509

Mutation Research, 74 (1980) 509--511 © Elsevier/North-Holland Biomedical Press

CONTENTS

VOLUME 74 (1980)

Definition of condit ions for the detection of genotoxic chemicals in the adult rat-liver epithelial cell /hypoxanthine--guanine phosphoribosyl transferase (ARL/HGPRT) mutagenesis assay by Charles Tong and Gary M. Williams (Valhalla) . . . . . . . . . . . . . . . . . . . 1--9

A micronucleus technique for detecting clastogenic effects of mutagens/carcino- gens (DEN, DMN) in hepatocytes of rat liver in vivo by A.D. Tates, I. Neuteboom, M. Hofker and L. den Engelse (Leiden and Amsterdam) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11--20

Validation of condit ions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells by Larry H. Thompson, Susan Fong and Kerry Brookman (Livermore) . . . . . 21--36

Resistance to methyl mercaptopurine riboside in cultured hamster cells Preliminary characterization of resistant cells and conditions affecting their selection in quantitative mutat ion studies by John Thacker (Harwell) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37--59

Analysis in vivo of sister-chromatid exchange in mouse bone-marrow and sali- vary-gland cells by Pedro Morales Ramfrez (M~xico) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61--69

Meeting Report Second European Workshop on bacterial in vitro mutagenicity test systems

(Ames Test Meeting 1979) by J.P. Seiler, Ina E. Mattern, M.H.L. Green and D. Anderson (Waedenswfl, Rijswijk, Brighton and Macclesfield) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71--75

A review of the coordinated research effort on the comparison of test systems for the detect ion of mutagenic effects, sponsored by the E.E.C. by I.-D. Adler (Neuherberg) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77---93

Feasibili ty of testing DNA repair inhibitors for mutagenicity by a simple method by Aris S. Sideropoulos, Susan M. Specht and Mark T. Jones (Pittsburgh) . . . 95--105

The E. coli A~ assay A quantitative procedure for diffusible and non-diffusible chemicals by Julie Hyman, Zev Leifer and Herbert S. Rosenkranz (Valhalla) . . . . . . . .

A new, sensitive and simple bioluminescence test for mutagenic compounds by S. Ulitzur, I. Weiser and S. Yannai (Haifa) . . . . . . . . . . . . . . . . . . . . . .

Quantitative determination of half:lifetimes and mutagenic concentrations of chemical carcinogens using a diffusion bioassay by Tamara E. Awerbuch and Anthony J. Sinskey (Cambridge) . . . . . . . . . .

The Salmonella mutagenici ty assay: Reproducibi l i ty by Carol Cheli, Donna DeFrancesco, Lynn A. Petrullo, Elena C. McCoy and Herbert S. Rosenkranz (Valhalla) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Gesellschaft fiir Umwelt-Mutationsforschung e. IT. (GUM) Abstracts of papers presented at the 5th Meeting, October 18th and 19th, 1979,

Rheinfelden/Aargau (Switzerland) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . The European Environmental Mu tagen Society Abstracts of papers presented at the 9th Annual Meeting of the European

107--111

113--124

125--143

145--150

151--166

510

Environmental Mutagen Society, September 30th--October 5th, 1979, Tu~epi-Makarska (Yugoslavia) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Influence of DNA adenine methylation dam mutations and of plasmid pKM 101 on the spontaneous and induced mutability of certain genes in Esche- richia coli K12 by G.R. Mohn, N. Guijt and B.W. Glickman (Leiden) . . . . . . . . . . . . . . . .

Detection of mutagen-induced lesions in isolated DNA using a new Bacillus subtilis transformation-based assay by Robert A. Philips, Stanley A. Zahler and Anthony J. Garro (New York) . .

The analysis of fluctuation tests by R.I. Gilbert (Swansea) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

A mutagenic.test in vivo combining the intrasanguineous and urinary assays by C. Bauer, C. Corsi, C. Leporini, R. Nieri and N. Capetola (Pisa) . . . . . . . .

Different test systems in Aspergillus nidulans for the evaluation of mitotic gene conversion, crossing-over and non-disjunction by M. de Bertoldi and M. Griselli (Pisa) . . . . . . . . . . . . . . . . . . . . . . . . . . .

Mutagenesis of lambda phage by t/f-expression or host-irradiation functions is largely independent of damage in the phage DNA by A. yon Wright and B.A. Bridges (Brighton) . . . . . . . . . . . . . . . . . . . . .

Correlation between particulate effluent mutagenicity and increased carbon monoxide concentration in a fluidized-bed coal combustor by H.E. Kubitschek, D.M. Williams and F.R. Kirchner (Argonne) . . . . . . . . .

The Environmental Mutagen Society of Japan Titles of Abstracts presented at the 8th Annual Meeting, November 27--28,

1979, Yumoto, Kanagawa-ken (Japan) . . . . . . . . . . . . . . . . . . . . . . . . . . Mutagenic activation of dibromomethane and diiodomethane by mammalian mi-

crosomes and glutathione S-transferases by P.J. van Bladeren, D.D. Breimer, G.M.T. Rotteveel-Smijs and G.R. Mohn (Leiden) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Towards an improved micronucleus test Studies on 3 model agents, mitomycin C, cyclophosphamide and dimethyl- benzanthracene by Michael Salamone, John Heddle, Earl Stuart and Morris Katz (Downsview)

Chemical carcinogen induction of DNA-repair synthesis in human peripheral blood monocytes by Robert S. Lake, Melvin L. Kropko, Sandra McLachlan, Mary R. Pezzutti, Robert H. Shoemaker and Howard J. Igel (Akron) . . . . . . . . . . . . . . . . . .

Do induced sperm-head abnormalities in mice specifically identify mammalian mutagens rather than carcinogens? by J.C. Topham (Macclesfield) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Stability of $9 during frozen storage in Salmonella/S9 assays by Kunie Yoshikawa, Takehiko Nohmi, Ayumu Nagahara, Yoshiyuki Inokawa and Motoi Ishidate Jr. (Tokyo) . . . . . . . . . . . . . . . . . . . . . . . . .

The transplacental micronucleus test by Carol J. Stoyel and A.M. Clark (Bedford Park) . . . . . . . . . . . . . . . . . . .

Letter to the Editor The Salmonella mutagenicity assay: Reproducibility

by M.J. Peak, Bruce S. Hass and Suzanne S. Dornfeld (Argonne) . . . . . . . . . Report 1979 local activity reports (EEMS) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Meeting. Report International Workshop on Short-term Tests for Chemical Carcinogens Vancouver,

B.C., Canada, August 22--24, 1979 by H.F. Stich and R.H.C. San (Vancouver) . . . . . . . . . . . . . . . . . . . . . . .

Abstracts Chemicals and Genes

4th Annual Australian and New Zealand Environmental Mutagen Society Meeting, Sidney, Jan. 31--Feb. 1¢ 1980 . . . . . . . . . . . . . . . . . . . . . . . . . .

167--253

255--265

267--281

283--289

291--302

303--324

325--328

329--333

335--339

341--346

347--356

357--377

379--387

389--391

393--398

399--400

401--409

411--414

415--427

Announcement Differential effects of acetone or Aroclor 1254 pretreatment on the microsomal

activation of dimethylnitrosamine to a mutagen by Steven M. Haag and I. Glenn Sipes (Tucson) . . . . . . . . . . . . . . . . . . . .

Quantitative measures of mutagenicity and mutability based on mutant yield data by Friederike Eckardt (Neuherberg) and Robert H. Haynes (Toronto) . . . . .

Quantitation of induced mutation in Dictyostelium discoideum Characterization and u~e of a methanol-resistance mutation assay by Gregory Podgorski and R.A. Deering (University Park) . . . . . . . . . . . . .

Identification of carcinogens by mutagenicity for Arabidopsis by G.P. R~dei, Magdolna M. R~dei, William R. Lower (Columbia) and Shahbeg Sandhu (Research Triangle Park) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Sister-chromatid exchange induction by carcinogens in HTC cells An in vitro system which does not require addition of activating factors by R. Dean, G. Bynum, D. Kram and E.L. Schneider (Baltimore) . . . . . . . . .

Promutagen activation by rodent-liver postmitochondrial fractions in the L5178Y/TK cell mutation assay by David E. Amacher and Gail N. Turner (Groton) . . . . . . . . . . . . . . . . . .

Repeated mutagenesis and the selection of recessive and dominant mutations in cultured mammalian cells by Radhey S. Gupta (Hamilton) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Contents, Vol. 74 (1980) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Author Index, Vol. 74 (1980) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Sub]ectIndex, Vol. 74 (1980) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Erratum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

511

429

431--438

439--458

459--468

469--475

477--483

485--501

503--508

509--511

512--516

517--526

526