chemical product design 2nd edition
TRANSCRIPT
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 1/454
u s s l e r , E .
L . .
C h e m i c a l P r o d u c t D e s i g n ( 2 n d E d i t i o n ) .
C a m b r i d g e U n i v e r s i t y P r e s s , . p 1
t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6 4 8 1 ? p p g = 1
o p y r i g h t ©
C a m b r
i d g e U n i v e r s i t y P r e
s s . .
A l l r i g h t s r e s e r v e d .
a y n o t b e r e p r o d u
c e d i n a n y f o r m w
i t h o u t p e r m i s s i o n f r o
m t h
e p u b l i s h e r , e x
c e p t f a i r u s e s p e r m
i t t e d u n d e r U . S . o
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 2/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 3/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 4/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 5/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 6/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 7/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 8/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 9/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 10/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 11/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 12/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 13/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 14/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 15/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 16/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 17/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 18/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 19/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 20/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 21/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 22/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 23/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 24/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 25/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 26/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 27/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 28/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 29/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 30/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 31/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 32/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 33/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 34/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 35/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 36/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 37/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 38/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 39/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 40/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 41/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 41
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=41
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 42/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 42
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=42
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 43/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 43
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=43
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 44/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 44
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=44
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 45/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 45
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=45
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 46/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 46
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=46
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 47/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 47
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=47
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 48/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 48
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=48
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 49/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 49
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=49
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 50/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 50
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=50
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 51/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 51
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=51
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 52/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 52
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=52
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 53/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 53
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=53
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 54/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 54
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=54
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 55/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 55
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=55
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 56/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 56
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=56
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 57/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 57
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=57
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 58/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 58
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=58
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 59/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 59
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=59
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 60/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 60
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=60
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 61/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 61
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=61
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 62/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 62
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=62
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 63/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 63
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=63
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 64/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 64
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=64
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 65/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 65
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=65
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 66/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 66
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=66
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 67/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 67
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=67
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 68/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 68
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=68
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 69/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 69
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=69
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 70/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 70
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=70
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 71/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 71
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=71
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 72/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 72
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=72
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 73/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 73
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=73
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 74/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 74
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=74
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 75/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 75
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=75
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 76/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 76
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=76
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 77/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 77
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=77
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 78/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 78
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=78
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 79/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 79
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=79
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 80/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 80
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=80
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 81/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 81
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=81
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 82/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 82
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=82
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 83/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 83
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=83
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 84/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 84
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=84
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 85/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 85
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=85
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 86/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 86
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=86
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 87/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 87
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=87
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 88/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 88
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=88
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 89/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 89
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=89
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 90/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 90
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=90
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 91/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 91
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=91
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 92/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 92
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=92
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 93/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 93
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=93
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 94/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 94
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=94
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 95/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 95
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=95
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 96/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 96
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=96
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 97/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 97
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=97
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 98/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 98
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=98
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 99/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 99
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=99
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 100/454
Cussler, E. L.. Chemical Product Design (2nd Edition).
Cambridge, GBR: Cambridge University Press, 2011. p 100
ttp://site.ebrary.com/lib/bppt/Doc?id=10476481&ppg=100
Copyright © 2011. Cambridge University Press. All r ights Reserved.
May not be reproduced in any form without permission from the publisher, except fair uses permitted under U.S. or applicable copyright law.
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 101/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 102/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 103/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 104/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 105/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 106/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 107/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 108/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 109/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 0 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 0 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 110/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 111/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 112/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 113/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 114/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 115/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 116/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 117/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 118/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 119/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 1 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 1 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 120/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 121/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 122/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 123/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 124/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 125/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 126/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 127/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 128/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 129/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 2 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 2 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 130/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 131/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 132/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 133/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 134/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 135/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 136/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 137/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 138/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 139/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 3 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 3 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 140/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 141/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 142/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 143/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 144/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 145/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 146/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 147/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 148/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 149/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 150/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 4 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 4 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 151/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 152/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 153/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 154/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 155/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 156/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 157/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 158/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 159/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 160/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 5 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 5 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 161/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 162/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 163/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 164/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 165/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 166/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 167/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 168/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 169/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 170/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 6 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 6 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 171/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 172/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 173/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 174/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 175/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 176/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 177/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 178/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 179/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 180/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 7 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 7 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 181/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 182/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 183/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 184/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 185/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 186/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 187/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 188/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 189/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 190/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 8 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 8 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 191/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 192/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 193/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 194/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 195/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 196/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 197/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 198/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 199/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 200/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 1 9 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 1 9 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 201/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 202/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 203/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 204/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 205/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 206/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 207/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 208/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 209/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 210/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 0 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 0 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 211/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 212/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 213/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 214/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 215/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 216/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 217/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 218/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 219/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 220/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 1 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 1 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 221/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 222/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 223/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 224/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 225/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 226/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 227/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 228/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 229/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 230/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 2 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 2 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 231/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 232/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 233/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 234/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 235/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 236/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 237/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 238/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 239/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 240/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 3 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 3 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 241/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 242/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 243/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 244/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 245/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 246/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 247/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 248/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 249/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 250/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 4 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 4 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 251/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 252/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 253/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 254/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 255/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 256/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 257/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 258/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 259/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 260/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 5 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 5 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 261/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 262/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 263/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 264/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 265/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 266/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 267/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 268/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 269/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 270/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 6 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 6 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 271/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 272/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 273/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 274/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 275/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 276/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 277/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 278/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 279/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 280/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 7 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 7 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 281/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 282/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 283/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 284/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 285/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 286/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 287/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 288/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 289/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 290/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 8 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 8 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 291/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 292/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 293/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 294/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 295/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 296/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 297/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 298/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 299/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 300/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 2 9 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 2 9 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 301/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 302/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 303/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 304/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 305/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 306/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 307/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 308/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 309/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 310/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 0 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 0 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 311/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 312/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 313/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 314/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 315/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 316/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 317/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 318/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 319/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 320/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 1 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 1 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 321/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 322/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 323/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 324/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 325/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 326/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 327/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 328/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 329/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 330/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 2 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 2 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 331/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 332/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 333/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 334/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 335/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 336/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 337/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 338/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 339/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 340/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 3 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 3 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 341/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 342/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 343/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 344/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 345/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 346/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 347/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 348/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 349/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 350/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 4 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 4 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 351/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 352/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 353/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 354/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 355/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 356/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 357/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 358/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 359/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 360/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 5 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 5 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 361/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 362/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 363/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 364/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 365/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 366/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 367/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 368/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 369/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 370/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 6 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 6 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 371/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 372/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 373/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 374/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 375/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 376/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 377/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 378/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 379/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 380/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 7 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 7 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 381/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 382/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 383/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 384/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 385/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 386/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 387/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 388/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 389/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 390/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 8 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 8 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 391/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 392/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 393/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 394/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 395/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 396/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 397/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 398/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 399/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 400/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 3 9 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 3 9 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 401/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 402/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 403/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 404/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 405/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 406/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 407/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 408/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 409/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 410/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 0 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 0 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 411/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 412/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 413/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 414/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 415/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 416/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 417/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 418/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 419/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 420/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 1 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 1 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 421/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 422/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 423/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 424/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 425/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 426/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 427/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 428/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 429/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 430/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 2 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 2 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 431/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 432/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 433/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 434/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 435/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 436/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 437/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 438/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 439/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 440/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 3 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 3 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 441/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 442/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 443/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 444/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 3
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 3
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 445/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 4
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 4
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 446/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 5
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 5
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 447/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 6
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 6
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 448/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 7
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 7
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 449/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 8
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 8
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 450/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 4 9
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 4 9
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 451/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 5 0
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 5 0
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 452/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 5 1
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 5 1
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 453/454 C u s s l e r , E . L . . C h e m i c a l P r o d
u c t D e s i g n ( 2 n d E d i t i o n ) .
: C a m b r i d g e U n i v e r s i t y P r e s s , . p 4 5 2
h t t p : / / s i t e . e
b r a r y . c o m / i d / 1 0 4 7 6
4 8 1 ? p p g = 4 5 2
C o p y r i g h t ©
C a m b r i d g e U n i v e
r s i t y P r e s s . .
A l l r i g h t s r e s e r v e d .
M a y n o t b e r e p r o d u c e d i n a n y
f o r m w
i t h o u t p e r m i s s i o n f r o m t h
e p u b
l i s h e r , e x c e p t f a i r u s e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .
8/21/2019 Chemical Product Design 2nd Edition
http://slidepdf.com/reader/full/chemical-product-design-2nd-edition 454/454
e s p e r m i t t e d u n d e
r U . S . o r a p p l i c a b l e c o p y r i g h t l a w .