childhood vaccinations: questions all parents should ask - bcc vaccine talk 2

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Childhood Vaccinations: Questions All Parents Should Ask. I’d like to thank you for coming this evening, afternoon etc. One of the most important health decisions facing parents today is whether or not to have their child vaccinated. This decision should be based on facts rather than coercion or pressure. We therefore ask you to keep an open mind to the information we’re going to present.

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Page 1: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

VaccinationsVaccinations

Page 2: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2
Page 3: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

The most recent National Immunization The most recent National Immunization Coverage Survey of households by HealthCoverage Survey of households by Health

Canada, performed in 2002, found that only Canada, performed in 2002, found that only 56.7% of 2 year old56.7% of 2 year old children had received children had received all of the recommended DPTP/Hib and all of the recommended DPTP/Hib and MMRMMR immunizations. - immunizations. - Volume Matters: Physician Practice Characteristics Volume Matters: Physician Practice Characteristics

and Immunization Coverage Among Young Children Insured Through a Universal Health Planand Immunization Coverage Among Young Children Insured Through a Universal Health PlanAstrid Guttmann, Doug Manuel, Paul T. Dick, Teresa To, Kelvin Lam, and Therese A. StukelAstrid Guttmann, Doug Manuel, Paul T. Dick, Teresa To, Kelvin Lam, and Therese A. StukelPediatrics 2006; 117: 595-602Pediatrics 2006; 117: 595-602. .

Page 4: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

More parents are rejecting More parents are rejecting vaccinations for their childrenvaccinations for their children

They consider the vaccines more They consider the vaccines more dangerous than the diseasedangerous than the disease

They prefer natural rather than artificial They prefer natural rather than artificial immunityimmunity

They have a vaccine-injured child (a They have a vaccine-injured child (a growing number)growing number)

They have religious or philosophical They have religious or philosophical objections to vaccinationobjections to vaccination

Page 5: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Question: Are vaccinated children Question: Are vaccinated children healthier than non-vaccinated healthier than non-vaccinated

children?children?

Page 6: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

There is no proof vaccinated There is no proof vaccinated children are healthierchildren are healthier

No major study has compared No major study has compared vaccinated and nonvaccinated vaccinated and nonvaccinated children to see which is healthier.children to see which is healthier.

Page 7: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Immunized children: 23.1% had asthma, 30% had other allergic illnesses.Non-immunized children: 0% had asthma or other allergic illness.

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Page 9: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

11% of vaccinated children were 11% of vaccinated children were diagnosed with asthma vs 2% of diagnosed with asthma vs 2% of unvaccinated children -unvaccinated children - Odent M, Odent M, Culpin E, Kimmel T, Pertussis vaccination Culpin E, Kimmel T, Pertussis vaccination and asthma : is there a link ? JAMA 1994 ; and asthma : is there a link ? JAMA 1994 ; 272 : 592-3 272 : 592-3

Page 10: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

DPPT or MMR and DPPT or MMR and allergies/asthma allergies/asthma

Children vaccinated with Children vaccinated with DPPT (or MMR) had DPPT (or MMR) had 14 times more asthma and and 9.4 times more eczema than non- than non-vaccinated children. vaccinated children. McKeever TM, Lewis SA, Smith C. Does vaccination increase the risk of developing allergic disease?: A birth cohort study. Winter Abstract supplement to Thorax, 2002; 57: Supplement III

Page 11: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

•Measles vaccination in childhood was Measles vaccination in childhood was related to the following diseases in adult related to the following diseases in adult life: autoimmune diseases…skin life: autoimmune diseases…skin diseases, degenerative diseases of bone diseases, degenerative diseases of bone and cartilage and certain tumors. and cartilage and certain tumors. Renne T. Renne T. Measles virus infection without rash leads to disease in adult life. Measles virus infection without rash leads to disease in adult life. LancetLancet 5 January 1985. 5 January 1985.

Page 12: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

TH1 TH2TH1 TH2

Page 13: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

IngredientsIngredientsaluminum hydroxide aluminum hydroxide aluminum phosphatealuminum phosphateammonium sulfateammonium sulfateamphotericin Bamphotericin Banimal tissues: pig blood, horse animal tissues: pig blood, horse blood, rabbit brain, blood, rabbit brain, dog kidney, monkey kidney, dog kidney, monkey kidney, chick embryo, chicken egg, chick embryo, chicken egg, duck eggduck eggcalf (bovine) serumcalf (bovine) serumbetapropiolactonebetapropiolactonefetal bovine serumfetal bovine serumformaldehydeformaldehydeformalin formalin gelatin gelatin glycerolglycerolhuman diploid cells (originating human diploid cells (originating from human aborted fetal from human aborted fetal tissue)tissue)hydrolized gelatin hydrolized gelatin

hydrolized gelatin monosodium glutamate (MSG)neomycinneomycin sulfatephenol red indicatorphenoxyethanol (antifreeze)potassium diphosphatepotassium monophosphatepolymyxin Bpolysorbate 20polysorbate 80porcine (pig) pancreatic hydrolysate of caseinresidual MRC5 proteinssorbitol sucrosethimerosal (mercury)tri(n)butylphosphate,VERO cells, a continuous line of monkey kidney cellswashed sheep red blood cells

Page 14: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

MercuryMercury

One of the most poisonous One of the most poisonous substances known to exist in nature.substances known to exist in nature.

Children have received up to 125 Children have received up to 125 times the safe limit of mercury set by times the safe limit of mercury set by the EPA (autism skyrocketed).the EPA (autism skyrocketed).

Symptoms of mercury toxicity Symptoms of mercury toxicity resemble those of autism.resemble those of autism.

Mercury is still in use (as of 2003.)Mercury is still in use (as of 2003.)

Page 15: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2
Page 16: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

• One in 10,000 births were autistic in 1970sOne in 10,000 births were autistic in 1970s

• One in 500 in 1980sOne in 500 in 1980s

• One in 100 in 1990sOne in 100 in 1990s

• One in 86 in 2002 (UK study).One in 86 in 2002 (UK study).

• One in 165 today - One in 165 today - PediatricsPediatrics, July 2006 , July 2006

• In an investigation of unvaccinated Amish population, it was In an investigation of unvaccinated Amish population, it was expected that 200 children would be Autistic (based on the expected that 200 children would be Autistic (based on the 1/165 ratio) – only 3 were found, and all had been vaccinated! 1/165 ratio) – only 3 were found, and all had been vaccinated! (Washington Post, April 18(Washington Post, April 18thth 2005) 2005)

• If improved detection/diagnosis were the reason for If improved detection/diagnosis were the reason for increased Autism rates, where are all the Autistic adults?increased Autism rates, where are all the Autistic adults?

Question: Do vaccines cause Question: Do vaccines cause autism?autism?

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Page 18: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Formalin/AluminumFormalin/Aluminum

Formalin is a dilute formaldehyde solution. Formalin is a dilute formaldehyde solution. Nearly 50 studies have shown a link Nearly 50 studies have shown a link between formaldehyde exposure and between formaldehyde exposure and leukemia and brain, colon and lymphatic leukemia and brain, colon and lymphatic cancer.cancer.

Aluminum is a neurotoxin that crosses the Aluminum is a neurotoxin that crosses the brain/blood barrier. brain/blood barrier. Neustaedter R. Neustaedter R. The Vaccine Guide,The Vaccine Guide, Berkley, CA: North Atlantic Books. 1996.Berkley, CA: North Atlantic Books. 1996.

Page 19: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

AluminumAluminum ““After 20 weeks studying the mice, the team found statistically After 20 weeks studying the mice, the team found statistically

significant increases in anxiety (38 percent); memory deficits significant increases in anxiety (38 percent); memory deficits (41 times the errors as in the sample group); and an allergic (41 times the errors as in the sample group); and an allergic skin reaction (20 percent). Tissue samples after the mice were skin reaction (20 percent). Tissue samples after the mice were "sacrificed" showed neurological cells were dying. Inside the "sacrificed" showed neurological cells were dying. Inside the mice's brains, in a part that controls movement, 35 percent of mice's brains, in a part that controls movement, 35 percent of the cells were destroying themselves” – Study performed at the cells were destroying themselves” – Study performed at UBC, 2006UBC, 2006

Research by Dr. Hugh Fudenberg, M.D., the world's leading Research by Dr. Hugh Fudenberg, M.D., the world's leading immunogeneticist and 13th most quoted biologist of our times immunogeneticist and 13th most quoted biologist of our times (author of nearly 850 papers in peer reviewed journals), (author of nearly 850 papers in peer reviewed journals), shows that individuals who had five consecutive flu shots shows that individuals who had five consecutive flu shots have a ten times higher chance (1000%) of getting have a ten times higher chance (1000%) of getting Alzheimer's disease than if they had only one or two or no Alzheimer's disease than if they had only one or two or no shots.shots.

Page 20: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

2 questions2 questions

1)1)Are vaccines effective Are vaccines effective at preventing at preventing disease?disease?

2)2)Are vaccines responsible for eradicating Are vaccines responsible for eradicating infectious diseases in 20infectious diseases in 20thth century? century?

Page 21: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Question: are vaccinations Question: are vaccinations “effective?”“effective?”

What does effective mean?What does effective mean?CDC: “Effective” means antibodies CDC: “Effective” means antibodies

are produced, not clinical are produced, not clinical effectiveness (i.e. no disease).effectiveness (i.e. no disease).

However, there is often no correlation However, there is often no correlation between antibodies and resistance to between antibodies and resistance to disease. disease.

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“[Pertussis] infections are common in an immunized population…more prevalent than previously documented.” 98% were vaccinated in this population. He Q, Vijanen MK, Arvilommi H et al. Whooping cough caused by Bordetella pertussi and Bordetella parapertussis in an immunized population. Journal of the American Medical Association. 1998;280:635-637.

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Outbreaks have occurred in Outbreaks have occurred in 100% vaccinated populations.100% vaccinated populations. Morbidity and Mortality Weekly Report.Morbidity and Mortality Weekly Report. US Govt. 12/29/89/38(S- US Govt. 12/29/89/38(S-9):1-18.9):1-18.

““80% cases of measles are 80% cases of measles are contracted in vaccinated contracted in vaccinated people.” people.” Morbidity and Mortality Weekly Report.Morbidity and Mortality Weekly Report. US Govt. US Govt.

6/6/86/35(22):366-70.6/6/86/35(22):366-70.

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More pertussis since vaccinationMore pertussis since vaccination

With mandatory vaccination and 5 doses of With mandatory vaccination and 5 doses of DPT vaccine, pertussis occurs at a far DPT vaccine, pertussis occurs at a far higher rate now than before the higher rate now than before the introduction of the vaccine. “There is introduction of the vaccine. “There is substantial underreporting of pertussis…substantial underreporting of pertussis…including hospitalizations.” including hospitalizations.” Sutter RW and Cochi SL. Sutter RW and Cochi SL. Pertussis hospitalizations and mortality in the United States, 1985-Pertussis hospitalizations and mortality in the United States, 1985-1988. 1988. JAMA. 1992;JAMA. 1992;267(3):386-390. 267(3):386-390.

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Whooping cough deaths increase Whooping cough deaths increase despite all the vaccinationsdespite all the vaccinations

““The number of infants dying from whooping The number of infants dying from whooping cough is rising despite record high cough is rising despite record high vaccination levels. vaccination levels. All the deaths in 2000 All the deaths in 2000 occurred among infants under the age of 4 occurred among infants under the age of 4 months.”months.”

““Since the early 1980s, reported pertussis Since the early 1980s, reported pertussis incidence has incidence has increasedincreased cyclically with cyclically with peaks occurring every 3-4 years.”peaks occurring every 3-4 years.”

Morbidity and Mortality Weekly Report. Feb 1, 2002;51:73-76. Morbidity and Mortality Weekly Report. Feb 1, 2002;51:73-76. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5104a1.htmhttp://www.cdc.gov/mmwr/preview/mmwrhtml/mm5104a1.htm

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Vaccines interfere with Vaccines interfere with transplacental immunity transplacental immunity

Girls who are vaccinated have Girls who are vaccinated have less protection to pass on to less protection to pass on to their unborn child. their unborn child. (a)(a) More More measles now occurs in measles now occurs in children less than 1 and adults children less than 1 and adults 25+25+ (b) (b) (a) Papania M, Baughman AL, Lee S, et al Increased (a) Papania M, Baughman AL, Lee S, et al Increased susceptibility to measles in infants in the United States. Pediatrics. susceptibility to measles in infants in the United States. Pediatrics. 1999;104(5):e59 National Immunization Program, Epidemiology 1999;104(5):e59 National Immunization Program, Epidemiology Program Office, Centers for Disease Control and Prevention, Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. (b) MMWR 1991;40:369-372 in Atlanta, Georgia 30333, USA. (b) MMWR 1991;40:369-372 in JAMA;JAMA;1991;265(24).1991;265(24).

Page 27: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Hib vaccineHib vaccine

Since the vaccine Hib meningitis has Since the vaccine Hib meningitis has declined but other types of meningitis declined but other types of meningitis have increased to levels higher than have increased to levels higher than before the Hib vaccine was used.before the Hib vaccine was used.

Replacement chapter for “immunization against infectious disease” Replacement chapter for “immunization against infectious disease” 1996: Chapter 23, Meningococcal. [British] Dept of Health. [Pub by 1996: Chapter 23, Meningococcal. [British] Dept of Health. [Pub by NHS Executive.) NHS Executive.) www./doh.gov.uk/meningitis-vaccine/chapter23.htmwww./doh.gov.uk/meningitis-vaccine/chapter23.htm

Beattie G. Beattie G. Vaccination: A Parent’s Dilemma.Vaccination: A Parent’s Dilemma. Australia: Bunya Australia: Bunya Books. 1997.Books. 1997.

Page 28: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Mumps Outbreak in Atlantic Mumps Outbreak in Atlantic CanadaCanada

““The Halifax outbreaks have occurred in The Halifax outbreaks have occurred in both a doubly vaccinatedboth a doubly vaccinated cohort of cohort of adolescents, and a singly vaccinated adolescents, and a singly vaccinated cohort of youngcohort of young adults. The nature of these adults. The nature of these outbreaks raises questions as tooutbreaks raises questions as to tthe he efficacy of the MMR vaccine in each of efficacy of the MMR vaccine in each of these cohorts.” - these cohorts.” - Two successive outbreaks of mumps in Nova Scotia Two successive outbreaks of mumps in Nova Scotia

among vaccinated adolescents and young adultsamong vaccinated adolescents and young adults Gaynor Watson-Creed, Andrea Saunders, Gaynor Watson-Creed, Andrea Saunders, Jeffrey Scott, Luis Lowe, Janice Pettipas, and Todd F. HatchetteJeffrey Scott, Luis Lowe, Janice Pettipas, and Todd F. Hatchette

Can. Med. Assoc. J. 2006; 175: 483-488.Can. Med. Assoc. J. 2006; 175: 483-488.

Page 29: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

TetanusTetanus

Associated with improper wound cleaning, Associated with improper wound cleaning, malnutrition and a weak immune system.malnutrition and a weak immune system.

Decreased 92% from mid-1850s to early Decreased 92% from mid-1850s to early 1900s (before vaccination).1900 -1999: 1900s (before vaccination).1900 -1999: 473 - 70 deaths. Most occur in those over 473 - 70 deaths. Most occur in those over 50 (95% of fatalities); 5% of tetanus 50 (95% of fatalities); 5% of tetanus occurs under age 20. Fatalities are rare occurs under age 20. Fatalities are rare among younger people.among younger people.

Page 30: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Chicken pox (varicella)Chicken pox (varicella)

A mild self-limiting disease that gives A mild self-limiting disease that gives permanent life long immunity if caught permanent life long immunity if caught as a child but is much more as a child but is much more dangerous in adults.dangerous in adults.

The chances of a child becoming The chances of a child becoming seriously ill and dying from chicken seriously ill and dying from chicken pox are about equal to winning the pox are about equal to winning the lottery.lottery.

Page 31: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

NNTNNT For varicella vaccination, For varicella vaccination, we estimatedwe estimated that 34 000 people that 34 000 people

would need to be vaccinated to prevent 1would need to be vaccinated to prevent 1 deathdeath (using mortality (using mortality rates reported by Brisson and Edmundsrates reported by Brisson and Edmunds2525 and assuming 100% and assuming 100% efficacy against the varicella-zoster virusefficacy against the varicella-zoster virus and no waning in and no waning in protection). protection). To prevent 1 meningococcal-relatedTo prevent 1 meningococcal-related death, we death, we estimated that about 21 000 people would need to beestimated that about 21 000 people would need to be

vaccinatedvaccinated (using mortality data reported by De Wals and (using mortality data reported by De Wals and associatesassociates2626 and assuming 100% efficacy against types A, C, and assuming 100% efficacy against types A, C, Y and W135). - Y and W135). - Estimating the number needed to vaccinate to prevent Estimating the number needed to vaccinate to prevent diseases and death related to human papillomavirus infection diseases and death related to human papillomavirus infection Marc Brisson, PhD, Marc Brisson, PhD, Nicolas Van de Velde, MSc, Philippe De Wals, MD PhD, and Marie-Claude Boily, PhDNicolas Van de Velde, MSc, Philippe De Wals, MD PhD, and Marie-Claude Boily, PhDCan. Med. Assoc. J. 2007; 177: 464-468 Can. Med. Assoc. J. 2007; 177: 464-468

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Question: Did vaccines eliminate Question: Did vaccines eliminate diseases?diseases?

““Nearly 90% of the total decline in Nearly 90% of the total decline in mortality (scarlet fever, mortality (scarlet fever, diphtheria, , whooping cough, and measles) whooping cough, and measles) between 1860 and 1965 occurred between 1860 and 1965 occurred before the introduction of before the introduction of antibiotics and widespread antibiotics and widespread immunization.”immunization.” Illich, I. Illich, I. Medical NemesisMedical Nemesis. Chapter 1-The . Chapter 1-The Epidemics of Modern Medicine, NY: Bantam Books 1976Epidemics of Modern Medicine, NY: Bantam Books 1976

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Page 36: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Scarlet fever, typhoid fever and Scarlet fever, typhoid fever and pertussispertussis

Scarlet fever, typhoid fever and Scarlet fever, typhoid fever and pertussis were major killers.pertussis were major killers.

No vaccine was introduced for scarlet No vaccine was introduced for scarlet fever and typhoid fever.fever and typhoid fever.

All three diseases declined to virtually All three diseases declined to virtually zero.zero.

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Page 38: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2
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Polio vs Aseptic MeningitisPolio vs Aseptic Meningitis "Prior to 1954 any physician who reported paralytic poliomyelitis was doing his patient a "Prior to 1954 any physician who reported paralytic poliomyelitis was doing his patient a

service by way of subsidizing the cost of hospitalization and was being community-service by way of subsidizing the cost of hospitalization and was being community-minded in reporting a communicable disease. The criterion of diagnosis at that time in minded in reporting a communicable disease. The criterion of diagnosis at that time in most health departments followed the World Health Organization definition: "Spinal most health departments followed the World Health Organization definition: "Spinal paralytic poliomyelitis: signs and symptoms of nonparalytic poliomyelitis with the paralytic poliomyelitis: signs and symptoms of nonparalytic poliomyelitis with the addition of partial or complete paralysis of one or more muscle groups, detected on two addition of partial or complete paralysis of one or more muscle groups, detected on two examinations at least 24 hours apart." examinations at least 24 hours apart."

- Dr. Bernard Greenberg, Chairman of the Committee on Evaluation and Standards of - Dr. Bernard Greenberg, Chairman of the Committee on Evaluation and Standards of the American Public Health Associationthe American Public Health Association

In 1955 the criteria were changed to conform more closely to the definition used in the In 1955 the criteria were changed to conform more closely to the definition used in the 1954 field trials: residual paralysis was determined 10 to 20 days after onset of illness 1954 field trials: residual paralysis was determined 10 to 20 days after onset of illness and again 50 to 70 days after onsetand again 50 to 70 days after onset

Example: In one US county in July 1955 there were 273 cases of polio reported for 50 Example: In one US county in July 1955 there were 273 cases of polio reported for 50 cases of asceptic meningitis, compared to 5 cases of polio in 1966 and 256 cases of cases of asceptic meningitis, compared to 5 cases of polio in 1966 and 256 cases of aseptic meningitis.aseptic meningitis.

Page 40: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

In Canada, the Dominion Bureau of Statistics In Canada, the Dominion Bureau of Statistics issued an official bulletin in June 1959 titled issued an official bulletin in June 1959 titled Poliomyelitis Trends, 1958. "Data shown in this Poliomyelitis Trends, 1958. "Data shown in this report are confined to paralytic poliomyelitis only. report are confined to paralytic poliomyelitis only. It may be noted that the Dominion Council of It may be noted that the Dominion Council of Health at its 74th meeting in October 1958 Health at its 74th meeting in October 1958 recommended that for the purposes of national recommended that for the purposes of national reporting and statistics the term non-paralytic reporting and statistics the term non-paralytic poliomyelitis be replaced by 'meningitis, viral or poliomyelitis be replaced by 'meningitis, viral or aseptic,' with the specific viruses shown where aseptic,' with the specific viruses shown where known." known."

Page 41: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Flu Shot VideoFlu Shot Video

Page 42: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

THE PROBLEM?THE PROBLEM?

Page 43: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

THE PROBLEMTHE PROBLEM

Only 3 of the 10000+ strains are added Only 3 of the 10000+ strains are added each yeareach year

They are selected nine months in advance They are selected nine months in advance (to allow manufacturers time)(to allow manufacturers time)

The three strains are based on which ones The three strains are based on which ones are circulating in south east Asia at the are circulating in south east Asia at the timetime

There is NO GUARANTEE that those will There is NO GUARANTEE that those will be the strains circulating this “flu season”be the strains circulating this “flu season”

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HOW EFFECTIVE?HOW EFFECTIVE?

Last year, the strains were a non-matchLast year, the strains were a non-matchFor the first time ever, all three strains For the first time ever, all three strains

have been changed this yearhave been changed this year In the best years, the shot has been 0%-In the best years, the shot has been 0%-

14% effective14% effectiveEfficacy is measured by antibody response Efficacy is measured by antibody response

vs avoidance of diseasevs avoidance of diseaseMost people will show antibody response Most people will show antibody response

to influenza by the end of the seasonto influenza by the end of the season

Page 45: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

““POLICY vs EVIDENCE”POLICY vs EVIDENCE” BMJ Oct 26, 2006 - Summary points: Public policy worldwide recommends the use of inactivated

influenza vaccines to prevent seasonal outbreaks Because viral circulation and antigenic match vary each year

and non-randomised studies predominate, systematic reviews of large datasets from several decades provide the best information on vaccine performance

Evidence from systematic reviews shows that inactivated vaccines have little or no effect on the effects measured

Most studies are of poor methodological quality and the impact of confounders is high

Little comparative evidence exists on the safety of these vaccines

Reasons for the current gap between policy and evidence are unclear, but given the huge resources involved, a re-evaluation should be urgently undertaken

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Archives of Pediatric and Adolescent Medicine, Oct 2008: “significant influenza vaccine effectiveness could not be demonstrated for any season, age, or setting”

American Journal of Respiratory and Critical Care Medicine, Sept 2008: “no decrease in deaths from influenza and pneumonia despite the fact that vaccination rates have risen from 15% in 1980 to 65% now”

National Institute of Allergy and Infectious Disease: “We conclude that frailty selection bias and use of non-specific endpoints such as all-cause mortality have led cohort studies to greatly exaggerate vaccine benefits”

Cochrane Database of Systemic Reviews, 2006: A review of 51 studies involving 260000 children found no evidence that the flu vaccine is any more effective than a placebo

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SWINE FLUSWINE FLU

Symptoms are similar to seasonal flu, but Symptoms are similar to seasonal flu, but mildermilder

All deaths have had underlying health All deaths have had underlying health problemsproblems

In 1976, the Swine Flu vaccine killed more In 1976, the Swine Flu vaccine killed more people than the Swine Flu itselfpeople than the Swine Flu itself

Next fall expect recommendations for all Next fall expect recommendations for all people to be vaccinatedpeople to be vaccinated

Page 49: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

GARDASILGARDASIL

Gardasil has been marketed as a vaccine Gardasil has been marketed as a vaccine against cervical canceragainst cervical cancer

In fact, it is a vaccine for HPV – the virus In fact, it is a vaccine for HPV – the virus that causes genital wartsthat causes genital warts

In certain cases, genital warts can become In certain cases, genital warts can become cancerouscancerous

Problem: Only two strains of 200+ are in the Problem: Only two strains of 200+ are in the shot!shot!

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GARDASILGARDASIL

Problem: It was only studies in 1200 girls, of which Problem: It was only studies in 1200 girls, of which only 100 were 9 years old only 100 were 9 years old

Problem: Long tem side effects as well as Problem: Long tem side effects as well as effectiveness of vaccine have never been effectiveness of vaccine have never been studiesstudies

Problem: Less than 400 Canadian women die from Problem: Less than 400 Canadian women die from cervical cancer annually cervical cancer annually

Problem: there have been tens of thousands of Problem: there have been tens of thousands of adverse reactions, including 30+ deaths adverse reactions, including 30+ deaths attributed to the vaccineattributed to the vaccine

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GARDASILGARDASIL

PROBLEM: IS IT EVER REALLY A GOOD PROBLEM: IS IT EVER REALLY A GOOD IDEA TO INJECT NINE YEAR OLD IDEA TO INJECT NINE YEAR OLD GIRLS WITH THE VIRUS THAT CAUSES GIRLS WITH THE VIRUS THAT CAUSES GENITAL WARTS?GENITAL WARTS?

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HOW DANGEROUS ARE HOW DANGEROUS ARE VACCINES?VACCINES?

Exactly how many children are injured by Exactly how many children are injured by vaccines?vaccines?

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Doctors rarely report damage Doctors rarely report damage

““Doctors Doctors underreport underreport adverse vaccine adverse vaccine reactions by reactions by 90%.”90%.” US Food and US Food and Drug AdministrationDrug Administration "Investigative Report on the "Investigative Report on the Vaccine Adverse Event Reporting Vaccine Adverse Event Reporting System.“ NVIC.System.“ NVIC.

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“The company estimates about a 50-fold underreporting of adverse events in the passive reporting system.” Froeschle, J. Connaught Laboratories. Adverse events associated with childhood vaccines, evidence bearing on causality. Washington DC: Institute of Medicine presentations. 5/11/92; 328 Appendix. B. http://www.nap.edu/books/0309048958/html/R1.html

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One in 500 injuries reported…One in 500 injuries reported…

An analysis of the CDC’s own data An analysis of the CDC’s own data demonstrates that the number of actual demonstrates that the number of actual injuries from the rotavirus vaccine is 500 injuries from the rotavirus vaccine is 500 times the injuries reported to VAERS.times the injuries reported to VAERS.

http://search.cdc.gov/search97cgi/s97is.dll?queryText=Kaiser+Permanente+and+rotashield&SortField=score&Action=FilterSearch&Collection=CDCALL1&ResultTemplate=nsearchresult.hts&filter=newsearch.hts

http://www.cdc.gov/nip/ACIP/minutes/acip-min-oct01.rtf

Page 56: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2

Vaccine(s) Filed Compensated Dismissed Injury Death Total

DT (diphtheria-tetanus) 62 9 71 20 48DTP 3,281 695 3,976 1,263 2,674DTP-HIB 16 8 24 3 19DtaP 250 66 316 81 102DTaP-Hep B-IPV 25 10 35 4 4DTaP-HIB 6 1 7 3 0Td (tetanus-diphtheria) 128 2 130 51 53Tdap 4 0 4 0 0Tetanus 59 2 61 21 30Hepatitis A (Hep A) 11 0 11 1 3Hepatitis B (Hep B) 526 45 571 123 255Hep A- Hep B 4 0 4 3 1Hep B-HIB 3 0 3 2 1HIB 17 3 20 6 5HPV (human papillomarvirus) 4 0 4 0 0Influenza (Trivalent) 214 13 227 57 24IPV (Inactivated Polio) 260 14 274 7 264OPV (Oral Polio) 279 27 306 157 146Measles 142 19 161 54 107Meningococcal 4 0 4 0 0MMR (measles-mumps-rubella) 762 52 814 282 328MMR-Varicella 6 0 6 1 0MR 15 0 15 6 9Mumps 10 0 10 1 9Pertussis 5 3 8 2 6Pneumococcal Conjugate 23 3 26 5 13Rotavirus 31 1 32 20 11Rubella 189 4 193 70 123Varicella 40 2 42 21 13

TOTAL 11,757 994 12,746 2,266 4,755

Page 57: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2
Page 58: Childhood Vaccinations: Questions All Parents Should Ask - BCC Vaccine Talk 2