chemistry year Œ book 2001 - sci.muni.cz · chemistry year Œ book 2001 faculty of science masaryk...

Chemistry

Year � Book 2001 Faculty of Science

Masaryk University Brno

Masaryk University Brno, Czech Republic, 2001

Section Chemistry

Chemistry Section is a unit of the Faculty of Science housed in three buildings at Kotlarska street and partly also outside at Kamenice street. Encompassing about one hundred academic staff, it offers a quality chemical education in a chemistry graduate programme leading to a master degree in several area of specialization (analytical chemistry, biochemistry, environmental chemistry, inorganic chemistry, macromolecular chemistry, organic chemistry and physical chemistry). In addition, a separate bachelor´s program is available to qualify the students for the applied biochemistry. Graduate students may enter into the respective Ph.D. programmes.

Teaching activities are supported by a necessary research environment. A broad spectrum of modern chemical instruments enables thorough studies on chemical synthesis, molecular structure determination, trace element analysis and kinetics and mechanisms of chemical and biochemical processes, just to mention a few. There exists a significant cooperation with many universities and research institutes in Western Europe and U.S.A. ORGANIZATIONAL STRUCTURE OF THE CHEMISTRY SECTION: the Office Head Igor Kučera (Prof., RNDr., D.Sc.) Deputy Head Jiří Pinkas (Assoc.Prof., RNDr., Ph.D.) Secretary Stanislava Fousová the Departments Analytical Chemistry Biochemistry Inorganic Chemistry Organic Chemistry Theoretical and Physical Chemistry the Laboratories Laboratory of Atomic Spectrochemistry and Research Centers Computer Laboratory

NMR Laboratory Research Center for Environmental Chemistry and Ecotoxicology

Department of Analytical Chemistry with Division of Chemometrics

TEACHING AND RESEARCH ACTIVITIES

The department provides education in analytical chemistry including chemometrics: in bachelor studies for students of chemistry, biochemistry, biology and environmental science, in master studies for students of chemistry, biochemistry and environmental science, in postgraduate studies for specialists in analytical chemistry. External teaching activity also comprises basic, advanced and special lectures on analytical chemistry at the Faculty of Chemistry, Technical University, Brno.

The research involved the development of new analytical procedures and study of natural and newly synthesized substances (drugs, peptides, humic acids etc.). Increasing accent was put on the development of new methods and instrumentation in the emerging field of bioanalytical chemistry. New analytical methods and approaches suitable for the determination of analytes in samples with complex matrix were developed. Chemometrical techniques such as Artificial Neural Networks combined with experimental design were routinely applied to optimize analyses. Attention was also paid to thermodynamic and kinetics study of complexation of transition metal ions (platinum group metal ions, copper(II), etc.) by various macrocyclic compounds, chemical model determination (equilibria, kinetics), chemical modelling (natural processes), chemistry of less common metals (f-elements, platinum metals, thallium, etc.), biocoordination chemistry (humic acids, macrocycles, drugs, etc.).

Capillary Electrophoresis (CE) was used for the study of humic substances of different origin (the study of oligomerisation, metal ion complexation, etc.). Also method for determination of some important analytes (sorbic acid, resveratrol, etc.) in wines was developed. Rapid screening methods for drug content of some drugs mentioned above in biological liquids were worked out and validated methods for determination of antiviral drugs like memantine and rimantadine were developed. CE instrumentation was also applied to determine chiral impurities. A CE instrument with laser-induced fluorescence detection was built in the department for both research and teaching purposes.

Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI MS) played a key role in analysis and structural elucidation of biological compounds, such as peptides, peptide complexes and humic acids. In addition, it also served as a tool for analysis of small organic and inorganic compounds. Significant attention was paid to advanced sample preparation for an automated identification of proteins.

A chromatographic method for the analysis of adenine and cytosine as build-block molecules of DNA by reversed phase high performance chromatography (HPLC) was developed and compared with other techniques (CE, MALDI-TOF MS). In collaboration with industrial company, intensive study of reactive dyes by means of different experimental techniques was done.

Atomic absorption spectrometry (AAS) was used for the determination of metals, such as copper in biological samples. Dialysis and electrodeposition was applied for preconcentration of metals in flame AAS. The differentiation of free metal ions in the presence of complexing agents and humic acids was studied by using circulating dialysis through different membranes.

In Laboratory of atomic spectrochemistry, research activities are common with departmental. More details are given in a separate section.

DEPARTMENT STAFF

Head: Josef Havel (Prof., RNDr., D.Sc.) Professor: Lumír Sommer (RNDr., D.Sc.), Professor Emeritus Associate Professors: Vratislav Chromý (Ing., CSc.), part time Viktor Kanický (RNDr., D.Sc.) Josef Komárek (RNDr., D.Sc.) Vítězslav Otruba (RNDr., CSc.) Assistant Professors: Marta Farková (RNDr., CSc.) Jan Havli� (Mgr., Dr.) Přemysl Lubal (Mgr., Dr.) Karel Novotný (Mgr., Dr.) Jiří Pazourek (RNDr., Dr.) Jan Preisler (Mgr., Dr.) Jaroslav �enkýř (Ing., CSc.) Research Assistants: Dagmar Gajdo�ová (Ing.) Pavel Krásenský (Ing.) Klára Novotná (Ing.), part time Nadě�da Pollaková (Ing.), retired Technical Assistants: Helena Zavadilová (Ing.) Jitka Nováková Secretary: Iva �afaříková Adjunct Lecturers: Milo� Bartu�ek (Prof., RNDr., CSc.) Petr Boček (Prof., RNDr., D.Sc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Milan Dressler (Assoc. Prof., RNDr., CSc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Franti�ek Foret (Ing., CSc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Ludmila Křivánková (Assoc. Prof. RNDr., CSc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Miroslav Macka (RNDr., Ph.D.), University of Tasmania, Hobart, Australia. Karel �lais (Assoc. Prof., RNDr., D.Sc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno. Radim Vespalec (Assoc. Prof., Ing., D.Sc.), Institute of Analytical Chemistry, Academy of Sciences CR, Brno.

Ph. D. Students: Full Time: Vlastimil Dohnal (Mgr.) Milo� Halúzka (Mgr.) Ale� Hrdlička (Mgr.) Radek Chalupa(Mgr.) Alice Kotulánová(Mgr.) Jiří Machát (Mgr.) Jiří Maleček (Mgr.) Sabina Malovaná (Mgr.) Martin Muzikář (Mgr.) Eva Niedobová (Mgr.) Lenka Pokorná (Mgr.) Pavla Polá�ková (Mgr.) Lubomír Proke� (Ing.) Martin Semerád (Mgr.) Jitka Studýnková (Mgr.) Martin �těpán (Mgr.) Markéta Va�ková (Mgr.) Partial Time: Lenka Babáčková (Mgr.) Klára Novotná (Ing.) Marie Pi�těková (RNDr.) Michal Spě�ný (Ing.) �árka Winklerová (RNDr.)

FOREIGN Ph.D. STUDENTS AT THE DEPARTMENT:

Gaston Bocaz Beneventi (Universidad de Concepcion, Concepcion, Chile)

Maria L. Pacheco Hernandéz (UAM, Mexico D. F., Mexico)

Julio A. Soto Guerrero (UNAM, Mexico D. F., Mexico)

FOREING STUDENTS AT THE DEPARTMENT

Silvia Perez (Universidad de Girona, Spain), 3 months

Antonio Molina (University of Cordoba) 3 months

THESES DEFENDED IN THE ACADEMIC YEAR 2000/2001

Diploma Theses:

Milo� Halúzka � Analysis of Thin Layers using Laser Ablation with Optical Emission Spectrometry in Inductively Coupled Plasma (supervisor: V. Kanický) Eva Paděrová � Serial Alkalic Phosphatase and Possible Influencing of Its Activity using Additives (supervisor: V. Chromý) Marie Sobotková � Determination of Alkali Metals using the Method of Laser Ablation with Flame Emission Spectrometry (supervisor: V. Otruba) Jitka Studýnková � Determination of Selenium using Optical Emission Spectrometry with Inductively Coupled Plasma and Hydride Generation (supervisor: V. Kanický) PhD Thesis:

Lenka Pokorná � Humic Substances: Natural Supramolecular Ensembles (supervisor: J. Havel)

CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT MEMBERS

Farková, M., Lubal, P., �enkýř, J.: Chemical Olympiad (south Moravian round, practical part).

Havel, J., Farková, M. Artificial Neural Networks in Chemistry, Brno, November 2002.

PROJECT GRANTS RECEIVED

Ministry of Education and Youth of the Czech Republic, 541/2001

Farková, M.: Innovation of chemometrics education.

Ministry of Education and Youth of the Czech Republic, Programme of Intensification of Research at Universities CEZ:J07/98:143100011

�ák, Z. and coworkers: Structure and bonding relationships, properties and analysis of synthetic and natural molecule ensembles, part Bioanalytical Laboratory (Havel, J.).

Ministry of Education and Youth of the Czech Republic, Program of Intensification of Research at Universities CEZ:J07/98:143100007

Pro�ek, P. and coworkers: Ecology of coast Antarctic vegetation oasis (Havel, J.).

Ministry of Health of the Czech Republic, IGA MZ 5059-3

Responsible holder: Center of Cardiovascular and Transplant Surgery, Brno, Benedík, J.: Heart arrest by the use of esmolol under normothermic perfusion during ECC. Comparison with crystalloid and blood cardioplegia. Collaboration: Havel, J., Gajdo�ová, D. and Malovaná, S.

EU COST, D8/0001/97

Resposible holder: Department of Inorganic Chemistry, Faculty of Natural Sciences, Charles University, Luke� I.: Rational Design of Lanthanide Chelates for Biomedical Applications. Collaboration: Havel, J., Lubal, P.

INDUSTRIAL COOPERATION

Institute for state control of veterinary biopreparations and drugs, Brno: The determination of antihormones. Collaboration : Havel, J.

PLIVA-Lachema a.s.: Stability tests of memantin and rimantadin. Collaboration: Havel, J., Gajdo�ová, D., Pazourek, J., Polá�ková, P.

Radioactive Waste Repository Authority, Prague : Thermodynamic database II. Collaboration: Havel, J., Lubal, P.

OECD NEA, Paris, France: Thermodynamic database. Havel, J., Lubal, P.

INVITED LECTURES AND RESEARCH STAYS OF STAFF ABROAD

Havel J., Artificial Neural Networks in Chemistry, GlaxoSmithKline, Verona, June 6, 2001, Italy. (Invited Lecture). Havli�, J., � April, one week stay at University of Szeged, Faculty of Science, Dept. of Inorganic and Analytical Chemistry, Hungary, Dr. Antal Peter.

Havli�, J. � since October 1, postdoctoral stay at Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany.

Lubal, P. � June - one weak stay as visiting professor at Universidad de Salamanca, Spain.

Preisler, J. � till February 14, completion of 1 year research stay at Barnett Institute, Boston, USA.

Preisler, J. � June and October, one week stays at Barnett Institute, Boston, USA.

OTHER INTERNATIONAL CONTACTS AND CO-OPERATION OF STAFF

Cooperations

Université Louis Pasteur, Ecole Européenne des Hautes Études des Industries Chimiques de Strasbourg, Department of Bioinorganic Chemistry, Strasbourg, France (Prof. A.-M. Albrecht-Gary; J. Havel).

Université Paris 7, France (Prof. J.-P. Doucet; J. Havel).

Free University Brussels, Farmaceutical Institute, Belgium (Prof. D. L. Massart; J. Havel, J. Pazourek)

University of Tasmania, School of Chemistry, Australia (Prof. P. R. Haddad; J. Havel)

Ecole d`Ingénieurs en Génie des Systémes Industriels, EIGSI, La Rochelle, France (Prof. J. A. Videau; J. Havel).

Université Claude Bernard - Lyon I, Laboratoire des Sciences Analytiques, Lyon, France (Prof. J.-M. Mermet; V. Kanický, V. Otruba).

Veterinary and Agrochemical Research Centre, Section of Ecochemistry and Spectroscopy, Tervuren, Belgium (Dr. M. Hoenig; V. Kanický, V. Otruba)

Technical University Ko�ice, Faculty of Metallurgy, Department of Chemistry, Ko�ice, Slovak republic (Prof. E. Krakovská; V. Otruba)

University of Vienna, Dept. of Analytical Chemistry. Division of Atomic Spectroscopy, Vienna, Austria (Prof. I. Steffan; V. Kanický)

University of Cordoba, Faculty of Science, Department of Physics (Prof.. Carmen M. Quintero; V. Otruba, V. Kanický)

Universidad de La Laguna, Dept. of Analytical Chemistry, La Laguna, Tenerife, Spain (Prof. J. J. Arias, L. Galindo, E. M. Pena, F. Montelongo, J. P. Perez Trujillo; J. Havel).

Universidad Autónoma de Barcelona, Bellaterra, Spain (Prof. M. Valiente; J. Havel).

Universidad National Autónoma de Mexico, UNAM, Mexico (Prof. A. Rojas-Hernández; J. Havel).

Universidad Autónoma de Mexico, UAM, Cuatitlán, Mexico (Prof. G. Pérez-Caballero; J. Havel).

Universidad Nacional de Cordoba, Facultad de Ciencias Químicas, Departamento de Fisicoquímica, Córdoba, Argentina (Prof. Carlos de Pauli; J. Havel).

Universidad de Salamanca, Department of Physical Chemistry, Salamanca, Spain (Prof. J. L. González; J. Havel, P. Lubal).

San José State University, California, U.S.A. (Prof. L. Yengoyan; J. Havel).

The Royal Institute of Technology, Department of Inorganic Chemistry, Stockholm, Sweden (Prof. I. Grenthe, Prof. M. Muhammed; J. Havel).

The R.W. Johnson Pharmaceutical Research Institute, Raritan, New Jersey, USA, (Dr. N. A. Guzman; J. Havel).

Dionex, Inc. U.S.A. (Dr. P. Jandik; J. Havel).

Adam Mickiewicz University, Department of Water and Soil Analysis, Poznan, Poland (Prof. J. Siepak; V. Kanický).

Eidgenossische Technische Hochschule, Department of Inorganic Chemistry, Zürich, Switzerland, (Prof. G. Anderegg; J. Havel; P. Lubal).

Eidgenossische Technische Hochschule, Department of Inorganic Chemistry, Zürich, Switzerland, (Prof. D. Guenther; V. Kanický).

M. V. Lomonosov University, Department of Analytical Chemistry, Moscow, Russia (Prof. V. M. Ivanov, Yu. A. Zolotov; L. Sommer; J. Havel).

Universidad de Barcelona, Barcelona, Spain (Prof. R. Tauler; J. Havel, P. Lubal).

Barnett Institute, Northeastern University, Boston, USA (Prof. B. Karger, Prof. G. Davies; J. Preisler; J. Havel).

Foreign visitors

M.C. Trinidad Martinez C. (Prof., Dr.), UNAM, Mexico, one-week stay.

Eladia M. Peña-Méndez , (Prof., Dr.), Universidad de La Laguna, Tenerife, Spain, visiting professor.

Li Hua (Prof.) , Northwest University, Shaanxi, China, a half year visiting professor.

Mermet Jean-Michel (Dr.), Laboratoire des Sciences Analytiques, Université Claude Bernard, Lyon I, Villeurbanne, France, one-week stay.

Students Studying Abroad

Vlastimil Dohnal, Universidad de La Laguna, Tenerife, Spain, 4 months SOCRATES/ERASMUS study scholarship, doctorate study.

Martin Muzikář, Universidad de Girona, Spain, 3 months SOCRATES/ERASMUS study scholarship, doctorate study.

Ivona Svobodová, Universidad de Salamanca, Spain, 6 months SOCRATES/ERASMUS study scholarship.

OTHER PROFESSIONAL ACTIVITIES

Havel, J.:Head of the Division of Chemometrics of the Department of Analytical Chemistry, Masaryk University; Member of the Editorial Board of the Journal of Chemometrics and Intelligent Laboratory Systems; Member of the Editorial Board of Folia Fac. Sci. Nat. Masaryk. Univ.; Member of the International Society for Chemometrics; Member of the Working Party for Chemometrics of the Czech Chemical Society; Member of the Committee of the Regional Branch of the Czech Chemical Society; Member of the Spectroscopic Soc. of J. M. Marci, Prague; Member of the New York Academy of Sciences, Chairman of the Council for Doctoral Studies in Analytical Chemistry, the Masaryk University; Member of the Coucil for Doctorate Studies in Analytical Chemistry at Charles University in Prague, Member of the Council for Doctorate Studies in Analytical Chemistry at the College of Chemical Technology, Prague; Member of the Scientific Council of the Faculty of Sciences of the Masaryk University; Member of the Council for Doctoral Studies in Analytical Chemistry at Slovak Academy of Sciences, Bratislava, Slovak Republic, Member of International Geographic Society, Member of Americal Association for the Advancement of Science(AAAS).

Kanický, V.: Member of the Committee of the Spectroscopic Soc. of J. M. Marci, Prague; Vice-Chairman of the Working Party of Analytical Chemistry of the Czech Chemical Society; ; Deputy Head of the Laboratory of Plasma Sources for Chemical Analysis of the Faculty of Science, the Masaryk University Brno; Member of the Scientific Council of the Faculty of Sciences, the Masaryk University; Vice-dean of the Faculty of Science, the Masaryk University.

Komárek, J.: Deputy Head of the Department of Analytical Chemistry; Member of the Council for the Doctorate Study in Analytical Chemistry and Environmental Chemistry at the Masaryk University Brno.

Lubal, P.: Deputy Head of the Department of Analytical Chemistry (till June).

Otruba, V.: Head of the Laboratory of Plasma Sources for Chemical Analysis

Preisler, J.: Deputy Head of the Department of Analytical Chemistry (since July). Member of American Chemical Society, Member of American Society for Mass Spectrometry, Member of the Committee of the Regional Branch of the Czech Chemical Society.

Sommer, L.: Professor Emeritus, Member of the Working Party for Chemistry of the Commission for Accreditation of the Czech Government; Emeritus Member of the Commission for Analytical Reactions, Reagents and Separations, IUPAC; Member of the Council for Postgraduate Studies in Analytical Chemistry, the Masaryk University; Member of the Scientific Council of the College of Chem. Technology, Prague; Member of the Councils for Postgraduate Studies in Analytical Chemistry: Technical Univ. Prague and Palacký Univ. Olomouc; Member of the Working Party of Analytical Chemistry of the Czech Chemical Society; Member of the Spectroscopic Soc. of J. M. Marci, Prague; teaching at the Faculty of Chemistry of the Technical University Brno.

Department of Biochemistry


Department of Biochemistry arranged for teaching of the basic biochemical disciplines at the bachelor and master levels for students of chemistry, biology, and future high school teachers of our Faculty. In addition, specialized education of graduate students of biochemistry and some branches of biology (e.g., molecular biology) was carried out.

New students were accepted for graduate study. We guaranteed the teaching of 31 students in 4th and 5th year and 15 graduate students. The staff of the department participated in many national and international congresses. The department organized International Net Conference of Diploma Theses with participation of several Czech and Slovak Universities. In 2001, a new Laboratory of Proteom Research was opened in cooperation with Chemistry and Biology sections equipped with a high tech mass spectrometer TOF-100 reflex TMMALDI TOF MS system (Bruker), ESQUIRE2000TM (ion trap) and 2D-electrophoretic system.

Research activities are oriented to the topics studied in the following laboratories:

Laboratory of biochemistry of plant-pathogen interactions (V. Mike�, J. Mazoch, V. Kratochvílová),

Laboratory of biosensors (P. Skládal),

Laboratory of environmental biotechnology (M. Mandl, O. Janiczek, H. Řičánková)

Laboratory of microbial bioenergetics (I. Kučera, P. Boublíková, Rotrekl, V., J. Neu�ilová),

Laboratory of separation of biomolecules (Z. Glatz, P. Zbořil, M. Wimmerová, L. Poláková),

Laboratory of proteom research (P. Bouchal, cooperation with the permanent staff)

Our research was supported almost exclusively by external sources: Grant Agency of the Czech Republic, Fund of the Development of Universities, research projects sponsored by foreign institutions, including 4th and 5th Frame Programs of the European Union and bilateral programs. The most of the research workers participated in Research Program of the Ministry of Education. Some research activities were carried out in cooperation with Academy of Science of Czech Republic (animal biochemistry - S. Pavelka) and National Centre for Biomolecular Research (M. Wimmerová).

DEPARTMENT STAFF

Head: Vladimír Mike� (Assoc. Prof., RNDr., CSc.) Professor: Igor Kučera (RNDr., D.Sc.) Associate Professors: Zdeněk Glatz (RNDr., CSc.) Martin Mandl (Ing., CSc.) Petr Skládal (RNDr., CSc.) Petr Zbořil (RNDr., CSc.) Assistant Professors: Pavla Boublíková (RNDr., CSc.) Oldřich Janiczek (RNDr., CSc.) Stanislav Pavelka (RNDr., CSc.) Vladimír Rotrekl (Mgr, Ph.D.) Michaela Wimmerová (RNDr., Ph.D.) Research Assistants: Pavel Bouchal (Mgr.) �árka Helánová (Mgr.) Michal Kuňák (Mgr.) Jiří Mazoch (Mgr.) Ivo Pluháček (RNDr.) Technicians: Věra Kratochvílová Hedvika Řičánková Jitka Neu�ilová Ludmila Poláková Secretary: Stanislava Fousová Adjunct Lecturers: Arno�t Kotyk (Prof., RNDr., D.Sc.), Institute of Physiology, Czech Academy of Sciences, Prague Petr Breinek (RNDr.), Faculty Hospital St. Anna, Brno Petr Pečínka (RNDr., CSc.), Institute of Biophysics, Czech Academy of Sciences, Brno Ph.D. Students: Full time Pavel Bouchal (Mgr.) Pavla Če�ková (Mgr.) Lenka Drábková (Mgr.) Gabriela Fanfrdlová (Mgr.) Jiří Friml (Mgr.) Jan Halámek (Mgr.) �árka Helánová (Mgr.) Andrea Ka�ná (Mgr.) Jitka Ka�parovská (Mgr.)

Tomá� Ka�parovský (Mgr.) Michal Kuňák (Mgr.) Iva Navrátilová (Mgr.) Soňa Nováková (Mgr.) Petra �evčíková (Mgr.) Renáta Solná (Mgr.) Jiří �eravík (Mgr.) Part time Iva Bartáková (Mgr.) Ivana Huvarová (Mgr.) Jiří Mazoch (Mgr.) Jana Sýkorová (Mgr.) Radek Tesařík (Mgr.) Nikola Zelinková (Mgr.)


Diploma theses: BRZEZINOVÁ, M. Isolation and purification of the lactate dehydrogenase from Leuconostoc lactis (supervisor P. Zbořil).

CZERNEKOVÁ V. Purification of dehalogenase from Mycobacterium avium (supervisor M. Wimmerová).

DAVIDOVÁ, I. Tetrathionate hydrolase in Thiobacillus ferrooxidans (supervisor O. Janiczek).

HOLÝ, L. Using of the affinity chromatography for isolation of iLDH from Paracoccus denitrificans (supervisor P. Zbořil).

HRABINCOVÁ, E. The DNA diagnostic of patients with non-PKU hyperphenylalaninemia (supervisor L. Fajkusová).

KALETOVÁ, S. The method for determination of activity of enzymes producing sulfite (supervisor O. Janiczek).

KUCHAŘÍKOVÁ, I . Interactions of p53 with antibodies and DNA studied using piezoelectric biosensors (supervisor P. Skládal).

MASAŔÍK, M. The influence of antidepressants on thyroid hormones metabolism in brain and other tissues: Experimental studies in rats (supervisor S. Pavelka).

NOVÁKOVÁ, S. Application of capillary zone electrophoresis for evaluation activity of enzymes (supervisor Z. Glatz).

PROCHÁZKOVÁ, B. Purification and properties of glyoxylate oxidase from the brown�rot basidiomycete Fomitopsis pinicola (supervisor V. Mike�).

SOLNÁ, R. Electrochemical immunosensors for detrmination of pesticides (supervisor P. Skládal).

�TĚRBOVÁ, H. Application of micellar elektrokinetic capillary chromatography for the analysis of Schisandra extract (Schisandra chinensis) (supervisor Z. Glatz).

ZELINKOVÁ, N. Expresion of isotopically labeled protein for NMR (supervisor M. Wimmerová).

ZMIDLOCH, J. Activity of Acidithiobacillus ferrooxidans on pyrite and sulfur (supervisor M. Mandl).

Ph.D. thesis ČE�KOVÁ, P. Metabolism of sulfur and sulfur compounds in Thiobacillus ferrooxidans (supervisor M. Mandl).


JANICZEK, O., MIKE�, V., ZBOŘIL, P., MANDL, M. International Net Conference of Diploma Theses. Brno, Czech Republic, June 2001.

JANICZEK, O., GLATZ, Z. Conference of student research activities in chemistry. May 2001

SKLÁDAL P. Member of the Scientific Committee, VIth International Conference on Agri-Food Antibodies. Prague, October 2001.

SKLÁDAL P. Member of the Scientific Committee, Joint Copernicus Meeting Biosensor for Environmental Monitoring and Food Control, Moscow, Russia, June 2001.

ZBOŘIL, P. Organization of the PhD student conference in English (section of young scientists at 5th Workshop of Biochemists and Molecular Biologists, Brno; Organization of the Tempus course Immunoassays in food and environmental analysis (Masaryk University, Brno, February 2001).

WIMMEROVÁ, M. Member of the Organizing Committee, 5th Workshop of Biochemists and Molecular Biologists, Masaryk University, Brno, February 2001.


Grant Agency of the Czech Republic 203/01/1589 KUČERA, I.: Mechanisms involved in regulation of respiratory systems in denitrification bacteria by environmental factors.

525/00/0785 MANDL, M.: Acidification processes in sulfide wastes.

203/00/P097

ROTREKL, V.: Identification of genes involved in nitrate transport in P.denitrificans and basic characterisation of their products.

Fund of the Development of Universities 569/2001 BOUCHAL, P.: The study of a bacterial proteome using 2-D electrophoresis.

579/2001 GLATZ, Z., �TĚRBOVÁ, H: Capillary electrochromatography in polymeric columns.

586/2001 KA�PAROVSKÝ, T., MIKE�, V.: Interaction of sterol elicitors with plant cells.

593/2001 KUŇÁK, M.: Mass spectrometry in monitoring of geseous metabolites.

595/2001 MIKE�,V., LOCHMAN, J.: Molecular biological methods of discrimination of Armillaria species.

558/2001 ROTREKL, V.: Development of a course on proteomics and recombinant techniques.

602/2001 �EVČÍKOVÁ, P., GLATZ, Z.: �On-column� derivatization in capillary electrophoresis.

Foreign grants CME-03617-97 KÁ�, J. (local coordinator ZBOŘIL, P.): Environmental issues in university education (TEMPUS Phare).

99063-3 MIKEŚ, V.: Study of the effect of elicitins, fungal proteinaceous elicitors stimulating plant defence reaction. Bilateral international project (Project Barrande, France-Czech Republic). ERB-IC-15-CT96-0804 NIKOLELIS, D., SKLÁDAL, P., et al.: Biosensors for direct monitoring of environmental pollutants in field (EU - INCO Copernicus).

QLK3-CT-2000-01481 RUZGAS, T., SKLÁDAL, P., et al.: Intelligent signal processing of biosensor arrays using pattern recognition for characterisation of wastewater: Aiming towards alarm systems. INTELLISENS (EU - 5th Frame Program).

ERB-IC15-CT98-0910 SKLÁDAL, P. (coordinator): Multichannel electrochemical biosensor for rapid food safety monitoring - MEBFOOD (EU - INCO Copernicus).

Other grants ME 321 Contact MIKE�, V.: Study of the elicitor effects (Czech Ministry of Education).

NJ/6109-3 PAVELKA, S.: Interference of bromide from the environment with the metabolism of iodine in the thyroid and other tissues (Grant Agency of the Ministry of Health of the Czech Republic).

220-02/01/2001 SKLÁDAL, P.: Biosensor for the detection of biological agents - Laboratory prototype for detection of tularemia - IMUNO-BBP (Czech Ministry of Defence).


MIKE�, V.: Visiting professor, Department of Phytopharmacy, INRA, Dijon, France, 1 month (Fellowship of French Ambassy).

NAVRÁTILOVÁ, I.: Visited the Department of Bioelectronics and Bioengineering, University of Genoa, Italy, January, 1 month.

SKLÁDAL, P.: Invited lecture and MEBFOOD project meeting, Moscow State University, Moscow, Russia, June 3-4, 2001.

SKLÁDAL, P.: Visited the Department of Biochemistry, National University of Ireland, Cork, Ireland, Sept. 12, 2001.

SKLÁDAL, P.: Visited the Potsdam University, Golm, Germany, - Meeting of the INTELLISENS project, November 5-6, 2001.

SKLÁDAL, P.: Visited the Department of Bioelectronics and Bioengineering, University of Genoa, Italy, November 13-14, 2001.

SKLÁDAL, P.: Visited the Institute of Pharmaceutical Research �M. Negri�, Milan, Italy, November 15-17, 2001.

SKLÁDAL, P.: Evaluation of Research Proposals, Directorate of Science, European Community, Brussels, Belgium, November 20-25, 2001.

WIMMEROVÁ, M.: Centre de Recherches sur les Macromolécules Végétales (CERMAV), Molecular Glycobiology Group, Grenoble, France, October 2001 � September 2002.


Cooperations

Chemistry Department, University California, Berkeley USA (F. �vec, Z.Glatz).

Department Chemistry, Iowa State University, Ames, USA (W. Armstrong, L. �najdrová, Z. Glatz).

Department of Analytical Biochemistry, University of Potsdam, Potsdam, Germany (A. Makower, F. Scheller, P. Skládal).

Department of Analytical Chemistry, Lund University, Sweden (J. Emneus, T. Ruzgas, P. Skládal).

Department of Bioelectronics and Bioengineering, University of Genoa, Italy (R. Raiteri, I. Navrátilová, P. Skládal).

Department of Chemistry, State University of New York, College at Potsdam, USA (M. Hepel, J. Halámek, P. Skládal).

Department of Chemical Enzymology, Moscow State University, Moscow, Russia (S. Eremin, M. Lebedev, P. Skládal).

Department of Phytopharmacy, INRA, Dijon, France (V. Mike�, supported by bilateral project Barrande).

School of Biological Sciences, University of Wales, Bangor, UK (D.B. Johnson , M. Mandl).

Foreign visitors

I. B. Arredondo, National University of Mexico, Mexico, a visit to P. Skládal, September 2000 - March 2001.

Dr. J-P. Blein, INRA, Dijon, France, a visit to V. Mike� supported by the project Barrande.

Prof. M. Hepel, State University of New York, Potsdam, USA, June 2001.

Dr. D. Kupka, Institute of Geotechnics, Slovak Academy of Sciences, Ko�ice, a visit to M. Mandl, November 2001.

Dr. A. Makower, University of Potsdam, Potsdam, Germany, September 2001.

Prof. Manuel G. Roig, University of Salamanca, Spain, visit to P. Zbořil, January 2001.

Dr. Didier Marion, Laboratory of vegetable products, INRA, Nantes, France, a visit to V. Mike� supported by French Ambassy.

Dr. M. Ponchet, INRA, Antibes, France, a visit to V. Mike� supported by the project Barrande.

Dr. Thierry Prangé, Faculty of Pharmacy, Paris, France, a visit to V. Mike� supported by the project Barrande.

Dr. T. Ruzgas, University of Lund, Sweden, a visit to P. Skládal, December 2001.

F. �vec, Chemistry Department, University California, Berkeley, USA, a visit to Z. Glatz, September 2001.

STUDENTS STUDYING ABROAD

J. HALÁMEK: Research stay at the Unviersity of Potsdam, Department of Analytical Biochemistry, Potsdam, Germany, 3 months.

J. FRIML: Max Planck Institut, Koeln, BRD (PhD studies).

T. KA�PAROVSKÝ: Unité associée Université de Bourgogne/INRA, Dijon, France, a fellowship for a 2 week stay.

J. PŘIBYL: State University of New York, Potsdam College, Potsdam, USA, fellowship for a 3-month research stay.


KUČERA. I.: Member of the Committe of the Grant Agency of the Czech Republic; Head of the Section Chemistry

MANDL, M.: Member of the Committee of the Czech Biotechnological Society; Lectures on biotechnology, Faculty of Chemistry, University of Technology, Brno.

MIKE�, V.: Member of the Committee of the Czech Society for Biochemistry and Molecular Biology; Member of the Committe of the Agency of Fund for Development of Ministry of Education.

PAVELKA, S.: Supervisor in biochemistry and pathobiochemistry, and lecturer in biochemistry: Ph.D. studies of biomedicine, Charles University and Academy of Sciences of the Czech Republic, Prague.

SKLÁDAL, P.: Member of the Scientific Committee for the COST 518 Workshop Materials for Biomedical Applications; Member of the ASCOS Planning Committee - International Courses on Optical Sensors and Biosensors.

WIMMEROVÁ, M.: Member of the Brno Branch Committee of the Czech Chemical Society; Member of the National Author Team of the Czech Chemistry Olympiad; Member of the Regional Committee of the Czech Chemistry Olympiad.

ZBOŘIL, P: Member of the Committe of the Agency of Fund for Development of Ministry of Education.

Department of Inorganic Chemistry


Teaching activities

The Department of Inorganic Chemistry provides education in the basic chemical disciplines, i.e. general and inorganic chemistry for students at the bachelor level, who major in chemistry, biology, geology and physics, as well as for chemistry teachers. Advanced inorganic chemistry lectures and courses at the master level are offered for students who major in inorganic chemistry. The Department also provides a basic course of nuclear chemistry and offers an advanced course in radioecology. A specialized laboratory course of inorganic chemistry students is offered to the students who major in inorganic chemistry.

Instrumentation

A new P1-C40P Phoenix refrigerated circulator has been purchased for X-ray structure laboratory. Temperature of its large 12 l bath can be controlled to 0.01°C in the wide range from -40° C to 150° C. The Department has a well-equipped X-ray structure laboratory. The four circle κ-axis diffractometer KUMA KM-4 has been upgraded by installing a new CCD area detector. The Oxford cryosystem device enables a routine low temperature data collection. We are capable of growing single crystals from liquids or liquefied gases and thus determine their solid state structure.

The laboratory of vibrational spectroscopy is equipped with an EQUINOX 55/S/NIR FTIR spectrometer, Bruker, which enables measurements of absorption spectra in the near (15 000-4 000 cm-1) and middle (4 000-400 cm-1) infrared regions. The spectral resolution is 0,5 cm-1. The FT Raman spectral measurements with FT-RA module FRA 106/S can be performed with a resolution of 1,5 cm-1. An air-cooled Nd:YAG laser (1064 nm, max. output 500 mW) is used for spectra excitation.

A chemical pumping unit PC 004 Vario, Vacuubrand, Germany enables vacuum distillation of corrosive or hydrolytically unstable substances at a preset constant pressure.

An inert atmosphere glove box MBraun UNILAB has been obtained as a generous gift from the Alexander von Humboldt Foundation. It allows handling of highly moisture and air sensitive materials. The inner nitrogen atmosphere of the box contains less than 1 ppm of water and oxygen.

A NMR probe head now allows measurements of heterocorrelated (1H, 13C, 19F, 31P) 2D spectra on a Bruker 300 spectrometer.

A PANAMETRICS moisture monitor series 35 with aluminium oxide humidity sensor and computer enhanced response enables quantitative monitoring of moisture traces in the inert-gas supply.

Research activities

The interactions between POF3 and some aprotic nitrogen bases were investigated by 19F and 31P NMR spectroscopy. The reaction with pyridine gave a crystalline 1:1 donor-acceptor complex py•POF3 with a novel dimeric structure of trans-py2•P2O2F6, whereas both possible stereoisomers of an 1:2 adduct py•2POF3, the cis- and trans- py•PF4OP(O)F2, were identified in the solution.

The investigation in the filed of new extraction and complexing agents - derivatives of bis(phosphoric)acids of the common formula (RO)(OH)P(O)[(OCH2CH2)3O]P(O)(OH)(OR), R = alkyl, aryl, was finished. It seems that the dodecyl derivative is the best extraction agent for Eu, Am, and Ce.

An intensive work continued on the study of reactions of chlorodithiophoshoric acid pyridiniumbetaine, PyPS2Cl, with polyfunctional nucleophile reagents. The reaction of PyPS2Cl with thiosemicarbazide derivatives (2-methyl-4-isopropyl- or 2-methyl-4-tert.-butylthiosemicarbazide) led to the formation of new five membered P-N-N-C-S heterocyclic compounds, e. i. 5-isopropylamino-4-methyl-2-sulfido-2-thioxo-1,3,4,2λ5-thiadiazaphospholan-5-onium or 5-tert.-butylamino-4-methyl-2-sulfido-2-thioxo-1,3,4,2λ5-thiadiazaphosholan-5-onium. These compounds have a three-coordinate C-atom in the cycle. Its positive charge is compensated by a negative one delocalized on the PS2-group.

In the research area of inorganic materials chemistry, we prepared a series of cage aluminophosphonates and titanosilicates as organic-soluble molecular precursors. The reactions of these molecular building units with various reagents were studied with the aim of establishing reactivity patterns of their functional groups. The functionalized molecules will be assembled via non-aqueous sol-gel routes to form three-dimensional ordered networks. Resulting materials find applications as molecular sieves, adsorbents, and selective catalysts. A new non-aqueous sol-gel route to mixed oxide materials has been developed. It allows mixing of the components at a molecular level and provides materials with a high degree of homogeneity. These products are useful refractory, optical, and electronic materials. Mesoporous metallophosphate materials were prepared by a supramolecular templating route. New gemini type surfactants were employed. Reactivity of alumazene was studied in reaction with phosphoric acid triesters, phosphonate diesters, and metal alkoxides. A novel aluminium amide-phosphate possessing an adamantane-like core was isolated and spectroscopically and structurally characterized.

The preparation and spectroscopic characterization of tellurium heteroleptic complexes the type TeLX2; X=monodentate ligand; L=bidentate ligand (substituted imidophosphinates) [Ph2P(E)-NH-P(E)Ph2], E=chalkogens have been introduced in our research activities. To extend the knowledge of the complex chemistry of this element (including structural investigations), a series of new selenium (for comparison) and tellurium compounds have been synthesized and subsequently their structures have been determined by means of X-ray crystallography.

The research in the area of oxidized imidodiphosphinates was carried on. We succeeded in the synthesis of three new chiral phosphorus ligands (one phosphorus bears electronically different groups � phenyl as well as phenoxy group), which were isolated in form of crystalline racemates. Further investigations of stereoselective synthesis of chiral P-N-P systems continue. In addition to asymmetrical P-N-P ligands of the general formula R2P(E)-NH-P(E')R'2; R, R' = iPr, Ph, PhO; E, E' = O, S, Se, the chemistry of ligands with different P-bridging group (disubstituted ferrocene, pyridine) was developed. The intention is to compare the relations of both organic substituents in R2P(E)- groups and bridging group (Fc, NH, Py, CH2 etc.) to a central core geometry of coordination compounds.

Halogenides of imido-bis(sulfuric) acid and their salts have recently attracted an attention as perspective solutes in lithium batteries. The reactions of Cl3PNSO2Cl with various nucleophilic and electrophilic reagents lead to derivatives of imido-bis(sulfuric) acid and various

polyheteroatomic molecules. One of the aims of this research is a synthesis of a genuine heterocycle containing no metal atoms. This research is performed in collaboration with the Rhodia company.

Research activities of the radiochemical section of the Department focus on the use of radioactive tracers in the study of complex equilibria in solutions and in elucidation of the chemistry of solvent extraction of selected metal ions. Recent topics included the study of solvent extraction of Eu(III) and Am(III) from aqueous-organic media, and complexation of selected metals with humic acids. The radiochemical laboratory is also engaged in the determination of radon in the environment.

DEPARTMENT STAFF

Head: Zdirad �ák (Professor, RNDr., CSc.) Professor: Jiří Hála (RNDr., CSc.) Associate Professors: Josef Novosad (RNDr., CSc.) Jiří Pinkas (RNDr., Ph.D.) Jiří Příhoda (RNDr., CSc.) Antonín Rů�ička (RNDr., CSc.) Jiří Tou�ín (RNDr., CSc.) Assistant Professors: Milan Alberti (RNDr., CSc.) Milo� Černík (RNDr., CSc.) Dalibor Dastych (RNDr., Dr.) Ale� Mareček (RNDr., CSc.) Marek Nečas (Mgr., Ph.D.) Technicians: Světlana Filípková Helena Hřibová Zdena Michaličková Jiří Smola Alena �evčíková Secretary: Vladimíra Veselská Ph.D. Students: Full time Valerie Alexová (Mgr.) Martin Beran (Mgr.) Zuzana Brlejová (Mgr.) Markéta Chromá(Mgr.) Lenka Jablonská (Mgr.) Michal Janča (Mgr.) Vojtěch Jančík (Mgr.) Luká� Richtera (Mgr.) Pavel Rovnaník (Mgr.) Radek Sluka (Mgr.) Jan Taraba (Mgr.)


Diploma theses:

Alexová, V.: The study of preparation and reactivity of hexafluro-cyclo-triphosphazene. (supervisor: M. Alberti) (in Czech).

Beran, M.: The study of preparation, structure and reactivity of 1,1´-bis(diisopropylphosphino)ferrocene. (supevisor: J. Novosad) (in Czech).

Kratochvíl, J.: Preparation of substituted phosphonic acids and synthesis of new metallophosphonate precursors. (supevisor: J. Pinkas) (in Czech).

Skácel, R.: Reactions of chlorodithiophosphoric acid pyridinium betaine with thiourea derivatives. (supervisor: J. Příhoda) (in Czech).

Valouchová, V.: Ecology in teaching of chemistry at high school (supervisor: A. Mareček) (in Czech). PhD theses: Nečas, M.: Synthesis and coordination chemistry of P-N-P(C) ligands. (supervisor: J. Novosad) (in Czech).

Novoměstská V.: Reactions of phosphoric acid derivatives with bifunctional nucleophiles. (supervisor: J. Příhoda) (in Czech) PROJECT GRANTS RECEIVED

Research Projects

CEZ: J07: 143100011 �ák, Z.: Structure, Bonding, Properties, and Analysis of Synthetic and Natural Molecular Assemblies. Grant Agency of the Czech Republic 203/01/1533

Pinkas, J.: New Nonaqueous Routes to Phosphate, Silicate, Hybrid, and Oxide Materials. Grant Agency of the Ministry of Education, Youth and Sports of the Czech Republic G4 597/2001 Pinkas J.: Preparation of Alumazene and its Reactions with s Hexafluoro-cyclo-triphosphazene.


Novosad, J.: Department of Chemistry, Cukurova University, Turkey, invited lecture Coordination chemistry of P-N-P ligands (December 2001). Pinkas, J.: Institute of Inorganic Chemistry, Göttingen University, Germany, Socrates Program, lecture series on Materials Chemistry (June 2001). Příhoda, J.: School of Technology and Economics Dresden, Germany, 1 week (September 2001). �ák, Z.: School of Technology and Economics Dresden, Germany, 1 week (September 2001).


Foreign visitors Prof. Husebye, S., University of Bergen, Norway, 1 week, lecture Synthesis and structures of some square planar tellurium(II) complexes containing bulky substituted thiourea ligands (May 2001). Prof. Andruh, M., University of Bucharest, Romania, Visiting Professor, 2 weeks, lecture series From serendipitous to rational level in the synthesis of polynuclear complexes (November 2001). Prof. Watanabe, M., Chubu University, Kasugai, Japan, three days (July 2001). Prof. Herrmann, E., School of Technology and Economics, Dresden, Germany (July 2001). Dr. Foreman, M., University of Reading, Reading, United Kingdom, (September 2001). Cooperations

University of St Andrews, Department of Chemistry, St Andrews, UK (Prof. J.D. Woollins) �Coordination Chemistry of P-N Ligands� (J. Novosad, M. Nečas).

University of Bergen, Department of Chemistry, Bergen, Norway (Prof. S. Husebye) �Studies of Structure, Coordination and Bonding in Tellurium Compounds� (J. Novosad, M. Nečas).

Chubu University, Department of Applied Chemistry, Kasugai, Japan (Prof. M. Watanabe) �Chemistry of Polyphosphates� (J. Novosad)

Kaunas University of Technology, Department of Chemical Technology, Kaunas, Lithuania (Prof. V. Janickis) �Chemistry of Polychalcogen Compounds� (J. Novosad, M. Nečas).

Department of Inorganic Chemistry, University of Göttingen, Germany, (Professor H. W. Roesky), Molecular Alumino- and Gallophosphates as Models of Zeolite Building Units and New Non-Aqueous Sol-Gel Routes to Oxide Materials (J. Pinkas). Institute of Inorganic and Analytical Chemistry, Justus-Liebig-University of Giessen, Germany, (Professor M. Fröba), New Mesoporous Aluminophosphate Materials (J. Pinkas). Department of Chemistry, University Siegen, Germany, (Professor W. Plass), Synthesis, Structure, and Properties of Vanadosilicate and -phosphate Materials (J. Pinkas). School of Technology and Economics, Dresden, Germany (Professor E. Herrmann) �Organophosphorus compounds and their complexes� (Z. �ák, J. Příhoda).

University of Wroclaw, Institute of Chemistry, Poland (Professor T.Glowiak), �Low temperature diffractometry� (Z. �ák).

University of Vienna, Institute of Inorganic Chemistry (Dr. P. Unfried) and Institute of Mineralogy and Crystallography (Dr. G. Giester), �Structures of rare earth metal compounds� (Z. �ák).

University of Vienna, Wissenschaftliche Technische Zusammenarbeit, �Program - Kontakt 1999-7�, �Synthesis, Crystal Chemistry and Properties of Lanthanoid Metal Cluster in Basic Nitrates and Paratungstates� (Z. �ák).


Rovnaník, P., Jančík, V., Richtera, L.: Institute of Inorganic Chemistry, University of Göttingen, Germany, 3 months (February-April 2001).

Brlejová, Z., Chromá, M.: Institute of Inorganic Chemistry, University of Göttingen, Germany, 3 months (October-December 2001).

Janča, M., Jablonská, L.: School of Technology and Economics, Dresden, Germany, 3 months, (October-December 2001).


Černík, M.: Member of Inorganic Chemistry Committee, Czech Chemical Society, Prague. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Hála, J.: Associate member of the Commission V.8 (Solubility) of IUPAC. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno. Member of the Nuclear Chemistry Board of Examiners for Ph.D. study, School of Nuclear

Engineering, Technical University, Prague.

Novosad, J.: Member of Inorganic Chemistry Committee, Czech Chemical Society, Prague. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Pinkas, J.: Member of the American Chemical Society. Member of the Chemistry Board, Grant Agency of the Czech Republic. Coordinator of the Socrates/Erasmus Program. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Příhoda, J.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno. Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Charles University, Prague.

Tou�ín, J.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

�ák, Z.: Member of the Inorganic Chemistry Board of Examiners for Ph.D. study, Masaryk University, Brno.

Department of Organic Chemistry


The fundamental part of the education as well as research in the field of Organic chemistry is concentrated at the Department of Organic Chemistry with its Division of Macromolecular Chemistry.

TEACHING ACTIVITIES

The Department is responsible for teaching organic chemistry and related subjects, macromolecular chemistry and related subjects and chemical technology. These disciplines are taught to students seeking bachelor�s degree in chemistry (3 years Bc), a master�s degree (5 years Mgr) as well as to students involved in teaching career in chemistry. Education is provided also for those studying biology and environmental science. The Department makes a substantial contribution to the education of all the specialists in organic, inorganic, physical and analytical chemistry, and biochemistry.

Undergraduate study

The primary focus of the Department is the education of specialists in organic and macromolecular chemistry. The usual length of study is five years and is completed with the student�s diploma thesis. The Master�s (Magister �Mgr.�) degree is conferred after successful completion of this program. The students are gaining knowledge and experience in all the theoretical and experimental chemistry disciplines including: synthesis, isolation, identification, and structural studies on chemical compounds using all the modern methods of analysis, as well as knowledge in the application of computer assisted chemistry. Diploma thesis, its defense and the state examination complete the study.

Graduate study

The Department offers a program leading to the Ph.D. degree. The program usually takes three years. The students within this program, besides studying some new chemical disciplines, are teaching undergraduate programs in laboratories and seminars and are active members of research groups having access to all the research facilities available at the Department, including NMR, UV - VIS and IR spectrometer instruments, GC, GC/MS and HPLC chromatography, microwave and ultrasound reactors, X-ray analysis and advanced computer technology. Study is completed following the successful defense of the doctoral thesis, and the final rigorous examination.

RESEARCH ORIENTATION

There are two basic orientations in research at the Department: Synthetic organic chemistry focused on heterocyclic compounds, and computer assisted organic chemistry in research of the structure and dynamic of biomolecules.

Synthetic Organic Chemistry

Heterocyclic organic chemistry

New methods of synthesis, cyclization reactions, reaction mechanisms, reactivity of the new heterocyclic systems as well as their structure are studied. There are several research groups working in this area. One of the groups is concentrated on cyclization reactions leading to heterocyclic systems. Pericyclic reactions, their regio- and stereochemistry, especially 1,3- dipolar cycloadditions of ylides derived from quaternary isoquinoline derivatives, are searched. The research effort includes a special sort of cycloadditions, so - called �criss-cross� cycloadditions and the very interesting transformations of this way prepared heterocycles. Some of the reactions, especially intramolecular varieties, are carried out under microwave initiation and searched their influence upon the reaction. Besides, the center of interest are molecules of naturally occurring quaternary isoquinoline alkaloids in reactions with nucleophiles and also their transformations are studied. Application of organometallics on preparation of new adamantane derivatives is upon investigation as well (M. Potáček, J. Dostál, M. Trávníček, J. Verner, R. Vícha, S. Man, J. Pospí�il).

The synthesis of substituted cyclic α-methylenlactones and their reactivity in vinylic nucleophilic substitution and 1,3-dipolar cycloaddition are the fields of interest of the second research group (J. Jonas, C. Mazal, P. Mel�a).

Another group (P. Pazdera, L. Richter, R. Čmelík, D. Fajkusová, and M. W. Fathalla) is interested in synthesis, structure elucidation and reactivity studies on fused five, six, seven and eight membered heterocycles containing nitrogen atom and/or the sixth group elements. Heterocyclic skeletons are prepared by an application of aromatic or heterocyclic carboxylic and carbonic acid functional derivatives and diaminomaleodinitrile, respectively. This research group is concentrated also on the preparation of new heterocyclic compounds containing chalcogene-chalcogene bond by oxidative heterocyclization reactions. In some cases are syntheses realized like domino-processes.

A number of the synthesized compounds have been tested for their biological and pesticide activity, in addition to their application as photo-components and UV light stabilizers. The spectroscopy (FTIR, UV-VIS, NMR) and X-ray analysis methods are used for the identification and structural elucidation. In some cases an application of chemical ab initio calculations is provided in cooperation with the Laboratory of Biomolecular Structure and Dynamics.

Organic Photochemistry

The research activities of the group are concentrated in several areas. One is the study of photoinduced intramolecular energy and electron transfer in partially flexible bichromophores: how the character of flexible tethers influences the transfer rate constants and mechanism of the transfer. The second area involves the study of various photochemical transformations, such as hydrogen abstraction or di-π-methane rearrangement, with a special interest in photochemical reactivity of organic compounds in aqueous solutions as well as in the solid state. The group is also involved in developing a completely new photochemical field � microwave photochemistry. (P. Klán, M. Zabadal)

NMR Spectroscopy

NMR spectroscopy of organic and bioorganic molecules is the field of interest of the NMR research group (R.Marek, O.Humpa). The research is focused on the study of alkaloids and other compounds isolated from the plants. These problems are solved in collaboration with the Faculty of Medicine (MU) and University of Antwerp, Belgium. Of course, other types of organic molecules that are the synthetic targets of the other groups are studied, too.

Computer assisted organic chemistry and molecular modeling

The research effort of the computer assisted organic chemistry group (J. Koča, M. Kratochvíl) is concentrated in three areas. The first is computer assisted organic synthesis using both topological and quantum chemistry methodology. Current attention is paid to reaction paths and transition states elucidation. The second field involves conformational studies on flexible molecules of a biological interest (pheromones, peptides, carbohydrates, nucleic acids). The third direction is focused on computer study of interactions and reactions of large biological polymers, especially proteins, with small substrates. This group has made an important contribution to information technology applications in chemistry.

Macromolecular chemistry

Another integral part of the Department of Organic Chemistry is the Division of Macromolecular Chemistry (J. Sedlář, J. Petrůj, M. Potáček and Z. Salajka, L. Pospí�il). It seems to be a significant bridge for collaboration with Polymer Institute of Brno and Faculty of Chemistry of the Technical University of Brno. The scientific interest of the Division is focused on olefin polymerization, polymer stability studies and development of photostabilizers and composite materials.

DEPARTMENT STAFF

Head: Milan Potáček (Prof., RNDr., CSc.) Professors: Jaroslav Jonas (RNDr., CSc.) Jaroslav Koča (RNDr., D.Sc.) Milan Kratochvíl (Ing., CSc.) � professor emeritus Associate Professors: Pavel Pazdera (RNDr., CSc.) Jaroslav Petrůj (RNDr., CSc.) Assistant Professors: Petr Beňovský (RNDr., Ph.D.) Slávka Janků (RNDr., Dr.) � mother holiday Petr Klán (RNDr., Ph.D.) Radek Marek (RNDr., Ph.D.) Ctibor Mazal (RNDr., CSc.) Jiří Sedlář (Ing., CSc) - part time Richard Čmelík (Mgr.) � part time Petr Kulhánek (Mgr.) - part time Stanislav Man (Mgr.) - part time Ondřej �karka (Mgr.) � part time Martin Trávníček (RNDr., Mgr.) � part time Jiří Verner (Ing.) - part time Robert Vícha (Mgr) - part time Miroslav Zabadal (Mgr.) -part time Teaching Assistant: Jitka Halvová (Ing.) Research Assistants: Otakar Humpa (RNDr.) � till March 2001 Radovan Kare� (Mgr.) Hana Navrátilová (RNDr.) Technicians: Jiří Mikulá�ek Marek Poděl Česlav Ulrich Luká� Malý � till July 2001 Secretary: Milena Urbánková Librarian: Jana Foltýnová Adjunct Lecturers: Vladimír Kysilka (RNDr., CSc.) � Pliva - Lachema, a.s., Brno Jiří Matou�ek (Prof., Ing., D.Sc.) - Chemical Faculty, Technical University, Brno Karel Picka (RNDr.) - Chemical Faculty, Technical University, Brno Jiří Pichler (Ing., CSc.) Antonín Sikora (Ing., CSc.) � Institute of Macromolecular Chemistry, Academy of Sciences, Czech Republic Tomá� Veselý (Ing., CSc.) � Chemical Faculty, Technical University, Brno Ph.D. Students: Full time Kamil Anto� (Mgr.)

Petr Barto� (Mgr.) Michal Čajan (Mgr.) Richard Čmelík (Mgr.) Dagmar Fajkusová (Mgr.) Petr Kulhánek (Mgr.) Stanislav Man (Mgr.) Petr Mel�a (Mgr.) Martin Prokop (Mgr.) Pavlína Sečkářová (Mgr.) Robert Skeřil (Mgr.) Ondřej �karka (Mgr.) Luká� Trantírek (Mgr.) Martin Trávníček (Mgr.) Jiří Verner (Ing.) Zdeněk Vytiska (Mgr.) Robert Vícha (Mgr) Mohamed Waleed Fathalla (M.Sc.) Miroslav Zabadal (Mgr.) Part time Hana Navrátilová (RNDr.) Luká� Richter (Mgr.) Michal Kovář (Ing.)


Diploma theses Mel�a, P.: α-Methylenlactones. Asymmetric 1,3-dipolar cykloadditions. (Supervisor: C. Mazal)

Sečkářová, P.: Structural analysis of benzophenanthridine and protoberberine alkaloids by NMR spectroscopy. (Supervisor: R. Marek)

Vytiska, Z.: Three component domino reactions with diaminomaleodinitrile. (Supervisor: P. Pazdera)

Anto�, K.: Polypropylene with decreased burning activity and increased resistance against UV degradation. (Supervisor: J. Tocháček)

Luzuriaga,S. E.: Preparation of polypropylene with high s vysokou pevností taveniny. (Supervisor: L. Pospí�il)

Skeřil, R.: Copolymerisation of ethylene and styrene with a help of metalocene catalytic systemes. (Supervisor: Z. Salajka)

Ph.D. theses Častulík, J., Mgr. : Studies in the Field of Simple α� Methylene-γ -lactones. (Supervisor: J. Jonas).

Divi�ová, H., Mgr.: N-(2-Cyanophenyl) chloromethane imidoylchloride and synthesis of fused quinazolines. (Supervisor: P. Pazdera).

Trantírek, Luká�., Mgr. : NMR as a tool for structural study of nucleic acids. (Supervisor: V. Sklenář).

Abstracts of conference papers and posters:

TRÁVNÍČEK, M., POTÁČEK, M. Regioselectivity and influence of chiral auxiliary bound on dipol upon enentioselectivity of 1,3-dipolar cycloaddition. XXVth Conference of Organic Chemists, Kutná Hora, Czech Rep., 14.-17.5.2001. KS 11.

POTÁČEK, M., POSPÍ�IL, J. Intramolecular 1,3-dipolar cycloaddition initiated by microwaves. 18th International Congress of Heterocyclic Chemistry. Pacifico Yokohama, Japan, 29.7. � 3.8.2001.

VÍCHA R., POTÁČEK M.: Synthesis of drug precursors based on adamantane. 30th Conference on Synthesis and Analysis of Drugs, Brno, Veterinary and Pharmaceutical University of Brno, Czech Republic, 17. � 19.9.2001. p. 119. VERNER, J., POTÁČEK, M. Preparation of substituted 5-thioxo[4,5-d]imidazole-2-one via mixed criss-cross cykloaddition. 36th Conference on Advances in organic, bioorganic and pharmaceutical chemistry, Nymburk, Czech Rep. 19. � 21.11.2001. p.773. KLÁN P., DEL FAVERO D., ANSORGOVÁ A., HOLOUBEK I. Ice Photochemistry of Chlorobenzenes. In Proceedings of EUROTRAC Symposium; P. M. Midgley, M. Reuther, M. Williams (Eds.), Springer Verlag, Heidelberg, Germany 2001. KLÁN P., KLÁNOVÁ J., HOLOUBEK I., NOSEK J. Ice as a Medium for Tranformations of Organic Pollutants. In Book of Abstracts: 9th ESP Congress, Lillehammer, Norway, 2001. ZABADAL M., KLÁN P. Aplikace 2,5-dimethylfenacyl (DMP) fotolabilní chránící skupiny. 36. Konference o organické, bioorganické a farmaceutické chemii, Nymburk, 2001. KLÁN P., ZABADAL M. Fotolabilní chránící skupiny v organické chemii. XXV. Konference organických chemiků, Kutná Hora, 2001. KLÁN P., NOSEK J., KLÁNOVÁ J., HOLOUBEK I. Photodegradation of Halophenols in Water Ice. In Book of Abstracts: SECOTOX World Congress, Krakow, Poland, 2001. KLÁN P., ZABADAL M., HEGER D., PELLICCIOLI A. P., WIRZ J. 2,5-Dimethylphenacyl Chromophore: A Photochemical Switch. Younger Chemist Meeting, Regensburg Germany, 2001. CÍRKVA V., KLÁN P., HÁJEK M. The Microwave Photochemical Reactor for Synthesis. 8th International Conference on Microwave and High Frequency Heating, Bayreuth, Germany, 2001.

RŮ�IČKA R., KLÁN P., ZABADAL M. Fotochemické aplikace katalýzy fázového přenosu. XXV. Konference organických chemiků, Kutná Hora, 2001. HOLOUBEK I., KLÁN P., ANSORGOVÁ A., DEL FAVERO D. The Photochemistry of PBT Compounds in the Ice. SETAC, Madrid 2001. BEŇOVSKÝ P., STILLE J.R. Příprava analogů isochinolinových alkaloidů pomocí aza-annulační reakce. XXV. Konference organických chemiků, Kutná Hora, 2001, Czech Rep., 14.-17.5.2001. KS 02. BEŇOVSKÝ P. Stereoselektivní aza-anulační reakce. 36. Konference Pokroky v organické, bioorganické a farmaceutické chemii, Nymburk, 2001, Czech Rep., 19.-21.11 2001. ČAJAN M., LHOTÁK P., KOČA J., STIBOR I. Konformační chování thiacalix[4]arenů, 36 konference �Pokrokyv organické, bioorganické a farmaceutické chemii� Nymburk, Czech Republic, 19. � 21. 11. 2001, Chemické listy č. 11. Major popularisations and other professional publications: POTÁČEK, M.: Cena za chemii opět na Masarykově univerzitě, (Prize for Chemistry again at Masaryk University), Univerzitní noviny, vol.1, 2001, p.14.

POTÁČEK, M., WORGOTTER, Z.: Dr. Alfred Bader opět na Masarykově univerzitě � tentokrát s novým návrhem, (Dr. Alfred Bader again at Masaryk University � this time with a new proposal), Univerzitní noviny, vol.7 - 8, 2001, p.19.

POTÁČEK, M.: Ceny za chemii, ( Prize for Chemistry), Univerzitní noviny, vol.7 - 8, 2001, p.36.

PAZDERA, P.: 38 th Chemical Olympiad, Organic Chemistry Part, Contest Problems and Their Solutions for Schools, Regional and National-Wide Levels in the Categories A and E, Institute of Children and Youth, Ministry of Education, Czech Republic.


Grant Agency of Ministry of Education FRV� 555/2001 Potáček, M., Kulhánek, P., Vícha, R. � Inovace způsobu přípravy studentů k laboratornímu cvičení z organické chemie (Inovation of students preparation to laboratory exercises in organic chemistry).

592/2001 Man, S., Potáček, M. � Criss � cross cykloadiční reakce allenů s aziny (Criss � cross cycloaddition reactions of allenes with azines). COST D 10.20. Potáček, M.: Microwave Activation in Organic Transformations. 0587/2001 Klán P., Rů�ička R. - Vyu�ití katalýzy fázového přenosu ve fotochemii (Phase-transfer catalysis in photochemistry). VaV/340/1/01 Holoubek I., Klán P. - Fotochemie organických polutantů ve voskové vrstvě na povrchu jehlic (Photochemistry of organic pollutants on plant needle surface). Grant Agency of the Czech Republic 201/98/KO41 Koča, J. - 1998-2003: HCI LAB - Laboratory of Man-Machine Interactions.

203/01/1333 Pazdera, P. � 2001-2004: Chalcogenorganic Compounds � Preparation, Transformation and Structure.

203/00/1011

Koča, J. � 2000-2002: Amidic ligands - design synthesis and complexes with anions (PI:Stibor, I., Institute of Chemical Technology, Prague).

Grant Agency of the Ministry of Industry and Trade MPO ČR PZ � Ch / 25 / 2001 Potáček, M.: New Way of Pharmaceutical Intermediates Preparation Based on Adamantane Derivatives.

Other grant agencies Klán, P.: The Foundation for a Civil Society award (through the generosity of Alfred and Isabel Bader).

NILU-49/2001 Klán P., Holoubek I.: Phototransformation of organic pollutants in Svalbard, Norway� Norwegian Institute for Air Research; Ny-Ålesund LSF.


Potáček, M.: Member of the Scientific Committee - 9th Blue Danube Symposium on Heterocyclic Chemistry, June 16 - 20, 2002. Tatranská

Lomnica, Slovakia.

Potáček, M.: Member of the Organizing Committee � The joint Meeting of the Czech and Slovak Chemical Society, June 30 � July 4, 20002, Brno, Czech Republic

Koča, J.: President of the Organizing Committee � The joint Meeting of the Czech and Slovak Chemical Society, June 30 � July 4, 2002, Brno, Czech Republic

Marek, R.: Member of the Organizing Committee � 16th NMR Valtice Meeting of the Central European NMR Discussion Groups, April 23 � 25, 2001, Valtice, Czech Republic.

Marek, R.: Member of the Organizing Committee � The joint Meeting of the Czech and Slovak Chemical Society, June 30 � July 4, 2002, Brno, Czech Republic

Marek, R.: Member of the Organizing Committee - 3rd Central European NMR Meeting & Bruker NMR Users Meeting,September 17 � 18, 2001, Brno, Czech Republic

Klán, P. : Secretary of the Organizing Committee � The joint Meeting of the Czech and Slovak Chemical Society, June 30 � July 4, 2002, Brno, Czech Republic

Mazal, M.: Member of the Organizing Committee � The joint Meeting of the Czech and Slovak Chemical Society, June 30 � July 4, 2002, Brno, Czech Republic


Invited Lectures

Koča, J.: Computer assisted molecular modelling in connection with biomolecules. 30th Conference on Synthesis and Analysis of Drugs, Brno, Veterinary and Pharmaceutical University of Brno, Czech Republic, 17. � 19.9.2001.

Koča, J.: Počítačové simulace proteinů-lesk a bída silových polí. 7. seminář Fyzika a chemie molekulárních systémů. VUT, Brno, Czech Republic, 2001.

Pazdera, P.: Esters and nitriles of 2-(3-Acylselenoureido)benzoic and -thiophene-3-carboxylic acids, Institute of Organic Chemistry,

University of Regensburg (Germany).


Lectures

Kent S. Gates, Ass. Professor, University of Missouri, USA, lecture: The Chemical Mechanisms of DNA Damage by the Antitumor Antibiotic Leinamycin

Prof. Dr. Andrej Petrič, University of Ljubljana, Slovenia, lecture: Synthesis, Characterization and Application of Novel Probes for Medical Research.

Prof. Dr. Robert Glaser, Ben-Gurion University of the Negev, Beer-Sheva, Israel, lecture: Polymorphism Problems in Pharmaceuticals and Solid-State CPMAS NMR. Spectroscopic/X-ray crystallographic Studies on Conformationally Mobile Molecules.

Dr. Alfred Bader, A Holder of Masaryk University of Brno Honorary Doctorate, USA, lecture: The History of the Aldrich Chemical Company + lecture: R.Anschütz, A.S. Couper and J. Loschmidt: A Detective at Work..

Prof. Dr. Slovenko Polanc, University of Ljubljana, Slovenia, lecture: New and Convenient Reagents Derived from Hydrazides.

Prof. Dr. Rajive Gupta, University of Jammu, Kashmir, India, lecture: Labscale Reactions in Domestic Microwave Oven.

Prof. Dr. Burkhard König, University of Regensburg, Germany, lecture: Fun and tension with strained alkynes. Synthesis, structure and properties of functionalized enediynes.

Cooperation

Prof. Dr. Albrecht Mannschreck, Institut für Organische Chemie, Universität Regensburg, Germany, Enantiomeric separations. (M. Potáček, P. Pazdera).

Dr. André Loupy, Université Paris � Sud, Institut de Chemie Moleculaire d�Orsay, Laboratoire des Reactions sur Supports, France. Microwave Assisted Organic Synthesis (M. Potáček, P. Klán).

Dr. Lajos Kovács, University of Szeged, Hungary, N7/N9 � Guanine Derivatives (R. Marek).

Prof. Dr. Wolf-Diethard Pfeiffer, Institut für Chemie, Universität Greifswald, Germany, Synthesis of Organic Selenium Compounds (P. Pazdera).

Prof. Dr. Peter Kutschy and Prof. Dr. Milan Dzurilla, Department of Chemistry, P. J. �afárik University, Ko�ice, Slovak Republic, Synthesis of phytoalexin analogues (P. Pazdera).

Prof. Josef Michl, University of Colorado, Boulder, CO, U.S.A., Synthesis of bicyclo[1.1.1]pentane derivatives (C. Mazal).

Prof. Dr. Jacek Mlochowski, Institute of Organic Chemistry, Biochemistry and Biotechnology, Wroclaw University of Technology, Synthesis of 2-Aminoselenophenole and its Synthetic Applications (P. Pazdera).

Prof. Jakob Wirz, Institut für Physikalische Chemie, Switzerland: Laser flash photolysis of phenacyl chromophores (P. Klán). CERMA V Grenoble, France (J. Koča): Structural studies in carbohydrate chemistry.


Dominik Heger, Université Paris � Sud, Institut de Chemie Moleculaire d�Orsay, Laboratoire des Reactions sur Supports, France � 3 months.

Jaromír Literák, Université Paris � Sud, Institut de Chemie Moleculaire d�Orsay, Laboratoire des Reactions sur Supports, France � 3 months.

Jiří Pospí�il, Université Catolique Louvain-la-Neuve, Laboratoire de Chimie Organique, Belgium � 3 months.

Richard Čmelík, Mgr., Universität Regensburg, Institut für Organische Chemie, Germany � 3 months.

Robert Vícha, Mgr., Universität Regensburg, Institut für Organische Chemie, Germany � 3 months.

Dagmar Fajkusová, Mgr., Universität Regensburg, Institut für Organische Chemie, Germany � 3 months.

Robert Skeřil, Mgr., University of Bristol, School of Chemistry, Great Britain � 3 months.

Dominik Heger, University of Missouri, USA - 2 months.

Jaromír Literák, University of Missouri, USA- 2 months.

Jiří Pospí�il, University of Missouri, USA- 2 months.

FOREIGN STUDENTS STUDYING AT THE DEPARTMENT

Jana Záletová, Mgr., Department of Organic Chemistry, P. J. �afárik University, Ko�ice, Slovak Republic, Syntheses of Compounds with Indol-3-yl Benzothiazole Skeleton � 3 months (Joint project: supervisors: P. Pazdera and M. Dzurilla).

STUDENT AWARD

Mgr. Jakub Častulík � Masaryk University Rector Award


Potáček, M.: Chairman: Chemical Section Scientific Board and Organic Chemistry Scientific Board at Masaryk University, Chairman of the Commission for State Examinations at MU in Organic Chemistry, Member of Organic Chemistry Scientific Board at Charles University of Prague, Prague Institute of Technology and Palacky University of Olomouc, Member of the State Examination Committee at Prague Institute of Technology, Palacky University Olomouc, University of Pardubice and Technical University of Brno, Faculty of Chemistry, Fellow of The Royal Society of Chemistry, London.

Koča, J.: Member of the Scientific Board at Faculty of Science and Faculty of Informatics, Masaryk University of Brno, Chairman of The Czech Chemical Society - Brno Branch, Member of The American Chemical Society, member of the government accreditation board in chemistry.

Pazdera, P.: Member of Commission for Defence of Ph.D. Thesis, Department of Organic Chemistry, Slovak Technical University, Bratislava, Slovak Republic, Member of Habilitation Commission, Faculty of Chemistry, University of Pardubice, Member of Organic Chemistry Scientific Board and State Examination Commission at Masaryk University.

Cooperation with Industry

Syntheses of the chosen side products formed during the preparation of pharmaca. Pliva - Lachema, Brno (M. Potáček, P. Pazdera).

Department of Theoretical and Physical Chemistry


The Department of Theoretical and Physical Chemistry at the Faculty of Science continued to contribute substantially to the education of future chemists in the field of physical chemistry (about 60 students per year), future teachers of chemistry (about 30 students per year), future biologists and ecologists (about 60 students per year) as well as to research activity in the fields of theoretical and physical chemistry.

These efforts involved fundamental lectures on physical chemistry, quantum chemistry, chemical constitution and specialized courses in electrochemistry, chemical kinetics, quantum chemistry, spectroscopy (NMR, EPR, MS), phase equilibria, statistical thermodynamics and irreversible processes including extensive laboratory courses at undergraduate and postgraduate levels. The research activity of the department concerned the study of the chemical and electrochemical reactivity of chemical substances and the relation to their structure through the use of different experimental and theoretical methods of physical chemistry. Reactions provided by electron transfer have been studied by means of electrochemical methods. New method of electrochemical signal processing and electrochemical methods with simultaneous membrane introduction mass spectrometry and with simultaneous electron paramagnetic resonance have been designed. Phase equilibrium studies in metallic systems have been performed in collaboration with the Institute of Physics of Materials, Academy of Sciences of the Czech Republic, electrochemistry of nucleic acids and proteins are performed in collaboration with the Institute of Biophysics, Academy of Sciences of the Czech Republic. The spatial structure of biological macromolecules and biomacromolecular dynamics is studied by means of high field NMR in solutions. In addition this department studies other physico-chemical properties of molecules (surface tension, viscosity, conductivity, etc.) in relation to their molecular structure using computer simulations and molecular modelling.

DEPARTMENT STAFF

Head: Jan Vře�ťál (Prof., RNDr., D.Sc.) Professors: Miroslav Holík (RNDr., CSc.) Vladimír Sklenář (RNDr., D.Sc.) Associate Professors: Pavel Janderka (RNDr., CSc.) Pavel Kubáček (RNDr., CSc.) Marie Studničková (RNDr., CSc.) Libu�e Trnková (RNDr., CSc.) Assistant Professors: Pavel Bro� (RNDr., Ph.D.) Jiří Sopou�ek (RNDr., CSc.) Jaromír Tou�ek (Mgr., Dr.) Technicians: Franti�ek Macourek Dana Tesařová Secretary: Marta Holíková Adjunct Lecturers: Michal Roth (Assoc. Prof., RNDr., CSc.), Inst. Anal. Chem. Acad. Sci. CR Brno Jiří Čermák (RNDr., CSc.) Inst. of Physics of Materials Acad.Sci. CR Brno Ph.D. Students: Full time Iveta Bártová (Mgr.) Eva Drbálková (Mgr.) Klára Hladečková (Mgr.) Jana Houserová (Mgr.) Radka Chaloupková (Mgr.) Libor Kapička (Mgr.) Jan Kmuníček (Mgr.) Hana Kří�ová (Mgr.) Karel Kubíček (Mgr.) Barbora Láňová (Mgr.) Eva Lichnerová (Ing.) Radim Picha (Mgr.) Richard �tefl (Mgr.) Radka Vařeková (Mgr.) Martin Zeman (Mgr.) Part time Jan Juřík (Mgr.) Petr Kovařík (Mgr.) Luká� Králík (Ing.) Markéta Munzarová (Mgr.) Petr Padrta (Mgr.) Vladimír Proks (Mgr.) Věra Rothová (RNDr.) Oldřich �ivný (Mgr.)


Diploma theses:

Abrmanová, G.: Polarographic study of structure and properties of ureasye (supervisor: M.Studničková) (in Czech) Bártová, I.: Elektrooxidation of alkaloides and flavonoides and their antioxidation activity (supervisor: M.Studničková) (in Czech) Holub, P.: Calculation of hyperfine splitting constants of beta-protons in EPR-spectra of substituted pyrrole cation radicals (supervisor: P.Kubáček) (in Czech) Chaloupková, R.: Study of kinetics of decomposition reactions of benzenediazonium salts (supervisor: P.Janderka) (in Czech) Kří�ová, H.: Internal dynamics of MUP-I as studied by the isotope-assisted NMR spectroscopy (supervisor: V.Sklenář) (in English) Kubíček, K.: Application of residual dipolar interactions for structure determination of biomolecules (supervisor: V.Sklenář) (in English) Láňová, B.: Study of reaction kinetics by mass spectrometry (supervisor: J.Vře�ťál) (in Czech) Ph.D.theses:

�tefl, R.: Dynamics of selected nucleic acid motifs by molecular dynamics (supervisor: V.Sklenář) (in English) LIST OF PUBLICATIONS

Textbooks: VŘE�ŤÁL, J., ed.: Seminar on Thermodynamics of Materials Proceedings. Brno, Masaryk University, 2001, 90 p. ISBN 80-210-2702-9. Major popularisations and other professional publications: TRNKOVÁ, L., WIMMEROVÁ, M., KIZEK, R.: 5th Workshop of Biochemists and Molecular Biologists, Newspaper of Masaryk University, Brno, MU and Foundation Universitas Masarykiana, 5, p. 25. ISSN 1211-6866, 2001. VŘE�ŤÁL, J.: Advances in Thermodynamics of Metallic Solutions. Information Bulletin of Metal Science Society 2/2001, MSS Prague, p. 5-6. PROJECT GRANTS RECEIVED

Grant Agency of the Czech Republic 106/00/0174 Vře�ťál, J. (co-ordinator Kroupa, A., IPM AS CR Brno):Thermodynamics of equilibrium states and kinetics of phase transformations in the transition metals systems with N and C. 106/99/1176 Bro� , P., Sopou�ek J. (co-ordinator Bur�ík, J., IPM AS CR Brno): Ni-based superalloys with protective coatings: microstructural assessment and thermodynamic modelling. 204/97/K084 Trnková, L. (co-ordinator Paleček, E., Institute of Biophysics, AS CR): Electrodes modified with nucleic acids and proteins. New tools in biochemical and biomedical research ( 1997-2001).

106/00/0855

Sopou�ek, J. (co-ordinator Foret, R., FSI VUT Brno): Kinetics of Carbide Precipitation in Cr-Mo Steels

203/00/0511 Sklenář, V.: Dynamics and Thermodynamics of Mouse Pheromone - Protein Complexes. Grant Agency of the Ministry of Education, Youth and Sports COST OC.P3/90 (G 0336). Vře�ťál, J.: Energetics of sigma-phase formation in transition metals systems.

KONTAKT TSR-004-99,ME 360 (G0337) Vře�ťál, J.: Differential Electrochemical Mass Spectrometry (DEMS) of Aromatic Compounds. KONTAKT ME 428 (G0395) Vře�ťál, J.: Development of new evaluation methods in chemistry. CEEPUS SK 102 (G0335) Vře�ťál, J.: F 0562/2001 (G0380) Trnková, L.: Modernization of Education in Biophysical Chemistry.

F0561/2001 (G0382) Trnková, L.: Innovation and Modernization of Special Laboratory in Physical Chemistry. F0611/2001 (G0384) Zeman, M.: Acceptor-donor interactions on the semiconductor-liquid interface during catalysis. F0607/2001 (G0385) Trnková, L., Faltýsková, E., Soukeníková, N.: Electochemical Study of Azido Compounds. F0573/2001 G0394) Drbálková, E. and Janderka, P.: Study of electochemical breaking of carbon-halogen bond. CONFERENCES (SYMPOSIA, SEMINARS) ORGANIZED BY THE DEPARTMENT

16th NMR Valtice, Meeting of the Central European NMR Discussion Groups. 23.-25.4. 2001, Valtice, CR, Holík M. - Chairman of the Organizing Committee. 5th Workshop of Biochemists and Molecular Biologists. 14.2.2001, Brno, CR, R. Kizek, L.Trnková, M.Wimmerová- Organizing Committee.

Seminar on Thermodynamics of Materials, Meeting of Central European Phase Diagram and Thermodynamics Committee. 19.11.2001, Brno, CR, Vře�ťál, J. � Chairman of the Organizing Committee.


Holík, M.: Quantitative Structure-Activity Relationship, Nankai University Tian-jin, China, 11.-18.7.2001. Janderka, P.: University Bonn, Bonn, Germany, 15.-27.10.2001. Janderka, P.: Use of On-line Mass Spectrometry in Electrochemistry, STU Bratislava, Slovak. Republic, 18.-27.6.2001. Janderka, P.: Computers in Chemistry, Nankai University Tian-jin, China, 11.-18.7.2001. Trnková, L.: Elimination Methods � Elimination Polarography and Elimination Voltammetry, Davis, University of California, USA, 12.11.-29.11.2001. Vře�ťál, J.: Ab initio Calculations Results in Phase Diagram Calculations. Inst. of Physicel Chemistry University of Vienna, Vienna, Austria, 12.6.2001. Vře�ťál, J.: Mass Spectra in Experiment and in Spectral Library. Nankai University Tian-jin, Tian-jin, P. R. China, 11.-18.7.2001. OTHER INTERNATIONAL CONTACTS AND CO-OPERATION OF STAFF Foreign visitors

Prof. R. W. Fawcett, University of California, Davis, USA , 4 days stay, lecture. Thomas Loefler, University Bonn, Bonn, Germany, 2 weeks, study stay, lecture. Prof. Dr. Raimund Podloucký, Inst. of Physical Chemistry University of Vienna, Austria, 1 day, lecture. Dr. Ing. Andrey Prikhodovsky, Research Center Jülich GmbH, Institute for Materials and Processes in Energy Systems, Germany, 5 days stay (GA ČR 106/00/0855), lecture. Prof. Ing.Andrej Sta�ko, STU Bratislava, Slovak Republic, 12 days stay (CEEPUS), lecture. Christian Gödl, Institute of Theoretical and Physical Chemistry, University Graz, Austria, 1 month, study stay (CEEPUS). Kerstin Hillmayer, Institute of Theoretical and Physical Chemistry, University Graz, Austria, 1 month, study stay (CEEPUS). Boriana Bedjova, Department of Chemistry, Sofia University, Bulgaria, 2 month, study stay (CEEPUS). Cooperation

Collaboration with the Institut of Theoretical and Physical Chemistry, University Bonn, Germany, prof.H.Baltruschat (P.Janderka, J.Vře�ťál).

Collaboration with Nankai University Tianjin, China, prof. Lin, Shao-fan (J.Vře�ťál, P.Janderka, M.Holík).

Collaboration with the Department of Physical Chemistry, Davis, University of California, USA, prof. R.W. Fawcett (L.Trnková).


Drbálková, E.: University Bonn, Bonn, Germany, 2 weeks.

Kapička,L.: Georg-August University of Göttingen, Göttingen, Germany (Sokrates), 3 months.


Holík, M.: Member of the Czech Committee for Chemistry-national associate organization to IUPAC, Chairman of the Discussion Group Magnetic Resonance Spectroscopy, Secretary of the Brno Branch of the Czech Chemical Society, Member of the Central Committee of the Czech Chemical Society, Member of the German Chemical Socienty, Member of the Physical Chemistry Board for Ph.D.studies, Palacký University, Olomouc, Member of the Physical Chemistry Board for Ph.D.studies, Faculty of Chemistry, Technical University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno,. Member of the Organic Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Janderka, P.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Kubáček, P.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Sklenář, V.: Member of the Editorial Board of the Journal of Magnetic Resonance Academic Press San Diego, USA, Member of the New York Academy of Sciences, Member of the Council of the Society International Society of Magnetic Resonance, Member Groupement Ampere, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno, Member of the Scientific Council, Faculty of Science, Masaryk University, Brno, Member of the Scientific Council, Masaryk University, Brno, Member of the Scientific Council, Charles University, Prague.

Sopou�ek,J.: External supervisor (Vít, J.: Kinetics of Carbide Precipitation in Heatresisting Steels).

Studničková, M.: Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno.

Vře�ťál, J.: Member of Scientific Board of Institute of Physics of Materials Academy of Sciences of the Czech Republic, Brno, Member of Scientific Board Faculty of Science Palacký University Olomouc and Chemical Faculty of Technical University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Masaryk University, Brno, Member of the Physical Chemistry Board for Ph.D.studies, Palacký University, Olomouc, Member of the Physical Chemistry Board for Ph.D.studies, Technical University, Brno.

RECETOX Research Center for Environmental Chemistry and Ecotoxicology


RECETOX (Research Centre for Environmental Chemistry and EcoTOXicology) was established in July 7, 1994. The Centre was a research unit of the Department of Environmental Chemistry and Ecotoxicology. In 2001, RECETOX merged with the Department of Environmental Chemistry and Ecotoxicology and, since, provides master and postgraduate studies in the fields of environmental protection, ecotoxicology and environmental chemistry. At present, RECETOX is an interdisciplinary, inter-institutional research and teaching centre working in the field of fundamental research in the environmental chemistry, ecotoxicology and risk analysis, as well as with the training of bachelor, master and postgraduate students in the fields of environmental chemistry and ecotoxicology.

Centre is not setting a goal to be a large research workplace or institute of classical type but it is based on the philosophy of relatively smaller groups of co-workers and ad hoc research teams of specialists from all the Europe formed to solve problems, grants, and orders from industry etc. External co-workers of the Centre take significant part on education in both master and doctoral studies.

The fundamental goal of RECETOX is to participate in joint research projects with European institutes and to establish creative scientific teams from various countries for the solution of environmental problems. Structure of RECETOX is as follows: Division of Environmental Chemistry (Head: Ivan Holoubek), Ecotoxicology Division (Head: Ladislav Du�ek), Environmental Analytical Chemistry Division (Head: Ale� Hrdlička), Risk Analysis and Data Evaluation (Head: Ladislav Du�ek). RECETOX staff consists of members of the Faculty of Science and outside participants from the Czech Republic and other countries. Research activities of RECETOX are based on the basic philosophy of Project TOCOEN (TOxic COmpounds in the ENvironment) and are focused on the following research topics: environmental fate and long-range transport of persistent organic pollutants, research and development of new ecotoxicological tests and methods, methodology of environmental and ecological risk assessment, mathematical modelling of the fate of pollutants, regionally�specific ecological risk assessment activities based on available multivariate environmental data, development of effective biomonitoring of stressed soils in Czech Republic, development of a novel type of software for environmental science based on expert-system built over interactive database.

The original objective of TOCOEN Project was extended to cover heavy metals, natural toxins and Persistent, Bioaccumulative and Toxic pollutants (PBTs). The acronym TOCOEN is now interpreted as "TOxic COmpounds in the ENvironment" and projects are concerned with persistent toxic substances (PTS). Currently, the main goal of TOCOEN Project is the study of relations between the concentration levels of pollutants in the environment and their potential effects to living organisms. Additionally, risk assessment and the fate of selected organic pollutants in the environment is studied in details. This includes inputs of these pollutants to various parts of environment (through emissions), their transport in compartments and between them, their transformations (photochemical, chemical, thermal, biochemical), their biological effects (dose exposure analysis), modelling of the processes, and risk assessment, management and prognosis of contamination development.

Certain groups of PTS such as polycyclic aromatic hydrocarbons (PAHs), chlorinated pesticides (Cl-PEST), polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) were selected as model compounds at the beginning of the project. Currently, other groups of organics such as chlorinated benzenes, phenols, certain other types of pesticides, chlorinated aliphatic hydrocarbons and other chlorinated aromatic compounds are also being intensively studied. All the model compounds are studied in all environmental compertments.

From 1997, cooperating research groups of the RECETOX team, TOCOEN, Ltd., and several other Czech and international institutions use for their common presentations the acronym RECETOX - TOCOEN & Associates (R - T & A).

Present activities of R - T & A group are focused on the establishment a Scientific Network on Persistent, Bioaccumulative and Toxic Chemicals (PBTs). The main goal of this Network is to bring together scientists working in this field and to explore the potential of an organised and coordinated research programme on persistent, bioaccumulative and toxic chemicals at a European level. This scientific network aims to provide a platform for scientists working in the field of environmental chemistry, environmental toxicology, ecotoxicology and risk analysis.

DEPARTENT STAFF

Head: Ivan Holoubek (Prof., RNDr., CSc.) Associate Professors: Ale� Hrdlička (Doc., RNDr., CSc.) Blahoslav Mar�álek (Doc., Ing., CSc.) - part time Assistant Professors: Ladislav Du�ek (Mgr.,Dr.) Luděk Bláha (Mgr., Ph.D.) Jakub Hofman (Mgr.) Research Assistants: Alena Ansorgová (RNDr.) Technicians: Iva Poláková (Mgr.) Secretary: Hana Kordačová Adjunct Lecturers: Jiřina Hofmanová (Doc., RNDr., CSc.) - Institute of Biophysics, Academy of Sciences CR, Brno Anton Kočan (Ing., CSc.) - Institute of Preventive and Clinical Medicine, Bratislava, Slovakia Alois Kozubík (Doc., RNDr., CSc.) - Institute of Biophysics, Academy of Sciences CR, Brno Miroslav Machala (RNDr., CSc.) - Veterinary Research Institute, Brno Petr Anděl (RNDr., CSc.) - Evernia Ltd., Liberec Ph.D. Students:

Full time Michal Boháč (Mgr.) Lucie Cicvárková (Ing.) David del Favero (Mgr.) Ludvík Dole�al (Mgr.) Jindři�ka Dolinová (Mgr.) Alan Gavel (Mgr.) Jakub Gregor (Mgr.) Jakub Hofman (Mgr.) Andrea Jesenská (Mgr.) Daniel Klime� (Mgr.) Eva Kmentová (Mgr.) Petra Kosubová (Mgr.) Ivana Marková (Mgr.) Kateřina Minksová (Mgr.) Petr Pavli� (Mgr.) Martina Pavlová (Mgr.) Martina Plí�ková (Mgr.) Zbyněk Prokop (Mgr.) Michal �karek (Mgr.) Roman �míd (Mgr.) Vendula Zlevorová (Mgr.) Part time Alena Ansorgová (RNDr.), Masaryk University, Brno Miroslav Ciganek (RNDr.), Veterinary Research Institute, Brno Jana Klánová (RNDr.), TOCOEN, s.r.o Stanislav Malý (Mgr.), ÚKZUZ, Brno Vladimír Podborský (RNDr.) Military Research Institute, Brno Marie Skybová (RNDr.), EKOTOXA Ltd., Opava Pavla Sýkorová (RNDr.), Palacky University, Oloumouc Helena Zahradníčková (RNDr.), Institute of entomology, Academy of Sciences CR, České Budějovice


Diploma theses: Gavel, A.: Applications of toxicity tests in evaluation of bioavailability of soil contaminants (supervisor: P. Čupr) (in Czech)

Gregor, J.: ATP-TOX system and its applications in the solid phase toxicity testing (supervisor: P. Čupr) (in Czech)

Ka�ný, M.: Larvae of helminths under environmental stress (supervisor: B. Koubková) (in Czech)

Machálková, K.: Methodological standardization of kinetic tests of substrate induced respiration in contaminated soils (supervisor: L. Du�ek) (in Czech)

Marvanová, S.: Biochemical characterization of mutant haloalkane dehalogenases (supervisor: J. Damborský) (in Czech)

Ma�ková, M.: Analyses of pyrethroid pesticides in environmental samples (supervisor: A. Ansorgová) (in Czech)

Ottová, E.: Effects of pollutants on life cycle of selected helminths (supervisor: B. Koubková) (in Czech)

Pavli�, P.: Contribution to the data managment of projects on ecological and human risks (supervisor: L. Du�ek) (in Czech)

Plí�ková, M.: Phytotoxicity of cyanobacteria (supervisor: B. Mar�álek) (in Czech)

�karek, M.: Bacterial tests of genotoxicity (supervisor: P. Čupr) (in Czech)

Vokounová, �.: Studies of volatilization of organochlorine contaminants from soils (supervisor: I. Holoubek) (in Czech)

Zonyga, J.: Computer aided health risk assessment (supervisor: I. Holoubek) (in Czech)

Ph.D. theses: Prokop, Z.: Bioavailability of Soil and Sediment Contaminants (supervisor: I. Holoubek)


UNEP Chemicals/GEF Holoubek, I. (Regional co-ordinator for Europe): UNEP Chemicals/GEF Project Regionally Based Assessment of Persistent Toxic Substances UNIDO/GEF Holoubek, I.: UNIDO/GEF Enabling activities to facilitate early action in the implementation of the Stockholm Convention on Persistent Organic Pollutants (POPs Convention) in Czech Republic Grant Agency of the Czech Republic 525/00/D101 Bláha, L.: In vitro methods for studies of epigenetic toxicity of xenobiotics

Grant Agency of the Ministry of Education, Youth and Sport CEZJ 0714 0003 Holoubek, I.: Environment, Carcinogenesis, Oncology FRVS 547/2001 Holoubek, I., Hofman, J., Prokop, Z.: Introduction of the identification system BIOLOG into the education of Ecotoxicology

Governmental Council for Science and Research CR / Ministry of the Environment CR VaV/340/1/00 Holoubek, I.: Region specific approaches in the analysis of ecological risks � methodology of assessment in the relationships to the natural catastrophes VaV/340/1/01 Holoubek, I.: Effects of environmental pollution to the contanination and quality of biotic components of ecosystems. Subproject: Fotochemistry of organic polutants in wax layer from the needles surfaces VaV/740/2/01 Holoubek, I.: Transformations of atmospheric pollutants in the relationships to the negative anthropogenic processes, their effects on human population, landscape receptors and modelling of atmospheric transport VaV/740/5/00 Holoubek, I.: Evaluation of ecosystem and health risks of heavy metals and persistent organic pollutants in the relationships to the obligations of CR from Convention CLRTAP

Other grant agencies Polar Programme of Norway: I. Holoubek, P. Klán: Polar Programme, Expedition Svalbarg - The Photochemistry of PBT Compounds in Ice 5th EU RTD framework programme - kontrakt EVK1-CT-1999-0001 Bláha, L. (co-operation): "BIOFILMS" - Natural Biofilms as Hightech Conditioners for Drinking Water


5th Conference "AIR 2001" Brno, Czech Republic, 14.-16.5.2001. (I. Holoubek - chairman of the organizing committee, other department staff - co-organizers)

1st Meeting of Regional Team of UNEP Chemicals/GEF Project Regionally Based Assessment of Persistent Toxic Substances, Brno, Czech Republic, 4.-8.4.2001 (I. Holoubek - Regional Co-ordinator for Europe and chairman of Meeting, other department staff - co-organizers)

1st Technical Workshop on Sources and Environmental Levels of Persistent Toxic Substances. UNEP Chemicals/GEF Project Regionally Based Assessment of Persistent Toxic Substances, Brussels, Belgium, 4.-8.12.2001 (I. Holoubek - Regional Co-ordinator for Europe and chairman of Workshop, other department staff - co-organizers)


DU�EK, L et al. Analyses of results of medical treatment in oncology - examples of real data; specifities and limitations (in Czech) XXV. Brno Oncology Days, Brno, Czech Rep., 30.5.-1.6.2001 (invited lecture)

DU�EK, L et al. Possibilities of data analyses - from measured tumor marker to clinically useful predictor (in Czech) Analytical Cytometry I, Brno, Czech Rep., 3.-5.6.2001 (invited lecture)

HOLOUBEK, I. et al. Hexachlorocyclohexanes in the Central and Eastern European countries in the comparison with other part of the world � the results from European measurement amd modelling programmes. 6th International HCH and pesticides Forum, Poznaň, Poland, 20-22 March, 2001 (invited lecture)

HOLOUBEK, I. Project IDRIS: Identifying ecological risks in the Czech Republic, an expert system approach for ecological risk assessment. Environmental Risk Colloqium: Risk-Based Strategies for Environmental Decesions. Argonne National Laboratory, Chicago, IL, USA. 29 March 2001 (invited lecture)

HOLOUBEK, I. The problem of POPs contamination in CEE countries: from global convention to regional solutions. ICS-UNIDO Expert Group Meeting on Remediation of Polluted Sites in CEE Countries: Current Status and Perspectives. Trieste, Italy, 4. - 6. 7. 2001 (invited lecture)

HOLOUBEK, I. UNEP GEF Project Regionally-Based Assessment of Persistent Toxic Substances. Zweites UBA-Fachgesprach �Persistenz und Ferntransport von POP-Stoffen�, UBA Germany, Berlin, Germany, 6. - 7. 9. 2001 (invited lecture)

HOLOUBEK, I. Persistent, bioaccumulative and toxic chemicals � environmental levels and effects. Seminar of Max Planck Institute for Meteorology, Hamburg, Germany, 24. 9. 2001 (invited lecture)

HOLOUBEK, I. Background monitoring of POPs in ambient air in Czechia and comparison with model results. Workshop Slowly degradable organics in the atmospheric environment and air-sea exchange. Max Planck Institute for Meteorology, Hamburg, Germany, 26. 9. 2001 (invited lecture)

HOLOUBEK, I. et al. The level of soil contamination by persistent, toxic chemicals in the region of the Central and Eastern Europe. International Workshop on Assessment of the Quality of Contaminated Soils and Sites in Central and Eastern European Countries (CEEC) and New Independent States (NIS). Sofia, Bulgaria, 3.9. - 3.10. 2001.

HOLOUBEK, I. et al. The emission inventory of PAHs, PCBs, PCDDs/Fs and HCB in the Czech Republic. Joint EMEP Workshop on Emissions and emission factor estimates and TFEIP combustion and industry expert panel, , Moscow, Russia. 21. - 23. 11. 2001.


Based on the previous activities of EERO (European Environmental Research Organization), ESF (European Scientific Foundation) Network on Persistent, Bioaccumulative and Toxic chemicals (ESF Network on PBTs Chemicals) was established with the following scientific and research topics: - the fate of PBTs in the European region - source inventories, emission/deposition processes, long-range transport, transformation

processes and bioavailability of PBTs in terrestrial ecosystems, modeling of chemical fate in the environment at the local, regional and global scale with special attention to new types of chemicals and those for which inadequate monitoring data exist;

- the developing of new sampling and analytical methods for PBTs;

- the study of effects on various types and levels of biota with special attention to study of effects of environmental mixtures and study of �unknown� effects � study of phytotoxic effects, effects on soil microbial populations and soil fauna, effects on aquatic biota, the developing of mechanism-based biomarkers of effect, study of non-genotoxic carcinogenesis;

- ecological risk assessment � reliable monitoring data are needed for risk assessment and model calibrations. Research centre RECETOX is the co-ordination centre of this network. ESF Network on PBTs compounds includes 15 European and US universities and research institutes.

Research activities of RECETOX cover the Czech participation on EMEP Programme of UN ECE Convention CLRTAP and completely performed the regional background monitoring of persistent, toxic substances in the area of Ko�etice observatory of Czech Hydrometeorological Institute.

At present, RECETOX as a part of R-T&A is the implementation agency of Stockholm Convention in the Czech Republic (GEF/UNIDO project Enabling activities to facilitate early action in the implementation of the Stockholm Convention on Persistent Organic Pollutants (POPs Convention) in Czech Republic). Also RECETOX participates on the UNEP/GEF Project Regionally Based Assessment of Persistent Toxic Substances (co-ordination of region III - Europe).


Michal Boháč - University of Western Australia, Australia

Andrea Jesenská - Institute of Genetic Ecology, Japan

Zbyněk Prokop - University of Groningen, Netherlands

Petra �tejnarová - University of Bordeaux, France


Holoubek, I.: member of UNEP/IFCS � POPs Protocol � regional experts group � Regional Co-ordinator of GEF Regional Based Assessment on Persistent Toxic Substances; member of UN/ECE � Task Force for Measurements and Modelling, Task Force on Emission Inventories; member of SETAC - Society of Environmental Chemistry and Toxicology; member of SECOTOX - Society of Ecotoxicology and Chemical Safety - member of Central and Eastern European Regional Committee; member of Society for Risk Analysis; chairman of the Czech Society for Environmental Chemistry and Ecotoxicology, member of Scientific Council of Masaryk Oncological Institute; person responsible for Environmental Risk Assessment (Ministry of the Environment); member of Working group Biology and Ecology, Commission for Accreditation, Ministry of Education, Youth and Sport; member of sub-commission for Chemistry, Grant Agency, CR; chairman of the council of Ph.D. study Environmental Chemistry MU Brno, member of the council of Ph.D. study Environmental Chemistry VUT Brno, member of the council of Ph.D. study Ecology MU Brno, member of the council of Ph.D. study Food chemistry and analysis V�CHT Praha, Ecology and Applied Ecology Charles University, Praha; member of editorial board Air Protection (CR), member of editorial board Environmental Science and Pollution Research, and Acta Hydrobiologica et Hydrochimica.

Hrdlička, A.: PHARE Project Manager, Project No. EC/AIR/21-CZ. Grant evaluation for the Fund of Advancement of Universities, Ministry of Education CR. Member of the Council for Postgraduate Students (Environmental Chemistry), Faculty of Science, Masaryk University, Brno.

Du�ek, L.: Chief manager of the Center of Biostatistics and Analyses, Faculty of Medicine and Faculty of Science, Masaryk University, Brno; member of the Pedagogical and Accreditations Advisory boards, Faculty of Science, Masaryk University, Brno; member of the Czech Society for Environmental Chemistry and Ecotoxicology; member of the Czech Society for Analytical Cytometry

Laboratory of Atomic Spectrochemistry


The Laboratory provides research possibilities to students of doctoral study programmes Chemistry and Physics. The Laboratory staff participates also in teaching of students of chemistry and physics of bachelor´s and master´s study programmes. Educational activities comprise the semestrial lecture and seminar on analytical chemistry for students involved in teaching career in chemistry, semestrial lectures on analytical molecular spectrometry, spectrophotometry, analytical atomic spectrometry, spectrometry with inductively coupled plasma, plasma spectrometry, lasers in analytical chemistry, and measurement and automation. The personnel of the Laboratory is involved in laboratory exercise of analytical chemistry for students of biology, laboratory exercise concerning the methods of chemical research, and spectrometric methods for special exercise in analytical chemistry. Diploma and bachelor´s theses are focused on development of atomic emission spectrometry methods of elemental analysis using atomic spectrometry instruments i.e. two ICP spectrometers, a flame-emission high-resolution spectrometer, a pulsed laser for vaporization of solid samples, and plasma-jet excitation source. Laboratory cooperates with the Department of Analytical Chemistry and with the Plasmachemical Laboratory of the Section Physics and the Department of Physical Electronics of the Section Physics.

In the year 2001, research activities were focused on fundamental aspects of laser ablation inductively coupled plasma atomic emission spectrometry (LA-ICP-AES), on the La-ICP-AES analysis of tungsten carbide ceramics, steels, glass, agricultural soils and milk powder. Energy distribution in the crossection of the laser beam was studied. Laser ablation was coupled to high-resolution flame emission spectrometry for the analysis of solid glass samples. For this purpose, a special measuring device was designed and constructed. Development of hydride generation technique was carried out using ICP-AES for the determination of trace concentrations of selenium. Non-spectral interferences and mechanism of excitation of selenium atoms in ICP were studied. Development of device for UV-photolysis of samples with organic matrix, such as biological materials, animal or human tissues, whole blood, blood serum, plants or foodstuff was continued. Research and development of the high-frequency plasma jet and the microwave plasma torch were continued in co-operation with Plasmachemical laboratory. Development and application of method for the analysis of human bones from ancient skeletal residues were carried out for the Department of Anthropology of the Faculty of Science. Solution analysis with ICP-AES was concentrated on the determination of elements in samples of agricultural soils monitoring in co-operation with the State Agricultural Institute for Supervising and Testing. Vacuum UV spectral region was investigated with the aim of spectrochemical determination of sulphur, phosphorus, and iodine. ICP-AES methods for determination of iodine and selenium in algae Chlorella were developed.

LABORATORY STAFF

Head: Vítězslav Otruba (Associate Prof., RNDr., CSc.) Scientific Workers: Vladimír Aubrecht (Associate Prof., RNDr., CSc.), Technical University Brno, Masaryk University Brno Viktor Kanický (Associate Prof., RNDr., D.Sc.) Vratislav Kapička (Prof., RNDr., D.Sc.) Research Workers: Pavel Krásenský (Ing.) Karel Novotný (Mgr.) Technical Assistants: Jan Mikolá� (Mgr.) Věra Stuchlíková (Ing.) Jan Pí�e Secretary: Iva �afaříková Ph.D. Students: Full time: Martin �těpán (Mgr.) Jiří Machát (Mgr.) Martin Semerád (Mgr.) Markéta Va�ková (Mgr.) Eva Niedobová (Mgr.) Ale� Hrdlička (Mgr.) Lubomír Proke� (Ing.) Part time: Marie Pi�těková (RNDr.)


Diploma Theses:

Milo� Halúzka � Analysis of Thin Layers using Laser Ablation with Optical Emission Spectrometry in Inductively Coupled Plasma (supervisor: V. Kanický) Marie Sobotková � Determination of Alkali Metals using the Method of Laser Ablation with Flame Emission Spectrometry (supervisor: V. Otruba) Jitka Studýnková � Determination of Selenium using Optical Emission Spectrometry with Inductively Coupled Plasma and Hydride Generation (supervisor: V. Kanický)


Kanický V., Otruba V.: ICP course, Spectroscopic Society of J. M. Marci.


Grant Agency of the Czech Republic

203/00/0415 Responsible holder: Masaryk University Brno, Laboratory of Plasma Sources for Chemical Analysis of the faculty of Sciences. Kanický, V., Otruba, V., Novotný, K., Mikolá�, J.: The study of interaction of laser radiation with pressed powdered materials for laser ablation inductively coupled plasma atomic emission spectrometry. Special materials, ceramic powders, agricultural soils, geological samples, solid wastes are studied with methods of atomic emission, electron and laser spectroscopy.

Ministry of Education, Youth and Sports of the Czech Republic CEZ: J07/98: 143100003 Otruba, V., and co.: Laboratory of Atomic Spectrochemistry. A project of research of plasma discharges as excitation sources for spectral analysis. Programme of doctoral studies in analytical chemistry.


Kanický V.: invited lecture, Helwan University, Faculty of Science, Helwan, Egypt, April, 2001

Kanický V.: invited lecture, Ain Shams University, Faculty of Science, Cairo, Egypt, April, 2001

Kanický V.: invited lecture, Tanta University, Faculty of Science, Tanta, Egypt, April, 2001

Kanický V.: invited lecture, Benha University, Faculty of Science, Benha, Egypt, April, 2001

Kanický V.: invited lecture, University of Asiut, Faculty of Science, Asiut, Egypt, April, 2001

Kanický V.: invited lecture, Alexandria University, Faculty of Science, Alexandria, Egypt April, 2001

Kanický V.: invited lectures � 2 courses for Ph.D. students, Universidad Nacional Autonoma de Mexico, Facultad de Estudios Superiores, Cuautitlan, Mexico D.F., Mexico, May 14-16, 2001.

Novotný K.: invited lecture, Adam Mickiewicz University, Department of Water and Soil Analysis, Poznan, Poland

Kanický, V.: research stay (3 weeks) at Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France.

Otruba, V.: research stay (3 weeks) at Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France.

OTHER INTERNATIONAL CONTACTS AND CO-OPERATION

Cooperation

University of Beograd, Yugoslavia, (Prof. N. Konjevic, Kapička)

Université Claude Bernard - Lyon I, Laboratoire des Sciences Analytiques, Lyon, France (J.-M. Mermet; V. Kanický, V. Otruba).

Veterinary and Agrochemical Research Centre, Section of Ecochemistry and Spectroscopy, Tervuren, Belgium (M. Hoenig, V. Otruba, V. Kanický)

Technical University Ko�ice, Faculty of Metallurgy, Department of Chemistry, Ko�ice, Slovak republic (Prof. E. Krakovská, Otruba, Kanický)

University of Vienna, Dept. of Analytical Chemistry, Division of Atomic Spectroscopy, Vienna, Austria (Prof. I. Steffan, Kanický, Otruba)

Lina Spark Applications, S.a., Cully, Switzerland (Dipl. Ing. Wilfried Vogel, Kanický, Otruba)

Departamento de Fisica, Universidad de Cordoba. (Prof. Dr. M. Carmen Quintero Ortega, Otruba, Kanický).

Institut für Analytische Chemie, Abteilung Atomspektroskopie, Fakultät für Naturwissenschaften und Mathematik, Univesrität Wien. Spolupráce v oblasti atomové spektrochemie prvků (Univ. Prof. Dr. Ilse Steffan).

Departamento de Química Analítica, Facultad de Estudios Superiores Cuautitlán, Universidad Autonoma de Mexico, (Dr. A. L. Revilla Vazquez, Kanický, Otruba).

Adam Mickiewicz University, Department of Water and Soil Analysis, Poznan, Poland (Prof. J. Siepak; V. Kanický, K. Novotný).

Eidgenossische Technische Hochschule, Department of Inorganic Chemistry, Zürich, Switzerland, (Prof. D. Guenther; V. Kanický).

Foreign visitors

Jean-Michel Mermet (Dr.), Laboratoire des Sciences Analytiques, Université Claude Bernard, Lyon I, Villeurbanne, France, one-week stay, BARRANDE programme

Antonio Molina (Ing.), Departamento de Fisica, Universidad de Cordoba, Spain, 3 months, granted by SOCRATES/ERASMUS project, PhD.


Lubomír Proke� (Ing.), Laboratoire des Sciences Analytiques, Université Claude Bernard - Lyon I, Villeurbanne, France, 3 months, granted by SOCRATES/ERASMUS project, PhD.


Aubrecht, V.: Teaching at the Faculty of Science, Masaryk University and the Faculty of Electrical Engineering, Technical University, Brno: Electrical Discharges.

Kanický, V.: Member of the Council for Postgraduate Students (Analytical Chemistry); Head (alternating) of the Analytical Chemistry Board of Examiners for Ph.D. study; Member of the Committee of the Spectroscopic Soc. of J. M. Marci, Prague; Vice-chairman of the Working Party of Analytical Chemistry of the Czech Chemical Society; Vice-dean of the Faculty of Science.

Kapička, V.: Member of the Scientific Council of the University Ostrava and South Bohemia, České Budějovice and Biophysical Institute, Academy of Sciences of Czech Republic, Brno. Member of working group of Grant Agency, Academy of Science and Grant Agency of

Czech Republic. Member of the Council for the Postgraduate Study in Plasma Physics at the Faculty of Applied Physics, the University Plzeň, the Faculty of Mathematics and Physics, Charles University, Prague, and the Faculty of Sciences, Masaryk University, Brno. Member of the Council for the postgraduate study in applied physics, the Faculty of Science, Palacký University, Olomouc.

Otruba, V.: Member of the Council for Postgraduate Students (Analytical Chemistry); Member of the Spectroscopic Society of J. M. Marci, Prague.

PUBLICATIONS

1. Abrahámová, J. - Svobodník, A. - Du�ek, L. Nejnověj�í trendy v diagnosticko-léčebném programu zhoubných nádorů varlat (Current trends in diagnosis and treatment of testes tumors). In Vybrané otázky onkologie. V. Praha : Nakladatelství Galén, 2001., p. 13-14.

2. Bartáková, Iva - Kummerová, Marie - Mandl, Martin - Pospí�il, Michal. Phytotoxicity of iron in relation to its solubility conditions and the effect of ionic strength (Phytotoxicity of iron in relation to its solubility conditions and the effect of ionic strength). Plant and Soil, Netherlands : Kluwer Academic Publishers, 235, 1, p. 45-51. ISSN 0032-079X. 2001.

3. Bláha, Luděk - Mar�álek, Blahoslav. Dissolved microcystins in raw and treated drinking water in the Czech Republic (Dissolved microcystins in raw and treated drinking water in the Czech Republic). In Cyanotoxins - Occurence, Causes, Consequences. Berlin, Germany : Springer-Verlag, 2001., p. 212-216. ISBN 3-540-64999-9.

4. Bláha, Luděk - Machala, Miroslav - Vondráček, Jan - Neča, Jiří - Upham, Brad. In vitro assessment of non-genotoxic effects of polycyclic aromatic hydrocarbons (In vitro assessment of non-genotoxic effects of polycyclic aromatic hydrocarbons). Toxicology, Clare, Ireland : Elsevier Sci Ireland Ltd, 164, 1-3, p. 154-155. ISSN 0300-483X. 2001.

5. Bláha, Luděk - Machala, Miroslav - Breineková, Klára. Multiple oxidative stress parametetrs are modulated in vitro by oxygenated polycyclic aromatic hydrocarbons identified in river sediments (Multiple oxidative stress parametetrs are modulated in vitro by oxygenated polycyclic aromatic hydrocarbons identified in river sediments). Advances in Experimental Medicine and Biology, New York, USA : Kluwer Academic / Plenum publ., 500, 1, p. 225-228. ISSN 0065-2598. 2001.

6. Bláha, Luděk - Machala, Miroslav - Vondráček, Jan - Kapplová, Petra. Tumor-promoční aktivita polycyklických aromatických uhlovodíků a reálných extraktů vzorků vzduchu (Tumor-promotional activity of PAHs and samples of air extracts). In OVZDU�Í 2001 - Program a sborník konference. Brno : MU Brno, TOCOEN s.r.o., 2001., p. 225-226. ISBN 80-210-2591-3.

7. Bouchal, Pavel - Glatz, Zdeněk - Janiczek, Oldřich - Mandl, Martin. Application of Capillary Zone Electrophoresis to Study the Properties of Rhodanese from Acidithiobacillus ferrooxidans (Application of Capillary Zone Electrophoresis to Study the Properties of Rhodanese from Acidithiobacillus ferrooxidans). Folia Microbiologica, Praha : Institute of Microbiology of AV ČR, 46, 5, p. 385-389. ISSN 0015-5632. 2001.

8. Brablec, Antonín - Slavíček, Pavel - Kapička, Vratislav - Klíma, Milo� - Eliá�, Marek - �ícha, Milo� - Slavinská, D. - Trchová, M. - Biederman, H. Deposition of polymer films in rf discharge at atmospheric pressure (Deposition of polymer films in rf discharge at atmospheric pressure). In 15th ISPC symposium proceedings, vol VI. Orleans,France : GREMI, CNRS/University of Orleans, 2001., p. 2329-2333.

9. Brablec, Antonín - Slavíček, Pavel - Kapička, Vratislav - Klíma, Milo� - �íra, Martin. Optical diagnostics of plasma channel burning at atmospheric presssure (Optical diagnostics of plasma channel burning at atmospheric presssure). In XIV Symposyum on Physics of Switching Arc. Brno, Czech Republic : FEECS TU Brno, 2001., p. 24-26. ISBN 80-214-1949-0.

10. Brlejová, Zuzana - Pinkas, Jiří - Roesky, Herbert W. Příprava nových prekurzorů titanosilikátových materiálů (Synthesis of new precursors to titanosilicate materials). In 53. zjazd chemických spoločností, Zborník príspevkov 2. Banská Bystrica : Univerzita Mateja Bela, 2001., p. 189-190. svazek 2, B-PO33. ISBN 80-89029-23-X.

11. Bro�, Pavel - Bur�ík, Jiří - Picha, Radim. Study and modelling of the gamma and gamma' phase equilibrium in Ni-Al-Cr-Co system (Study and modelling of the gamma and gamma' phase equilibrium in Ni-Al-Cr-Co system). In Seminar on Thermodynamics of Materials. Brno : Masaryk University, Brno, 2001., p. 70-74. ISBN 80-210-2702-9.

12. Buhot, N. - Mike�, Vladimír - Douliez, JP. - Blein, JP. A lipid transfer protein binds to a receptor involved in the control of plant defence responses (A lipid transfer protein binds to a receptor involved in the control of plant defence responses). FEBS Letters, Amsterdam : Elsevier Science B.V., 2001, 509, p. 27-30. ISSN 0014-5793. 2001.

13. Cukrowska, Ewa - Trnková, Libu�e - Kizek, René - Havel, Josef. Use of artificial neural networks for the evaluation of electrochemical signals of adenine and cytosine in mixtures (Use of artificial neural networks for the evaluation of electrochemical signals of adenine and cytosine in mixtures). JOURNAL OF ELECTROANALYTICAL CHEMISTRY, Lausanne : ELSEVIER SCIENCE SA, LAUSANNE, 2001, 503, p. 117-124. ISSN 0022-0728. 2001.

14. Cukrowski, Ignacy - Farková, Marta - Havel, Josef. Evaluation of Equilibria with Use of Artificial Neural Networks (ANN). II. ANN and Experimental Design as a Tool in Electrochemical Data Evaluation for Fully Dynamic (Labile) Metal Complexes. Electroanalysis, Weinheim : WILEY-VCH Verlag GmbH, 13, 4, p. 295-308. ISSN 1040-0397. 2001.

15. Církva, Vladimír - Klán, Petr - Hájek, Milan. The Microwave Photochemical Reactor for Synthesis. In 8th Interantional Conference on Microwave and High Frequency Heating. Bayreuth, Germany : University of Bayreuth, AMPERE, 2001., p. 86-86. Book of Abstracts.

16. Častulík, Jakub - Marek, Jaromír - Mazal, Ctibor. Synthesis of spiropyrrolidines and spiropyrrolizidines by 1,3-dipolar cycloadditions of azomethine ylides to substituted a-methylene-g-lactones. Tetrahedron, Oxford (UK) : Elsevier Science Ltd., 57, 39, p. 8339-8347. ISSN 0040-4020. 2001.

17. Če�ková, Pavla - �ák, Zdirad - Havli�, Jan - Johnson, Barrie - Janiczek, Oldřich - Mandl, Martin. Partial characterisation of a colored metabolite of Acidithiobacillus ferrooxidans grown on elemental sulfur (Partial characterisation of a colored metabolite of Acidithiobacillus ferrooxidans grown on elemental sulfur). In Biohydrometallurgy: Fundamentals, Technology and Sustainable Development. Amsterdam : Elsevier, 2001., p. 363-367. ISBN 0 444 50623 3.

18. Čmelík, Richard - Pazdera, Pavel. Transformace derivátů 4L4-1,2-dithiolo[1,5-b][1,2,4]dithiazolu a 3-(R-karbonylimino)-3H-1,2-dithiolu působením dusíkatých nukleofilů (Transformation of 4L4-1,2-dithiolo[1,5-b][1,2,4]dithiazole and 3-(R-carbonylimino)-3H-1,2-dithiole derivatives by action of nitrogene nucleophiles). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 224-225. 1. ISBN 80-89029-22-1.

19. Damborský, Jiří - Rorije, Emiel - Jesenská, Andrea - Nagata, Yuji - Klopman, Gilles - Peijnenburg, Willie. Structure-specificity relationships for haloalkane dehalogenases (Structure-specificity relationships for haloalkane dehalogenases) Environmental

Toxicology and Chemistry, 20, 12, p. 2681-2689. 2001. - URL

20. Damborský, Jiří - Prokop, Martin - Koča, Jaroslav. TRITON: graphic software for rational engineering of enzymes (TRITON: graphic software for rational engineering of enzymes). Trends in Biochemical Sciences, 28, 1, p. 71-73. 2001. - URL

21. Dostál, Jiří - �ák, Zdirad - Nečas, Marek - Slavík, Jiří - Potáček, Milan. Protopine hydrochloride (Protopine hydrochloride). Acta Crystallographica Section C, Copenhagen : Munksgaard, 57, 5, p. 651-652. ISSN 0108-2701. 2001.

22. Drbálková, Eva - Janderka, Pavel. Detection of Intermediates and Products of Electrochemical Processes - A DEMS Study (Detection of Intermediates and Products of Electrochemical Processes - A DEMS Study). In Proceedings of IUPAC Internation Congress on Analytical Science 2001 (ICAS 2001). Tokyo : The Japan Society for Analytical Chemistry, 2001., p. 254-254.

23. Drbálková, Eva - Janderka, Pavel. Detection of Intermediates and Products of Electrochemical Processes-a DEMS Study (Detection of Intermediates and Products of Electrochemical Processes-a DEMS Study). Analytical Sciences, Tokyo : The Japan Soc. for Analytical Chemistry, 2001, 17, p. 993-995. ISSN 0910-6340. 2001.

24. Drbálková, Eva - Janderka, Pavel. Electrooxidation of small organic molecules on polycrystalline platinum electrode in aqueous acid solution using on-line MS study (Electrooxidation of small organic molecules on polycrystalline platinum electrode in aqueous acid solution using on-line MS study). In Proceedings of the 19th Informal Meeting on Mass Spectrometry. Nosyvaj : MS Group of the Chemical Research Center of the Hungarian Academy of Sciences,Hungary and MS Service of CNR, Italy, 2001., p. 98-99.

25. Durnová, Eva - Kotoučková, Ludmila. PŘÍNOS METODY IDENTIFIKACE MIKROORGANISMŮ POMOCÍ PROFILU MASTNÝCH KYSELIN PRO CHARAKTERIZACI GRAMPOZITIVNÍCH NEPRAVIDELNÝCH NESPORULUJÍCÍCH TYČEK. (The contribution of the method of identification of microorganisms by the use of fatty acids profile to characterisation of Gram positive irregular unsporulating rods). In Sborník 22. Kongresu Československé společnosti mikrobiologické - Zdravie a mikroorganizmy. Ko�ice - Praha : Československá společnost mikrobiologická, 2001., p. 40-40.

26. Du�ek, Ladislav - �aloudík, Jan - Svobodník, Adam. Hodnocení výsledků onkologické péče z reálných klinických dat - limity a úskalí (Evaluation of the oncology treatment results based on real clinical data - specifities and limitations). In Sborník konference XXV. Brněnské Onkologické Dny. Brno : ČOS, 2001., p. 39-43. ISBN 80-238-6935-3.

27. Du�ek, L. - �aloudík, J. - Talač, R. - Vagunda, Václav - Hofmanová, Jiřina - Kozubík, A. Mo�nosti analýz dat - od naměřeného nádorového markeru ke klinicky vyu�itelnému prediktoru (Possibilities of data analyses - from the measured tumor marker to clinical predictor). In Sborník konference Analytická cytometrie I. Brno : BFU AV ČR, 2001., p. 20-21. ISBN 80-238-6833-0.

28. Du�ek, L. - Pavli�, Petr - Svobodník, Adam - Koptíková, Jana - Regner, Břetislav - Augustin, J. - Geryk, E. - �aloudík, J. Softwarový standard analýz dat Národního onkologického registru - model karcinomu prsu (Software standard of data analyses from National Oncology registr - breast carcinoma model). In Vybrané otázky onkologie. V. Praha : Nakladatelství Galén, 2001., p. 78-81.

29. Du�ek, L. - Svobodník, A. - Pavli�, P. - Regner, B. - Koptíková, J. - Augustin, J. - Geryk, E. - �aloudík, J. Systém vizualizace dat Národního onkologického registru (software SVOD) (System of visualisation of National oncology registr data (software SVOD)). Zdravotnické noviny - Lékařské listy, 2001, 12, p. 39-41. 2001.

30. Fait, V. - Chrenko, V. - Pačovský, Z. - Du�ek, L. - �aloudík, J. Výsledky léčby pacientek s karcinomem prsu operovaných v MOU v Brně v letech 1980-1984 (The results of breast carcinoma treatment in MOU Brno 1980-1984). Praktická gynekologie, 3, 1, p. 1-6. 2001.

31. Fajkusová, Dagmar - Pazdera, Pavel. REAKCE 2,2-DIAMINODIFENYLDISULFIDU S ACYLISOTHIOKYANÁTY (REACTIONS OF 2,2-DIAMINODIPHENYLDISULFIDE WITH ACYLISOTHIOCYANATES). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 226-226. 1. ISBN 80-89029-22-1.

32. Fojt, Bohuslav. Mikroelemnty - indikátory metamorfního přepracování hornin (Microelemnts - metamorphic transformastion indicators). In Zeman, Josef. Geochémia 2001. Bratislava, Slovenská republika : PrirF UK, �GÚD�, 2001., p. 18-19. ISBN 80-88-974-33-X.

33. Foret, Rudolf - Krumpos, Josef - Sopou�ek, Jiří - Svoboda, Milan - Vře�ťál, Jan. Phase analysis of Creep-Resistant Fe-C-Cr-Mo-V(W) Steels after Long-Term Service Exposure (Phase analysis of Creep-Resistant Fe-C-Cr-Mo-V(W) Steels after Long-Term Service Exposure). Zeitschrift fur Metallkunde, Munchen : Carl Hanser Verlag, 92, 3, p. 307-310. ISSN 0044-3093. 2001.

34. Gajdo�ová, Dagmar - Pokorná, Lenka - Pro�ek, Pavel - Láska, Kamil - Havel, Josef. Are there humic acids in Antarctica? (Are there humic acids in Antarctica?). Cambridge : RSC, 2001. 11 pp. Humic substances. ISBN 0-85404-811-1.

35. Garcia-Valls, Ricard - Hrdlička, Ale� - Perůtka, Jiří - Havel, Josef - Deorkar, Nandu V. - Tavlarides, Lawrence L. - Valiente, Manuel - Muňoz, Maria. Separation of Rare Earth Elements by High-Performance Liquid Chromatography Using Covalently Modified Silica Gel Column (Separation of Rare Earth Elements by High-Performance Liquid Chromatography Using Covalently Modified Silica Gel Column). Analytica Chimica Acta, Amsterdam : Elsevier Science Publishers, 439, 2, p. 247-253. ISSN 0003-2670. 2001.

36. Glatz, Zdeněk - Nováková, Soňa - �těrbová, Hana. Analysis of Thiocyanate in Biological Fluids by Capillary Zone Electrophoresis (Analysis of Thiocyanate in Biological Fluids by Capillary Zone Electrophoresis). Journal of Chromatography A, Netherlands : Elsevier, 916, (1+2), p. 273-277. ISSN 0021-9606. 2001.

37. Gramlich, Volker - Lubal, Přemysl - Musso, Stefano - Anderegg, Giorgio. The Stability of Metal N,N,N',N'-Tetrakis(2-aminoethyl)ethane-1,2-diamine (=penten) Complexes and the X-Ray Crystal Structure of [Tl(NO3)(penten)](NO3)2 (The Stability of Metal N,N,N',N'-Tetrakis(2-aminoethyl)ethane-1,2-diamine (=penten) Complexes and the X-Ray Crystal Structure of [Tl(NO3)(penten)](NO3)2). Helvetica chimica acta, Basileae : Aedibus Georg, 84, 3, p. 623-631. 2001.

38. Halámek, Jan - Hepel, Maria - Skládal, Petr. Investigation of highly sensitive piezoelectric immunosensors for 2,4-dichlorophenoxyacetic acid (Investigation of highly sensitive piezoelectric immunosensors for 2,4-dichlorophenoxyacetic acid). Biosensors & Bioelectronics, Oxford : Elsevier Advanced Technology, 16, 3, p. 253-260. ISSN 0956-5663. 2001.

39. Havel, Josef - Fetsch, David - Peňa Méndez, Eladia María - Lubal, Přemysl - Havli�, Jan. Recent developments in humic acid charakterisation by CE and MALDI-TOF mass spectrometry (Recent developments in humic acid charakterisation by CE and MALDI-

TOF mass spectrometry). In Understanding and Managing Organic Matter in Soils, Sediments and Waters. Atlanta : IHSS, 2001., p. 77-82.

40. Havli�, Jan - Madden, John Edward - Revilla Vázquez, Alma Luísa - Havel, Josef. High Performance Liquid Chromatographic determination of deoxycytidine monophosphate and methyl-deoxycytidine monophosphate for DNA demethylation monitoring: Experimental Design and Artificial Neural Networks optimisation (High Performance Liquid Chromatographic determination of deoxycytidine monophosphate and methyl-deoxycytidine monophosphate for DNA demethylation monitoring: Experimental Design and Artificial Neural Networks optimisation). J. Chromatogr. B., Amsterdam : Elsevier Science, 2001, 755, p. 185-193. ISSN 0378-4347. 2001.

41. Havránková, Jitka - Vře�ťál, Jan - Wang, Ligen - �ob, Mojmír. Ab initio analysis of energetics of sigma-phase formation in Cr-based systems. Physical Review B, USA : The American Physical Society, 63, 17, p. 174104-1-174108. ISSN 0163-1829. 2001.

42. Havránková, Jitka - Bur�ík, Jiří - Kroupa, Ale� - Bro�, Pavel. Experimental study and thermodynamic assessment of the Ni-Al-Cr-Mo system at 1173 K (Experimental study and thermodynamic assessment of the Ni-Al-Cr-Mo system at 1173 K). Scripta Materialia, USA : Pergamon, 2001, 1, p. 121-126. ISSN 1359-6462. 2001.

43. Hilscherová, Klára - Ansorgová, Alena - Holoubek, Ivan. Distribution of polcyclic aromatic hydrocarbons among different compartments of river system (Distribution of polcyclic aromatic hydrocarbons among different compartments of river system). Toxicological and Environmental Chemistry, 80, 1, p. 95-111. ISSN 0277-2248. 2001.

44. Hilscherová, Klára - Kannan, K. - Kang, Y.-S. - Holoubek, Ivan - Machala, Miroslav - Masunaga, S. - Nakanishi, J. - Giesy, J.P. Characterization of dioxin-like activity of riverine sediments from the Czech Republic (Characterization of dioxin-like activity of riverine sediments from the Czech Republic). Environmental Toxicology and Chemistry, Pensacola, FL, USA : SETAC, 20, 8, p. 2768-2777. ISSN 0730-7268. 2001.

45. Hofman, Jakub - Du�ek, Ladislav - Dole�al, Ludvík. A proposal of new indices for soil microbial ecotoxicology. In Abstracts of SETAC 2001: 11th Annual Meeting of SETAC Europe; 6-10 May 2001, Madrid, Spain. Brussels, Belgium : SETAC Europe, 2001., p. 74-364.

46. Hofman, Jakub - Bezchlebová, Jitka. Novel approach to monitoring of soil biological quality (Novel approach to monitoring of soil biological quality). In Congress proceedings of SECOTOX 2001: Sixth European Conference on Ecotoxicology and Environmental Safety, Krakow - Poland, 20-24 August 2001. Krakow : Art-Tekst, 2001., p. 206-531. ISBN 83-88316-10-9.

47. Holoubek, Ivan - Kohoutek, Jiří � Machálek, P. - Dvořáková, I. - Bretschneider, B. - Mitera, J. - Bure�, V. - Fara, M. Emisní inventura POPs (PAHs, PCBs, PCDDs/Fs, HCB) v České republice (Emission inventory of POPs in the Czech Republic). Ochrana ovzdu�í, Praha, 13, 1, p. 17-19. ISSN 1211-0337. 2001.

48. Holoubek, Ivan - Klán, Petr - Ansorgová, Alena - Klánová, Jana - Del Favero, David. Fotochemie PBT látek v ledu: Nový potenciální zdroj kontaminace ledu? (Photochemistry of PBT Compounds in Ice: New Potential Source of Ice Contamination?). Ochrana ovzdu�í, Praha, 13 (33), 5-6, p. 1-4. ISSN 1211-0337. 2001.

49. Holoubek, Ivan - Kočan, Anton - Holoubková, Irena - Hilscherová, Klára - Kohoutek, Jiří - Falandysz, J. - Roots, O. Persistent, Bioaccumulative and Toxic Compounds in the Central and Eastern European Countries - State-of-the-Art Report - hot spots (Persistent, Bioaccumulative and Toxic Compounds in the Central and Eastern European Countries - State-of-the-Art Report - hot spots). Arch. Industr. Hyg. Toxicol., 52, 2, p. 239-251. 2001. - URL

50. Holoubek, Ivan - Kočan, Anton - Holoubková, Irena - Hilscherová, Klára - Kohoutek, Jiří - Falandysz, J. - Roots, O. Persistent, Bioaccumulative and Toxic Compounds in the Central and Eastern European Countries - State-of-the-Art Report - human exposure (Persistent, Bioaccumulative and Toxic Compounds in the Central and Eastern European Countries - State-of-the-Art Report - human exposure). Arch. Industr. Hyg. Toxicol., 52, 2, p. 181-205. 2001. - URL

51. Holoubek, Ivan - Klán, Petr - Ansorgová, Alena - Del Favero, David - Klánová, Jana. Photochemistry of PBT Compounds in Ice. In SETAC Europe 11th Annual Meeting. Madrid, Spain : SETAC, 2001., p. M/EH101-0.

52. Holoubek, Ivan - Du�ek, Ladislav - Machala, Miroslav - Čupr, Pavel - Bláha, Karel. Project IDRIS - Ecological Risk Assessment - regional approaches (Project IDRIS - Ecological Risk Assessment - regional approaches). In Assessment and Management of Environmental Risks: Cost-Efficient Methods and Applications. Dordrecht, Netherlands : Kluwer Academic Publishers, 2001., p. 283-293. ISBN 1-4020-0024-3.

53. Holoubek, Ivan - Ansorgová, Alena - Shatalov, V. - Dutchak, S. - Kohoutek, Jiří. Regional background monitoring of PBT compounds. The comparison of the results from measurements and monitoring (Regional background monitoring of PBT compounds. The comparison of the results from measurements and monitoring). Environmental Science and Pollution Research, Landsberg, Germany : Ecomed, 8, 3, p. 201-211. ISSN 0944-1344. 2001. - URL

54. Holoubek, Ivan - Ansorgová, Alena - Kohoutek, Jiří - Holoubková, Irena - Váňa, M. - Pacl, A. - Pekárek, J. - Smrčková, V. Regional background monitoring of persistent, bioaccumulative and toxic compounds in Central Europe - I:Overview of 12 years of TOCOEN project (Regional background monitoring of persistent, bioaccumulative and toxic compounds in Central Europe - I:Overview of 12 years of TOCOEN project). Meteorologický časopis, Praha, 4, 2, p. 3-18. 2001.

55. Holoubek, Ivan - �antroch, J. - Váňa, M. - Dutchak, Sergej - Shatalov, V. Superstanice EMEP - koncepční přístup (Superstation EMEP - conceptual approach). Ochrana ovzdu�í, Praha, 13, 1, p. 11-19. ISSN 1211-0337. 2001.

56. Holík, Miroslav - Halámek, Josef. CONFIDENCE ELLIPSES FOR THE QUANTITATIVE ANALYSIS FROM THE WHOLE NMR SPECTRUM. (CONFIDENCE ELLIPSES FOR THE QUANTITATIVE ANALYSIS FROM THE WHOLE NMR SPECTRUM.). In 16th NMR Valtice, 23.-25.4.2001. Brno : Masarykova univerzita v Brně, 2001., p. 44-44. ISBN 80-210-2566-2.

57. Holík, Miroslav - Halámek, Josef. CONFIDENCE ELLIPSES FOR THE QUANTITATIVE ANALYSIS WHEN THE DATA ARE CURVES. (CONFIDENCE ELLIPSES FOR THE QUANTITATIVE ANALYSIS WHEN THE DATA ARE CURVES.). In Kemometria 01. Hungary, University of Pécs : Hungarian Chemical Society, 2001., p. 2-2.

58. Holík Miroslav - Halámek Josef Transformation of a Free-Wilson Matrix into Fourier Coefficients (Transformation of a Free-

Wilson Matrix into Fourier Coefficients). Quant. Struct.-Act. Relat., Wiley-VCH, 20, 5-6, p. 422-428. ISSN 0931-8771. 2001.

59. Hrdlička, Ale� - Dolinová, Jindři�ka. Automated Hot Solvent Extraction and HPLC Determination of Atrazine and its Degradation Products in Soil (Automated Hot Solvent Extraction and HPLC Determination of Atrazine and its Degradation Products in Soil). J.Liquid Chromatogr. Rel. Technol., New York : Marcel Dekker, 24, 5, p. 721-734. ISSN 1082-6076. 2001.

60. Hájek, R. - Kořístek, Z. - Vinklárová, J. - Janovská, E. - Klabusay, M. - Doubek, M. - Dvořáková, D. - Bourková, Ludmila - Du�ek, L. - Adler, J. - Mayer, J. - Vorlíček, J. Aktivace autologního transplantátu hematopoietických kmenových buněk interleukinem 2 (Activation of autologous transplantation of haematopoietic stem cells by IL-2). Časopis lékařů českých, Praha : Česká lékařská společnost J.E. Purkyně, 140, 14, p. 430-435. ISSN 0008-7335. 2001.

61. Chakraborty, Debashis - Horchler, Sabine - Krätzner, Ralph - Varkey, Saji P. - Pinkas, Jiří - Roesky, Herbert W. - Usón, Isabel - Noltemeyer, Mathias - Schmidt, Hans-Georg. Synthesis and Structural Characterization of Functionalized Dimeric Aluminophosphonates and a Monomeric Gallophosphonate Anion (Synthesis and Structural Characterization of Functionalized Dimeric Aluminophosphonates and a Monomeric Gallophosphonate Anion). Inorg. Chem., Spojené státy americké : American Chemical Society, Washington DC, 40, 11, p. 2620-2624. ISSN 0020-1669. 2001.

62. Chrenko, V. - Du�ek, L. - Fait, V. - �aloudík, J. Výsledky léčby pacientek s karcinomem prsu operovaných v MOÚ v Brně v letech 1980-1984 (The results of the treatment of women patients with breast carcinoma from MOU Brno 1980-1984). In Sborník konference XXV. Brněnské Onkologické Dny. Brno : MOÚ, 2001., p. 61-65. ISBN 80-238-6935-3.

63. Chromá, Markéta - Pinkas, Jiří - Roesky, Herbert W. Příprava nových mezoporézních materiálů (Synthesis of new mesoporous materials). In 53. zjazd chemických spoločností, Zborník príspevkov 2. Banská Bystrica : Univerzita Mateja Bela, 2001., p. 152-153. svazek 2, B-PO13. ISBN 80-89029-23-X.

64. Janda, Lubomír - Damborský, Jiří - Rezniczek, Gerhard A. - Wiche, Gerhard. Plectin repeats and modules: strategic cysteines and their presumed impact on cytolinker (Plectin repeats and modules: strategic cysteines and their presumed impact on cytolinker). Bioessays, 23, 11, p. 1064-1069. 2001. - URL

65. Janderka, Pavel. Vyu�ití on-line hmotnostní spektrometrie v elektrochemii (Use of On-line Mass Spectrometry in Electrochemistry). In Sorník odborného semináře XXXI. moderní elektrochemické metody. Ústí nad Labem : SES Logis s.r.o Ústí nad Labem a Ústav fyzikální chemie J. Heyrovského AV ČR Praha, 2001., p. 4-4.

66. Janča, Michal - Nečas, Marek - �ák, Zdirad - Příhoda, Jiří. On the reaction of chlorodithiophosphoric acid pyridiniumbetaine with polyfunctional nucleophiles; Part II. Reaction with thiosemicarbazide derivatives. (On the reaction of chlorodithiophosphoric acid pyridiniumbetaine with polyfunctional nucleophiles; Part II. Reaction with thiosemicarbazide derivatives.). Polyhedron, Velká Británie, 2001, 20, p. 2823-2828. ISSN 0277-5387. 2001.

67. Jonas, Jaroslav. Kvantifikace chirality (Quantification of Chirality). Chemické Listy, Praha : Česká společnost chemická, 95, 6, p. 342-343. ISSN 0009-2770. 2001.

68. Kanický, Viktor - Otruba, Vítězslav - Novotný, Karel - Musil, Petr - Mermet, Jean-Michel. Calibration graphs for steels by IR laser ablation inductively coupled plasma atomic emission spectrometry (anglicky). Fresenius Journal of Analytical Chemistry, Berlin : Springer-Verlag, 370, 4, p. 387-392. ISSN 0937-0633. 2001.

69. Kanický, Viktor - Otruba, Vítězslav - Mermet, Jean-Michel. Calibration graphs for Ti, Ta and Nb in sintered tungsten carbide by infrared laser ablation inductively coupled plasma atomic emission spectrometry. Fresenius Journal of Analytical Chemistry, Berlin : Springer-Verlag, 371, 7, p. 934-938. ISSN 0937-0633. 2001.

70. Kanický, Viktor. ICP-OES jako analytická metoda (ICP-AES as an analytical method). Vítězslav Otruba. In Otruba, Vítězslav. Spektrometrie s indukčně vázaným plazmatem. 1. vyd. Brno (Czech republic) : Masarykova univerzita v Brně; Spektroskopická společnost Jana Marka Marci, 2001., p. 2-17. Sborník příspěvků semináře. ISBN 80-210-2713-4.

71. Ka�parovský, Tomá� - Milat, ML - Mike�, Vladimír - Humbert, Claude - Havel, Ladislav. Calcium signal pathway is included in the elicitation of plant cells with ergosterol (Calcium signal pathway is included in the elicitation of plant cells with ergosterol). In Abstract book Life Sicence 2001. 2001. vyd. Wien : OGBM, 2001., p. 47-47. Joint annual meeting.

72. Ka�parovský, Tomá� - Mike�, Vladimír - Milat, Marie Lousie. Role ergosterolu jako elicitoru obranné reakce u rostlin (Role of ergosterol as elicitor of plant defense reaction). In Sborník abstrakt 5. setkání biochemiků a molekulárních biologů. Brno : Přírodovědecká fakulta MU v Brně, 2001., p. 37-37.

73. Ka�parovský, Tomá� - Barták, Milo� - Hájek, Josef - Mike�, Vladimír. Vliv metabolitů václavky na obrannou reakci rostlin (Effect of metabolites from Armillaria to the defence reaction of plants). In Sborník abstrakt 22. kongresu CSSM. 2001. vyd. Ko�ice : CSSM, 2001., p. 198-198. Sborník abstrakt.

74. Kizek, René - Trnková, Libu�e - Paleček, Emil. Determination of Metallothionein at Femtomole Level by Constant Current Stripping Chronopotentiometry (Determination of Metallothionein at Femtomole Level by Constant Current Stripping Chronopotentiometry). Anal. Chem., USA : American Chemical Society, 2001, 20, p. 4801-4808. ISSN 0003-2700. 2001. Metallothionein, Constant current stripping chronopotentiometry, Catalytic hydrogen evolution, Cyprinus carpio.

75. Kizek, René - Prů�a, Richard - Gregor, Tomá� - Fi�era, Miroslav - Vacek, Jan - Adam, Vojtěch - Trnková, Libu�e - Koutník, Vilém. Koncentrace selenu a zinku v krevním séru dětí (Selenium and zinc concentrations in blood serum of children). In 53. zjazd chemických spoločností, Banská Bystrica, Slovensko. Banská Bystrica, Slovensko : FPV univerzita Mateja Bela, Banská Bystrica, Slovensko, 2001., p. N-P40-0. Zborník príspevkov. ISBN 80-89029-24-8.

76. Kizek, René - Brázdová, Marie - Entlicherová, Marie - Marečková, Marie - Billová, Sabina - Havran, Luděk - Vacek, Jan - Adam, Vojtěch - Trnková, Libu�e - Jelen, Franti�ek. Mo�nosti stanovení proteinů (Possibility of protein determination). In 53. zjazd chemických spoločností. Banská Bystrica, Slovensko : FPV, Univerzita Mateja Bela v Banské Bystrici, 2001., p. A-P 16-1. Zborník príspevkov. ISBN 80-89029-24-8.

77. Klán, Petr - Klánová, Jana - Holoubek, Ivan - Nosek, Jan. Ice as a Medium for Phototransformations of Organic Pollutants. In 9th Congress of ESP. Lillehammer : ESP, 2001., p. 141-141. 9th ESP 2001.

78. Klán, Petr - Literák, Jaromír - Relich, Stanislav. Molecular Photochemical Thermometers. Investigation of Microwave Superheating Effects By Temperature Dependent Photochemical Processes. Journal of Photochemistry and Photobiology A: Chemistry, Amsterdam, The Netherlands : Elsevier Science, 143, 1, p. 49-57. ISSN 1010-6030. 2001.

79. Klán, Petr - Del Favero, David - Ansorgová, Alena - Klánová, Jana - Holoubek, Ivan. Photodegradation of Halobenzenes in Water Ice. Environmental Science and Pollution Research, Landsberg, Germany : Ecomed, 8, 3, p. 195-200. ISSN 0944-1344. 2001. - URL

80. Klán, Petr - Nosek, Jan - Klánová, Jana - Holoubek, Ivan. Photodegradation of Halophenols in Water Ice. In Secotox World Congress. Krakow, Poland : Secotox, 2001., p. 155-155. Secotox 2001. ISBN 83-88316-10-9.

81. Klán, Petr - Pelliccioli, Anna P. - Wirz, Jakob - Zabadal, Miroslav. Phototriggers from Substituted ortho-Methyl Acetophenones (Phototriggers from Substituted ortho-Methyl Acetophenones). In Joint Meeting of the Italian, French, and Swiss Photochemistry Groups. Lausanne, Switzerland : Ecole Polytechnique Fédérale de Lausanne, 2001., p. 33-33.

82. Klán, Petr - Hájek, Milan - Církva, Vladimír. The Electrodeless Discharge Lamp: A Prospective Tool for Photochemistry - Part 3: The Microwave Photochemistry Reactor. Journal of Photochemistry and Photobiology A: Chemistry, Amsterdam, The Netherlands : Elsevier Science, 140, 3, p. 185-189. ISSN 1010-6030. 2001.

83. Klán, Petr - Zabadal, Miroslav - Pospí�il, Tomá� - Heger, Dominik - Pelliccioli, Anna Paola - Wirz, Jakob. 2.5-Dimethylphenacyl Chromophore: A Photochemical Switch. In Younger Chemist Meeting. Regensburg, Germany : Universitat Regensburg, 2001., p. 7-7.

84. Klíma, Milo� - �íra, Martin - Kapička, Vratislav - Janča, Jan - Slavíček, Pavel. Diagnostics of hf-plasma pencil in liquids (Diagnostics of hf-plasma pencil in liquids). In XIV Symposium on Physics of Switching Arc. Brno, Czech Republic : FEECS TU BRNO, 2001., p. 93-96. ISBN 80-214-1949-0.

85. Kmuníček, Jan - Luengo, Santos - Gago, Federico - Ortiz, Angel Ramirez - Wade, Rebecca - Damborský, Jiří. Comparative binding energy (COMBINE) analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 (Comparative binding energy (COMBINE) analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10). Biochemistry, 40, 30, p. 8905-8917. 2001. - URL

86. Knápek, Jan - Konečná, Marie - Jarkovský, Jiří - Trnková, Libu�e - Kizek, René. Stanovení metallothioneinu v tkáních okouna říčního a kapra obecného(Perca fluviatilis L., Cyprinus carpio L.) (Detection of metallothionein in fish tissues-Perca fluviatilis L., Cyprinus carpio L.). In Sborník:5.pracovní setkání biochemiků a molekulárních biologů, Brno 2001. MU v Brně. Brno : Masarykova univerzita v Brně, 2001., p. 56-56. 1. ISBN 80-210-2538-7.

87. Knápek, Jan - Konečná, Marie - Vacek, Jan - Adam, Vojtěch - Jarkovský, Jiří - Kizek, René - Trnková, Libu�e. Stanovení MT a tě�kých kovů spektrální a elektrochemickou metodou v různých tkáních (Determination of MT and heavy metals by electrochemical methods in tissues). In Moderní elektrochemické metody. Ústí nad Labem : SES Logis s ÚFCH J.H., 2001., p. 15-15. Moderní elektrochemické metody.

88. Komárek, Josef. Speciace (Speciation). In Spektrometrie s indukčně vázaným plazmatem. Brno : Masarykova univerzita v Brně ve spolupráci se Spektroskopickou společností Jana Marka Marci, 2001., p. 62-66. ISBN 80-210-2713-4.

89. Konečná, Marie - Knápek, Jan - Vacek, Jan - Adam, Vojtěch - Jarkovský, Jiří - Strouhal, Martin - Trnková, Libu�e - Kizek, René - Koutník, Vilém. Stanovení tě�kých kovů v tkáních Okouna říčního (Perca fluviatilis L.) a Kapra obecného (Cyprinus carpio L.) (Determination of heavy metals in fish tissues (Perca fluviatilis L., Cyprinus carpio L.)). In V. Pracovní setkání biochemiků a molekulárních biologů. 1. vydání. Brno : Masarykova univerzita v Brně, 2001., p. 57-57. ISBN 80-210-2538-7.

90. Kotoučková, Ludmila - Neča, Jiří - Němec, Miroslav. Bakteriální degradace nitroguajakolů a jejich směsí s dal�ími nitroaromáty (Bacterial degradation of nitroguaiacols and their mixtures with other nitroaromates). In Sborník 22. Kongresu Československé společnosti mikrobiologické - Zdravie a mikroorganizmy. Ko�ice - Praha : Československá společnost mikrobiologická, 2001., p. 53-53.

91. Kotoučková, Ludmila - Neča, Jiří - Němec, Miroslav. Biodegradace směsí nitrofenolů a příbuzných látek (Biodegradation of mixtures of nitrophenols and related compounds). In Biodegradace V. 1. vydání. Praha : Vydavatelství V�CHT Praha, 2001., p. 133-133. 010307. ISBN 80-7080-419-X.

92. Kotoučková, Ludmila - Cmunt, Kamil - Novotný, David - Němec, Miroslav. Mikroorganismy a mikrobiologie - CD-ROM (Microorganisms and microbiology - CD-ROM). In Sborník 22. Kongresu Československé společnosti mikrobiologické - Zdravie a mikroorganizmy. Ko�ice - Praha : Československá společnost mikrobiologická, 2001., p. 211-211.

93. Kotoučková, Ludmila - Němec, Miroslav - Neča, Jiří - Navrátilová, Jitka - Sedláček, Ivo. 4-Nitroguaiacol as product and substrate of bacterial metabolism (4-Nitroguaiacol as product and substrate of bacterial metabolism). In V. Pracovní setkání biochemiků a molekulárních biologů. 1. vydání. Brno : Masarykova univerzita v Brně, 2001., p. 23-23. ISBN 80-210-2538-7.

94. Kotulanová, Alice - Komárek, Josef. Determination of copper in biological materials by atomic absorption spectrometry. In 12th International symposium Spectroscopy in Theory and Practice. Book of abstracts. Ljubljana : Spectroscopic Section of the Slovenian Chemical Society, 2001., p. 58-58.

95. Koutná, Dobromila - Galiová, Michaela - Zlochová, Veronika - Vacek, Jan - Adam, Vojtěch - Gregor, Tomá� - Fi�era, Miroslav - Trnková, Libu�e - Kizek, René - Koutník, Vilém. Vliv selenu, zinku a kadmia na růstový vývoj česneku kuchyňského (Influence of Se,Zn and Cd on growth of allium). In 53.zjazd chemických spoločností, Banská Bystrica, Slovensko. Banská Bystrica, Slovensko : FPV, Univerzita Mateja Bela , Banská Bystrica, Slovensko, 2001., p. J-PO 14-0. Zborník príspevkov. ISBN 80-89029-24-8.

96. Koča, Jaroslav - Zhan, Chang-Guo - Rittenhouse, Robert - Ornstein, Rick. Mobility of the Active Site bound Paraoxon and Sarin in Zinc-Phosphotriesterase by Molecular Dynamics Simulation and Quantum (Mobility of the Active Site bound Paraoxon and Sarin in Zinc-Phosphotriesterase by Molecular Dynamics Simulation and Qunatum). Journal of the American Chemical Society, Washington, D.C. : American Chemical Society, 123, 1, p. 817-826. ISSN 0002-7863. 2001.

97. Krejčí, Lumír - Damborský, Jiří - Thomsen, B. - Duno, M. - Bendixen, C. Molecular dissection of interactions between Rad51 and members of the recombination-repair group (olecular dissection of interactions between Rad51 and members of the recombination-repair group). Molecular and Cellular Biology, 21, 3, p. 966-976. 2001.

98. Kroupa, Ale� - Havránková, Jitka - Coufalová, Martina - Svoboda, Milan - Vře�ťál, Jan. Phase Diagram in Iron-rich Corner of the Fe-Cr-Mo-V-C System below 1000 K (Phase Diagram in Iron-rich Corner of the Fe-Cr-Mo-V-C System below 1000 K). Journal of Phase Equilibria, Ohio : ASM International, 22, 3, p. 312-323. ISSN 1054-9714. 2001.

99. Kulhánek, Petr - Vícha, Robert - Čmelík, Richard - Potaček, Milan. Automatizovaný systém zkou�ení KERBEROS (Automatic system of examination KERBEROS). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 138-138. 1. ISBN 80-89029-22-1.

100. Kulhánek, Petr - Man, Stanislav - Potáček, Milan. Nesymetrický allenylazin jako prekurzor pro smí�ené intra-inter-molekulární criss-cross cykloadice (Nonsymetrical allenylazine as precursor for a mixed intra-inter molecular criss-cross cycloadditions). In Zborník príspevkov (53. Zjazd chemických spoločností). 1. vyd. Bánská Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 166-167. č. svazku 3. ISBN 80-89029-24-8.

101. Kvasničková, Leona - Glatz, Zdeněk - �těrbová, Hana - Kahle, Vladislav - Slanina, Jiří - Musil, Pavel. Application of Capillary Chromatography using Macroporous Polyacrylamide Columns for the Analysis of Lignans from Seeds of Schisandra chinensis (Application of Capillary Chromatography using Macroporous Polyacrylamide Columns for the Analysis of Lignans from Seeds of Schisandra chinensis). Journal of Chromatography A, Netherlands : Elsevier, 916, (1+2), p. 265-271. ISSN 0021-9606. 2001.

102. Kvasničková, Leona - �těrbová, Hana - Glatz, Zdeněk - Kahle, Vladislav - Slanina, Jiří. Determination of Biologically Active Compounds in Medicinal Plants by Capillary Electrochromatography (Determination of Biologically Active Compounds in Medicinal Plants by Capillary Electrochromatography). In Book of abstract 2nd International symposium "Separations in BioSciences SBS 2001". Prague : Czech Chemical Society, 2001., p. 85-85. ISBN 80-7080-437-8.

103. Kvasničková, Leona - �těrbová, Hana - Glatz, Zdeněk - Kahle, Vladislav - Slanina, Jiří - Musil, Pavel. Stanovení biologicky aktivních látek v léčivých rostlinách pomocí kapilární elektrochromatografie (Determination of Biologically Active Compounds in Medicinal Plants by Capillary Electrochromatography). In Sborník abstrakt 5. setkání biochemiků a molekulárních biologů. Brno : Přírodovědecká fakulta MU v Brně, 2001., p. 47-48. ISBN 80-210-2538-7.

104. Kří�, Zdeněk - Carlsen, Per H.J. - Koča, Jaroslav. Conformational features of linear and cyclic enkephalins. A computational study. Journal of Molecular Structure (Theochem), Netherlands : Elsevier Science, 540, 1, p. 231-250. ISSN 0166-1280. 2001.

105. Laureova, L. - Du�ek, L. - Spurný, V. - Rovný, A. - Rejthar, Ale� - Kocák, Ivo - Kovařík, J. Relation of prenephrectomy CD profiles and serum cytokines to the disease outcome and response to IFN-alpha/IL-2 therapy in renal cell carcinoma patients (Relation of prenephrectomy CD profiles and serum cytokines to the disease outcome and response to IFN-alpha/IL-2 therapy in renal cell carcinoma patients). Oncol. Rep., Athens, Greece : PROFESSOR D A SPANDIDOS, 8, 3, p. 685-692. ISSN 1021-335X. 2001.

106. Laureova, L. - Kocák, Ivo - Du�ek, L. - �imíčková, M. - Vagundová, Marcela - Kovařík, J. The relationship of CD4 Th1/Th2 activity with the response of malignant melanoma patients to immunotherapy (The relationship of CD4 Th1/Th2 activity with the response of malignant melanoma patients to immunotherapy). Int J Mol Med, Athens, Greece : PROFESSOR D A SPANDIDOS, 1, 1, p. 258-258. ISSN 1107-3756. 2001.

107. Lubal, Přemysl - Godula, Tomá� - Havel, Josef. The Complexation of Palladium(II) with Chloroacetate. Chemical Papers, Bratislava : SAV, 55, 3, p. 157-161. ISSN 0366-6352. 2001.

108. Lubal, Přemysl - Kývala, Mojmír - Hermann, Petr - Holubová, Jana - Rohovec, Jan - Havel, Josef - Luke�, Ivan. Thermodynamic and kinetic study of Copper(II) Complexes with N-methylene(phenylphosphinic) Derivatives of Cyclen and Cyclam (Thermodynamic and kinetic study of Copper(II) Complexes with N-methylene(phenylphosphinic) Derivatives of Cyclen and Cyclam). Polyhedron, Velká Británie : Elsevier Science Ltd., 20, 1, p. 47-55. ISSN 0277-5387. 2001.

109. Luká�ková, Marcela - Brus, Jiří - Trávníček, Zdeněk - Popa, Igor - Dole�al, Karel - Marek, Radek. NMR spektroskopie derivátů 6-benzylaminopurinu. Část II. Komplexace a heteronukleární NMR (NMR Spectroscopy of 6-Benzylaminopurine Analogues. Part II. Complexation and Heteronuclear NMR). Chemické listy, Praha : ČSCH, 95, 11, p. 759-759. ISSN 0009-2770. 2001.

110. Machala, Miroslav - Vondráček, Jan - Bláha, Luděk - Ciganek, Miroslav - Neča, Jiří. Aryl hydrocarbon receptor mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay (Aryl hydrocarbon receptor mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay). MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, Amsterdam, Netherlands : ELSEVIER SCIENCE BV, 497, 1, p. 49-62. ISSN 1383-5718. 2001.

111. Machala, Miroslav - Bláha, Luděk - Vondráček, Jan. Biochemický monitoring in vitro organických kontaminantů přítomných v ovzdu�í (Biochemical monitoring in vitro of organic air pollutants). In OVZDU�Í 2001 - Program a sborník konference. Brno : MU Brno, TOCOEN s.r.o., 2001., p. 176-181. ISBN 80-210-2591-3.

112. Machala, Miroslav - Du�ek, Ladislav - Hilscherová, Klára - Kubínová, Renata - Jurajda, Petr - Neča, Jiří - Ulrich, Robert - Gelnar, Milan - Studničková, Z. - Holoubek, Ivan. Determination and multivariate statistical analysis of biochemical responses to environmental contaminants in feral freshwater fish Leuciscus cephalus (Determination and multivariate statistical analysis of biochemical responses to environmental contaminants in feral freshwater fish Leuciscus cephalus). Environmental Toxicology and Chemistry, Pensacola, FL, USA : SETAC, 20, 5, p. 1141-1148. ISSN 0730-7268. 2001.

113. Machala;, Miroslav - Neča, Jiří - Bláha, Luděk - Dejmek, Jan - �rám, R.J. Aromatase (CYP19) and 7-ethoxyresorufin O-deethylase (CYP1A1) activities in human placental samples collected in two Czech Areas Differing in Pollution Rates (Aromatase (CYP19) and 7-ethoxyresorufin O-deethylase (CYP1A1) activities in human placental samples collected in two Czech Areas Differing in Pollution Rates). In TEPLICE PROGRAM. Praha : Academia, 2001., p. 139-144.

114. Macháčková, Eva - Damborský, Jiří - Valík, Dalibor - Foretová, Lenka. Four novel germline BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer (Four novel germline BRCA1 and BRCA2 mutations in breast and breast-ovarian cancer). Human Mutation, 18, 1, p. 545-549. 2001. - URL

115. Maleček, Jiří - Hada�ová, Eva - Havel, Josef. Capillary zone electrophoresis determination of perphenazine in pharmaceutical preparations and in human serum. J. Capillary Electrophoresis, Shelton : ISC Technical Publications, Inc., 6, 5/6, p. 151-155. ISSN 1079-5383. 2001.

116. Man, Stanislav - Dostál, Jiří - Nečas, Marek - �ák, Zdirad - Potáček, Milan. Berberine and Coptisine in Liquid Ammonia (Berberine and Coptisine in Liquid Ammonia). Heterocyclic Communications, London : Freund Publishing House, 7, 3, p. 243-248. ISSN 0793-0283. 2001.

117. Man, Stanislav - Potáček, Milan - Nečas, Marek - �ák, Zdirad - Dostál, Jiří. Molecular and Crystal Structures of Three Berberine Derivatives (Molecular and Crystal Structures of Three Berberine Derivatives). Molecules, Basel : MDPI, 6, 5, p. 433-441. ISSN 1420-3049. 2001.

118. Mandl, Martin - Če�ková, Pavla - Helánová, �árka. Acidophilic bacteria in oxidation of elemental sulfur (Acidophilic bacteria in oxidation of elemental sulfur). In New trends in mineral processing IV. Ostrava : Institute of Environmental Engineering, Technical University Ostrava, 2001., p. 43-49. ISBN 80-7078-885-2.

119. Marek, Radek - Brus, Jiří - Tou�ek, Jaromír. Gradient Inverse 15N NMR Spectroscopy of Nitrogen Heterocycles. In CZ-PL-D-Younger Chemist Meeting 2001. 1. vyd. Regensburg : Universitet Regensburg, 2001., p. 26-26.

120. Marek, Radek - Luká�ková, Marcela - Brus, Jiří - Trávníček, Zdeněk - Kolehmainen, Erkki. NMR Spectroscopy of 6-Benzylaminopurine Analogues. Part I. 15N NMR and Protonation Study. Chemické listy, Praha : ČSCH, 95, 11, p. 760-761. ISSN 0009-2770. 2001.

121. Marek, Radek - Brus, Jiří - Tou�ek, Jaromír. N7- and N9-Substituted Purine Analogues - 15N NMR Study. In 16th NMR Valtice - Meeting of Central European NMR Discussion Groups. 1. vyd. Brno : Masaryk University, 2001., p. 13-13. ISBN 80-210-2566-2.

122. Marek, Radek - Lyčka, Antonín. 15N NMR spektroskopie ve strukturní analýze (15N NMR Spectroscopy in Structural Analysis). In XXV. konference organických chemiků. Pardubice : Univerzita Pardubice, 2001., p. PL04-1-4. ISBN 80-7194-349-5.

123. Marvanová, Soňa - Nagata, Yuji - Wimmerová, Michaela - Sýkorová, Jana - Hynková, Kamila - Damborský, Jiří. Biochemical characterization of broad-specificity enzymes using multivariate experimental design and a colorimetric microplate assay: characterization of the haloalkane dehalogenase mutants (Biochemical characterization of broad-specificity enzymes using multivariate experimental design and a colorimetric microplate assay: characterization of the haloalkane dehalogenase mutants). Journal of Microbiological Methods, 44, 1, p. 149-157. 2001. - URL

124. Mar�álek, Blahoslav - Bláha, Luděk. Biologicky aktivní látky produkované v biofilmech vodárenských systémů (Biologically active metabolites produced by biofilms in drinking water treatment plants). In Aktuální otázky vodárenské biologie, sborník 17. semináře. Praha : Nakladatelství V�CHT, 2001., p. 40-45. ISBN 80-7080-413-0.

125. Mar�álek, Blahoslav. Cyanobakterie jako producenti biologicky aktivních látek a jejich vliv na zdraví obyvatel (Cyanobacteria producing bioactive metabolites and their effects on human health). SOVAK, Praha, 10, 5, p. 12-15. 2001.

126. Mar�álek, Blahoslav. Ekotoxikologické biotesty v systému identifikace rizik pro �ivotní prostředí (Ecotoxicological biotests - role in the environmental risk assessment). In Sborník konference Ekoanalytika. Praha : Ekoanalytika, 2001., p. 100-105.

127. Mar�álek, Blahoslav - Bláha, Luděk - Turánek, Jaroslav - Neča, Jiří. Microcystin-LR and total microcystin in cyanobacterial blooms in the Czech Republic 1993-1998 (Microcystin-LR and total microcystin in cyanobacterial blooms in the Czech Republic 1993-1998). In Cyanotoxins - Occurence, Causes, Consequences. Berlin, Germany : Springer-Verlag, 2001., p. 56-62. ISBN 3-540-64999-9.

128. Mar�álek, Blahoslav. Toxiny sinic a současná realita v ČR (Cyanobacterial toxins - current status in the Czech Rep.). SOVAK, Praha, 10, 3, p. 56-59. 2001.

129. Mazoch, Jiří - Kučera, Igor. FNR rodina regulačních proteinů. Přehled mechanismu aktivace proteinů FNR-typu a jejich funkce při genové expresi anaerobních genů (FNR family of regulatory proteins. Survey of activation mechanism of FNR-like proteins and their function in expression of anaerobic genes). In 22. Kongres Československej spoločnosti mikrobiologickej s medzinárodnou účasťou. ZDRAVIE A MIKROORGANIZMY. Ko�ice, SR : Univerzita veterinárskeho lekárstva, Ko�ice, 2001., p. 65-65. Abstrakty.

130. Mike�, Vladimír - Ka�parovský, Tomá� - Milat, Marie Louise - Blein, Jean Pierre. Elicitory obranných reakcí rostlin (Elicitors of palnt defense reactions). In Sborník abstrakt 5. setkání biochemieků a mol. biologů. Brno : Přírodovědecká fakulta MU, 2001., p. 14-14.

131. Mohamed, Walid Fathalla - Pazdera, Pavel. One-pot Synthesis of N1-(2-Phenyl-4-quinazolinyl)-2--R-1-hydrazinecarbothioamide (One-pot Synthesis of N1-(2-Phenyl-4-quinazolinyl)-2--R-1-hydrazinecarbothioamide). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 277-278. 1. ISBN 80-89029-22-1.

132. Mohamed, Walid Fathalla - Čajan, Michal - Pazdera, Pavel - Marek, Jaromír. One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate (One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate). Molecules, Basel : MDPI, 6, 2, p. 584-597. ISSN 1420-3049. 2001.

133. Mohamed, Walid Fathalla - Čajan, Michal - Pazdera, Pavel - Marek, Jaromír. One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano-phenyl)benzimidoyl isothiocyanate (One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano-phenyl)benzimidoyl isothiocyanate). Molecules, Basel : MDPI, 6, 2, p. 588-602. ISSN 1420-3049. 2001.

134. Mohamed, Walid Fathalla - Čajan, Michal - Pazdera, Pavel. Regioselectivity of Electrophilic Attack on 4-Methyl-1-thioxo-1,2,4,5-tetrahydro[1,2,4]triazolo[4,3-a]quinazolin-5-one. (Regioselectivity of Electrophilic Attack on 4-Methyl-1-thioxo-1,2,4,5-tetrahydro[1,2,4]triazolo[4,3-a]quinazolin-5-one.). Molecules, Basel : MDPI, 6, 5, p. 557-573. ISSN 1420-3049. 2001.

135. Mohamed, Walid Fathalla - Čajan, Michal - Marek, Jaromír - Pazdera, Pavel. The Intramolecular Cycloadditon Reaction of N'-Alkyl-N3-[[(2-cyanophenyl)imino](phenyl)methyl]thioureas (The Intramolecular Cycloadditon Reaction of N'-Alkyl-N3-[[(2-cyanophenyl)imino](phenyl)methyl]thioureas). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 231-232. 1. ISBN 80-89029-22-1.

136. Mohamed, Walid Fathalla - Pazdera, Pavel. The reactivity of N3-Aryl-N1-(2-phenylquinazolin-4-yl)thioureas (The reactivity of N3-Aryl-N1-(2-phenylquinazolin-4-yl)thioureas). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 279-280. 1. ISBN 80-89029-22-1.

137. Mohamed Walid Fathalla - Pazdera Pavel The Reactivity Study on N3 N3-(3-Oxapentan-1 5-diyl)-N1-(2-phenyl-3 4-

dihydroquinazolin-4-ylidene)thioureas (The Reactivity Study on N3, N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-ylidene)thioureas). In XXVth Conference of Organic Chemists. 1. vyd. Pardubice : Publishing House of Pardubice University, 2001., p. KS 8-1. ISBN 80-7194-349-5.

138. Mohamed, Walid Fathalla - Čajan, Michal - Marek, Jaromír - Pazdera, Pavel. The Reactivity Study on N3,N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea (The Reactivity Study on N3,N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea). In Proceedings of ECSOC-5, The Fifth International Electronic Conference on Synthetic Organic Chemistry, http://www.mdpi.org/ecsoc-5.htm. 1. vyd. Basel : MDPI, Basel, Switzerland, 2001., p. [a0049]-0. ISBN 3-906980-06-5. - URL

139. Mohamed, Walid Fathalla - Marek, Jaromír - Pazdera, Pavel. The Reactivity Study on N3,N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea. Part 2: Reaction with Phenacyl Bromides and Chloroacetic Acid Derivatives (The Reactivity Study on N3,N3-(3-Oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea. Part 2: Reaction with Phenacyl Bromides and Chloroacetic Acid Derivatives). In Proceedings of ECSOC-5, The Fifth International Electronic Conference on Synthetic Organic Chemistry, http://www.mdpi.org/ecsoc-5.htm. 1. vyd. Basel : MDPI, Basel, Switzerland, 2001., p. [a0048]-0. ISBN 3-906980-06-5. - URL

140. Mohamed, Walid Fathalla - Pazdera, Pavel. The regioselectivity of the thioamide moiety against electrophiles and nucleophiles (The regioselectivity of the thioamide moiety against electrophiles and nucleophiles). In Sborník príspevkov 53. zjazd Chemických spoločností. 1. vyd. Banká Bystrica : FPV Univerzita Mateja Bela v Banskej Bystrici, 2001., p. 229-230. 1. ISBN 80-89029-22-1.

141. Mohamed, Walid Fathalla - Pazdera, Pavel. The Synthesis of New N3-Aryl-N1-(2-phenylquinazolin-4-yl)thioureas (The Synthesis of New N3-Aryl-N1-(2-phenylquinazolin-4-yl)thioureas). In XXVth Conference of Organic Chemists. 1. vyd. Pardubice : Publishing House of Pardubice University, 2001., p. KS 8-1. ISBN 80-7194-349-5.

142. Nagata, Yuji - Mori, Katsuki - Takagi, Masamichi - Murzin, Alexey G. - Damborsky, Jiri. Identification of protein fold and catalytic residues of g-hexachlorocyclohexane dehydrochlorinase LinA (Identification of protein fold and catalytic residues of g-hexachlorocyclohexane dehydrochlorinase LinA). PROTEINS: Structure, Function, and Genetics, 45, 4, p. 471-477. 2001. - URL

143. Navrátilová, Iva - Skládal, Petr - Viklický, Vladimír. Development of piezoelectric immunosensors for measurement of albuminuria (Development of piezoelectric immunosensors for measurement of albuminuria). Talanta, Elsevier Science, 55, 11, p. 831-839. ISSN 0039-9140. 2001.

144. Navrátilová, Jitka - Kotoučková, Ludmila - Němec, Miroslav - Sedláček, Ivo - Durnová, Eva. Degradation of 4-nitrocatechol and other nitroaromatic compounds by Rhodococcus opacus J3 (Degradation of 4-nitrocatechol and other nitroaromatic compounds by Rhodococcus opacus J3). In V. Pracovní setkání biochemiků a molekulárních biologů. 1. vydání. Brno : Masarykova univerzita v Brně, 2001., p. 23-23. ISBN 80-210-2538-7.

145. Navrátilová, Hana. Enantiomeric analysis of (3S,4R)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine by 19F NMR spectroscopy (Enantiomeric analysis of (3S,4R)-4-(4-fluorophenyl)-3-hydroxymethyl-1-methylpiperidine by 19F NMR spectroscopy). Magnetic Resonance in Chemistry, Great Britain : Willey and Sons, Ltd., 39, 11, p. 727-730. ISSN 0749-1581. 2001.

146. Navrátilová, Hana. Use of S-Mosher acid as a chiral solvating agent for enantiomeric analysis of some trans-4-(4-fluorophenyl)-3-substituted-1-methylpiperidines by means of NMR spectroscopy (Use of S-Mosher acid as a chiral solvating agent for enantiomeric analysis of some trans-4-(4-fluorophenyl)-3-substituted-1-methylpiperidines by means of NMR spectroscopy). Chirality, USA : Willey-Liss, 13, 10, p. 731-735. ISSN 0899-0042. 2001.

147. Necas, Marek - Foreman, Mark R. St J. - Marek, Jaromír - Woollins, John Derek - Novosad, Josef. New mixed-donor unsymmetrical P-N-P ligands and their palladium(II) complexes (New mixed-donor unsymmetrical P-N-P ligands and their palladium(II) complexes). New Journal of Chemistry, Cambridge : Royal Soc Chemistry, 25, 10, p. 1256-1263. ISSN 1144-0546. 2001.

148. Nečas, Marek - Novosad, Josef. Ammonolysis of Ph2PCl - a simple route to Ph2P-NH-PPh2 (Ammonolysis of Ph2PCl - a simple route to Ph2P-NH-PPh2). Phosphorus Research Bulletin, Japan, 12, 2001, p. 73-76. 2001.

149. Nečas, Marek - Dostál, Jiří - Slavík, Jiří. (-)-Argemonine hemihydrate ((-)-Argemonine hemihydrate). Acta Crystallographica Section C, Copenhagen : Munksgaard, 57, 1, p. 66-67. ISSN 0108-2701. 2001.

150. Nečas, Marek - Novosad, Josef - Husebye, Steinar. Tellurium complexes with new, large-bite dithio ligands. The crystal structures of cis- and trans- [Te{Ph2P(S)-N-P(S)(OPh)(2)}(2)] and [(4-MeOC6H4TeCl3)(2){mu-(Pr2P)-Pr-i(S)-Fc-P(S)Pr-i(2)}] (Tellurium complexes with new, large-bite dithio ligands. The crystal structures of cis- and trans- [Te{Ph2P(S)-N-P(S)(OPh)(2)}(2)] and [(4-MeOC6H4TeCl3)(2){mu-(Pr2P)-Pr-i(S)-Fc-P(S)Pr-i(2)}]). Journal of Organometallic Chemistry, Lausanne : Elsevier Science, 2001, 1-2, p. 124-130. ISSN 0022-328X. 2001.

151. Nečas, Marek - Novosad, Josef - Ly, Tuan Q. - �ák, Zdirad - Woollins, John Derek. The first six membered genuine heterocycle: [Ph3PCu{Ph2P(S)-N-C(O)Ph}] (The first six membered genuine heterocycle: [Ph3PCu{Ph2P(S)-N-C(O)Ph}]). Phosphorus, Sulfur Silicon Rel. Elem., Philadelphia, USA : Gordon Breach Publishing, 2001, 168, p. 379-382. ISSN 1042-6507. 2001.

152. Nečas, Marek - Beran, Martin - Woollins, John Derek - Novosad, Josef. The synthesis and characterisation of bis(diisopropylphosphoryl)ferrocene Fe[(C5H4)P(O)i-Pr2]2, bis(diisopropylthiophosphoryl)ferrocene Fe[(C5H4)P(S)i-Pr2]2 and bis(diisopropylselenophosphoryl)ferrocene Fe[(C5H4)P(Se)i-Pr2]2 (The synthesis and characterisation of bis(diisopropylphosphoryl)ferrocene Fe[(C5H4)P(O)i-Pr2]2, bis(diisopropylthiophosphoryl)ferrocene Fe[(C5H4)P(S)i-Pr2]2 and bis(diisopropylselenophosphoryl)ferrocene Fe[(C5H4)P(Se)i-Pr2]2). Polyhedron, Oxford, UK : PERGAMON-ELSEVIER SCIENCE LTD, 20, 7-8, p. 741-746. ISSN 0277-5387. 2001.

153. Nečas, Marek - Foreman, Mark, R. St J. - Dastych, Dalibor - Novosad, Josef. The synthesis and characterization of N-(diphenylthiophosphinyl)-P-phenyl-thiophosphonamidic acid phenyl ester and related compounds chiral at phosphorus (The synthesis and characterization of N-(diphenylthiophosphinyl)-P-phenyl-thiophosphonamidic acid phenyl ester and related compounds chiral at phosphorus). Inorganic Chemistry Communications, Netherlands : Elsevier Science, 4, 1, p. 36-40. ISSN 1387-7003. 2001.

154. Novoměstská, Věra - Herrmann, Eckhard - Lubal, Přemysl - Příhoda, Jiří. Syntheses of new triethylene glycol bis(alkyl phosphate)s as potential complexing agents (Syntheses of new triethylene glycol bis(alkyl phosphate)s as potential complexing agents) Collect

Czech. Chem. Commun., Prague, 2001, Vol.66, p. 621-630. ISSN 0010 0765. 2001.

155. Novotný, J. - Petru�elka, J. - Pecen, L. - Svobodník, Adam - Du�ek, L. Matematické modelování rizika vzniku karcinomu prsu (Mathematical modelling of breast carcinoma risks). In Vybrané otázky onkologie. V. Praha : Nakladatelství Galén, 2001., p. 89-90.

156. Novotný, Karel - Stuchlíková, Věra - Otruba, Vítězslav - Kanický, Viktor. Mo�nosti vyu�ití UV laseru pro ablaci ocelí ve spojení s ICP-AES spektrometrií (Possible usage of UV-laser for ablation of steels coupled with ICP-AES spectrometry). In Hutní analytika 2001. Český Tě�ín : 2 THETA, 2001., p. 63-68. ISBN 80-86380-06-8.

157. Nováková, Soňa - Glatz, Zdeněk. Determination of the Kinetic Parameters of Rhodanese by Electrophoretically Mediated Microanalysis in a Partially Filled Capillary (Determination of the Kinetic Parameters of Rhodanese by Electrophoretically Mediated Microanalysis in a Partially Filled Capillary). In Book of abstract 2nd International symposium "Separations in BioSciences SBS 2001". Prague : Czech Chemical Society, 2001., p. 112-112. ISBN 80-7080-437-8.

158. Nováková, Soňa - Glatz, Zdeněk. Stanovení kinetických parametrů rhodanasy pomoci metody EMMA (Electrophoretivally Mediated Microanalysis) (Determination of the Kinetical Parameters of Rhodanese by Electrophoretivally Mediated Microanalysis). In Sborník příspěvků 5.Pracovního setkání biochemiků a molekulárních biologů. Brno : Přírodovědecká fakulta MU v Brně, 2001., p. 48-48. ISBN 80-210-2538-7.

159. Osman, Hanan - Mike�, Vladimír - Milat, Marie Louise - Ponchet, Michel. Fatty Acids Bind to the Fungal Elicitor Cryptogein and Competewith Sterols (Fatty Acids Bind to the Fungal Elicitor Cryptogein and Competewith Sterols). FEBS Letters, Amsterdam : Elsevier, 2001, 489, p. 55-58. ISSN 0014-5793. 2001.

160. Osman, Hanan - Mike�, Vladimír - Vauthrin, Sebastien - Milat, ML. Mediation of elicitin activity on tobacco is assumed by elicitin-sterol complex (Mediation of elicitin activity on tobacco is assumed by elicitin-sterol complex). Molecular Biology of the Cell, New York : America Society for Cell Biology, 2001, 12, p. 2825-2834. 2001.

161. Otruba, Vítězslav. Spektrometrie s indukčně vázaným plazmatem (ICP Spectrometry). Brno : Spektroskopická společnost Jana Marka Marci, 2001. ISBN 80-210-2713-4.

162. Pacheco Hernández, Maria De Lourdes - Havel, Josef. CAPILLARY ZONE ELECTROPHORETIC (CZE) STUDY OF URANIUM(VI) COMPLEXATION WITH HUMIC ACIDS (CAPILLARY ZONE ELECTROPHORETIC (CZE) STUDY OF URANIUM(VI) COMPLEXATION WITH HUMIC ACIDS). J. Radioanal. Nuclear Chemistry, 248, 3, p. 565-570-569. 2001.

163. Paleček, Emil - Fojta, Miroslav - Jelen, Franti�ek - Brázdová, Marie - Trnková, Libu�e. Electrochemistry of nucleic acids and proteins. Sensors for DNA hybridization and DNA damage. (Electrochemistry of nucleic acids and proteins. Sensors for DNA hybridization and DNA damage.). In 2nd Croatian symposium on electrochemistry, Proceedings. Primosten : Croatian Society of Chemical Ingineers, 2001., p. 1-7.

164. Palíková, M. - Navrátil, S. - Mar�álek, Blahoslav. Toxicita microcystinu pro embrya kapra obecného (Cyprinus carpio, L.) (Toxicity of microcystin to embryos of common carp). In Sborník referátů konference Toxicita a biodegradabilita odpadů a látek významných ve vodním prostředí. Praha : Ecomonitor s.r.o., 2001., p. 101-105.

165. Pavelka, Stanislav. Accumulation of iodide in rat thyroid and skin is reduced by high bromide intake. In Industrial Toxicology '2001 (Romančík V., ed.). Bratislava : Slovak Society for Industrial Chemistry, 2001., p. 212-216. ISBN 80-968011-5-5.

166. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav - Lener, Jaroslav. Effect of high bromide levels in the organism on the biological half-life of iodine in the rat. Biol. Trace Elem. Res., Totowa, NJ, USA : Humana Press, Inc., 82, 1-3, p. 125-132. ISSN 0163-4984. 2001.

167. Pavelka, Stanislav. Effects of exogenous bromide on iodine metabolism in the rat: An overview. In Industrial Toxicology '2001 (Romančík V., ed.). Bratislava : Slovak Society for Industrial Chemistry, 2001., p. 138-144. ISBN 80-968011-5-5.

168. Pavelka, Stanislav - Babický, Arno�t - Lener, Jaroslav - Vobecký, Miloslav. Effects of high bromide intake in the lactating rat on iodide accumulation in the mammary glands and its transfer to the sucklings. In Proceedings of the Vth Workshop of Biochemists and Molecular Biologists. Brno : Masaryk University, 2001., p. 38-39. ISBN 80-210-2538-7.

169. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav - Lener, Jaroslav. High bromide intake affects the accumulation of iodide in the rat thyroid and skin. Biol. Trace Elem. Res., Totowa, NJ, USA : Humana Press, Inc., 82, 1-3, p. 133-142. ISSN 0163-4984. 2001.

170. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav - Lener, Jaroslav. High bromide intake in the rat dam reduces iodine transfer to the sucklings. In Industrial Toxicology '2001 (Romančík V., ed.). Bratislava : Slovak Society for Industrial Chemistry, 2001., p. 217-222. ISBN 80-968011-5-5.

171. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav. High bromide intake in the rat changes the kinetics of iodide uptake and elimination by the thyroid and skin. In Sborník XVI. Biologických dnů "Aktuální témata z buněčné a molekulární biologie". Olomouc : Univerzita Palackého v Olomouci, 2001., p. 125-125. ISBN 80-244-0327-7.

172. Pavelka, Stanislav. Interference of exogenous bromide with iodine metabolism in the rat. In Sborník XVI. Biologických dnů "Aktuální témata z buněčné a molekulární biologie". Olomouc : Univerzita Palackého v Olomouci, 2001., p. 124-124. ISBN 80-244-0327-7.

173. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav - Lener, Jaroslav. Kinetics of accumulation of iodide in rat thyroid and skin is influenced by high bromide intake. In Proceedings of the Vth Workshop of Biochemists and Molecular Biologists. Brno : Masaryk University, 2001., p. 37-38. ISBN 80-210-2538-7.

174. Pavelka, Stanislav - Babický, Arno�t - Vobecký, Miloslav. Transfer of iodine through mother's milk is influenced by high bromide intake in the rat dam. In Sborník XVI. Biologických dnů "Aktuální témata z buněčné a molekulární biologie". Olomouc : Univerzita Palackého v Olomouci, 2001., p. 126-126. ISBN 80-244-0327-7.

175. Pazdera, Pavel. Syntéza nových heterocyklů s vyu�itím 1H-isochromenového prekurzoru (Synthesis of new fused heterocycles via 1H-isochromene precursor application). In XXV. Konference organických chemiků. 1. vyd. Pardubice : Univerzita Pardubice, 2001., p. KS 04-0. ISBN 80-7194-349-5.

176. Pazdera, Pavel - Vytiska, Zdeněk - Richter, Luká�. Three-component Domino-reaction of Diaminomaleodinitrile (Three-component Domino-reaction of Diaminomaleodinitrile). In 53. zjazd chemických spoločností. Banská Bystrica, Slovensko : FPV, Univerzita Mateja Bela v Banské Bystrici, 2001., p. 145-146. Zborník príspevkov. ISBN 80-89029-24-8.

177. Pazourek, Jiří - Polá�ková, Pavla - Havel, Josef - Reichová, Naďa. Separation and Determination of Adamantane Derivatives Possesing Antiviral Activity by Capillary Zone Electrophoresis (Separation and Determination of Adamantane Derivatives Possesing Antiviral Activity by Capillary Zone Electrophoresis). In ICES 2001, Glaxosmithkline Congress Center. Itálie : University of Verona, 2001., p. 50-50. - URL

178. Pazourek, Jiří - Polá�ková, Pavla - Havel, Josef - Dobiá�ová, Zuzana. Simultaneous Determination of trans-Resveratrol and Sorbic Acid in Wine by Capillary Zone Electrophoresis (Simultaneous Determination of trans-Resveratrol and Sorbic Acid in Wine by Capillary Zone Electrophoresis). In ICES 2001, Glaxosmithkline Congress Center. Itálie : University of Verona, 2001., p. 44-44. - URL

179. Pazourek, Jiří - Perrin, Catherine - Massart, Dessire-Luc - Havel, Josef. Validation of Chiral Separations in Capillary Zone Electrophoresis (Validation of Chiral Separations in Capillary Zone Electrophoresis). In ITP 2000, Book of abstracts, Bratislava, Slovakia. Slovensko : University of Bratislava, 2001., p. 50-50.

180. Pelliccioli, Anna Paola - Klán, Petr - Zabadal, Miroslav - Wirz, Jakob. Photorelease of HCl from o-Methylphenacyl Chloride Proceeds through the Z-Xylylenol. The Journal of the American Chemical Society, Washington, D.C. : American Chemical Society, 123, 32, p. 7931-7932. ISSN 0002-7863. 2001.

181. Petrová, Pavla - Monteiro, Celine - Herve du Penhoat, Catherine - Koča, Jaroslav - Imberty, Anne. Conformational behavior of nucleotide-sugar in solution: Molecular dynamics and NMR study of solvated uridinediphosphate-glucose in the presence of monovalent cations. Biopolymers, John Wiley & Sons, Inc, 58, 7, p. 617-635. 2001.

182. Picha, Radim - Bur�ík, Jiří - Bro�, Pavel. Phase structure study of Ni-Al-Cr-W and Ni-Al-Cr-Co alloys (Phase structure study of Ni-Al-Cr-W and Ni-Al-Cr-Co alloys). In JUNIORMAT '01. Brno : Ústav materiálového in�enýrství F. Pí�ka VUT FSI v Brně a Česká společnost pro nové materiály a technologie, 2001., p. 31-34. aluminium, chromium, cobalt, nickel, tungsten, phase diagram, thermodynamics, microstrucrure. ISBN 80-214-1885-0.

183. Picha, Radim - Bur�ík, Jiří - Bro�, Pavel. Study of phase equilibria in Al-Cr-Ni-W and Al-Cr-Ni-Co alloys (Study of phase equilibria in Al-Cr-Ni-W and Al-Cr-Ni-Co alloys). In 10th Annual Conference of Doctoral Students WDS'01 "WEEK OF DOCTORAL STUDENTS 2001". Prague : Faculty of Mathematics and Physics, Charles University, 2001., p. 561-565. Part III (Physics). ISBN 80-85863-73-1.

184. Pinkas, Jiří - Brlejová, Zuzana - Chromá, Markéta - Löbl, Jiří - Roesky, Herbert W. Nonaqueous Routes to Oxide Materials. In Zborník IV. seminára Príprava keramických materiálov. 1. vydanie. Ko�ice, Slovensko : Katedra chémie, Hutnícka fakulta TU v Ko�iciach, 2001., p. 103-106. ISBN 80-7099-660-9.

185. Pokorná, Lenka - Gajdo�ová, Dagmar - Mikeska, Stanislav - Homoláč, Pavel - Havel, Josef. The stability of humic acids in alkaline media. (The stability of humic acids in alkaline media.). Cambridge : RSC, 2001. 17 pp. Humic substances. ISBN 0-85404-811-1.

186. Potáček, Milan - Pospí�il, Jiří. Intramolecular 1,3-Dipolar Cycloaddition Initiated by Microwaves (Intramolecular 1,3-Dipolar Cycloaddition Initiated by Microwaves). In Proceedings - 18th International Congres of Heterocyclic Chemistry. 1. vyd. Yokohama : Graduate School of Pharmaceutical Sciences, University of Tokyo, 2001., p. 478-478.

187. Proke�, Lubomír - Otruba, Vítězslav - Kanický, Viktor. ICP-AES analýza kosterních pozůstaků z archeologických výzkumů (ICP-AES analysis of skeletal remains of archeological research). In Anorganická analýza v �ivotním prostředí. 1. vyd. Český Tě�ín : 2 THETA, 2001., p. 32-40. ISBN 80-86380-09-2.

188. Prokop, Zbyněk - Holoubek, Ivan. The use of a microbial contact toxicity test for evaluating cadmium bioavailability in soil (The use of a microbial contact toxicity test for evaluating cadmium bioavailability in soil). J. Soils and Sediments, 1, 1, p. 21-24. 2001.

189. Raiteri, Roberto - Grattarola, Massimo - Butt, Hans-Jurgen - Skládal, Petr. Micromechanical cantilever-based biosensors (Micromechanical cantilever-based biosensors). Sensors and Actuators B Chemical, Amsterdam (Holandsko) : Elsevier, 79, 2, p. 115-126. ISSN 0925-4005. 2001.

190. Sečkářová, Pavlína - Tou�ek, Jaromír - Dommisse, Roger - Dostál, Jiří - Marek, Radek. Free Bases of Benzophenanthridine Alkaloids - a Combined NMR, X-Ray and Theoretical Study. In 42nd Experimental NMR conference. Orlando (USA) : Inmerge, 2001., p. 235-235. 42nd ENC. - URL

191. Sečkářová, Pavlína - Man, Stanislav - Dostál, Jiří - Dommisse, Roger - Marek, Radek. NMR study of berberine and coptisine free bases. Chemické listy, Prague : Česká společnost chemická, 95, 11, p. 766-766. ISSN 0009-2770. 2001.

192. Sečkářová, Pavlína - Dostál, Jiří - Dommisse, Roger - Marek, Radek. Structure Elucidation of Benzophenanthridine and Protoberberine Alkaloids. In 16th NMR Valtice - Meeting of Central European NMR Discussion Groups. 1. vyd. Brno : Masaryk University, 2001., p. 19-19. 16th NMR Valtice. ISBN 80-210-2566-2.

193. Sitková, Pavla - Koča, Jaroslav - Imberty, Anne. Molecular dynamics simulations of solvated UDP-glucose in interaction with Mg cations. European Journal of Biochemistry, 268, 1, p. 5365-5374. 2001.

194. Skřičková, J. - Pálková, I. - �pelda, S. - Kaplanová, J. - Kubová, O. - Du�ek, L. - Koptíková, Jana - Merta, Z. Combined chemotherapy with ifosfamide in treatment of small cell lung cancer. (Combined chemotherapy with ifosfamide in treatment of small cell lung cancer.). In Lung Cancer - Current Topics. Bologna, Italy : Mondzuni Editore S.p.A. - MEDIMOND Inc., 2001., p. 209-213.

195. Slanina, Jiří - Táborská, Eva - Bochořáková, Hana - Slaninová, Iva - Humpa, Otakar - Robinson, W. Edward - Schram, Karl H. New and facile method of preparation of the anti-HIV-1 agent, 1,3-dicaffeoylquinic acid. Tetrahedron Letters, Oxford : Pergamon - Elsevier Science, 42, 19, p. 3383-6767. ISSN 0040-4039. 2001.

196. Slanina, Jiří - Táborská, Eva - Bochořáková, Hana - Slaninová, Iva - Humpa, Otakar - Robinson, W. Edward - Schram, Karl H. New and facile method of preparation of the anti-HIV-1 agent 1 3-dicaffeoylquinic acid Tetrahedron Letters Oxford : Pergamon - Elsevier

Science, 42, 19, p. 3383-6767. ISSN 0040-4039. 2001.

197. Smr�ová, Jana - Dvořák, Z. - Lata, J. - Dítě, Petr - Machala, M. - Bláha, L. - �imánek, V. - Ulrichová, J. Optimisation of porcine hepatocyte cryopreservation by comparison of viability and enzymatic activity of fresh and cryopreserved cells (Optimisation of porcine hepatocyte cryopreservation by comparison of viability and enzymatic activity of fresh and cryopreserved cells). Acta veterinaria (Brno), Brno, 70, 2, p. 141-147. ISSN 0001-7213. 2001.

198. Sopou�ek, Jiří - Million, Bořivoj - Vře�ťál, Jan. Computer Simulation of Up-hill Diffusion in CSN 17 242/P91 Welded Joint. In Seminar on Thermodynamics of Materials. Brno : Masaryk University, 2001., p. 79-82. ISBN 80-210-2709-9.

199. Sopou�ek, Jiří - Vře�ťál, Jan - Million, Bořivoj. Experimental and CalculatedCarbon Redistribution in Steel Weldment. In CALPHAD Meeting XXX. York (UK) : CALPHAD, 2001., p. 42-42.

200. Soto-Guerrero, Julio Arturo - Gajdo�ová, Dagmar - Havel, Josef. Uranium Oxide Clusters by Laser Desorption Ionisation During MALDI-TOF MS Analysis of Uranium(VI) (Uranium Oxide Clusters by Laser Desorption Ionisation During MALDI-TOF MS Analysis of Uranium(VI)). Journal of Radioanalytical and Nuclear Chemistry, 1, 249, p. 139-143. 2001.

201. Svoboda, Milan - Sopou�ek, Jiří - Vře�ťál, Jan. Structure of Superaustenitic Steels After Long-term Annealing (Structure of Superaustenitic Steels After Long-term Annealing). In Seminar on Thermodynamics of Materials. 1. vyd. Brno : Masaryk University in Brno, 2001., p. 83-86. ISBN 80-210-2702-9.

202. Svobodník, A. - Abrahámová, J. - Kubala, E. - Du�ek, L - Foretová, L. - Vyzula, R. - Smékal, V. - �aloudík, J. Predikce rizika vzniku karcinomu prsu u �en v České republice - metodika sběru dat pro validaci matematického prediktivního modelu (Prediction of breast cancer risk in the Czech Republic - methods of data collection for validation of the mathematic predictive model). Klinická Onkologie, Brno : ApS, s.r.o., 4, 1, p. 135-141. ISSN 8662-495X. 2001.

203. Svobodník, A. - Du�ek, L. - Abrahámová, J. - Kubala, E. - Petru�elka, L. - Novotný, J. - Pecen, L. - �aloudík, J. Projekt CARMEN - iniciativa v oblasti výzkumu, edukace a prevence karcinomu prsu (Project CARMEN - initiatives in research, education and prevention of breast carcinoma). In Vybrané otázky onkologie. V. Praha : Nakladatelství Galén, 2001., p. 86-88.

204. �atalov, V. - Malenichev, A. - Vulykh, N. - Berg, T. - Mano, S. - Holoubek, I. - Milukaite, A.-R. - Afinogenova, O. Assessment of POP transport and accumulation in the environment. (Assessment of POP transport and accumulation in the environment.). Moscow : EMEP Report 4/2001, 2001. 131 pp.

205. �erý, Omar - Znojil, Vladimír - Popov, Petr - �imek, Vladimír - Mike�, Vladimír - Zvolský, Petr. Alkoholizmus a angiotensinkonvertáza - předbě�né výsledky asociační studie (Alcoholism and angiotensin converting enzyme - preliminary results of the association study). Psychiatrie, Praha : TIGIS, 5, Suppl. 1, p. 32-32. ISSN 1211-7579. 2001.

206. �erý, Omar - Znojil, Vladimír - Popov, Petr - �imek, Vladimír - Mike�, Vladimír - Zvolský, Petr. Alkoholizmus a angiotensinkonvertáza - předbě�né výsledky asociační studie (Alcoholism and ACE - preliminary results of the association study). Psychiatrie, Praha : TIGIS, 5, Suppl. 1, p. 32-32. ISSN 1211-7579. 2001.

207. �erý, Omar - Mike�, Vladimír - Ka�parovská, Jitka - Hladilová, Renáta - �imek, Vladimír - Znojil, Vladimír - Gláslová, Kateřina - Profous, Jiří - Zvolský, Petr. Alkoholizmus a dopaminový receptor D2 - předbě�né výsledky asociační studie (Alcoholism and DRD2 receptor - preliminary results of the association study). Psychiatrie, Praha : TIGIS, 5, Suppl. 1, p. 32-32. ISSN 1211-7579. 2001.

208. �erý, Omar - Mike�, Vladimír - Ka�parovská, Jitka - Hladilová, Renáta - �imek, Vladimír - Znojil, Vladimír - Gláslová, Kateřina - Profous, Jiří - Zvolský, Petr. Alkoholizmus a dopaminový receptor D2 - předbě�né výsledky asociační studie (Alcoholism and DRD2 - preliminary results of the association study). Psychiatrie, Praha : Tigis, 5, Suppl. 1, p. 32-32. ISSN 1211-7579. 2001.

209. �erý, Omar - Hladilová, Renáta - Ka�parovská, Jitka - Mike�, Vladimír - �imek, Vladimír - Novotný, Miroslav - Vojtová, Veronika - Zvolský, Petr. Ovlivňuje polymorfizmus TaqI A DRD2 dispozice k alkoholizmu? (Does the TaqI A DRD2 polymorphism affect the disposition to the alcoholism?). In V. Pracovní setkaní biochemiků a molekulárních biologů. První vydání. Brno : Masarykova Univerzita, 2001., p. 20-20. 1. ISBN 80-210-2538-7.

210. �evčíková, Petra - �těrbová, Hana - Glatz, Zdeněk - Slanina, Jiří - Musil, Pavel. Application of micellar electrokinetic capillary chromatography for the analysis of schizandra extract (Application of micellar electrokinetic capillary chromatography for the analysis of schizandra extract). In Book of abstract ICES 2001 An Electrophoretic Odessey. 1. vyd. Verona : Emmezeta Congressi, 2001., p. 80-80.

211. �evčíková, Petra - Glatz, Zdeněk - Slanina, Jiří - Musil, Pavel. Determination of phenolic compounds in artichoke extract by means of MEKC (Determination of phenolic compounds in artichoke extract by means of MEKC). In Book of abstract ICES 2001 An Electrophoretic Odessey. 1. vyd. Verona : Emmezeta Congressi, 2001., p. 80-80.

212. �evčíková, Petra - Glatz, Zdeněk. Monitoring of Dithiothreitol Clearance by Micellar Electrokinetic Chromatography (Monitoring of Dithiothreitol Clearance by Micellar Electrokinetic Chromatography). In Book of abstract 2nd International symposium "Separations in BioSciences SBS 2001". Prague : Czech Chemical Society, 2001., p. 86-86. ISBN 80-7080-437-8.

213. �evčíková, Petra - �těrbová, Hana - Glatz, Zdeněk - Slanina, Jiří - Musil, Pavel. Vyu�ití micelární elektrokinetické kapilární chromatografie pro analýzu extraktu schizandry činské (Application of Micellar Electrokinetic Chromatography for the Analysis of Schisandra Extract). In Sborník příspěvků 5.Pracovního setkání biochemiků a molekulárních biologů. Brno : Přírodovědecká fakulta MU v Brně, 2001., p. 49-49. ISBN 80-210-2538-7.

214. �tefl, Richard - Trantírek, Luká� - Vorlíčková, Michaela - Koča, Jaroslav - Sklenář, Vladimír - Kypr, Jaroslav. A-like Guanine-Guanine Stacking in the Aqueous DNA (A-like Guanine-Guanine Stacking in the Aqueous DNA). Journal of Molecular Biology, USA : Academic Press, 307, 1, p. 513-524. ISSN 0022-2836. 2001.

215. �tefl, Richard - �pačková, Nadě�da - Berger, Imre - Koča, Jaroslav - �poner, Jiří. Molecular dynamics of DNA quadruplex molecules containing inosine, 6-thioguanine and 6-thiopurine. Biophysical Journal, Bethesda, USA : Biophysical Society, 80, 1, p. 455-468. ISSN 0006-3495. 2001.

216. �tefl Richard - �pačková Naďa - Berger Imre - Koča Jaroslav - �poner Jiří Molecular Dynamics of DNA Quadruplex Molecules

Containing Inosine, 6-Thioguanine and 6-Thiopurine. Biophysical Journal, New York, USA : Rockefeller University, 80, 1, p. 455-468. ISSN 0006-3465. 2001.

217. �těpán, Martin - Semerád, Martin - Kanický, Viktor - Otruba, Vítězslav. Preliminary investigations of high-frequency atmospheric-pressure plasma jet for atomic emission spectrometry. Collection of Czechoslovak Chemical Communications, Prague : Inst. Org. Chem. Biochem. Acad. Sci. CR, 66, 9, p. 1348-1358. ISSN 0010-0765. 2001.

218. �těpánková, Romana - Hrdlička, Ale� - Sommer, Lumír. HPLC separace chlorfenolů na koloně malého průměru pro stanovení v povrchových vodách (HPLC Separation of Chlorophenols on Narrow-Bore Column for Their Determination in River Water). In Sborník 53. Zjazdu chemických spoločností. Banská Bystrica : SChS, 2001., p. 48-49. Sborník 2. ISBN 80-89029-23.

219. Tomi�ka, Miroslav - Adam, Zdeněk - Proke�, Boleslav - Du�ek, Ladislav - Hájek, Roman - Vorlíček, Jiří. Bone Mineral Density in Multiple Myeloma Patients after Intravenouc Clodronate Therapy (Bone Mineral Density in Multiple Myeloma Patients after Intravenouc Clodronate Therapy). Acta Medica Austriace, Austria, 2, 1, p. 38-42-42. ISSN 0303-8173. 2001.

220. Tou�ek, Jaromír - Marek, Radek - Brus, Jiří - Kovács, Lajos - Hocková, Dana. Theoretical Study of 15N Chemical Shielding Tensors of N7 and N9 Substituted Purine Derivatives (Theoretical Study of 15N Chemical Shielding Tensors of N7 and N9 Substituted Purine Derivatives). Chem. Listy, Praha : Česká společnost chemická, 95, 11, p. 770-770. ISSN 0009-2770. 2001.

221. Trantírek, Luká� - Hynková, Kamila - Nagata, Yuji - Murzin, Alexey - Ansorgová, Alena - Sklenář, Vladimír - Damborský, Jiří. Reaction mechanism and stereochemistry of gamma-hexachlorocyclohexane dehydrochlorinase LinA (Reaction mechanism and stereochemistry of gamma-hexachlorocyclohexane dehydrochlorinase LinA). The Journal of Biological Chemistry, 276, 11, p. 7734-7740. 2001. - URL

222. Trnková, Libu�e - Kizek, René - Paleček, Emil. Electrochemical investigation of rabbit liver metallothionein at a mercury electrode (Electrochemical investigation of rabbit liver metallothionein at a mercury electrode). In XVIth International Symposium on Bioelectrochemistry and Bioenergetics. Bratislava, Slovakia : Comenius University, Bratislava, Slovakia, 2001., p. 25-25. BEB.

223. Trnková, Libu�e. Elektrochemické eliminační metody (Electrochemical Elimination Methods). CHEMICKÉ LISTY, Praha : Česká společnost chemická, 95, 9, p. 518-527. ISSN 0009-2770. 2001.

224. Trnková, Libu�e - Friml, Jiří - Dračka, Oldřich. Elimination Voltammetry of Adenine and Cytosine Mixtures (Elimination Voltammetry of Adenine and Cytosine Mixtures). Bioelectrochemistry, The Netherlands : Elsevier, 2001, 54, p. 131-136. ISSN 1567-5394. 2001.

225. Trnková, Libu�e - Kizek, René - Dračka, Oldřich. Elimination voltammetry of nucleic acids on silver electrodes (Elimination voltammetry of nucleic acids on silver electrodes). In XVIth International Symposium on Bioelectrochemistry and Bioenergetics. Bratislava, Slovensko : Comenius University, Bratislava, Slovensko, 2001., p. 101-101. BEB.

226. Trnková, Libu�e - Postbieglová, Irena - Kizek, René - Jelen, Franti�ek. Kombinace adsorptivní přenosové rozpou�těcí voltametrie a eliminační voltametrie (Combination of adsorptive transfer stripping voltammetry and elimination voltammetry). In Moderní elektrochemické metody. Ústí nad Labem : SES Logis s ÚFCH J.H., 2001., p. 12-12. Moderní elektrochemické metody.

227. Trnková, Libu�e. Studium elektrodového procesu pomocí eliminačních metod (Study of electrode process by elimination methods). In Moderní elektrochemické metody. Ústí nad Labem s ÚFCH J.H.v Praze : SES Logis, 2001., p. 11-11. Moderní elektrochemické metody.

228. Trávníček, Martin - Potáček, Milan. Regioselektivita a vliv chirální pomocné látky vázané na dipolu na enantioselektivitu 1,3-dipolární cykloadice (Regioselectivity and influence of chiral auxiliary bound on dipol upon enantioselectivity of 1,3-dipolar cycloaddition). In Sborník XXV. Konference organických chemiků. 1. vyd. Pardubice : Univerzita Pardubice, 2001., p. KS11-1. XXV. Konference organických chemiků, Kutná Hora. ISBN 80-7194-349-5.

229. Trávníček, Martin - Potáček, Milan - Mannschreck, Albrecht. Stereochemistry of 1,3-dipolar Cycloaddition Reaction of Azomethine Ylides Derived from N-alkyl-N-(4-toluenesulfonyl)carbamoylmethyl phenanthridinium with Olefinic Dipolarophiles. (Stereochemistry of 1,3-dipolar Cycloaddition Reaction of Azomethine Ylides Derived from N-alkyl-N-(4-toluenesulfonyl)carbamoylmethyl phenanthridinium with Olefinic Dipolarophiles.). Heterocyclic Communications, London : Freund Publishing House, 2001, 3, p. 213-222. ISSN 0793-0283. 2001.

230. Turánek, Jaroslav - Záluská, Dana - Vacek, Antonín - Borkovcová, Petra - Thurnvaldová, Jitka - Bláha, Luděk - Ma�ek, Kare. Stimulation of nonspecific immunity, haemopoiesis and protection of mice against radiation injury by 1-adamntylamide-L-alanyl-D-isoglutamine incorporated in liposomes (Stimulation of nonspecific immunity, haemopoiesis and protection of mice against radiation injury by 1-adamntylamide-L-alanyl-D-isoglutamine incorporated in liposomes). International Immunopharmacology, Amsterdam, Netherlands : Elsevier, 1, 1, p. 167-175. 2001.

231. Vondráček, Jan - �tika, Jiří - Souček, Karel - Minksová, Kateřina - Bláha, Luděk - Hofmanová, Jiřina - Kozubík, Alois. Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells. European Journal of Pharmacology, Amsterdam : Elsevier Science B.V., 424, 1, p. 1-11. ISSN 0014-2999. 2001.

232. Vondráček, Jan - Machala, Miroslav - Minksová, Kateřina - Bláha, Luděk - Murk, A.J. - Kozubík, Alois - Hofmanová, Jiřina - Hilscherová, Klára - Ulrich, Robert - Ciganek, Miroslav - Neča, Jiří - �vrčková, Daniela - Holoubek, Ivan. Monitoring river sediments contaminated predominantly with polyaromatic hydrocarbons by chemical and in vitro bioassay techniques (Monitoring river sediments contaminated predominantly with polyaromatic hydrocarbons by chemical and in vitro bioassay techniques). Environmental Toxicology and Chemistry, Pensacola, FL, USA : SETAC, 20, 7, p. 1499-1506. ISSN 0730-7268. 2001.

233. Vyzula, Rostislav - �aloudík, Jan - Du�ek, Ladislav - Vermousek, I. Seasonal variation in estrogen and progesterone receptor levels in breast cancer - a factor in data interpretation (Seasonal variation in estrogen and progesterone receptor levels in breast cancer - a factor in data interpretation). Neoplasma, 48, 1, p. 1-1. ISSN 0028-2685. 2001.

234. Váňa, M. - Holoubek, I. - Pacl, A. - Pekárek, J. - Smrčková, V. - Machálek, P. - Hele�ic, Jan - �eda, Zdeněk - Adamec, V. - Janouch, M. - Honzák, J. - Ansorgová, Alena - Kohoutek, Jiří - Holoubková, Irena - Shatalov, V. - Dutchak, Sergej - Fottová, D. - Hru�ka, J. - Hofman, Jakub - Anděl, Petr. Quality of the natural environment in the Czech Republic at the regional level. Results of the Ko�etice Observatory (Quality of the natural environment in the Czech Republic at the regional level Results of the Ko�etice Observatory)

Praha : ČHMÚ Praha, 2001. 189 pp. ISBN 80-85813-88-2.

235. Vít, Jan - Sopou�ek, Jiří - Vře�ťál, Jan. Prediction of Phase Diagram Cross-Section of the Fe-Cr-Ni-Mo-Mn-N Based System. In TRANSCOM 2001. �ilina, Slovak Rep. : University of �ilina, 2001., p. 133-136.

236. Vře�ťál, Jan - Houserová, Jana - Friák, Martin - �ob, Mojmír. Application of first-principles calculations in phase diagram calculations. In Thermodynamics of Materials. Brno : Masaryk University, 2001., p. 61-65. Proc. of the Seminar on Thermodynamics of Material. ISBN 80-210-2702-9.

237. Vře�ťál, Jan. First-principles Calculations Results in Phase Diagram Construction (First-principles Calculations Results in Phase Diagram Construction). Journal of Mining and Metallurgy, Bor, Yugoslavia : Technical Faculty University of Belgrade, 37, 3-4, p. 29-40. ISSN 1450-5339. 2001.

238. Vře�ťál, Jan. Recent progres in modelling of sigma-phase (Recent progres in modelling of sigma-phase). Archives of Metallurgy, Krakow : Polish Acad.Sci.Comm.Metallurgy,Krakow, 46, 3, p. 239-247. ISSN 0860-7052. 2001.

239. Yamanaka, Hideko - Skládal, Petr. Amperometric immunosensor for atrazine (Amperometric immunosensor for atrazine). Anais de Associacao Brasilian de Quimica, Sao Paulo : ABQ, 50, 1, p. 25-28. 2001.

240. Zabadal, Miroslav - Klán, Petr. Fotolabilní chránící skupiny (Photoremovable Protecting Groups). Chemické Listy, Praha : Česká společnost chemická, 95, 11, p. 694-699. ISSN 0009-2770. 2001.

241. Zabadal, Miroslav - Pelliccioli, Anna P. - Klán, Petr - Wirz, Jakob. 2,5-Dimethylphenacyl Esters: A Photoremovable Protecting Group for Carboxylic Acids. Journal of Physical Chemistry A, USA : The American Chemical Society, 105, 45, p. 10329-10333. ISSN 1089-5639. 2001.

242. Zeman, Josef. Dlouhodobá interakce atmosférického CO2 s karbonátovým vodným prostředím (Long term interaction of atmospheric CO2 with carbonate water environment). In Smolíková, Zdena. Geochémia 2001. Bratislava, Slovenská republika : PrirF UK, �GÚD�, 2001., p. 29-31. ISBN 80-88-974-33-X.

243. Zeman, Josef. Dynamická interakce sedimentů a vodného prostředí (Dynamic interaction of sediments and water environment). In Müllerová, Hana. Geochémia 2001. Bratislava, Slovenská republika : PrirF UK, �GÚD�, 2001., p. 32-34. ISBN 80-88-974-33-X.

244. Zeman, Josef. Statická a dynamická sorpce kadmia sedimenty (Cadmium static and dynamic sorption by sediments). In Vybíhal, Karel. Geochémia 2001. Bratislava, Slovenská republika : PrirF UK, �GÚD�, 2001., p. 35-37. Geochémia 2001. ISBN 80-88-974-33-X.

245. Zouhar, Jan - Vévodová, Jitka - Marek, Jaromír - Damborský, Jiří - Su, X.-D. - Brzobohatý, Břetislav. Insights into the Functional Architecture of the Catalytic Center of a Maize Beta-Glucosidase Zm-p60.1 (Insights into the Functional Architecture of the Catalytic Center of a Maize Beta-Glucosidase Zm-p60.1). Plant Physiology, USA : American Society of Plant Physiologists, 127, 3, p. 973-985. ISSN 0032-0889. 2001.

246. �aloudík, Jan - Du�ek, L. Flowcytometrický DNA profil nádorů - aplikace v klinické onkologii (Flowcytometry DNA profile of tumors - applications in the clinical oncology). In Sborník konference Analytická cytometrie I. Brno : BFU AV ČR, 2001., p. 15-16. ISBN 80-238-6833-0.

247. �ídek, Luká� - Wu, Haihong - Feigon, Juli - Sklenář, Vladimír. Measurement of small scalar and resiudal dipolar couplings in purine and pyrimidine bases (Measurement of small scalar and resiudal dipolar couplings in purine and pyrimidine bases). Journal of Biomolecular NMR, Dordrecht : Kluwer/Escom, 21, 2, p. 153-159. ISSN 0925-2738. 2001.

248. �ídek, Luká� - �tefl, Richard - Sklenář, Vladimír. NMR methodology for the study of nucleic acids (NMR methodology for the study of nucleic acids). Current Opinion in Structural Biology, London : Elsevier Science Ltd., 11, 3, p. 275-281. ISSN 0959-440X. 2001.

chemistry year Œ book 2001 - sci.muni.cz · chemistry year Œ book 2001 faculty of science masaryk...

Documents