commissioning of nirs gantry - agenda (indico) · naoya saotome 1. himac nirs contents 2017/2/23...

Commissioning of NIRS Gantryand KCC i-RockNational Institute of Radiological Sciences

Naoya Saotome

1

HIMAC

NIRS

Contents

2017/2/23 Naoya Saotome(NIRS) 2

Introduction

KCC i-ROCK

NIRS Gantry

History and collaboration

Commissioning of commercial scanning system

Commissioning of NIRS’s Gantry with superconducting magnet

HIMAC

NIRS

Contents


Introduction

KCC i-ROCK

NIRS Gantry




HIMAC

NIRS

OUR EVOLUTION


5.20m

Iso-center

SCN01

SM-XSM-Y

SCN02RSF

Main monitor PRN

PH1

2008Experimental port for scanning

2011New treatment roomswith scanning

2015Commercial machinewith scanning

2017SuperconductingGantry for carbon ion

By courtesy of Toshiba

HIMAC

NIRS

2013 2014 2015 2016 2017 2018 2019 2020

OUR RECENT PROGRESS

5

Building construction start(12/12)

KCC: Kanagawa Cancer Center NIRS: National Institute of Radiological Sciences

Installation start (14/5)

Accelerate 430MeV/u (15/1)

Multiple-energy operation and scanning irradiation(15/2)

Treatment start (15/12)

Treatment start(15/2)

Beam commissioning start (16/1)

Installation start(15/1)

Beam commissioning start(10/13)

Treatment start (17/4,plan)

Energy scanning

Gantry

HIMAC

NIRS

OUR COLLABORATION

Naoya Saotome(NIRS) 6

DESIGN

DEVELOPENTCOMMISSIONING

USING

(TREATMENT)

National Institute of Radiological Sciences

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

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74e−0

7

0 50 100 150 200 250 300 350

0e+0

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7

0 50 100 150 200 250 300 350

0e+0

01e−0

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7

0 50 100 150 200 250 300 350

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7

0 50 100 150 200 250 300 350

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7

0 50 100 150 200 250 300 350

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7

0 50 100 150 200 250 300 350

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7

0 50 100 150 200 250 300 350

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01e−0

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7

0 50 100 150 200 250 300 350

0e+0

01e−0

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7

0 50 100 150 200 250 300 350

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7

20160808_GRC_20160809052036LGRC_IDD_000_PM1m

Amou

nt o

f ion

izatio

n [C

]

Moter value [mm]

● 20160809052036LGRC_IDD_000_PM1m20160809054241LGRC_IDD_008_PM1m20160809055742LGRC_IDD_016_PM1m20160809061159LGRC_IDD_024_PM1m20160809062717LGRC_IDD_032_PM1m20160809064231LGRC_IDD_040_PM1m

Rad symbol means 'Over Flow'

drawn by RF63_IDD_forGComi_20160812_Overflow

(integral)

COLLABORATION129

9.

9.1.

9m

9.1-1 1.3m

9.1-1

SCN SCMX SCMY

DSN_M DSN_S DSN_P

RGF RSF

9.1.1.

10 (vx, vy)=(100, 50) mm/ms

9.1-2 9.1-1

FRP

IGBT FET

E

SCMXSCMY SCN

DSN_MDSN_S

DSN_P

RGFRSF

IC NST FST

2017/2/23

HIMAC

NIRS

Contents


Introduction

KCC i-ROCK

NIRS Gantry




HIMAC

NIRS

Specification of KCC

2017/2/23

item specification

Ion C6+

Energy 140-430MeV/u

Max. field 220 x 220 mm2

Max. dose rate 2 Gy/L/min

Beam intensity 1.2x109 pps

Irradiation type 3D Scanning

Treatment roomsHorizontal: 2 rooms

Horizontal and Vertical: 2

rooms

Vender Toshiba

Combination of a compact dissemination treatment system

and pencil beam 3D scanning technique designed by NIRS

Moving target treatment is available with respiratory-gated

and rescanning technique


HIMAC

NIRS

Building Construction


HIMAC

NIRS

2013 2014 2015 2016 2017 2018 2019 2020

OUR RECENT PROGRESS

10

Building construction start(12/12)

KCC: Kanagawa Cancer Center NIRS: National Institute of Radiological Sciences

Installation start (14/5)

Accelerate 430MeV/u (15/1)

Multiple-energy operation and scanning irradiation(15/2)

Treatment start (15/12)

HIMAC

NIRS

DARUMA CEREMONY


HIMAC

NIRS

Commissioning of the irradiation system


NON-scanned beam testBeam intensity

Beam position

Beam size

Beam on/off response

Scanned beam testScanned beam position

Field uniformity

Complex field

Dose monitor performance

Position monitor performance

Beam data collection for TPSBeam size

Beam divergent

Integral depth-dose

Dose monitor unit

Interlock check

Information transfer check

Coordinate check

End-to-End test

Training for staff

Beam matching

Overall verification

HIMAC

NIRS

Beam intensity


Extended FT + Multiple Energy

Operation

Extended FT + Intensity Modulation

Operation

HIMAC

NIRS

Beam size and position


150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]

●

●●

●

●

●

●

●

●

●

●

150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 4501.

01.

52.

02.

53.

03.

54.

0

Energy [MeV/n]

Beam

Size

[mm

]● 1HC

2HC2VC

430MeV

140MeV

Beam shape was adjusted as round shape

Beam size was adjusted within 10 percent from designed

Beam size for each treatment port were matched

Screen monitor for spot

HIMAC

NIRS

Beam size and position

2017/2/23 15

Beam position (2VC) Beam size (2VC)

. +0+.-

. +0+.-

+1

+1

Beam position stability was within +/-0.5mm

Beam size stability was within +/-0.5mm from design

Naoya Saotome(NIRS)

HIMAC

NIRS

Integral depth dose


Depth [mm]

Dose

of i

nteg

ral e

lect

rode

[C]

●●

●●

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●

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150 155 160

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1.0

20160407_rangecheck_1HC_RID06

●

BeamData_KCC20151130_inaniwa2 − RID06_PMMA20160407_rangecheck 1HC_RID06 offset= 9.1 ,scallcor= 120160407_rangecheck 2HC_RID06 offset= 9.1 ,scallcor= 120160407_rangecheck 2VC_RID06 offset= 6.3 ,scallcor= 1

0 50 100 150 200 250 300 350

020

4060

8010

012

0

Depth in water[mm]

Inte

gral

dep

th d

ose

[A.U

.]

020

4060

8010

012

0

Concentric Ionization chamber

IDD for 11 energy beams

3D Water phantom

Beam energy/range was adjusted

Residual range for each treatment

port were matched

Lateral distribution was used for TPS

beam modelling

HIMAC

NIRS

Scanned beam position


ü 240x240mm2 field ü 20 mm pitch

Screen monitor for field

Scanned beam position for every beam energy was checked

Beam shape was adjusted as round shape at any position

The precision of the scanned beam position was verified

within 0.5 mm.

430MeV/u

380MeV/u

+/-0.5mm

+/-0.5mm

+/-0.5mm

+/-0.5mm

ü 240x240mm2 field ü 20 mm pitch

HIMAC

NIRS

Field uniformity

2017/2/23 Naoya Saotome(NIRS)


Field uniformity for every beam energy was checked

The flatness of the uniform field was verified within +-1.5 %

290MeV/u

± 1.5%

± 1.5%

ü 150x150mm2 field ü 2mm pitch

18

HIMAC

NIRS

Complex field


Position monitor system

Beam intensity, dose, and beam position were modulated

Complex field for every beam energy was checked

The dose distribution was compared with plan and confirmed

Flanz et al., PTCOG2009

HIMAC

NIRS

3D dose distribution


Rectangle shape irradiation fields were planned

Dose distribution on the depth and lateral direction were

compared with planned dose distribution

Treatment planning

3D Water phantom

Depth dose distribution Lateral dose distribution

HIMAC

NIRS

Beam matching


Lateral position [mm]

●●●●●●●

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planmeas

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Dose

[Gy]

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planmeas

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[Gy]

−100 −50 0 50 100

../data/1HC_20160222/la_HN005bH.csv


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planmeas

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Dose

[Gy]

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planmeas

0.4

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Dose

[Gy]

−100 −50 0 50 100

../data/2HC_20160217/la_HN005bH.csv


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planmeas

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2.0

Dose

[Gy]

−100 −50 0 50 100

Lateral position [mm]●

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●

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●●●●●●●●

●

●Lateral position [mm]

●

planmeas

1.8

1.9

2.0

2.1

2.2

Dose

[Gy]

−100 −50 0 50 100

../data/2HC_20160217/la_PR003_111a.csv


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planmeas

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1.0

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2.0

Dose

[Gy]

−100 −50 0 50 100


●

●

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●

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●


●

planmeas

1.8

1.9

2.0

2.1

2.2

Dose

[Gy]

−100 −50 0 50 100

../data/1HC_20160222/la_PR003_111a.csv

Depth [mm]

Dose

of i

nteg

ral e

lect

rode

[C]

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150 155 160

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0.2

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0.8

1.0

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0.2

0.4

0.6

0.8

1.0

150 155 160

0.0

0.2

0.4

0.6

0.8

1.0

0.0

0.2

0.4

0.6

0.8

1.0

20160407_rangecheck_1HC_RID06

●

BeamData_KCC20151130_inaniwa2 − RID06_PMMA20160407_rangecheck 1HC_RID06 offset= 9.1 ,scallcor= 120160407_rangecheck 2HC_RID06 offset= 9.1 ,scallcor= 120160407_rangecheck 2VC_RID06 offset= 6.3 ,scallcor= 1

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

●

●●

●

●

●

●

●

●

●

●

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

150 250 350 450

1.0

1.5

2.0

2.5

3.0

3.5

4.0

Energy [MeV/n]

Beam

Size

[mm

]

● 1HC2HC2VC

430MeV

140MeV

Sample patient field for Prostate and H&N were planned

The plan were deliver and measured at each treatment rooms

Beam size and range matching brought dose distribution

matching

Room 1

Room 2

Beam size matching

Range matching

H&NProstate

HIMAC

NIRS

2Gy/L/min


−100 −50 0 50 100

020

4060

80100

Relati

ve Do

se [A.

U.]

● ● ● ● ● ●●

●

●● ●

● ● ● ● ● ● ●

●

●

● ● ● ● ● ● ●

−100 −50 0 50 100

020

4060

80100

−100 −50 0 50 100

020

4060

80100

−100 −50 0 50 100

020

4060

80100

● −10mm10mm10mm

Lateral Position [mm]

97.5%

102.5%

2Gy of physical dose to 10x10x10cm3 cubic target was planned

The dose homogeneity was better than 2.5%

Treatment planning

Lateral dose distribution

57 sec

+/-2.5%

HIMAC

NIRS

DARUMA CELEMONY

2017/2/23 23

HIMAC

NIRS

Contents


Introduction

KCC i-ROCK

NIRS Gantry




HIMAC

NIRS

ADVANTAGES OF GANTRY


HIMAC

NIRS

Specification of NIRS’s Gantry

2017/2/23

item specification

Ion C6+

Energy 48-430MeV/u

Max. field 200 x 200 mm2

Irradiation type 3D Scanning

Rotating angle +/- 180 degree

Magnet type Superconducting magnet

Beam orbit radius 5.45 m

Length 13 m

Weight 300 ton

Vender Toshiba

Function combined superconducting magnets were

employed

Moving target treatment is available with respiratory-gated

and rescanning technique


HIMAC

NIRS

Construction and installation


HIMAC

NIRS

installation


Gantry room Treatment room

HIMAC

NIRS

Commissioning of the Gantry


NON-scanned beam testBeam intensity

Beam position

Beam size

Beam on/off response

Scanned beam testScanned beam position

Field uniformity

Complex field

Dose monitor performance

Position monitor performance

Beam data collection for TPSBeam size

Beam divergent

Integral depth-dose

Dose monitor unit

Interlock check

Information transfer check

Coordinate check

End-to-End test

Training for staff

Beam matching

Overall verification

Gantry angle dependence checkBeam position

Beam size

Dose output

Scanned beam position

HIMAC

NIRS

Angle dependence of the beam size

• Angular dependence of a beam size and shape at the

isocenter (E=430 MeV/u)

180 deg 135 deg 90 deg 67.5 deg 45 deg

22.5 deg 0 deg -45deg -90deg -135deg


HIMAC

NIRS

Angle dependence of the beam size


50 100 150 200 250 300 350 400 4500

1

2

3

4

Degree 0 45 90 135 180 225 270 315

Late

ral B

eam

Spr

ead

(1) [

mm

]

Energy [MeV/u]

Screen monitor for spot

Measurement sequence

The accuracy of the beam size and beam position for every

gantry angle were checked

The measurement was performed with sequence

(15min for 200Energy)

Angle dependent of the beam size is less than 10%

HIMAC

NIRS

0

0.5

1

1.5

2

2.5

3

0 50 100 150 200 250 300 350 400 450

1σ b

ea

m s

ize a

t Iso

[mm

]

E [MeV/u]

σx

σy

Beam size

• Beam tuning was made for various beam energies• E=430~55.6 MeV/u

430 MeV/u 387 MeV/u 292 MeV/u

238 MeV/u 174 MeV/u 55.6 MeV/u


HIMAC

NIRS

Angle dependence of the beam position


Digital starshout device

3D Water phantom

The accuracy of the isocenter position and gantry angles are

checked using digital starshout device

Beam position accuracy for each gantry angle was confirmed within

+/- 0.5mm.

HIMAC

NIRS

Integral Dose Distribution


0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

●●●●●●●●● ● ● ● ● ● ●●

●●●●

●●●●●●●

●

●●

●

●●●●

●

●

●

●

●

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0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0 50 100 150 200 250 300 350

0e+0

01e−0

72e−0

73e−0

74e−0

7

0e+0

01e−0

72e−0

73e−0

74e−0

7

20160808_GRC_20160809052036LGRC_IDD_000_PM1m

Amou

nt o

f ion

izatio

n [C

]

Moter value [mm]

● 20160809052036LGRC_IDD_000_PM1m20160809054241LGRC_IDD_008_PM1m20160809055742LGRC_IDD_016_PM1m20160809061159LGRC_IDD_024_PM1m20160809062717LGRC_IDD_032_PM1m20160809064231LGRC_IDD_040_PM1m



(integral)

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

●●●●●●●●● ●

●●●●●

●

●

●

●

●

●

●

●

●●●

●

●

●

●

●

●●●●●●●●● ● ● ● ● ●

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0 50 100 150 200 250 300 350

0e+0

02e−0

74e−0

76e−0

7

0e+0

02e−0

74e−0

76e−0

7

20160808_GRC_20160810030226LGRC_IDD_144_AL1cm

Amou

nt o

f ion

izatio

n [C

]

Moter value [mm]

● 20160810030226LGRC_IDD_144_AL1cm20160810033213LGRC_IDD_152_AL1cm20160810034759LGRC_IDD_160_AL1cm20160810040802LGRC_IDD_168_AL1cm20160810042155LGRC_IDD_176_AL1cm20160810043523LGRC_IDD_184_AL1cm



(integral)

Concentric Ionization chamber

3D Water phantom

Beam energy/range was adjusted

Lateral distribution was used for TPS beam modelling

Low energy High energy

HIMAC

NIRS

Dose output


Dose output for every gantry angle was checked using

famer type ionization chamber

Angle dependence of the dose output was less than 0.5%

0 60 120 180 240 300-1.00

-0.75

-0.50

-0.25

0.00

0.25

0.50

0.75

1.00

430 MeV/u 290 MeV/u 89 MeV/u

Dos

e [%

]

Ganrty Angle [degree]

HIMAC

NIRS

Scanned Beam Position


-1.5

-1

-0.5

0

0.5

1

1.5

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Scanned beam position for every beam

energy and gantry angle was checked

Beam shape was adjusted as round

shape at any position and any gantry angle

The precision of the scanned beam

position after the distortion correction was

verified within 0.5 mm.

(-)Distortion correction

(+)Distortion correction

HIMAC

NIRS


2017/2/23 38Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]

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plans1_plans2_plans3_plans4_plans5_plan

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Dose

[Gy]

0 50 100 150 200 250 300

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02

4

Range in water [mm]0 50 100 150 200 250 300

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diff

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ce [%

]

../result/NIRSG_20170216/dd_AL1c_d1rec30todd_AL1c_d5rec30_g02.pdf

Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]

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Range in water [mm]

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plans1_plans2_plans3_plans4_plans5_plan

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Dose

[Gy]

0 50 100 150 200 250 300

Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]Range in water [mm]

−4−2

02

4

Range in water [mm]0 50 100 150 200 250 300

Dose

diff

eren

ce [%

]

../result/NIRSG_20170216/dd_AL1c_d1rec90todd_AL1c_d5rec90_g02.pdf

Lateral position [mm]Lateral position [mm]Lateral position [mm]Lateral position [mm]Lateral position [mm]Lateral position [mm]

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plans1s2s3s4s5

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Dose

[Gy]

−100 −50 0 50 100


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plans1s2s3s4s50.

961.

001.

04

Dose

[Gy]

−100 −50 0 50 100

../result/NIRSG_20170216/la_AL1c_d1rec30tola_AL1c_d1rec90_g02.pdf


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../result/NIRSG_20170216/la_AL1c_d2rec30tola_AL1c_d2rec90_g02.pdf




3D Water phantom

Depth dose distribution Lateral dose distribution

Pin-point chamber array

Naoya Saotome(NIRS)

HIMAC

NIRS


2017/2/23 39




3D Water phantom

Lateral dose distribution

Pin-point chamber array


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../data/NIRSG_20170216/la_AL1c_926108_1_HN_−11175mm.csv


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../data/NIRSG_20170216/la_AL1c_920070_2_Pro_d3mm_0.csv


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../data/NIRSG_20170216/la_AL1c_924016_1_Pro_d29mm_0.csv

Naoya Saotome(NIRS)

HIMAC

NIRS

SUMMARY


Fast scanning system dedicated for moving target was

succeeded at NIRS

Commercial system which is combination of a compact

dissemination treatment system and pencil beam 3D

scanning technique was constructed at KCC

Treatment using superconducting rotating-gantry will be

started in near future

commissioning of nirs gantry - agenda (indico) · naoya saotome 1. himac nirs contents 2017/2/23...

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