csf b – lymphocyte chemoattractant (cxcl13) in the early diagnosis of acute lyme neuroborreliosis
TRANSCRIPT
J Neurol (2008) 255:782DOI 10.1007/s00415-008-0974-8 ERRATUM
JON
297
4
When we published the article
“Ljøstad U, Mygland Å (2008) CSF B – lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis. J Neurol (published online March 17th 2008) [The original article can be found at http://dx.doi.org/10.1007/s00415-008-0785-y]”
sadly, the author’s corrections had been done only partially.
The last sentence of the second paragraph of the Abstract should read:
“Pre-treatment sensitivity of elevated CSF Bb Al was 100 % (95 % CI = 91–100) and 89 % (95 % CI = 75–96) respectively (p = 0.053).”
In the table below Fig. 2 and in Table 3 two values had not been corrected. The correct files are published below.
And the first sentence in the second paragraph of the Discussion should read:
“The diagnostic sensitivity of an elevated CSF CXCL13 was 100 % as com-pared to 89 % of a positive BbAl (p = 0.053).”
The publisher apologises for any inconvenience caused by this mistake.
Definite
LNB
n = 37
Probable
LNB
n = 7
Possible
LNB
n = 7
Not
LNB
n = 8
MS
n = 31
NIND
n = 11
Non-lyme
meningitis
n = 10
p value
Mean CSF CXCL13
(ng/g total CSF protein)
(95% confidence interval)
3524
(1813-5235)
1319
(-1203-3840)
356
(-418-1131)
9
(-3-21)
27
(8-46)
0 23
(-2-48)
< 0.001
Mean CSF cell count
(95% confidence interval)
256
(169-343)
49
(14-84)
107
(24-191)
37
(-33-107)
11
(4-19)
2
(1-3)
852
(-223-1927)
< 0.001
° Outliers * Extreme values.
Table 3 Calculated test accuracies
Definite LNB Not LNB (n = 37) (n = 8)
CSF CXCL13 elevated 37 3 Pos Bb AI 33 3
CSF CXCL13 not detectable 0 5 Neg Bb AI 4 5
Sensitivity: Specificity: CSF CXCL13 100 % CSF CXCL13 63 % (95 % CI = 91–100) (95 % CI = 31–86) Bb AI 89 % Bb AI 63 % (95 % CI = 75–96) (95 % CI = 31–86) P = 0.053 P = 1.00
Fig. 2 Distribution of CSF CXCL13 con-centrations. CSF CXCL13 concentrations >1500 ng/g total CSF protein are not further specified in the figure, but mean CSF CXCL13 for each diagnostic group is indicated in the table
782_782_Erratum_JON_2974.indd 782782_782_Erratum_JON_2974.indd 782 14.05.2008 14:13:53 Uhr14.05.2008 14:13:53 Uhr