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Chest Physiotherapy and Airway Clearance in Pediatrics
Rob DiBlasi RRT-NPS, FAARCProgram Manager Research/QI, Respiratory TherapyPrinciple Investigator, SCRIMarch 22, 2017
Conflict of Interest
I have no real or perceived conflict of interest that relates to this presentation. Any use of brand names is not in any way meant to be an endorsement of a specific product, but to
merely illustrate a point of emphasis.
Objectives
Learning objectives for this presentation: Discuss different forms of airway clearance
therapies (ACTs) Review the literature related to the use of
ACTs in pediatric lung disease Discuss ways to embrace judicious use of
ACTs in patients using evidence-based approaches
Background
Airway Clearance Techniques (ACTs) are used in variety of settings for a variety of clinical ailments:
1) evidence of retained pulmonary secretions 2) weak or ineffective cough 3) focal lung opacity on chest x-ray consistent with mucous plugging and/or atelectasis and 4) intrapulmonary shunt requiring oxygen
ChestPhysiotherapy
PosturalDrainage
http://www.cfbarbados.org/content/treatment
ChestPhysiotherapy
Other Airway Clearance Options: ACTs
Therapy Vest
Hand-Held Airway Clearance
Cough Assist
Nasotracheal Sx
ACTs contd
Incentive Spirometry
Ambulation
Breathing games
Literature Search
ACTs have only been shown to be effective in children with CF, Bronchiectasis and neuromuscular weakness
Lack of definitive data for ACT for common forms of pediatric respiratory failure Pneumonia (may cause patients condition to worsen) Bronchiolitis, asthma, pleural effusion Prevention of atelectasis
Bronchiolitis
Systematic review to determine efficacy of CPT in infants with acute viral bronchiolitis
Are ACTs a useful option with pneumonia?
Pneumonia
RCT with children (29 d to 12 y old) hospitalized with acute pneumonia, and compared twice-daily CPT and standard pneumonia therapy (n =51) to standard treatment alone (n =47) The CPT group had a longer median duration
of coughing (5.0 d vs 4.0 d, P =0.04) and longer duration of rhonchi (median 2.0 d vs 0.5 d, P= 0.03) than the medical treatment only group
Paloudo, Thorax, 2008
ACT in Asthma
Randomized Placebo Controlled Trial 38 children aged 6 to 13 years with severe
asthma 19 children received chest physical therapy
(PT) and 19 children received placebo visits Lung function at the end of the study was
similar in both groups
Asher I et al., Pediatr Pulmonol, 1990
Can ACT resolve acute lobar atelectasis during mechanical ventilation?
Larger ventilated patients (Templeton M et al., Intensive Care Med,2007) CPT may be useful for acute lobar or segmental
atelectasis based on radiographic evidence Neonates-post-extubation (Flenady et al.,
Cochrane 2002) No benefit to peri-extubation CPT No decrease in post-extubation lobar collapse Lower re-intubation rate in babies treated with CPT
Can CPT and other ACTs prevent atelectasis?
CardiacTransplant
CXRfrom4/15/15.CPTorderedTID.Reasonfororder:LobarAtelectasis.Radiologistnotednofocalinfiltrateson4/15/15.
CXRfrom4/16/15.CPTprovidedTID.Radiologistnotedlungsaresomewhatoverinflatedmildshadowingininfrahilar areas
RoomAirHHFNC46L/min
TricuspidAtresiaRoomAirHFNC5L/minfor72hours
4/14MildPerihilarhazinesssuggestiveofedemaReceivingCPTTIDtoRULRTattemptedtogetthisDCdMD:well,Iguessyouaregoingtohavetodoitanyway.RT:howaboutincreasingPEEP?
4/16/15RadiologistnotedNolobarconsolidationCPTreorderedforRightsidedlobarcollapse.
4/16/150610CPTQ4for72hoursRadiologistnotedmildincreaseinRULopacityCosttopatient:$6,300.00RTtime:6hoursatthebedside
6L/minHHFNCFiO235
4/14/15Orderedforlefthemidiaphragmparesisandthenorderchangedtolobaratelectasis
Can ACT prevent lobar atelectasis or VAP?
Mechanically ventilated adult patients (Chen YC, J Clin Med Assoc, 2009) No differences in VAP between CPT and no intervention
ACT in pleural effusion
Systematic Review
Included 24 RCTs, seven crossover RCTs, and one prospective cohort study in adults and patients (n=2,453)
Patients with CF and neuromuscular disease were excluded
Based on these data, this review found no evidence from RCTs to support the use of CPT or any other form of ACT in adults or pediatrics to: improve oxygenation, reduce length of time on the ventilator, reduce
stay in the ICU, resolve atelectasis/consolidation, and/or improve respiratory mechanics versus usual care in this population
Andrews et al., Resp Care, 2013
Evidence Based Review-Pediatrics
Andrews et al., Resp Care, 2013
Risks Associated with ACT
Gastroesophageal reflux (Button BM, Pediatr Res 1994)
Decreased oxygenation and increased oxygenation requirements (Hough JL, Cochrane, 2008)
Rib fracture (Purchit DM, Am J Dis Child, 1975)
Increased intracranial pressure and intracranial bleeding (Harding JE, J Pediatr, 1998)
Longer duration of fever (Britton S, BMJ, 1985)
Increased vomiting and respiratory instability (Roque et al., Cochrane, 2012)
Increased SOB, arrhythmia, bronchospasm, thoracic hematoma (Andrews J, Resp Care, 2013)
Photo courtesy of Seattle Childrens Hospital RT Dept with permission
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/200
96/
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/200
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/200
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/19/
2009
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/23/
2009
1/24
/201
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26/2
010
3/30
/201
05/
2/20
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3/20
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6/20
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8/20
1010
/11/
2010
11/1
2/20
1012
/15/
2010
1/16
/201
12/
20/2
011
3/25
/201
14/
26/2
011
5/31
/201
17/
4/20
118/
5/20
119/
8/20
1110
/14/
2011
11/2
0/20
1112
/23/
2011
2/3/
2012
3/18
/201
24/
28/2
012
6/2/
2012
7/13
/201
28/
19/2
012
9/25
/201
211
/13/
2012
12/2
5/20
121/
29/2
013
3/3/
2013
4/10
/201
35/
17/2
013
6/27
/201
38/
3/20
139/
7/20
1310
/16/
2013
12/1
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24/2
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3/12
/201
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/201
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7/29
/201
4
Problem: RT Staffing CrisisD
aysh
ift R
T FT
E
0
400
800
1200
1600
2000
2400
2011 2012 2013 2014
# C
hest
Phy
siot
hera
py C
harg
es
JanFebMarApr
Allocation of RT resources: Airway Clearance
$548,310
$908,670 $1,017,660
$1,431,150
Reasons other than those indicated in the order set
prevention of lobar atelectasis, diffuse pneumonia, increased work of breathing, inability to clear secretions, obstruction of V-P shunt and pleural effusion, complete lung opacification while on extracorporeal life support, wheezing, microaspiration, comfort (soothing), decreased breath sounds, no abdominal domain, poor pulmonary compliance, bronchiolitis, excessive nasal and/or oral pooling, junky breath sounds, , post-operative fever and paroxysmal cough.
Goal
WeproposedatherapistdrivenprotocolthatallowsRTstoprovideappropriateandjudiciousACTcaretopatients Lessrisktothepatient Lessexpensetopayers LessstrainonRTresources ImprovedjobsatisfactionforRTs
UCL 0.28
CL 0.20
LCL 0.12
0.00
0.10
0.20
0.30
0.40
0.50
0.601/
1/12
1/20
/12
2/8/
122/
27/1
23/
17/1
24/
5/12
4/24
/12
5/13
/12
6/1/
126/
20/1
27/
9/12
7/28
/12
8/16
/12
9/4/
129/
23/1
210
/12/
1210
/31/
1211
/19/
1212
/8/1
212
/27/
121/
15/1
32/
3/13
2/22
/13
3/13
/13
4/1/
134/
20/1
35/
9/13
5/28
/13
6/16
/13
7/5/
137/
24/1
38/
12/1
38/
31/1
39/
19/1
310
/8/1
310
/27/
1311
/15/
1312
/4/1
312
/23/
131/
11/1
41/
30/1
42/
18/1
43/
9/14
3/28
/14
4/16
/14
Trea
tmen
ts p
er P
atie
nt D
ay
Calendar Days
Total Tx Per Patient Day- All PatientsPatients with moderate-high level evidence for ACT use: 67% increase
All Patients, All Diseases: All Airway Clearance Therapies
Patients with low level evidence for ACT use: 65% increase
UCL 0.11
CL 0.07
LCL 0.03
-0.05
0.00
0.05
0.10
0.15
0.20
0.25
0.30
1/1/
121/
19/1
22/