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clinical uses of enzymes, diagnostic importance of enzymes

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Enzymes in clinical use

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Page 1: Clinical uses of enzymes, diagnostic importance of enzymes

Enzymes in clinical use

Page 2: Clinical uses of enzymes, diagnostic importance of enzymes

DIAGNOSTIC VALUE OF SERUM ENZYMES

Page 3: Clinical uses of enzymes, diagnostic importance of enzymes

CARDIAC BIOMARKERS

CK-MB AST LDH

Page 4: Clinical uses of enzymes, diagnostic importance of enzymes

ENZYME PROFILE IN LIVER DISEASE

ALTALP

obstructive

γGThepatobi

liary

Page 5: Clinical uses of enzymes, diagnostic importance of enzymes

ALT Alanine aminotransaminase ↑ in acute liver damage

ALP Alkaline phosphatase Bone & liver↑in rickets, hyperparathyroidism, Paget disease, obstructive

jaundice, osteoblastic sarcoma.

γGTGamma glutamyl transpeptidase↑ in hepatobiliary obstruction, alcohol induced liver disease

Page 6: Clinical uses of enzymes, diagnostic importance of enzymes

ALP ↑ in bone disease ACID PHOSPHATASE ↑ in prostatic carcinoma with

metastasis CREATINE KINASE(MM) ↑ in muscle disease AMYLASE ↑ in parotitis, acute pancreatitis

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