course outline biochem dph 1
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8/13/2019 Course Outline Biochem Dph 1
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COURSE OUTLINE
1. Course Code: BIC 104
Course Title: MEDICAL BIOCHEMISTRY
Contact Hours: 99
2. Introduction; Biochemistry is the study o the chemic!" com#ositio$ o "i%i$& m!tter !$d the ch!$&es th!t occur i$ it' Such
ch!$&es u$der $orm!" co$ditio$s !re reerred !s (ei$& #hysio"o&ic!" !$d i$ !($orm!" co$ditio$s #!tho"o&ic!"'
The course !ims !t e$!("i$& the tr!i$ee to u$derst!$d the (iochemic!" #ri$ci#"es !$d thereore #re#!res the tr!i$ee to u$dert!)e other
re"!ted courses *ithi$ the #h!rm!cy #ro&r!m'
3. General O!ecti"es:
At the e$d o the course the tr!i$ee shou"d (e !("e to+
A##reci!te *h!t (iochemistry is !$d the (!sic structure o ! "i%i$& ce"" !$d ho* it is or&!$i,ed to co$duct its ch!r!cteristic
chemic!" u$ctio$s'
-$derst!$d the structur!" e"eme$ts o c!tr(ohydr!tes. #rotei$s !$d "i#ids !$d their i$ter!ctio$s *ith other sm!"" mo"ecu"es'
Ac/uire )$o*"ed&e o$ trhe $!ture o e$,ymes !$d the #rocesses o e$,yme c!t!"ysis !s the (!sis o (iochemic!"
tr!$sorm!tio$ms o ce""u"!r su(st!$ces micro !$d m!cro mo"ecu"es'
Com#rehe$d the (iochemic!" re!ctio$s *hich the micro !$d m!cro mo"ecu"es u$der&o *ithi$ the or&!$ism so !s to m!i$t!i$
homeost!sis2 &ro*th !$d m!tur!tio$'
De%e"o# u$derst!$di$& o the structur!" e"eme$ts o chromosomes !$d their u$ctio$s i$ $orm!" !$d !($orm!" st!tes'
#. Course Sc$edule:
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S%LL&'US TO(IC CONTENT HOURS )EE*
1' i$troductio$ 3sco#e o (iochemistry
3micromo"ecu"es
3m!cromo"ecu"es
3or&!$e"es
3ce"" structure !$d u$ctio$
' c!r(ohydr!tes 3dei$itio$
3c"!ssiic!tio$
• Mo$os!cch!rides
• O"i&os!cch!rides
• 5o"ys!cch!rides
3i$testi$!" !(sor#tio$'
6' #rotei$s 3dei$itio$• 5rotei$s
• 5e#tides
• Ami$o !cids
3!mi$o !cids
3#e#tides
3#rotei$s
• Co$orm!tio$
•
C"!ssiic!tio$• De$!tur!tio$
• I$testi$!" !(sor#tio$
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?' Li#id Met!(o"ism 3"i#id di&estio$
3c!t!(o"ism o &"ycero" 8 !tty !cids
3!$!(o"ism o &"ycero". !tty !cids. tri&"ycerides !$d #hos#ho"i#ids
3)eto&e$esis
3cho"estero" met!(o"ism
3re&u"!tio$ o "i#id met!(o"ism
3!($orm!"ities o "i#id met!(o"ism
9' #rotei$ met!(o"ism 3#rotei$ di&estio$
3!mi$o !cid #oo"
3tr!$s!mi$!tio$. de!mi$!tio$. !$d dec!r(o<y"!tio$
3&"yco&e$ic 8 )eto&e$ic !mi$o !cids
3!te o !mmo$i!
• -re! cyc"e
• Biosy$thesis o $o$ esse$ti!" !mi$o !cids
• Biosy$thesis o (io&e$ic !mi$es
• Some c"i$ic!""y im#ort!$t !mi$o!cid met!(o"ites
10' mo"ecu"!r &e$etics 3dei$itio$ o $uc"eic !cids
3deo<yri(o$uc"eic !cid 8 ri(o$uc"eic !cid
3DA re#"ic!tio$
3tr!$scri#tio$
3tr!$s"!tio$
3summ!ry o #rotei$ sy$thesis
3#oi$t mut!tio$s
3chromosomes !$d chromosomes #!tho"o&y
3heredit!ry disisorders o met!(o"ism
+. Instructional ,aterials-eui/0ents
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