cranial nerves lesions

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    CRANIAL NERVESLESIONS

    Nur Adilah Mohd Radzi

    SN: 24MN: 27

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    Objectives

    • Functions of all the cranial nerves

    • Coon e!ects of lesions of thecranial nerves

    • Clinical e"aination

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    #ntroduction

    • 12 pairs of cranialnerves

    • Contains onl$ sensor$%bres Sensorycranial nerves: #& ## and'###

    • (redoinantl$ otor infunction Motorcranial nerve: ###& #'&'#& )# and )##

    • *oth sensor$ +otor %bres Mixedcranial nerve: '&

    '##& #) and )

    • Lesion: A re,ion inan or,an- tissue

    .hich has su!ereddaa,e throu,hinjur$ or disease

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    CN #: Olfactor$ Nerve

    • Sensor$ cranial nerve

    • Function: Smell

    • Resides on the roof of

    the nasal cavit$ Fro the olfactor$ucosa forainaon the cribrifor0late  olfactor$bulb  olfactor$ tract

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    CN #: Olfactor$ nerve

    • 1esion Anosia&$0osia& (arosia&Olfactor$ hallucination

    • Anosmia &yposmia  – 3nilaterall$ uour

    of olfactor$ bulb orfrontal lobe&

    Menin,ioa – *ilaterall$  Coon

    cold& ead injur$&Atro0hic rhinitis

    • !arosmia 5distortion of sellsensation6

    • Ol"actory#all$cination

    Causes:

    Mental disorders

    80ile0s$

    ead injur$

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    CN #: Clinical 8"aination

    • Sell is tested ineach nostril se0aratel$ b$ 0lacin, stiuli

    under one nostriland occludin, theo00osin, nostril

     

    • 8,: oran,e-leon0eel& co!ee& orvine,ar

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    CN ##: O0tic Nerve•

    Function: 'ision

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    CN ##: O0tic Nerve

    • 1esion  visual %eld defects + loss ofvisual acuit$

    • Causes of lesion: – Fractures in the orbit

     – *rain lesions

     – %amae alon t#e vis$al pat#'ay

     – 9iseases of the nervous s$ste – (ituitar$ ,land tuor

     – Cerebral aneur$s

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    CN ##: %amae alon t#e vis$alpat#'ay 

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    CN ##: Clinical 8"aination

    •  est for: Acuit$& Colour& Fields&Ree"es

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    CN ##: Clinical 8"aination

    • Vis$al (elds aretested b$ as;in,the 0atient to loo;

    directl$ at $ou.hilst $ou .i,,leone of $our %n,ersin each of the four

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    CN ###' + '#: Oculootor& rochlear

    + Abducens

    • Function: Control the uscles thatove the e$eballs

    • 1esion: Strabisus& 0tosis& di0lo0ia

    • Causes of daa,e: – raua to the s;ull or brain

     – Co0ression

     – 1esions of the su0erior orbital %ssure

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    CN ###' + '#: Clinical8"aination

    •  he %n,er isoved in an **s#ape and the

    0atient is as;ed tore0ortan$ diplopia

    • (u0illar$ ree"

    •  he accoodationree" is tested b$ovin, the tar,etto.ards the

    0atient>s nose

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    CN ###: Oculootor Nerve

    • A otor nerve

    • Functions:

    Control

    oveents ofe$eball

    Controls the sizeof 0u0il

    #nvolved inaccoodation ofvision

    •  he lesion in thisnerve a$ result

    in:i= (tosis

    ii= N$sta,us

    iii= Strabisus

    iv= 9i0lo0ia

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    CN ###: Oculootor Nerve

    i= (tosis

    Causes:

    • #0airent of CN### functions

    • M$asthenia ,ravis

    ii= N$sta,us

    ?er;$ oveent ofthe e$eball

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    CN ###: Oculootor Nerve

    iv= 9i0lo0ia

    Causes:

    Can also ha00en in

    CN ###& CN #' + CN'#

    iii= Strabisus

    - S

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    CN #': rochlear Nerve

    • A otor cranial nerve

    • Su00l$ s$perior o+li,$e m$scle ofe$es

    • Function: 9e0ress e$es .hen inadduction

    • 1esion @ 9i0lo0ia 5double vision6

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    CN ': ri,einal Nerve

    • Mi"ed cranial nerve& lar,est

    • branches:

    i= 'B: O0thalic Nerve 8$e

    ii= ': Ma"illar$ Nerve  

    300er ja.boneiii= 'D: Mandibular Nerve 

    1o.er ja.bone

    •. Functions:

      Carr$in, ,eneral sensation

    fro di!erent 0art of theface& head + nec;

      Mastication

    • Lesion .ill cause:

     – Sensory de%cit

     – Motor de%cit

     – Re)ex de%cit

    Characterized b$:

    1oss sensation of touch&te0erature and

    0ro0rioce0tion- !aralysis of the uscle

    of mastication

    - 1oss of corneal ree"

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    CN ': ri,einal Nerve

    1esion of E or ore branches:

     -rieminal ne$ralia.tic do$lo$re$x/

    Shar0 cuttin,-tearin, 0ain&lasts for fe. seconds toinutes

    Coon in 0eo0le GH $earsold

    Causes: 1oo0in, blood vessel&defective $elin sheath

    Can be the %rst si,n of adisease: 9iabetes& ulti0lesclerosis& lac; vitain *B

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    CN ': Clinical 8"aination

    E= 1i,ht touch& 0ain+ te0erature

    2= Corneal ree"

    = Muscle ofastication5asseter +te0oralisuscles6

    4= ?a. jer;

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    CN '#: Abducens Nerve

    • A otor nerve

    • #nnervates lateralrectus uscle

    • 1esion a$ causedi0lo0ia and s

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    CN '##: Facial Nerve

    • Mi"ed nerve

    • Functions:

    Facial e"0ressions&

     aste sensation5anterior 2-6

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    CN '##: Facial Nerve

    • 1esion  *ellIs (als$

    • Causes: – 'iral or bacterial

    infection

     – 9aa,e to the nerve b$traua& tuors + stro;e

    • CN '## lesion also

    causes:- 9r$ corneaJ loss of taste on

    anterior t.o third ofton,ue=

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    CN '##: Clinical 8"aination

    10 C#ec "or "acialexpression

    i= Raise both e$ebro.s

    ii= Fro.niii= Close both e$es

    ti,htl$

    iv= Sho. both u00er

    and lo.er teethv= Sile

    vi= (u! out both chee;s

    2= Chec; for tastesensation

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    CN '###: 'estibulocochlearNerve

    • Sensor$ cranialnerve

    • 2 branches:

    I0 Vesti+$lar Carr$ i0ulsesfore,$ili+ri$m

    II0 Coc#lear  Carr$ i0ulsesfor #earin

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    CN '###: 'estibulocochlearNerveLesion to vesti+$lar+ranc#

     – 'erti,o

     – Ata"ia

     –  N$sta,us

    Lesion to coc#lear+ranc#

    initus&

    9eafness

    Causes:- raua-

     Middle earinfection- 1esions

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    CN '###: Clinical 8"aination

    earin, function

    E= Khis0er

    2= RinneIs est

    = KeberIs test

    'estibular function

    E= Chec; the 0atienthistor$  ,iddiness&dizziness& verti,o

    2= Rober,Is test= N$sta,us

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    CN #): Llosso0har$n,ealNerve

    • 1esions:

    i= %ysp#aia 59icult$ in

    s.allo.in,6ii= Aptylia 59ecrease salivasecretion6

    iii= Ae$sia 51ossof taste sensation6

    iv= oarseness

    v03lossop#aryneal ne$ralia

    Re0eatede0isodes of severepain in the ton,ue&throat& ear& and

    tonsils& lastin, froa fe. seconds to afe. inutesCauses of 1esion:

     raua& (ressin,

    of blood vessels&

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    CN #): Clinical 8"aination

    E= aste sensation5(osteriorl$6

    2= La, ree"

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    CN ): 'a,us Nerve

    • Mi"ed nerve

    • Kidel$ distributed in the head& nec;&thora" and abdoen

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    CN ): 'a,us Nerve

    • Lesion:1oss of 0har$n,eal + 0alatal ree"

    Lastric acid secretion& ,all bladder e0t$in,

    9$s0ha,ia ach$cardia& i0airent to blood 0ressure

    re,ulation

    3vula deviates to the health$ side(aral$sis to the vocal cords

     a0honia

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    CN ): 'a,us Nerve

    • Causes of lesion:

    Mass in the 0osterior fossa

    *on$ fracture daa,e the e"itfro ju,ular foraen

    Neuritis 5e,: her0es zoster6

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    CN ): Clinical 8"aination

    E= Observe the arch of 0alate + uvula.hen the 0atient sa$ aaahI

    2= La, ree"

    = 'isceral function

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    CN )#: Accessor$ Nerve

    • Motor cranial nerve

    • 2 %bres: Cranial %bre + S0inal %bre

    S0inal %bre has 2 0arts: – Cranial 0ortion s.allo.in, oveent

    5lar$n"& 0har$n"& soft 0alate

     –  S0inal 0ortion  ead + shoulder

    oveents 5sternocleidoastoid +tra0ezius uscle6

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    CN )#: Accessor$ Nerve

    Lesions mayca$se:

    - #nabilit$ to raise

    shoulders

     droo0in, ofshoulder

    - 9icult$ to turn

    head

    Ca$ses o" Lesion:

    - Mass lesion at thebase of the s;ull

    - #nterru0tion ofnerve due to

    co0lication ofl$0h node bio0s$

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    CN )#: Clinical 8"aination

    •  ra0ezius + sternocleidoastoiduscles

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    CN )##: $0o,lossal Nerve

    • Motor cranial nerve

    • Functions:Moveent of

    ton,ue& assist ins0eech +s.allo.in,

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    CN )##: $0o,lossal Nerve

    Lesion mayprod$ce:

    - 9$sarthria

    - 9$s0ha,ia- Atro0h$ +

    .ea;ness ofton,ue

    Ca$ses o" lesion:

    -

    *on$ fracture- Mass lesion

    - Con,enitalalforation 5rare6

    - Carotid dissection

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    CN )##: Clinical 8"aination

    • #ns0ect for ton,ue atro0h$&fasciculation or as$etr$

    • Chec; for the stren,th of the ton,ueuscles

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    Conclusion

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    References

    • (rinci0les of Anato$ + (h$siolo,$& Eth 8dition&Lerard ?= ortora + *r$an 9erric;son

    • Fundaentals of Neurolo,$& Mar; Muenthaler&

    einrish Mattle .ith 8than aub& #nternational8dition

    •  e"tboo; of (h$sical (h$siolo,$& L (al + (ravati

    (al& 2nd

     8dition

    • Current Medical 9ia,nosis + reatent5CM96&ierne$& Mc(hee + (a0ada;is 1an,e& 4rd