cheminform abstract: flavonoids from eupatorium odoratum with death receptor 5 promoter enhancing...

ChemInform 2009, 40, issue 28 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Other bioactive products U 1300 Flavonoids from Eupatorium Odoratum with Death Receptor 5 Promoter Enhancing Activity. — Two new flavonoids (I) are isolated from the leaves of Eupa- torium odoratum together with 14 known flavonoids. Compound (Ib) and three of the known flavonoids lead to more than 2-fold increase in death receptor 5 (DR5) promoter activity at 17.5 or 35 µM. — (OHTSUKI, T.; HIRAKA, T.; KIKUCHI, H.; KOYANO, T.; KOWITHAYAKORN, T.; SAKAI, T.; ISHIBASHI*, M.; Heterocycles 77 (2009) 2, 1379-1388; Grad. Sch. Pharm. Sci., Chiba Univ., Inage, Chiba 263, Japan; Eng.) — M. Bohle 28- 195

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Page 1: ChemInform Abstract: Flavonoids from Eupatorium Odoratum with Death Receptor 5 Promoter Enhancing Activity

www.cheminform.wiley-vch.de

Other bioactive productsU 1300 Flavonoids from Eupatorium Odoratum with Death Receptor 5 Promoter

Enhancing Activity. — Two new flavonoids (I) are isolated from the leaves of Eupa-torium odoratum together with 14 known flavonoids. Compound (Ib) and three of the known flavonoids lead to more than 2-fold increase in death receptor 5 (DR5) promoter activity at 17.5 or 35 µM. — (OHTSUKI, T.; HIRAKA, T.; KIKUCHI, H.; KOYANO, T.; KOWITHAYAKORN, T.; SAKAI, T.; ISHIBASHI*, M.; Heterocycles 77 (2009) 2, 1379-1388; Grad. Sch. Pharm. Sci., Chiba Univ., Inage, Chiba 263, Japan; Eng.) — M. Bohle

28- 195

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