cheminform abstract: f-11334s, new inhibitors of membrane-bound neutral sphingomyelinase
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2000 other bioactive products
other bioactive productsU 1300
07 - 225F-11334s, New Inhibitors of Membrane-Bound Neutral Sphingomyeli-nase. — Five natural products (I), (II), (III) are isolated from Acremoniummurorum and found to have inhibitory activity towards magnesium-dependentsphingomyelinase. Derivatives (I) show the best activity due to free hydroxylgroups in the hydroquinone moiety. — (TANAKA, MASAHIRO; NARA,FUTOSHI; YAMASATO, YOKO; ONO, YASUNORI; OGITA, TAKESHI; J.Antibiot. 52 (1999) 9, 827-830; Biosci. Res. Lab., Sankyo Co., Ltd., Shinagawa,Tokyo 140, Japan; EN)
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