Chemical Information Retrieval Final Exam2009

Drexel University - Instructor: Jean-Claude Bradley

1. Give 5 examples of primary sources (5 points)

2. Give 5 examples of secondary or tertiary sources (5 points)

3. Give 5 examples of sections in a typical journal article (5 points)

4. Give 5 examples of article-level metrics (5 points)

5. Give 3 examples of Creative Commons licenses (3 points)

6. List 2 of the 4 criteria used to determine if the use of a copyrighted work is consideredfair (2 points)

7. List 5 free chemistry databases (5 points)

8. List 3 commercial chemistry databases that Drexel provides (3 points)

All Questions below 1 point each

9. What does DOI stand for?

10. The Beilstein Journal of Organic Chemistry charges this much for publicationa. nothingb. $400c. $800d. $1700e. 23 to 38 Euros per pagef. $95 per page

11. The printing press was invented in:a. 1236b. 1336c. 1436d. 1536e. 1636

12. In a double-blind review:a. the editor and reviewers don't know who the author isb. the editor and author don't know who the reviewers arec. the editor knows who the author and reviewers ared. the author knows who the editor and reviewers aree. the reviewers don't know who the editor and author are

13. In an open review systema. the author may recommend reviewersb. the author may not recommend reviewersc. the author must recommend reviewersd. the reviewer may not know who the author ise. the editor must use one of the author's recommended reviewers

14. The 2005 Thomson Impact Factor is calculated bya. dividing the number of citations in 2005 by the number of citable articles in 2005b. dividing the number of citations in 2005 by the number of citable articles in 2004c. dividing the number of citations in 2005 and 2004 by the number of citable articles in2004 and 2005d. dividing the number of citations in 2004 and 2003 by the number of citable articles in2004 and 2003e. dividing the number of citations in 2005, 2004 and 2003 by the number of citable articlesin 2005, 2004 and 2003

15. How many ILL requests may Drexel undergraduates make in a term?a. 0b. 5c. 10d. 20e. 100f. unlimited

16. The American Chemical Societya. does not permit self-archiving under any conditionsb. does permit self-archiving under any conditionsc. permits self-archiving for papers resulting from work funded by the National ScienceFoundationd. allows authors to pay to make their articles Open Accesse. pays authors to self-archive their papers

17. Drexel's repository is an example ofa. Green Accessb. Gold Accessc. Green and Gold Accessd. neither Green or Golde. Drexel does not have a repository

18. Which of the following takes into account the importance of incoming citations?a. Thomson Impact Factorb. Eigenfactorc. Web of Scienced. Citation Summary Factore. none of the above

19. During peer review:a. reviewers must repeat at least one experiment in the submitted paperb. reviewers are expected to redo every calculation in the submitted paperc. reviewers are paid at least minimum wage for their effortd. reviewers ensure that nonsense cannot be included in the peer-reviewed literaturee. none of the above

20. What percentage of Open Access chemistry journals charge a publication fee?a. 0%b. 42%c. 49%d. 9%e. 100%

21. Harold Varmus founded:a. PubChemb. Public Library of Sciencec. arXivd. PNASe. Thomson Impact Factor

22. Many identifiers can be associated with a chemical structure. Which of these is MOSTappropriate to enable structure based searching across the internet via Google?a. Molfileb. InChI Stringc. InChIKeyd. ChemSpider ID

23. Which of the following identifiers can be used to resolve to a scientific article on theweb.a. CAS Numberb. Digital Object Identifierc. InChI Keyd. Publication ID

24. Which of the following structure databases offers the ability for crowdsourced curation ofthe data?a. PubChemb. ChemSpiderc. Sigma Aldrich websited. NIST Webbook

25. If two molecules are identical what is their Tanimoto similarity?a. 0.5b. 0.0c. 1.0d. 1.5

26. Suppose we define a fingerprint of 4 bits: Bit 1 (from the left) corresponds to thepresence of aromaticity, bit 2 corresponds to the presence of carboxyl groups, bit 3corresponds to the presence of amide bonds and bit 4 corresponds to the presence of anallylic group. With this definition what is the fingerprint for benzoic acid?a. 1100b. 0000c.1111d 1011

27. If you do not have the 3D structure of a protein target, which virtual screening methodcan you *not* usea. QSARb. Substructure searchingc. Dockingd. Similarity searching