CTSA Inventory Resource Web Presence (CIRWP)A web-accessible and searchable inventory of research resources of the CTSA consortium

Tim T. Morris4, Charles D. Borromeo

1, Beth Kirschner

2, Harpreet Singh MS

1, Jessica D. Tenenbaum PhD

3, Nancy B. Whelan

1, Davera Gabriel RN

5,

Kent Anderson MS5, Trish Whetzel PhD

6, Csongor I. Nyulas MS

6, Barbara R. Mirel DArts

2, Paul Saxman MS

2, Zachery Wright MSI

2, Peter Boisvert

2,

Daniel L. Rubin, MD MS6, Brian D. Athey PhD

2, Michael J. Becich MD PhD

1, Kevin A. Smith MSIS

2

1University of Pittsburgh,

2University of Michigan,

3Duke University,

4Emory University,

5University of California Davis,

6Stanford University

AbstractCIRWP is a web-accessible and searchable inventory of

research resources of the CTSA consortium. A proof of

concept prototype, the architecture extends the NCBC

Biositemaps1 infrastructure, enabling institutions to follow

guidelines for producing their own standards-compliant

inventories or use CIRWP tools for authoring and search.

Future uses by other groups will lead to even more effective

and efficient resource discovery and sharing across CTSA,

NCBC and other extramural and intramural NIH programs.

Specific Aims1) Create an inventory of tools and technologies adopted by

CTSA funded institutions.

2) Catalog and publish the resource inventory collected by

the CTSA Informatics IRWG.

3) Build and deploy a well-documented, standards-based

informatics infrastructure to enable a federated, web-

accessible catalog of resources that enable clinical and

translational research.

Notable Accomplishments1) Standards-based Informatics Infrastructure -

· CTSA Inventory Information Model (harmonized with NCBC)

· Biomedical Resource Ontology2 (BRO) Extensions for annotating

descriptions of CTSA resources

· development of a CTSA Inventory Editor3 based on the NCBC counterpart

· development and deployment of web services in support of a distributed

web-accessible inventory framework (hosted on NCBC server resources)

· integration of the CTSA framework with NCBC Biositemaps registry for

registration of distributed RDF inventory files; and development and

· development and deployment of a CTSA query tool5 incorporating faceted

classification and usability best practices

2) Full or partial inventories of informatics resources (370)

across thirty-seven (37) CTSA sites with five sites

completing inventories of translational sciences resources.

3) Published and web-accessible resources for informatics

and translation sciences in compliance with CIRWP

guidelines with a front-end interface that enables users to

query, browse results by categories such as institution or

types of resources, easily refine or expand queries, and

save or send items of interest to others.

http://biositemaps.org/cirwp

Leveraging NIH Initiatives . . .The CTSA Inventory Resource Web Presence (CIRWP)

project leverages and builds upon several existing NIH

funded initiatives –

1) CTSA Informatics Inventory and Resources Workgroup

(IRWG)

2) National Centers for Biomedical Computing (NCBC)

Working Groups

3) CTSA Administrative Supplement “CTSA National

Resource Database for Translational (T1) Research”

User-Oriented Recommendations

To address the needs of the heterogeneous users of CIRWP V3, we identified numerous criteria for success. In

creating designs to meet these criteria, we sought to maintain and apply strengths from prior prototypes and

comparable sites. We also sought to overcome weaknesses that our evaluations and reviews revealed. Some

aspects of our designs and requirements depend on additional work in web services, RDF structures, the

information model, and Editor.

Proposed Design and User Requirements Highlights

· Multi-mode search: Facets, Free text, Advanced, Hybrid (free text + the other 2)

· Ease of navigating BRO categories for facets and advanced searches

· Simple means (to users) for refining a search or choosing to start a new search

· Retrieved items from free text queries reflecting a search of all fields; query terms highlighted in the results display

· Results in tables with sortable columns, including clickable values for access to resources, contact names, the resource record

· Mechanisms for saving/export

· Front and back-end mechanisms for social aspects - to be built out over time

· Geographical location-based resource mapping

· Mechanisms for keeping users oriented and confidence (e.g. breadcrumbs, counts, Help/FAQs, persistence of last-entered free text query terms)

Future Goals1) Accelerated development and harmonization of

Biositemaps across NCBCs, CTSAs and other applicable

NIH-funded organizations.

2) Promotion and outreach of this information framework,

using web and print-based media, web-based seminars and

presentations, and participation in national meetings.

The Clinical and Translational Science Awards (CTSA) is a registered trademark of DHHS

User-Oriented EvaluationsWe evaluated and created user-centered designs for CIRWP V3. These

designs will help users search, browse, and access CTSA / NCBC

resources efficiently and effectively.

Heuristic evaluations of early prototypes -

Biositemaps and the Pittsburgh Informatics

Tool Inventory and mockups of CIRWP V3

Comparative heuristic evaluation of the

Neuroscience Information Framework (NIF),

which has been developed and revised

based on usability evaluations.

Critical reviews of comparative search /

explore sites and relevant literature

Design sessions structured by use cases with

iterative prototyping with HTML mock-ups

Cross-team discussions of priorities for

design and development

Interviews with translational investigators

regarding resource requirements in the context

of their specific research

The CTSA Information Model defines properties of

biomedical resources and include such attributes as resource name,

organization, center or institute, research program, description, resource

type, related areas of research, related activities, url, keywords, technical

support, documentation available, resource sharable, contact person,

contact person email, contact person, phone . . .

Acknowledgements

University of Pittsburgh

Michael J. Becich MD PhD

Charles D. Borromeo

Harpreet Singh MS

Nancy B. Whelan

University of Michigan

Brian D. Athey PhD

Aaron Bookvich

Peter Boisvert

Beth Kirschner

Barbara R. Mirel DArts

Paul Saxman MS

Kevin A. Smith MSIS

Zachary Wright MSI

Stanford University

Csongor I. Nyulas MS

Daniel L. Rubin MD MS

Trish Whetzel PhD

Oregon Health & Science University

Shannon McWeeney PhD

University of Texas Houston

Elmer V. Bernstam MD MSE MS

Duke University

Jessica D. Tenenbaum PhD

Emory University

Tim T. Morris

University of California Davis

Kent Anderson MS

Davera Gabriel RN

Alice Tarantal PhD

University of California San Diego

Maryann E. Martone, PhD

National Institutes of Health

Elaine Collier MD

Peter Lyster PhD

Project Members

Inventory Resources Working Group

Members (38 POCs)

Bill Adams, Rebecca Bamber,

Edward Barbour, Teresa Bosler, Jim

Brinkley, Christopher Chute, Curtis

Cole, Will Digrazio, David Eichmann,

Joe Ellefson, Larry Errecary, Sandy

Frawley, Steve Johnson, Josef

Kalna, Michael Kamerick, Warren

Kibbe, Matthew Kristin, Bernie

LaSalle, Elliot Lefkowitz, Harold

Lehmann, Sandy Mackenzie, Doug

McFadden, Rekha Meyer, Marc

Overhage, Philip Payne, David

Pilasky, Brad Pollock, Mark Porter,

Dan Schwartz, Jonathan Silverstein,

Rob Taylor, Tom Yeager

CTSA

Administrative Supplements

Pittsburgh, 3UL1RR024153-03S1

Duke, 5UL1RR024128-03S1

Cost Share

Emory University CTSA, 1UL1RR025008-01

University of California Davis CTSA, 1UL1RR024146-01

University of Michigan CTSA, 1UL1RR024986-01

University of Pittsburgh CTSA, 1UL1RR024153-01

NCBC

National Center for Integrative Biomedical Informatics,

3U54DA021519-04S1

National Center for Biomedical Ontology, 3U54HG004028-04S1

Funding Provided by

Getting Involved

Inventory CurationCuration text goes here . . . Someone to work with

institutional leadership to identify and annotate resources to

publish . . . Includes “tagging” resources with BRO terms . .

.

Creating RDF file . . .Using the CTSA Biositemaps Editor to create rdf file . . .

Publishing and Registering RDF file . . .To website that at your institution that is . . . .

Promoting CIRWP at your institution . . .Help us promote CIRWP . . .

Working with the CIRWP team to make it better . . .Help us promote CIRWP . . .

Reach us at . . .

cirwp@biositemaps.org