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- State Secretary of the Ministry of Health, Slovakia - National Cancer Registry, Slovakia / National Health Information Center Conference Prevention of chronic non - communicable diseases and healthy lifestyle 20-21 September 2016, Bratislava

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- State Secretary of the Ministry of Health, Slovakia

- National Cancer Registry, Slovakia / National Health Information Center

Conference „ Prevention of chronic non-communicablediseases and healthy lifestyle“

20-21 September 2016, Bratislava

• Initial source for population’s health conditions tracking – mortality statistics (18th century, Maria Theresia)

• Primary international classification related to causes of death only (1856) and afterwards extended to classification of diseases as well

Life StyleDemographic

evolutionHealth

conditions

↑ risk factors prevalence /

RF precaution

aging, changes of life

expectancy

↑ incurrence/ deaths to

circulatory disease, Tumours,

respiratory disease

• Causes of death reflected predominantly infectious diseases – universal vaccination(since the ‘60s of 20th century) = ↓ infectious diseases / ↓ mortality

• Social/political/economic changes impact on:

60 000 40 000 20 000 0 20 000 40 000 60 000

0

4

8

12

16

20

24

28

32

36

40

44

48

52

56

60

64

68

72

76

80

84

88

92

96

Women 2020 Men 2020Women 2001 Men 2001Women 2010 Men 2010

MEN WOMEN

Indicator

Year

1971 1986 2001 2010 2015Prognosis

in 20201 Trend

Population

( in 1 000)4559 5192 5 379 5 431 5 423 5 510 -

Age structure

(%)

0-14 27,0 26,4 19,1 15,3 15,3 15,51 ↓

15-24 18,7 15,0 17,0 14,3 11,9 9,91↓

25-44 25,1 29,3 29,5 31,4 31,6 30,61 ↑

45-64 20,0 19,8 23,0 26,7 26,9 27,21↑

65-74 6,6 5,6 6,9 7,1 8,5 10,61↑

75+ 2,7 4,0 4,5 5,3 5,7 6,11↑

Source: Statistical Office Slovakia1) Mészaroš, INFOSTAT 2011

10,07

12,1413

13,8614,83 14,92

13,29

15,35

16,6417,47

18,2418,92

0

2

4

6

8

10

12

14

16

18

20

1971 1986 2001 2010 2015 2020 1971 1986 2001 2010 2015 2020Years

MEN WOMEN

Source: Statistical Office Slovakia / Mészaroš, INFOSTAT)

pro

gno

sis

pro

gno

sis

MEN

Age group Year All deaths

proportion on all deaths in %

Circulatory

diseasesCancer Accidents

Respiratory

system

Digestive

system

0-85+1971 23 638 41,6 17,4 11,2 14,7 4,8

2015 27 462 42,2 27,8 8,0 7,9 6,3

35-641971 7 361 37,2 23,4 15,4 9,3 7,1

2015 9 252 32,1 29,4 13,4 5,9 11,0

65+1971 13 399 52,0 16,8 3,0 18,1 3,6

2015 17 293 49,5 27,9 3,4 9,1 3,8

WOMEN

Age group Year All deaths

proportion on all deaths in %

Circulatory

diseases

Cancer AccidentsRespiratory

system

Digestive

system

0-85+1971 19 218 51,7 17,0 4,4 11,8 4,0

2015 26 364 54,3 22,8 3,2 7,2 4,1

35-641971 4 059 39,4 31,8 5,7 6,5 6,2

2015 4 002 24,7 44,1 6,8 6,2 9,3

65+1971 13 660 60,7 13,5 2,9 12,3 3,2

2015 21 951 60,6 19,1 2,3 7,3 3,2

Source: Statistical Office Slovakia

The same opinion had a WHO group of experts, who recommended to establish cancer registers of population based on exact agreed criteria in 1976. Having national register of malignant tumours of its patients made Czechoslovak Republic one of the pioneers in this field (even reporting for oncological patient was compulsory since 1952, there wasn’t a unified population register).

National Cancer Registry in SR (NCR SR) was established in 1976 by doc.MUDr. Ivan Pleško, CSc.

Executive doctors – operational POKO + qualified team NCR SR = high data quality, high international credit (international databases/ publications/ projects).

818 627

1968-2010

135 184

2011-2015*

953 811

1968-2015

* estimate

Summary oncological cases

6 9597 616

8 800

9 92010 635

11 415

12 595

14 915

13 515

5 7996 164 6 911

8 040

9 282

10 336

12 068

14 972

13 522

0

2 000

4 000

6 000

8 000

10 000

12 000

14 000

16 000

1971-1975 1976-1980 1981-1985 1986-1990 1991-1995 1996-2000 2001-2005 2006-2010 2011-2015*

Men Women

* Preliminary data from the database hospitalizedSource: NCR SR

0

100

200

300

400

500

0-85+

incidence mortality

0

100

200

300

400

500

0-85+

incidence mortality

0

500

1000

1500

2000

2500

3000

19

71

-19

75

19

76

-1

98

0

19

81

-19

85

19

86

-1

99

0

19

91

-19

95

19

96

-2

00

0

20

01

-20

05

20

06

-20

10

20

11

-20

15

35-64

incidence mortality

0

500

1000

1500

2000

2500

3000

19

71

-19

75

19

76

-1

98

0

19

81

-19

85

19

86

-1

99

0

19

91

-19

95

19

96

-2

00

0

20

01

-20

05

20

06

-20

10

20

11

-20

15

35-64

incidence mortality

0

500

1000

1500

2000

2500

3000

19

71

-19

75

19

76

-19

80

19

81

-19

85

19

86

-19

90

19

91

-19

95

19

96

-20

00

20

01

-20

05

20

06

-20

10

20

11

-20

15

65+

incidence mortality

0

500

1000

1500

2000

2500

3000

19

71

-19

75

19

76

-1

98

0

19

81

-19

85

19

86

-1

99

0

19

91

-19

95

19

96

-2

00

0

20

01

-20

05

20

06

-20

10

20

11

-20

15

65+

incidence mortality

MEN WOMEN

Source: Deaths - Statistical Office Slovakia / Mortality - National Health Information Center / Incidence – NCR SR

n /

per

10

0 0

00

, W

SR

Diagnosis Sex 1971-1980 1981-1990 1991-2000 2001-2010 2011-2015* Trend

C18-C21

Men 8,7 10,4 13,1 14,5 17,3 ↑

Women 9,2 4,7 10,9 11,1 12,6↑

C33-C34

Men 22,1 23,0 18,8 14,1 12,1 ↓

Women 3,6 3,9 3,5 3,8 4,4 ↗

C50 Women 14,5 15,0 16,6 17,6 23,2 ↑

C61 Men 5,4 6,6 7,4 10,3 8,7 ↑

Non-melanom skin carcinomas formed in 1971 to 10%, in 2010 to 16%

Source: NCR SR *Preliminary data from the database hospitalized

MEN WOMEN

0

100

200

300

400

500

600

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

women 1971-1980 women 2001-2010

0

100

200

300

400

500

600

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

men 1971-1980 men 2001-2010

0

10

20

30

40

50

60

70

n /

per

10

0 0

00

, WSR

Year

men incidence men mortality

0

10

20

30

40

50

60

70

n /

per

10

0 0

00

, WSR

Yearwomen incidence women mortality

Development of standardized incidence and mortality

Age-standardized incidence

Source: Incidence – NCR SR / Mortality - National Health Information Center / Deaths - Statistical Office Slovakia / /

0

50

100

150

200

250

300

350

400

450

500

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

men 1971-1980 men 2001-2010

0

50

100

150

200

250

300

350

400

450

500

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

women 1971-1980 women 2001-2010

0

10

20

30

40

50

60

70

80

90

n /

per

10

0 0

00

, WSR

Year

men incidence men mortality

0

10

20

30

40

50

60

70

80

90

n /

per

10

0 0

00

, WSR

Year

women incidence women mortality

Development of standardized incidence and mortality

Age-standardized incidenceMEN WOMEN

Source: Incidence – NCR SR / Mortality - National Health Information Center / Deaths - Statistical Office Slovakia / /

MEN (C61) WOMEN ( C50)

0

100

200

300

400

500

600

700

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

women 1971-1980 women 2001-2010

0

10

20

30

40

50

60

70

80

n /

per

10

0 0

00

, WSR

Year

women incidence women mortality

0

100

200

300

400

500

600

700

25-34 35-44 45-54 55-64 65-74 75+

n /

per

10

0 0

00

, WSR

Ages

men 1971-1980 men 2001-2010

0

10

20

30

40

50

60

70

80

n /

per

10

0 0

00

, WSR

Yearmen incidence men mortality

Development of standardized incidence and mortality

Age-standardized incidence

Source: Incidence – NCR SR / Mortality - National Health Information Center / Deaths - Statistical Office Slovakia / /

18,8 18,1 18,6

25,1 27,2 26,4

17,221,6 26,5

23,120,9

26,215,9 12,2

2,3

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

2001 2006 2010

%

Year

Colorectal cancer

Unknown

IV.stage

III.stage

II.stage

I. stage8,0 8,2 7,56,9 5,5 5,6

26,1 23,3 27,2

33,6 43,0

56,2

25,4 20,03,5

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

2001 2006 2010

%

Year

Trachea and lung cancer

Unknown

IV.stage

III.stage

II.stage

I. stage

23,5 26,6 33,4

44,4 39,035,1

14,7 21,4 20,27,5

6,8 9,39,9 6,22,1

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

2001 2006 2010

%

Year

Breast cancer (women)

Unknown

IV.stage

III.stage

II.stage

I. stage11,6 8,3 6,8

25,6

54,0 59,615,8

15,117,7

23,2

13,514,423,8

9,01,5

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

2001 2006 2010

%

Year

Prostate cancer (men)

Unknown

IV.stage

III.stage

II.stage

I. stage

Source: NCR SR

34,4

75

27,3

40,5

14,58,8

42,8

64,6

34,3

50,3

32,9

48,6

19,3

14

52,4

74

0

10

20

30

40

50

60

70

80

1980-1984 2000-2004 1980-1984 2000-2004 1980-1984 2000-2004 1980-1984 2000-2004 1980-1984 2000-2004

C18 C19-C21 C33-C34 C61 C50

%

Men Women

Source: NCR SR: Cancer incidence in the Slovak Republic 2006 - Safaei Diba Ch., Hlava P., Pleško I.

Prostate BreastTrachea and lungRectosigmaColon

Goal 8 – Prevalence decrease of chronic diseases by 2020:

„Tumor mortality“ of any localization below 65 years of age has to be decreased minimum by 15% in average, lungs by 25%.

2015

2015

109,2WRS*

149,0 ERS*

↓ 30%

Men

56,5WRS*

74,9ERS*

↓14,7%

Women

80,4WRS*

108,9ERS*

↓ 24%

Total

15,6WRS*

22,0ERS*

↓ 48,5%

↓ 53,0%

Men

5,1WRS*

7,8ERS*

↑ 15,6%

↑ 8,3 %

Women

10,1WRS*

14,6ERS*

↓ 37,8%

↓ 43,0%

Total

2015/2000

2015/2000

Trachea and Lung cancer( C33-C34)

Overall cancer (C00-D09) in Slovakia

* Standardized according WHO ( WRS – World standard, ERS- European standard)

190,1214,7 223,4 223,9 229,4

248,5 254,6 261,1 274,4 278,9 281,9 300,4 307,8

0

50

100

150

200

250

300

350

400

450

Ukraine Latvia Austria Croatia Estonia Malta Sweden Slovakia Slovenia Norway Finland Denmark CzechRepublic

WOMEN

260,6301,8 308,1 316,8 317,7 321,7 338,6 340,6 345,5 354,6

377,0 378,7420,1

0

50

100

150

200

250

300

350

400

450

Ukraine Sweden Malta Latvia Austria Croatia Denmark Estonia Norway Finland Slovenia Slovakia CzechRepublic

MEN

n /

per

10

0 0

00

, W

SR

Source: IARC Cancer Incidence in Five Continents Vol.IX, / data for Slovakia – NCR SR, Safaei Diba and company

19,2 19,4 19,9 20,9 21,6 21,9 22,8 24,3 25,127,8 28,5 30,5

34,2

0

10

20

30

40

50

60

Ukraine Finland Latvia Malta Estonia Austria Sweden Croatia Slovenia Slovakia CzechRepublic

Denmark Norway

WOMEN

27,1 28,8 29,6 30,8 32 33,438,6

41,9 42,4 44,1 45,8

56,4 57

0

10

20

30

40

50

60

Finland Ukraine Latvia Sweden Malta Estonia Austria Denmark Norway Croatia Slovenia Slovakia CzechRepublic

MEN

n /

per

10

0 0

00

, W

SR

Source: IARC Cancer Incidence in Five Continents Vol.IX, / data for Slovakia – NCR SR, Safaei Diba and company

20,7 20,7

34,4 34,5 36,740,5

45

55,8 56,2 57,5 58,763,4 65,1

0

10

20

30

40

50

60

70

Sweden Ukraine Finland Malta Norway Austria Denmark Estonia Slovakia Slovenia CzechRepublic

Latvia Croatia

MEN

6,4 6,7 8,8 8,9 10,5 10,814 15,2 15,7 16,5 17,2

23,3

35,2

0

10

20

30

40

50

60

70

Ukraine Malta Latvia Estonia Slovakia Finland Croatia Slovenia CzechRepublic

Austria Sweden Norway Denmark

WOMEN

n /

per

10

0 0

00

, W

SR

Source: IARC Cancer Incidence in Five Continents Vol.IX, / data for Slovakia – NCR SR, Safaei Diba and company

18,1

38,7 39,5 42,752 54,8 56,5

69 69,5

83,1

98,5 102,2107,6

0

20

40

60

80

100

120

Ukraine Slovakia Croatia Malta Latvia Slovenia CzechRepublic

Denmark Estonia Austria Norway Finland Sweden

PROSTATA CANCER (C61) - MEN

39,948,4 48,9 51,7

59,4 63,6 64,6 66,972,5 75,9

81,1 83,2 86,1

0

20

40

60

80

100

120

Ukraine Latvia Estonia Slovakia Croatia Slovenia CzechRepublic

Austria Malta Norway Sweden Finland Denmark

BREAST CANCER (C50) - WOMENn /

per

10

0 0

00

, W

SR

Source: IARC Cancer Incidence in Five Continents Vol.IX, / data for Slovakia – NCR SR, Safaei Diba and company

NCR represents fundamental global source of clinico-epidemiological data of malignant tumors prevalence in time and space (regional differences) by:• age, sex, • tumor localization, • cytological/ histo-patological diagnostics • treatments

Data analysis & interpretation should act as basis for effective state health policy in the field with principle goals:• improve primary prevention of known risk factors/ optimize life style,• increase early disease identification / apply respective treatment = successful

prognosis/ health expectancy.

In recent years problems with data collection incurred by reporting units has had direct negative impact on accuracy of data processing. For the first time since it’s establishment NCR Slovakia will not have stated data in publication „Cancer Incidence in Five Continents Vol.X.“ (IARC) due to lack of complexity of primary data from reporting units for years of 2011-2013. However there has been ongoing discussions between Health department SR and it’s chief experts of Ministry of Health about new ways of data collection which would strenghten e-reporting to NCR Slovakia.

Health 21. for European region, Goal 14All government departments should recognize and accept their responsibility for population’s health condition by 2020 (assessment of department’s impact on health).

Health 21... Goal 8- Prevalence decrease of chronic diseasesPublic health depends on interdepartmental approach. Principle target is to have a complex approach for the most important risk factors in human behavior and only that creates environment where multi-departmental initiatives are aligned government directions and particular efforts of each single being