GROUND SUBSTANCE

COLOURLESS TRANSPARENT VISCOUS GEL PRESENT B/W CELLS & FIBERS OF CONNECTIVE TISSUE

COMPOSITION

PROTEOGLYCANS

GAGS + PROTEIN CORE

(90-95%) + (5%)

GLYCOPROTEINS

PROTEINS + CHO

(90-95%) + (5%)

PROTEOGLYCANS

GAGS COVALENTLY BOUND PROTEIN CORE

BASOPHILIC

HYDRATED GEL

GROWTH FACTORS

GAGS

UNBRANCHED LONG CHAIN POLY SACCHARIDES

REPEATING DISACCHARIDE UNITS

URONIC ACID + HEXOSAMINE + -VE CHARGED UNIT( sulphate, carboxyl, hydroxyl)

-VE CHARGED SO4 0R CARBOXYL

BASOPHILIC

HYDRATED GEL

SULPHATED & NON SULPHATED

SULPHATED GAG

CHONDROITIN 4 & 6 SO4

CARTILAGE

KERATAN SO4 CORNEA CARTILAGE NUCLEUS

PULPOSUS

INCREASES WITH AGE

DERMATAN SO4

SKIN

HEPARAN SO4 AORTA LUNG LIVER BASAL

LAMINA

NONSULPHATED

HYALURONIC ACID

LONG CHAIN NON SO4 GAG WITHOUT A PROTEIN CORE

ALL ECM (embryonic & developing)

INTERACTS WITH SPECIFIC RECEPTORS ON THE CELLS

PROTEOGLYCAN AGGREGATE (LINKER PROTEIN)

VISCOUS SOLUTION

GLYCOPROTEINS PROTEIN + CHO

FILAMENTOUS PROTEINS

ADHESIVE PROPERTY

GLCOSYLATED

BINDING SITES FOR

ECM MOLECULES

CELL ADHESION MOLECULES

SIGNALING MOLECULES

FUNCTIONS OF GROUND SUBSTANCE

FILLS SPACES

LUBRICANT

BARRIER

LOOSE C.T.

MOST GENERALIZED CELLULAR, ABUNDANT GROUND

SUBSTANCE & FEW FIBERS FIBROBLAST, FAT CELL & WANDERING

CELLS VISCOUS GEL LIKE GROUND SUBSTANCE THIN MESH WORK OF COLLAGEN &

ELASTIC FIBER HIGHLY VASCULAR SUPERFICIAL FACIA,BENEATH EPITHELIUM FUNCTIONS

DENSE C.T.REGULAR & IRREGULAR

DENSE PACKING OF FIBER

FEW CELLS & LITTLE GROUND SUBSTANCE

LIMITED VASCULAR SUPPLY

REGULAR & IRREGULAR

DENSE IRREGULAR C.T.

THICK BUNDLES OF COLLAGEN

RUNNING IN ALL DIRECTIONS

AREAS SUBJECT TO CONSIDREABLE MECHANICAL STRESS

DENSE REGULAR C.T.

DENSELY PACKED // FIBERS

CORDS BANDS OR SHEETS

TENDONS LIGAMENT & APONEUROSES

GREAT TENSILE STRENGTH

TENDON

CORD LIKE

WHITE INEXTENSIBLE

CELLS IN ROWS // FIBER

TENDON CELL

ENDOTENDINEUM, EPITENDINEUM

APONEUROSES

Sheet of // fibers, adjacent layer at angle

LIGAMENTS

Similar to tendon less regular, fibrous or yellow elastic

C.T with SPECIAL PROPERTIES

ADIPOSE, RETICULAR, PIGMENTED

ADIPOSE TISSUE

FAT STORING TISSUE

ADIPOCYTES

RICH BLOOD SUPPLY

WHITE & BROWN ADIPOSE TISSUE

WHITE ADIPOSE TISSUE

UNILOCULAR ADIPOCYTES (SIGNET

RING)

SPHERICAL POLYHEDRAL

CONDENSED LIPID + VIMENTIN

ORGANIC SOLVENT XYLENE

ENERGY STORAGE INSULATION & CUSHIONING OF VITAL ORGANS

LEPTIN & CYTOKINES

LIPOMAS & LIPOSARCOMAS

BROWN ADIPOSE TISSUE

SMALLER, MULTILOCULAR, NUCLEUS ROUND ECCENTRIC OF CAPILLARIES

RICH SUPPLY

> MITOCHONDRIA WITH CYTOCHROME OXIDASE

< GOLGI, r ER & s ER

RETICULAR C.T.

RETICULAR FIBERS & RETICULAR CELLS

DELICATE NETWORK

RETICULAR CELLS, CYTOPLASMIC PROCESSES, PARTIALLY COVER THE RETICULAR FIBERS, MONONUCLEAR PHAGOCYTIC SYSTEM

HEMATOPOIETIC & LYMPHOID ORGANS