cheminform abstract: facile preparation of 1,2-diketones

ChemInform 2010, 41, issue 51 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de C-C bond formation O 0282 DOI: 10.1002/chin.201051045 Facile Preparation of 1,2-Diketones. — The method is suitable for the preparation of both symmetrical and nonsymmetrical 1,2-diketones. Intermediary formed keto-cyano- hydrins can be isolated, but a one-pot procedure is more convenient. Reactions with 4-pyridinyl substrates fail. — (NOWAK*, P.; MALWITZ, D.; COLE, D. C.; Synth. Commun. 40 (2010) 14, 2164-2171, DOI:10.1080/00397910903219575 ; Chem. Sci. Div., Wyeth-Ayerst Res., Pearl River, NY 10965, USA; Eng.) — H. Haber 51- 045

Upload: pawel-nowak

Post on 11-Jun-2016

213 views

Category:

Documents

0 download

Report

Download

Embed Size (px):

TRANSCRIPT

Page 1: ChemInform Abstract: Facile Preparation of 1,2-Diketones

www.cheminform.wiley-vch.de

C-C bond formationO 0282 DOI: 10.1002/chin.201051045

Facile Preparation of 1,2-Diketones. — The method is suitable for the preparation of both symmetrical and nonsymmetrical 1,2-diketones. Intermediary formed keto-cyano-hydrins can be isolated, but a one-pot procedure is more convenient. Reactions with 4-pyridinyl substrates fail. — (NOWAK*, P.; MALWITZ, D.; COLE, D. C.; Synth. Commun. 40 (2010) 14, 2164-2171, DOI:10.1080/00397910903219575 ; Chem. Sci. Div., Wyeth-Ayerst Res., Pearl River, NY 10965, USA; Eng.) — H. Haber

51- 045

Facile Facile 0

Reclamare Facile

RESEARCHARTICLE Assessingtheinformationcontent ......Rodríguez‑Pérezet al. J Cheminform Page6of14 whichyieldedmedianMCCvaluesof0.67(IFP_85) and0.63(EFCP_folded).us,inhibitorswithbinding

Open Access CSgator:kanjintegratedkwebkplatformk forjcompoundksetkanalysis · 2019. 3. 4. · Parkjet al. J Cheminform Pagek6kofk8 currentlackofenoughcompound-targetdataevenafter

LaTeX Facile

Vegan facile

RESEARCHARTICLE OpAccess ......Jiangiet al. J Cheminform Pagej2jofj26 playerindrugabsorption,distribution,metabolism, excretion,andtoxicity(ADMET)[5, 6],andhasalsobeen

L’économie facile…

METHODOLOGY Ecientiterativevirtualscreening with … · 2018. 3. 1. · Ahmed et al. J Cheminform Page4of8 10contain‘high-scoring’ligands.eunassignedbin3is excludedfromtraining.Figure

L'Arabesque facile

ChemInform RxnFinder