Corneal collagen cross-linking (CXL)

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Corneal collagen cross-linking (CXL). Alireza Peyman, MD Isfahan University of Medical Sciences. CXL with riboflavin and ultraviolet-A irradiation introduced in 1998 Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res. 1998;66:97103. Indications. - PowerPoint PPT Presentation

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Corneal collagen cross-linking(CXL)Alireza Peyman, MDIsfahan University of Medical Scienceshttp://www.drpeyman.ir CXL with riboflavin and ultraviolet-A irradiation introduced in 1998Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res. 1998;66:97103.

http://www.drpeyman.ir IndicationsCornea ectasiasKCPMD

Iatrogenic ectasiasPost-LASIK keratectasia

Infectious ulcersCorneal edemahttp://www.drpeyman.ir Importance of age of the patient 40 http://www.drpeyman.ir TechniqueUsing a wavelength of 370 nm with an accumulated irradiance of 5.4 J/cm2 ensures that the exposure of all structures is below harmful levelshttp://www.drpeyman.ir Epi-Off

Epi-On

Penetration of riboflavinRole of oxygen

http://www.drpeyman.ir IrradiationConventional

Accelerated

Pulsedhttp://www.drpeyman.ir ComplicationsSignificant haze

CTK

Infection

http://www.drpeyman.ir CombinationsCXL + ICRSCXL + Microwave keratoplasty (Keraflex)

CXL + PRKCXL + LASIKhttp://www.drpeyman.ir Is repeat CXL helpful?http://www.drpeyman.ir

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