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C O N T I N U I N G M E D I C A L E D U C A T I O N

Department of Otolaryngology – Head and Neck Surgery presents

Controversies in HPV and Head and Neck Cancer

This activity has been approved for AMA PRA Category 1 Credits™

October 25-26, 2013Gaylord National Resort and Convention Center National Harbor, Maryland

Located in the Washington D.C. area

DescriptionHuman papillomavirus (HPV) is responsible for a subset of head and neck cancers which have distinct epidemiological, molecular, pathological and clinical features. The knowledge base in this multidisciplinary field is quickly developing. Commensurate with the rapid pace of advancements in the field, additional clinical management questions arise. The goal of this activity is to discuss the current controversies in the diagnosis, work-up, and treatment strategies.

ObjectivesAfter attending this activity, the participant will demonstrate the ability to:

Describe the changing trends and new risk factors associated with the development of head and neck cancer.

Explain diagnostic tests utilized to diagnose HPV-associated head and neck cancers.

Discuss the novel treatment strategies, both surgical and non-surgical, which are being developed to target the unique biology of these cancers.

Recognize the specific rehabilitation needs of oropharyngeal cancer patients.

Who Should AttendThis activity is intended for both a national and international audience comprised of academic and community head and neck surgeons, medical oncologists, radiation oncologists, oral and maxillofacial surgeons, dentists, nurse practitioners, nurses, physician assistants, and speech language pathologists.

Accreditation StatementThe Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credit Designation StatementThe Johns Hopkins University School of Medicine designates this live activity for a maximum of 11.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other CreditsAmerican Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credit™ from organizations accredited by the ACCME.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 11.25 hours of Category 1 credit for completing this program.

The Johns Hopkins University has approved this activity for 11.25 contact hours for non-physicians.

Policy on Speaker and Provider DisclosureIt is the policy of the Johns Hopkins University School of Medicine that the speaker and provider disclose real or apparent conflicts of interest relating to the topics of this educational activity, and also disclose discussions of unlabeled/unapproved uses of drugs or devices during their presentation(s). The Johns Hopkins University School of Medicine OCME has established policies in place that will identify and resolve all conflicts of interest prior to this educational activity. Detailed disclosure will be made in the activity handout materials.

General InformationRegistrationOctober 25, 2013 7:15 a.m. – 5:00 p.m. October 26, 2013 7:15 a.m. – 8:00 a.m.

LocationGaylord National Resort and Convention Center 201 Waterfront Street National Harbor, Maryland 20745

FeesREGISTRATION CUT-OFF DATE: October 19, 2013

Methods of Payment: Payment by check or credit card must accompany the registration form prior to the activity. On-site payments by credit card only. Foreign payments must be by credit card or with a U.S. Dollar World Money Order. The registration fee includes instructional materials, continental breakfasts, refreshment breaks and lunches. Before After August 1 August 1

Physicians .................................................................................................. $400 ........................... $450Residents*/Fellows*/Allied Health Professionals ................. $225 ........................... $300*with verification of statusYou will receive a confirmation by e-mail if you have provided your e-mail address. Otherwise confirmation will be sent by mail. If you have not received it by October 19, 2013, call (410) 502-9634 to confirm that you are registered. A certificate of attendance will be sent by December 11, 2013 to the e-mail address you provide on the registration form. The Johns Hopkins University reserves the right to cancel or postpone any activity due to unforeseen circumstances. In this event, the University will refund the registration fee but is not responsible for travel expenses. Additionally, we reserve the right to change the venue to a comparable venue. Under such circumstances registrants will be notified as soon as possible.

Late Fee and Refund PolicyA $50 late fee applies to registrations received after 5:00 p.m. EST on October 19, 2013. A handling fee of $50 will be deducted for cancellation. An additional fee may apply for cancellation of other events, including workshops and social activities. Refund requests must be received by fax or mail by October 19, 2013. No refunds will be made thereafter. Transfer of registration to another Johns Hopkins conference in lieu of cancellation is not possible.

Hotel and Travel InformationGaylord National Resort and Convention Center 201 Waterfront Street National Harbor, Maryland 20745 Reservations: (301) 965-4000 Toll-Free: (877) 491-0468Web Site: http://www.marriott.com/hotels/travel/wasgn-gaylord-national-resort-and-convention-center/

Rooms are available on a first come, first served basis. We recommend making your reservation arrangements as soon as possible.

Your may make your reservation by calling (877) 491-0468 and mentioning the Johns Hopkins University School of Medicine HPV Head and Neck Cancer. You may also make reservations online by following this link: https://resweb.passkey.com/go/jhu2013

The special group rate is $209, single or double, plus tax and $18 resort fee. On-site parking is available for $24 per day self-park or $35 per day valet. Check-in time is 3:00 p.m. Check-out time is 12:00 p.m.

EvaluationA form will be available to attendees to evaluate each session and each speaker’s presentation, as well as to identify future educational needs.

Outcomes surveyA survey will be sent to all physician attendees within three months post activity to assist us in determining what impact this activity had on the attendee’s practice.

Emergency CallsOn the day of this activity only, October 25-26, 2013, direct emergency calls to (301) 965-4000 and ask that a message be sent to the Johns Hopkins registration desk. Messages will be posted for participants.

Americans with Disabilities ActThe Johns Hopkins University School of Medicine fully complies with the legal requirements of the ADA and the rules and regulations thereof. Please notify us if you have any special needs.

To Register or for Further Information:Register Online (credit card and eCheck) www.HopkinsCME.eduRegister by Phone (credit card only) (410) 502-9634General Information (410) 955-2959E-mail the Office of CME cmenet@jhmi.eduActivity Website http://www.hopkinscme.edu/CourseDetail.aspx/80030297C

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Friday, October 25, 2013 7:15 - 8:00 Registration and Continental Breakfast 8:00 - 8:10 Welcome and Introduction

David Eisele, MDEpidemiologyModerator: Gypsyamber D’Souza, PhD, MHS 8:10 - 8:30 Are Sexual Behaviors Relevant to Head and Neck

Cancer? Carole Fakhry, MD, MPH

8:30 - 8:50 Is the Burden of HPV-Related Head and Neck Cancers Increasing in the U.S. and Abroad? Anil Chaturvedi, PhD

8:50 - 9:10 Will Current Vaccination Programs Impact the Epidemiology of HPV-Related Head and Neck Cancer? Gypsyamber D’Souza, PhD, MHS

9:10 - 9:30 Refreshment Break 9:30 - 9:50 Are HPV-Driven Head and Neck Cancers

Preventable? Aimee Kreimer, PhD

9:50 - 10:10 Are Partners at Risk for Developing HPV-Related Diseases? Gypsyamber D’Souza, PhD, MHS

10:10 - 10:40 HPV and Racial Disparities in Head and Neck Cancer Kevin Cullen, MD

10:40 - 11:00 Refreshment Break 11:00 - 11:10 The Risk of Head and Neck Cancers in HIV-Infected

Individuals Meredith Shiels, PhD

11:10 - 11:30 Can We Use Oral Pap Smear and Oral Rinses for Early Detection of HNSCC? Carole Fakhry, MD, MPH

11:30 - 12:00 Questions and Answers 12:00 - 1:00 LunchDiagnosis and Clinical DetectionModerator: Wayne Koch, MD 1:00 - 1:20 The Genetics of HPV-Associated HNSCC

Nishant Agrawal, MD 1:20 - 1:40 High Intratumor Heterogeneity Predicts Poor

Outcome in Head and Neck Cancers James Rocco, MD, PhD

1:40 - 2:00 HPV-Based Detection and Surveillance for Oropharynx Cancer Joseph Califano, MD

2:00 - 2:20 The Morphologic Profile of HPV-Related HNSCC: Implications for Diagnosis, Prognosis and Clinical Management William Westra, MD

2:20 - 2:50 Refreshment Break 2:50 - 3:10 HPV Detection in Clinical Samples: Why, When, How

and What Next? William Westra, MD

3:10 - 3:30 HPV-Related Cancer in Extra-Oropharyngeal Sites Justin Bishop, MD

3:30 - 3:50 Refreshment Break 3:50 - 4:10 The Unknown Primary

David Eisele, MD

4:10 - 4:30 Imaging of HPV-Related Head and Neck Cancer Rathan Subramaniam, MD, PhD, MPH

4:30 - 4:50 Distant Metastasis and Locoregional Recurrence Patterns of HPV-Associated Oropharyngeal Squamous Cell Young Kim, MD, PhD

4:50 - 5:00 Questions and Answers 5:00 Adjourn

Saturday, October 26, 2013 7:15 - 8:00 Registration and Continental Breakfast 8:00 - 8:10 Welcome

Sara Pai, MD, PhDTreatment Moderators: Harry Quon, MD, Jeremy Richmon, MD and Young Kim, MD, PhD 8:10 - 8:30 What is the Optimal Treatment for

HPV-Associated OSCC? Harry Quon, MD

8:30 - 8:50 The Role of Surgery in Oropharyngeal Cancer Jeremy Richmon, MD

8:50 - 9:10 Does Cetuximab Work in Patients with HPV-Positive HNSCC? Christine Chung, MD

9:10 - 9:30 Is There a Role for Post-Treatment Neck Dissection? Christine Gourin, MD, MPH

9:30 - 9:45 Refreshment Break 9:45 - 10:15 Peptide-Based Approaches for the Prevention and

Treatment of Head and Neck Cancer Scott Strome, MD

10:15 - 10:45 Going Viral: Immunotherapy Against HPV-Associated Oropharynx Cancer Robert Ferris, MD, PhD

10:45 - 11:15 Novel Therapies to Enhance Immunologic Responses Against Head and Neck Cancers Sara Pai, MD, PhD

11:15 - 11:30 Refreshment Break RehabilitationModerator: Christine Gourin, MD, MPH 11:30 - 12:00 PEG or Not PEG, That is the Question:

Pros and Cons of Using Feeding Tubes During Chemoradiation for Oropharyngeal Cancer Patients Donna Tippett, MPH, MA, Kim Webster, MA, MS, CCC-SLP

12:00 - 12:15 Trismus in Oropharyngeal Cancer Patients Undergoing Concurrent Chemoradiation: Incidence and Treatment Barbara Messing, MA, CCC-SLP, BRS-S

12:15 - 12:30 Enhancing Adherence to Speech and Swallowing Therapy Heather Starmer, MA, CCC-SLP

12:30 - 12:45 Head and Neck Cancer Related Lymphedema: Evidence and Controversies Alan Kimmel, MD

12:45 - 1:00 Closing Remarks 1:00 Adjourn - Please complete and return the Evaluation and Credit

Report Forms. The Registration Desk will remain open during conference hours.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality and scientific integrity of this CME activity.This schedule is subject to change.

Controversies in HPV and Head and Neck Cancer

ProgramCo-Directors

Carole Fakhry, MD, MPHAssistant Professor of Otolaryngology-Head and Neck Surgery

Sara Pai, MD, PhDAssociate Professor of Otolaryngology-Head and Neck Surgery

Hopkins Faculty

Nishant Agrawal, MDAssociate Professor of Otolaryngology-Head and Neck Surgery

Justin Bishop, MDAssistant Professor of Pathology

Joseph Califano, MDProfessor of Otolaryngology-Head and Neck Surgery

Christine Chung, MDAssociate Professor of Oncology

Gypsyamber D’Souza, PhD, MHSAssociate Professor of Epidemiology

David Eisele, MDAndelot Professor and Director of Otolaryngology-Head and Neck Surgery

Christine Gourin, MD, MPHAssociate Professor of Otolaryngology-Head and Neck Surgery

Rafael Guerrero-Preston, PhD Assistant Professor of Otolaryngology-Head and Neck Surgery

Young Kim, MD, PhDAssistant Professor of Otolaryngology-Head and Neck Surgery

Wayne Koch, MDProfessor of Otolaryngology-Head and Neck Surgery

Harry Quon, MDAssociate Professor of Radiation Oncology and Molecular Radiation Sciences

Jeremy Richmon, MDAssistant Professor of Otolaryngology-Head and Neck Surgery

Heather Starmer, MA, CCC-SLPAssistant Professor of Otolaryngology-Head and Neck Surgery

Rathan Subramaniam, MD, PhD, MPHAssociate Professor of Radiology and Radiology Sciences

Donna Tippett, MPH, MAAssistant Professor of Otolaryngology–Head and Neck Surgery

Kim Webster, MA, MS, CCC-SLPAssistant Professor of Otolaryngology - Head and Neck Surgery

William Westra, MDProfessor of Pathology

Guest Faculty

Anil Chaturvedi, PhDInvestigatorNational Institutes of HealthDivision of Cancer Epidemiology and GeneticsBethesda, Maryland

Kevin Cullen, MDMarlene and Stewart Greenebaum Distinguished Professor of OncologyGreater Baltimore Medical CenterBaltimore, Maryland

Robert Ferris, MD, PhDEndowed Professor of Otolaryngology - Head and Neck SurgeryUniversity of PittsburghPittsburgh, Pennsylvania

Alan Kimmel, MDMedical Director, Greater Baltimore Center for Rehabilitation MedicineGreater Baltimore Medical CenterBaltimore, Maryland

Aimee Kreimer, PhDInvestigatorNational Institutes of HealthDivision of Cancer Epidemiology and GeneticsBethesda, Maryland

Barbara Messing, MA, CCC-SLP, BRS-SBoard Recognized Specialist in Swallowing Disorders

James Rocco, MD, PhD Associate Professor of Otology – LaryngologyHarvard Medical SchoolBoston, Massachusetts

Meredith Shiels, PhDResearch FellowNational Institutes of HealthDivision of Cancer Epidemiology and GeneticsBethesda, Maryland

Scott Strome, MDProfessor and Chairman of Otorhinolaryngology-Head and Neck SurgeryUniversity of Maryland School of MedicineBaltimore, Maryland

Faculty

last name first name m.i.

highest degree primary specialty Hopkins Faculty/Staff Only – JHED ID:

mailing address

city state ZIP + 4 code country

daytime telephone fax number

e-mail / / / / / / / / / / / / / / / / / / /

Registration Form Course Number 80030297

Controversies in HPV and Head and Neck Cancer

October 25-26, 2013To Register : Online (credit card and eCheck): www.HopkinsCME.edu By fax: (866) 510-7088 By phone (credit card only): (410) 502-9634

Or mail this form to the Johns Hopkins University, Office of Continuing Medical Education, P.O. Box 64128, Baltimore, Maryland 21264-4128. Include check payable to HOPKINS/80030297, or include credit card information below.

PAYMENT MUST ACCOMPANY FORM TO CONFIRM YOUR REGISTRATION.

I am a Johns Hopkins speaker for this activity.Please type or print clearly:

You will receive a confirmation notice and your attendance certificate by e-mail if you provide your e-mail address.

Check here if you wish to receive e-mail notices about upcoming CME activities.

What do you hope to learn by attending this activity?

_______________________________________________________________

Please notify us if you have any special needs.

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Registration Fees: Before After August 1 August 1

Physicians ........................................................................................... $400 ........................... $450

Residents*/Fellows*/Allied Health Professionals .......... $225 ........................... $300 *with verification of status

For registrations received after 5:00 p.m. EST on October 19, 2013, include a $50 late fee. On-site registrations are payable only by credit card.

Total amount enclosed $ ___________.

Payment Type:

JHU Faculty/Staff Only: If you are using your Tuition Remission Benefit or an ION budget, please complete this registration form and return with appropriate payment processing form to OCME, Turner 20.

Forms can be found on-line at http://www.hopkinscme.edu/Resources/resources.aspx.

Check (See instructions on top of form.)

Credit Card: VISA MASTERCARD DISCOVER AMEX

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Name on Card _______________________________________________ Please print clearly

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