Phytessence Purple GinsengA True Beauty Coach

TCM EnergyProtectionAdaptogen

Combat skin imbalancesSebum protects the skin and hair against external stress factors and dehydration. Composed mainly of waxes, triglycerides and fatty acids, sebum contains an exclusive ingredient, squalene, a powerful antioxidant that is degraded into squalene peroxide by UV rays. Squalene peroxide is implicated in the release of inflammatory mediators, the proliferation and enlargement of sebaceous glands, the overproduction of sebum and the appearance of comedo and acne blemishes.

The effects of Phytessence Purple Ginseng are evaluated in vitro by measuring the level of leukotrienes B4 synthesized by lipoxygenase (LOX) after induction with squalene peroxide (Sq-P). LOX, a lipidic peroxidation catalyst, is an enzyme involved in inflammatory reactions and the production of sebum.

PropertiesSeboregulator

AstringentAntibacterial

ApplicationsBB creamComplexion enhancerAnti-shine lotion

Member of Croda International Plc

-21%

Untreated cells+ Sq-P induction

Cells treated with Phytessence Purple Ginseng (%)+ Sq-P induction

0 0.002 0.004 0.01 0.02

1.00

0.90

0.80

0.70

LTB

4 re

leas

e (p

g/g

pro

tein

)

Phytessence Purple Ginseng inhibits lipoxygenase activity dose-dependently.The release of the inflammatory mediator LTB4 is reduced by 21% in the presence of only 0.02% Phytessence Purple Ginseng.

Release of the inflammatory mediator LTB4 by human keratinocytes

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harlo

tte B

rett

Pho

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aphy

Healthy-looking skin and hairA perfect complexion, healthy scalp and naturally beautiful hair: every consumer dreams of this sort of faultless appearance. Cleansing, purifying, balancing and mattifying are the key-words of anti-blemish treatment claims. In the international facial and hair care markets, consumers rank this demand in third position after moisturising and plant origin.

Among imperfections, one of the main skin imbalances is hyperseborrhoea. Combatting it reduces the appearance of comedones, infections and redness and minimises shine of skin and hair.

Sebum is a reflection of skin imbalances

Traditional informationKnown the world over, Purple ginseng or Dragonwort is a perennial aquatic plant qualified as ginseng for its adaptogenic properties. Used in herbal medicine, its rhizome is described as an energizing astringent and a powerful tonic recognized for the treatment of inflammation of the mucous membranes and venous insufficiency.

While the primitive tribes in the Caucasus region used it to purify the blood, in the history of TCM, the illustrated Pharmacopoeia (Compendium of Materia Medica) recommends it to reduce oedema and flushing, and to detoxify the body.

Purple ginseng combats skin and scalp imperfections thanks to its catechic and gallic tannins and chlorogenic acid ingredients. Its powerful agents provide it with antioxidant, anti-inflammatory and antibacterial properties.

NA22474 Technical informationINCI name: Glycerin, Water, Alcohol, Polygonum Bistorta Root ExtractPart used: RootsSynonyms: Dragonwort, Bistort, Zi shen (), Quan shen ()Chinese regulation: Ingredients listed in CTFA 2004/SFDA2007 and IECIC 2003Recommended percentage: 1 - 5%

Manufacturing process: Multistep extraction

Active molecules Related activitiesCatechic and gallic tannins Antioxidant, astringent, inhibitor of lipid peroxidation Quantification by Folin method

Chlorogenic acid Radical scavenging, energizing, antibacterial

ZA Les Plaines, 48230 Chanac, France Tel (+33) 4 66 48 20 27, Fax (+33) 4 66 48 28 41, marketing@crodarom.fr, www.crodarom.com

One of the most astringent medicinal plants

Revive your survival instinct! In todays world, our survival instinct must take over in order for us to cope with a universe full of unknowns. To combat the harmful effects of a hostile environment, our organism needs to adapt to the different forms of stress affecting it and to preserve its vital energy.

In Traditional Chinese Medicine (TCM), the notion of adaptogen has existed for thousands of years in the concept of superior tonics, which stimulate natural defences and increase energy.

As a true beauty coach, adaptogenic plants increase the skins resistance and vitality to help it cope with the demands of modern life and avoid the damage it may cause.

Ginseng, the reference adaptogenic plant