidity and the lung”: Ageing and the border between health and disease William MacNee, Roberto A. Rabinovich, and Gourab Choudhury Eur Respir J 2014 44:1332-1352 http://erj.ersjournals.com/content/44/5/1332.abstract

Agora

Research letters

Small airway dysfunction is associated with poorer asthma control Arvind Manoharan, William J. Anderson, Joseph Lipworth, Ibrahim Ibrahim, and Brian J. Lipworth Eur Respir J 2014 44:1353-1355 http://erj.ersjournals.com/content/44/5/1353.extract Reduced lung function and the risk of out-of-hospital sudden cardiac death Sudhir Kurl, Sae Young Jae, and Jari A. Laukkanen Eur Respir J 2014 44:1355-1357 http://erj.ersjournals.com/content/44/5/1355.extract Autonomic dysregulation: a mechanism of asthma death Jaymin B. Morjaria, Tim Rowland, Puneet Tailor, Shaan Hyder, Caroline E. Wright, Simon P. Hart, and Alyn H. Morice Eur Respir J 2014 44:1357-1360 http://erj.ersjournals.com/content/44/5/1357.extract Low socioeconomic status is associated with worse lung function in the Danish cystic fibrosis population David C. Taylor-Robinson, Karsten Thielen, Tania Pressler, et al. Eur Respir J 2014 44:1363-1366 OPEN ACCESS ARTICLE http://erj.ersjournals.com/content/44/5/1363.extract The impact of novel tests for tuberculosis depends on the diagnostic cascade Amanda Y. Sun, Claudia M. Denkinger, and David W. Dowdy Eur Respir J 2014 44:1366-1369 http://erj.ersjournals.com/content/44/5/1366.extract An evaluation of the use of a negative interferon-γ release assay for tuberculosis screening before TNF antagonist therapy Georgia Woodfield, Benjamin Passey-Heaton, Anob Chakrabarti, et al. Eur Respir J 2014 44:1369-1372 http://erj.ersjournals.com/content/44/5/1369.extract Prevalence, screening and treatment of latent tuberculosis among oral corticosteroid recipients Nicholas T. Vozoris, Julie Seemangal, and Jane Batt Eur Respir J 2014 44:1373-1375 http://erj.ersjournals.com/content/44/5/1373.extract

CHEST: November 2014; Volume 146, Number 5

Editorials

Hepatocyte Growth Factor Deficiency in COPD: A Mechanism of Emphysema and Small Airway Fibrosis? Peter J. Barnes Chest. 2014;146(5):1135-1136. Primary Ciliary Dyskinesia and the Heart: Cilia Breaking Symmetry Marcus P. Kennedy; Barry J. Plant Chest. 2014;146(5):1136-1138. Fibroproliferative ARDS in the Era of Low-Tidal-Volume Ventilation Manu Jain Chest. 2014;146(5):1140-1142.

Original Research: COPD

Simultaneous Assessment of Hepatocyte Growth Factor and Vascular Endothelial Growth Factor in Epithelial Lining Fluid From Patients With COPD Hiroshi Kanazawa; Yoshihiro Tochino; Kazuhisa Asai; Kazuto Hirata Chest. 2014;146(5):1159-1165. Five-Year Cohort Study: Emphysematous Progression of Indium-Exposed Workers Makiko Nakano; Kazuyuki Omae; Kazuhiko Uchida; et al. Chest. 2014;146(5):1166-1175. doi:10.1378/chest.13-2484

Original Research: Critical Care

Detection of Fibroproliferation by Chest High-Resolution CT Scan in Resolving ARDS Ellen L. Burnham; Robert C. Hyzy; Robert Paine, III; et al. Chest. 2014;146(5):1196-1204. Long-term Outcomes After In-Hospital CPR in Older Adults With Chronic Illness Renee D. Stapleton; William J. Ehlenbach; Richard A. Deyo; J. Randall Curtis Chest. 2014;146(5):1214-1225.

Original Research: Sleep Disorders

Effect of Oxygen and Acetazolamide on Nocturnal Cardiac Conduction, Repolarization, and Arrhythmias in Precapillary Pulmonary Hypertension and Sleep-Disturbed Breathing Deborah S. Schumacher; Séverine Müller-Mottet; Elisabeth D. Hasler; et al. Chest. 2014;146(5):1226-1236.

Original Research: Asthma

Controlling Asthma by Training of Capnometry-Assisted Hypoventilation (CATCH) vs Slow Breathing: A Randomized Controlled Trial Thomas Ritz; David Rosenfield; Ashton M. Steele; Mark W. Millard; Alicia E. Meuret Chest. 2014;146(5):1237-1247.

Original Research: Diffuse Lung Disease

Distinct Characteristics of Pleuroparenchymal Fibroelastosis With Usual Interstitial Pneumonia Compared With Idiopathic Pulmonary Fibrosis Tsuneyuki Oda; Takashi Ogura; Hideya Kitamura; et al. Chest. 2014;146(5):1248-1255. Study Design Implications of Death and Hospitalization as End Points in Idiopathic Pulmonary Fibrosis Harold R. Collard; Kevin K. Brown; Fernando J. Martinez; et al.; for the IPFnet Investigators Chest. 2014;146(5):1256-1262.

Original Research: Pulmonary Vascular Disease

Characterization of First-Time Hospitalizations in Patients With Newly Diagnosed Pulmonary Arterial Hypertension in the REVEAL Registry Charles D. Burger; Pamela K. Long; Monarch R. Shah; et al. Chest. 2014;146(5):1263-1273. Acute Hemodynamic Effects of Riociguat in Patients With Pulmonary Hypertension Associated With Diastolic Heart Failure (DILATE-1): A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study Diana Bonderman; Ingrid Pretsch; Regina Steringer-Mascherbauer; et al. Chest. 2014;146(5):1274-1285.

Original Research: Pulmonary Procedures

Novel Use of Pleural Ultrasound Can Identify Malignant Entrapped Lung Prior to Effusion Drainage Matthew R. Salamonsen; Ada K. C. Lo; Arnold C. T. Ng; et al. Chest. 2014;146(5):1286-1293.

Original Research: Signs and Symptoms of Chest Diseases

Decreased Cough Sensitivity and Aspiration in Parkinson Disease Michelle S. Troche; Alexandra E. Brandimore; Michael S. Okun; Paul W. Davenport; Karen W. Hegland Chest. 2014;146(5):1294-1299.

Original Research: Cardiothoracic Surgery

Thoracoscopic Pneumonectomy: An 11-Year Experience Athar Battoo; Ariba Jahan; Zhengyu Yang; et al. Chest. 2014;146(5):1300-1309.

Original Research: Chest Infections

Rapid Detection of Mycobacterium tuberculosis Using a Novel Ultrafast Chip-Type Real-Time Polymerase Chain Reaction System Seung Hyeun Lee; Sung-Woo Kim; Sehyun Lee; et al. Chest. 2014;146(5):1319-1326.

Original Research: Occupational and Environmental Lung Diseases

Prevalence, Clinical Profile, Iron Status, and Subject-Specific Traits for Excessive Erythrocytosis in Andean Adults Living Permanently at 3,825 Meters Above Sea Level Aldo De Ferrari; J. Jaime Miranda; Robert H. Gilman; et al. CRONICAS Cohort Study Group Chest. 2014;146(5):1327-1336.

Translating Basic Research Into Clinical Practice

Scientific Foundations of Allergen-Specific Immunotherapy for Allergic Disease Michael B. Soyka; Willem van de Veen; David Holzmann; Mübeccel Akdis; Cezmi A. Akdis Chest. 2014;146(5):1347-1357.

Recent Advances in Chest Medicine

Diagnosis and Treatment of Pulmonary Aspergillosis Syndromes Karen C. Patterson; Mary E. Strek Chest. 2014;146(5):1358-1368. doi:10.1378/chest.14-0917

Evidence-Based Medicine

Methodologies for the Development of the Management of Cough: CHEST Guideline and Expert Panel Report Sandra Zelman Lewis; Rebecca L. Diekemper; Cynthia T. French; et al.; on behalf of the CHEST Expert Cough Panel Chest. 2014;146(5):1395-1402.

Selected Reports

Refractory Hypoxemia in a 23-Year-Old Patient With Budd-Chiari Syndrome Jeroen J. H. Bunge; Ubbo S. Wiersema; Adriaan Moelker; Jasper van Bommel; Eric T. T. L. Tjwa Chest. 2014;146(5):e149-e152. Bilateral Vocal Cord Paralysis Requiring Tracheostomy Due to Neuroborreliosis Carlos D. Martínez-Balzano; Bruce Greenberg Chest. 2014;146(5):e153-e155.

Ultrasound Corner

An Elderly Woman That Presents With Absent Vital Signs Robert T. Arntfield; Scott J. Millington; Edwin Wu Chest. 2014;146(5):e156-e159.

Pulmonary, Critical Care, and Sleep Pearls

A 70-Year-Old Man With Intraoperative Hypoxia and Hypotension During Total Hip Replacement Mariam A. Alansari; Ahmed A. Abdulmomen Chest. 2014;146(5):e160-e162. A 54-Year-Old Woman With Postextubation Stridor Eugene Shostak; Adnan Majid; Colleen Channick Chest. 2014;146(5):e163-e166.

Articles from Other Journals The effects of a physiotherapy programme on patients with a pleural effusion: a randomized controlled trial G Valenza-Demet, MC Valenza, I Cabrera-Martos, I Torres-Sánchez, and F Revelles-Moyano Clin Rehabil November 2014 28: 1087-1095 Abstract The effects of elastic tubing-based resistance training compared with conventional resistance training in patients with moderate chronic obstructive pulmonary disease: a randomized clinical trial

Ercy Mara Cipulo Ramos, Alessandra Choqueta de Toledo-Arruda, Luciana Cristina Fosco, et al. Clin Rehabil November 2014 28: 1096-1106 Abstract

Simvastatin in the Acute Respiratory Distress Syndrome Daniel F. McAuley, M.D., John G. Laffey, M.D., Cecilia M. O'Kane, Ph.D., et al. and the HARP-2 Investigators, for the Irish Critical Care Trials Group N Engl J Med 2014; 371:1695-1703 October 30, 2014 http://www.nejm.org/doi/full/10.1056/NEJMoa1403285?query=TOC

Effectiveness of integrated disease management for primary care chronic obstructive pulmonary disease patients: results of cluster randomised trial. Kruis AL, Boland MR, Assendelft WJ, et al. BMJ. 2014 Sep 10;349:g5392. doi: 10.1136/bmj.g5392. Free PMC Article

Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease [Review Article] Lydia Finney MD, Matthew Berry MD, Aran Singanayagam MD, et al. The Lancet Respiratory Medicine, Volume 2, Issue 11, Pages 919 - 932, November 2014 http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(14)70169-9/fulltext

Tumour cell proliferation (Ki-67) in non-small cell lung cancer: a critical reappraisal of its prognostic role. Warth A, Cortis J, Soltermann A, et al. Br J Cancer. 2014 Sep 9;111(6):1222-9.

Predictive value of the international association for the study of lung cancer/American Thoracic Society/European Respiratory Society classification of lung adenocarcinoma in tumor recurrence and patient survival. Hung JJ, Yeh YC, Jeng WJ, Wu KJ, Huang BS, Wu YC, Chou TY, Hsu WH. J Clin Oncol. 2014 Aug 1;32(22):2357-64.

High-dose rifapentine with moxifloxacin for pulmonary tuberculosis. Jindani A, Harrison TS, Nunn AJ, et al.; RIFAQUIN Trial Team. N Engl J Med. 2014 Oct 23;371(17):1599-608. Free Article

A four-month gatifloxacin-containing regimen for treating tuberculosis. Merle CS, Fielding K, Sow OB, et al.; OFLOTUB/Gatifloxacin for Tuberculosis Project. N Engl J Med. 2014 Oct 23;371(17):1588-98. Free Article Sleep disorders in pregnancy. Oyiengo D, Louis M, Hott B, Bourjeily G. Clin Chest Med. 2014 Sep;35(3):571-87. Review.

Sleep and breathing in congestive heart failure. Rosen D, Roux FJ, Shah N. Clin Chest Med. 2014 Sep;35(3):521-34. Review.

Sleep in patients with restrictive lung disease. Won CH, Kryger M. Clin Chest Med. 2014 Sep;35(3):505-12. Review.

Cystic fibrosis and sleep. Katz ES. Clin Chest Med. 2014 Sep;35(3):495-504. Review.

Sleep in asthma. Khan WH, Mohsenin V, D'Ambrosio CM. Clin Chest Med. 2014 Sep;35(3):483-93. Review.

Sleep and respiratory physiology in adults. Sowho M, Amatoury J, Kirkness JP, Patil SP. Clin Chest Med. 2014 Sep;35(3):469-81. Review.

Sleep and breathing. Newton K, Malik V, Lee-Chiong T. Clin Chest Med. 2014 Sep;35(3):451-6. Review.

Pneumococcal vaccine and patients with pulmonary diseases. Mirsaeidi M, Ebrahimi G, Allen MB, Aliberti S. Am J Med. 2014 Sep;127(9):886.e1-8. Review.

Assessing standardization of molecular testing for non-small-cell lung cancer: results of a worldwide external quality assessment (EQA) scheme for EGFR mutation testing. Patton S, Normanno N, Blackhall F, Murray S, Kerr KM, Dietel M, Filipits M, Benlloch S, Popat S, Stahel R, Thunnissen E. Br J Cancer. 2014 Jul 15;111(2):413-20. Getting Control of Uncontrolled Asthma Michael E. Wechsler American Journal of Medicine, November 2014, 127(11), p1049–1059

Improving Adherence for Management of Acute Exacerbation of Chronic Obstructive Pulmonary Disease Lindsay Sonstein, Carlos Clark, Susan Seidensticker, Li Zeng, Gulshan Sharma American Journal of Medicine, November 2014, 127(11), p1097–1104

Percutaneous strategies for the management of pulmonary parenchymal, chest wall, and pleural metastases. Al-Tariq QZ. AJR Am J Roentgenol. 2014 Oct;203(4):709-16. Review.

Can early introduction of specialized palliative care limit intensive care, emergency and hospital admissions in patients with severe and very severe COPD? a randomized study Weber C, Stirnemann J, Herrmann FR, Pautex S, Janssens J BMC Palliative Care 2014, 13:47 (21 October 2014) http://www.biomedcentral.com/1472-684X/13/47/abstract

Evidence Updates Garin N, Genne D, Carballo S, et al. beta-Lactam Monotherapy vs beta-Lactam-Macrolide Combination Treatment in Moderately Severe Community-Acquired Pneumonia: A Randomized Noninferiority Trial. JAMA Intern Med. 2014 Oct 6. doi: 10.1001/jamainternmed.2014.4887. (Original) http://plus.mcmaster.ca/EvidenceUpdates/NewArticles.aspx?Page=1&ArticleID=60807#Data

From NICE Medicines Awareness Weekly: Chronic obstructive pulmonary disease: umeclidinium/vilanterol combination inhaler (Anoro Ellipta) - evidence summary new medicine (ESNM49) National Institute for Health and Care Excellence Respiratory disorders

RCTs comparing umeclidinium/vilanterol combination inhaler with its individual components, tiotropium monotherapy and placebo, suggest it has benefits for FEV1. However, clinical relevance of these benefits is unclear and there is limited evidence on patient-orientated outcomes. Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis. Langton Hewer SC, Smyth AR. Cochrane Database Syst Rev. 2014 Nov 10;11:CD004197.

Colobreathe (colistimethate sodium dry powder for inhalation): risk of capsule breakage—new instructions for use Medicines and Healthcare products Regulatory Agency Respiratory disorders The MHRA has received 26 Yellow Card reports of Colobreathe (colistimethate sodium) capsules shattering when pierced by their inhaler device. The manufacturer has revised the instructions for inhaler use and this should be demonstrated to patients, and the first dose supervised.

Royal College of Physicians Report COPD: Who cares? National COPD Audit Programme: Resources and organisation of care in acute NHS units in England and Wales 2014 Royal College of Physicians Respiratory disorders This report presents results from the National COPD Secondary Care Audit of resources and organisation of care (results of the clinical audit are due to be published in Feb 2015). The report finds that patient care has improved but some services continue to vary widely.

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