cheminform abstract: sna-8073-b, a new isotetracenone antibiotic inhibits prolyl endopeptidase. part...
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![Page 1: ChemInform Abstract: SNA-8073-B, a New Isotetracenone Antibiotic Inhibits Prolyl Endopeptidase. Part 1. Fermentation, Isolation and Biological Properties](https://reader030.vdocuments.mx/reader030/viewer/2022020508/575003541a28ab1148988938/html5/thumbnails/1.jpg)
1997 antibiotics
antibioticsU 1200
42 - 280SNA-8073-B, a New Isotetracenone Antibiotic Inhibits ProlylEndopeptidase. Part 1. Fermentation, Isolation and BiologicalProperties. — The title compound (I) inhibits prolyl endopeptidase ofFlavobacterium non-competitively (IC50=8.9 µM) when Z-Gly-Pro-pNA is usedas a substrate. — (KIMURA, K.; KANOU, F.; KOSHINO, H.; URAMOTO,M.; YOSHIHAMA, M.; J. Antibiot. 50 (1997) 4, 291-296; Res. Inst. LifeSci., Snow Brand Milk Prod. Co., Ltd., Shimotsuga, Tochigi 329-05, Japan; EN)
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