Chemistry Notices

For the Week of March 28 to April 1, 2016

Submissions: Please send to newsletter@chem.ualberta.ca by Wednesday for the following week’s edition

EMPLOYMENT  OPPORTUNITIES  

Job Description

Scientist I, Chemistry-16000001C9

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following

separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people

and unique approach to innovation to develop and market advanced therapies that address some of the

world's most complex and serious diseases. AbbVie employs approximately 28,000 people worldwide

and markets medicines in more than 170 countries.

Description

Process Research and Development is responsible for inventing and executing the chemical processes

and preparing active pharmaceutical ingredient (API) to enable clinical trials, toxicology studies and drug

product development for Abbvie’s pre-clinical and clinical candidates. We create valuable intellectual

property through composition of matter, chemical processes, and technology resulting in a cost

effective commercial manufacturing process. We develop the supply chain for APIs, prepare and defend

CMC (Chemistry, Manufacturing and Control) regulatory content.

AbbVie is seeking a research chemist with strong laboratory skills to work in its Pressure and Catalysis

Group under the mentorship of a supervisor. The successful candidate will work on the discovery,

development, and execution of catalytic methods, particularly those requiring gas reactants or

operation above ambient pressure (e.g., hydrogenations), for the preparation of compounds to treat a

variety of diseases. The successful candidate will be an active participant in integrated Process Research

& Development project teams consisting of synthetic, structural, and analytical chemists and engineers

whose goal is to identify and develop novel practical routes to newly discovered therapeutic targets. The

ideal candidate will be enthusiastic and productive in the laboratory and have good written and verbal

communication skills.

Equal Opportunity Employer Minorities/Women/Veterans/Disabled

Qualifications

Level and compensation will be commensurate with experience.

Basic:

x A BS degree in chemistry or chemical engineering with 3 or more years of relevant job

experience or an MS degree chemistry or chemical engineering with 0 or more years of relevant

job experience.

x A commitment to safety.

x A passion for learning.

x Functional experience in modern synthetic organic chemistry, compound purification, and

organic chemistry mechanisms.

x Basic analytical chemistry skills (understanding, routine use, interpretation, and troubleshooting

of HPLC, LCMS, GC, and GCMS and the ability to perform basic NMR interpretation)

EMPLOYMENT  OPPORTUNITIES,  continued  

Apply online at : https://abbvie.taleo.net/careersection/2/jobdetail.ftl?job=16000001C9&lang=en

x A basic understanding of kinetics, thermodynamics. x Ability to search the chemical literature (e.g., using SciFinder). x Strong basic science and reasoning skills. The ability to plan, execute, critically interpret, and

track the results from a logical progression of experiments in order to efficiently obtain definitive results.

x Proven written and verbal communication skills; the ability to effectively communicate in a team setting.

x Mechanical aptitude. Experienced in the use of basic tools. Able to troubleshoot, maintain, and operate mechanical systems such as Parr pressure reactors.

x Willingness to work occasional nights and weekends when necessary. Key Leadership Competencies:

x Builds strong relationships with peers and cross functionally with partners outside of teams to enable higher performance.

x Learns fast, grasps the "essence" and can change course quickly where indicated. x Raises the bar and is never satisfied with the status quo. x Creates a learning environment, open to suggestions and experimentation for improvement. x Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Other helpful skills: Experience or proficiency in LabView or other computer language programming; data manipulation in Excel, DynoChem, KaleidaGraph, or related software; Design of Experiments (DoE); handling air-sensitive materials in a glovebox or using Schlenk techniques; and operating under cGMP. Significant Work Activities and Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day) Job Classification: Experienced Job: RESEARCH AND DEVELOPMENT Primary Location: USA-Illinois-Lake County Organization: GPRD-Pharma R&D Schedule: Full-time Shift: Morning Travel: Yes, 5 % of the Time

EMPLOYMENT  OPPORTUNITIES,  continued   AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 28,000 people worldwide and markets medicines in more than 170 countries. Description AbbVie is looking for a Scientist II, Chemistry with strong synthetic skills. This individual will work under the mentorship of a supervisor discovering, developing and executing routes to compounds to treat a variety of diseases. The candidate will be a member of an integrated Process Research & Development project team consisting of synthetic, structural, and analytical chemists and engineers whose goal is to identify and develop novel practical routes to newly discovered therapeutic targets. The ideal candidate will be enthusiastic and productive, with excellent communication skills and strong functional expertise in synthetic organic chemistry and compound synthesis and characterization. Equal Opportunity Employer Minorities/Women/Veterans/Disabled Qualifications Level and compensation will be commensurate with experience. Basic: • MS  degree  in  chemistry  with  2-­‐5  years  of  laboratory  experience  or  BS  degree  in  chemistry  with  5-­‐7  years  

laboratory  experience.    • Broad  range  of  functional  expertise  in  modern  synthetic  organic  chemistry,  compound  purification,  

spectral  analysis  and  interpretation.  • Ability  to  search  the  chemical  literature  to  ascertain  viable  approaches  to  synthetic  problems.  • Willingness  to  work  occasional  nights  and  weekends  when  necessary.  Preferred  Qualifications:  • Experience  doing  synthetic  method  development,  new  reaction  discovery,  study  of  reaction  mechanism  or  

total  synthesis  • Record  of  scientific  accomplishment  with  author  credit  in  peer-­‐reviewed  publications  • Ability  to  independently  lead  own  chemistry  research  and  effectively  function  in  a  goal-­‐oriented  team  

environment.  

Key Leadership Competencies: • Builds  strong  relationships  with  peers  and  cross  functionally  with  partners  outside  of  team    to  enable  

higher  performance.  • Learns  fast,  grasps  the  "essence"  and  can  change  course  quickly  where  indicated.  • Raises  the  bar  and  is  never  satisfied  with  the  status  quo.  • Creates  a  learning  environment,  open  to  suggestions  and  experimentation  for  improvement.  • Embraces  the  ideas  of  others,  nurtures  innovation  and  manages  innovation  to  reality.  

Significant Work Activities and Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day) Job Classification: Experienced Job: RESEARCH AND DEVELOPMENT Primary Location: USA-Illinois-Lake County Organization: GPRD-Pharma R&D Schedule: Full-time Shift: Morning Travel: Yes, 5 % of the Time Apply online at: https://abbvie.taleo.net/careersection/2/jobdetail.ftl?job=160000019Q&lang=en#.VulQA9x65QQ.mailto

EMPLOYMENT  OPPORTUNITIES,  continued  

Saskatchewan Structural Sciences Centre Rm. G81.1 Thorvaldson Building, 110 Science Place, Saskatoon, SK S7N 5C9

Telephone: (306) 966-4373 Email: R.Sammynaiken@usask.ca

RESEARCH OFFICER

(Spectroscopy and Microscopy) The Saskatchewan Structural Sciences Centre (SSSC) seeks applications from qualified scientists to fill a staff position in spectroscopy and microscopy. The SSSC an integrated multidisciplinary analytical facility located at the University of Saskatchewan. The SSSC trains undergraduate students, graduate students and other researchers in the operation of the analytical instruments and provides users with access to more than twenty major state of the art instruments. The Centre serves the University, public sector and private industry researchers in basic sciences and engineering, as well as fostering multidisciplinary collaborations in diverse fields, ranging from agriculture, to health sciences and Engineering. Nature of work:

This is a position that supports research in a multidisciplinary environment, requiring the ability to work as a member of a team and to deal with multiple demands from diverse users for expertise and delivery of service. The Research Officer will have primary responsibility for instructing researchers in theory, experimental methods for and technical aspects of microscopy and spectroscopy (1p-2p Confocal Microscopy, Fluorescence Lifetime Imaging Micrioscopy, Raman Microscopy, Electron Spin Resonance, Single Event Effect, Fluorescence Upconversion) and their associated technologies through hands on training, as well as development and delivery of short courses and tutorials. The Research Officer will provide instruction on technical aspects of spectromicroscopy and microscopy and instrument operation and will also be responsible for supervising users, implementing safety rules and helping non-experts process data. Under the direction of the Manager, the Research Officer will develop methods and design and fabricate prototype instruments to support microscopy and spectroscopy researchers using the SSSC. The Research Officer will be expected to conduct experiments to validate and develop new methods, to provide technical consultation and information for writing grants and conduct contract research (fee-for-service). Qualifications: The minimum requirements are a PhD in Physical Science or Engineering with expertise in analysis of hard or soft materials using advanced spectroscopic and microscopic techniques. Candidates with a M.Sc. or equivalent education and extensive experience will also be considered. Full Job profile can be found at http://jobs.usask.ca/job_postings/jobs/16148m.php#.Vub5B9CGEgs Salary: ASPA PHASE II ($59,517-$92,996) Review of applications will begin on April 12, 2016 and will be accepted until a suitable candidate is found. Only applications submitted via the University of Saskatchewan employment site will be accepted: http://jobs.usask.ca/job_postings/jobs/16148m.php#.Vub5B9CGEgs The University of Saskatchewan is committed to Employment Equity. Members of Designated Groups (women, aboriginal people, people with disabilities and visible minorities) are encouraged to self-identify on their applications.

EMPLOYMENT  OPPORTUNITIES,  continued    

Company:)) Trojan)Technologies)Job)Title:! Analytical!Chemist,!LCMS!!Department:! Research,!Advanced!Technology!Team!Job)Length:) 12<24!months,!Approx.)start)date:) July!1,!2016!Job)Location:! London,!Ontario!Preferred)Disciplines:! Chemistry,!Physical!Chemistry!!Trojan!Technologies!is!recognized!around!the!world!as!the!leader!of!advanced!ultraviolet!(UV)!water!treatment!technology.!Our!photoreactors!are!engineered!for!such!applications!as!the!disinfection!of!water!by!the!inactivation!of!pathogenic!microbial!species!and!the!destruction!of!toxic!contaminants!in!water!through!UV!photolysis!and!advanced!UV!oxidation!processes.!!

Trojan!Technologies!is!pursuing!opportunities!in!disinfecting!media!for!cell!culture!in!biopharmaceutical!production,!and!in!the!downstream!purification!of!biopharmaceutical!products.!These!fluids!are!complex!mixtures!of!amino!acids,!sugars,!vitamins!and!minerals,!and!UV!irradiation!can!cause!complex!photochemical!reactions!that!may!affect!the!concentration!of!essential!compounds!such!as!vitamins.!!

Position'Description'Reporting!directly!to!a!senior!Research!Scientist,!the!successful!candidate!will!develop!and!utilize!LCMS!and!GCMS!methods!to!quantify!low!concentrations!of!vitamins,!byproducts,!and!trace!contaminants!in!complex!aqueous!solutions.!

Key'Responsibilities'1. Chemical!Analysis!

a. Predicting!and!evaluating!UV<induced!chemical!changes!in!cell!culture!media!and!other! fluids! utilizing:! LC<MS/MS! with! SPE,! GCMS,! HPLC,! Fluorimetry,! UV<Vis!Spectrophotometry.!

b. Collecting!samples,!labeling,!tracking!c. Sample!preparation!through!SPE!and!other!methods!d. Irradiating!samples!using!laboratory!UV!devices!e. Devising!methods!to!mitigate!formation!of!unwanted!byproducts,!evaluating!the!

methods.!2. Data!Analysis!and!report!writing!

a. Collection!and!Statistical!analysis!of!data!b. Drafting!text!for!internal!and!external!publications!c. Literature!search!and!review!of!methods,!MRM!transitions,!etc.!

3. Assisting! in! general! lab! operation! and! instrument! maintenance,! chemical! inventory!management!and!MSDS,!lab!waste!management!etc.!

4. Collaborating!with!other!scientists!and!managers!)

EMPLOYMENT  OPPORTUNITIES,  continued    

Background'and'required'skills'The!ideal!candidate!will!have!a!PhD!in!Physical!Chemistry,!or!Chemical!Engineering!with!strong!

skills!in!mass!spectrometry,!liquid!chromatography!and!gas!chromatography.!!

1. Experience!with! analytical! techniques! including! ,! but! not! limited! to! LCMS/MS,!GCMS,!

UV<Vis,!HPLC,!SPE,!SPME!

2. Strong!verbal!and!written!communication!is!required!

3. Demonstrated!lab!experience!is!an!asset!

4. Knowledge!of!mammalian!cell!culture!and!antibody!production!is!an!asset!

5. Knowledge!of!1D<NMR!is!an!asset!

!

If!you!join!Trojan!Technologies!you!will!be!working!side<by<side!with!the!top!talent!in!the!fluid!

treatment!industry!who!have!fostered!the!growth!and!development!of!UV!photoreactor!

technology.!You!will!have!the!opportunity!to!work!alongside!PhD.!Scientists!and!Professional!

Engineers!and!gain!invaluable!practical!and!industrial!experience!working!in!a!fast<paced,!

progressive!and!technology<oriented!company.!

!

EMPLOYMENT  OPPORTUNITIES,  continued  The  following  is  a  2  year  funding  program  for  PDFs.  The  LOI  is  due  March  23,  2016  and  final  applications  are  due  April  6,  2016.    

ABOUTMITACS

ELEVATE

I’ve learned lab and project management skills that were never part of my formal academic training. I learned how to communicate better with industrial partners and to plan out larger-scale projects that I wouldn’t be able to accomplish alone in a purely academic setting. Thanks to these skills I learned in the Elevate program, I’m starting to coordinate large multidisciplinary projects involving clinicians, academics, and industrial partners – and that’s exactly where I wanted to be.”

“

Elevate is a one-of-a-kind program. Not only does it support scientific research, but personal and professional development is emphasized. Attending business and entrepreneurship workshops and seminars throughout my fellowship allowed me to see beyond the technical realm and grow my network, tenfold.”

“

Dr. Peter Bevan, Mitacs Elevate fellow

Dr. Aydin Nabovati, Mitacs Elevate fellow

Are you a postdoctoral fellow – or the faculty supervisor of one – seeking longer-term funding options?

Would you like to develop your research leadership skills with exclusive professional training valued at $15,000?

Do you want the opportunity to partner with a company to address a research challenge over two years?

Are you interested in learning how to manage large-scale research projects?

Mitacs Elevate offers postdoctoral fellows a two-year professional development plan and collaborative research project, building capacity for the next generation of R&D management leaders.

The program provides fellows with customized training that is only available from Elevate. Fellows explore topics such as project management, leadership, and presentation skills, while applying both their expertise and professional skill set to their partner organization. Fellows receive one to two days of training per month throughout their two-year research projects.

This engagement with organizations also provides Elevate fellows with the opportunity to work on a collaborative research challenge and gain valuable research leadership experience.

www.mitacs.ca

UNIVERSITY

[August 26, 2015]

EMPLOYMENT  OPPORTUNITIES,  continued    

OTHER  OPPORTUNITIES  

OTHER  OPPORTUNITIES,  continued