Clinical Trials for Obesity and its co-morbidities

Jenny Brown

Clinical Nurse Specialist

NHS Grampian

Consequences of obesity

Respiratory diseaseHeart disease

Gall bladder disease

Hormonal abnormalities

Hyperuricaemiaand gout

Stroke

Cardiovascular risk factors

Diabetes

OsteoarthritisCancer

Depression

Ethics

• Staff expertise

• Coercion

• Clinician/researcher dilemma

Recruitment

• Access to participants

• ‘Magic Pill’ or ‘not a problem’

• Reluctance to consent

Retention

• Approach to subjects

• Flexibility

Practicalities

• Transportation

• Facilities

Group Discussion

Share your knowledge and experience todiscuss the following questions.

1. How would you prepare staff for working on obesity trials?

2. What practical aspects need to be considered when undertaking research for obesity?